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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T0940 |
Acesulfame Potassium
|
Others | Others |
Acesulfame potassium 是一种人造甜味剂,长期使用会影响认知功能,可能改变小鼠的神经代谢功能。 | |||
T33639 |
Neotame
NC 00723,HSDB 7965,NC-00723,NC00723,纽甜 |
Others | Others |
Neotame (HSDB 7965) 是阿斯巴甜的衍生物,是低热量、高效的人造甜味剂,非营养性甜味剂和增味剂,其甜度是糖的 7000-13,000 倍,可用于多种食品。 | |||
T0889 |
Saccharin
O-Sulfobenzimide,O-Benzoic sulfimide,Saccharimide,Benzoic sulfimide,糖精 |
Others; Antibacterial | Microbiology/Virology; Others |
Saccharin (O-Sulfobenzimide) 是一种口服有效的人造甜味剂,具有抑菌和微生物调节特性。 | |||
T0941 |
Cyclamic acid
Cyclamate,NSC 220327,Cyclohexylsulfamic acid,环己基氨基磺酸,环拉酸 |
Others | Others |
Cyclamic acid (NSC-220327) 是食品和药品中应用最广泛的一种人造甜味剂。 | |||
T19139 |
4-Nitrophenyl α-D-galactopyranoside
PNP-alpha-D-Gal,4-硝基苯-α-D-吡喃半乳糖苷,PNP-α-D-Gal |
Others | Others |
4-Nitrophenyl α-D-galactopyranoside (PNP-alpha-D-Gal) 是 4-硝基苯基 (pNP) 糖吡喃糖苷的人工底物,可用于 α-半乳糖苷酶活性的检测。它用作底物能够显著增加 pNP 的释放量。 | |||
T7593 |
Levomefolate calcium
左旋甲状腺素钙,L-5-甲基四氢叶酸钙 |
Antifolate | Cell Cycle/Checkpoint |
Levomefolate calcium 是一种人工形式的叶酸。它是叶酸的一种辅酶形式,是膳食补充剂中生物利用度更高的替代品。 | |||
T0697 |
Aspartame
阿斯巴甜,SC-18862 |
Others; Taste receptor | Metabolism; Others |
Aspartame (SC-18862) 是一种二肽的甲酯,由苯丙氨酸 (50%),天门冬氨酸 (40%) 和甲醇 (10%) 组成。它可用作合成的非营养性甜味剂。 | |||
T18923 |
BCIP
5-溴-4-氯-3-吲哚基磷酸酯对甲苯胺盐,BCIP p-toluidine salt,X-phosphate p-toluidine salt |
Others | Others |
BCIP (BCIP p-toluidine salt) 是一种显色底物,可用于碱性磷酸酶活性的比色法检测。 | |||
TN2258 |
Tartrazine
酒石黄,FD&C Yellow No. 5,Acid Yellow 23,酸性黄 23 |
Others | Others |
Tartrazine (Acid Yellow 23) 是偶氮型酸性染料,是橙黄色粉末,溶于水中呈黄色,常用作食品着色的合成柠檬黄色偶氮染料。 | |||
T64561 |
DPhPC
|
Others | Others |
DPhPC 是一种用于合成脂质体,常用于人工膜基质。DPhPC 双层膜在没有孔/离子通道的情况下不允许离子泄漏。DPhPC可用于研究通道蛋白质和膜结构。 | |||
T38808 |
Cyclamic acid sodium
Cyclohexylsulfamicacidsodium,Sodiumcyclamate |
Carbonic Anhydrase | Metabolism |
Cyclamic acid sodium (Cyclohexylsulfamicacidsodium) 是一种碳酸酐酶抑制剂,是食品和药品中使用最广泛的人工甜味剂之一。Cyclamic acid sodium 在最大电休克惊厥发作模型显示出中等的抗惊厥活性。Cyclamic acid sodium 可用于研究癌症。 | |||
T35037 |
Vanilmandelic acid, L-(+)-
Vanilmandelic acid L-form,(+)-Vanilmandelic acid |
Others | Others |
Vanilmandelic acid, L-(+)- is a chemical intermediate in the synthesis of artificial vanilla flavorings and is an end-stage metabolite of the catecholamines, epinephrine, and norepinephrine. It is produced via intermediary metabolites. | |||
T31707 |
Ethyl aspartylphenylalaninate
|
Others | Others |
Ethyl aspartylphenylalaninate is an artificial non-saccharide sweetener used as a sugar substitute. | |||
T30172 |
Aspartame acesulfame
乙酰舒泛-阿司帕坦盐,Aspartame acesulfame salt,Acesulfame mixture with aspartame |
Others | Others |
Aspartame acesulfame, as an artificial sweetener, is 350 times sweeter than sucrose. | |||
T84377 |
1,2-Dilinoleoyl-sn-glycero-3-PC
Dilinoleoyllecithin |
Others | Others |
1,2-Dilinoleoyl-sn-glycero-3-PC(Dilinoleoyllecithin)为一种磷脂,主要应用于人造膜的制造。 | |||
T70274 |
FR171456
|
Others | Others |
FR171456 is a natural specific inhibitor of mammalian nsdhl and yeast erg26p, inhibiting an artificial hepatitis c viral replicon, and showung broad antifungal activity | |||
T19977 |
Saccharin sodium
CCRIS 706,Saccharin, sodium |
Others | Others |
Saccharin sodium is a type of artificial or nonnutritive sweetener. Saccharin sodium is used in the production of various foods and pharmaceutical products. | |||
T85306 |
1-Stearoyl-2-hydroxy-sn-glycero-3-PG sodium
1-Stearoyl-2-hydroxy-sn-glycero-3-phosphoglycerol,18:0 Lyso-PG,1-Stearoyl-2-hydroxy-sn-glycero-3-phospho-(1'-rac-glycerol) |
Others | Others |
1-Stearoyl-2-hydroxy-sn-glycero-3-PG, a lysophospholipid characterized by the presence of stearic acid (18:0) at the sn-1 position, finds application in the creation of micelles, liposomes, and various artificial membranes, including those utilized in lipid-based drug delivery systems. | |||
T83161 |
Advantame
|
Others | Others |
Advantame为阿斯巴甜衍生物,属于无热量合成甜味剂,广泛应用于食品添加剂领域。 | |||
T85302 |
1-Oleoyl-2-hydroxy-sn-glycero-3-PG sodium
1-Oleoyl-2-hydroxy-sn-glycero-3-phospho-(1'-rac-glycerol),1-Oleoyl-2-hydroxy-sn-glycero-3-phosphoglycerol,18:1 Lyso-PG |
Others | Others |
1-Oleoyl-2-hydroxy-sn-glycero-3-PG (sodium salt), a lysophospholipid with oleic acid (18:1) at the sn-1 position, finds application in creating micelles, liposomes, and various artificial membranes, notably in lipid-based drug delivery systems. | |||
T84376 |
1-Palmitoyl-2-Oleoyl-sn-glycero-3-PA
1-Palmitoyl-2-Oleoyl-sn-glycero-3-Phosphatidic Acid,16:0-18:1 PA,1-Hexadecanoyl-2-Octadecanoyl-sn-glycero-3-phosphatidic Acid,1-Hexadecanoyl-2-Octadecenoyl-sn-glycero-3-phosphate,1-Palmitoyl-2-Oleoyl-sn-glycero-3-phosphate,16:0/18:1-PA,1-Hexadecanoyl-2-Octadecenoyl-sn-glycero-3-PA,PA(16:0/18:1),1,2-POPA |
Others | Others |
1-Palmitoyl-2-oleoyl-sn-glycero-3-PA (1,2-POPA) is a phospholipid featuring a palmitic acid (16:0) chain that is saturated and an oleic acid (18:1) chain that is monounsaturated, positioned at the sn-1 and sn-2 locations, respectively. This compound is utilized in creating micelles, liposomes, and various artificial membrane forms. | |||
T84374 |
1,2-Dibehenoyl-sn-glycero-3-phosphocholine
DBPC |
Others | Others |
1,2-Dibehenoyl-sn-glycero-3-phosphocholine (DBPC) 是细胞膜中的一种磷脂, 可用于胶束、脂质体和其他人工膜的制备。 | |||
T76312 |
sGnRH-A
|
||
sGnRH-A,一种鲑鱼促性腺激素释放激素(GnRH)类似物,能够促进生长激素的分泌,并作为人工授精中的排卵诱导剂使用。 | |||
T62671 |
FAAH/MAGL-IN-3
|
Others | Others |
FAAH/MAGL-IN-3 (Compound 10) 是一种不可逆的脂肪酸酰胺水解酶 (FAAH)和单酰基甘油脂酶 (MAGL)双重抑制剂,能够作用于 FAAH (IC50: 179 nM) 和 MAGL (IC50: 759 nM)。FAAH/MAGL-IN-3 表现出很小的 PAMPA (平行人工膜渗透性试验) 透过性。 | |||
T84375 |
1-Palmitoyl-2-Linoleoyl-sn-glycero-3-PC
16:0-18:2 PC,1-Palmitoyl-2-Linoleoyl-sn-glycero-3-Phosphatidylcholine,PLPC |
Others | Others |
1-Palmitoyl-2-Linoleoyl-sn-glycero-3-phosphatidylcholine (PC) is a phospholipid characterized by the incorporation of palmitic (16:0) and linoleic (18:2) acids at the sn-1 and sn-2 positions, respectively. It is utilized in the creation of micelles, liposomes, and various artificial membranes, playing a significant role in research on lipid peroxidation. | |||
T37313 |
ITH15004
|
Others | Others |
ITH15004 is a non-nucleotide antagonist of the purinergic P2X7receptor (IC50= 9 μM in HEK293 cells expressing the human receptor).1It inhibits ATP-induced currents inX. laevisoocytes expressing the human P2X7receptor when used at a concentration of 100 μM. ITH15004 (1 μM) decreases IL-1β release from LPS-primed, ATP-stimulated isolated mouse peritoneal macrophages. It has high permeability in a parallel artificial membrane permeability assay (PAMPA). 1.Calzaferri, F., Narros-Fernández, P., de Pa... | |||
T76312L |
sGnRH-A acetate
|
||
sGnRH-A醋酸盐是一种鲑鱼促性腺激素释放激素(GnRH)类似物。它能促进生长激素的分泌,并用作人工授精时的排卵诱导剂。 | |||
T64219 |
PI3K/mTOR Inhibitor-6
|
Others | Others |
PI3K/mTOR Inhibitor-6 (Compound 19c) 是一种有效的 PI3K/mTOR 双重抑制剂,在人工胃液中的稳定性比 gedatolisib 更高。10 μM 的 PI3K/mTOR Inhibitor-6 能够明显抑制 PI3K/Akt/mTOR 信号通路。PI3K/mTOR Inhibitor-6 对癌症疾病表现出研究潜力。 | |||
T62558 |
FAAH-IN-5
|
Others | Others |
FAAH-IN-5 (Compound 7) 是一种相对选择性的、不可逆的脂肪酸酰胺水解酶 (FAAH) 抑制剂 (IC50: 10.5 nM)。FAAH-IN-5 具有低 PAMPA (平行人工膜渗透性试验) 透过性。 | |||
T36034 |
CAY10774
|
Others | Others |
CAY10774 is an inhibitor of the protein-protein interaction between programmed cell death 1 (PD-1) and its ligand PD-L1 (IC50= 15 nM in a homologous time-resolved fret (HTRF) assay).1It increases the activation of Jurkat cells expressing PD-1 in co-culture with artificial antigen-presenting cells (aAPCs) expressing PD-L1 (EC50= 6.6 μM in a reporter assay). CAY10774 increases surface expression of PD-1 on primary human CD4+and CD8+T cells co-cultured with aAPCs. 1.Konieczny, M., Musielak, B., Koc... | |||
T37865 |
9(S)-HOTrE
|
Others | Others |
9(S)-HOTrE is a monohydroxy polyunsaturated fatty acid produced by the action of 5-lipoxygenase on α-linolenic acid. 9(S)-HOTrE is predominantly localized in cellular ester lipids of Glechoma hederacea leaves and is partially released during artificial dehydration. The biological role of 9(S)-HOTrE in G. hederacea leaves is still undetermined, but it may play a role in natural senescence. 9(S)-HOTrE is an inhibitor of spore germination and germ tube elongation of rice blast fungus with ED50 valu... | |||
T73707 |
Insulin Detemir
|
||
InsulinDetemir 是一种人工胰岛素,具有控制血糖水平的作用。InsulinDetemir 通过激活 Akt 和细胞外信号调节激酶 (ERK) 依赖的-cat 和 CREB 信号通路,促进 Gcg 表达,从而刺激 GLP-1的分泌。地特胰岛素可用于 2 型糖尿病的研究。 | |||
T84406 |
5α-Androst-16-en-3-one
Androstenone |
Others | Others |
5α-Androst-16-en-3-one, a mammalian pheromone present in boar saliva, plays a crucial role in facilitating social and sexual interactions by acting as a volatile chemical cue. It is utilized to prime sows in estrus for mating or artificial insemination, underscoring its significance in reproductive behavior. Additionally, this compound is detected in human sweat and urine, where it is involved in studies concerning receptor-mediated odorant detection and the genetic foundations of anosmias, ther... | |||
T31194 |
Dalapon
Basfapon B,Dowpon M,Dawpon-Rae |
Others | Others |
Dalapon is a selective herbicide used to control perennial grasses. The major use of dalapon is on food crops including sugarcane and sugar beets. Its use is no longer authorized in France. The National Institute for Occupational Safety and Health in the |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T7926 |
Carmoisine
Azo Rubine,Chromotrope FB,偶氮玉红,铬变素FB |
Others | Others |
Carmoisine (Azo Rubine) 是一种可用作食品添加剂的偶氮染料。 | |||
T2767 |
Neohesperidin Dihydrochalcone
NHDC,新橙皮苷二氢查尔酮,新橙皮苷二氢查耳酮,Neohesperidin DC,NCI-c60764 |
Reactive Oxygen Species | Immunology/Inflammation; Metabolism; NF-κB |
Neohesperidin Dihydrochalcone (Neohesperidin DC) 是一种合成的糖苷查耳酮,可用作低热量人造甜味剂,添加到各种食品和饮料中。 | |||
T2761 |
Naringin dihydrochalcone
Naringin DC,柚皮苷二氢查尔酮,柚皮甙二氢查尔酮 |
P450; NF-κB | Metabolism; NF-κB |
Naringin dihydrochalcone (Naringin DC) 是一种新型甜味剂,是来自柚皮苷的一种人工甜味剂。它也是一种CYP enzymes 的抑制剂。 | |||
T1399 |
Sucralose
Trichlorosucrose,三氯蔗糖,E955 |
Others; Endogenous Metabolite | Metabolism; Others |
Sucralose 是一种无营养的人工甜味剂 (sweetener) 和代糖,它能够激活保守神经的禁食响应,从而刺激啮齿动物产生食欲。 | |||
TN1467 |
Carmine
|
Others | Others |
Carmine is used in the manufacture of artificial flowers, paints, crimson ink, rouge, and other cosmetics, and is routinely added to food products such as yogurt, candy and certain brands of juice, the most notable ones being those of the ruby-red variety | |||
TN2982 |
3-Phenyl-2-propen-1-ol
|
Others | Others |
The compounds 3-phenyl-2-propen-1-ol , 2-methyl-3-butyn-2-ol, 3,7-dimethylnonane, and 2-hydroxybenzoic acid occurred only during estrus which may be considered as marker for detection of estrus which would ultimately help for artificial insemination in captive condition. | |||
TN5580 |
Rediocide A
|
||
Rediocide A, an insecticide, can inhibit calcium mobilization in Drosophila G-protein- coupled receptors (GPCR)s other than methuselah, it can induce GPCR desensitization and internalization, and such effects are mediated by the activation of conventional | |||
T36439 |
Gramicidin A
|
Antibacterial; HIF; Parasite | Angiogenesis; Chromatin/Epigenetic; Microbiology/Virology |
Gramicidin A 是一种从从 B. brevis 分离出来的多肽类抗生素。Gramicidin A 是一种高度疏水的通道形成离子载体,在人工膜中形成一价阳离子可渗透的通道。Gramicidin A 诱导缺氧诱导因子 1α (HIF-1α) 的降解,并能降低人肾细胞癌小鼠异种移植模型的生长。Gramicidin A 具有抗菌、抗疟活性以及溶血活性。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-01397 |
LANCL1 Protein, Human, Recombinant (His & Myc)
LANCL1,40 kDa erythrocyte membrane protein,Glutathione S-tra... |
Human | E. coli |
Functions as glutathione transferase. Catalyzes conjugation of the glutathione (GSH) to artificial substrates 1-chloro-2,4-dinitrobenzene (CDNB) and p-nitrophenyl acetate. Mitigates neuronal oxidative stress during normal postnatal development and in response to oxidative stresses probably through GSH antioxidant defense mechanism. May play a role in EPS8 signaling. Binds glutathione. LANCL1 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc... | |||
TMPY-04771 |
CARKL Protein, Human, Recombinant (His & GST)
SHK,CARKL,sedoheptulokinase |
Human | Baculovirus Insect Cells |
CARKL, also known as SHPK, is a nonprotein kinase of glucose metabolism. CARKL has weak homology to several carbohydrate kinases, a class of proteins involved in the phosphorylation of sugars as they enter a cell, inhibiting return across the cell membrane. CARKL catalyzes an orphan reaction in the pentose phosphate pathway, refocusing cellular metabolism to a high-redox state upon physiological or artificial downregulation. CARKL-dependent metabolic reprogramming is required for proper M1- and ... |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TMIH-0523 |
Sodium cyclamate-d4
|
||
Sodium cyclamate-d4 是 Sodium cyclamate 的氘代化合物。Sodium cyclamate 的 CAS 号为 139-05-9。Cyclamic acid sodium是一种碳酸酐酶抑制剂,是食品和药品中使用最广泛的人工甜味剂之一。Cyclamic acid sodium在最大电休克惊厥发作模型显示出中等的抗惊厥活性。Cyclamic acid sodium可用于研究癌症。 |