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Search Results for " atrial natriuretic peptide "

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Cat. No. Product Name Target Signaling Pathways
TP1219 Atrial Natriuretic Peptide (ANP) (1-28), human, porcine Acetate

ANP (1-28), human, porcineANP(1-28)
Atrial Natriuretic Peptide (ANP) (1-28), human, porcine Acetate 是颗粒鸟苷酸环化酶的刺激剂，已被发现通过增加环鸟苷单磷酸的合成来保护分离的心肌细胞免受复氧诱导的高收缩。Atrial Natriuretic Peptide (ANP) (1-28), human, porcine Acetate 也有助于在反复运动期间刺激脂解，并在运动期间控制脂解。
T39244 Atrial Natriuretic Peptide (1-28), human, porcine, Biotin-labeled

Atrial Natriuretic Peptide (1-28), human, porcine, Biotin-labeled, is one of three mammalian natriuretic peptides (NPs) that exerts endocrine effects on fluid homeostasis and blood pressure. Atrial Natriuretic Peptide holds promise for cardiovascular diseases research.
TP1221 Atrial Natriuretic Peptide (ANP) (1-28), rat

Atrial natriuretic factor (1-28) (rat)
Atrial Natriuretic Peptide (1-28), rat is the major circulating form of ANP in rats.
TP1220L ANP(1-28) Acetate (human, porcine)

醋酸卡培立肽,Carperitide acetate (89213-87-6 Free base),Atrial Natriuretic Peptide (ANP) (1-28), human, porcine Acetate

 Endothelin Receptor GPCR/G Protein
Carperitide acetate (Atrial Natriuretic Peptide (ANP) (1-28), human, porcine Acetate) 是一种由 28 个氨基酸组成的激素，由心脏产生并分泌，以响应心脏损伤和机械拉伸。Carperitide acetate 抑制内皮素-1 (endothelin-1) 分泌。
T41065 Atrial natriuretic factor (1-28) (human, porcine)

Atrial natriuretic factor (1-28) (human, porcine),Atrial natriuretic peptide (1-28)
Atrial natriuretic factor (1-28) from both human and porcine sources is a powerful suppressor of pro-opiomelanocortin (POMC) mRNA, while it only has a modest inhibition effect on βEP-LI release.
TP1218 Atrial natriuretic factor (1-28) (rat) TFA

Atrial Natriuretic Peptide (ANP) (1-28), rat TFA
Atrial Natriuretic Peptide (ANP) (1-28),rat (TFA) is the main circulating forms of Atrial Natriuretic Peptide (ANP) in rats, which strongly inhibit the secretion of Ang II - stimulated endothelin-1.
TP1220 Carperitide

Atrial Natriuretic Peptide (ANP) (1-28), human, porcine
Carperitide, a 28-amino acid hormone known as Atrial Natriuretic Peptide (ANP) (1-28), is naturally synthesized and released by the human heart in reaction to cardiac injury and mechanical stretch. This compound effectively suppresses endothelin-1 secretion in a dose-dependent manner.
T80438 Atrial natriuretic peptide (3-28) (human)

ANP (3-28) (human)

 Endothelin Receptor GPCR/G Protein
Atrial natriuretic peptide (3-28) (human) 是由心房心肌细胞合成并分泌的肽类激素，主要在调节血压、体液平衡及电解质稳态方面发挥作用。
T82932 Auriculin B

Atrial natriuretic peptide(126-150)(rat),ANP (126-150) (Rat)
Auriculin B (ANP (126-150) (Rat)) 是源自大鼠的心房钠尿肽，具备显著的血管舒张与利尿作用。
T4200 Sacubitril hemicalcium salt

AHU-377 (hemicalcium salt),LCZ696中间体,AHU377 calcium salt

 Neprilysin Metabolism
Sacubitril hemicalcium salt (AHU377 calcium salt) 是一种有效的 NEP 抑制剂，IC50=5 nM。它是研究心力衰竭药物 LCZ696 的组分之一。
T30701 Candoxatrilat

UK69578,UK 69578,U 73967,U-73967,U73967,UK-69578

 Others Others
Candoxatrilat (U 73967, UK69578) is an active neutral endopeptidase inhibitor that reduces atrial natriuretic peptide degradation.
TP1872 Vasonatrin Peptide (VNP)

Vasonatrin Peptide VNP
Vasonatrin peptide (VNP) is a chimera of atrial natriuretic peptide (ANP) and C-type natriuretic peptide (CNP) with potent venodilating and natriuretic activity.
T81891 M65

M65为PAC1受体特异性拮抗剂，可抑制ANP释放。
T70471 Cgs 26303

Others Others
Cgs 26303 is a potent non-peptidic inhibitor of neutral endopeptidase capable of protecting atrial natriuretic peptide from enzymatic degradation.
T76386 ANP (1-30), frog

ANP (1-30), frog 是蛙源心房肽的多肽片段。具有利钠、利尿和血管松弛作用。
T71987 5-hydroxy Isatin

Others Others
5-hydroxy Isatin is an inhibitor of monoamine oxidase A and also inhibits atrial natriuretic peptide-induced activation of particulate guanylyl cyclase in rat brain and heart membranes.
T38641 AP 811

AP 811, a selective antagonist of the atrial natriuretic peptide clearance receptor (APN-CR, NPR3) with a K i value of 0.48 nM, exhibits remarkable selectivity for NPR3 over NPR1 by more than 20,000-fold. Moreover, AP 811 effectively eliminates ANP-induced pump stimulation.
TP1630 A-71915 TFA (132956-87-7 free base)

A-71915 TFA
A-71915 (TFA) is a selective inhibitor of ANP receptor (atrial natriuretic peptide-receptor), induces apoptosis and decreases insulin secretion in RINm5F pancreatic β-cells.
T82847 BNP (1-21), Pro (Human)

BNP (1-21), Pro (Human) 是一种由21个氨基酸组成的心脏激素多肽。作为B型利钠肽(BNP)的一部分，与心房利钠肽高度同源，共同构成了心脏的双利钠肽系统。BNP 主要参与心脏发生的调节，并涉及向子宫外环境过渡的生理进程。
T76037 A-71915 TFA

A-71915 (TFA) 为一种选择性心房利钠肽受体 (ANP receptor) 抑制剂，其作用能够诱导 RINm5F 胰腺 β 细胞凋亡，并减少胰岛素释放。
T61095 SCH-42354

Others Others
SCH-42354 is a potent, orally active inhibitor of neutral endopeptidase (NEP), serving as the active form of the prodrug SCH-42495. By inhibiting NEP hydrolysis, SCH-42354 enhances the activity of atrial natriuretic peptide (ANP) and prevents the hydrolysis of leu-enkephalin and ANF with IC50 values of 8.3 nM and 10.0 nM, respectively. Furthermore, SCH-42354 exhibits antihypertensive activity [1] [2].
T78007 Vasonatrin Peptide (VNP) TFA

Vasonatrin Peptide (VNP) TFA 是一种由心钠素 (ANP) 和C型利钠肽 (CNP) 嵌合而成的肽类化合物。它整合了CNP的静脉扩张功能、ANP的利尿效果，并展现出与ANP或CNP无关的特有动脉扩张特性。Vasonatrin Peptide TFA 透过cGMP-PKG信号途径发挥其对内质网应激介导的糖尿病心脏缺血再灌注损害的保护作用。
TP2221 ANP (1-11), rat

Others Others
Atrial Natriuretic Peptide (ANP) has the sequence of H-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-OH, is a 28 amino acid peptide. ANP is a powerful vasodilator, and a protein (polypeptide) hormone secreted by heart muscle cells. It is involved in the hom
T82993 AP 811 acetate

AP 811 acetate是一款选择性的ANP-CR（即NPR3）拮抗剂，其Ki值为0.48 nM。该化合物对NPR3的选择性是对NPR1的两万倍。此外，AP 811 acetate能够消除ANP诱导的泵激活现象。
T82941 Atriopeptin III (rat)

ANP 127-150 (rat)
Atriopeptin III (ANP 127-150) (rat)是包含24个氨基酸的心房肽，作用为有效的血管舒张剂及利尿剂。在输尿管梗阻大鼠模型中，Atriopeptin III (rat)能够改善肾功能并降低血压，同时适用于慢性肾功能衰竭研究。
T83766 Moexiprilat

RS 10029

 Others Others
Moexiprilat是一种血管紧张素转换酶(ACE; IC50 = 2.1 nM)的抑制剂，也是前药moexipril的一种活性代谢产物。通过侧链酯水解作用，在体内从moexipril转化而来。Moexiprilat (10 nM)能防止初生大鼠心脏成纤维细胞在雌激素或血管紧张素II刺激下的增殖。在以每天50 mg/kg剂量给药的去卵巢小鼠中，降低平均动脉血压，并增加心房钠尿肽水平，这是高血压的一个标志。

化合物

Atrial Natriuretic Peptide (ANP) (1-28), human, porcine Acetate
Cat.No: TP1219
Synonym: ANP (1-28), human, porcineANP(1-28)
Target:
Atrial Natriuretic Peptide (1-28), human, porcine, Biotin-labeled
Cat.No: T39244
Synonym:
Target:
Atrial Natriuretic Peptide (ANP) (1-28), rat
Cat.No: TP1221
Synonym: Atrial natriuretic factor (1-28) (rat)
Target:
ANP(1-28) Acetate (human, porcine)
Cat.No: TP1220L
Synonym: 醋酸卡培立肽,Carperitide acetate (89213-87-6 Free base),Atrial Natriuretic Peptide (ANP) (1-28), human, porcine Acetate
Target: Endothelin Receptor
Atrial natriuretic factor (1-28) (human, porcine)
Cat.No: T41065
Synonym: Atrial natriuretic factor (1-28) (human, porcine),Atrial natriuretic peptide (1-28)
Target:
Atrial natriuretic factor (1-28) (rat) TFA
Cat.No: TP1218
Synonym: Atrial Natriuretic Peptide (ANP) (1-28), rat TFA
Target:
Carperitide
Cat.No: TP1220
Synonym: Atrial Natriuretic Peptide (ANP) (1-28), human, porcine
Target:
Atrial natriuretic peptide (3-28) (human)
Cat.No: T80438
Synonym: ANP (3-28) (human)
Target: Endothelin Receptor
Auriculin B
Cat.No: T82932
Synonym: Atrial natriuretic peptide(126-150)(rat),ANP (126-150) (Rat)
Target:
Sacubitril hemicalcium salt
Cat.No: T4200
Synonym: AHU-377 (hemicalcium salt),LCZ696中间体,AHU377 calcium salt
Target: Neprilysin
Candoxatrilat
Cat.No: T30701
Synonym: UK69578,UK 69578,U 73967,U-73967,U73967,UK-69578
Target: Others
Vasonatrin Peptide (VNP)
Cat.No: TP1872
Synonym: Vasonatrin Peptide VNP
Target:
M65
Cat.No: T81891
Synonym:
Target:
Cgs 26303
Cat.No: T70471
Synonym:
Target: Others
ANP (1-30), frog
Cat.No: T76386
Synonym:
Target:
5-hydroxy Isatin
Cat.No: T71987
Synonym:
Target: Others
AP 811
Cat.No: T38641
Synonym:
Target:
A-71915 TFA (132956-87-7 free base)
Cat.No: TP1630
Synonym: A-71915 TFA
Target:
BNP (1-21), Pro (Human)
Cat.No: T82847
Synonym:
Target:
A-71915 TFA
Cat.No: T76037
Synonym:
Target:
SCH-42354
Cat.No: T61095
Synonym:
Target: Others
Vasonatrin Peptide (VNP) TFA
Cat.No: T78007
Synonym:
Target:
ANP (1-11), rat
Cat.No: TP2221
Synonym:
Target: Others
AP 811 acetate
Cat.No: T82993
Synonym:
Target:
Atriopeptin III (rat)
Cat.No: T82941
Synonym: ANP 127-150 (rat)
Target:
Moexiprilat
Cat.No: T83766
Synonym: RS 10029
Target: Others
Species：
Human (15)
Rat (1)
Expression System：
HEK293 Cells (8)
E. coli (6)
Baculovirus Insect Cells (1)
P. pastoris (Yeast) (1)
Tag：
C-His-Avi (6)
N-6xHis (2)
C-12xHis (1)
C-6xHis (1)
C-His (1)
C-hFc (1)
N-10xHis (1)
N-6xHis-Flag (1)
N-6xHis-SUMO (1)
N-hFc (1)
Cat. No. Product Name Species Expression System
TMPH-03250 NPR3 Protein, Rat, Recombinant (His & SUMO)

Npr3,Atrial natriuretic peptide r...

 Rat E. coli
Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP. May function as a clearance receptor for NPPA, NPPB and NPPC, regulating their local concentrations and effects. May regulate diuresis, blood pressure and skeletal development. Does not have guanylate cyclase activity. NPR3 Protein, Rat, Recombinant (His & SUMO) is expressed in E. coli expression system wi...
TMPH-00985 NPR3 Protein, Human, Recombinant (His)

Atrial natriuretic peptide recept...

 Human E. coli
Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP. May function as a clearance receptor for NPPA, NPPB and NPPC, regulating their local concentrations and effects. May regulate diuresis, blood pressure and skeletal development. Does not have guanylate cyclase activity. NPR3 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-...
TMPH-00982 NPR1 Protein, Human, Recombinant (E. coli, His)

Guanylate cyclase A,Atrial natriuretic

Human E. coli
NPR1 Protein, Human, Recombinant (E. coli, His) is expressed in E. coli.
TMPH-00983 NPR1 Protein, Human, Recombinant (His)

Guanylate cyclase A,Atrial natriuretic

Human P. pastoris (Yeast)
NPR1 Protein, Human, Recombinant (His) is expressed in Yeast.
TMPH-00984 NPR2 Protein, Human, Recombinant (His)

Atrial natriuretic peptide recept...

 Human E. coli
NPR2 Protein, Human, Recombinant (His) is expressed in E. coli.
TMPH-00986 CORIN Protein, Human, Recombinant (His)

TMPRSS10,Pro-ANP-converting enzyme,Heart-specific serine pro...

 Human E. coli
CORIN Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 16.0 kDa and the accession number is Q9Y5Q5.
TMPJ-00878 NPR3 Protein, Human, Recombinant (hFc)

ANPRC,ANPR-C,C5orf23,NPR-C,NPRC,NPR3,ANP-C

 Human HEK293 Cells
Atrial Natriuretic Peptide Receptor-3 (NPR3), also known as NPRC or ANPR-C, is one of the three natriuretic peptide receptors, is a type I transmembrane glycoprotein. The natriuretic system is key to the maintenance of vascular tone and cardiovascular homeostasis. Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP. May function as a clearance receptor for N...
TMPJ-00874 NT-proBNP Protein, Human, Recombinant (His & Flag)

γ-brain natriuretic peptide,Gamma-brain

Human E. coli
Brain-type Natriuretic Peptide (BNP) is a nonglycosylated peptide that is produced predominantly by ventricular myocytes and belongs to the natriuretic peptide family. Proteolytic cleavage of the 12 kDa BNP precursor gives rise to N-terminal Pro BNP (NT-proBNP) and mature BNP. N-terminal proB-type natriuretic peptide (NT-proBNP), a useful marker of heart failure (HF), is considered to be secreted mainly from the ventricle, increased serum NT-proBNP levels are also encountered in conditions such ...
TMPY-04327 VEGFB Protein, Human, Recombinant (hFc)

VRF,血管内皮生长因子,vascular endothelial growth factor B,VEGFL

 Human HEK293 Cells
Vascular endothelial growth factor-B (VEGF-B) is closely related to VEGF-A, an effector of blood vessel growth during development and disease and a strong candidate for angiogenic therapies. In detail, VEGFB can positively prevent the Ang II-induced rising in the size of cardiomyocyte as well as reduce Ang II-induced mRNA and protein levels of β-MHC (β-myosin heavy chain), BNP (brain natriuretic peptide), and ANP (atrial natriuretic peptide). Moreover, VEGFB can regulate the decline of the Ang I...
TMPY-02081 PDE2A Protein, Human, Recombinant (aa 215-900, His)

phosphodiesterase 2A, cGMP-stimulated,cGSPDE,PED2A4,PDE2A1,C...

 Human Baculovirus Insect Cells
cGMP-dependent 3',5'-cyclic phosphodiesterase, also known as cyclic GMP-stimulated phosphodiesterase and PDE2A, is a peripheral membrane protein that belongs to the cyclic nucleotide phosphodiesterase family and PDE2 subfamily. Phosphodiesterases (PDEs) comprise a family of enzymes that regulate the levels of cyclic nucleotides, key second messengers that mediate a diverse array of functions. Phosphodiesterases (PDEs) modulate signaling by cyclic nucleotides in diverse processes such as cardiac ...
TMPK-01491 HLA-A*02:01&B2M&HBV (FLLTRILTI) Monomer Protein, Human, MHC (His & Avi), Biotinylated

MHC,HBV,Hepatitis B virus

 Human HEK293 Cells
Hepatitis B virus (HBV), is the leading cause of liver diseases infecting an estimated 240 million persons worldwide. The HBV prevalence rates are variables between different countries, with an high level of endemicity in the south-eastern part of Europe. Seven main HBV-D subgenotypes have been described until now (D1-D7).
TMPK-01501 HLA-A*02:01&B2M&HBV (FLLTRILTI) Tetramer Protein, Human, MHC (His & Avi)

MHC,Hepatitis B virus,HBV

 Human HEK293 Cells
Hepatitis B virus (HBV), is the leading cause of liver diseases infecting an estimated 240 million persons worldwide. The HBV prevalence rates are variables between different countries, with an high level of endemicity in the south-eastern part of Europe. Seven main HBV-D subgenotypes have been described until now (D1-D7).
TMPK-01505 HLA-A*02:01&B2M&HPV16 E7 (YMLDLQPET) Monomer Protein, Human, MHC (His & Avi), Biotinylated

E7,MHC,HPV16

 Human HEK293 Cells
HPV16 E7 protein, one of the primary target proteins in molecular targeted therapy for HPV-induced cervical cancer. The affitoxin, ZHPV16E7 affitoxin384 was generated by fusing the modified Pseudomonas Exotoxin A (PE38KDEL) to the HPV16 E7-specific affibody.
TMPK-01492 HLA-A*02:01&B2M&HBV (FLLTRILTI) Monomer Protein, Human, MHC (His & Avi)

Hepatitis B virus,HBV,MHC

 Human HEK293 Cells
Hepatitis B virus (HBV), is the leading cause of liver diseases infecting an estimated 240 million persons worldwide. The HBV prevalence rates are variables between different countries, with an high level of endemicity in the south-eastern part of Europe. Seven main HBV-D subgenotypes have been described until now (D1-D7).
TMPK-01504 HLA-A*02:01&B2M&HPV16 E7 (YMLDLQPET) Tetramer Protein, Human, MHC (His & Avi)

MHC,HPV16,E7

 Human HEK293 Cells
HPV16 E7 protein, one of the primary target proteins in molecular targeted therapy for HPV-induced cervical cancer. The affitoxin, ZHPV16E7 affitoxin384 was generated by fusing the modified Pseudomonas Exotoxin A (PE38KDEL) to the HPV16 E7-specific affibody.
TMPK-01506 HLA-A*02:01&B2M&HPV16 E7 (YMLDLQPET) Monomer Protein, Human, MHC (His & Avi)

HPV16,E7,MHC

 Human HEK293 Cells
HPV16 E7 protein, one of the primary target proteins in molecular targeted therapy for HPV-induced cervical cancer. The affitoxin, ZHPV16E7 affitoxin384 was generated by fusing the modified Pseudomonas Exotoxin A (PE38KDEL) to the HPV16 E7-specific affibody.

重组蛋白

NPR3 Protein, Rat, Recombinant (His & SUMO)
Cat.No: TMPH-03250
Species: Rat
Expression System: E. coli
NPR3 Protein, Human, Recombinant (His)
Cat.No: TMPH-00985
Species: Human
Expression System: E. coli
NPR1 Protein, Human, Recombinant (E. coli, His)
Cat.No: TMPH-00982
Species: Human
Expression System: E. coli
NPR1 Protein, Human, Recombinant (His)
Cat.No: TMPH-00983
Species: Human
Expression System: P. pastoris (Yeast)
NPR2 Protein, Human, Recombinant (His)
Cat.No: TMPH-00984
Species: Human
Expression System: E. coli
CORIN Protein, Human, Recombinant (His)
Cat.No: TMPH-00986
Species: Human
Expression System: E. coli
NPR3 Protein, Human, Recombinant (hFc)
Cat.No: TMPJ-00878
Species: Human
Expression System: HEK293 Cells
NT-proBNP Protein, Human, Recombinant (His & Flag)
Cat.No: TMPJ-00874
Species: Human
Expression System: E. coli
VEGFB Protein, Human, Recombinant (hFc)
Cat.No: TMPY-04327
Species: Human
Expression System: HEK293 Cells
PDE2A Protein, Human, Recombinant (aa 215-900, His)
Cat.No: TMPY-02081
Species: Human
Expression System: Baculovirus Insect Cells
HLA-A*02:01&B2M&HBV (FLLTRILTI) Monomer Protein, Human, MHC (His & Avi), Biotinylated
Cat.No: TMPK-01491
Species: Human
Expression System: HEK293 Cells
HLA-A*02:01&B2M&HBV (FLLTRILTI) Tetramer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01501
Species: Human
Expression System: HEK293 Cells
HLA-A*02:01&B2M&HPV16 E7 (YMLDLQPET) Monomer Protein, Human, MHC (His & Avi), Biotinylated
Cat.No: TMPK-01505
Species: Human
Expression System: HEK293 Cells
HLA-A*02:01&B2M&HBV (FLLTRILTI) Monomer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01492
Species: Human
Expression System: HEK293 Cells
HLA-A*02:01&B2M&HPV16 E7 (YMLDLQPET) Tetramer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01504
Species: Human
Expression System: HEK293 Cells
HLA-A*02:01&B2M&HPV16 E7 (YMLDLQPET) Monomer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01506
Species: Human
Expression System: HEK293 Cells
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