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Cat. No. Product Name Species Expression System
TMPH-02687 Granzyme A/GZMA Protein, Mouse, Recombinant (His)

CTLA-3,Granzyme A,Autocrine thymic

Mouse E. coli
Abundant protease in the cytosolic granules of cytotoxic T-cells and NK-cells which activates caspase-independent pyroptosis when delivered into the target cell through the immunological synapse. It cleaves after Lys or Arg. Cleaves APEX1 after 'Lys-31' and destroys its oxidative repair activity. Cleaves the nucleosome assembly protein SET after 'Lys-189', which disrupts its nucleosome assembly activity and allows the SET complex to translocate into the nucleus to nick and degrade the DNA. Granz...

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Granzyme A/GZMA Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02687
Species: Mouse
Expression System: E. coli
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