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Search Results for " ascr "

Targets Recommended: ALK TGF-beta/Smad

1

抑制剂 & 化合物

6

天然产物

1

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T76858	Ascrinvacumab PF-03446962	ALK; TGF-beta/Smad	Angiogenesis; Stem Cells; Tyrosine Kinase/Adaptors
	Ascrinvacumab (PF-03446962) 是一种针对 ALK-1 的高效人源化 IgG2 单克隆抗体。Ascrinvacumab 对人 ALK1 的 Kd 值为 7 nM。Ascrinvacumab 对 TGF-β 有抑制作用，可用于研究肝细胞癌 (HCC)。

化合物

Ascrinvacumab

Cat.No: T76858

Synonym: PF-03446962

Target: ALK, TGF-beta/Smad

Cat. No.	Product Name	Target	Signaling Pathways
T13557	Ascr#5 Ascaroside C3	Others	Others
	Ascr#5 (asc-ωC3)是秀丽隐杆线虫中高度保守的蛔苷类物质，可调节秀丽隐杆线虫的多种反应。
T13555	Ascr#2 Ascaroside C6	Others	Others
	Ascr#2 (asc-C6-MK)是秀丽隐杆线虫中的糖苷类化合物，促进 dauer 形成。Ascr#2 在低浓度下与 ascr#3 的混合物可作为雄性引诱剂，可用于检测种群密度。
T38515	Ascr#7	Others	Others
	Ascr#7, an ascaroside-based hormonal compound, plays a significant role in nematode physiology. It is specifically expressed throughout the various stages of nematode development. Notably, ascarosides exhibit the capability to initiate the formation of dauer larvae, which are characterized by their long lifespan and exceptional stress resistance.
T38304	Ascr#18	Others	Others
	Ascr#18 is an ascaroside hormone that is expressed throughout nematode development. It exhibits the ability to enhance resistance against a range of infections, including viral, bacterial, oomycete, fungal, and nematode, in Arabidopsis, tomato, potato, and barley[1].
T13558	Ascr#8	Others	Others
	Ascr#8 is a dauer-inducing ascaroside isolated from Caenorhabditis elegans. It synergizes with ascr#2 and ascr#3, and strongly enhances male attraction.
T13556	Ascr#3	Others	Others
	Ascr#3, an ascaroside isolated from Caenorhabditis elegans, acts as a potent male attractant, and also promotes dauer formation combined with ascr#2 at low concentration.

天然产物

Cat.No: T13557

Synonym: Ascaroside C3

Target: Others

Cat.No: T13555

Synonym: Ascaroside C6

Target: Others

Cat.No: T38515

Target: Others

Cat.No: T38304

Target: Others

Cat.No: T13558

Target: Others

Cat.No: T13556

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-03842	PRNP/Prion Protein Protein, Human, Recombinant (hFc) PrPc,GSS,p27-30,ASCR,AltPrP,PRIP,PrP33-35C,PrP,CD23...	Human	HEK293 Cells
	Prion protein (PRNP) gene is well known for affecting mammal transmissible spongiform encephalopathies (TSE), and is also reported to regulate phenotypic traits (e.g. growth traits) in healthy ruminants. PRNP is fundamental in the pathogenesis of transmissible spongiform encephalopathies. Generally, PRNP gene is associated with prion diseases, whereas variants of the PRNP gene may also explain some cases of Alzheimer disease (AD) and frontotemporal dementia (FTD) in Caucasian populations.

重组蛋白

PRNP/Prion Protein Protein, Human, Recombinant (hFc)

Cat.No: TMPY-03842

Species: Human

Expression System: HEK293 Cells

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