Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T14777 |
BRD5529
|
Others | Others |
BRD5529 is a selective inhibitor of CARD9-E3 ubiquitin ligase TRIM62 protein-protein interaction (IC50: 8.6 μM). BRD5529 directly and selectively binds CARD9, disrupts TRIM62 recruitment, inhibits TRIM62-mediated ubiquitinylation, and activation of CARD9. |