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Search Results for " bcl6 in 6 "

Targets Recommended: BCL

9

抑制剂 & 化合物

15

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T60008	BCL6-IN-6	BCL	Apoptosis
	BCL6-IN-6 是 Bcl-6 的抑制剂，可用于关于弥漫性大 B 细胞淋巴瘤的研究。 BCL6-IN-6 阻断 Bcl-6 与其辅阻遏物的相互作用，并以剂量依赖性方式重新激活 Bcl-6 靶基因。
T10487	BCL6-IN-3	BCL; Others; DNA	Apoptosis; DNA Damage/DNA Repair; Others
	BCL6-IN-3是一种有效的BCL6抑制剂，对SU-DHL4细胞中的GI50为70 nM。BCL6- in -3调控细胞活化、分化、DNA 损伤和凋亡过程，具有抗肿瘤活性。
T39788	BCL6-IN-5 BCL6-IN-5	Others	Others
	BCL6-IN-5 is a highly effective inhibitor of BCL6. It exhibits a pIC50 value of 5.82.
T14515	BCL6-IN-8c	Others	Others
	BCL6-IN-8c is an orally active and potent inhibitor of B-cell lymphoma 6 (BCL6)-corepressor interaction(IC50 of 0.10 μM in cell-free enzyme-linked immunosorbent assay).
T36484	BCL6-IN-4 BCL6-IN-4	Others	Others
	BCL6-IN-4, a potent inhibitor of B-cell lymphoma 6 (BCL6), exhibits anti-tumor activities with an inhibitory concentration 50 (IC50) value of 97 nM[1].
T73869	BCL6 PROTAC 1	Others	Others
	BCL6PROTAC1 是一种选择性的 B 细胞淋巴瘤 6 (BCL6)PROTAC。BCL6PROTAC1 抑制 BCL6 细胞报告，IC50值为 8.8 µM。BCL6PROTAC1 在弥漫性大 B 细胞淋巴瘤 (DLBCL) 细胞系中显著降解 BCL6。BCL6PROTAC1 可用于肿瘤相关研究。
T3940	CID5721353 BCL6 inhibitor	Apoptosis; BCL	Apoptosis
	CID5721353 (BCL6 inhibitor) 是一种 B 细胞淋巴瘤 6 抑制剂，IC50为 212 μM，Ki 值为 147 μM。它可在体内外破坏 BCL6/辅助阻遏物复合物，并显示与 BTB 沟内的关键位点结合。
T75105	OICR12694 TFA	Others	Others
	OICR12694 (JNJ-65234637) TFA 是一种口服有效的 B 细胞淋巴瘤 6 (BCL6) 抑制剂。
T62854	BCL6-IN-9	Others	Others
	BCL6-IN-9 (compound 1) 是一种 B 细胞淋巴瘤 6 蛋白 (BCL6) 的有效抑制剂 (IC50: 3.9 nM)，能够用于研究癌。

化合物

Cat.No: T60008

Target: BCL

Cat.No: T10487

Target: BCL, Others, DNA

Cat.No: T39788

Synonym: BCL6-IN-5

Target: Others

Cat.No: T14515

Target: Others

Cat.No: T36484

Synonym: BCL6-IN-4

Target: Others

BCL6 PROTAC 1

Cat.No: T73869

Target: Others

Cat.No: T3940

Synonym: BCL6 inhibitor

Target: Apoptosis, BCL

Cat.No: T75105

Target: Others

Cat.No: T62854

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-01000	BCL6 Protein, Human, Recombinant ZNF51,LAZ3,ZBTB27,Zinc finger protein<...	Human	E. coli
	BCL6 Protein, Human, Recombinant is expressed in E. coli.
TMPH-00999	BCL6 Protein, Human, Recombinant (His) BCL-5,B-cell lymphoma 5 protein,BCL	Human	E. coli
	BCL6 Protein, Human, Recombinant (His) is expressed in E. coli.
TMPY-02430	BCL6 Protein, Human, Recombinant (aa 1-150, His & Trx) BCL5,ZNF51,B-cell CLL/lymphoma 6,...	Human	E. coli
	The protein encoded by this gene is an evolutionarily conserved 95-kDa protein containing six C-terminal zinc-finger motifs and an N-terminal POZ domain. It has been reported that BCL-6 is present in DNA-binding complexes in nuclear extracts from various B-cell lines. There are many relationships between non-Hodgkin's lymphoma, diffuse large cell lymphoma and BCL6’s translocations. BCL6 can repress transcription from promoters linked to its DNA target sequence and this activity is dependent upon...
TMPJ-00567	NCR1 Protein, Human, Recombinant (hFc) hNKp46,Natural cytotoxicity triggerin<...	Human	HEK293 Cells
	Natural cytotoxicity triggering receptor 1(NCR1) is a single-pass type I membrane protein .It contains 2 Ig-like (immunoglobulin-like) domains and belongs to the natural cytotoxicity receptor (NCR) family. The protein is a natural killer (NK) lymphocyte-activating receptor. It is involved in major aspects of NK immune function and shows a high degree of lineage specificity in blood and bone marrow.
TMPY-03128	LAIR1 Protein, Mouse, Recombinant (hFc) leukocyte-associated immunoglobulin-like receptor 1...	Mouse	HEK293 Cells
	LAIR1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 39.6 kDa and the accession number is Q8BG84-6.
TMPJ-00827	Tau-D Protein, Human, Recombinant (His) PHF-Tau,MAPTL,MAPT,Paired Helical Filament-Tau,Microtubule-A...	Human	E. coli
	Microtubule-Associated Protein TAU is abundantly expressed in neurons of the central nervous system and less commonly expressed elsewhere, but is also expressed at very low levels in CNS astrocytes and oligodendrocytes. Tau interacts with tubulin to stabilize microtubules and promotes tubulin assembly into microtubules. The C-terminus of TAU binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau acts as a linker protein. When tau is defective,...
TMPY-05798	VEGF145 Protein, Human, Recombinant 血管内皮生长因子,vascular endothelial growth factor A,VPF,MVCD1,VEGF...	Human	HEK293 Cells
	VEGF145 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 16.92 kDa and the accession number is P15692-6.
TMPY-04277	CD45 Protein, Mouse, Recombinant (hFc) Cd45,protein tyrosine phosphatase, recepto...	Mouse	HEK293 Cells
	CD45 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 71.7 kDa and the accession number is P06800-6.
TMPY-02600	NRG1 beta 1 Protein, Human, Recombinant (EGF Domain, hFc) neuregulin 1,HRGA,NRG1 β1,HGL,MST131,MSTP131,HRG,AR...	Human	HEK293 Cells
	NRG1 beta 1 Protein, Human, Recombinant (EGF Domain, hFc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 36.7 kDa and the accession number is Q02297-6.
TMPY-02705	NRG1 beta 1 Protein, Human, Recombinant (hFc) MSTP131,HRG1,NRG1-IT2,ARIA,HGL,SMDF,GGF,HRG,NDF,MST131,neure...	Human	HEK293 Cells
	NRG1 beta 1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 55.2 kDa and the accession number is Q02297-6.
TMPY-03010	NRG1 beta 1 Protein, Human, Recombinant NDF,GGF,MSTP131,Neuregulin 1,MST131,ARIA,NRG1-IT2,S...	Human	HEK293 Cells
	NRG1 beta 1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 26.8 kDa and the accession number is Q02297-6.
TMPK-00614	NKp46/NCR1 Protein, Human, Recombinant (His) NKp46,MAR-1,Ly94,NCR1,NKP46	Human	HEK293 Cells
	NKp46, along with NKp30 and NKp44, are activating receptors that have been collectively termed the natural cytotoxicity receptors (NCR).These receptors lack significant sequence homology to one another. They are expressed almost exclusively by NK cells and play a major role in triggering some of the key lytic activities of NK cells. NKp46/NCR1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 27.5 kDa and the accession numb...
TMPK-00615	NKp46/NCR1 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated CD335,NCR1,NKp46,NKP46FL...	Human	HEK293 Cells
	NKp46, along with NKp30 and NKp44, are activating receptors that have been collectively termed the natural cytotoxicity receptors (NCR).These receptors lack significant sequence homology to one another. They are expressed almost exclusively by NK cells and play a major role in triggering some of the key lytic activities of NK cells. NKp46/NCR1 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular we...
TMPK-01364	SIRP alpha V6 Protein, Human, Recombinant (His & Avi), Biotinylated SIRP α,MFR,SHPS1,SIRPA,BIT,SHPS-1,MYD-1,SIRP alpha,P84,CD172...	Human	HEK293 Cells
	Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction. SIRP alpha V6 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian c...
TMPK-01358	SIRP alpha V6 Protein, Human, Recombinant (His & Avi) P84,SIRPA,SIRP alpha,SHPS-1,MFR,BIT,MYD1,SIRP α V6	Human	HEK293 Cells
	Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction. SIRP alpha V6 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-Hi...

重组蛋白

BCL6 Protein, Human, Recombinant

Cat.No: TMPH-01000

Species: Human

Expression System: E. coli

BCL6 Protein, Human, Recombinant (His)

Cat.No: TMPH-00999

Species: Human

Expression System: E. coli

BCL6 Protein, Human, Recombinant (aa 1-150, His & Trx)

Cat.No: TMPY-02430

Species: Human

Expression System: E. coli

NCR1 Protein, Human, Recombinant (hFc)

Cat.No: TMPJ-00567

Species: Human

Expression System: HEK293 Cells

LAIR1 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-03128

Species: Mouse

Expression System: HEK293 Cells

Tau-D Protein, Human, Recombinant (His)

Cat.No: TMPJ-00827

Species: Human

Expression System: E. coli

VEGF145 Protein, Human, Recombinant

Cat.No: TMPY-05798

Species: Human

Expression System: HEK293 Cells

CD45 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-04277

Species: Mouse

Expression System: HEK293 Cells

NRG1 beta 1 Protein, Human, Recombinant (EGF Domain, hFc)

Cat.No: TMPY-02600

Species: Human

Expression System: HEK293 Cells

NRG1 beta 1 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-02705

Species: Human

Expression System: HEK293 Cells

NRG1 beta 1 Protein, Human, Recombinant

Cat.No: TMPY-03010

Species: Human

Expression System: HEK293 Cells

NKp46/NCR1 Protein, Human, Recombinant (His)

Cat.No: TMPK-00614

Species: Human

Expression System: HEK293 Cells

NKp46/NCR1 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated

Cat.No: TMPK-00615

Species: Human

Expression System: HEK293 Cells

SIRP alpha V6 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-01364

Species: Human

Expression System: HEK293 Cells

SIRP alpha V6 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-01358

Species: Human

Expression System: HEK293 Cells

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