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Search Results for " bm cells "

Targets Recommended: PPAR

2

抑制剂 & 化合物

1

天然产物

11

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T15049	Daltroban BM-13505,SKF 96148	PPAR	DNA Damage/DNA Repair; Metabolism
	Daltroban (SKF 96148) (BM-13505) 是选择性和特异性的血栓素 A2 (TXA2) 受体拮抗剂。Daltroban 可以增加血管平滑肌细胞内钙。Daltroban 显示对再灌注损伤的保护作用。
T36539	Nocardamine	Others	Others
	Nocardamine is a ferrioxamine siderophore that has been found inStreptomycesand has diverse biological activities.1,2,3,4It chelates iron in a chrome azurol S assay (IC50= 9.9 μM).1Nocardamine inhibitsM. smegmatisandM. bovisbiofilm formation (MIC = 10 μM for both), an effect that can be reversed by iron.2It is cytotoxic to T47D, SK-MEL-5, SK-MEL-28, and RPMI-7951 cancer cells (IC50s = 6, 18, 12, and 14 μM, respectively).3Nocardamine also induces morphological changes in BM-N4 insect cells.4 1.Lo...

化合物

Cat.No: T15049

Synonym: BM-13505,SKF 96148

Target: PPAR

Cat.No: T36539

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T0480	Doxofylline Doxophylline,多索茶碱	PDE; Adenosine Receptor	GPCR/G Protein; Metabolism; Neuroscience
	Doxofylline (Doxophylline) 是腺苷 A1 受体拮抗剂，且能抑制磷酸二酯酶 IV，用于治疗哮喘。

天然产物

Cat.No: T0480

Synonym: Doxophylline,多索茶碱

Target: PDE, Adenosine Receptor

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPK-00340	ALCAM Protein, Human, Recombinant (His & Avi), Biotinylated CD166,CD6L,KG-CAM,ALCAM,MEMD	Human	HEK293 Cells
	Brain metastasis (BM) in non-small-cell lung cancer (NSCLC) has a very poor prognosis. Recent studies have demonstrated the importance of cell adhesion molecules in tumor metastasis.Elevated levels of ALCAM expression promote BM formation in NSCLC through increased tumor cell dissemination and interaction with the brain endothelial cells. Therefore, ALCAM could be targeted to reduce the occurrence of BM. ALCAM Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian...
TMPK-00339	ALCAM Protein, Mouse, Recombinant (His & Avi), Biotinylated CD6L,ALCAM,MEMD,KG-CAM,CD166	Mouse	HEK293 Cells
	Brain metastasis (BM) in non-small-cell lung cancer (NSCLC) has a very poor prognosis. Recent studies have demonstrated the importance of cell adhesion molecules in tumor metastasis.Elevated levels of ALCAM expression promote BM formation in NSCLC through increased tumor cell dissemination and interaction with the brain endothelial cells. Therefore, ALCAM could be targeted to reduce the occurrence of BM. ALCAM Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian...
TMPK-00341	ALCAM Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated ALCAM,KG-CAM,MEMD,CD166,CD6L	Human	HEK293 Cells
	Brain metastasis (BM) in non-small-cell lung cancer (NSCLC) has a very poor prognosis. Recent studies have demonstrated the importance of cell adhesion molecules in tumor metastasis.Elevated levels of ALCAM expression promote BM formation in NSCLC through increased tumor cell dissemination and interaction with the brain endothelial cells. Therefore, ALCAM could be targeted to reduce the occurrence of BM. ALCAM Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated is expressed ...
TMPY-06618	SARS-CoV-2 BM.1.1.1 (Omicron) Spike RBD Protein (His)	SARS-CoV-2	HEK293 Cells
	SARS-CoV-2 BM.1.1.1 (Omicron) Spike RBD Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.57 kDa and the accession number is YP_009724390.1.
TMPY-06633	SARS-CoV-2 BM.1.1.1 (Omicron) Spike S1+S2 trimer Protein (His)	SARS-CoV-2	HEK293 Cells
	SARS-CoV-2 BM.1.1.1 (Omicron) Spike S1+S2 trimer Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 136.35 kDa and the accession number is YP_009724390.1.
TMPK-00357	CD229 Protein, Human, Recombinant (His & Avi) LY9,T100,AI893573,SLAMF3,Lgp100,CD229	Human	HEK293 Cells
	CD229 was strongly and homogeneously overexpressed on the PC of patients with monoclonal gammopathy of undetermined significance (MGUS), smoldering myeloma, MM, and PC leukemia. CD229 was particularly overexpressed on those PC showing an abnormal phenotype such as expression of CD56. Most importantly, CD229 was also highly expressed on those cells in the patients' BM displaying the phenotype of chemotherapy-resistant and myeloma-propagating cells. CD229 Protein, Human, Recombinant (His & Avi) is...
TMPK-01270	CD117 Protein, Cynomolgus/Rhesus macaque, Recombinant (His) KIT,PBT,c-kit,CD117,SCFR,ckit	Cynomolgus,Rhesus	HEK293 Cells
	The c-kit proto-oncogen (CD117) has been shown to be present in several cell types including normal and neoplastic hemopoietic cells. Among normal BM cells, CD117 expression has been found in about half of the CD34 precursors including progenitors committed to the erythroid, granulo-monocytic, and megakaryocytic cell lineages.
TMPH-02696	GNAQ Protein, Mouse, Recombinant (His & Myc) Guanine nucleotide-binding protein G(q) subunit alpha,Gnaq,G...	Mouse	E. coli
	Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Regulates B-cell selection and survival and is required to prevent B-cell-dependent autoimmunity. Regulates chemotaxis of BM-derived neutrophils and dendritic cells (in vitro). Transduces FFAR4 signaling in response to long-chain fatty acids (LCFAs).
TMPK-00777	CD117 Protein, Mouse, Recombinant (His) ckit,PBT,SCFR,KIT,CD117,c-kit	Mouse	HEK293 Cells
	The c-kit proto-oncogen (CD 117) has been shown to be present in several cell types including normal and neoplastic hemopoietic cells. Among normal BM cells, CD117 expression has been found in about half of the CD34 precursors including progenitors committed to the erythroid, granulo-monocytic, and megakaryocytic cell lineages. CD117 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 56.63 kDa and the accession number is P05...
TMPK-00805	CD117 Protein, Human, Recombinant (His & Avi), Biotinylated CD117,EC 2.7.10,EC 2.7.10.1,c-kit,KIT,SCFR,PBT,ckit	Human	HEK293 Cells
	The c-kit proto-oncogen (CD 117) has been shown to be present in several cell types including normal and neoplastic hemopoietic cells. Among normal BM cells, CD117 expression has been found in about half of the CD34 precursors including progenitors committed to the erythroid, granulo-monocytic, and megakaryocytic cell lineages. CD117 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 58.60 kDa and the...
TMPK-00358	CD229 Protein, Human, Recombinant (His & Avi), Biotinylated T100,Lgp100,LY9,AI893573,CD229,SLAMF3	Human	HEK293 Cells
	CD229 was strongly and homogeneously overexpressed on the PC of patients with monoclonal gammopathy of undetermined significance (MGUS), smoldering myeloma, MM, and PC leukemia. CD229 was particularly overexpressed on those PC showing an abnormal phenotype such as expression of CD56. Most importantly, CD229 was also highly expressed on those cells in the patients' BM displaying the phenotype of chemotherapy-resistant and myeloma-propagating cells. CD229 Protein, Human, Recombinant (His & Avi), B...

重组蛋白

ALCAM Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00340

Species: Human

Expression System: HEK293 Cells

ALCAM Protein, Mouse, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00339

Species: Mouse

Expression System: HEK293 Cells

ALCAM Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated

Cat.No: TMPK-00341

Species: Human

Expression System: HEK293 Cells

SARS-CoV-2 BM.1.1.1 (Omicron) Spike RBD Protein (His)

Cat.No: TMPY-06618

Species: SARS-CoV-2

Expression System: HEK293 Cells

SARS-CoV-2 BM.1.1.1 (Omicron) Spike S1+S2 trimer Protein (His)

Cat.No: TMPY-06633

Species: SARS-CoV-2

Expression System: HEK293 Cells

CD229 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00357

Species: Human

Expression System: HEK293 Cells

CD117 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)

Cat.No: TMPK-01270

Species: Cynomolgus,Rhesus

Expression System: HEK293 Cells

GNAQ Protein, Mouse, Recombinant (His & Myc)

Cat.No: TMPH-02696

Species: Mouse

Expression System: E. coli

CD117 Protein, Mouse, Recombinant (His)

Cat.No: TMPK-00777

Species: Mouse

Expression System: HEK293 Cells

CD117 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00805

Species: Human

Expression System: HEK293 Cells

CD229 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00358

Species: Human

Expression System: HEK293 Cells

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