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Search Results for " avermectin "

Targets Recommended: Others

9

抑制剂 & 化合物

2

天然产物

2

化合物库

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Cat. No.	Product Name
L6500	微生物天然产物库		685 compounds
	685 种微生物来源的生物活性小分子化合物的特有集合，用于高通量、高内涵筛选；
L6620	抗寄生虫天然产物库		253 compounds
	253 个抗寄生虫相关的天然产物集合，是药物开发、药理研究的有效工具；

化合物库

微生物天然产物库

Cat.No: L6500

Compounds: 685

抗寄生虫天然产物库

Cat.No: L6620

Compounds: 253

Cat. No.	Product Name	Target	Signaling Pathways
T64965	Avermectin	Others	Others
	Avermectin 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T64965。
T7605	Avermectin B1a 阿维菌素 B1a,Abamectin B1a,Avamectin B1a	Antibiotic; Parasite	Microbiology/Virology
	Avermectin B1a 是能够使线虫瘫痪的一种抗寄生虫剂。
T35756	Avermectin B1a monosaccharide	Others	Others
	Avermectin B1a monosaccharide is a macrolide anthelmintic and monosaccharide form of avermectin B1a . It is lethal to C. elegans with a minimum active concentration (MAC) value of 0.1 μM. Avermectin B1a monosaccharide also stimulates conductance in isolated shore crab muscle.
T35755	Avermectin B1a aglycone	Others	Others
	Avermectin B1a aglycone is an aglycone form of the anthelmintic and insecticide avermectin B1a . It hyperpolarizes P. crassipes muscle fibers with a minimum active concentration (MAC) value of 0.1 μM. Avermectin B1a aglycone decreases survival of C. elegans (MAC = 0.1 μM). In vivo, avermectin B1a aglycone prevents seizures induced by pentylenetetrazole in mice (ED50 = 43.9 mg/kg) without inducing deficits in rotarod performance.
T21727	Ivermectin B1a	SARS-CoV; Parasite	Microbiology/Virology
	Ivermectin B1a 是 Avermectin B1a 的一种衍生物，是 Ivermectin 的主要成分。Ivermectin 是广谱的抗寄生虫剂。Ivermectin 也是抗 SARS-CoV-2/COVID-19 的候选药物。
T15212	Emamectin Benzoate MK-244,甲胺基阿维菌素苯甲酸盐	Apoptosis; Reactive Oxygen Species; GABA Receptor; Parasite	Apoptosis; Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Neuroscience; NF-κB
	Emamectin Benzoate (MK-244) 是口服有效的神经系统毒物，其通过结合昆虫中的 GABA 受体发挥作用。它是阿维菌素的半合成衍生物之一，具有广谱的杀虫和杀螨活性。它诱导ROS 介导的 DNA 损伤和细胞凋亡。
T5836	Eprinomectin 依普菌素,MK-397	Parasite	Microbiology/Virology
	Eprinomectin (MK-397) 是一种阿维菌素，具有驱虫，杀虫杀螨活性。
T35738	Eprinomectin B1b	Others	Others
	Eprinomectin B1b is a minor component and belongs to the avermectin family of insecticides and anthelmintics.
T85221	Eprinomectin B1a	Others	Others
	Eprinomectin B1a, composing over 90% of the antiparasitic agent eprinomectin, is a primary component alongside eprinomectin B1b, which constitutes less than 10%. This compound is part of the avermectin family, used as insecticides and anthelmintics.

化合物

Cat.No: T64965

Target: Others

Avermectin B1a

Cat.No: T7605

Synonym: 阿维菌素 B1a,Abamectin B1a,Avamectin B1a

Target: Antibiotic, Parasite

Avermectin B1a monosaccharide

Cat.No: T35756

Target: Others

Avermectin B1a aglycone

Cat.No: T35755

Target: Others

Cat.No: T21727

Target: SARS-CoV, Parasite

Emamectin Benzoate

Cat.No: T15212

Synonym: MK-244,甲胺基阿维菌素苯甲酸盐

Target: Apoptosis, Reactive Oxygen Species, GABA Receptor, Parasite

Cat.No: T5836

Synonym: 依普菌素,MK-397

Target: Parasite

Eprinomectin B1b

Cat.No: T35738

Target: Others

Eprinomectin B1a

Cat.No: T85221

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T0956	Avermectin B1 Avermectin B1a-Avermectin B1b mixt.,Abamectin,阿维菌素	Antibiotic; Parasite; Autophagy	Autophagy; Microbiology/Virology
	Avermectin B1 是驱虫杀虫剂。
TN7549	2-epi-Abamectin epi-Avermectin B1a	Others	Others
	2-epi-Abamectin, a degradation product of abamectin, exhibits toxicity towards the two-spotted spider mite in contact assays, possessing an LC50 value of 4 ppm. This indicates it is approximately 100-fold less potent than its precursor, abamectin.

天然产物

Avermectin B1

Cat.No: T0956

Synonym: Avermectin B1a-Avermectin B1b mixt.,Abamectin,阿维菌素

Target: Antibiotic, Parasite, Autophagy

2-epi-Abamectin

Cat.No: TN7549

Synonym: epi-Avermectin B1a

Target: Others

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