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Targets Recommended: HBV

340

抑制剂 & 化合物

102

天然产物

6

化合物库

1

TargetMol 试剂盒

324

重组蛋白

4

同位素标记化合物

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Cat. No. Product Name
L8700 铁死亡化合物库

779 compounds
779 种与铁死亡通路相关的化合物,可用于高通量和高内涵筛选;
L4010 已知活性化合物库

22555 compounds
22555 个已知活性化合物的集合,可用于高通量筛选、高内涵筛选、细胞诱导和靶点确认;
L1300 PI3K/Akt/mTOR 化合物库

420 compounds
420 种与PI3K/Akt/mTOR 相关的生物活性小分子化合物的特有集合,用于PI3K/Akt/mTOR 相关研究以及高通量、高内涵筛选;
L6120 黄酮类天然产物库

514 compounds
514 种黄酮类天然产物的独特集合,可用于高通量筛选和高内涵筛选;
L8710 铜死亡化合物库

400 compounds
TargetMol 铜死亡化合物库集合了 400 种与铜死亡相关的化合物,可以用于铜死亡机制及相关疾病研究
L2550 谷氨酰胺代谢化合物库

565 compounds
565 种谷氨酰胺代谢相关的分子,可以用于高通量和高内涵筛选;

化合物库

铁死亡化合物库
Cat.No: L8700
Compounds: 779
已知活性化合物库
Cat.No: L4010
Compounds: 22555
PI3K/Akt/mTOR 化合物库
Cat.No: L1300
Compounds: 420
黄酮类天然产物库
Cat.No: L6120
Compounds: 514
铜死亡化合物库
Cat.No: L8710
Compounds: 400
谷氨酰胺代谢化合物库
Cat.No: L2550
Compounds: 565
Cat. No. Product Name Form Specificity Of Inhibition
C0052 Penicillin-Streptomycin-Amphotericin B Solution (100×), Sterile

青霉素-链霉素-两性霉素B三抗溶液(100×),灭菌

Solution in <em>b</em>ottle

TargetMol 试剂盒

青霉素-链霉素-两性霉素B三抗溶液(100×),灭菌
Cat.No: C0052
Cat. No. Product Name Target Signaling Pathways
T11669 IR415

HBV Microbiology/Virology
IR415 选择性地与 HBx 相互作用 (Kd=2 nM) 并阻断 HBV 介导的 RNAi 抑制,逆转 HBx 蛋白对 Dicer 核糖核酸内切酶活性的抑制作用。IR415 具有抗 HBV 的活性。
T9541 CTB

Cholera Toxin B subunit

Epigenetic Reader Domain Chromatin/Epigenetic
CTB (Cholera Toxin B subunit) 是一种 p300 组蛋白乙酰转移酶的激活剂,可诱导 MCF-7 细胞凋亡。
T9919 Alemtuzumab

Others Others
Alemtuzumab 是人源化抗 CD52单克隆抗体, CD52是一种表达于大多数淋巴细胞以及少数的髓细胞类型的糖蛋白。Alemtuzumab 与能够特异性作用于 CD52 抗原,诱导淋巴细胞深度耗竭,恢复具有调节表型的 T 细胞和 B 细胞。
T39437 Cevidoplenib dimesylate

Syk Angiogenesis; Tyrosine Kinase/Adaptors
Cevidoplenib dimesylate 是一种脾酪氨酸激酶 (Syk) 抑制剂,具有抗炎和免疫调节特性。
T1902 BAY 11-7082

BAY 11-7821

Apoptosis; Others; B/IKK; DUB; Autophagy Apoptosis; Autophagy; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; NF-κB; Others; Ubiquitination
BAY 11-7082 (BAY 11-7821) 是一种 NF-κB 抑制剂,可抑制 TNFα 诱导的 IκBα 磷酸化 (IC50=10 μM)。BAY 11-7082 也是一种泛素特异性蛋白酶 USP7 和 USP21 的抑制剂 (IC50=0.19/0.96 μM)。
T1120 Dacarbazine

Imidazole Carboxamide,达卡巴嗪,DTIC-Dome

Apoptosis; Nucleoside Antimetabolite/Analog; DNA/RNA Synthesis Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair
Dacarbazine (DTIC-Dome) 是一种抗肿瘤剂,对黑色素瘤具有显着的活性。
T10096L Voruciclib

CDK Cell Cycle/Checkpoint
Voruciclib 是一种具有口服活性和选择性 CDK 抑制剂,Ki 为 0.626 nM-9.1 nM。它在多种弥漫性大 B 细胞淋巴瘤模型中抑制 MCL-1 的表达。它有效阻断 MCL-1 的转录调节子 CDK9。
T2302 CNX-774

CNX 774

BTK Angiogenesis; Tyrosine Kinase/Adaptors
CNX-774 是一种选择性的、具有口服活性的、不可逆的 BTK 抑制剂 (IC50<1 nM)。它能够特异性靶向 Btk 的 Cys 481进行共价修饰。
T4335 GNE-617

GNE617

NAMPT Metabolism
GNE-617 是一种新型的、特异性的Nampt 抑制剂,在A549细胞中IC50为18.9nM。
T12367 Parsaclisib

INCB050465

PI3K PI3K/Akt/mTOR signaling
Parsaclisib (INCB050465) 是有效的、选择性的、具有口服活性的PI3Kδ抑制剂,其 IC50=1 nM。它相对于其他 PI3K I 类同工型的选择性约为 20000 倍。它可用于复发或难治性 B 细胞恶性肿瘤的研究。
T12171 Nampt-IN-5

P450; NAMPT Metabolism
Nampt-IN-5 是烟酰胺磷酸核糖基转移酶抑制剂。它可抑制 A2780 和 COR-L23 细胞,IC50值分别为 0.7 nM 和 3.9 nM。它还抑制 CYP3A4 活性。
T8308 NL-1

Mitochondrial Metabolism; Autophagy Autophagy; Metabolism
NL-1 是一种mitoNEET 抑制剂,具有抗白血病作用。它抑制 REH 和 REH/Ara-C 细胞生长,IC50分别为 47.35 µM 和 56.26 µM。
T26324 VU0071063

VU 0071063,VU-0071063

Potassium Channel Membrane transporter/Ion channel
VU0071063 是特异的Kir6.2/SUR1开启剂 (EC50=7.44 μM),可用于研究Kir6.2 /SUR1在大脑和胰腺中的表达。它可以诱导 β 细胞膜电位的超极化从而抑制胰岛素的分泌。
T6682 STF-118804

STF 118804,STF118804

Apoptosis; NAMPT Apoptosis; Metabolism
STF-118804是一种烟酰胺磷酸核糖基转移酶 Nampt 高选择性抑制剂,降低大多数 B-ALL 细胞系的活力,IC50 <10 nM。
T16040 Mepazine

甲哌啶嗪,Pecazine

Apoptosis; MALT Apoptosis; Immunology/Inflammation
Mepazine (Pecazine) 是一种有效的特异性 MALT1 抑制剂。 Mepazine 抑制 GSTMALT1 全长和 GSTMALT1 325-760,IC50 为 0.83 μM 和 0.42 μM。 Mepazine 增强细胞凋亡并影响细胞活力。
T9203 JH-X-119-01

IRAK Immunology/Inflammation; NF-κB
JH-X-119-01 是白介素 1 受体相关激酶 1 的选择性抑制剂。它能够改善 LPS 诱导的小鼠败血症。它可以抑制 IRAK1(IC50:9 nM),在浓度达到 10 μM 时,也不会对 IRAK4 产生抑制作用。
T4337 PCI 29732

PCI29732,PCI-29732

Others; BCRP; BTK Angiogenesis; Membrane transporter/Ion channel; Others; Tyrosine Kinase/Adaptors
PCI 29732 是一种有效的可逆BTK 抑制剂,对 BTK、Lck 和 Lyn 的Kiapp 值分别为 8.2、4.6 和 2.5 nM。它通过竞争性结合ABCG2 的 ATP 结合位点来抑制ABCG2的功能。
T22450 Tyrphostin B44, (+) enantiomer

酪氨酸磷酸化抑制剂AG 835

EGFR Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
Tyrphostin B44, (+) enantiomer 是一种表皮生长因子受体 (EGFR) 激酶抑制剂,IC50 为 0.86 μM,活性低于 (-) 对映体。
T9696 β-catenin-IN-2

Wnt/beta-catenin Cytoskeletal Signaling; Stem Cells
β-catenin-IN-2 是有效的β-catenin 抑制剂。β-catenin-IN-2在结直肠癌中有研究的价值。
T4376 Nampt-IN-1

LSN3154567

c-Fms; NAMPT; CSF-1R Metabolism; Tyrosine Kinase/Adaptors
Nampt-IN-1 (LSN3154567) 是选择性的 NAMPT 抑制剂,能够抑制纯化的 NAMPT,IC50=3.1 nM。
T3189 B7/CD28 interaction inhibitor 1

CTLA-4 inhibitor

Others Others
B7/CD28 interaction inhibitor 1 (CTLA-4 inhibitor) 是B7.1-CD28相互作用抑制剂(IC50:50 nM)。
T12186 Navitoclax-piperazine

ABT-263-piperazine

BCL; Ligands for Target Protein for PROTAC Apoptosis; PROTAC
Navitoclax-piperazine (ABT-263-piperazine) 是一种特大型 B 细胞淋巴瘤(BCL-XL)抑制剂。它和 E3 泛素连接酶的 VHL 配体可用来合成 PROTAC DT2216。
T1998 CHS-828

CHS 828,GMX1778

Apoptosis; NAMPT Apoptosis; Metabolism
CHS-828 (GMX1778) 是一种竞争性的烟酰胺磷酸化转移酶抑制剂,IC50值 <25 nM。它通过降低细胞中的 NAD+水平发挥细胞毒性作用,具有抗癌活性。
T9195 SHR0302

ARQ252

Apoptosis; JAK Angiogenesis; Apoptosis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells
SHR0302 (ARQ252) 是一种具有口服活性的 JAK 抑制剂。它对 JAK1的结合力是 JAK2的 10 倍以上,是 JAK3的 77 倍,是 Tyk2的 420 倍。它抑制JAK1-STAT3磷酸化并诱导肝星状细胞凋亡,具有抗增殖和抗炎作用。
T9831 MKC-1

Ro-31-7453

Apoptosis; Akt; Microtubule Associated; mTOR Apoptosis; Cytoskeletal Signaling; PI3K/Akt/mTOR signaling
MKC-1 (Ro-31-7453) 是一种口服生物可利用的小分子双吲哚基马来酰亚胺细胞周期抑制剂,具有潜在的抗肿瘤活性。
T14367 AZ1495

IRAK; CDK; Haspin Kinase Cell Cycle/Checkpoint; Immunology/Inflammation; NF-κB
AZ1495 是一种口服有活性的白介素-1受体相关激酶 4(IRAK4)抑制剂,能够作用于 IRAK4 (IC50:5 nM)和 IRAK1 (IC50:23 nM)。可用于研究突变型 MYD88L265P 弥漫性 B 细胞淋巴瘤 (DLBCL) 。
T5354 IRAK4-IN-7

CA-4948

IRAK Immunology/Inflammation; NF-κB
IRAK4-IN-7 (CA-4948) 是白介素 1 受体相关激酶 4 (IRAK4) 的选择性抑制剂,口服有活性。它可用于研究癌症以及炎症疾病。
T12854 SBI-797812

NAMPT Metabolism
SBI-797812 是在结构上类似于活性位点定向的 NAMPT 抑制剂的化合物,能够阻断这些抑制剂与 NAMPT 的结合。 它将 NAMPT 反应平衡转向 NMN 形成,提高 NAMPT 对 ATP 的亲和力,稳定 His247 处的磷酸化 NAMPT,增加焦磷酸盐副产物的消耗,并通过 NAD+钝化反馈抑制。
T3549 Avadomide

CC 122

Apoptosis; E1/E2/E3 Enzyme; Ligand for E3 Ligase Apoptosis; PROTAC; Ubiquitination
Avadomide (CC 122) 是口服有效的cereblon 调节剂,可以调节 cereblon E3 连接酶活性,诱导弥漫性大 B 细胞淋巴瘤细胞凋亡,具有抗肿瘤和免疫调节活性。
T6303L CCT128930 hydrochloride

CCT128930 hydrochloride(885499-61-6 Free base)

Apoptosis; Akt; PKA; mTOR; Autophagy Apoptosis; Autophagy; Cytoskeletal Signaling; PI3K/Akt/mTOR signaling; Tyrosine Kinase/Adaptors
CCT128930 hydrochloride (CCT128930 hydrochloride) 是一种选择性 AKT 抑制剂,具有抗肿瘤活性。它通过靶向 AKT 的 Met282 (PKA-AKT 嵌合体的 Met173),对 PKA 激酶具有 28 倍的选择性,对 p70S6K 具有 20 倍的选择性。
T8656 CAY10404

3-(4-METHYLSULPHONYLPHENYL)-4-PHENYL-5-T

Apoptosis; Akt; COX Apoptosis; Cytoskeletal Signaling; Immunology/Inflammation; Neuroscience; PI3K/Akt/mTOR signaling
CAY10404 (3-(4-METHYLSULPHONYLPHENYL)-4-PHENYL-5-T) 是一种有效且高度选择性的 COX-2 和 COX-1 抑制剂。 它还是 PKB/Akt 和 MAPK 信号通路的有效抑制剂,可诱导 NSC-LC 细胞凋亡,具有镇痛、抗炎和抗癌活性。
T6104 Cerdulatinib hydrochloride

Cerdulatinib,PRT2070,PRT062070 hydrochloride,PRT062070,PRT2070 hydrochloride

MLK; c-Fms; Tyrosine Kinases; Hippo pathway; JAK; Syk Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; MAPK; Stem Cells; Tyrosine Kinase/Adaptors
Cerdulatinib hydrochloride (PRT2070 hydrochloride) 是一种选择性可逆,具有口服活性、 ATP 竞争性的 SYK 和 JAK 的双重抑制剂,抑制 JAK1、2、3、SYK 和 Tyk2的 IC50值分别为12、6、8、32 和 0.5 nM。它可用于研究自身免疫性疾病和B 细胞恶性肿瘤。
T2644 (E)-Daporinad

Daporinad,(E)-N-[4-(1-BENZOYL-PIPERIDIN-4-YL)-BUTYL]-3-PYRIDIN-3-YL-ACRYLAMIDE,APO866,FK866,达珀利奈

NAMPT; Transferase; Autophagy Autophagy; Metabolism
(E)-Daporinad (FK866) 是一种烟酰胺磷酸核糖基转移酶的小分子抑制剂,具有潜在的抗肿瘤和抗血管生成活性,IC50为 0.09 nM。
T6303 CCT128930

Akt; PKA; S6 Kinase; Autophagy Autophagy; Cytoskeletal Signaling; MAPK; PI3K/Akt/mTOR signaling; Tyrosine Kinase/Adaptors
CCT128930 是一种 ATP 竞争性,选择性 AKT 抑制剂。它通过靶向 AKT 的 Met282 (PKA-AKT 嵌合体的 Met173),对 PKA 激酶具有 28 倍的选择性,对 p70S6K 具有 20 倍的选择性,具有抗肿瘤活性。
T28297 Parsaclisib hydrochloride

Parsaclisib HCl,INCB-50465,INCB 050465,INCB-050465,INCB050465 HCl,INCB 50465,INCB50465 HCl

PI3K PI3K/Akt/mTOR signaling
Parsaclisib hydrochloride (INCB050465 HCl) 是一种选择性的、有效的,具有口服活性的 PI3Kδ抑制剂,IC50=1 nM。它相对于其他 PI3K I 类同工型的选择性约为 20000 倍。它可用于复发或难治性 B 细胞恶性肿瘤的研究。
T77135 Tafasitamab

MOR00208,XmAb5574,Tafasitamab-cxix

Apoptosis; Immunology/Inflammation related Apoptosis; Immunology/Inflammation
Tafasitamab (XmAb5574) 是一种 Fc 修饰的人源化单克隆抗体,靶向人 B 细胞表面抗原 CD19 ,可用于研究弥漫性大B细胞淋巴瘤。
TP1806L BCMA72-80 acetate(2293841-58-2 free base)

Others Others
BCMA72-80 acetate(2293841-58-2 free base) 是一种 HLA-A2 特异性 B 细胞成熟抗原 (BCMA) 肽。它用于研究表达 B 细胞成熟抗原的多发性骨髓瘤和肿瘤。
T36696 DMBA

7,12-Dimethylbenzanthracene,7,12-DMBA,7,12-Dimethylbenz[a]anthracene

Apoptosis Apoptosis
DMBA (7,12-Dimethylbenz[a]anthracene) 可诱导大鼠白血病、肝癌和乳腺癌,诱导 A20.1 小鼠 B 细胞淋巴瘤中的程序性细胞死亡(细胞凋亡)。
T63790 Cbl-b-IN-3

E1/E2/E3 Enzyme Ubiquitination
Cbl-b-IN-3是一种有效的casitas b 系淋巴瘤原癌基因-b (Cbl-b)抑制剂(ic50 < 1 nM)。Cbl-b 是一种环型E3泛素蛋白连接酶,与T 淋巴细胞激活阈值的设定有关。Cbl-b 以不依赖于蛋白水解的方式负调控p85,通过其E3泛素连接酶活性,参与了p85向CD28和T 细胞抗原受体ζ的募集,抑制PI3K 抑制了Cblb-/- t 细胞活化的增强。
T63788 PCLX-001

Others Others
PCLX-001 is a small-molecule compound that acts as an orally active inhibitor of N-myristoyltransferase (NMT), specifically targeting NMT1 and NMT2 with IC50 values of 5 nM and 8 nM, respectively. This compound demonstrates anti-tumor effects and effectively inhibits the early signaling of B-cell receptor (BCR). Consequently, PCLX-001 is a valuable tool for researching B-cell malignancies [1] [2].
TQ0221 Rufloxacin hydrochloride

MF-934 hydrochloride,盐酸芦氟沙星

Antibacterial Microbiology/Virology
Rufloxacin hydrochloride (MF-934 hydrochloride) 是一种氟喹诺酮类抗菌剂,可抑制拓扑异构酶。 Rufloxacin hydrochloride 抑制人单核细胞中的 B 细胞分化。
T3626 Acalabrutinib

ACP-196,阿可替尼

BTK Angiogenesis; Tyrosine Kinase/Adaptors
Acalabrutinib (ACP-196) 是一种不可逆的、高效的、具有口服活性、选择性的第二代BTK 抑制剂。它与 BTK 的 ATP 结合口袋中的 Cys481 共价结合。它在慢性淋巴细胞性白血病 (CLL) 小鼠模型中显示出强大的靶向作用和功效。
T76957 Belimumab

LymphoStat B

TNF Apoptosis
Belimumab(LymphoStat B) 是一种人 IgG1λ 单克隆抗体,对 B 细胞激活因子 (BAFF)有抑制作用。Belimumab 可用于研究疲劳,治疗狼疮性肾炎和系统性红斑狼疮。
T26252 PI3Kδ-IN-3

TC KHNS 11

PI3K PI3K/Akt/mTOR signaling
PI3Kδ-IN-3 (TC KHNS 11) 是一种 PI3Kδ 抑制剂,IC50 值为 9 nM。PI3Kδ-IN-3 具有良好的药代动力学特性且对 B 细胞功能有抑制作用。
T2295 SB-590885

Raf MAPK
SB590885 是一种 B-Raf 抑制剂,Ki 值为 0.16 nM,对其选择性是对 c-Raf 的 11 倍多。
T2059 Purvalanol A

NG-60

Apoptosis; CDK; Autophagy Apoptosis; Autophagy; Cell Cycle/Checkpoint
Purvalanol A (NG-60) 是一种CDK 抑制剂,对 cdc2-cyclin B、cdc2-cyclin B、cdk2-cyclin E、cdk4-cyclin D1 和 cdk5-p35 的IC50值分别为 4、70、35、850 和 75 nM。
T21012 Diflufenican

M&B 38544,吡氟草胺

Others Others
Diflufenican (M&amp;B 38544) 是一种选择性除草剂,用于专门防治某些阔叶杂草。
T14299 AP20187

B/B Homodimerizer

Others Others
AP20187 (B/B Homodimerizer) 是一种细胞渗透性配体,用于二聚化 FK506 结合蛋白 (FKBP) 融合蛋白。它启动生物信号级联和基因表达或破坏蛋白质-蛋白质相互作用。
T76685 Glofitamab

RO7082859,RG 6026,CD20-TCB

Others Others
Glofitamab (RO7082859) 是一种新型针对 CD20 结合 T 细胞的二价抗体。Glofitamab 通过与恶性细胞上的 CD20 结合促使 T 细胞增殖活化和肿瘤细胞杀伤。Glofitamab 可用于缓解复发或难治性 B 细胞淋巴瘤。
T76692 Mosunetuzumab

BTCT-4465A

Others Others
Mosunetuzumab (BTCT-4465A) 是一种基于免疫球蛋白 G1 且靶向 CD20 (B 细胞) 和 CD3 (T 细胞) 的人源化抗体。Mosunetuzumab 重定向 T 细胞以接合和消除恶性 B 细胞,可用于研究复发或难治性 (R/R) B 细胞非霍奇金淋巴瘤 (B-NHL)和难治性滤泡性淋巴瘤。

化合物

IR415
Cat.No: T11669
Synonym:
Target: HBV
CTB
Cat.No: T9541
Synonym: Cholera Toxin B subunit
Target: Epigenetic Reader Domain
Alemtuzumab
Cat.No: T9919
Synonym:
Target: Others
Cevidoplenib dimesylate
Cat.No: T39437
Synonym:
Target: Syk
BAY 11-7082
Cat.No: T1902
Synonym: BAY 11-7821
Target: Apoptosis, Others, IκB/IKK, DUB, Autophagy
Dacarbazine
Cat.No: T1120
Synonym: Imidazole Carboxamide,达卡巴嗪,DTIC-Dome
Target: Apoptosis, Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis
Voruciclib
Cat.No: T10096L
Synonym:
Target: CDK
CNX-774
Cat.No: T2302
Synonym: CNX 774
Target: BTK
GNE-617
Cat.No: T4335
Synonym: GNE617
Target: NAMPT
Parsaclisib
Cat.No: T12367
Synonym: INCB050465
Target: PI3K
Nampt-IN-5
Cat.No: T12171
Synonym:
Target: P450, NAMPT
NL-1
Cat.No: T8308
Synonym:
Target: Mitochondrial Metabolism, Autophagy
VU0071063
Cat.No: T26324
Synonym: VU 0071063,VU-0071063
Target: Potassium Channel
STF-118804
Cat.No: T6682
Synonym: STF 118804,STF118804
Target: Apoptosis, NAMPT
Mepazine
Cat.No: T16040
Synonym: 甲哌啶嗪,Pecazine
Target: Apoptosis, MALT
JH-X-119-01
Cat.No: T9203
Synonym:
Target: IRAK
PCI 29732
Cat.No: T4337
Synonym: PCI29732,PCI-29732
Target: Others, BCRP, BTK
Tyrphostin B44, (+) enantiomer
Cat.No: T22450
Synonym: 酪氨酸磷酸化抑制剂AG 835
Target: EGFR
β-catenin-IN-2
Cat.No: T9696
Synonym:
Target: Wnt/beta-catenin
Nampt-IN-1
Cat.No: T4376
Synonym: LSN3154567
Target: c-Fms, NAMPT, CSF-1R
B7/CD28 interaction inhibitor 1
Cat.No: T3189
Synonym: CTLA-4 inhibitor
Target: Others
Navitoclax-piperazine
Cat.No: T12186
Synonym: ABT-263-piperazine
Target: BCL, Ligands for Target Protein for PROTAC
CHS-828
Cat.No: T1998
Synonym: CHS 828,GMX1778
Target: Apoptosis, NAMPT
SHR0302
Cat.No: T9195
Synonym: ARQ252
Target: Apoptosis, JAK
MKC-1
Cat.No: T9831
Synonym: Ro-31-7453
Target: Apoptosis, Akt, Microtubule Associated, mTOR
AZ1495
Cat.No: T14367
Synonym:
Target: IRAK, CDK, Haspin Kinase
IRAK4-IN-7
Cat.No: T5354
Synonym: CA-4948
Target: IRAK
SBI-797812
Cat.No: T12854
Synonym:
Target: NAMPT
Avadomide
Cat.No: T3549
Synonym: CC 122
Target: Apoptosis, E1/E2/E3 Enzyme, Ligand for E3 Ligase
CCT128930 hydrochloride
Cat.No: T6303L
Synonym: CCT128930 hydrochloride(885499-61-6 Free base)
Target: Apoptosis, Akt, PKA, mTOR, Autophagy
CAY10404
Cat.No: T8656
Synonym: 3-(4-METHYLSULPHONYLPHENYL)-4-PHENYL-5-T
Target: Apoptosis, Akt, COX
Cerdulatinib hydrochloride
Cat.No: T6104
Synonym: Cerdulatinib,PRT2070,PRT062070 hydrochloride,PRT062070,PRT2070 hydrochloride
Target: MLK, c-Fms, Tyrosine Kinases, Hippo pathway, JAK, Syk
(E)-Daporinad
Cat.No: T2644
Synonym: Daporinad,(E)-N-[4-(1-BENZOYL-PIPERIDIN-4-YL)-BUTYL]-3-PYRIDIN-3-YL-ACRYLAMIDE,APO866,FK866,达珀利奈
Target: NAMPT, Transferase, Autophagy
CCT128930
Cat.No: T6303
Synonym:
Target: Akt, PKA, S6 Kinase, Autophagy
Parsaclisib hydrochloride
Cat.No: T28297
Synonym: Parsaclisib HCl,INCB-50465,INCB 050465,INCB-050465,INCB050465 HCl,INCB 50465,INCB50465 HCl
Target: PI3K
Tafasitamab
Cat.No: T77135
Synonym: MOR00208,XmAb5574,Tafasitamab-cxix
Target: Apoptosis, Immunology/Inflammation related
BCMA72-80 acetate(2293841-58-2 free base)
Cat.No: TP1806L
Synonym:
Target: Others
DMBA
Cat.No: T36696
Synonym: 7,12-Dimethylbenzanthracene,7,12-DMBA,7,12-Dimethylbenz[a]anthracene
Target: Apoptosis
Cbl-b-IN-3
Cat.No: T63790
Synonym:
Target: E1/E2/E3 Enzyme
PCLX-001
Cat.No: T63788
Synonym:
Target: Others
Rufloxacin hydrochloride
Cat.No: TQ0221
Synonym: MF-934 hydrochloride,盐酸芦氟沙星
Target: Antibacterial
Acalabrutinib
Cat.No: T3626
Synonym: ACP-196,阿可替尼
Target: BTK
Belimumab
Cat.No: T76957
Synonym: LymphoStat B
Target: TNF
PI3Kδ-IN-3
Cat.No: T26252
Synonym: TC KHNS 11
Target: PI3K
SB-590885
Cat.No: T2295
Synonym:
Target: Raf
Purvalanol A
Cat.No: T2059
Synonym: NG-60
Target: Apoptosis, CDK, Autophagy
Diflufenican
Cat.No: T21012
Synonym: M&B 38544,吡氟草胺
Target: Others
AP20187
Cat.No: T14299
Synonym: B/B Homodimerizer
Target: Others
Glofitamab
Cat.No: T76685
Synonym: RO7082859,RG 6026,CD20-TCB
Target: Others
Mosunetuzumab
Cat.No: T76692
Synonym: BTCT-4465A
Target: Others
Cat. No. Product Name Target Signaling Pathways
T4038 Ectoine

THP(B),L-Ectoine,四氢甲基嘧啶羧酸

Others; Antibacterial Microbiology/Virology; Others
Ectoine (L-Ectoine) 是生活在极其恶劣环境中的细菌所产生的氨基酸衍生物,是一种天然的细胞保护剂。它具有良好的安全性,可研究过敏性鼻炎。它用作渗透调节相容性溶质,可增加皮肤表面的水合作用并稳定脂质层,常用于皮肤护理。
T13818 Phytohemagglutinin

PHA-M,植物血球凝集素,PHA,植物血凝素

Apoptosis Apoptosis
Phytohemagglutinin (PHA-M) 是一种普通豆菜豆的主要种子凝集素,聚集在子叶的薄壁细胞中。它是一种 T 细胞激活剂,能够刺激人单核白细胞,可诱导 ChAT mRNA 表达,增强 ACh 合成。
TN1019 Beta-mangostin

β-Mangostin,beta-倒捻子素

Apoptosis; Antibacterial; Parasite Apoptosis; Microbiology/Virology
Beta-mangostin (β-Mangostin) 是存在 Cratoxylum arborescens 中的一种氧杂蒽酮类天然产物,有抗癌和抗菌活性,对结核分枝杆菌的 MIC 值为 6.25 μg/mL。它在体外有抗疟活性,对恶性疟原虫的 IC50值为 3.00 μg/mL。
TN1471 Cassiaside C

决明子苷C,Toralactone 9-O-β-D-gentiobioside

Others; Endogenous Metabolite Metabolism; Others
Cassiaside C (Toralactone 9-O-β-D-gentiobioside) 是一种萘酚类化合物,从决明子种子中分离得到,对晚期糖基化终产物 (AGE) 的形成具有抑制作用。
T6S1780 Protosappanin B

原苏木素B,Q-100961,FT-0689654

Apoptosis Apoptosis
Protosappanin B (Q-100961) 是从苏木中提取的一种多酚类天然产物,具有抗肿瘤作用。它通过激活 MDM2 依赖性泛素化过程诱导 p53 蛋白降解。它显著提高细胞活力,抑制细胞凋亡并上调生长相关蛋白 43 的表达。
T5S1261 Methylophiopogonanone B

Ras GPCR/G Protein; MAPK
Methylophiopogonanone B 是一种高异二氢黄酮,提取自麦冬的根,抗氧化能力强,它通过 Rho 信号传导途径及增加 GTP-Rho 发挥效果。它能够重组肌动蛋白细胞骨架,使细胞形态(如树突收缩、应力纤维形成)发生变化。
TN3628 Chamaejasmenin B

Others Others
Chamaejasmenin B 是一种从 Stellera chamaejasme L 中分离得到的化合物。Chamaejasmenin B 具有抗癌和抗肿瘤活性,可抑制癌细胞迁移和侵袭,抑制肿瘤转移。Chamaejasmenin B 可用于研究如乳腺癌类的癌症。
TMS0879 Asiaticoside B

积雪草苷 B,积雪草苷B

Others Others
Asiaticoside B 是一种从类叶升麻中分离得到的三萜糖苷,具有抗肿瘤作用。 它对 HepG2 和 MCF-7 癌细胞系具有显著的细胞毒性。
T5780 HYPOCRELLIN B

Apoptosis; Parasite; Antifungal Apoptosis; Microbiology/Virology
Hypocrellin B 是从真菌Hypocrella bambusae 和Shiraia bambusicola 中分离得到的一种感光颜料,可用于癌症光动力研究。它是一个凋亡诱导剂,还拥有抗菌和抗利什曼活性。
T1067 Amphotericin B

NSC 527017,两性霉素B

Antibiotic; Antifungal Microbiology/Virology
Amphotericin B (NSC-527017) 是一种多烯类抗真菌剂,对许多真菌物种具有广谱活性。Amphotericin B 不可逆地结合麦角甾醇,破坏细胞膜完整性,从而起到抗真菌活性。
T6S1917 Schisandrol B

Gomisin A,TJN-101,Besigomsin,五味子醇乙,Gamma-Schisandrin,戈米辛A,Schizandrol B,Wuweizi alcohol-B

P450; Reactive Oxygen Species; Autophagy Autophagy; Immunology/Inflammation; Metabolism; NF-κB
Schisandrol B (Besigomsin) 是华中五味子的主要活性成分,具有保肝、抗炎、抗糖尿病和抗氧化的作用。它抑制活性氧的产生,也抑制 P-糖蛋白和CYP3A 的活性。
TN1805 Isosilybin B

Apoptosis; Androgen Receptor Apoptosis; Endocrinology/Hormones
Isosilybin B 是一种从水飞蓟中提取的黄酮木脂素,具有抗前列腺癌 (PCA) 活性,对癌细胞增殖有抑制作用,促使 G1 期阻滞和凋亡。Isosilybin B 诱导雄激素受体降解。
T4S0931 Pseudolaric acid A

土槿皮甲酸,NSC 615487,土荆皮甲酸

Others; Antifungal Microbiology/Virology; Others
Pseudolaric acid A (NSC 615487) 是从Pseudolarix kaempferi 分离的一种二萜酸,具有抗真菌、抗受精和细胞毒性活性。
TN1675 Gardenin B

栀子黄素B

Apoptosis; ROS; Caspase; NO Synthase Apoptosis; Immunology/Inflammation; Proteases/Proteasome
Gardenin B 是从Baccharis scandens 中分离出的一种黄酮类天然产物。它对肺、乳腺、结肠、肝和白血病细胞系以及角质形成细胞具有优异的抗增殖活性。
TN2256 Taccalonolide B

根薯酮内酯B,根薯酮内酯 B

Microtubule Associated Cytoskeletal Signaling
Taccalonolide B 是从广西裂果薯中分离得到的一种微管稳定剂,具有抗肿瘤活性。它抑制 SK-OV-3 细胞的生长,IC50 为 208 nM,在体外对过表达 P-糖蛋白 (Pgp) 和多药耐药蛋白 (MRP7) 的细胞系有效。
T1116 Biotin

Vitamin B7,生物素,D-Biotin,Vitamin H,D-生物素(维生素H)

Biotin (Vitamin H) 属于天然产物,是一种 B 族维生素,具有水溶性。Biotin 参与脂肪酸产生、脂肪和氨基酸代谢以及细胞生长。Biotin 常被用于生物素标记。
TN5254 Wighteone

Erythrinin B,6-Isopentenylgenistein

Antifungal Microbiology/Virology
Wighteone (Erythrinin B) 是一种从 Genista ephedroides 中提取出来的小分子化合物,具有潜在的抗真菌和抗癌活性,对 EGFR L858R/T790M 突变非小细胞肺癌具有抗肿瘤作用。。
T1100 Polymyxin B Sulfate

Aerosporin,硫酸多粘菌素 B,PMB,Polymyxin B sulphate,硫酸多粘菌素B,Polymyxin B sulfate (1404-26-8 free base),Poly-RX

Antibacterial; Antibiotic Microbiology/Virology
Polymyxin B Sulfate (Poly-RX) 是一个阳离子型表面活性剂抗生素剂,能够提高细胞膜的渗透性。
T3900 Emodin-8-glucoside

大黄素-8-β-D-吡喃葡萄糖苷,Emodin glucoside B,Anthraglycoside B

Others Others
Emodin-8-glucoside (Anthraglycoside B) 是从芦荟中分离出的蒽醌衍生物,与 DNA 的小沟结合。它具有保护缺血和再灌注引起的局灶性脑损伤的作用。它直接刺激成骨细胞的细胞增殖和分化。
TN1880 Lucidenic acid B

Lucidenicacid B

Apoptosis; Caspase Apoptosis; Proteases/Proteasome
Lucidenic acid B (Lucidenicacid B) 是从灵芝中提取得到的天然化合物,可诱导caspase-9 和 caspase-3 的活化和 PARP 的裂解,可通过线粒体介导诱导人白血病细胞凋亡 。 Lucidenic acid B通过灭活MAPK / ERK信号转导途径和降低NF-kappaB和AP-1的结合活性来抑制PMA诱导的人肝癌细胞侵袭。。Lucidenic acid B 对细胞周期和坏死细胞没有影响。
T4S0350 Licochalcone B

甘草查尔酮 B,甘草查尔酮B

Beta Amyloid; Others Neuroscience; Others
Licochalcone B 是从Glycyrrhiza inflate 根中提取的。它能够抑制淀粉样蛋白 β 自聚集作用 (IC50=2.16 μM) ,分解预先形成的 Aβ42原纤维,并通过螯合金属离子抑制金属诱导的 Aβ42聚集。
T5826 Eupalinolide A

HSP Cytoskeletal Signaling; Metabolism
Eupalinolide A 是分离于林泽兰中的一种天然产物,通过抑制 HSF1 与 HSP90 的相互作用,激活 HSF1,诱导 HSP70 的表达。它对 A-549、BGC-823、SMMC-7721 和 HL-60 肿瘤细胞系具有强大的细胞毒性。
T6564 Leupeptin Hemisulfate

亮肽素

Serine Protease; Cysteine Protease Proteases/Proteasome
Leupeptin hemisulfate 是一种蛋白酶抑制剂,具有细胞膜渗透性、可逆性、竞争性和口服活性。Leupeptin hemisulfate 可以抑制 Cathepsin B、Cathepsin H、Cathepsin L 的活性,阻断两性溶酶体的融合。Leupeptin hemisulfate 还具有抗炎活性。
TN1620 Eriocalyxin B

毛萼乙素

Apoptosis; cAMP; NF-κB; STAT Apoptosis; GPCR/G Protein; JAK/STAT signaling; NF-κB; Stem Cells
Eriocalyxin B 是从中草药枇杷素中分离得到的一种二萜类天然产物,可诱导细胞凋亡,具有抗癌和抗炎作用。
T7028 Licochalcone C

LICOCHALCONEC,甘草查尔酮C

Phosphatase; Antioxidant; Glucosidase Metabolism; oxidation-reduction
Licochalcone C (LICOCHALCONEC) 能够抑制 α-葡萄糖苷酶,其对 α-葡萄糖苷酶的 IC50 <100 nM,对蛋白酪氨酸磷酸酶 1B 的 IC50=92.43 μM 。
T1257 Bestatin

Ubenimex,乌苯美司

Others; Aminopeptidase; Antibacterial; Antibiotic; LTR Immunology/Inflammation; Metabolism; Microbiology/Virology; Others
Bestatin (Ubenimex) 是 CD13 (Aminopeptidase N)/APN 和 leukotriene A4 hydrolase 抑制剂,可用于癌症研究。
T3S2325 Ardisiacrispin A

百两金素,Saxifragifolin B,LTS-4,Deglucocyclamin

HSV Microbiology/Virology
Ardisiacrispin A (Deglucocyclamin) 是一种常见的三萜皂苷,来自于紫金牛属物种。 它与来自紫金牛属的 A. crenata 中的一些三萜皂苷具有相似的生物学特性,如对肿瘤细胞具有细胞毒活性、免疫调节和抗病毒活性。
TN1564 Delphinidin 3-glucoside chloride

Delphinidin-3-O-glucoside chloride

Apoptosis; EGFR Angiogenesis; Apoptosis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
Delphinidin 3-glucoside chloride (Delphinidin-3-O-glucoside chloride) 是从 Hibiscus sabdariffa 提取物中发现的膳食酚类物质。Delphinidin 3-glucoside chloride 具有抗氧化活性,可诱导 B 细胞慢性淋巴细胞性白血病 (B CLL) 的促凋亡作用,抑制 EGFR,抑制血小板聚集。Delphinidin 3-glucoside chloride 具有抗肿瘤活性,通过调节 pAKT/IRF1/HOTAIR 通路发挥作用。
T0798 Triamcinolone

Fluoxyprednisolone,曲安西龙,Aristocort,Rodinolone

Glucocorticoid Receptor; COX Endocrinology/Hormones; Immunology/Inflammation; Neuroscience
Triamcinolone (Aristocort) 是一种皮质类固醇激素受体激动剂,也是一种合成的长效糖皮质激素,具有抗炎活性。
T5S0527 Rhodojaponin III

闹羊花素 Ⅲ,闹羊花毒素III

Others Others
Rhodojaponin III 是二萜类化合物,提取于Rhododendron molle 叶子,具有抗炎作用。
TN2063 Physalin B

NSC-287088

Apoptosis; NF-κB; Akt; PI3K; Nrf2; NOD Apoptosis; Cytoskeletal Signaling; Immunology/Inflammation; NF-κB; PI3K/Akt/mTOR signaling
Physalin B 是茄科植物的主要活性化合物之一,具有广泛的生物活性,可用于治疗炎症湿疹和疱疹等疾病。Physalin B 通过激活 PI3K/Akt 通路抑制 NF-κB 和 NLRP3,从而改善脂多糖诱导的急性肺损伤造成的炎症反应。Physalin B 通过激活 Nrf2 通路抑制 PDGF-BB 诱导的 VSMC 增殖、迁移和表型转化。Physalin B 通过抑制 LAP2α-HDAC1 介导的胶质瘤相关癌基因 1 的去乙酰化和肝星状细胞活化来发挥抗肿瘤活性。
T6S1653 Albiflorin

Alibiflorin,芍药内酯苷

Reactive Oxygen Species Immunology/Inflammation; Metabolism; NF-κB
Albiflorin (Alibiflorin) 是一种牡丹根中的主要成分,是一种单萜糖苷。它具有神经保护、抗炎、抗氧化和缓解疼痛作用。
TN1956 Mulberrofuran G

Phosphatase; HBV; Glucosidase Metabolism; Microbiology/Virology
Mulberrofuran G分离自自 Morus alba L.,具有抗乙型肝炎病毒活性,可保护缺血损伤诱导的细胞死亡。Mulberrofuran G 是一种 PTP1B 和 α-葡萄糖苷酶的双重抑制剂,可用于研究阿尔茨海默症。
TN3972 Epimedokoreanin B

Apoptosis; Others; Antibacterial Apoptosis; Microbiology/Virology; Others
Epimedokoreanin B (EKB) 是一种从韩国淫羊藿中分离出的异戊烯化类黄酮,在人非小细胞肺癌(NSCLC)A549和NCI-H292细胞中展现出抗癌活性。Epimedokoreanin B 还具有抗炎和抗菌活性,可有清除 DPPH 自由基的活性,能以剂量依赖的方式抑制 MCF-7 和 HepG2 的增殖。Epimedokoreanin B 能显著抑制 N (δ) -(羧甲基)赖氨酸(CML)和 N (Ï) -(羧甲基)精氨酸(CMA)的形成,可通过抑制高级糖化终产物(AGEs)预防糖尿病的临床并发症。
T3S1612 kuwanon G

桑黄酮G,Moracenin B,桑黄酮 G,Kuwanone G

Phosphatase; Antibacterial; Bombesin Receptor; AChR; AChE; Glucosidase GPCR/G Protein; Metabolism; Microbiology/Virology; Neuroscience
Kuwanon G (Moracenin B) 是一种从桑树中得到的黄酮类蛙皮素受体拮抗剂,具有杀菌作用。
T6S1256 Ruscogenin

NOS; NF-κB; NOD-like Receptor (NLR) Immunology/Inflammation; NF-κB
Ruscogenin 是一种重要甾体皂苷元,提取自麦冬。它能够抑制 TXNIP/NLRP3炎症体激活和 MAPK 途径,改善脑缺血诱导的血脑屏障功能障碍,具有显著抗血栓、抗炎作用。
T5S0734 Desmethoxyyangonin

Desmethoxy yangonin,去甲氧基醉椒素,Demethoxyyangonin,5,6-Dehydrokavain

Others; Monoamine Oxidase Neuroscience; Others
Desmethoxyyangonin (5,6-Dehydrokavain) 是一种MAO-B 可逆性抑制剂。
T1331 Riboflavin phosphate sodium

Riboflavin 5'-phosphate sodium,核黄素磷酸钠(维生素B2),Vitamin B2 Phosphate Sodium Salt,Flavin mononucleotide,FMN,核黄素磷酸钠,FMN-Na,riboflavin-5'-phosphate

Endogenous Metabolite Metabolism
Riboflavin phosphate sodium (FMN) 是 riboflavin 的磷酸钠盐形式,riboflavin 是一种水溶性和必需的微量营养素,是自然产生的维生素B复合物的主要生长促进因子。Riboflavin phosphate sodium 转化为2种辅酶,黄素单核苷酸(FMN)和黄素腺嘌呤二核苷酸(FAD),这两种辅酶通过帮助脂肪、碳水化合物和蛋白质的代谢来产生能量,并且是红细胞形成和呼吸、抗体产生以及调节人体生长和繁殖所必需的。
T5S2343 Acetylshikonin

乙酰紫草素,Acetyl shikonin

Others; P450; AChE Metabolism; Neuroscience; Others
Acetylshikonin 来源于紫草根,具有抗癌、抗炎作用。它是一种 AChE 抑制剂,具有很强的抗凋亡活性。它是一种非选择性的细胞色素 P450抑制剂,对所有 P450 亚型抑制的 IC50值范围为 1.4-4.0 μM。
TN6639 Suspenoidside B

Suspenoidside B possesses strong hepatoprotective activities against the damage in HepG2 cell.
T5768 bruceine B

TNF; Parasite Apoptosis; Microbiology/Virology
Bruceine B 是一种有效的白细胞-内皮细胞粘附抑制剂,可抑制蛋白质和核酸合成。
TN4472 Maackiaflavanone

Others Others
Maackiaflavanone B shows cytotoxic activity with IC(50) value of 7.8 microM against human cancer cell line A375S2.
TN4898 Rauvovertine B

Others Others
Rauvovertine B shows cytotoxicity in vitro against human tumor cell lines.
TN4172 Guajadial B

Topoisomerase DNA Damage/DNA Repair
Guajadial B acts as a Top1 catalytic inhibitor and delays Top1 poison-mediated DNA damage. Guajadial B shows cytotoxicities against five human cancer cell lines, it is the most effective having an IC50 value of 150 nM toward A549 cells.
TN2192 Scutebarbatine B

Others Others
Scutebarbatine B shows weak cytotoxicity with IC50 values ranging from 35.11 to 42.73 μM against K562 cell lines and HL60 cell lines.
TN6591 Cannabisin B

Cannabisin B possesses considerable antiproliferative activity and that it may be utilised as a promising chemopreventive agent against hepatoblastoma disease. It induces autophagic cell death by inhibiting the AKT/mTOR pathway and S phase cell cycle arre
TN5676 Musellarin B

Musellarin B is cytotoxic toward several of the human tumor cell lines (HL-60, SMMC-7721, A-549, MCF-7, and SW480).
TN2076 Pinobanksin

短叶松素

Others Others
Pinobanksin and some of its ester derivatives from Sonoran propolis have apoptotic induction in a B-cell lymphoma cell line.
T27237 Echinocandin B

A-30912A,NSC 287461,A 30912A,A30912A,A22082

Others Others
Echinocandin B is a cyclic hexapeptide echinocandin antibiotic from Aspergillus nidulans var. echinulatus . It attacks the cell wall of fungi by inhibiting beta-1,3-glucan synthesis.
T75569 Xerophilusin B

Others Others
Xerophilusin B 是一种从 Isodon xerophilus 中分离得到的抗癌剂,对食管鳞状细胞癌 (ESCC) 细胞系表现出抗增殖作用,可诱导 G2/M 细胞周期停滞,介导细胞凋亡 apoptosis。
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天然产物

Ectoine
Cat.No: T4038
Synonym: THP(B),L-Ectoine,四氢甲基嘧啶羧酸
Target: Others, Antibacterial
Phytohemagglutinin
Cat.No: T13818
Synonym: PHA-M,植物血球凝集素,PHA,植物血凝素
Target: Apoptosis
Beta-mangostin
Cat.No: TN1019
Synonym: β-Mangostin,beta-倒捻子素
Target: Apoptosis, Antibacterial, Parasite
Cassiaside C
Cat.No: TN1471
Synonym: 决明子苷C,Toralactone 9-O-β-D-gentiobioside
Target: Others, Endogenous Metabolite
Protosappanin B
Cat.No: T6S1780
Synonym: 原苏木素B,Q-100961,FT-0689654
Target: Apoptosis
Methylophiopogonanone B
Cat.No: T5S1261
Synonym:
Target: Ras
Chamaejasmenin B
Cat.No: TN3628
Synonym:
Target: Others
Asiaticoside B
Cat.No: TMS0879
Synonym: 积雪草苷 B,积雪草苷B
Target: Others
HYPOCRELLIN B
Cat.No: T5780
Synonym:
Target: Apoptosis, Parasite, Antifungal
Amphotericin B
Cat.No: T1067
Synonym: NSC 527017,两性霉素B
Target: Antibiotic, Antifungal
Schisandrol B
Cat.No: T6S1917
Synonym: Gomisin A,TJN-101,Besigomsin,五味子醇乙,Gamma-Schisandrin,戈米辛A,Schizandrol B,Wuweizi alcohol-B
Target: P450, Reactive Oxygen Species, Autophagy
Isosilybin B
Cat.No: TN1805
Synonym:
Target: Apoptosis, Androgen Receptor
Pseudolaric acid A
Cat.No: T4S0931
Synonym: 土槿皮甲酸,NSC 615487,土荆皮甲酸
Target: Others, Antifungal
Gardenin B
Cat.No: TN1675
Synonym: 栀子黄素B
Target: Apoptosis, ROS, Caspase, NO Synthase
Taccalonolide B
Cat.No: TN2256
Synonym: 根薯酮内酯B,根薯酮内酯 B
Target: Microtubule Associated
Biotin
Cat.No: T1116
Synonym: Vitamin B7,生物素,D-Biotin,Vitamin H,D-生物素(维生素H)
Target:
Wighteone
Cat.No: TN5254
Synonym: Erythrinin B,6-Isopentenylgenistein
Target: Antifungal
Polymyxin B Sulfate
Cat.No: T1100
Synonym: Aerosporin,硫酸多粘菌素 B,PMB,Polymyxin B sulphate,硫酸多粘菌素B,Polymyxin B sulfate (1404-26-8 free base),Poly-RX
Target: Antibacterial, Antibiotic
Emodin-8-glucoside
Cat.No: T3900
Synonym: 大黄素-8-β-D-吡喃葡萄糖苷,Emodin glucoside B,Anthraglycoside B
Target: Others
Lucidenic acid B
Cat.No: TN1880
Synonym: Lucidenicacid B
Target: Apoptosis, Caspase
Licochalcone B
Cat.No: T4S0350
Synonym: 甘草查尔酮 B,甘草查尔酮B
Target: Beta Amyloid, Others
Eupalinolide A
Cat.No: T5826
Synonym:
Target: HSP
Leupeptin Hemisulfate
Cat.No: T6564
Synonym: 亮肽素
Target: Serine Protease, Cysteine Protease
Eriocalyxin B
Cat.No: TN1620
Synonym: 毛萼乙素
Target: Apoptosis, cAMP, NF-κB, STAT
Licochalcone C
Cat.No: T7028
Synonym: LICOCHALCONEC,甘草查尔酮C
Target: Phosphatase, Antioxidant, Glucosidase
Bestatin
Cat.No: T1257
Synonym: Ubenimex,乌苯美司
Target: Others, Aminopeptidase, Antibacterial, Antibiotic, LTR
Ardisiacrispin A
Cat.No: T3S2325
Synonym: 百两金素,Saxifragifolin B,LTS-4,Deglucocyclamin
Target: HSV
Delphinidin 3-glucoside chloride
Cat.No: TN1564
Synonym: Delphinidin-3-O-glucoside chloride
Target: Apoptosis, EGFR
Triamcinolone
Cat.No: T0798
Synonym: Fluoxyprednisolone,曲安西龙,Aristocort,Rodinolone
Target: Glucocorticoid Receptor, COX
Rhodojaponin III
Cat.No: T5S0527
Synonym: 闹羊花素 Ⅲ,闹羊花毒素III
Target: Others
Physalin B
Cat.No: TN2063
Synonym: NSC-287088
Target: Apoptosis, NF-κB, Akt, PI3K, Nrf2, NOD
Albiflorin
Cat.No: T6S1653
Synonym: Alibiflorin,芍药内酯苷
Target: Reactive Oxygen Species
Mulberrofuran G
Cat.No: TN1956
Synonym:
Target: Phosphatase, HBV, Glucosidase
Epimedokoreanin B
Cat.No: TN3972
Synonym:
Target: Apoptosis, Others, Antibacterial
kuwanon G
Cat.No: T3S1612
Synonym: 桑黄酮G,Moracenin B,桑黄酮 G,Kuwanone G
Target: Phosphatase, Antibacterial, Bombesin Receptor, AChR, AChE, Glucosidase
Ruscogenin
Cat.No: T6S1256
Synonym:
Target: NOS, NF-κB, NOD-like Receptor (NLR)
Desmethoxyyangonin
Cat.No: T5S0734
Synonym: Desmethoxy yangonin,去甲氧基醉椒素,Demethoxyyangonin,5,6-Dehydrokavain
Target: Others, Monoamine Oxidase
Riboflavin phosphate sodium
Cat.No: T1331
Synonym: Riboflavin 5'-phosphate sodium,核黄素磷酸钠(维生素B2),Vitamin B2 Phosphate Sodium Salt,Flavin mononucleotide,FMN,核黄素磷酸钠,FMN-Na,riboflavin-5'-phosphate
Target: Endogenous Metabolite
Acetylshikonin
Cat.No: T5S2343
Synonym: 乙酰紫草素,Acetyl shikonin
Target: Others, P450, AChE
Suspenoidside B
Cat.No: TN6639
Synonym:
Target:
bruceine B
Cat.No: T5768
Synonym:
Target: TNF, Parasite
Maackiaflavanone
Cat.No: TN4472
Synonym:
Target: Others
Rauvovertine B
Cat.No: TN4898
Synonym:
Target: Others
Guajadial B
Cat.No: TN4172
Synonym:
Target: Topoisomerase
Scutebarbatine B
Cat.No: TN2192
Synonym:
Target: Others
Cannabisin B
Cat.No: TN6591
Synonym:
Target:
Musellarin B
Cat.No: TN5676
Synonym:
Target:
Pinobanksin
Cat.No: TN2076
Synonym: 短叶松素
Target: Others
Echinocandin B
Cat.No: T27237
Synonym: A-30912A,NSC 287461,A 30912A,A30912A,A22082
Target: Others
Xerophilusin B
Cat.No: T75569
Synonym:
Target: Others
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Cat. No. Product Name Species Expression System
TMPY-02700 BCL2 Protein, Human, Recombinant (His)

Bcl-2,PPP1R50,B-cell CLL/lymphoma...

Human E. coli
BCL2 (B-cell leukemia/lymphoma 2, N-Histidine-tagged), also known as Bcl-2, belongs to the Bcl-2 family. Bcl-2 family proteins regulate and contribute to programmed cell death or apoptosis. It is a large protein family and all members contain at least one of four BH (bcl-2 homology) domains. Certain members such as Bcl-2, Bcl-xl and Mcl1 are anti-apoptotic, whilst others are pro-apoptotic. Most Bcl-2 family members contain a C-terminal transmembrane domain that functions to target these proteins...
TMPJ-00113 CD79B Protein, Human, Recombinant (hFc)

Immunoglobulin-Associated B29 Protein,...

Human HEK293 Cells
CD79B Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 45-65 KDa and the accession number is P40259.
TMPJ-01391 BAFF/TNFSF13B Protein, Mouse, Recombinant (mFc)

TALL-1,Dendritic cell-derived TNF-like molecule,

Mouse HEK293 Cells
BAFF/TNFSF13B Protein, Mouse, Recombinant (mFc) is expressed in HEK293 mammalian cells with N-mFc tag. The predicted molecular weight is 45-60 KDa and the accession number is Q9WU72.
TMPY-03630 MZB1/PERP1 Protein, Human, Recombinant (His)

MEDA-7,marginal zone B and B1 cell

Human HEK293 Cells
MZB1/PERP1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 19.4 kDa and the accession number is Q8WU39-1.
TMPH-02271 BTK Protein, Human, Recombinant (His)

BPK,AGMX1,ATK,B-cell progenitor k...

Human Baculovirus Insect Cells
Non-receptor tyrosine kinase indispensable for B lymphocyte development, differentiation and signaling. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation. After BCR engagement and activation at the plasma membrane, phosphorylates PLCG2 at several sites, igniting the downstream signaling pathway through calcium mobilization, followed by activation of the protein kinase C (PKC) family members. PLCG2 phosphorylation is performed in...
TMPJ-00035 IL-4 Protein, Human, Recombinant (His)

Pitrakinra,Binetrakin,B-Cell Stim...

Human HEK293 Cells
IL-4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 18 KDa and the accession number is P05112.
TMPJ-00258 TGF beta 2 Protein, Human, Recombinant

Glioblastoma-derived T-cell suppressor fac...

Human HEK293 Cells
Transforming growth factor beta-2 (TGF-β2) is a secreted protein which belongs to the TGF-beta family. It is known as a cytokine that performs many cellular functions and has a vital role during embryonic development. The precursor is cleaved into mature TGF-beta-2 and LAP, which remains non-covalently linked to mature TGF-beta-2 rendering it inactive. It is an extracellular glycosylated protein. It is known to suppress the effects of interleukin dependent T-cell tumors. Defects in TGFB2 may be...
TMPJ-00261 TGF beta 2 Protein, Mouse/Rat, Recombinant

transforming growth factor β-2,BSC-1 cell ...

Mouse,Rat HEK293 Cells
Transforming growth factor beta 2 (TGF-β2) is a member of TGF-beta superfamily that shares a characteristic cysteine knot structure. Mice with TGF-β2 gene deletion show defects in development of cardiac, lung, craniofacial, limb, spinal column, eye, inner ear and urogenital systems. All TGF-β isoforms signal via the same heteromeric receptor complex, consisting of a ligand binding TGF-β receptor type II (TβR-II), and a TGF-β receptor type I (TβR-I). Signal transduction from the receptor to the n...
TMPJ-01070 CD83 Protein, Human, Recombinant (hFc)

hCD83,B-cell activation protein,CD_antigen...

Human HEK293 Cells
CD83 antigen is a single-pass type I membrane protein which contains one Ig-like V-type (immunoglobulin-like) domain. CD83 is expressed by activated lymphocytes, Langerhans cells and interdigitating reticulum cells. It contains one Ig-like V-type (immunoglobulin-like) domain. , the soluble CD83 has the opposite effect and has an immune inhibitory capacity. Due to its immune inhibitory function, CD83 may play a significant role in antigen presentation or the cellular interactions that follow lymp...
TMPJ-00968 NAMPT Protein, Human, Recombinant (His)

PBEF,PBEF1,Nicotinamide phosphorib

Human E. coli
Pre-B cell colony enhancing factor (PBEF) was originally identified as a cytokine that potentiated the clonal expansion and differentiation of pre-B cells, but it is also acknowledged to be the ubiquitous intracellular enzyme nicotinamide phosphoribosyltranferase (NAMPT) and the adipokine “visfatin”. PBEF is constitutively expressed in the fetal membranes where its greatest expression is in the amnion. It has intracellular and extracellular forms. Most of the intracellular functions of PBEF are ...
TMPJ-00112 CD79B Protein, Human, Recombinant (His & Avi), Biotinylated

Immunoglobulin-Associated B29 Protein,...

Human HEK293 Cells
CD79B Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-6xHis-Avi tag. The predicted molecular weight is 30-40 KDa and the accession number is P40259.
TMPJ-00898 CD72 Protein, Human, Recombinant (Trx & His)

Lyb-2,B-Cell Differentiation Anti...

Human E. coli
B-Cell Differentiation Antigen CD72 (CD72) is a single-pass type II membrane protein. CD72 exists as a disulfide-linked homodimer and contains one C-type lectin domain. CD72 is expressed on B lineage cells, NK cells, monocytes, dendritic cells, and mast cells. CD72 is a ligand for CD5. CD72 associates with CD5, interacts with PTPN6/SHP-1 and plays a role in B-cell proliferation and differentiation. CD72 associates with CD79A in the B cell antigen receptor (BCR) complex following antigen stimulat...
TMPJ-00118 CD79B Protein, Rhesus macaque, Recombinant (hFc)

B-Cell Antigen Receptor Complex-Associated...

Rhesus HEK293 Cells
CD79B Protein, Rhesus macaque, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 50-60 KDa and the accession number is H9ZFT8.
TMPJ-00862 CD79B Protein, Mouse, Recombinant (hFc)

Ig-Beta,B-Cell-Specific Glycoprot...

Mouse HEK293 Cells
CD79B Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 50-65 KDa and the accession number is P15530.
TMPY-02507 BCAM Protein, Mouse, Recombinant (His)

Lu,1200005K12Rik,B-CAM,Gplu,basal cell...

Mouse HEK293 Cells
BCAM Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 58.3 kDa and the accession number is Q9R069.
TMPY-02455 BCAM Protein, Mouse, Recombinant (hFc)

1200005K12Rik,basal cell adhesion molecule...

Mouse HEK293 Cells
BCAM Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 84 kDa and the accession number is Q9R069.
TMPJ-00444 Siglec-2/CD22 Protein, Mouse, Recombinant (aa 22-702, His)

CD22 antigenMGC130020,B-cell receptor CD22...

Mouse HEK293 Cells
Siglec-2/CD22 Protein, Mouse, Recombinant (aa 22-702, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 100-120 KDa and the accession number is AAA02562.1.
TMPJ-00178 BAFF/TNFSF13B Protein, Human, Recombinant (His)

B lymphocyte stimulator,TNF- and APOL-related leuko...

Human HEK293 Cells
BAFF/TNFSF13B Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with N-6xHis tag. The predicted molecular weight is 22 KDa and the accession number is Q9Y275.
TMPJ-00392 Siglec-2/CD22 Protein, Human, Recombinant (His & Avi), Biotinylated

T-cell surface antigen Leu-14,CD22 molecule,CD22,SI...

Human HEK293 Cells
Siglec-2/CD22 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-6xHis-Avi tag. The predicted molecular weight is 110-130 KDa and the accession number is P20273.
TMPJ-00393 Siglec-2/CD22 Protein, Human, Recombinant (hFc)

BL-CAM,SIGLEC2FLJ22814,CD22 antigenMGC130020,sialic...

Human HEK293 Cells
Siglec-2/CD22 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 120-150 KDa and the accession number is P20273.
TMPH-02841 Prohibitin Protein, Mouse, Recombinant (His)

Phb1,B-cell receptor-associated p...

Mouse E. coli
Protein with pleiotropic attributes mediated in a cell-compartment- and tissue-specific manner, which include the plasma membrane-associated cell signaling functions, mitochondrial chaperone, and transcriptional co-regulator of transcription factors in the nucleus. Plays a role in adipose tissue and glucose Homeostasis in a sex-specific manner. Contributes to pulmonary vascular remodeling by accelerating proliferation of pulmonary arterial smooth muscle cells.; In the mitochondria, together with...
TMPJ-00020 IL-5 Protein, Human, Recombinant (His & Avi), Biotinylated

白介素,Eosinophil differentiation factor,B-cell

Human HEK293 Cells
IL-5 is expressed in eosinophils, NK cells, TC2 CD8+ T cells, mast cells, CD45+ CD4+ T cells, gamma delta T cells and IL-1 beta activated endothelial cells. IL-5 acts as a growth and differentiation factor for both B cells and eosinophils. Relative to B cells, IL-5 appears to induce the differentiation of activated conventional B-2 cells into Ig-secreting cells. In addition, it induces the growth of B-1 progenitors as well as IgM production by B-1 cells.IL-5 appears to perform a number of functi...
TMPJ-01446 BCMA/TNFRSF17 Protein, Cynomolgus, Recombinant (His)

B-cell maturation protein,CD269,B...

Cynomolgus HEK293 Cells
BCMA/TNFRSF17 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 12 and 15-20 KDa and the accession number is G7Q0I4.
TMPJ-00329 CD19 Protein, Rhesus macaque, Recombinant (hFc)

B-Lymphocyte Antigen CD19,CD19,Differentiation Anti...

Rhesus HEK293 Cells
CD19 is a single-pass type I membrane protein containing 2 Ig-like C2-type (immunoglobulin-like) domains. CD19 is expressed on follicular dendritic cells and B cells. In fact, it is present on B cells from earliest recognizable B-lineage cells during development to B-cell blasts but is lost on maturation to plasma cells. CD19 primarily acts as a B cell co-receptor in conjunction with CD21 and CD81. Upon activation, the cytoplasmic tail of CD19 becomes phosphorylated, which leads to binding by Sr...
TMPJ-01434 BCMA/TNFRSF17 Protein, Cynomolgus, Recombinant (hFc)

Bcma,Tnfrsf17,B-cell maturation p...

Cynomolgus HEK293 Cells
BCMA/TNFRSF17 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 38-45 KDa and the accession number is G7Q0I4.
TMPJ-00066 BCMA/TNFRSF17 Protein, Human, Recombinant (His & Flag)

Tumor necrosis factor receptor superfamily member 1...

Human HEK293 Cells
B cell maturation antigen (BCMA) is a member of the TNF receptor superfamily. It has been designated TNFRSF17. Mouse BCMA is a 185 amino acid (aa) protein consisting of a 49 aa extracellular domain, a 23 aa transmembrane domain, and a 113 aa intracellular domain. BCMA is a type III membrane protein containing one extracellular cysteine rich domain. Within the TNFRSF, it shares the highest homology with TACI. BCMA and TACI have both been shown to bind to APRIL and BAFF, members of the TNF ligand ...
TMPY-02191 BLNK Protein, Human, Recombinant (His)

BLNK-S,bca,SLP-65,B-cell...

Human HEK293 Cells
B-cell linker protein, also known as B-cell adapter containing a SH2 domain protein, B-cell adapter containing a Src homology 2 domain protein, Cytoplasmic adapter protein, Src homology 2 domain-containing leukocyte protein of 65 kDa, SLP-65 and BLNK, is a cytoplasm and cell membrane protein which contains oneSH2 domain. BLNK is expressed in B-cell lineage and fibroblast cell lines. Highest levels of expression is in the spleen, with lower levels in the liver, kidney, pancreas, small inte...
TMPY-01119 MZB1/PERP1 Protein, Human, Recombinant (hFc)

PACAP,marginal zone B and B1 cell...

Human HEK293 Cells
MZB1/PERP1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 44.9 kDa and the accession number is Q8WU39-1.
TMPH-01824 PAX5 Protein, Human, Recombinant (His & Myc)

Paired box protein Pax-5,B-cell-s...

Human E. coli
PAX5 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 47.2 kDa and the accession number is Q02548.
TMPY-02430 BCL6 Protein, Human, Recombinant (aa 1-150, His & Trx)

BCL5,ZNF51,B-cell CLL/lymphoma 6,...

Human E. coli
The protein encoded by this gene is an evolutionarily conserved 95-kDa protein containing six C-terminal zinc-finger motifs and an N-terminal POZ domain. It has been reported that BCL-6 is present in DNA-binding complexes in nuclear extracts from various B-cell lines. There are many relationships between non-Hodgkin's lymphoma, diffuse large cell lymphoma and BCL6’s translocations. BCL6 can repress transcription from promoters linked to its DNA target sequence and this activity is dependent upon...
TMPH-03761 NAMPT Protein, Mouse, Recombinant (HA & His)

Nicotinamide phosphoribosyltransferase,Visfatin,Nam...

Mouse E. coli
NAMPT Protein, Mouse, Recombinant (HA & His) is expressed in E. coli expression system with N-6xHis and C-HA tag. The predicted molecular weight is 60.6 kDa and the accession number is Q99KQ4.
TMPH-03499 IL-4 Protein, Sheep, Recombinant (His)

Interleukin-4,B-cell stimulatory factor 1,...

Sheep P. pastoris (Yeast)
IL-4 Protein, Sheep, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 14.6 kDa and the accession number is P30368.
TMPH-02387 IL-4 Protein, Lama glama, Recombinant (His)

B-cell stimulatory factor 1,Lymphocyte sti...

Lama glama P. pastoris (Yeast)
IL-4 Protein, Lama glama, Recombinant (His) is expressed in yeast with C-6xHis tag. The predicted molecular weight is 13.8 kDa and the accession number is Q865X5.
TMPH-02757 LILRB3 Protein, Mouse, Recombinant (aa 25-642, His)

Paired immunoglobulin-like receptor B,Lilr...

Mouse HEK293 Cells
May act as receptor for class I MHC antigens. Becomes activated upon coligation of LILRB3 and immune receptors, such as FCGR2B and the B-cell receptor. Down-regulates antigen-induced B-cell activation by recruiting phosphatases to its immunoreceptor tyrosine-based inhibitor motifs (ITIM). LILRB3 Protein, Mouse, Recombinant (aa 25-642, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 70.8 kDa and the accession number is P97484.
TMPH-02457 IL-4 Protein, Mesocricetus auratus, Recombinant (His)

Lymphocyte stimulatory factor 1,B-cell sti...

Mesocricetus auratus P. pastoris (Yeast)
IL-4 Protein, Mesocricetus auratus, Recombinant (His) is expressed in yeast with C-6xHis tag. The predicted molecular weight is 16.3 kDa and the accession number is Q60440.
TMPJ-00770 Granzyme B/GZMB Protein, Mouse, Recombinant (His)

Gzmb,Cytotoxic cell protease 1,Fragmentin-...

Mouse HEK293 Cells
Granzyme B(GZMB) contains 1 peptidase S1 domain and belongs to the peptidase S1 family. This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp and seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. The protein cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
TMPH-01001 BCL10 Protein, Human, Recombinant (His & SUMO)

B-cell lymphoma/leukemia 10,cCARMEN,hCLAP,...

Human E. coli
Plays a key role in both adaptive and innate immune signaling by bridging CARD domain-containing proteins to immune activation. Acts by channeling adaptive and innate immune signaling downstream of CARD domain-containing proteins CARD9, CARD11 and CARD14 to activate NF-kappa-B and MAP kinase p38 (MAPK11, MAPK12, MAPK13 and/or MAPK14) pathways which stimulate expression of genes encoding pro-inflammatory cytokines and chemokines. Recruited by activated CARD domain-containing proteins: homooligome...
TMPH-02810 NAMPT Protein, Mouse, Recombinant (His)

Pre-B-cell colony-enhancing factor 1 homol...

Mouse P. pastoris (Yeast)
NAMPT Protein, Mouse, Recombinant (His) is expressed in yeast with N-10xHis tag. The predicted molecular weight is 57.9 kDa and the accession number is Q99KQ4.
TMPH-03498 IL-4 Protein, Sheep, Recombinant (B2M & His & Myc)

B-cell stimulatory factor 1,Lymphocyte sti...

Sheep E. coli
IL-4 Protein, Sheep, Recombinant (B2M & His & Myc) is expressed in E. coli expression system with N-10XHis-B2M and C-Myc tag. The predicted molecular weight is 29.6 kDa and the accession number is P30368.
TMPH-03760 NAMPT Protein, Mouse, Recombinant

Visfatin,Pre-B-cell colony-enhancing facto...

Mouse E. coli
NAMPT Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 55.6 kDa and the accession number is Q99KQ4.
TMPJ-01095 CD161 Protein, Human, Recombinant (N-hFc)

Killer cell lectin-like receptor subfamily...

Human HEK293 Cells
CD161 Protein, Human, Recombinant (N-hFc) is expressed in HEK293 mammalian cells with N-Fc tag. The predicted molecular weight is 55-70 KDa and the accession number is Q12918.
TMPJ-01094 CD161 Protein, Human, Recombinant (C-hFc)

Killer cell lectin-like receptor subfamily...

Human HEK293 Cells
CD161 Protein, Human, Recombinant (C-hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 55-70 KDa and the accession number is Q12918.
TMPH-00999 BCL6 Protein, Human, Recombinant (His)

BCL-5,B-cell lymphoma 5 protein,<...

Human E. coli
BCL6 Protein, Human, Recombinant (His) is expressed in E. coli.
TMPJ-00177 BAFF/TNFSF13B Protein, Human, Recombinant (Avi & hFc), Biotinylated

BAFF,Dendritic cell-derived TNF-like molec...

Human HEK293 Cells
B-cell activating factor (BAFF), also known as BLyS, TALL-1, THANK, and TNFSF13B, is a transmembrane glycoprotein in the TNF ligand superfamily. BAFF is a cytokine and serves as a ligand for receptors TNFRSF13B (TACI), TNFRSF17 (BCMA), and TNFRSF13C (BAFFR). BAFF can promotes the survival, proliferation and maturation of B lymphocytes, which are key elements in the pathogenesis of systemic lupus erythematosus (SLE). This cytokine is encoded on TNFSF13B gene, and diverse single-nucleotide polymor...
TMPH-01000 BCL6 Protein, Human, Recombinant

ZNF51,LAZ3,ZBTB27,Zinc finger protein 51,<...

Human E. coli
BCL6 Protein, Human, Recombinant is expressed in E. coli.
TMPJ-00952 SDF-1/CXCL12 Protein, Mouse, Recombinant

Sdf1,C-X-C motif chemokine 12,Thymic lymphoma cell-...

Mouse E. coli
Mouse Cxcl12 is a secreted and highly conserved protein which belongs to the intercrine alpha (chemokine CxC) family.CXCL12 is widely expressed in various organs including brain, kidney, skeletal muscle, heart, liver, and lymphoid organs. Cxcl12 activates the C-X-C chemokine receptor CXCR4 to induce a rapid and transient rise in the level of intracellular calcium ions and chemotaxis. It also binds to atypical chemokine receptor ACKR3 which activates the beta-arrestin pathway and acts as a scaven...
TMPJ-00634 CD40 Protein, Cynomolgus, Recombinant (His)

CDw40,TNFRSF5,B-Cell Surface Antigen CD40,...

Cynomolgus HEK293 Cells
CD40 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 28-30 KDa and the accession number is G7PG38.
TMPJ-00092 CD8 beta Protein, Human, Recombinant (His)

T-Cell Surface Glycoprotein CD8 Beta Chain...

Human HEK293 Cells
T-Cell Surface Glycoprotein CD8β Chain (CD8 Antigen) is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. CD8 Antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha a...
TMPJ-01420 CD40 Protein, Cynomolgus, Recombinant (hFc)

Tumor Necrosis Factor Receptor Superfamily member 5...

Cynomolgus HEK293 Cells
CD40 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 48-70 KDa and the accession number is XP_005569275.1.
TMPH-01359 CCND1 Protein, Human, Recombinant (His)

CCND1,BCL-1,B-cell lymphoma 1 pro...

Human E. coli
CCND1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 37.7 kDa and the accession number is P24385.
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重组蛋白

BCL2 Protein, Human, Recombinant (His)
Cat.No: TMPY-02700
Species: Human
Expression System: E. coli
CD79B Protein, Human, Recombinant (hFc)
Cat.No: TMPJ-00113
Species: Human
Expression System: HEK293 Cells
BAFF/TNFSF13B Protein, Mouse, Recombinant (mFc)
Cat.No: TMPJ-01391
Species: Mouse
Expression System: HEK293 Cells
MZB1/PERP1 Protein, Human, Recombinant (His)
Cat.No: TMPY-03630
Species: Human
Expression System: HEK293 Cells
BTK Protein, Human, Recombinant (His)
Cat.No: TMPH-02271
Species: Human
Expression System: Baculovirus Insect Cells
IL-4 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00035
Species: Human
Expression System: HEK293 Cells
TGF beta 2 Protein, Human, Recombinant
Cat.No: TMPJ-00258
Species: Human
Expression System: HEK293 Cells
TGF beta 2 Protein, Mouse/Rat, Recombinant
Cat.No: TMPJ-00261
Species: Mouse,Rat
Expression System: HEK293 Cells
CD83 Protein, Human, Recombinant (hFc)
Cat.No: TMPJ-01070
Species: Human
Expression System: HEK293 Cells
NAMPT Protein, Human, Recombinant (His)
Cat.No: TMPJ-00968
Species: Human
Expression System: E. coli
CD79B Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPJ-00112
Species: Human
Expression System: HEK293 Cells
CD72 Protein, Human, Recombinant (Trx & His)
Cat.No: TMPJ-00898
Species: Human
Expression System: E. coli
CD79B Protein, Rhesus macaque, Recombinant (hFc)
Cat.No: TMPJ-00118
Species: Rhesus
Expression System: HEK293 Cells
CD79B Protein, Mouse, Recombinant (hFc)
Cat.No: TMPJ-00862
Species: Mouse
Expression System: HEK293 Cells
BCAM Protein, Mouse, Recombinant (His)
Cat.No: TMPY-02507
Species: Mouse
Expression System: HEK293 Cells
BCAM Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-02455
Species: Mouse
Expression System: HEK293 Cells
Siglec-2/CD22 Protein, Mouse, Recombinant (aa 22-702, His)
Cat.No: TMPJ-00444
Species: Mouse
Expression System: HEK293 Cells
BAFF/TNFSF13B Protein, Human, Recombinant (His)
Cat.No: TMPJ-00178
Species: Human
Expression System: HEK293 Cells
Siglec-2/CD22 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPJ-00392
Species: Human
Expression System: HEK293 Cells
Siglec-2/CD22 Protein, Human, Recombinant (hFc)
Cat.No: TMPJ-00393
Species: Human
Expression System: HEK293 Cells
Prohibitin Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02841
Species: Mouse
Expression System: E. coli
IL-5 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPJ-00020
Species: Human
Expression System: HEK293 Cells
BCMA/TNFRSF17 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPJ-01446
Species: Cynomolgus
Expression System: HEK293 Cells
CD19 Protein, Rhesus macaque, Recombinant (hFc)
Cat.No: TMPJ-00329
Species: Rhesus
Expression System: HEK293 Cells
BCMA/TNFRSF17 Protein, Cynomolgus, Recombinant (hFc)
Cat.No: TMPJ-01434
Species: Cynomolgus
Expression System: HEK293 Cells
BCMA/TNFRSF17 Protein, Human, Recombinant (His & Flag)
Cat.No: TMPJ-00066
Species: Human
Expression System: HEK293 Cells
BLNK Protein, Human, Recombinant (His)
Cat.No: TMPY-02191
Species: Human
Expression System: HEK293 Cells
MZB1/PERP1 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-01119
Species: Human
Expression System: HEK293 Cells
PAX5 Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-01824
Species: Human
Expression System: E. coli
BCL6 Protein, Human, Recombinant (aa 1-150, His & Trx)
Cat.No: TMPY-02430
Species: Human
Expression System: E. coli
NAMPT Protein, Mouse, Recombinant (HA & His)
Cat.No: TMPH-03761
Species: Mouse
Expression System: E. coli
IL-4 Protein, Sheep, Recombinant (His)
Cat.No: TMPH-03499
Species: Sheep
Expression System: P. pastoris (Yeast)
IL-4 Protein, Lama glama, Recombinant (His)
Cat.No: TMPH-02387
Species: Lama glama
Expression System: P. pastoris (Yeast)
LILRB3 Protein, Mouse, Recombinant (aa 25-642, His)
Cat.No: TMPH-02757
Species: Mouse
Expression System: HEK293 Cells
IL-4 Protein, Mesocricetus auratus, Recombinant (His)
Cat.No: TMPH-02457
Species: Mesocricetus auratus
Expression System: P. pastoris (Yeast)
Granzyme B/GZMB Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00770
Species: Mouse
Expression System: HEK293 Cells
BCL10 Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-01001
Species: Human
Expression System: E. coli
NAMPT Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02810
Species: Mouse
Expression System: P. pastoris (Yeast)
IL-4 Protein, Sheep, Recombinant (B2M & His & Myc)
Cat.No: TMPH-03498
Species: Sheep
Expression System: E. coli
NAMPT Protein, Mouse, Recombinant
Cat.No: TMPH-03760
Species: Mouse
Expression System: E. coli
CD161 Protein, Human, Recombinant (N-hFc)
Cat.No: TMPJ-01095
Species: Human
Expression System: HEK293 Cells
CD161 Protein, Human, Recombinant (C-hFc)
Cat.No: TMPJ-01094
Species: Human
Expression System: HEK293 Cells
BCL6 Protein, Human, Recombinant (His)
Cat.No: TMPH-00999
Species: Human
Expression System: E. coli
BAFF/TNFSF13B Protein, Human, Recombinant (Avi & hFc), Biotinylated
Cat.No: TMPJ-00177
Species: Human
Expression System: HEK293 Cells
BCL6 Protein, Human, Recombinant
Cat.No: TMPH-01000
Species: Human
Expression System: E. coli
SDF-1/CXCL12 Protein, Mouse, Recombinant
Cat.No: TMPJ-00952
Species: Mouse
Expression System: E. coli
CD40 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPJ-00634
Species: Cynomolgus
Expression System: HEK293 Cells
CD8 beta Protein, Human, Recombinant (His)
Cat.No: TMPJ-00092
Species: Human
Expression System: HEK293 Cells
CD40 Protein, Cynomolgus, Recombinant (hFc)
Cat.No: TMPJ-01420
Species: Cynomolgus
Expression System: HEK293 Cells
CCND1 Protein, Human, Recombinant (His)
Cat.No: TMPH-01359
Species: Human
Expression System: E. coli
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Cat. No. Product Name Target Signaling Pathways
TMIH-0065 Acalabrutinib-d4

Acalabrutinib-d4 是 Acalabrutinib 的氘代化合物。Acalabrutinib 的 CAS 号为 1420477-60-6。Acalabrutinib 是一种不可逆的、高效的、具有口服活性、选择性的第二代BTK抑制剂。它与 BTK 的 ATP 结合口袋中的 Cys481 共价结合。它在慢性淋巴细胞性白血病 (CLL) 小鼠模型中显示出强大的靶向作用和功效。
TMIJ-0373 Biotin-d2

Biotin-d2 是 Biotin 的氘代化合物。Biotin 的 CAS 号为 58-85-5。Biotin 是一种水溶性B族维生素,是细胞生长、脂肪酸产生以及脂肪和氨基酸代谢所必需的。
T36903 Rasagiline-13C3 (mesylate)

Rasagiline-13C3 (mesylate)

Rasagiline-13C3is intended for use as an internal standard for the quantification of rasagiline by GC- or LC-MS. Rasagiline is an inhibitor of monoamine oxidase B (MAO-B; IC50= 4.43 nM for the rat brain enzyme).1It is selective for MAO-B over MAO-A (IC50= 412 nM for the rat brain enzyme). It inhibits serum and NGF withdrawal-induced apoptosis of PC12 cells when used at concentrations ranging from 0.01 to 100 μM.2Rasagiline inhibits rat brain MAO-Bin vivo(ED50= 0.1 mg/kg).1It reduces cerebral ede...
T35519 Aflatoxin B2-13C17

Aflatoxin B2-13C17

Aflatoxin B2-13C17(AFB2-13C17) is intended for use as an internal standard for the quantification of AFB2by GC- or LC-MS. AFB2is a mycotoxin that has been found inA. terricola.1It induces hepatic autophagy and apoptosis in broiler chickens when administered at doses of 0.2, 0.4, and 0.8 mg/kg.2AFB2(0.5 and 1 mg/animal) also induces parenchymal cell hyperplasia in rats.3 1.Moubasher, A.H., el-Kady, I.A., and Shoriet, A.Toxigenic Aspergilli isolated from different sources in EgyptAnn. Nutr. Alimen...

同位素标记化合物

Acalabrutinib-d4
Cat.No: TMIH-0065
Synonym:
Target:
Biotin-d2
Cat.No: TMIJ-0373
Synonym:
Target:
Rasagiline-13C3 (mesylate)
Cat.No: T36903
Synonym: Rasagiline-13C3 (mesylate)
Target:
Aflatoxin B2-13C17
Cat.No: T35519
Synonym: Aflatoxin B2-13C17
Target:
TargetMol Loading
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