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Search Results for " bmp2 "

6

抑制剂 & 化合物

11

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T82851	BMP2-derived peptide
	BMP2-derived peptide为BMP-2第73至92位氨基酸序列的功能性基序，具有促进骨髓基质细胞(BMSCs)成骨分化及骨再生的作用。
T1944	LDN-214117	ALK; TGF-beta/Smad	Angiogenesis; Stem Cells; Tyrosine Kinase/Adaptors
	LDN214117 是一种高效的 ALK2 选择性抑制剂(IC50:22nM)，也是一种 BMP6 抑制剂(IC50:100nM)，对ALK5抑制力弱100倍。
TP1345	Kisspeptin-10, human (TFA)(374675-21-5,FREE)	GPR; Kisspeptin	Endocrinology/Hormones; GPCR/G Protein
	Kisspeptin-10, human (TFA)(374675-21-5,FREE) 是一种有效的血管收缩剂和血管生成抑制剂。 Kisspeptin-10，人类 TFA 通过其受体 GPR54 充当肿瘤转移抑制因子。 Kisspeptin-10-GPR54系统在胚胎肾发育中发挥重要作用。 Kisspeptin-10/GPR54 信号通过 NFATc4 介导的 BMP2 表达诱导成骨细胞分化
T23840	BUR1 BMP upregulator-1,1-{1-苯基-1H-吡唑并[3,4-D]嘧啶-4-基}哌啶,BMP upregulator 1,BUR 1,BUR-1	CDK	Cell Cycle/Checkpoint
	BUR1 是一种酿酒酵母细胞周期蛋白依赖性激酶 (CDK)，与在转录延伸中起作用的哺乳动物 Cdk9 同源。
T69974	Phenamil	Others	Others
	Phenamil is an irreversible inhibitor of amiloride-sensitive Na channels; derivative of amiloride, synergizing bone formation with BMP2 and inhibits BMP2 induced cyst-like bone formation.
T75745	Kisspeptin-10, human TFA
	Kisspeptin-10, human TFA为一种有效的血管收缩剂及血管生成抑制剂，通过其受体GPR54抑制肿瘤转移。Kisspeptin-10-GPR54系统对胚胎肾脏发展具有关键影响，而Kisspeptin-10/GPR54信号则通过NFATc4介导的BMP2表达促进成骨细胞分化。

化合物

BMP2-derived peptide

Cat.No: T82851

Cat.No: T1944

Target: ALK, TGF-beta/Smad

Kisspeptin-10, human (TFA)(374675-21-5,FREE)

Cat.No: TP1345

Target: GPR, Kisspeptin

Cat.No: T23840

Synonym: BMP upregulator-1,1-{1-苯基-1H-吡唑并[3,4-D]嘧啶-4-基}哌啶,BMP upregulator 1,BUR 1,BUR-1

Target: CDK

Cat.No: T69974

Target: Others

Kisspeptin-10, human TFA

Cat.No: T75745

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-02311	WDR5 Protein, Human, Recombinant (His & SUMO) WDR5,BMP2-induced 3-kb gene protein,WD rep...	Human	E. coli
	WDR5 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 52.5 kDa and the accession number is P61964.
TMPH-01014	BMP-2 Protein, Human, Recombinant (His) BMP-2,Bone morphogenetic protein 2	Human	E. coli
	BMP-2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 16.9 kDa and the accession number is P12643.
TMPY-00680	BMP-2 Protein, Human, Mouse, Rat, Rhesus, Canine, Recombinant (hFc) bone morphogenetic protein 2	Human,Mouse,Rat,Rhesus,Canine	HEK293 Cells
	BMP-2 Protein, Human, Mouse, Rat, Rhesus, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 39.5 kDa and the accession number is C8C060.
TMPY-03297	BMP-2 Protein, Danio rerio (zebrafish), Recombinant bone morphogenetic protein 2	Danio rerio (zebrafish)	E. coli
	BMP-2 Protein, Danio rerio (zebrafish), Recombinant is expressed in E. coli expression system. The predicted molecular weight is 13.2 kDa and the accession number is B3DI86.
TMPY-01136	BMP-2 Protein, Human, Mouse, Rat, Rhesus, Canine, Recombinant bone morphogenetic protein 2	Human,Mouse,Rat,Rhesus,Canine	E. coli
	BMP-2 Protein, Human, Mouse, Rat, Rhesus, Canine, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 13 kDa and the accession number is C8C060.
TMPH-02885	SOSTDC1 Protein, Mouse, Recombinant (His & Myc) Sclerostin-like protein,Sostdc1,Sclerostin domain-containing...	Mouse	E. coli
	May be involved in the onset of endometrial receptivity for implantation/sensitization for the decidual cell reaction. Enhances Wnt signaling and inhibits TGF-beta signaling. Directly antagonizes activity of BMP2, BMP4, BMP6 and BMP7 in a dose-dependent manner.
TMPH-03367	SOSTDC1 Protein, Rat, Recombinant (His & Myc) Sostdc1,Sclerostin domain-containing protein 1,Wnt-signaling...	Rat	HEK293 Cells
	Directly antagonizes activity of BMP2, BMP4, BMP6 and BMP7 in a dose-dependent manner. May be involved in the onset of endometrial receptivity for implantation/sensitization for the decidual cell reaction. Enhances Wnt signaling and inhibits TGF-beta signaling. SOSTDC1 Protein, Rat, Recombinant (His & Myc) is expressed in HEK293 mammalian cells with N-10xHis and C-Myc tag. The predicted molecular weight is 24.6 kDa and the accession number is Q642G2.
TMPH-02240	TMEM119 Protein, Human, Recombinant (hFc) Osteoblast induction factor,TMEM119,Transmembrane protein 11...	Human	HEK293 Cells
	Plays an important role in bone formation and normal bone mineralization. Promotes the differentiation of myoblasts into osteoblasts. May induce the commitment and differentiation of myoblasts into osteoblasts through an enhancement of BMP2 production and interaction with the BMP-RUNX2 pathway. Upregulates the expression of ATF4, a transcription factor which plays a central role in osteoblast differentiation. Essential for normal spermatogenesis and late testicular differentiation.
TMPH-02579	CHRDL1 Protein, Mouse, Recombinant (His & Myc) Nrln1,Neuralin-1,Ng1,Neurogenesin-1,Chrdl1,Ventroptin,Chordi...	Mouse	Baculovirus Insect Cells
	Seems to antagonize the function of BMP4 by binding to it and preventing its interaction with receptors. Alters the fate commitment of neural stem cells from gliogenesis to neurogenesis. Contributes to neuronal differentiation of neural stem cells in the brain by preventing the adoption of a glial fate. May play a crucial role in dorsoventral axis formation. Antagonizes the function of BMP7 and may thus play an important role in the embryonic bone formation. Shows no inhibitory effect on the ind...
TMPY-00975	FSTL3 Protein, Mouse, Recombinant (His) E030038F23Rik,Flrg,follistatin-like 3 (secreted gly...	Mouse	HEK293 Cells
	Follistatin-like 3 (FLRG/Fstl3) is a secreted glycoprotein of the follistatin-module-protein family. It may have a role in leukemogenesis. FLRG/Fstl3 is a recently described member of the FST family having an overall structure and activity profile similar to that of FST, including binding and neutralization of activin. FLRG/Fstl3 is expressed in a wide range of adult tissues, not detected in hematopoietic cells except in patients with a B cell chronic leukemia and a translocation. Isoform 1 or t...
TMPY-01755	VWC2 Protein, Human, Recombinant (His) PSST739,von Willebrand factor C domain containing 2...	Human	HEK293 Cells
	Brorin, also known as brain-specific chordin-like protein, von Willebrand factor C domain-containing protein 2 and VWC2, is a secreted protein that contains two VWFC domains. VWC2 / Brorin is a BMP antagonist that may play a role in neural development. It promotes cell adhesion. VWC2 / Brorin is a unique member of the chordin family. It inhibited the activity of bone morphogenetic protein 2 (BMP2) and BMP6 in mouse preosteoblastic MC3T3-E1 cells. Mouse Brorin was predominantly expressed in neura...

重组蛋白

WDR5 Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-02311

Species: Human

Expression System: E. coli

BMP-2 Protein, Human, Recombinant (His)

Cat.No: TMPH-01014

Species: Human

Expression System: E. coli

BMP-2 Protein, Human, Mouse, Rat, Rhesus, Canine, Recombinant (hFc)

Cat.No: TMPY-00680

Species: Human,Mouse,Rat,Rhesus,Canine

Expression System: HEK293 Cells

BMP-2 Protein, Danio rerio (zebrafish), Recombinant

Cat.No: TMPY-03297

Species: Danio rerio (zebrafish)

Expression System: E. coli

BMP-2 Protein, Human, Mouse, Rat, Rhesus, Canine, Recombinant

Cat.No: TMPY-01136

Species: Human,Mouse,Rat,Rhesus,Canine

Expression System: E. coli

SOSTDC1 Protein, Mouse, Recombinant (His & Myc)

Cat.No: TMPH-02885

Species: Mouse

Expression System: E. coli

SOSTDC1 Protein, Rat, Recombinant (His & Myc)

Cat.No: TMPH-03367

Species: Rat

Expression System: HEK293 Cells

TMEM119 Protein, Human, Recombinant (hFc)

Cat.No: TMPH-02240

Species: Human

Expression System: HEK293 Cells

CHRDL1 Protein, Mouse, Recombinant (His & Myc)

Cat.No: TMPH-02579

Species: Mouse

Expression System: Baculovirus Insect Cells

FSTL3 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-00975

Species: Mouse

Expression System: HEK293 Cells

VWC2 Protein, Human, Recombinant (His)

Cat.No: TMPY-01755

Species: Human

Expression System: HEK293 Cells

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