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Search Results for " becn1 "

Targets Recommended: Antiviral SARS-CoV

1

抑制剂 & 化合物

6

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T77516	SARS-CoV-2-IN-39	Antiviral; SARS-CoV	Immunology/Inflammation; Microbiology/Virology
	SARS-CoV-2-IN-39是一种 SARS-CoV-2 抑制剂，EC50 为 1 μM。 SARS-CoV-2-IN-39 具有抗病毒活性，通过抑制 SKP2 蛋白并稳定 BECN1 来抑制 SARS-CoV-2。

化合物

SARS-CoV-2-IN-39

Cat.No: T77516

Target: Antiviral, SARS-CoV

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-01004	Beclin-1 Protein, Human, Recombinant (His) Protein GT197,GT197,Coiled-coil myosin-lik...	Human	E. coli
	Beclin-1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 57.9 kDa and the accession number is Q14457.
TMPH-02538	Beclin-1 Protein, Mouse, Recombinant (His & SUMO) Beclin-1,GT197,Coiled-coil myosin-like BCL...	Mouse	E. coli
	Plays a central role in autophagy. Acts as core subunit of different PI3K complex forms that mediate formation of phosphatidylinositol 3-phosphate and are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2. Essential f...
TMPH-03296	Galectin-3/LGALS3 Protein, Rat, Recombinant (His) Lgals3,IgE-binding protein,Carbohydrate-binding protein 35,L...	Rat	E. coli
	Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells. Together with TRIM16, coordinates the recognition of membrane damage with mobilization of the core autop...
TMPY-00473	NRBF2 Protein, Human, Recombinant (His & GST) NRBF-2,nuclear receptor binding factor 2,COPR2,COPR1	Human	Baculovirus Insect Cells
	NRBF2 (Nuclear Receptor Binding Factor 2) is a Protein Coding gene. The encoded protein may modulate transcriptional activation by target nuclear receptors. It is widely expressed in the appendix, placenta, and other tissues. NRBF2/Atg38 has been identified as the fifth subunit of the macroautophagy/autophagy class III phosphatidylinositol 3-kinase (PtdIns3K) complex, along with ATG14/Barkor, BECN1/Vps30, PIK3R4/p150/Vps15, and PIK3C3/Vps34. NRBF2 is a critical molecular switch of PtdIns3K and a...
TMPH-02632	TRIM21 Protein, Mouse, Recombinant (E. coli, His) Trim21,52 kDa ribonucleoprotein autoantigen Ro/SS-A...	Mouse	E. coli
	E3 ubiquitin-protein ligase whose activity is dependent on E2 enzymes, UBE2D1, UBE2D2, UBE2E1 and UBE2E2. Forms a ubiquitin ligase complex in cooperation with the E2 UBE2D2 that is used not only for the ubiquitination of USP4 and IKBKB but also for its self-ubiquitination. Component of cullin-RING-based SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes such as SCF(SKP2)-like complexes. A TRIM21-containing SCF(SKP2)-like complex is shown to mediate ubiquitination of CDKN1B ('Thr...
TMPH-02633	TRIM21 Protein, Mouse, Recombinant (His) Tripartite motif-containing protein 21,E3 ubiquitin...	Mouse	Baculovirus Insect Cells
	E3 ubiquitin-protein ligase whose activity is dependent on E2 enzymes, UBE2D1, UBE2D2, UBE2E1 and UBE2E2. Forms a ubiquitin ligase complex in cooperation with the E2 UBE2D2 that is used not only for the ubiquitination of USP4 and IKBKB but also for its self-ubiquitination. Component of cullin-RING-based SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes such as SCF(SKP2)-like complexes. A TRIM21-containing SCF(SKP2)-like complex is shown to mediate ubiquitination of CDKN1B ('Thr...

重组蛋白

Beclin-1 Protein, Human, Recombinant (His)

Cat.No: TMPH-01004

Species: Human

Expression System: E. coli

Beclin-1 Protein, Mouse, Recombinant (His & SUMO)

Cat.No: TMPH-02538

Species: Mouse

Expression System: E. coli

Galectin-3/LGALS3 Protein, Rat, Recombinant (His)

Cat.No: TMPH-03296

Species: Rat

Expression System: E. coli

NRBF2 Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-00473

Species: Human

Expression System: Baculovirus Insect Cells

TRIM21 Protein, Mouse, Recombinant (E. coli, His)

Cat.No: TMPH-02632

Species: Mouse

Expression System: E. coli

TRIM21 Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02633

Species: Mouse

Expression System: Baculovirus Insect Cells

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