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Search Results for " aurora-a kinase "

Targets Recommended: Aurora Kinase

54

抑制剂 & 化合物

1

天然产物

141

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T9040	Aurora kinase inhibitor-2 IUN-70219,Aurora Kinase Inhibitor II	Aurora Kinase	Cell Cycle/Checkpoint; Chromatin/Epigenetic
	Aurora kinase inhibitor-2 (IUN-70219) 是一种可渗透细胞的苯胺喹唑啉，可抑制极光激酶的活性，对Aurora A 和Aurora B 的IC50分别为 390 nM 和 240 nM。
T6767	TCS7010 Aurora A Inhibitor I	Apoptosis; Aurora Kinase	Apoptosis; Cell Cycle/Checkpoint; Chromatin/Epigenetic
	TCS7010 (Aurora A Inhibitor I) 是一种选择性的 Aurora A 抑制剂，IC50值为 3.4 nM。
T21981	Phthalazinone pyrazole	Aurora Kinase	Cell Cycle/Checkpoint; Chromatin/Epigenetic
	Phthalazinone pyrazole 是强效、选择性和口服生物可利用的 Aurora-A 激酶抑制剂，IC50值为 0.031 μM。它抑制人胚胎干细胞向肝细胞样细胞分化过程中的上皮间质转化。它还可阻止有丝分裂并随后通过增殖细胞的凋亡抑制肿瘤生长。
T8537	Tripolin A (3E)-3-[(2,5-二羟基苯基)亚甲基]-1,3-二氢-2H-吲哚-2-酮	Aurora Kinase	Cell Cycle/Checkpoint; Chromatin/Epigenetic
	Tripolin A 是一种特异性的非 ATP 竞争性 Aurora A 激酶抑制剂，对Aurora A 和Aurora B 的IC50分别为1.5 μM 和7 μM。
T23426	TC-A 2317 hydrochloride	Others; Aurora Kinase	Cell Cycle/Checkpoint; Chromatin/Epigenetic; Others
	TC-A 2317 hydrochloride 是 Aurora 激酶 A 的抑制剂，Ki 为 1.2 nM，而 Aurora 激酶 B 的 Ki 为 101 nM。 TC-A 2317 hydrochloride 显示出抗肿瘤活性。
T5524	Aurora kinase inhibitor-3 Aurora Kinase Inhibitor III	Aurora Kinase	Cell Cycle/Checkpoint; Chromatin/Epigenetic
	Aurora kinase inhibitor-3 (Aurora Kinase Inhibitor III) 是一种有效的，选择性 Aurora A 激酶抑制剂，IC50为 42 nM。
TQ0059	Ilorasertib ABT-348	VEGFR; FLT; c-RET; PDGFR; Aurora Kinase	Angiogenesis; Apoptosis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; Tyrosine Kinase/Adaptors
	Ilorasertib (ABT-348) 是一种 ATP 竞争性多靶点激酶抑制剂，可抑制 Aurora A、Aurora B 和Aurora C，IC50值为120 nM、7 nM 和1 nM。它还抑制 RET 酪氨酸激酶、PDGFRβ 和 Flt1，IC50为7 nM、3 nM 和 32 nM。
T6068	MK-5108 VX-689,MK5108	Aurora Kinase; Autophagy	Autophagy; Cell Cycle/Checkpoint; Chromatin/Epigenetic
	MK-5108 (VX-689) 是一种高效且特异性的 Aurora-A 激酶抑制剂，IC50 值为 0.064 nM。
T11638	Ilorasertib hydrochloride ABT-348 hydrochloride	Aurora Kinase	Cell Cycle/Checkpoint; Chromatin/Epigenetic
	Ilorasertib hydrochloride (ABT-348 hydrochloride) is an ATP-competitive multitargeted kinase inhibitor, which inhibits Aurora C, Aurora B, and Aurora A (IC50s: 1 nM, 7 nM, 120 nM). It also suppresses RET tyrosine kinase, PDGFRβ, and Flt1 (IC50s: 7 nM, 3 nM, and 32 nM).
T2509	Tozasertib MK-0457,VX 680	Aurora Kinase; Autophagy	Autophagy; Cell Cycle/Checkpoint; Chromatin/Epigenetic
	Tozasertib (MK-0457) 是一种 Aurora A/B/C 激酶抑制剂，Ki 值分别为 0.6、18和4.6 nM。它显示出对 190 多种不同激酶的选择性。
T6126	JNJ-7706621 JNJ 7706621	Apoptosis; CDK; Aurora Kinase	Apoptosis; Cell Cycle/Checkpoint; Chromatin/Epigenetic
	JNJ-7706621 是一种aurora kinase 抑制剂，有效抑制CDK1和CDK2，对CDK1，CDK2，aurora-A 和aurora-B 的IC50值分别为 9 nM，3 nM，11 nM 和 15 nM。
T2611	CCT 137690 CCT137690	Apoptosis; Aurora Kinase	Apoptosis; Cell Cycle/Checkpoint; Chromatin/Epigenetic
	CCT 137690是一种有口服活性的极光激酶抑制剂，对极光激酶A、B 和C 的IC50值分别为15、25 和19 nM。
T50110	CD532	Aurora Kinase	Cell Cycle/Checkpoint; Chromatin/Epigenetic
	CD532 是一种高效的 Aurora A 激酶抑制剂，IC50 值为 45 nM。CD532 可阻断 Aurora A 激酶活性，驱动 MYCN 降解，可以直接与 AURKA 相互作用并诱导整体构象转变。CD532 可用于研究癌症。
T6315	MLN8054	Casein Kinase; PKA; Src; Aurora Kinase	Angiogenesis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; Metabolism; Stem Cells; Tyrosine Kinase/Adaptors
	MLN8054是一种有口服活性的高选择性极光激酶抑制剂，IC50值为4 nM。
T1825	Reversine	Aurora Kinase; Adenosine Receptor; Autophagy	Autophagy; Cell Cycle/Checkpoint; Chromatin/Epigenetic; GPCR/G Protein; Neuroscience
	Reversine 是一种 ATP-竞争性 Aurora kinase 抑制剂，作用于Aurora A、Aurora B 和Aurora C，IC50分别为 400、500 和 400 nM。
T34888	TL12-186 TL12 186,TL12186	CDK; PROTACs	Cell Cycle/Checkpoint; PROTAC
	TL12-186 是一种依赖于 Cereblon 的激酶降解剂，可降解 CDK，BTK，FLT3，Aurora 等激酶。TL12-186 对 CDK2/cyclin A 和 CDK9/cyclin T1 有抑制作用，IC50 分别为 73 和 55 nM。
T2358	ENMD-2076	Apoptosis; VEGFR; FGFR; FLT; c-RET; PDGFR; Src; Aurora Kinase	Angiogenesis; Apoptosis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; Tyrosine Kinase/Adaptors
	ENMD2076是一种多靶点激酶抑制剂，抑制Aurora A、Flt3、KDR/VEGFR2、Flt4/VEGFR3、FGFR1、FGFR2、Src、PDGFRα的IC50值分别为1.86、14、58.2、15.9、92.7、70.8、20.2 and 56.4 nM。
T17267	XL228	IGF-1R; Bcr-Abl; Src; Aurora Kinase	Angiogenesis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
	XL228 是一种多靶点酪氨酸激酶抑制剂，对 Bcr-Abl、Aurora A、IGF-1R、Src 和 Lyn 的 IC50 分别为 5、3.1、1.6、6.1和 2 nM。
T2271	SBE13 Hydrochloride SBE 13 hydrochloride,SBE 13 HCl	Apoptosis; PLK; Autophagy	Apoptosis; Autophagy; Cell Cycle/Checkpoint
	SBE13 Hydrochloride (SBE 13 HCl) 是一种选择性的Plk1抑制剂，IC50值为 0.2 nM，对 Plk2 的IC50>66 μM，Plk3的IC50值为875 nM。
T35570	Chiauranib CS2164,西奥罗尼	c-Fms; VEGFR; FLT; PDGFR; c-Kit; Aurora Kinase	Angiogenesis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; Tyrosine Kinase/Adaptors
	Chiauranib 是一种针对肿瘤血管生成的多靶点抑制剂，具有强大的抗癌作用。 Chiauranib 有效抑制血管生成相关激酶（VEGFR1、VEGFR2、VEGFR3、PDGFRα 和 c-Kit）、有丝分裂相关激酶 Aurora B 和慢性炎症相关激酶 CSF1R，IC50 值范围为 1-9 nM。
T2241	Alisertib MLN 8237,4-[[9-氯-7-(2-氟-6-甲氧基苯基)-5H-嘧啶并[5,4-D][2]苯并氮杂卓-2-基]氨基]-2-甲氧基苯甲酸	Apoptosis; Aurora Kinase; Autophagy	Apoptosis; Autophagy; Cell Cycle/Checkpoint; Chromatin/Epigenetic
	Alisertib (MLN 8237) 是一种 Aurora A 激酶抑制剂 (IC50=1.2 nM)，具有口服活性和选择性。Alisertib 具有抗肿瘤活性，可以诱导细胞凋亡和自噬，诱导细胞周期阻滞。
T4428	CCT241736	FLT; Aurora Kinase	Angiogenesis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; Tyrosine Kinase/Adaptors
	CCT241736 是一种口服生物可利用的双重 FLT3/Aurora 激酶抑制剂，还抑制临床相关的 FLT3 耐药突变体，包括 FLT3-ITD 和 FLT3。它是 CCT137690 的高级类似物，是治疗人类恶性肿瘤的临床前开发候选物。
T68405L	KW-2450 Formate	Tyrosinase	Proteases/Proteasome
	KW-2450 Formate 是一种 IGF-1R/IR酪氨酸激酶抑制剂，具有抗肿瘤作用，通过抑制 Aurora A 和 B 激酶发挥作用。KW-2450 Formate 抑制 TNBC异种移植物的生长，诱导四倍体积累。
T22288	(1E)-CFI-400437 dihydrochloride CFI-400437 dihydrochloride	PLK	Cell Cycle/Checkpoint
	(1E)-CFI-400437 dihydrochloride (CFI-400437 dihydrochloride) 是一种选择性和有效的 polo 样激酶 4 (PLK4) 抑制剂，IC50为 0.6 nM。它还抑制 Aurora A、 Aurora B、 KDR 和 FLT-3，IC50分别为 0.37、0.21、0.48 和 0.18 μM，具有抗增殖活性。
T35328	H-1152 dihydrochloride H-1152 2HCl,H-1152 dihydrochloride	ROCK	Cell Cycle/Checkpoint; Cytoskeletal Signaling; Stem Cells
	H-1152 dihydrochloride (H-1152 2HCl) 是 Rho 相关蛋白激酶 (ROCK) 的特异性抑制剂，IC50 为 12 nM，Ki 为 1.6 nM。 H-1152 dihydrochloride 抑制 PKA、PKC、PKG、Aurora A 和 CaMKII，IC50 值分别为 3.03 μM、5.68 μM、0.360 μM、0.745 μM 和 0.180 μM。
T64338	AKI603 AKI 603,AKI-603	Aurora Kinase	Cell Cycle/Checkpoint; Chromatin/Epigenetic
	AKI603 是一种极光激酶 A 抑制剂，IC50值为 12.3 nM。它对白血病细胞具有很强的抗增殖活性，可用于克服白血病中 BCR-ABL-T315I 耐药性突变。
T63773	Aurora kinase inhibitor-8	Others	Others
	Aurora kinase inhibitor-8 是 Aurora 激酶的高度选择性抑制剂。
T68234	BI-831266	Others	Others
	BI-831266 is a potent and selective Aurora kinase B inhibitor.
T10412	Aurora inhibitor 1	Aurora Kinase	Cell Cycle/Checkpoint; Chromatin/Epigenetic
	Aurora inhibitor 1 is a potent Aurora inhibitor (IC50: ≤ 4 nM and ≤13 nM for Aurora A and Aurora B kinase).
T62789	Aurora kinase inhibitor-9	Others	Others
	Aurora kinase inhibitor-9 (compound 9d) 是一种有效的 AURKA/B 双极光激酶抑制剂，作用于 Aurora A (IC50: 0.093 μM)、Aurora B (IC50: 0.09 μM)。Aurora kinase inhibitor-9 具有广谱抗增殖活性。
T24753	SA-16 SA 16	Others	Others
	SA-16 is a potent dual inhibitor of PDK1 and Aurora kinase.
T62647	Aurora A inhibitor 2	Others	Others
	Aurora A inhibitor 2 (Compound 16h) 是一个 Aurora A kinase 的有效抑制剂 (IC50: 21.94 nM)。Aurora A inhibitor 2 能诱导 MDA-MB-231 细胞中的 caspase 依赖性凋亡。
T60783	Aurora/LIM kinase-IN-1	Others	Others
	Aurora/LIM kinase-IN-1 (Compound F114) 是aurora 和lim 激酶的有效双重抑制剂。Aurora/LIM kinase-IN-1 可抑制胶质母细胞瘤的增殖和侵袭，可能用于胶质母细胞瘤和其他癌症相关的药物研发。Aurora 和 LIM 激酶是分别参与肿瘤细胞分裂和细胞运动的激酶。
T36801	Binucleine 2	Others	Others
	Binucleine 2 is an isoform-specific and ATP-competitive inhibitor of Drosophila Aurora B kinase (Ki = 0.36 μM), a kinase involved in cell division. It is specific for Drosophila Aurora B kinase, inhibiting it in a dose-dependent manner, with minimal inhibition of human or X. laevis Aurora B kinases at concentrations up to 100 μM. Binucleine 2 induces mitotic and cytokinesis defects in Drosophila Kc167 cells. It prevents Drosophila S2 cells from assembling a contractile ring during cell division ...
T71232	Alisertib sodium hydrate	Others	Others
	Alisertib sodium hydrate is a salt of Alisertib --- an inhibitor of Aurora A kinase with potential antineoplastic activity. Alisertib binds to and inhibits Aurora A kinase, which may result in disruption of the assembly of the mitotic spindle apparatus, disruption of chromosome segregation, and inhibition of cell proliferation.
T39718	Tinengotinib	Others	Others
	Tinengotinib, a novel compound, acts as a potent modulator of protein kinases including Aurora kinase and VEGFR kinase. With its unique properties, Tinengotinib holds promise for investigating diseases marked by abnormalities in these kinases, particularly cancer-related conditions (WO2018108079A1).
T73800	Retreversine	Others	Others
	Retreversine 是 Reversine 的无活性阴性对照。Reversine 是一种 ATP-竞争性的Aurora kinase 抑制剂。
T74174	JB170	PROTACs	PROTAC
	JB170 是一种强效且高度特异性的PROTAC 介导的AURORA-A 降解剂 (DC50=28 nM)，通过将 Alisertib 连接至Cereblon 配体 Thalidomide 而形成。JB170 优先结合 AURORA-A (EC50=193 nM) 而不是 AURORA-B (EC50=1.4µM)。JB170 介导的 S 期阻滞是由 AURORA-A 耗竭引起的。JB170 对 AURORA-A 激酶的非催化功能具有很好的抑制能力。
T68740	NVP-TAC544	Others	Others
	NVP-TAC544 is a novel focal adhesion kinase (FAK) inhibitor, potently blocking kinase activity of FAK along with Aurora A, activated Cdc42-associated kinase 1 (ACK1), Met, insulin receptor (IR), TrkA, and IGF-1R.
T36932	CD532 hydrochloride	Others	Others
	CD532 hydrochloride is a potent inhibitor of Aurora A kinase, having an IC50 of 45 nM. It not only blocks the activity of Aurora A kinase but also facilitates the degradation of the protein MYCN. Furthermore, CD532 hydrochloride interacts directly with AURKA, inducing a significant conformational change. Its utility in cancer research has been demonstrated [1][2].
T72522	Aurora kinase-IN-1	Others	Others
	Aurora kinase-IN-1 是aurora kinase 的有效抑制剂。Aurora kinase-IN-1 上调 G1 细胞周期抑制蛋白 (包括 p21 和 p27) 以及 G1 进行性细胞周期蛋白 D1 的表达，并下调 G1-to-S 进行性细胞周期蛋白，导致细胞周期停滞在 G1/S 边界。Aurora 激酶-IN-1 还诱导细胞凋亡 (apoptosis）。Aurora 激酶-IN-1 是化疗药物的先导化合物。
T61527	GSK2646264	Others	Others
	GSK2646264 (Compound 44) is a highly effective and specific inhibitor of spleen tyrosine kinase (SYK) with a pIC50 of 7.1. In addition to targeting SYK, GSK2646264 also inhibits several other kinases, including LCK, LRRK2, GSK3β, JAK2, VEGFR2, Aurora B, and Aurora A, with pIC50 values of 5.4, 5.4, 5.3, 5, 4.5, <4.6 and <4.3, respectively. Notably, GSK2646264 demonstrates skin penetrability, reaching both the epidermis and dermis [1].
T68332	AKI-001	Others	Others
	AKI-001 is a potent Aurora kinase inhibitor, which exhibits low nanomolar potency against both Aurora A and Aurora B enzymes, excellent cellular potency (IC50 < 100 nM), and good oral bioavailability. Phenotypic cellular assays show that both Aurora A and Aurora B are inhibited at inhibitor concentrations sufficient to block proliferation. Importantly, the cellular activity translates to potent inhibition of tumor growth in vivo. An oral dose of 5 mg/kg QD is well tolerated and results in near s...
T38428	Alisertib sodium MLN 8237 sodium	Others	Others
	Alisertib sodium (MLN 8237) is a potent and specific inhibitor (IC50 = 1.2 nM) of Aurora A kinase, an enzyme involved in cell division. By binding to Aurora A kinase, Alisertib sodium disrupts the formation of the mitotic spindle and causes abnormal cell division. At the molecular level, it acts on the AKT/mTOR/AMPK/p38 pathway, leading to the induction of apoptosis and autophagy in leukemic cells. This compound exhibits significant antitumor activity.
T21298	SNS-314 SNS-314 free base,SNS314,SNS 314	Others	Others
	SNS-314, a synthetic small molecule Aurora kinase (AK) inhibitor with potential antineoplastic activity, selectively binds and inhibits AKs A and B, resulting in the inhibition of cell division and proliferation in tumor cells that overexpress AKs.
T71279	BPR1K653	Others	Others
	BPR1K653 is a potent Aurora kinase inhibitor with potential anticancder activity. BPR1K653 specifically inhibited the activity of Aurora-A and Aurora-B kinase at low nano-molar concentrations in vitro. BPR1K653 was potent in targeting a variety of cancer cell lines regardless of the tissue origin, p53 status, or expression of MDR1. At the cellular level, BPR1K653 induced endo-replication and subsequent apoptosis in both MDR1-negative and MDR1-positive cancer cells. Importantly, it showed potent ...
T82931	Aurora A inhibitor 3	Aurora Kinase	Cell Cycle/Checkpoint; Chromatin/Epigenetic
	Aurora A inhibitor3 (Compound 5h) 是一种抑制Aurora-A激酶活性的化合物，IC50为0.78 μM。该化合物同时对MCF-7和MDA-MB-231细胞线表现出细胞毒性，其GI50值分别为0.12 μM和0.63 μM。
T36199	AZD 1152 (hydrochloride)	Others	Others
	AZD 1152 is an orally bioavailable prodrug of AZD 1152-HQPA, a selective inhibitor of Aurora kinase B (IC50= 0.36 nM).1AZD 1152 is converted to AZD 1152-HQPA in plasma. Inhibition of Aurora B results in disruption of spindle checkpoint functions and chromosome alignment, resulting in inhibition of cytokinesis followed by apoptosis.2,3AZD 1152 inhibits tumor xenograft growthin vivo.4,5 1.Mortlock, A.A., Foote, K.M., Heron, N.M., et al.Discovery, synthesis, and in vivo activity of a new class of p...
T78753	Aurora Kinases-IN-4	Aurora Kinase	Cell Cycle/Checkpoint; Chromatin/Epigenetic
	Aurora Kinases-IN-4（Compound 11c）是共价ATP竞争型aurora kinaseA抑制剂，具有IC50为1.7 nM。该化合物对SJSA-1、MDA-MB-231、A549和HeLa细胞系的增殖抑制效果显著，其IC50分别为4.27、1.54、3.08和6.99 μM。Aurora Kinases-IN-4适用于三阴性乳腺癌（TNBC）的相关研究。
T69296	PHA-680626	Others	Others
	PHA-680626 is a potent and selective PLK inhibitor. PHA-680626 exhibits anti-proliferative and pro-apoptotic activity on Imatinib-resistant chronic myeloid leukemia cell lines and primary CD34+ cells by inhibition of both Bcr-Abl tyrosine kinase and Aurora kinases. PHA-680626 inhibits Plk1 (IC50 = 0.53 μM), Plk2 (IC50 = 0.07 μM) and Plk3 (IC50 = 1.61 μM).

化合物

Aurora kinase inhibitor-2

Cat.No: T9040

Synonym: IUN-70219,Aurora Kinase Inhibitor II

Target: Aurora Kinase

Cat.No: T6767

Synonym: Aurora A Inhibitor I

Target: Apoptosis, Aurora Kinase

Phthalazinone pyrazole

Cat.No: T21981

Target: Aurora Kinase

Cat.No: T8537

Synonym: (3E)-3-[(2,5-二羟基苯基)亚甲基]-1,3-二氢-2H-吲哚-2-酮

Target: Aurora Kinase

TC-A 2317 hydrochloride

Cat.No: T23426

Target: Others, Aurora Kinase

Aurora kinase inhibitor-3

Cat.No: T5524

Synonym: Aurora Kinase Inhibitor III

Target: Aurora Kinase

Cat.No: TQ0059

Synonym: ABT-348

Target: VEGFR, FLT, c-RET, PDGFR, Aurora Kinase

Cat.No: T6068

Synonym: VX-689,MK5108

Target: Aurora Kinase, Autophagy

Ilorasertib hydrochloride

Cat.No: T11638

Synonym: ABT-348 hydrochloride

Target: Aurora Kinase

Cat.No: T2509

Synonym: MK-0457,VX 680

Target: Aurora Kinase, Autophagy

Cat.No: T6126

Synonym: JNJ 7706621

Target: Apoptosis, CDK, Aurora Kinase

Cat.No: T2611

Synonym: CCT137690

Target: Apoptosis, Aurora Kinase

Cat.No: T50110

Target: Aurora Kinase

Cat.No: T6315

Target: Casein Kinase, PKA, Src, Aurora Kinase

Cat.No: T1825

Target: Aurora Kinase, Adenosine Receptor, Autophagy

Cat.No: T34888

Synonym: TL12 186,TL12186

Target: CDK, PROTACs

Cat.No: T2358

Target: Apoptosis, VEGFR, FGFR, FLT, c-RET, PDGFR, Src, Aurora Kinase

Cat.No: T17267

Target: IGF-1R, Bcr-Abl, Src, Aurora Kinase

SBE13 Hydrochloride

Cat.No: T2271

Synonym: SBE 13 hydrochloride,SBE 13 HCl

Target: Apoptosis, PLK, Autophagy

Cat.No: T35570

Synonym: CS2164,西奥罗尼

Target: c-Fms, VEGFR, FLT, PDGFR, c-Kit, Aurora Kinase

Cat.No: T2241

Synonym: MLN 8237,4-[[9-氯-7-(2-氟-6-甲氧基苯基)-5H-嘧啶并[5,4-D][2]苯并氮杂卓-2-基]氨基]-2-甲氧基苯甲酸

Target: Apoptosis, Aurora Kinase, Autophagy

Cat.No: T4428

Target: FLT, Aurora Kinase

KW-2450 Formate

Cat.No: T68405L

Target: Tyrosinase

(1E)-CFI-400437 dihydrochloride

Cat.No: T22288

Synonym: CFI-400437 dihydrochloride

Target: PLK

H-1152 dihydrochloride

Cat.No: T35328

Synonym: H-1152 2HCl,H-1152 dihydrochloride

Target: ROCK

Cat.No: T64338

Synonym: AKI 603,AKI-603

Target: Aurora Kinase

Aurora kinase inhibitor-8

Cat.No: T63773

Target: Others

Cat.No: T68234

Target: Others

Aurora inhibitor 1

Cat.No: T10412

Target: Aurora Kinase

Aurora kinase inhibitor-9

Cat.No: T62789

Target: Others

Cat.No: T24753

Synonym: SA 16

Target: Others

Aurora A inhibitor 2

Cat.No: T62647

Target: Others

Aurora/LIM kinase-IN-1

Cat.No: T60783

Target: Others

Cat.No: T36801

Target: Others

Alisertib sodium hydrate

Cat.No: T71232

Target: Others

Cat.No: T39718

Target: Others

Cat.No: T73800

Target: Others

Cat.No: T74174

Target: PROTACs

Cat.No: T68740

Target: Others

CD532 hydrochloride

Cat.No: T36932

Target: Others

Aurora kinase-IN-1

Cat.No: T72522

Target: Others

Cat.No: T61527

Target: Others

Cat.No: T68332

Target: Others

Alisertib sodium

Cat.No: T38428

Synonym: MLN 8237 sodium

Target: Others

Cat.No: T21298

Synonym: SNS-314 free base,SNS314,SNS 314

Target: Others

Cat.No: T71279

Target: Others

Aurora A inhibitor 3

Cat.No: T82931

Target: Aurora Kinase

AZD 1152 (hydrochloride)

Cat.No: T36199

Target: Others

Aurora Kinases-IN-4

Cat.No: T78753

Target: Aurora Kinase

Cat.No: T69296

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
TN3834	Derrone	Antifection	Microbiology/Virology
	Derrone may be interesting antimicrobial agents to be used against infectious diseases caused by many pathogens. It is also a novel Aurora kinase inhibitor, it can significantly inhibit the formation and growth of MCF7 tumor spheroids.

天然产物

Cat.No: TN3834

Target: Antifection

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-04467	NME1 Protein, Human, Recombinant (His) NME/NM23 nucleoside diphosphate kinase 1,N...	Human	E. coli
	NME1, also known as Nucleoside Diphosphate Kinase A (NDK-A), or NM23-H1, belongs to the NDK family. NM23-H1 is known to have a metastasis suppressive activity in many tumor cells. Recent studies have shown that the interacting proteins with NM23-H1 which mediate cell proliferation, may act as modulators of the metastasis suppressor activity. The interacting proteins with NM23-H1 can be classified into 3 groups. The first group of proteins can be classified as upstream kinases of NM23-H1 such as ...
TMPK-01419	Peptide Ready HLA-A03:01&B2M Monomer Protein, Human, MHC (His & Avi), Biotinylated MHC,HLA-A02:01,Peptide Ready	Human	HEK293 Cells
	Peptide Ready HLA-A03:01&B2M Monomer is absent from peptide, namely peptide-receptive MHC. It can be loaded with antigenic peptides matching HLA-A03:01. Peptide ready MHC molecules comprising human HLA alleles and B2M, which can be readily tetramerized and loaded with peptides of choice in a high-throughput manner.
TMPK-01426	Peptide Ready HLA-A11:01&B2M Monomer Protein, Human, MHC (His & Avi) HLA-A02:01,Peptide Ready,MHC	Human	HEK293 Cells
	Peptide Ready HLA-A11:01&B2M Monomer is absent from peptide, namely peptide-receptive MHC. It can be loaded with antigenic peptides matching HLA-A11:01. Peptide ready MHC molecules comprising human HLA alleles and B2M, which can be readily tetramerized and loaded with peptides of choice in a high-throughput manner.
TMPK-01421	Peptide Ready HLA-A02:01&B2M Monomer Protein, Human, MHC (His & Avi), Biotinylated HLA-A02:01,MHC,Peptide Ready	Human	HEK293 Cells
	HLA-A02:01&B2M&Peptide ready Monomer is absent from peptide, namely peptide-receptive MHC. It can be loaded with antigenic peptides matching HLA-A02:01. Peptide ready MHC molecules comprising human HLA alleles and B2M, which can be readily tetramerized and loaded with peptides of choice in a high-throughput manner.
TMPK-01420	Peptide Ready HLA-A03:01&B2M Monomer Protein, Human, MHC (His & Avi) Peptide Ready,MHC,HLA-A02:01	Human	HEK293 Cells
	Peptide Ready HLA-A03:01&B2M Monomer is absent from peptide, namely peptide-receptive MHC. It can be loaded with antigenic peptides matching HLA-A03:01. Peptide ready MHC molecules comprising human HLA alleles and B2M, which can be readily tetramerized and loaded with peptides of choice in a high-throughput manner.
TMPK-01410	Peptide Ready HLA-A*24:02&B2M Monomer Protein, Human, MHC (His & Avi) HLA-A,MHC,Peptide Ready	Human	HEK293 Cells
	Peptide Ready HLA-G&B2M Monomer is absent from peptide, namely peptide-receptive MHC. It can be loaded with antigenic peptides matching HLA-G. Peptide ready MHC molecules comprising human HLA alleles and B2M, which can be readily tetramerized and loaded with peptides of choice in a high-throughput manner.
TMPK-01422	Peptide Ready HLA-A02:01&B2M Monomer Protein, Human, MHC (His & Avi) Peptide Ready,MHC,HLA-A02:01	Human	HEK293 Cells
	Peptide Ready HLA-A02:01&B2M Monomer is absent from peptide, namely peptide-receptive MHC. It can be loaded with antigenic peptides matching HLA-A02:01. Peptide ready MHC molecules comprising human HLA alleles and B2M, which can be readily tetramerized and loaded with peptides of choice in a high-throughput manner.
TMPK-01425	Peptide Ready HLA-A11:01&B2M Monomer Protein, Human, MHC (His & Avi), Biotinylated MHC,HLA-A02:01,Peptide Ready	Human	HEK293 Cells
	Peptide Ready HLA-A11:01&B2M Monomer is absent from peptide, namely peptide-receptive MHC. It can be loaded with antigenic peptides matching HLA-A11:01. Peptide ready MHC molecules comprising human HLA alleles and B2M, which can be readily tetramerized and loaded with peptides of choice in a high-throughput manner.
TMPK-01415	APC-equivalent Peptide Ready HLA-A02:01&B2M Tetramer Protein, Human, MHC (His) Peptide Ready,HLA-A02:01,MHC	Human	HEK293 Cells
	Peptide Ready HLA-A02:01&B2M Tetramer is absent from peptide, namely peptide-receptive MHC. It can be loaded with antigenic peptides matching HLA-A02:01. Peptide ready MHC molecules comprising human HLA alleles and B2M, which can be readily tetramerized and loaded with peptides of choice in a high-throughput manner.
TMPK-01409	Peptide Ready HLA-A*24:02&B2M Monomer Protein, Human, MHC (His & Avi), Biotinylated Peptide Ready,MHC,HLA-A	Human	HEK293 Cells
	Peptide Ready HLA-G&B2M Monomer is absent from peptide, namely peptide-receptive MHC. It can be loaded with antigenic peptides matching HLA-G. Peptide ready MHC molecules comprising human HLA alleles and B2M, which can be readily tetramerized and loaded with peptides of choice in a high-throughput manner.
TMPK-01510	HLA-A*03:01&B2M&KRAS WT (VVVGAGGVGK) Tetramer Protein, Human, MHC (His & Avi) NS,NS3,KRAS2,RASK2,MHC,RALD,K-R	Human	HEK293 Cells
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target.
TMPK-01463	HLA-A*11:01&B2M&KRAS G12C (VVVGACGVGK) Monomer Protein, Human, MHC (His & Avi) C-K-RAS,KI-RAS,KRAS1,K-RA	Human	HEK293 Cells
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01429	HLA-A*11:01&B2M&KRAS G12D (VVVGADGVGK) Monomer Protein, Human, MHC (E. coli, His & Avi), Biotinylated MHC,K-Ras 2,NS,K-RAS4A,KRA	Human	E. coli
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01500	HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQV) Monomer Protein, Human, MHC (His & Avi) CTAG1,CT6.1,CTAG1B,LAGE2A	Human	HEK293 Cells
	NY-ESO-1 or New York esophageal squamous cell carcinoma 1 is a well-known cancer-testis antigen (CTAs) with re-expression in numerous cancer types. Its ability to elicit spontaneous humoral and cellular immune responses, together with its restricted expression pattern, have rendered it a good candidate target for cancer immunotherapy.
TMPK-01473	HLA-A*24:02&B2M&MAGE-A3 (IMPKAGLLI) Monomer Protein, Human, MHC (His & Avi), Biotinylated CT1.3,MAGE-3,MZ2-D,MZ2D,HLA-A2402...	Human	HEK293 Cells
	Melanoma antigen gene A3 (MAGE-A3) is one of the most immunogenic cancer testis antigens and is common in various types of cancers. MAGE-A3 can be considered as a predictor for poor prognosis and an option for vaccine immunotherapy in patients with PCa.
TMPK-01518	HLA-A*11:01&B2M&KRAS G12V (VVVGAVGVGK) Tetramer Protein, Human, MHC (His & Avi) MHC,NS,KRAS1,K-RAS2A,GTPa	Human	HEK293 Cells
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01527	HLA-A*03:01&B2M&KRAS G12V (VVVGAVGVGK) Monomer Protein, Human, MHC (His & Avi) NS,RALD,C-K-RAS,RASK2,K-RA	Human	HEK293 Cells
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01408	HLA-A*02:01&B2M&KRAS G12V (KLVVVGAVGV) Monomer Protein, Human, MHC (His & Avi), Biotinylated RALD,KRAS1,KRAS2,K-RAS2B...	Human	E. coli
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01433	HLA-A*11:01&B2M&KRAS G12C (VVVGACGVGK) Tetramer Protein, Human, MHC (His & Avi) GTPase Kras,NS3,K-Ras 2,K-RA<...	Human	HEK293 Cells
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01455	HLA-A*02:01&B2M&PRAME (SLLQHLIGL) Monomer Protein, Human, MHC (His & Avi) OIP4,PRAME,OIP-4,MAPE	Human	HEK293 Cells
	PRAME (PReferentially expressed Antigen in MElanoma) is a melanoma-associated antigen expressed in cutaneous and ocular melanomas and some other malignant neoplasms, while its expression in normal tissue and benign tumors is limited.
TMPK-01401	HLA-A*11:01&B2M&KRAS WT (VVVGAGGVGK) Monomer Protein, Human, MHC (E. coli, His & Avi) MHC,CFC2,K-Ras 2,RALD,K-RAS4A...	Human	E. coli
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target.
TMPK-01488	HLA-A*11:01&B2M&KRAS WT (VVVGAGGVGK) Monomer Protein, Human, MHC (His & Avi) K-RAS4A,MHC,GTPase Kras,...	Human	HEK293 Cells
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target.
TMPK-01442	HLA-A*02:01&B2M&P53 WT (HMTEVVRRC) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled HLA-A,P53,TP53,LFS1,MHC,BCC7,TRP53,FLJ9294...	Human	HEK293 Cells
	p53 is a tumor suppressor protein. Under stressful conditions, p53 tightly regulates cell growth by promoting apoptosis and DNA repair. When p53 becomes mutated, it loses its function, resulting in abnormal cell proliferation and tumor progression. Depending on the p53 mutation, it has been shown to form aggregates leading to negative gain of function of the protein. p53 mutant associated aggregation has been observed in several cancer tissues and has been shown to promote tumor growth.
TMPK-01445	HLA-A*02:01&B2M&MAGE-A1 (KVLEYVIKV) Monomer Protein, Human, MHC (His & Avi), Biotinylated CT1.1,MAGE1,MAGE-1,MAGE-A	Human	HEK293 Cells
	MAGE-A1 belongs to the chromosome X-clustered genes of cancer-testis antigen family and is normally expressed in the human germ line but is also overexpressed in various tumors.
TMPK-01493	HLA-A*01:01&B2M&MAGE-A3 (EVDPIGHLY) Tetramer Protein, Human, MHC (His & Avi) MZ2-D,Melanoma-associate...	Human	HEK293 Cells
	Melanoma antigen gene A3 (MAGE-A3) is one of the most immunogenic cancer testis antigens and is common in various types of cancers. MAGE-A3 can be considered as a predictor for poor prognosis and an option for vaccine immunotherapy in patients with PCa.
TMPK-01477	HLA-A*02:01&B2M&AFP (FMNKFIYEI) Monomer Protein, Human, MHC (His & Avi), Biotinylated HPAFP,FETA,Alpha-1-fetop...	Human	HEK293 Cells
	Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple tissue types that were negative for either expressed proteins.CAR T-cell immunotherapy targeting intracellular/secreted solid tumor antigens can elicit a potent antitumor response.
TMPK-01458	HLA-A*11:01&B2M&KRAS G12A (VVVGAAGVGK) Monomer Protein, Human, MHC (His & Avi) K-Ras 2,GTPase Kras,KRAS...	Human	HEK293 Cells
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01539	HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Monomer Protein, Human, MHC (His & Avi), Biotinylated CTAG1B,CT6.1,MY-ESO-1,LAGE2A,NY-E...	Human	HEK293 Cells
	NY-ESO-1 or New York esophageal squamous cell carcinoma 1 is a well-known cancer-testis antigen (CTAs) with re-expression in numerous cancer types. Its ability to elicit spontaneous humoral and cellular immune responses, together with its restricted expression pattern, have rendered it a good candidate target for cancer immunotherapy.
TMPK-01529	HLA-A*11:01&B2M&KRAS G12D (VVVGADGVGK) Monomer Protein, Human, MHC (His & Avi) K-RAS4A,KRAS1,MHC,K-RAS2...	Human	HEK293 Cells
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01484	HLA-A02:03&B2M&AFP (FMNKFIYEI) Monomer Protein, Human, MHC (His & Avi) HPAFP,FETA,AFP,AFPD,...*	Human	HEK293 Cells
	Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple tissue types that were negative for either expressed proteins.CAR T-cell immunotherapy targeting intracellular/secreted solid tumor antigens can elicit a potent antitumor response.
TMPK-01449	HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Monomer Protein, Human, MHC (E. coli, His & Avi) MHC,CT6.1,CTAG1,LAGE-2,MY-ESO-1,NY-ESO-1,E...	Human	E. coli
	NY-ESO-1 or New York esophageal squamous cell carcinoma 1 is a well-known cancer-testis antigen (CTAs) with re-expression in numerous cancer types. Its ability to elicit spontaneous humoral and cellular immune responses, together with its restricted expression pattern, have rendered it a good candidate target for cancer immunotherapy.
TMPK-01480	HLA-A*02:01&B2M&Survivin (LMLGEFLKL) Monomer Protein, Human, MHC (His & Avi), Biotinylated IAP4,Survivin,API4,BIRC5,MHC,MHC I,EPR-1,s...	Human	HEK293 Cells
	Survivin (also known as BIRC5) is an evolutionarily conserved eukaryotic protein that is essential for cell division and can inhibit cell death. Normally it is only expressed in actively proliferating cells, but is upregulated in most, if not all cancers; consequently, it has received significant attention as a potential oncotherapeutic target.
TMPK-01404	HLA-A*11:01&B2M&KRAS G12V (VVVGAVGVGK) Monomer Protein, Human, MHC (E. coli, His & Avi), Biotinylated NS,KRAS,KRAS1,KRAS2,MHC,RA	Human	E. coli
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01519	HLA-A*02:01&B2M&AFP (FMNKFIYEI) Tetramer Protein, Human, MHC (His & Avi) MHC,FETA,AFP,Alpha-feto,...	Human	HEK293 Cells
	Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple tissue types that were negative for either expressed proteins.CAR T-cell immunotherapy targeting intracellular/secreted solid tumor antigens can elicit a potent antitumor response.
TMPK-01470	HLA-A*02:01&B2M&MAGE-A4 or MAGE-A8 (KVLEHVVRV) Monomer Protein, Human, MHC (His & Avi) MAGE-A4 or MAGE-A8,M...	Human	HEK293 Cells
	MAGE-A4 and MAGE-A8 are type I membes of the melanoma associated antigen (MAGE) family. The MAGE family is a large, highly conserved group of proteins that share a common MAGE homology domain. Both MAGE-A4 and MAGE-A8 antigen-presenting peptides can be presented by HLA-A*02:01.
TMPK-01481	HLA-A*24:02&B2M&Survivin 2B (AYACNTSTL) Monomer Protein, Human, MHC (His & Avi), Biotinylated svn 2B,svn-2B,Survivin-2B	Human	HEK293 Cells
	Survivin-2B, a known splice variant of survivin, has been reported to promote cell death in some cancer cells, although it keeps prosurvival function in others.survivin-2B promoted autophagy and further regulated cell death by accumulating and stabilizing IKK alpha in the nucleus.
TMPK-01494	HLA-A01:01&B2M&CT83 (NTDNNLAVY) Tetramer Protein, Human, MHC (His & Avi) HLA-A,HLA-A0101,HLA...	Human	HEK293 Cells
	Cancer/testis antigens 83 (CT83), also called KK-LC-1 or CXorf61, recognized by cytotoxic T lymphocytes (CTL), has become a promising target for immunotherapy.
TMPK-01444	HLA-A*02:01&B2M&MAGE-A1 (KVLEYVIKV) Tetramer Protein, Human, MHC (His & Avi) MZ2-E,MAGE1A,MAGE-1 anti...	Human	HEK293 Cells
	MAGE-A1 belongs to the chromosome X-clustered genes of cancer-testis antigen family and is normally expressed in the human germ line but is also overexpressed in various tumors.
TMPK-01530	HLA-A*02:01&B2M&LMP2 (CLGGLLTMV) Monomer Protein, Human, MHC (His & Avi), Biotinylated MHC,LMP-2,PSMB9,LMP2,Macropain cha	Human	HEK293 Cells
	The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that selectively inhibit the major catalytic subunit, LMP2, of the immunoproteasome,LMP2-rich cancer cells compared to LMP2-deficient cancer cells are more sensitive to growth inhibition by the LMP2-specific inhibitor, implicating an important role of LMP2 in regulating cell growth of ma...
TMPK-01434	HLA-A*11:01&B2M&KRAS G12R (VVVGARGVGK) Tetramer Protein, Human, MHC (His & Avi) RASK2,CFC2,GTPase Kras,KRA	Human	HEK293 Cells
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01525	HLA-A*11:01&B2M&KRAS G12V (VVGAVGVGK) Monomer Protein, Human, MHC (His & Avi), Biotinylated CFC2,RALD,K-Ras 2,MHC,C-K-RAS,NS3...	Human	HEK293 Cells
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01520	HLA-A*02:01&B2M&AFP (PLFQVPEPV) Tetramer Protein, Human, MHC (His & Avi) Alpha-1-fetoprotein,AFP,HPA	Human	HEK293 Cells
	Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple tissue types that were negative for either expressed proteins.CAR T-cell immunotherapy targeting intracellular/secreted solid tumor antigens can elicit a potent antitumor response.
TMPK-01474	HLA-A*24:02&B2M&MAGE-A3 (IMPKAGLLI) Monomer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	Melanoma antigen gene A3 (MAGE-A3) is one of the most immunogenic cancer testis antigens and is common in various types of cancers. MAGE-A3 can be considered as a predictor for poor prognosis and an option for vaccine immunotherapy in patients with PCa.
TMPK-01513	HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQV) Monomer Protein, Human, MHC (His & Avi), Biotinylated CT6.1,LAGE2A,MHC,CTAG1B,CTA	Human	HEK293 Cells
	NY-ESO-1 or New York esophageal squamous cell carcinoma 1 is a well-known cancer-testis antigen (CTAs) with re-expression in numerous cancer types. Its ability to elicit spontaneous humoral and cellular immune responses, together with its restricted expression pattern, have rendered it a good candidate target for cancer immunotherapy.
TMPK-01403	HLA-A*11:01&B2M&KRAS G12V (VVGAVGVGK) Monomer Protein, Human, MHC (E. coli, His & Avi) K-Ras 2,KI-RAS,CFC2,KRAS1,GTP...	Human	E. coli
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01467	HLA-A*02:01&B2M&HPV 16 E6 (KLPQLCTEL) Monomer Protein, Human, MHC (His & Avi) HPV16,E6,Human papillomavirus typ...	Human	HEK293 Cells
	Human papillomavirus (HPV) 16 infection is a necessary condition for the pathogenesis and development of cervical cancer. The E6 protein is expressed by the HPV16 E6 gene and promotes malignant phenotype transformation, which is an important mechanism for the occurrence and development of cervical cancer.
TMPK-01448	HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Tetramer Protein, Human, MHC (E. coli, His & Avi) MHC,LAGE-2,NY-ESO-1,ESO1CTAG,MY-ESO-1,CT	Human	E. coli
	NY-ESO-1 or New York esophageal squamous cell carcinoma 1 is a well-known cancer-testis antigen (CTAs) with re-expression in numerous cancer types. Its ability to elicit spontaneous humoral and cellular immune responses, together with its restricted expression pattern, have rendered it a good candidate target for cancer immunotherapy.
TMPK-01446	HLA-A02:01&B2M&MAGE-A1 (KVLEYVIKV) Monomer Protein, Human, MHC (His & Avi) MAGE1,MAGE1A,MAGE-1 ...*	Human	HEK293 Cells
	MAGE-A1 belongs to the chromosome X-clustered genes of cancer-testis antigen family and is normally expressed in the human germ line but is also overexpressed in various tumors.
TMPK-01399	HLA-A*11:01&B2M&KRAS WT (VVGAGGVGK) Monomer Protein, Human, MHC (His & Avi), Biotinylated K-RAS2A,NS3,KRAS2,CFC2,K-RA	Human	E. coli
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target.
TMPK-01461	HLA-A*11:01&B2M&KRAS G12S (VVVGASGVGK) Monomer Protein, Human, MHC (His & Avi) C-K-RAS,KRAS,RASK2,K-Ras...	Human	HEK293 Cells
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
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重组蛋白

NME1 Protein, Human, Recombinant (His)

Cat.No: TMPY-04467

Species: Human

Expression System: E. coli

Peptide Ready HLA-A*03:01&B2M Monomer Protein, Human, MHC (His & Avi), Biotinylated

Cat.No: TMPK-01419

Species: Human

Expression System: HEK293 Cells

Peptide Ready HLA-A*11:01&B2M Monomer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01426

Species: Human

Expression System: HEK293 Cells

Peptide Ready HLA-A*02:01&B2M Monomer Protein, Human, MHC (His & Avi), Biotinylated

Cat.No: TMPK-01421

Species: Human

Expression System: HEK293 Cells

Peptide Ready HLA-A*03:01&B2M Monomer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01420

Species: Human

Expression System: HEK293 Cells

Peptide Ready HLA-A*24:02&B2M Monomer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01410

Species: Human

Expression System: HEK293 Cells

Peptide Ready HLA-A*02:01&B2M Monomer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01422

Species: Human

Expression System: HEK293 Cells

Peptide Ready HLA-A*11:01&B2M Monomer Protein, Human, MHC (His & Avi), Biotinylated

Cat.No: TMPK-01425

Species: Human

Expression System: HEK293 Cells

APC-equivalent Peptide Ready HLA-A*02:01&B2M Tetramer Protein, Human, MHC (His)

Cat.No: TMPK-01415

Species: Human

Expression System: HEK293 Cells

Peptide Ready HLA-A*24:02&B2M Monomer Protein, Human, MHC (His & Avi), Biotinylated

Cat.No: TMPK-01409

Species: Human

Expression System: HEK293 Cells

HLA-A*03:01&B2M&KRAS WT (VVVGAGGVGK) Tetramer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01510

Species: Human

Expression System: HEK293 Cells

HLA-A*11:01&B2M&KRAS G12C (VVVGACGVGK) Monomer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01463

Species: Human

Expression System: HEK293 Cells

HLA-A*11:01&B2M&KRAS G12D (VVVGADGVGK) Monomer Protein, Human, MHC (E. coli, His & Avi), Biotinylated

Cat.No: TMPK-01429

Species: Human

Expression System: E. coli

HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQV) Monomer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01500

Species: Human

Expression System: HEK293 Cells

HLA-A*24:02&B2M&MAGE-A3 (IMPKAGLLI) Monomer Protein, Human, MHC (His & Avi), Biotinylated

Cat.No: TMPK-01473

Species: Human

Expression System: HEK293 Cells

HLA-A*11:01&B2M&KRAS G12V (VVVGAVGVGK) Tetramer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01518

Species: Human

Expression System: HEK293 Cells

HLA-A*03:01&B2M&KRAS G12V (VVVGAVGVGK) Monomer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01527

Species: Human

Expression System: HEK293 Cells

HLA-A*02:01&B2M&KRAS G12V (KLVVVGAVGV) Monomer Protein, Human, MHC (His & Avi), Biotinylated

Cat.No: TMPK-01408

Species: Human

Expression System: E. coli

HLA-A*11:01&B2M&KRAS G12C (VVVGACGVGK) Tetramer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01433

Species: Human

Expression System: HEK293 Cells

HLA-A*02:01&B2M&PRAME (SLLQHLIGL) Monomer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01455

Species: Human

Expression System: HEK293 Cells

HLA-A*11:01&B2M&KRAS WT (VVVGAGGVGK) Monomer Protein, Human, MHC (E. coli, His & Avi)

Cat.No: TMPK-01401

Species: Human

Expression System: E. coli

HLA-A*11:01&B2M&KRAS WT (VVVGAGGVGK) Monomer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01488

Species: Human

Expression System: HEK293 Cells

HLA-A*02:01&B2M&P53 WT (HMTEVVRRC) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled

Cat.No: TMPK-01442

Species: Human

Expression System: HEK293 Cells

HLA-A*02:01&B2M&MAGE-A1 (KVLEYVIKV) Monomer Protein, Human, MHC (His & Avi), Biotinylated

Cat.No: TMPK-01445

Species: Human

Expression System: HEK293 Cells

HLA-A*01:01&B2M&MAGE-A3 (EVDPIGHLY) Tetramer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01493

Species: Human

Expression System: HEK293 Cells

HLA-A*02:01&B2M&AFP (FMNKFIYEI) Monomer Protein, Human, MHC (His & Avi), Biotinylated

Cat.No: TMPK-01477

Species: Human

Expression System: HEK293 Cells

HLA-A*11:01&B2M&KRAS G12A (VVVGAAGVGK) Monomer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01458

Species: Human

Expression System: HEK293 Cells

HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Monomer Protein, Human, MHC (His & Avi), Biotinylated

Cat.No: TMPK-01539

Species: Human

Expression System: HEK293 Cells

HLA-A*11:01&B2M&KRAS G12D (VVVGADGVGK) Monomer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01529

Species: Human

Expression System: HEK293 Cells

HLA-A*02:03&B2M&AFP (FMNKFIYEI) Monomer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01484

Species: Human

Expression System: HEK293 Cells

HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Monomer Protein, Human, MHC (E. coli, His & Avi)

Cat.No: TMPK-01449

Species: Human

Expression System: E. coli

HLA-A*02:01&B2M&Survivin (LMLGEFLKL) Monomer Protein, Human, MHC (His & Avi), Biotinylated

Cat.No: TMPK-01480

Species: Human

Expression System: HEK293 Cells

HLA-A*11:01&B2M&KRAS G12V (VVVGAVGVGK) Monomer Protein, Human, MHC (E. coli, His & Avi), Biotinylated

Cat.No: TMPK-01404

Species: Human

Expression System: E. coli

HLA-A*02:01&B2M&AFP (FMNKFIYEI) Tetramer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01519

Species: Human

Expression System: HEK293 Cells

HLA-A*02:01&B2M&MAGE-A4 or MAGE-A8 (KVLEHVVRV) Monomer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01470

Species: Human

Expression System: HEK293 Cells

HLA-A*24:02&B2M&Survivin 2B (AYACNTSTL) Monomer Protein, Human, MHC (His & Avi), Biotinylated

Cat.No: TMPK-01481

Species: Human

Expression System: HEK293 Cells

HLA-A*01:01&B2M&CT83 (NTDNNLAVY) Tetramer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01494

Species: Human

Expression System: HEK293 Cells

HLA-A*02:01&B2M&MAGE-A1 (KVLEYVIKV) Tetramer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01444

Species: Human

Expression System: HEK293 Cells

HLA-A*02:01&B2M&LMP2 (CLGGLLTMV) Monomer Protein, Human, MHC (His & Avi), Biotinylated

Cat.No: TMPK-01530

Species: Human

Expression System: HEK293 Cells

HLA-A*11:01&B2M&KRAS G12R (VVVGARGVGK) Tetramer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01434

Species: Human

Expression System: HEK293 Cells

HLA-A*11:01&B2M&KRAS G12V (VVGAVGVGK) Monomer Protein, Human, MHC (His & Avi), Biotinylated

Cat.No: TMPK-01525

Species: Human

Expression System: HEK293 Cells

HLA-A*02:01&B2M&AFP (PLFQVPEPV) Tetramer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01520

Species: Human

Expression System: HEK293 Cells

HLA-A*24:02&B2M&MAGE-A3 (IMPKAGLLI) Monomer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01474

Species: Human

Expression System: HEK293 Cells

HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQV) Monomer Protein, Human, MHC (His & Avi), Biotinylated

Cat.No: TMPK-01513

Species: Human

Expression System: HEK293 Cells

HLA-A*11:01&B2M&KRAS G12V (VVGAVGVGK) Monomer Protein, Human, MHC (E. coli, His & Avi)

Cat.No: TMPK-01403

Species: Human

Expression System: E. coli

HLA-A*02:01&B2M&HPV 16 E6 (KLPQLCTEL) Monomer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01467

Species: Human

Expression System: HEK293 Cells

HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Tetramer Protein, Human, MHC (E. coli, His & Avi)

Cat.No: TMPK-01448

Species: Human

Expression System: E. coli

HLA-A*02:01&B2M&MAGE-A1 (KVLEYVIKV) Monomer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01446

Species: Human

Expression System: HEK293 Cells

HLA-A*11:01&B2M&KRAS WT (VVGAGGVGK) Monomer Protein, Human, MHC (His & Avi), Biotinylated

Cat.No: TMPK-01399

Species: Human

Expression System: E. coli

HLA-A*11:01&B2M&KRAS G12S (VVVGASGVGK) Monomer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01461

Species: Human

Expression System: HEK293 Cells

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