Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T70659 |
BR103
|
Others | Others |
BR103 is a C3aR-selective agonist that is metabolically stable. | |||
T70657 |
Ormosinine
|
Others | Others |
Ormosinine is an inhibitor of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase. | |||
T69603 |
BR103354
|
Others | Others |
BR103354 is a novel fibroblast activation protein (FAP) inhibitor with anti-diabetic and anti-steatotic effects. BR103354 inhibited FAP with an IC50 value of 14 nM, showing high selectivity against dipeptidyl peptidase (DPP)-related enzymes and prolyl oligopeptidase (PREP). BR103354 exhibited good pharmacokinetic properties as evidenced by oral bioavailability of 48.4% and minimal hERG inhibition. Single co-administration of BR103354 with hFGF21 reduced nonfasting blood glucose concentrations, i... |