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Search Results for " bbp "

Targets Recommended: Phosphatase

10

抑制剂 & 化合物

4

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T9196	IACS-13909 BBP-398	Phosphatase	Metabolism
	IACS-13909 (BBP-398) 是具有口服活性的、选择性的 SHP2变构抑制剂，其 IC50=15.7 nM，Kd=32 nM。与其他磷酸酶相比，它对 SHP2的选择性更高。它能够抑制受体酪氨酸激酶 (RTK)/MAPK 途径的信号传导，并具有抗癌作用。
T0640	Benzyl butyl phthalate BBP,邻苯二甲酸丁苄酯,1,2-benzenedicarboxylic acid,butyl phenylmethyl ester,Butyl benzyl phthalate	Others; Aryl Hydrocarbon Receptor	Immunology/Inflammation; Others
	Benzyl butyl phthalate (1,2-benzenedicarboxylic acid) 是邻苯二甲酸酯的一员，可激活乳腺癌细胞中的芳香烃受体，刺激 SPHK1/S1P/S1PR3 信号传导，促进转移性乳腺癌干细胞的形成。它通过上调 Zeb1 的表达，可引起血管瘤细胞的迁移和侵袭。
T131719	Compound TBBP06469	Others	Others
	Compound TBBP06469 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T131719，CAS号为 3682-03-9。
T131722	Compound TBBP04531	Others	Others
	Compound TBBP04531 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T131722，CAS号为 4192-77-2。
T73923	Ep300/CREBBP-IN-4	Others	Others
	Ep300/CREBBP-IN-4 (Example 56) 是一种有效的Ep300和CREBBP 抑制剂，IC50分别为 0.024 μM 和 0.064 μM。Ep300/CREBBP-IN-4 可用于癌症研究。
T131728	Compound TBBP06234	Others	Others
	Compound TBBP06234 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T131728，CAS号为 39886-76-5。
T27082	CREBBP-IN-9 CREBBPIN9,CREBBP IN 9	Others	Others
	CREBBP-IN-9, a CREBBP inhibitor, acts on the bromodomain of the protein.
T73920	Ep300/CREBBP-IN-8	Others	Others
	Ep300/CREBBP-IN-8 (Example 37) 是一种有效的和具有口服活性的 Ep300和CREBBP 抑制剂，IC50分别为 0.014 μM 和 0.018 μM。Ep300/CREBBP-IN-8 可用于癌症研究。
T73921	Ep300/CREBBP-IN-2	Others	Others
	Ep300/CREBBP-IN-2 (Example 73) 是一种有效的和具有口服活性的Ep300和CREBBP 抑制剂，IC50分别为 0.052 μM 和 0.148 μM。Ep300/CREBBP-IN-2 可用于癌症研究。
T73922	Ep300/CREBBP-IN-3	Others	Others
	Ep300/CREBBP-IN-3 (Example 61) 是一种有效的Ep300和CREBBP 抑制剂，IC50分别为 0.056 μM 和 0.095 μM。Ep300/CREBBP-IN-3 可用于癌症研究。

化合物

Cat.No: T9196

Synonym: BBP-398

Target: Phosphatase

Benzyl butyl phthalate

Cat.No: T0640

Synonym: BBP,邻苯二甲酸丁苄酯,1,2-benzenedicarboxylic acid,butyl phenylmethyl ester,Butyl benzyl phthalate

Target: Others, Aryl Hydrocarbon Receptor

Compound TBBP06469

Cat.No: T131719

Target: Others

Compound TBBP04531

Cat.No: T131722

Target: Others

Ep300/CREBBP-IN-4

Cat.No: T73923

Target: Others

Compound TBBP06234

Cat.No: T131728

Target: Others

Cat.No: T27082

Synonym: CREBBPIN9,CREBBP IN 9

Target: Others

Ep300/CREBBP-IN-8

Cat.No: T73920

Target: Others

Ep300/CREBBP-IN-2

Cat.No: T73921

Target: Others

Ep300/CREBBP-IN-3

Cat.No: T73922

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-00059	TM2D1 Protein, Human, Recombinant (mFc) TM2 domain containing 1,BBP	Human	HEK293 Cells
	TM2D1 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 35.1 kDa and the accession number is Q9BX74.
TMPH-02866	RBBP9 Protein, Mouse, Recombinant (His) Retinoblastoma-binding protein 9,Putative hydrolase RBBP...	Mouse	P. pastoris (Yeast)
	Serine hydrolase whose substrates have not been identified yet. May negatively regulate basal or autocrine TGF-beta signaling by suppressing SMAD2-SMAD3 phosphorylation. May play a role in the transformation process due to its capacity to confer resistance to the growth-inhibitory effects of TGF-beta through interaction with RB1 and the subsequent displacement of E2F1. RBBP9 Protein, Mouse, Recombinant (His) is expressed in yeast with C-6xHis tag. The predicted molecular weight is 22.4 kDa and t...
TMPH-01483	RBBP7 Protein, Human, Recombinant (His & SUMO) Histone acetyltransferase type B subunit 2,Histone-binding p...	Human	E. coli
	RBBP7 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 63.8 kDa and the accession number is Q16576.
TMPH-01158	CREBBP Protein, Human, Recombinant (GST) CREBBP,CREB-binding protein,CBP	Human	E. coli
	CREBBP Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 40.7 kDa and the accession number is Q92793.

重组蛋白

TM2D1 Protein, Human, Recombinant (mFc)

Cat.No: TMPY-00059

Species: Human

Expression System: HEK293 Cells

RBBP9 Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02866

Species: Mouse

Expression System: P. pastoris (Yeast)

RBBP7 Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-01483

Species: Human

Expression System: E. coli

CREBBP Protein, Human, Recombinant (GST)

Cat.No: TMPH-01158

Species: Human

Expression System: E. coli

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