|
TMPY-00484
|
Cerberus 1/CER1 Protein, Human, Recombinant (His)
DAND4,cerberus 1, DAN family BMP antagonist
|
Human
|
Baculovirus Insect Cells
|
|
Cerberus 1/CER1 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 29.6 kDa and the accession number is AAH69371.1. |
|
TMPH-01015
|
BMP-3 Protein, Human, Recombinant (His)
BMP3A,Bone morphogenetic protein 3A,BMP3,O...
|
Human
|
E. coli
|
|
Growth factor of the TGF-beta superfamily that plays an essential role in developmental process by inducing and patterning early skeletal formation and by negatively regulating bone density. Antagonizes the ability of certain osteogenic BMPs to induce osteoprogenitor differentitation and ossification. Initiates signaling cascades by associating with type II receptor ACVR2B to activate SMAD2-dependent and SMAD-independent signaling cascades including TAK1 and JNK pathways. BMP-3 Protein, Human, R... |
|
TMPH-01014
|
BMP-2 Protein, Human, Recombinant (His)
BMP-2,Bone morphogenetic protein 2A,BMP2,<...
|
Human
|
E. coli
|
|
BMP-2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 16.9 kDa and the accession number is P12643. |
|
TMPH-01017
|
BMP-4 Protein, Human, Recombinant (His)
BMP4,Bone morphogenetic protein 4,BMP-4
|
Human
|
E. coli
|
|
BMP-4 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 15.4 kDa and the accession number is P12644. |
|
TMPH-00228
|
BMP-4 Protein, Bovine, Recombinant (GST)
Bone morphogenetic protein 4,BMP4,BMP-4
|
Bovine
|
E. coli
|
|
BMP-4 Protein, Bovine, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 40.6 kDa and the accession number is Q2KJH1. |
|
TMPY-00431
|
BMP-4 Protein, Mouse, Recombinant (rFc)
bone morphogenetic protein 4,Bmp-4,Bmp2b-1...
|
Mouse
|
HEK293 Cells
|
|
BMP-4 Protein, Mouse, Recombinant (rFc) is expressed in HEK293 mammalian cells with rFc tag. The predicted molecular weight is 40.6 kDa and the accession number is P21275. |
|
TMPY-06842
|
BMP-4 Protein, Human, Recombinant (E399D)
OFC11,BMP2B,bone morphogenetic protein 4,BMP
|
Human
|
E. coli
|
|
BMP-4 Protein, Human, Recombinant (E399D) is expressed in E. coli expression system. The predicted molecular weight is 13.25 kDa and the accession number is P12644. |
|
TMPH-01019
|
BMP-7 Protein, Human, Recombinant (GST)
BMP-7,OP1,BMP7,OP-1,Bone morphogenetic pro...
|
Human
|
E. coli
|
|
BMP-7 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 42.7 kDa and the accession number is P18075. |
|
TMPH-01012
|
BMP-1 Protein, Human, Recombinant (His)
PCOLC,mTld,Procollagen C-proteinase,Mammalian tolloid protei...
|
Human
|
E. coli
|
|
BMP-1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 102.0 kDa and the accession number is P13497. |
|
TMPH-01018
|
BMP-6 Protein, Human, Recombinant (His)
BMP-6,BMP6,VG-1-R,VGR,VG-1-related protein...
|
Human
|
E. coli
|
|
BMP-6 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 18.9 kDa and the accession number is P22004. |
|
TMPH-01013
|
BMP-15 Protein, Human, Recombinant (His & Myc)
BMP15,GDF-9B,BMP-15,Bone morphogenetic pro...
|
Human
|
E. coli
|
|
May be involved in follicular development. Oocyte-specific growth/differentiation factor that stimulates folliculogenesis and granulosa cell (GC) growth. BMP-15 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 21.4 kDa and the accession number is O95972. |
|
TMPY-00680
|
BMP-2 Protein, Human, Mouse, Rat, Rhesus, Canine, Recombinant (hFc)
bone morphogenetic protein 2
|
Human,Mouse,Rat,Rhesus,Canine
|
HEK293 Cells
|
|
BMP-2 Protein, Human, Mouse, Rat, Rhesus, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 39.5 kDa and the accession number is C8C060. |
|
TMPH-02552
|
BMP3 Protein, Mouse, Recombinant (Myc)
Bone morphogenetic protein 3,Bmp3,BMP-3
|
Mouse
|
E. coli
|
|
Negatively regulates bone density. Antagonizes the ability of certain osteogenic BMPs to induce osteoprogenitor differentitation and ossification. |
|
TMPY-03127
|
BAMBI Protein, Mouse, Recombinant (hFc)
2610003H06Rik,BMP and activin membrane-bound inhibi...
|
Mouse
|
HEK293 Cells
|
|
BAMBI Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 41 kDa and the accession number is Q9D0L6. |
|
TMPY-01456
|
BAMBI Protein, Human, Recombinant (His)
BMP and activin membrane-bound inhibitor,NMA
|
Human
|
HEK293 Cells
|
|
BAMBI Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16.1 kDa and the accession number is Q13145. |
|
TMPY-04334
|
BAMBI Protein, Mouse, Recombinant (His)
BMP and activin membrane-bound inhibitor,2610003H06...
|
Mouse
|
HEK293 Cells
|
|
BAMBI Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.4 kDa and the accession number is Q9D0L6. |
|
TMPJ-01473
|
BMP-7 Protein, Human, Recombinant
Eptotermin alfa,OP-1,OP1,Osteogenic protein 1,Bone morphogen...
|
Human
|
HEK293 Cells
|
|
Bone morphogenetic protein 7 (BMP7), also known as osteogenic protein-1 (OP-1) is a member of Transforming growth factor-β (TGF-β) family of proteins. Bone morphogenetic proteins were discovered in 1965 by Marshal Urist, of which BMP7 is of particular interest in this review being a leptin-independent anorexinogen and having role in energy expenditure in the brown adipose tissue, which makes it a potential target for preventing/treating obesity. As it has been established that Obesity displays a... |
|
TMPY-00681
|
BMP-5 Protein, Human, Recombinant (hFc)
bone morphogenetic protein 5
|
Human
|
HEK293 Cells
|
|
Bone Morphogenetic Protein 5 (BMP-5) is a member of the structurally and functionally related bone morphogenetic proteins (BMPs) which constitute a novel subfamily of the transforming growth factor β (TGF-β) superfamily. In agreement with a possible role in the control of cell death, BMP-5 exhibited a regulated pattern of expression in the interdigital tissue. Transcripts of BMP-5 and BMP-5 protein were abundant within the cytoplasm of the fragmenting apoptotic interdigital cells in a way sugges... |
|
TMPJ-00713
|
GDF-11 Protein, Human, Recombinant
Growth/differentiation factor 11,Bone morphogenetic protein ...
|
Human
|
HEK293 Cells
|
|
Growth/differentiation factor 11(GDF-11) is a secreted protein, which belongs to the transforming growth factor beta superfamily. GDF-11 controls anterior-posterior patterning by regulating the expression of Hox genes. The secreted signal acts globally to specify positional identity along the anterior/posterior axis during development. GDF11 has been shown to suppress neurogenesis through a pathway similar to that of myostatin, including stopping the progenitor cell-cycle during G-phase. The si... |
|
TMPY-02670
|
NBL1 Protein, Mouse, Recombinant (His)
neuroblastoma 1, DAN family BMP antagonist,DAN,NO3,...
|
Mouse
|
HEK293 Cells
|
|
NBL1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 18.8 kDa and the accession number is Q61477. |
|
TMPY-00771
|
NBL1 Protein, Human, Recombinant (hFc)
neuroblastoma 1, DAN family BMP antagonist,NO3,NB,D...
|
Human
|
HEK293 Cells
|
|
NBL1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 44.4 kDa and the accession number is P41271-1. |
|
TMPY-01039
|
NBL1 Protein, Human, Recombinant (His)
neuroblastoma 1, DAN family BMP antagonist,NO3,DAN,...
|
Human
|
HEK293 Cells
|
|
NBL1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 19.3 kDa and the accession number is P41271-1. |
|
TMPY-03297
|
BMP-2 Protein, Danio rerio (zebrafish), Recombinant
bone morphogenetic protein 2
|
Danio rerio (zebrafish)
|
E. coli
|
|
BMP-2 Protein, Danio rerio (zebrafish), Recombinant is expressed in E. coli expression system. The predicted molecular weight is 13.2 kDa and the accession number is B3DI86. |
|
TMPY-01136
|
BMP-2 Protein, Human, Mouse, Rat, Rhesus, Canine, Recombinant
bone morphogenetic protein 2
|
Human,Mouse,Rat,Rhesus,Canine
|
E. coli
|
|
BMP-2 Protein, Human, Mouse, Rat, Rhesus, Canine, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 13 kDa and the accession number is C8C060. |
|
TMPH-03308
|
Gremlin-1 Protein, Rat, Recombinant (His & Myc)
Down-regulated in Mos-transformed cells protein,Gremlin-1,Cy...
|
Rat
|
HEK293 Cells
|
|
Gremlin-1 Protein, Rat, Recombinant (His & Myc) is expressed in HEK293. |
|
TMPH-02885
|
SOSTDC1 Protein, Mouse, Recombinant (His & Myc)
Sclerostin-like protein,Sostdc1,Sclerostin domain-containing...
|
Mouse
|
E. coli
|
|
May be involved in the onset of endometrial receptivity for implantation/sensitization for the decidual cell reaction. Enhances Wnt signaling and inhibits TGF-beta signaling. Directly antagonizes activity of BMP2, BMP4, BMP6 and BMP7 in a dose-dependent manner. |
|
TMPH-02748
|
KCP Protein, Mouse, Recombinant (His & Myc)
Kcp,Cysteine-rich BMP regulator 2,Kielin/chordin-li...
|
Mouse
|
E. coli
|
|
Enhances bone morphogenetic protein (BMP) signaling in a paracrine manner. In contrast, it inhibits both the activin-A and TGFB1-mediated signaling pathways. KCP Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 44.7 kDa and the accession number is Q3U492. |
|
TMPH-01079
|
CLN5 Protein, Human, Recombinant (His)
CLN5,BMPS,Bis(monoacylglycero)phosphate synthase CL...
|
Human
|
E. coli
|
|
Plays a role in influencing the retrograde trafficking of lysosomal sorting receptors SORT1 and IGF2R from the endosomes to the trans-Golgi network by controlling the recruitment of retromer complex to the endosomal membrane. Regulates the localization and activation of RAB7A which is required to recruit the retromer complex to the endosomal membrane. CLN5 Protein, Human, Recombinant (His) is expressed in E. coli expression system with C-6xHis tag. The predicted molecular weight is 43.5 kDa and ... |
|
TMPJ-00966
|
GDF-5 Protein, Human, Recombinant
Lipopolysaccharide-associated protein 4,Cartilage-derived mo...
|
Human
|
E. coli
|
|
Growth Differentiation Factor 5(GDF-5, BMP-14) is a member of the BMP family of TGFβ superfamily proteins. Human GDF-5, -6, and -7 are a defined subgroup of the BMP family. GDF-5 is synthesized as a homodimeric precursor protein consisting of a 354 amino acid (aa) Nterminal proregion and a 120 aa C-terminal mature peptide. Mature human GDF-5 shares 99% aa sequence identity with both mature mouse and rat GDF-5. GDF-5 signaling is mediated by formation of a heterodimeric complex consisting of a ty... |
|
TMPJ-00325
|
BMPR1A/ALK-3 Protein, Human, Recombinant (hFc & His)
BMP Type-1A Receptor,Bone Morphogenetic Protein Rec...
|
Human
|
HEK293 Cells
|
|
Bone Morphogenetic Protein Receptor Type-1A (BMPR1A) belongs to the TKL Ser/Thr protein kinase family and TGFB receptor subfamily, including the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. BMPR1A is a single-pass type I membrane protein and highly expressed in skeletal muscle. BMPR1A contains one GS domain and one protein protein kinase domain. BMPR1A is necessary for the extracellular matrix depostition by osteoblasts. BMPR1A can activate SMAD transcriptional regulators, ... |
|
TMPY-01059
|
BMPR2 Protein, Human, Recombinant (His)
POVD1,PPH1,BMPR3,BRK-3,BMPR-II,bone morpho...
|
Human
|
HEK293 Cells
|
|
BMPR2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.6 kDa and the accession number is Q13873. |
|
TMPY-01374
|
BMPR1A/ALK-3 Protein, Mouse, Recombinant (His)
ALK3,BMPR-IA,bone morphogenetic protein receptor, t...
|
Mouse
|
HEK293 Cells
|
|
BMPR1A/ALK-3 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.8 kDa and the accession number is P36895. |
|
TMPY-05485
|
BMPR1A/ALK-3 Protein, Human, Recombinant (hFc)
ACVRLK3,SKR5,10q23del,CD292,bone morphogenetic protein recep...
|
Human
|
HEK293 Cells
|
|
BMPR1A/ALK-3 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 40.9 kDa and the accession number is P36894. |
|
TMPJ-00476
|
BMPG Protein, Human, Recombinant (His)
Bone Marrow Proteoglycan,PRG2,Proteoglycan 2,Eosinophil Gran...
|
Human
|
HEK293 Cells
|
|
Bone Marrow Proteoglycan (BMPG) is a secreted protein that contains one C-type lectin domain. BMPG is the predominant constituent of the crystalline core of the eosinophil granule. BMPG is highly expressed in placenta and pregnancy serum. BMPG may be involved in antiparasitic defense mechanisms as a cytotoxin and helminthotoxin. BMPG induces non-cytolytic histamine release from human basophils. In addition, BMPG also participated in antiparasitic defense mechanisms and immune hypersensitivity re... |
|
TMPY-04496
|
BMPRIB Protein, Mouse, Recombinant (hFc)
Alk6,ALK-6,CFK-43a,BMPR-1B,SKR6,BMPR-IB,bo...
|
Mouse
|
HEK293 Cells
|
|
BMPRIB Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 39.4 kDa and the accession number is B2RRZ4. |
|
TMPY-01764
|
BMPR1A/ALK-3 Protein, Human, Recombinant (His)
bone morphogenetic protein receptor, type IA,ALK3,ACVRLK3,10...
|
Human
|
HEK293 Cells
|
|
BMPR1A/ALK-3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.7 kDa and the accession number is P36894. |
|
TMPY-00683
|
BMPR2 Protein, Human, Recombinant (His & hFc)
BMPR3,BRK-3,PPH1,BMPR-II,bone morphogeneti...
|
Human
|
HEK293 Cells
|
|
BMPR2 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 42 kDa and the accession number is Q13873. |
|
TMPY-00962
|
BMPR1A/ALK-3 Protein, Mouse, Recombinant (His & hFc)
Bmpr,bone morphogenetic protein receptor, type IA,<...
|
Mouse
|
HEK293 Cells
|
|
BMPR1A/ALK-3 Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 42 kDa and the accession number is P36895. |
|
TMPY-03362
|
BMPRIB Protein, Human, Recombinant (hFc)
ALK6,bone morphogenetic protein receptor, type IB,CDw293,ALK...
|
Human
|
HEK293 Cells
|
|
BMPRIB Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 39.7 kDa and the accession number is O00238-1. |
|
TMPY-04367
|
BMPRIB Protein, Human, Recombinant (aa 149-502, His & GST)
bone morphogenetic protein receptor, type IB,CDw293,ALK-6,AL...
|
Human
|
Baculovirus Insect Cells
|
|
BMPRIB Protein, Human, Recombinant (aa 149-502, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 68.3 kDa and the accession number is O00238-1. |
|
TMPY-00614
|
BMPR1A/ALK-3 Protein, Canine, Recombinant (hFc)
bone morphogenetic protein receptor, type IA
|
Canine
|
HEK293 Cells
|
|
BMPR1A/ALK-3 Protein, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 41.2 kDa and the accession number is A0A8C0S7K5. |
|
TMPK-00925
|
Noggin/NOG Protein, Mouse, Recombinant
NOG,SYM1,SYNS1,Noggin
|
Mouse
|
HEK293 Cells
|
|
Noggin is an antagonist of bone morphogenetic proteins (BMP), being indispensable for certain developmental events.Noggin expression positively correlated with EGFR expression in both GC cell line models and The Cancer Genome Atlas human GC cohort. Targeting EGFR and its downstream pathways diminished cell proliferation which was promoted by Noggin. Noggin promotes the proliferation of GC cells by upregulating EGFR and enhancing a vicious circle formed by β‑catenin, EGFR, ERK and Akt. Noggin/NOG... |
|
TMPJ-01065
|
Noggin/NOG Protein, Mouse, Recombinant (His)
Nog,Noggin
|
Mouse
|
HEK293 Cells
|
|
Noggin is a secreted homodimeric glycoprotein that is an antagonist of bone morphogenetic proteins (BMPs). Mouse Noggin cDNA encodes a 232 amino acid (aa) residue precursor protein with 19 aa residue putative signal peptide that is cleaved to generate the 213 aa residue mature protein which is secreted as a homodimeric glycoprotein. Secreted Noggin probably remains close to the cell surface due to its binding of heparin-containing proteoglycans. Noggin binds some BMPs such as BMP4 with high affi... |
|
TMPK-01152
|
CHRDL1 Protein, Human, Recombinant (His)
VOPT,Ventroptin,Neuralin-1,dA141H5.1,CHL,Chordin-like 1,CRDL...
|
Human
|
E. coli
|
|
CHRDL1 (Chordin-like 1) is a secreted protein that acts as an antagonist of bone morphogenetic protein (BMP). BMP plays a role as an activator of BMP receptor II (BMPR II), which mediates extracellular to intracellular signal transmission and is involved in carcinogenesis and metastasis.The hypermethylation of the CHRDL1 promoter in gastric cancer, which induced low expression of CHRDL1 and decreased its secretion to the supernatant. |
|
TMPJ-01322
|
TWSG1 Protein, Human, Recombinant (His)
TSG,Twisted Gastrulation Protein Homolog 1,TWSG1
|
Human
|
HEK293 Cells
|
|
Twisted Gastrulation Protein Homolog 1 (TWSG1) is a 22 kDa secreted protein that belongs to the twisted gastrulation protein family. Human TWSG1 is synthesized as a 223 aa precursor that contains a 25 aa signal peptide and a 198 aa mature chain. TWSG1 may be involved in dorsoventral axis formation. TWSG1 seems to antagonize BMP signaling by forming ternary complexes with CHRD and BMPs, thereby preventing BMPs from binding to their receptors.TWSG1 can inhibit BMP activity by binding directly to B... |
|
TMPJ-01294
|
SOST Protein, Mouse, Recombinant (His)
Sost,Sclerostin
|
Mouse
|
HEK293 Cells
|
|
Sclerostin (SOST) is a member of the cerberus/DAN family, a group of secreted glycoproteins characterized by a cysteine-knot
motif. Cerberus/DAN
family members are putative BMP antagonists, and include Dan, Cerberus, Gremlin, PRDC, and Caronte. While the overall sequence identity between members of the family is low, they have conserved spacing of six cysteine residues. Cerberus and Dan have an additional cysteine residue used for dimerization; however, SOST does not and is secreted as a monomer... |
|
TMPH-02213
|
Tomoregulin-1 Protein, Human, Recombinant (E. coli, His)
H7365,TMEFF1,Tomoregulin-1,Transmembrane protein with EGF-li...
|
Human
|
E. coli
|
|
May inhibit NODAL and BMP signaling during neural patterning. May be a tumor suppressor in brain cancers. |
|
TMPY-01817
|
GDF-10 Protein, Mouse, Recombinant (hFc)
growth differentiation factor 10,Bmp3b
|
Mouse
|
HEK293 Cells
|
|
BMP-3b / GDF-10 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in mice suggest that the protein encoded by this gene plays a role in skeletal morphogenesis. In th... |
|
TMPH-01702
|
SMAD6 Protein, Human, Recombinant (E. coli, His & Myc)
SMAD6,Mothers against decapentaplegic homolog 6,SMAD family ...
|
Human
|
E. coli
|
|
Transforming growth factor-beta superfamily receptors signaling occurs through the Smad family of intracellular mediators. SMAD6 is an inhibitory Smad (i-Smad) that negatively regulates signaling downstream of type I transforming growth factor-beta. Acts as a mediator of TGF-beta and BMP anti-inflammatory activities. Suppresses IL1R-TLR signaling through its direct interaction with PEL1, preventing NF-kappa-B activation, nuclear transport and NF-kappa-B-mediated expression of proinflammatory gen... |
|
TMPY-01755
|
VWC2 Protein, Human, Recombinant (His)
PSST739,von Willebrand factor C domain containing 2,UNQ739
|
Human
|
HEK293 Cells
|
|
Brorin, also known as brain-specific chordin-like protein, von Willebrand factor C domain-containing protein 2 and VWC2, is a secreted protein that contains two VWFC domains. VWC2 / Brorin is a BMP antagonist that may play a role in neural development. It promotes cell adhesion. VWC2 / Brorin is a unique member of the chordin family. It inhibited the activity of bone morphogenetic protein 2 (BMP2) and BMP6 in mouse preosteoblastic MC3T3-E1 cells. Mouse Brorin was predominantly expressed in neura... |
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