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Targets Recommended: Apoptosis PD-1/PD-L1

100

抑制剂 & 化合物

1732

重组蛋白

1

同位素标记化合物

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Cat. No. Product Name Target Signaling Pathways
T3655 BMS-1

PD1-PDL1 inhibitor 1,PD-1/PD-L1 inhibitor 1

Apoptosis; PD-1/PD-L1 Apoptosis; Cell Cycle/Checkpoint; Immunology/Inflammation
BMS-1 (PD-1/PD-L1 inhibitor 1)是一种 PD-1/PD-L1蛋白质/蛋白质相互作用的抑制剂,IC50为 6 到 100 nM。
T5398 BMS 599626 2HCl (873837-23-1(HCl))

AC480 dihydrochloride

HER Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
BMS 599626 2HCl (873837-23-1(HCl)) (AC480 dihydrochloride) 是 HER1 和 HER2 的选择性抑制剂(IC50:20 nM 和 30 nM),对 HER4 的效力降低约 8 倍,对 Lck、VEGFR2、c-Kit、MET 等的效力降低 100 倍以上。
T26859 BMS-8

PD-1/PD-L1 Apoptosis; Cell Cycle/Checkpoint; Immunology/Inflammation
BMS-8 抑制PD-1/PD-L1相互作用(IC50:7.2 μM)。它能够直接与 PD-L1 结合,促使形成 PD-L1 同源二聚体,进而阻断 PD-L1 与 PD-1 的相互作用。
T7512 BMS-191011

BMS-A

Potassium Channel Membrane transporter/Ion channel
BMS-191011 (BMS-A) 是一种大电导 Ca2+激活的钾通道 (Ca2+-activated potassium (maxi-K) channel) 激活剂,在中风模型中有研究价值。
T6864 Ixabepilone

BMS 247550,Ixempra,Azaepothilone B,伊沙匹隆,BMS 247550-1

Apoptosis; Microtubule Associated Apoptosis; Cytoskeletal Signaling
Ixabepilone (Azaepothilone B) 是一种可口服的微管抑制剂,能够与微管蛋白结合,促进微管蛋白的聚合和微管的稳定,使细胞停滞在 G2-M 期,诱导细胞凋亡。
T35856 BMS-986176

AAK1 (AP2 associated kinase 1) Neuroscience
BMS-986176 是一种有效的AAK1 抑制剂,IC50为 2.2 nM。BMS-986176在神经退行性疾病中有研究的价值。
T6418 BMS-378806

BMS378806,BMS-806,1-[(2R)-4-苯甲酰基-2-甲基-1-哌嗪基]-2-(4-甲氧基-1H-吡咯并[2,3-B]吡啶-3-基)-1,2-乙二酮

gp120/CD4; HIV Protease Immunology/Inflammation; Microbiology/Virology; Proteases/Proteasome
BMS-378806 (BMS-806) 是一种 HIV-1 抑制剂,可选择性抑制 HIV-1 gp120 结合到 CD4 受体,EC50为 0.85-26.5 nM。
T22612 BMY-14802 hydrochloride

BMS 181100 hydrochloride,BMY-14802-1,BMY 14802 hydrochloride

Sigma receptor; 5-HT Receptor; Adrenergic Receptor GPCR/G Protein; Neuroscience
BMY-14802 hydrochloride (BMS 181100 hydrochloride) 是一种选择性的 σ 受体拮抗剂 (IC50 = 112 nM),具有抗精神病作用。 BMY-14802 hydrochloride 是 α1-肾上腺素能受体和 5-HT1A 的激动剂。
T8991 BMS986187

Opioid Receptor Endocrinology/Hormones; GPCR/G Protein; Neuroscience
BMS986187 是一种有效的δ-阿片受体选择性正变构调节剂 (PAM),其 EC50= 0.03 μM,pKB= 6.02 (~1 μM)。BMS986187 对 μ 受体无明显 PAM 活性 (EC50=3 μM)。
T1786 Daclatasvir dihydrochloride

BMS-790052 dihydrochloride,盐酸达拉他韦

HCV Protease Microbiology/Virology; Proteases/Proteasome
Daclatasvir dihydrochloride (BMS-790052 dihydrochloride) 是有机阴离子转运多肽 1B(OATP1B) 和 OATP1B3抑制剂,IC50分别为 1.5 µM 和 3.27 µM。它也具有口服活性的 HCV NS5A 蛋白抑制剂,多种 HCV 复制子基因型的 EC50范围为 9-146 pM。
T6229 Daclatasvir

Daklinza,达卡他韦,EBP 883,达拉他韦,BMS-790052

HCV Protease Microbiology/Virology; Proteases/Proteasome
Daclatasvir (EBP 883) 是一种高度选择性的 HCV NS5A 抑制剂,EC50 为 9-50 pM,适用于细胞培养中的多种 HCV 复制子基因型和 JFH-1 基因型 2a 感染性病毒。
T3146 BMS-202

PD1-PDL1 inhibitor 2,PD-1/PD-L1 inhibitor 2

Apoptosis; PD-1/PD-L1 Apoptosis; Cell Cycle/Checkpoint; Immunology/Inflammation
BMS-202 (PD1-PDL1 inhibitor 2) 是一种非肽类 PD-1/PD-L 复合物抑制剂,其 IC50为 18 nM,KD 为 8 μM。它与 PD-L1 直接结合并阻断人类 PD-1/PD-L 的相互作用,具有抗肿瘤活性。
T0100 Atazanavir sulfate

阿扎那韦硫酸盐,BMS-232632,BMS-232632 sulfate,硫酸阿扎那韦

P450; SARS-CoV; HIV Protease; P-gp Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Neuroscience; Proteases/Proteasome
Atazanavir sulfate (BMS-232632 sulfate) 是一种氮杂肽和 HIV 蛋白酶抑制剂,与其他抗 HIV 药物联合用于治疗 HIV 感染和艾滋病。它也是SARS-CoV 3CLpro 抑制剂,IC50为 3.49 μM。
T0178 Saxagliptin hydrate

沙格列汀单水化合物,Onglyza hydrate,BMS-477118 hydrate

Proteasome; DPP-4 Proteases/Proteasome; Ubiquitination
Saxagliptin hydrate (Onglyza hydrate) 是一种选择性,竞争性,可逆性和口服活性的二肽基肽酶 4 (DPP-4) (Ki= 0.6-1.3 nM) 抑制剂。Saxagliptin hydrate 能够用于 2 型糖尿病的研究。
T6203 Saxagliptin

BMS-477118,沙克列汀,Onglyza,沙格列汀

Proteasome; DPP-4 Proteases/Proteasome; Ubiquitination
Saxagliptin (BMS-477118) 是一种选择性,可逆性,竞争性和口服活性的二肽基肽酶 4 (DPP-4) (Ki= 0.6-1.3 nM) 抑制剂。Saxagliptin 能够用于 2 型糖尿病的研究。
T0085 Entecavir monohydrate

SQ 34676,BMS-200475,Entecavir hydrate,恩替卡韦 (1水合物),恩替卡韦一水合物

HBV Microbiology/Virology
Entecavir monohydrate (BMS-200475) 是一种选择性HBV 抑制剂,在HepG2细胞中的EC50值为3.75 nM。
T1615 Irbesartan

厄贝沙坦,SR-47436,BMS-186295

Apoptosis; RAAS Apoptosis; Endocrinology/Hormones
Irbesartan (SR-47436) 是一种 1 型血管紧张素 II 受体拮抗剂,IC50为1.3 nM。
T0100L Atazanavir

Zrivada,Reyataz,Latazanavir,阿扎那韦,BMS-232632

P450; SARS-CoV; HIV Protease; P-gp Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Neuroscience; Proteases/Proteasome
Atazanavir (BMS-232632) 是一种高选择性的HIV-1蛋白酶抑制剂,可研究艾滋病毒感染。它也是SARS-CoV 3CLpro 的抑制剂,IC50为 3.49 μM。它是CYP3A4的底物和抑制剂,也是P-糖蛋白的抑制剂和诱导剂。
T6419 BMS-536924

HY-10262,胰岛素样生长因子-1 受体拮抗剂,BMS 536924,CS-0117

Apoptosis; FAK; MEK; IGF-1R; Src Angiogenesis; Apoptosis; Cytoskeletal Signaling; MAPK; Tyrosine Kinase/Adaptors
BMS-536924 (BMS 536924) 是一种具有口服活性,竞争性和选择性的胰岛素样生长因子受体激酶和胰岛素受体抑制剂,IC50分别为 100 nM 和 73 nM。它具有抗癌活性。
T6420 BMS-707035

N-[(4-氟苯基)甲基1,6-二氢-5-羟基-1-甲基-6-氧代-2-(四氢-1,1-二氧-2H-1,2-噻嗪-2-基)-4-嘧啶甲酰胺

HIV Protease Microbiology/Virology; Proteases/Proteasome
BMS707035是一种 HIV-1 整合酶抑制剂,IC50为15 nM。
T7787 BMS817378

[3-[[4-((2-氨基-3-氯吡啶-4-基)氧基)-3-氟苯基]氨基甲酰基]-5-(4-氟苯基)-4-氧代-4H-吡啶-1-基]甲基磷酸二氢酯

c-Met/HGFR Tyrosine Kinase/Adaptors
BMS817378 是一种有效的选择性 MET 抑制剂 (IC50 : 1.7 nM)。
T5164 Cabozantinib hydrochloride

XL184,Cabozantinib hydrochloride (849217-68-1(free base)),BMS-907351,盐酸卡博替尼

VEGFR; FLT; c-Met/HGFR; TAM Receptor; c-Kit; ROR Angiogenesis; Metabolism; Tyrosine Kinase/Adaptors
Cabozantinib hydrochloride (XL184) 是一种有效的泛酪氨酸激酶抑制剂,可抑制 VEGFR2、c-Met、Kit、Axl 和 Flt4(IC50:0.035、1.3、4.6、7 和 6 nM)。
T11740L Delcasertib acetate

KAI-9803,KID1-1,CS-9803,BMS-875944,Delcasertib acetate(949100-39-4 free base)

PKC Chromatin/Epigenetic; Cytoskeletal Signaling
Delcasertib acetate 是一种选择性 δ 蛋白激酶C (δPKC) 抑制剂,可用于研究急性心肌梗死和疼痛。
T28354 Peliglitazar

BMS-426707-1,BMS 42670701,BMS 426707-01

Others Others
Peliglitazar is a activator of α/γ peroxisome proliferator-activated receptor.
T4696 BMS202 hydrochloride (1675203-84-5(free base))

PD-1/PD-L1 inhibitor 2 hydrochloride

PD-1/PD-L1 Apoptosis; Cell Cycle/Checkpoint; Immunology/Inflammation
BMS202 hydrochloride (1675203-84-5(free base)) (PD-1/PD-L1 inhibitor 2 hydrochloride) 是一种小分子 PD-1/PD-L1 相互作用抑制剂 (IC50: 18 nM)。生物物理研究表明 BMS202 直接与 PD-L1 结合。 BMS202 的结合促进 PD-L1 二聚化并阻断 PD-L1/PD1 相互作用。
T14677 BMS-690514

EGFR; VEGFR; HER Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
BMS-690514是可口服的EGFR 和VEGFR 抑制剂,对于EGFR、HER2和HER4的IC50值分别为5、9 和 60 nM。
T2610 BMS-599626

AC480

EGFR; MEK; HER; Src Angiogenesis; JAK/STAT signaling; MAPK; Tyrosine Kinase/Adaptors
BMS-599626 (AC480) 是可口服的选择性 HER1和HER2抑制剂,IC50分别为 20 和 30 nM。它对 HER4 的 IC50值为 190 nM,可抑制肿瘤细胞增殖,有治疗肿瘤的潜力。
T14676 BMS-688521

Integrin Cytoskeletal Signaling
BMS-688521 是一种具有口服活性和高效性的 LFA-1/ICAM 相互作用抑制剂,是白细胞功能相关抗原-1 (LFA-1) 的小分子拮抗剂,具有潜在的抗炎活性。
T3523 Fostemsavir

BMS-663068,磷坦姆沙韦

HIV Protease Microbiology/Virology; Proteases/Proteasome
Fostemsavir (BMS-663068) 是 BMS-626529 的原药,可抑制 HIV-1 与细胞 CD4 受体的结合,能结合gp120。
T10570 Fostemsavir Tris

BMS-663068 Tris

HIV Protease Microbiology/Virology; Proteases/Proteasome
Fostemsavir Tris (BMS-663068 Tris) 是一种 HIV-1附着抑制剂。
T40111L BMS-1166-N-piperidine-CO-N-piperazine dihydrochloride

PD-1/PD-L1 Apoptosis; Cell Cycle/Checkpoint; Immunology/Inflammation
BMS-1166-N-piperidine-CO-N-piperazine dihydrochloride 是一种基于间苯二酚二Ph醚支架的程序性细胞死亡-1(PD-1)/程序性细胞死亡配体1(PD-L1)抑制剂, 抑制 PD-1/PD-L1 相互作用,IC50 值为 39.2 nM.BMS-1166-N-piperidine-CO-N-piperazine dihydrochloride 包含靶蛋白 PD-1/PD-L1 配体和 PROTAC linker。BMS-1166-N-piperidine-CO-N-piperazine dihydrochloride 可用于合成 PROTAC PD-1/PD-L1 degrader-1BMS-1166-N-piperidine-CO-N-piperazine dihydrochloride 具有抗癌活性。BMS-1166-N-piperidine-CO-N-piperazine dihydrochloride 可作为稀释剂,用于用于直接压缩制备片剂。
T4532 Linrodostat

BMS-986205

IDO; Indoleamine 2,3-Dioxygenase (IDO) Metabolism
Linrodostat (BMS-986205) 是选择性的、不可逆的吲哚胺 2,3-双加氧酶 1(IDO1) 抑制剂,能够有效抑制 IDO1-HEK293 细胞,其IC50=1.1 nM。它在晚期癌症中具有良好的药理特性。
T71394 BMS-823778

Dehydrogenase Metabolism
BMS-823778 是一种高效的 11β-羟基类固醇脱氢酶 1 型(11β-HSD-1)的抑制剂,可用于研究 2 型糖尿病。
T6326 BMS-345541

BMS-345541 free base,IKK Inhibitor III,BMS345541

IκB/IKK NF-κB
BMS-345541 (IKK Inhibitor III) 是选择性的 IKK 催化亚基 IKK-1 和 IKK-2 抑制剂,抑制 IKK-2 (IC50=0.3 nM) 和 IKK-1 (IC50=4 nM)。它与 IKK 的变构位点结合。
T8470 BMS-1001

PD-1/PD-L1 Apoptosis; Cell Cycle/Checkpoint; Immunology/Inflammation
BMS-1001 是一种有效的 PD-1/PD-L1 相互作用抑制剂(IC50:2.25 nM,在均相时间分辨荧光结合试验中)。
T26869 BMS-986122

BMS 986122

Opioid Receptor Endocrinology/Hormones; GPCR/G Protein; Neuroscience
BMS-986122 (BMS 986122) 是选择性 μ 阿片受体正变构调节剂,可增加 β-抑制蛋白募集、腺苷酸环化酶抑制和 G 蛋白活化的作用,还增强 DAMGO 介导的 [35S]GTPγS 在小鼠脑膜中的结合。
T6036 Brivanib

BMS-540215,布立尼布

EGFR; VEGFR; FGFR; Autophagy Angiogenesis; Autophagy; JAK/STAT signaling; Tyrosine Kinase/Adaptors
Brivanib (BMS-540215) 是一种针对 VEGFR2 的 ATP 竞争性抑制剂,IC50 为 25 nM。它对 VEGFR-1 和 FGFR-1 具有中等效力,对 VEGFR2 的选择性是对 PDGFR-β 的 240 倍。
T10565 BMS-1001 hydrochloride

PD-1/PD-L1 Apoptosis; Cell Cycle/Checkpoint; Immunology/Inflammation
BMS-1001 hydrochloride 是一种人 PD-L1/PD-1免疫检查点的抑制剂,具有口服活性且细胞毒性低。
T14688 BMS CCR2 22

CCR Immunology/Inflammation; Microbiology/Virology
BMS CCR2 22 是一种有效的选择性 CC 型趋化因子受体2拮抗剂,钙通量 IC50为 18 nM,趋化性 IC50为1 nM,结合 IC50为5.1 nM。
T9164 BMS-986242

BMS986242

IDO; Indoleamine 2,3-Dioxygenase (IDO) Metabolism
BMS-986242 是具有口服具有活力、强效的、选择性的 indoleamine-2,3-dioxygenase 1 抑制剂,可用于研究癌症。
T5697 BMS-1166

PD-1/PD-L1 Apoptosis; Cell Cycle/Checkpoint; Immunology/Inflammation
BMS-1166 是 PD-1/PD-L1免疫检查点抑制剂。它促使 PD-L1 形成 PD-L1 同源二聚体,进而阻断其与 PD-1 的相互作用,其 IC50为 1.4 nM。它阻断了 PD-1/PD-L1 免疫检查点对 T 细胞活化的抑制作用。
T8542 BMS-345541 hydrochloride

N-(1,8-二甲基咪唑并[1,2-A]喹喔啉-4-基)-1,2-乙二胺盐酸盐

IκB/IKK NF-κB
BMS-345541 hydrochloride 是选择性的 IKK 催化亚基 IKK-1 和 IKK-2 抑制剂,抑制 IKK-2 (IC50=0.3 nM) 和 IKK-1 (IC50=4 nM)。它与 IKK 的变构位点结合。
T6790 BMS-911543

BMS911543

Tyrosine Kinases; Histone Methyltransferase; JAK Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells; Tyrosine Kinase/Adaptors
BMS-911543 是一种选择性 JAK2抑制剂,IC50值为 1.1 nM,对 JAK1、JAK3 和 TYK2 的选择性相对较弱,IC50值分别为 75、360 和 66 nM。
T39647 BMS-986278

LPA Receptor GPCR/G Protein
BMS-986278 是一种具有口服活性和高效性的血磷脂酸受体 1 (LPA1) 拮抗剂,对人和小鼠 LPA1 的 Kb 值分别为 6.9 nM 和 4.0 nM。BMS-986278 可用于研究用于特发性肺纤维化。
T10493 Beclabuvir

BMS-791325

HCV Protease Microbiology/Virology; Proteases/Proteasome
Beclabuvir (BMS-791325) 是一种高效的 NS5A 复制复合物抑制剂,抑制 HCV 基因型 1,2,4,5 表达的 NS5B 蛋白活性,可用于研究 HCV 感染。
T30527 BMS-488043

CHEMBL238103,UNII-MKS21EJ435,BMS 043,BMS488043,BMS 488043

HIV Protease Microbiology/Virology; Proteases/Proteasome
BMS-488043 是一种新颖独特的口服小分子HIV融合抑制剂,可抑制人类免疫缺陷病毒 1 型(HIV-1)附着于 CD4(+)淋巴细胞。BMS-488043 可用于治疗免疫系统疾病、感染和泌尿生殖系统疾病,可用与研究HIV感染。
T4016 BMS-986020

AM152,BMS986020

LPA Receptor; LPL Receptor GPCR/G Protein
BMS-986020 (AM152) 是一种高亲和力溶血磷脂酸受体 1 拮抗剂,有用于特发性肺纤维化的研究潜力。它抑制胆汁酸和磷脂转运蛋白,抑制 BSEP、MRP4 和 MDR3,IC50值分别为 4.8、6.2 和 7.5 μM。
T76741 Eldelumab

BMS-936557,MDX-1100

CXCR Autophagy; GPCR/G Protein; Immunology/Inflammation
Eldelumab (BMS-936557) 是一种人源化抗 IP-10 IgG 1型单克隆抗体,对 CXCL10 具有抑制作用。Eldelumab 具有抗炎活性,可与 CXCL10 结合,可用于研究类风湿性关节炎。
T2349 BMS-754807

Trk receptor; c-Met/HGFR; IGF-1R Tyrosine Kinase/Adaptors
BMS754807 是一种可逆的IGF-1R 抑制剂 (IC50:1.8 nM,Ki<2 nM),也是一种可逆的IR 抑制剂 (IC50:7 nM,Ki<2 nM)。它也抑制 Met (IC50:6 nM),RON (IC50:44 nM),TrkA (IC50:7 nM),TrkB (IC50:4 nM),AurA (IC50:9 nM) 和 AurB (IC50:25 nM) 的活性。
T71265 BMS-830216

Others Others
BMS-830216 is a nonbasic melanin hormone receptor 1 antagonist and a prodrug of BMS-819881.

化合物

BMS-1
Cat.No: T3655
Synonym: PD1-PDL1 inhibitor 1,PD-1/PD-L1 inhibitor 1
Target: Apoptosis, PD-1/PD-L1
BMS 599626 2HCl (873837-23-1(HCl))
Cat.No: T5398
Synonym: AC480 dihydrochloride
Target: HER
BMS-8
Cat.No: T26859
Synonym:
Target: PD-1/PD-L1
BMS-191011
Cat.No: T7512
Synonym: BMS-A
Target: Potassium Channel
Ixabepilone
Cat.No: T6864
Synonym: BMS 247550,Ixempra,Azaepothilone B,伊沙匹隆,BMS 247550-1
Target: Apoptosis, Microtubule Associated
BMS-986176
Cat.No: T35856
Synonym:
Target: AAK1 (AP2 associated kinase 1)
BMS-378806
Cat.No: T6418
Synonym: BMS378806,BMS-806,1-[(2R)-4-苯甲酰基-2-甲基-1-哌嗪基]-2-(4-甲氧基-1H-吡咯并[2,3-B]吡啶-3-基)-1,2-乙二酮
Target: gp120/CD4, HIV Protease
BMY-14802 hydrochloride
Cat.No: T22612
Synonym: BMS 181100 hydrochloride,BMY-14802-1,BMY 14802 hydrochloride
Target: Sigma receptor, 5-HT Receptor, Adrenergic Receptor
BMS986187
Cat.No: T8991
Synonym:
Target: Opioid Receptor
Daclatasvir dihydrochloride
Cat.No: T1786
Synonym: BMS-790052 dihydrochloride,盐酸达拉他韦
Target: HCV Protease
Daclatasvir
Cat.No: T6229
Synonym: Daklinza,达卡他韦,EBP 883,达拉他韦,BMS-790052
Target: HCV Protease
BMS-202
Cat.No: T3146
Synonym: PD1-PDL1 inhibitor 2,PD-1/PD-L1 inhibitor 2
Target: Apoptosis, PD-1/PD-L1
Atazanavir sulfate
Cat.No: T0100
Synonym: 阿扎那韦硫酸盐,BMS-232632,BMS-232632 sulfate,硫酸阿扎那韦
Target: P450, SARS-CoV, HIV Protease, P-gp
Saxagliptin hydrate
Cat.No: T0178
Synonym: 沙格列汀单水化合物,Onglyza hydrate,BMS-477118 hydrate
Target: Proteasome, DPP-4
Saxagliptin
Cat.No: T6203
Synonym: BMS-477118,沙克列汀,Onglyza,沙格列汀
Target: Proteasome, DPP-4
Entecavir monohydrate
Cat.No: T0085
Synonym: SQ 34676,BMS-200475,Entecavir hydrate,恩替卡韦 (1水合物),恩替卡韦一水合物
Target: HBV
Irbesartan
Cat.No: T1615
Synonym: 厄贝沙坦,SR-47436,BMS-186295
Target: Apoptosis, RAAS
Atazanavir
Cat.No: T0100L
Synonym: Zrivada,Reyataz,Latazanavir,阿扎那韦,BMS-232632
Target: P450, SARS-CoV, HIV Protease, P-gp
BMS-536924
Cat.No: T6419
Synonym: HY-10262,胰岛素样生长因子-1 受体拮抗剂,BMS 536924,CS-0117
Target: Apoptosis, FAK, MEK, IGF-1R, Src
BMS-707035
Cat.No: T6420
Synonym: N-[(4-氟苯基)甲基1,6-二氢-5-羟基-1-甲基-6-氧代-2-(四氢-1,1-二氧-2H-1,2-噻嗪-2-基)-4-嘧啶甲酰胺
Target: HIV Protease
BMS817378
Cat.No: T7787
Synonym: [3-[[4-((2-氨基-3-氯吡啶-4-基)氧基)-3-氟苯基]氨基甲酰基]-5-(4-氟苯基)-4-氧代-4H-吡啶-1-基]甲基磷酸二氢酯
Target: c-Met/HGFR
Cabozantinib hydrochloride
Cat.No: T5164
Synonym: XL184,Cabozantinib hydrochloride (849217-68-1(free base)),BMS-907351,盐酸卡博替尼
Target: VEGFR, FLT, c-Met/HGFR, TAM Receptor, c-Kit, ROR
Delcasertib acetate
Cat.No: T11740L
Synonym: KAI-9803,KID1-1,CS-9803,BMS-875944,Delcasertib acetate(949100-39-4 free base)
Target: PKC
Peliglitazar
Cat.No: T28354
Synonym: BMS-426707-1,BMS 42670701,BMS 426707-01
Target: Others
BMS202 hydrochloride (1675203-84-5(free base))
Cat.No: T4696
Synonym: PD-1/PD-L1 inhibitor 2 hydrochloride
Target: PD-1/PD-L1
BMS-690514
Cat.No: T14677
Synonym:
Target: EGFR, VEGFR, HER
BMS-599626
Cat.No: T2610
Synonym: AC480
Target: EGFR, MEK, HER, Src
BMS-688521
Cat.No: T14676
Synonym:
Target: Integrin
Fostemsavir
Cat.No: T3523
Synonym: BMS-663068,磷坦姆沙韦
Target: HIV Protease
Fostemsavir Tris
Cat.No: T10570
Synonym: BMS-663068 Tris
Target: HIV Protease
BMS-1166-N-piperidine-CO-N-piperazine dihydrochloride
Cat.No: T40111L
Synonym:
Target: PD-1/PD-L1
Linrodostat
Cat.No: T4532
Synonym: BMS-986205
Target: IDO, Indoleamine 2,3-Dioxygenase (IDO)
BMS-823778
Cat.No: T71394
Synonym:
Target: Dehydrogenase
BMS-345541
Cat.No: T6326
Synonym: BMS-345541 free base,IKK Inhibitor III,BMS345541
Target: IκB/IKK
BMS-1001
Cat.No: T8470
Synonym:
Target: PD-1/PD-L1
BMS-986122
Cat.No: T26869
Synonym: BMS 986122
Target: Opioid Receptor
Brivanib
Cat.No: T6036
Synonym: BMS-540215,布立尼布
Target: EGFR, VEGFR, FGFR, Autophagy
BMS-1001 hydrochloride
Cat.No: T10565
Synonym:
Target: PD-1/PD-L1
BMS CCR2 22
Cat.No: T14688
Synonym:
Target: CCR
BMS-986242
Cat.No: T9164
Synonym: BMS986242
Target: IDO, Indoleamine 2,3-Dioxygenase (IDO)
BMS-1166
Cat.No: T5697
Synonym:
Target: PD-1/PD-L1
BMS-345541 hydrochloride
Cat.No: T8542
Synonym: N-(1,8-二甲基咪唑并[1,2-A]喹喔啉-4-基)-1,2-乙二胺盐酸盐
Target: IκB/IKK
BMS-911543
Cat.No: T6790
Synonym: BMS911543
Target: Tyrosine Kinases, Histone Methyltransferase, JAK
BMS-986278
Cat.No: T39647
Synonym:
Target: LPA Receptor
Beclabuvir
Cat.No: T10493
Synonym: BMS-791325
Target: HCV Protease
BMS-488043
Cat.No: T30527
Synonym: CHEMBL238103,UNII-MKS21EJ435,BMS 043,BMS488043,BMS 488043
Target: HIV Protease
BMS-986020
Cat.No: T4016
Synonym: AM152,BMS986020
Target: LPA Receptor, LPL Receptor
Eldelumab
Cat.No: T76741
Synonym: BMS-936557,MDX-1100
Target: CXCR
BMS-754807
Cat.No: T2349
Synonym:
Target: Trk receptor, c-Met/HGFR, IGF-1R
BMS-830216
Cat.No: T71265
Synonym:
Target: Others
Cat. No. Product Name Species Expression System
TMPY-04451 AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST)

AMPK, AMPK(α1, β1, γ1)

Human Baculovirus Insect Cells
AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 160 kDa and the accession number is P54619-1&Q9Y478-1&Q13131-1.
TMPY-03878 Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His)

Integrin alpha V β6,ITGAV & ITGB6,integrin, alpha 5 (fibrone...

Human HEK293 Cells
Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 190.4 kDa and the accession number is P06756-1&P18564-1.
TMPY-02501 CD3D & CD3E Heterodimer Protein, Human, Recombinant

CD3d molecule, δ (CD3-TCR complex),CD3-δ,CD3d molecule, delt...

Human HEK293 Cells
CD3D & CD3E Heterodimer Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 77.5 kDa and the accession number is P04234-1&P07766-1.
TMPY-02030 CD82 Protein, Human, Recombinant (His)

CD82 molecule,SAR2,R2,KAI-1,4F9,KAI1,C33,T...

Human HEK293 Cells
CD82, also known as KAI-1, structurally belongs to tetraspanin family while categorised as metastasis suppressor gene on functional grounds. KAI1/CD82 is localized on cell membrane and form interactions with other tetraspanins, integrins and chemokines which are respectively responsible for cell migration, adhesion and signalling. Downregulation of CD82 expression is associated with the advanced stages of many human cancers and correlates with the acquisition of metastatic potential. Recent stud...
TMPY-01894 SIGIRR Protein, Human, Recombinant (His)

TIR8,single immunoglobulin and toll-interleukin 1 r...

Human HEK293 Cells
SIGIRR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14 kDa and the accession number is Q6IA17-1.
TMPY-01247 FLT3 Protein, Human, Recombinant (T227M, His)

FLK2,FLK-2,CD135,STK1,fms-related tyrosine...

Human HEK293 Cells
FLT3 Protein, Human, Recombinant (T227M, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.7 kDa and the accession number is P36888-1.
TMPY-02779 Thyroid peroxidase Protein, Human, Recombinant (S257A & P725T, His)

thyroid peroxidase,MSA,TPX,TDH2A

Human Baculovirus Insect Cells
Thyroid peroxidase is a membrane-bound glycoprotein which belongs to the peroxidase family, XPO subfamily. It contains 1 EGF-like domain and 1 Sushi (CCP/SCR) domain. Thyroid Peroxidase represents one of the main autoantigenic targets in autoimmune thyroid disease of humans. It used to be taken as the formerly so-called `microsomal antigen` several years ago. As an integral membrane glycoprotein it is restricted to the apical plasma membrane of the follicular epithelial cells and comprises two i...
TMPY-03290 HGF Protein, Mouse, Recombinant

hepatocyte growth factor (hepapoietin A,NK1,scatter...

Mouse HEK293 Cells
HGF Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 79.3 kDa and the accession number is Q08048-1.
TMPY-04970 TIGIT Protein, Human, Recombinant (hFc)

WUCAM,VSTM3,VSIG9,T cell immunoreceptor with Ig and ITIM dom...

Human HEK293 Cells
TIGIT Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 39.2 kDa and the accession number is Q495A1-1.
TMPY-01147 R-Spondin 1/RSPO1 Protein, Human, Recombinant (His)

RSPO,CRISTIN3,R-spondin 1

Human HEK293 Cells
R-Spondin 1/RSPO1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.2 kDa and the accession number is Q2MKA7-1.
TMPY-04346 PD-L2 Protein, Human, Recombinant (His)

PD-L2,B7-DC,CD273,Btdc,PDCD1L2,B7DC,PDL2,programmed...

Human HEK293 Cells
PD-L2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the accession number is Q9BQ51-1.
TMPY-00947 VCAM-1 Protein, Human, Recombinant (hFc)

INCAM-100,CD106,VCAM-1,vascular c...

Human HEK293 Cells
VCAM-1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 100.8 kDa and the accession number is P19320-1.
TMPY-01949 CD19 Protein, Human, Recombinant (His)

CD19 molecule,B4,CVID3

Human HEK293 Cells
CD19 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.6 kDa and the accession number is P15391-1.
TMPY-04165 FGFR3 Protein, Human, Recombinant (His)

JTK4,CEK2,fibroblast growth factor receptor 3,HSFGFR3EX,CD33...

Human HEK293 Cells
FGFR3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.6 kDa and the accession number is P22607-1.
TMPY-00820 IgG1 Fc Protein, Human, Recombinant (C103S)

Ighg1,IgG1 Fc

Human HEK293 Cells
IgG1 Fc Protein, Human, Recombinant (C103S) is expressed in HEK293 mammalian cells. The predicted molecular weight is 26 kDa and the accession number is P01857-1.
TMPY-01146 Insulin Receptor Protein, Human, Recombinant (long isoform, His)

HHF5,CD220,insulin receptor

Human HEK293 Cells
Insulin Receptor Protein, Human, Recombinant (long isoform, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 107 kDa and the accession number is P06213-1.
TMPY-04348 CTLA-4 Protein, Human, Recombinant (His)

ALPS5,CD152,GRD4,cytotoxic T-lymphocyte-associated ...

Human HEK293 Cells
CTLA-4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15 kDa and the accession number is P16410-1.
TMPY-02813 ErbB4 Protein, Human, Rhesus, Recombinant (His)

erb-b2 receptor tyrosine kinase 4

Human,Rhesus HEK293 Cells
ErbB4 Protein, Human, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 71.1 kDa and the accession number is Q15303-1.
TMPY-05220 TSLP Protein, Human, Recombinant (R127A & R130S, His)

thymic stromal lymphopoietin

Human HEK293 Cells
TSLP Protein, Human, Recombinant (R127A & R130S, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16.2 kDa and the accession number is Q969D9-1.
TMPY-01827 CD30/TNFRSF8 Protein, Human, Recombinant (His)

D1S166E,tumor necrosis factor receptor sup...

Human HEK293 Cells
CD30/TNFRSF8 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is P28908-1.
TMPY-00853 IL-1RA Protein, Human, Recombinant

DIRA,IL1RA,interleukin 1 receptor antagoni...

Human E. coli
IL-1RA Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.3 kDa and the accession number is P18510-1.
TMPY-01850 CEACAM3 Protein, Human, Recombinant (His)

W282,W264,CEA,CD66D,CGM1,MGC11987...

Human HEK293 Cells
CeACAM3 (CD66d), a member of carcinoembryonic antigen family, is a granulocyte-specific receptor involved in the opsonin-independent recognition of several bacterial pathogens. There are four members in this family: CD66a, CD66b, CD66c, and CD66d. Members of CEACAM family are widely expressed especially on human neutrophils, and, depending on the tissue, capable of regulating diverse functions including tumor promotion, tumor suppression, angiogenesis, and neutrophil activation. Abnormal overexp...
TMPY-02245 SNAP-25 Protein, Human, Recombinant (His)

synaptosomal-associated protein, 25kDa,SEC9,SNAP,RIC-4,dJ

Human E. coli
Synaptosomal-associated protein 25, also known as Super protein, Synaptosomal-associated 25 kDa protein, SNAP25 and SNAP, is a cytoplasm and cell membrane protein that belongs to the SNAP-25 family. SNAP25 / SUP contains 2 t-SNARE coiled-coil homology domains. SNAP25 / SUP is a membrane bound protein anchored to the cytosolic face of membranes via palmitoyl side chains in the middle of the molecule. SNAP25 / SUP protein is a component of the SNARE complex, which is proposed to account for the sp...
TMPY-00203 LOXL2 Protein, Mouse, Recombinant (His)

1110004B06Rik,4930526G1<...

Mouse HEK293 Cells
Lysyl oxidase homolog 2, also known as Lysyl oxidase-like protein 2, Lysyl oxidase-related protein 2, Lysyl oxidase-related protein WS9-14 and LOXL2, is a secreted protein that belongs to the lysyl oxidase family. LOXL2 contains four SRCR domains. The lysyl oxidase family is made up of five members: lysyl oxidase (LOX) and lysyl oxidase-like 1-4 ( LOXL1, LOXL2, LOXL3, LOXL4 ). All members share conserved C-terminal catalytic domains that provide for lysyl oxidase or lysyl oxidase-like enzyme act...
TMPY-01851 CD73 Protein, Human, Recombinant (His)

eN,NT5,E5NT,NT,5'-nucleotidase, ecto (CD73),NTE,CALJA,eNT,CD...

Human HEK293 Cells
CD73 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.2 kDa and the accession number is P21589-1.
TMPY-01281 ACVR2B Protein, Mouse, Recombinant (His)

ActRIIB,activin A receptor, type IIB,4930516B21...

Mouse HEK293 Cells
ACVR2B Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.8 kDa and the accession number is P27040-1.
TMPY-03967 BTN3A3 Protein, Human, Recombinant (His)

BTF3,BTN3.3,butyrophilin subfamily 3 member A3,BTN3A3

Human HEK293 Cells
BTN3A3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25 kDa and the accession number is O00478-1.
TMPY-02525 RGMA Protein, Human, Recombinant (His)

repulsive guidance molecule family member a,RGM

Human HEK293 Cells
RGMa, also known as RGM domain family, member A, belongs to the RGM (repulsive guidance molecule) family whose members are membrane-associated glycoprotein. RGMa is a glycosylphosphatidylinositol-anchored glycoprotein that functions as an axon guidance protein in the developing and adult central nervous system. It helps guide Retinal Ganglion Cell (RGC) axons to the tectum in the midbrain. RGMa has been implicated to play an important role in the developing brain and in the scar tissue that form...
TMPY-05208 PD-L1 Protein, Human, Recombinant

CD274 molecule,PDCD1L1,PD-L1,PDL<...

Human HEK293 Cells
PD-L1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 25.2 kDa and the accession number is Q9NZQ7-1.
TMPY-00978 Progranulin Protein, Human, Recombinant (His)

PGRN,PCDGF,CLN11,Granulin,GP88,GEP,Granuli...

Human HEK293 Cells
Progranulin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 63.2 kDa and the accession number is P28799-1.
TMPY-03407 NQO1 Protein, Human, Recombinant (His)

NAD(P)H dehydrogenase, quinone 1,NMORI,DIA4,QR1...

Human E. coli
NQO1 gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. NQO1 forms homodimers and reduces quinones to hydroquinones. NQO1's enzymatic activity prevents the one-electron reduction of quinones that results in the production of radical species. Mutations in the NQO1 gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered ex...
TMPY-01258 IL-13RA1 Protein, Human, Recombinant (His)

NR4,interleukin 13 receptor, alpha 1,CD2

Human HEK293 Cells
IL-13RA1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.3 kDa and the accession number is P78552-1.
TMPY-03531 PSGL-1/CD162 Protein, Human, Recombinant (His)

selectin P ligand,PSGL-1,PSGL1,CD1

Human HEK293 Cells
PSGL-1/CD162 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 30.5 kDa and the accession number is Q14242-1.
TMPY-01883 EPOR Protein, Human, Recombinant (His)

erythropoietin receptor,EPO-R

Human HEK293 Cells
EPOR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.3 kDa and the accession number is P19235-1.
TMPY-01862 IL-4 Protein, Human, Recombinant

Interleukin-4,IL-4,BCGF1,白细胞介素,interleukin 4,BSF

Human E. coli
IL-4 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 15.1 kDa and the accession number is P05112-1.
TMPY-06418 R-Spondin 2/RSPO2 Protein, Human, Recombinant (hFc)

R-spondin 2,CRISTIN2

Human HEK293 Cells
R-Spondin 2/RSPO2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48.01 kDa and the accession number is Q6UXX9-1.
TMPY-04333 LRRC15 Protein, Human, Recombinant (hFc)

leucine rich repeat containing 15,LIB

Human HEK293 Cells
LRRC15 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 84.5 kDa and the accession number is Q8TF66-1.
TMPY-02033 CD44 Protein, Human, Recombinant (His)

CD44 molecule (Indian blood group),IN,MC56,HUTCH-I,MIC4,CDW4...

Human HEK293 Cells
CD44 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 23.4 kDa and the accession number is P16070-1.
TMPY-04104 LIF Protein, Human, Recombinant

CDF,DIA,白血病抑制因子,MLPLI,Leukemia Inhibitory Factor,HILDA

Human HEK293 Cells
LIF Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 19.7 kDa and the accession number is P15018-1.
TMPY-04939 LAG-3 Protein, Human, Recombinant

LAG-3,lymphocyte-activation gene 3,CD223

Human HEK293 Cells
LAG-3 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 45.3 kDa and the accession number is P18627-1.
TMPY-00861 IL-33 Protein, Human, Recombinant

IL1F11,C9orf26,NFEHEV,NF-HEV,DVS2...

Human E. coli
IL-33 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 18 kDa and the accession number is O95760-1.
TMPY-06873 FLT3 Ligand Protein, Human, Recombinant

FLT3LG,fms related tyrosine kinase 3 ligand,FLT3L,FL

Human E. coli
FLT3 Ligand Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.75 kDa and the accession number is P49771-1.
TMPY-01185 DR5/TRAIL R2 Protein, Human, Recombinant (His)

KILLER,TRICK2A,TRICK2,DR5,TRICKB,tumor necrosis factor recep...

Human HEK293 Cells
DR5/TRAIL R2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.7 kDa and the accession number is O14763-1.
TMPY-01938 CD98 Protein, Human, Recombinant (His)

4T2HC,4F2,CD98HC,NACAE,MDU1,4F2HC,CD98,solute carri...

Human HEK293 Cells
CD98 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 49.2 kDa and the accession number is P08195-1.
TMPY-01137 HER2/ERBB2 Protein, Human, Recombinant (aa 1-652, His)

erb-b2 receptor tyrosine kinase 2,NEU,ENVW,HERV-7q,HERV7Q,HE...

Human HEK293 Cells
HER2/ERBB2 Protein, Human, Recombinant (aa 1-652, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 71 kDa and the accession number is P04626-1.
TMPY-04826 LILRB5/CD85c Protein, Human, Recombinant (His)

leukocyte immunoglobulin like receptor B5,LIR8,LIR-8,CD85C

Human HEK293 Cells
A genetic variant in LILRB5 (leukocyte immunoglobulin-like receptor subfamily-B) (rs12975366: T > C: Asp247Gly) has been reported to be associated with lower creatine phosphokinase (CK) and lactate dehydrogenase (LDH) levels. Both biomarkers are released from injured muscle tissue, making this variant a potential candidate for susceptibility to muscle-related symptoms. LILRB5/CD85c Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weig...
TMPY-01744 ACVR2A Protein, Human, Recombinant (His)

activin A receptor, type IIA,ACVR2,ACTRII

Human HEK293 Cells
ACVR2A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.9 kDa and the accession number is P27037-1.
TMPK-00887 KIR3DL2 Protein, Human, Recombinant (His & Avi)

KIR3DL2,p140,NKAT4,NKAT4A,NKAT4B,CL-5,CD15...

Human HEK293 Cells
KIR3DL2 is a member of the killer cell immunoglobulin-like receptor (KIR) family that was initially identified at the surface of natural killer (NK) cells. KIR3DL2, also known as CD158k, is expressed as a disulfide-linked homodimer. Each chain is composed of three immunoglobulin-like domains and a long cytoplasmic tail containing two immunoreceptor tyrosine-based inhibitory motifs. KIR3DL2 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The pred...
TMPY-00150 IGF2/IGF-II Protein, Human, Recombinant

PP9974,胰岛素样生长因子,C11orf43,IGF-II,insulin-li...

Human P. pastoris (Yeast)
Insulin-like growth factor 2 (IGF-2/IGF-II) is a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele, and epigenetic changes at this locus are associated with Wilms tumor, Beckwith-Wiedemann syndrome, rhabdomyosarcoma, and Silver-Russell syndrome. IGF-2/IGF-II is a mediator of prolactin-induced alveologenesis; prolactin, IGF-2, and cyclin D1, all of which are overexpressed in br...
TMPK-00383 ACE2/ACEH Protein, Human, Recombinant (His & Avi)

ACE2,ACE-2,ACEH

Human HEK293 Cells
ACE2 (Angiotensin I Converting Enzyme 2) is a Protein Coding gene. Diseases associated with ACE2 include Severe Acute Respiratory Syndrome and Neurogenic Hypertension.The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. A...
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重组蛋白

AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-04451
Species: Human
Expression System: Baculovirus Insect Cells
Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His)
Cat.No: TMPY-03878
Species: Human
Expression System: HEK293 Cells
CD3D & CD3E Heterodimer Protein, Human, Recombinant
Cat.No: TMPY-02501
Species: Human
Expression System: HEK293 Cells
CD82 Protein, Human, Recombinant (His)
Cat.No: TMPY-02030
Species: Human
Expression System: HEK293 Cells
SIGIRR Protein, Human, Recombinant (His)
Cat.No: TMPY-01894
Species: Human
Expression System: HEK293 Cells
FLT3 Protein, Human, Recombinant (T227M, His)
Cat.No: TMPY-01247
Species: Human
Expression System: HEK293 Cells
Thyroid peroxidase Protein, Human, Recombinant (S257A & P725T, His)
Cat.No: TMPY-02779
Species: Human
Expression System: Baculovirus Insect Cells
HGF Protein, Mouse, Recombinant
Cat.No: TMPY-03290
Species: Mouse
Expression System: HEK293 Cells
TIGIT Protein, Human, Recombinant (hFc)
Cat.No: TMPY-04970
Species: Human
Expression System: HEK293 Cells
R-Spondin 1/RSPO1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01147
Species: Human
Expression System: HEK293 Cells
PD-L2 Protein, Human, Recombinant (His)
Cat.No: TMPY-04346
Species: Human
Expression System: HEK293 Cells
VCAM-1 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00947
Species: Human
Expression System: HEK293 Cells
CD19 Protein, Human, Recombinant (His)
Cat.No: TMPY-01949
Species: Human
Expression System: HEK293 Cells
FGFR3 Protein, Human, Recombinant (His)
Cat.No: TMPY-04165
Species: Human
Expression System: HEK293 Cells
IgG1 Fc Protein, Human, Recombinant (C103S)
Cat.No: TMPY-00820
Species: Human
Expression System: HEK293 Cells
Insulin Receptor Protein, Human, Recombinant (long isoform, His)
Cat.No: TMPY-01146
Species: Human
Expression System: HEK293 Cells
CTLA-4 Protein, Human, Recombinant (His)
Cat.No: TMPY-04348
Species: Human
Expression System: HEK293 Cells
ErbB4 Protein, Human, Rhesus, Recombinant (His)
Cat.No: TMPY-02813
Species: Human,Rhesus
Expression System: HEK293 Cells
TSLP Protein, Human, Recombinant (R127A & R130S, His)
Cat.No: TMPY-05220
Species: Human
Expression System: HEK293 Cells
CD30/TNFRSF8 Protein, Human, Recombinant (His)
Cat.No: TMPY-01827
Species: Human
Expression System: HEK293 Cells
IL-1RA Protein, Human, Recombinant
Cat.No: TMPY-00853
Species: Human
Expression System: E. coli
CEACAM3 Protein, Human, Recombinant (His)
Cat.No: TMPY-01850
Species: Human
Expression System: HEK293 Cells
SNAP-25 Protein, Human, Recombinant (His)
Cat.No: TMPY-02245
Species: Human
Expression System: E. coli
LOXL2 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-00203
Species: Mouse
Expression System: HEK293 Cells
CD73 Protein, Human, Recombinant (His)
Cat.No: TMPY-01851
Species: Human
Expression System: HEK293 Cells
ACVR2B Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01281
Species: Mouse
Expression System: HEK293 Cells
BTN3A3 Protein, Human, Recombinant (His)
Cat.No: TMPY-03967
Species: Human
Expression System: HEK293 Cells
RGMA Protein, Human, Recombinant (His)
Cat.No: TMPY-02525
Species: Human
Expression System: HEK293 Cells
PD-L1 Protein, Human, Recombinant
Cat.No: TMPY-05208
Species: Human
Expression System: HEK293 Cells
Progranulin Protein, Human, Recombinant (His)
Cat.No: TMPY-00978
Species: Human
Expression System: HEK293 Cells
NQO1 Protein, Human, Recombinant (His)
Cat.No: TMPY-03407
Species: Human
Expression System: E. coli
IL-13RA1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01258
Species: Human
Expression System: HEK293 Cells
PSGL-1/CD162 Protein, Human, Recombinant (His)
Cat.No: TMPY-03531
Species: Human
Expression System: HEK293 Cells
EPOR Protein, Human, Recombinant (His)
Cat.No: TMPY-01883
Species: Human
Expression System: HEK293 Cells
IL-4 Protein, Human, Recombinant
Cat.No: TMPY-01862
Species: Human
Expression System: E. coli
R-Spondin 2/RSPO2 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-06418
Species: Human
Expression System: HEK293 Cells
LRRC15 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-04333
Species: Human
Expression System: HEK293 Cells
CD44 Protein, Human, Recombinant (His)
Cat.No: TMPY-02033
Species: Human
Expression System: HEK293 Cells
LIF Protein, Human, Recombinant
Cat.No: TMPY-04104
Species: Human
Expression System: HEK293 Cells
LAG-3 Protein, Human, Recombinant
Cat.No: TMPY-04939
Species: Human
Expression System: HEK293 Cells
IL-33 Protein, Human, Recombinant
Cat.No: TMPY-00861
Species: Human
Expression System: E. coli
FLT3 Ligand Protein, Human, Recombinant
Cat.No: TMPY-06873
Species: Human
Expression System: E. coli
DR5/TRAIL R2 Protein, Human, Recombinant (His)
Cat.No: TMPY-01185
Species: Human
Expression System: HEK293 Cells
CD98 Protein, Human, Recombinant (His)
Cat.No: TMPY-01938
Species: Human
Expression System: HEK293 Cells
HER2/ERBB2 Protein, Human, Recombinant (aa 1-652, His)
Cat.No: TMPY-01137
Species: Human
Expression System: HEK293 Cells
LILRB5/CD85c Protein, Human, Recombinant (His)
Cat.No: TMPY-04826
Species: Human
Expression System: HEK293 Cells
ACVR2A Protein, Human, Recombinant (His)
Cat.No: TMPY-01744
Species: Human
Expression System: HEK293 Cells
KIR3DL2 Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00887
Species: Human
Expression System: HEK293 Cells
IGF2/IGF-II Protein, Human, Recombinant
Cat.No: TMPY-00150
Species: Human
Expression System: P. pastoris (Yeast)
ACE2/ACEH Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00383
Species: Human
Expression System: HEK293 Cells
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Cat. No. Product Name Target Signaling Pathways
T14687 Deucravacitinib

BMS-986165

Tyrosine Kinases; JAK; IFNAR; Interleukin Angiogenesis; Chromatin/Epigenetic; Immunology/Inflammation; JAK/STAT signaling; Stem Cells; Tyrosine Kinase/Adaptors
Deucravacitinib (BMS-986165) 是一种高选择性、口服生物可利用的变构 TYK2 抑制剂,用于治疗自身免疫性疾病。它通过稳定调节 JH2 结构域来阻断受体介导的 Tyk2 激活,可抑制IL-12/23和 I 型IFN 途径。它选择性结合 TYK2 假激酶 (JH2) 结构域,IC50为1.0 nM。

同位素标记化合物

Deucravacitinib
Cat.No: T14687
Synonym: BMS-986165
Target: Tyrosine Kinases, JAK, IFNAR, Interleukin
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