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Cat. No. | Product Name | ||
---|---|---|---|
L3510 | 甲基化化合物库 | 128 compounds | |
128 种甲基化相关的化合物,可以用于高通量和高内涵筛选; |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T35449 |
α-(difluoromethyl)-DL-Arginine
DFMA,RMI 71897,α-(difluoromethyl)-DL-Arginine |
Others | Others |
α-(difluoromethyl)-DL-Arginine (RMI 71897) 是一种酶激活的、不可逆的大肠杆菌(Ki = 800 μM)、铜绿假单胞菌和肺炎克雷伯菌精氨酸脱羧酶抑制剂。在0.01 mM 时,它已被证明可以防止渗透胁迫诱导的燕麦叶片细胞精氨酸脱羧酶活性和腐胺合成的增加。当α-(difluoromethyl)-DL-Arginine 与多种多胺类似物联用时,能在10 mM 的最低浓度下抑制克氏锥虫在哺乳动物宿主细胞中的生长,并在T 细胞受体α缺陷小鼠模型中阻止小锥虫的生长。 | |||
T7495 |
Hexa-D-arginine
|
Others | Others |
Hexa-D-arginine 是稳定的furin 抑制剂,能够作用于 furin (Ki:106 nM)、PACE4 (Ki:580 nM)、PC1 (Ki:13.2 nM)。它在体外和体内均可阻断假单胞菌外毒素 A 和炭疽毒素的毒性。 | |||
T9537 |
N'-Nitro-D-arginine
N'-Nitro-D-arginine,H-D-Arg(NO2)-OH,(R)-2-Amino-5-(3-nitroguanidino)pentanoic acid,N'-硝基-D-精氨酸 |
Others | Others |
N'-Nitro-D-arginine (N'-Nitro-D-arginine) 是一种砌块。 | |||
T9096 |
Nω-Hydroxy-nor-L-Arginine Dihydrochloride
|
Arginase | Immunology/Inflammation |
Nω-Hydroxy-nor-L-Arginine Dihydrochloride 是一种竞争性和可逆的精氨酸酶抑制剂。 | |||
T21546 |
NG,NG-dimethyl-L-Arginine dihydrochloride
|
NO Synthase | Immunology/Inflammation |
NG,NG-dimethyl-L-Arginine dihydrochloride 是一种内源性一氧化氮合酶抑制剂。由 L-精氨酸合成的一氧化氮 (NO) 有助于调节血压和宿主防御。 | |||
T31726 |
Etrasimod arginine
APD334 L-Arginine |
Others | Others |
Etrasimod arginine is used in the Treatment of Autoimmune and Inflammatory Diseases. | |||
T38786 |
Nω-Propyl-L-arginine
N-omega-Propyl-L-arginine,Nω-Propyl-L-arginine |
Others | Others |
Nω-Propyl-L-arginine, a powerful and specific inhibitor of neuronal nitric oxide synthase (nNOS), effectively inhibits nNOS with a Ki of 57 nM. It exhibits a remarkable 149-fold selectivity for nNOS over endothelial NOS (eNOS). | |||
T30032 |
Amoxycillin arginine salt
Amoxycillin L-arginine salt |
Others | Others |
Amoxycillin arginine salt is a bioactive chemical. | |||
T31878 |
Fructose-arginine
Arginyl fructose,Fructose arginine,Arginyl-fructose,J1.147.777A |
Others | Others |
Fructose-arginine is a maillard reaction product. | |||
T69001 |
Perindopril arginine
|
Others | Others |
Perindopril arginine is an angiotensin converting enzyme inhibitor, and amlodipine, a dihydropyridine calcium channel blocker, and is indicated for the treatment of hypertension, to lower blood pressure. | |||
T9857 |
Vasopressin
antidiuretic hormone (ADH),argipressin,arginine vasopressin (AVP) |
Endogenous Metabolite | Metabolism |
Vasopressin (argipressin) 是一种由下丘脑神经元合成的环状九肽,是肽原激素合成中的一种激素。Vasopressin 参与下丘脑-垂体-肾上腺轴调节过程,增加无溶质水从肾小管的滤液中重新吸收回循环中的量,收缩小动脉提高压强,增强促肾上腺皮质激素释放因子的刺激作用调节垂体促肾上腺皮质激素分泌。Vasopressin 在神经传导过程中可作为神经递质,与特定的 G 蛋白偶联受体结合发挥作用。 | |||
T39766 |
Nor-NOHA monoacetate
Nor NOHA monoacetate,Nω-Hydroxy-nor-L-arginine monoacetate |
Arginase | Immunology/Inflammation |
nor-NOHA monoacetate (Nω-Hydroxy-nor-L-arginine) 是一种具有高效性和选择性的精氨酸酶抑制剂。nor-NOHA monoacetate 抑制大鼠肝精氨酸酶,抑制L-精氨酸水解,可用于研究心血管和阻塞性气道疾病。 | |||
T41330 |
D-Arginine
|
||
D-Arginine 在生命科学相关研究中具有广泛的应用。 | |||
TP1167 |
Fmoc-Arg-OH
FMOC-L-精氨酸,Fmoc-L-Arginine |
Others | Others |
Fmoc-Arg-OH (Fmoc-L-Arginine) 是 Fmoc 修饰的精氨酸,可用于合成多肽。 | |||
T9376 |
Nitroarginine
N'-硝基-L-精氨酸,N'-Nitro-L-arginine |
NO Synthase | Immunology/Inflammation |
Nitroarginine (N'-Nitro-L-arginine) 是一氧化氮合酶的竞争性抑制剂,可选择性减少流向肿瘤细胞的血流。 | |||
T20490 |
Z-Arg(Z)2-OH
NSC120011,NSC-120011,NSC 120011,Tris(benzyloxycarbonyl)arginine |
Others | Others |
Z-Arg(Z)2-OH 可用于检测螨匀浆中的蛋白水解活性的实验中。 | |||
T35886 |
L-hydroxy Arginine (acetate)
|
||
L-hydroxy Arginine is a substrate for nitric oxide synthase in the catabolism of L-arginine to form nitric oxide. It has been used as a biomarker for reduced nitric oxide formation in patients with cardiovascular disease and metabolic syndrome. | |||
T38819 |
Nω-allyl-L-arginine
|
Others | Others |
Nω-allyl-L-arginine is a competitive and reversible inhibitor of bovine brain nitric oxide synthase (nNOS), efficiently inactivating nNOS in a time-dependent manner. Additionally, Nω-allyl-L-arginine acts as a substrate, generating L-arginine, acrolein, and H2O. | |||
T30126 |
Arginine caprate
|
Others | Others |
Arginine caprate is a biochemical. | |||
T38017 |
Nω-Propyl-L-arginine hydrochloride
|
Others | Others |
Highly selective and potent inhibitor of nNOS (Ki = 57 nM). Displays 3158-fold and 149-fold selectivity over iNOS and eNOS respectively. Hypotensive in vivo. Kakoki et al (2001) The influence of nitric oxide synthase 1 on blood flow and interstitial nitric oxide in the kidney. Am.J.Physiol.Regul.Integr.Comp.Physiol. 281 R91 PMID:11404282 |Zhang et al (1997) Potent and selective inhibition of neuronal nitric oxide synthase by Nω-propyl-L-arginine. J.Med.Chem. 40 3869 PMID:9397167 | |||
T26351 |
Zofenoprilat arginine
SQ-26,703,SQ 26703,SQ 26,703,SQ-26703,SQ26703 |
Others | Others |
Zofenoprilat arginine is an antihypertensive. | |||
TP1079 |
(Arg)9 TFA (143413-47-2 free base)
Nona-L-arginine (TFA),(Arg)9 TFA,Peptide R9 (TFA) |
Others | Others |
(Arg)9 TFA (Peptide R9 TFA) 是一种可渗透细胞的多肽,在谷氨酸模型实验模型中保护神经(IC50:0.78 μM)。 | |||
T23047 |
N2-Methyl-L-arginine
|
Others | Others |
Selective L-arginine uptake inhibitor | |||
T37802 |
Phospho-L-Arginine (lithium salt hydrate)
|
Others | Others |
Phospho-L-arginine is a phosphorylated form of L-arginine and a highly diffusible, high-energy metabolite and phosphagen involved in energy storage in invertebrates including crustaceans, insects, and Trypanosoma species. In the locust L. migratoria, phospho-L-arginine is found in the flight muscles, where it acts as both a buffer system and shuttle mechanism for high-energy phosphate. Measurement of phospho-L-arginine by 31P-NMR spectroscopy has been used to study invertebrate energy metabolism... | |||
T27818 |
Levonadifloxacin Arginine Salt
WCK 771,WCK-771A,WCK 771A,WCK-771,WCK771A,WCK771 |
Others | Others |
Levonadifloxacin, a broad-spectrum fluoroquinolone antibiotic, is used potentially for the treatment of staphylococci. | |||
T9316 |
JR14a
5-(Bis(4-chlorophenyl)methyl)-3-methylthiophene-2-carbonyl)-l-arginine hydrochloride |
Complement System | Immunology/Inflammation |
JR14a (5-(Bis(4-chlorophenyl)methyl)-3-methylthiophene-2-carbonyl)-l-arginine hydrochloride) 是补体C3a 受体噻吩拮抗剂,可抑制 C3aR 介导的炎症,对人 C3a 受体的选择性高于 C5a 受体。 | |||
T68659 |
Valyl-glycyl-arginine-4-nitroanilide
|
Others | Others |
Valyl-glycyl-arginine-4-nitroanilide is a tissue plasminogen activator. | |||
TP1160 |
Hexa-D-arginine TFA
Furin Inhibitor II TFA |
||
Hexa-D-arginine TFA (Furin Inhibitor II TFA) is an inhibitor of furin (Ki values are 0.106, 0.58 and 13.2 μM for furin, PACE4 and PC1 respectively). | |||
T25684 |
Leucylarginine
Leu-arg,Leucyl-arginine |
Others | Others |
Leucylarginine hinders antinociception induced by L-arginine. | |||
T65772 |
Benzoyl-L-arginine
|
Others | Others |
Benzoyl-L-arginine 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T65772,CAS号为 154-92-7。 | |||
T6570 |
L-NAME hydrochloride
L-NAME HCl,N'-硝基-L-精氨酸甲酯盐酸盐,N(G)-Nitro-L-arginine methyl ester,NG-Nitroarginine methyl ester hydrochloride |
NOS; NO Synthase | Immunology/Inflammation |
L-NAME hydrochloride (L-NAME HCl) 是NOS 抑制剂(IC50:70 μM)。 | |||
T66618 |
DL-Arginine xhydrochloride
|
||
DL-Arginine xhydrochloride 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T66618,CAS号为 32042-43-6。 | |||
T26277L |
Tilarginine citrate
L-Ng-monomethyl arginine citrate |
Others | Others |
Tilarginine citrate is a competitive nitric oxide synthetase inhibitor. | |||
T3443 |
Argiprestocin
精氨缩宫素,Arginine vasotocin |
Others | Others |
Argiprestocin (Arginine vasotocin) 也称为抗利尿激素,在维持渗透压中起关键作用。它是在大多数哺乳动物中发现的一种神经垂体激素。用于引起血管收缩的药物。 | |||
T80096 |
L-Isoleucyl-L-arginine
|
Angiotensin-converting Enzyme (ACE) | Metabolism |
L-Isoleucyl-L-arginine为由L-异亮氨酸和L-精氨酸残基组成的二肽,是一种有效的血管紧张素转换酶(ACE)抑制剂,通常应用于高血压的研究领域。 | |||
T28455 |
ProTAME
pro-Tosyl-L-Arginine Methyl Ester |
Others | Others |
ProTAME is an inhibitor of APC/CFzr and APC/CCdc20. Combinations of proTAME with topoisomerase inhibitors, doxorubicin and etoposide, significantly increase cell death in primary cells and Multiple Myeloma (MM) cell lines, particularly if TOPIIα levels are first increased through pre-treatment with ProTAME.This compound is unstable in powder form and other related salt forms are recommended. | |||
T64447 |
(2,4-Dinitrophenyl)-L-arginine
|
Others | Others |
(2,4-Dinitrophenyl)-L-arginine 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T64447,CAS号为 1602-42-2。 | |||
T76573 |
[8-L-arginine] deaminovasopressin
|
||
[8-L-arginine] deaminovasopressin (dAVP) 是一种抗利尿激素类似物。 | |||
T13976 |
(Arg)9
Peptide R9,Nona-L-arginine |
Others | Others |
(Arg)9 (Nona-L-arginine;Peptide R9) is a cell-penetrating peptide,and exhibits neuroprotective activity(IC50 of 0.78 μM, in the glutamic acid model). | |||
T12240 |
nor-NOHA acetate
Nω-Hydroxy-nor-L-arginine acetate |
Apoptosis; Arginase | Apoptosis; Immunology/Inflammation |
nor-NOHA acetate (Nω-Hydroxy-nor-L-arginine acetate) 是一种可逆的精氨酸酶抑制剂,具有抗白血病的作用,对内皮功能障碍、免疫抑制和代谢有效。在缺氧条件下,它可诱导 ARG2 表达细胞的凋亡。 | |||
T23754 |
Argininamide
L-Arginamide,L-Argininamide,L-Arginine amide |
||
Argininamide is used in studies of the physicochemical characteristic of ligand binding DNA aptamers. | |||
T29598 |
Acetylcarnitine arginyl amide
ST-857,acetyl-L-carnitine arginine amide |
Others | Others |
Acetylcarnitine arginyl amide is able to stimulate neurite outgrowth in a manner similar to that elicited by nerve growth factor (NGF). Neurite induction by this molecule requires de novo mRNA synthesis and is independent of the action of several common t | |||
T32812 |
L-Leucyl-L-prolyl-L-prolyl-L-seryl-L-arginine
H-Leu-Pro-Pro-Ser-Arg-OH |
Others | Others |
L-Leucyl-L-prolyl-L-prolyl-L-seryl-L-arginine is a peptide. | |||
T77998 |
(Arg)9 acetate
Peptide R9 acetate,Nona-L-arginine acetate |
||
(Arg)9 (Nona-L-arginine) acetate 是一种细胞穿透肽(CPP),由9个L-精氨酸残基构成,显示出神经保护作用,其在谷氨酸模型中的IC50值为0.78 μM。 | |||
T83512 |
[1,6-Aminosuberic acid]-arginine-Vasotocin
|
||
[1,6-Aminosuberic acid]-arginine-Vasotocin,一种类似神经垂体激素的合成肽,对黄芪周期性振荡神经元(PON)展现兴奋作用。 | |||
T65690 |
N2-Boc-L-arginine Hydrochloride Hydrate
|
Others | Others |
N2-Boc-L-arginine Hydrochloride Hydrate 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T65690,CAS号为 114622-81-0。 | |||
T25843 |
N(G)-Nitroarginine-4-nitroanilide
NAPNA,N(omega)-Nitro-L-arginine p-nitroanilide,L-Napna |
Others | Others |
N(G)-Nitroarginine-4-nitroanilide is an anti-nociceptive in mice. | |||
T65254 |
N2-(tert-Butoxycarbonyl)-Nw-nitro-D-arginine
|
Others | Others |
N2-(tert-Butoxycarbonyl)-Nw-nitro-D-arginine 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T65254,CAS号为 50913-12-7。 | |||
T83502 |
[Deamino-4-valine, 8-D-arginine]-Vasopressin
dVDAVP |
||
[Deamino-4-valine, 8-D-arginine]-Vasopressin (dVDAVP)为一种抗利尿药,具有高效性、特异性以及延长的药效特点。 | |||
T24982 |
546C88
L-N(G)-Methylarginine hydrochloride,NG-Monomethyl-L-arginine hydrochloride,L-NMMA |
Others | Others |
546C88 is an inhibitor of nitric oxide synthase. |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T0670 |
L-Arginine hydrochloride
(S)-(+)-Arginine hydrochloride,左旋精氨酸单盐酸盐,L-Arginine HCl (L-Arg),L-arginine monohydrochloride |
Amino Acids and Derivatives; Endogenous Metabolite; NO Synthase | Immunology/Inflammation; Metabolism |
L-Arginine hydrochloride 为合成一氧化氮的氮供体,是血管扩张剂。 | |||
T3S0364 |
L-Arginine
L-精氨酸,L-Arg,(S)-(+)-Arginine |
IL Receptor; Endogenous Metabolite; NO Synthase | Immunology/Inflammation; Metabolism |
L-Arginine (L-Arg) 是内皮型一氧化氮合酶(eNOS) 的底物。L-Arginine 通过阳离子氨基酸转运体家族转运到血管平滑肌细胞,并被代谢成一氧化氮、多胺或 L-脯氨酸。 | |||
T19288 |
DL-Arginine
|
Others | Others |
DL-Arginine 是一种额能够用于氨基酸络合动力学和晶体结构的物理化学分析的物质。 | |||
T8053 |
N-Acetyl-L-arginine
N-Α-乙酰-L-精氨酸,Ac-Arg-OH |
Endogenous Metabolite | Metabolism |
N-Acetyl-L-arginine (Ac-Arg-OH) 是一种胍基诺化合物,被发现存在于血液渗析性肾不足儿童患者血清中的。 | |||
T5289 |
N-Acetyl-L-arginine dihydrate
N-Ac-L-arg-OH,乙酰精氨酸 |
Others; Endogenous Metabolite | Metabolism; Others |
N-Acetyl-L-arginine dihydrate (N-Ac-L-arg-OH) 是内源性代谢产物的一种。 | |||
T13307 |
Vitexin arginine
|
Others | Others |
Vitexin arginine is a natural c-glycosylated flavone isolated from various medicinal plants species,with anti-oxidant, anti-cancer, anti-inflammatory, anti-hyperalgesic, and neuroprotective effects. | |||
T7344 |
SDMA
NG,NG'-Dimethyl-L-arginine,Symmetric dimethylarginine,对称N,N-二甲基精氨酸 |
Endogenous Metabolite | Metabolism |
SDMA (Symmetric dimethylarginine) 是一氧化氮 (NO) 合酶的内源性抑制剂。 | |||
T20262 |
Arginine glutamate
Modumate,NSC-122009,NSC 122009,NSC122009,NCI-C02120,Argimate |
Others | Others |
Arginine glutamate is an agent of ammonia Detoxicant. | |||
T21296 |
Desmopressin acetate trihydrate
Desmogalen,Adiuretin,Deamino Arginine Vasopressin,Vasopressin 1-Desamino-8-arginine |
||
Desmopressin acetate is a synthetic replacement for vasopressin, which reduces urine production. Medical use of Desmopressin acetate includes: (a) bed wetting; (b) diabetes insipidus; (c) nighttime urination; (d) clotting disorders. | |||
T2205 |
Acefylline
Theophylline-7-acetic acid,茶碱乙酸,Carboxymethyltheophylline,acetyloxytheophylline,Theophyllineacetic acid |
TNF; PAD; PKA; HDAC; PDE; Adenosine Receptor | Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair; GPCR/G Protein; Metabolism; Neuroscience; Tyrosine Kinase/Adaptors |
Acefylline (Theophylline-7-acetic acid) 是黄嘌呤衍生物,是一种腺苷受体拮抗剂。它是蛋白质精氨酸脱亚氨酶 (PAD) 激活剂,也是一种支气管扩张剂,可抑制大鼠肺 cAMP 磷酸二酯酶同工酶。 | |||
T7682 |
Asymmetric dimethylarginine
|
Endogenous Metabolite; NO Synthase; NOD | Immunology/Inflammation; Metabolism; NF-κB |
Asymmetric dimethylarginine 是内源性一氧化氮合成酶抑制剂,可以作为内皮功能障碍的标志。 | |||
T4813 |
L-Citrulline
|
Endogenous Metabolite | Metabolism |
L-Citrulline 是一种氨基酸,源自于精氨酸-瓜氨酸途径获得的 l-精氨酸,或脯氨酸、谷氨酰胺和谷氨酸盐的分解代谢过程中产生的鸟氨酸。 | |||
T8103 |
H-HoArg-OH
|
Endogenous Metabolite; Phosphorylase | Metabolism |
H-HoArg-OH 是人骨和肝脏碱性磷酸酶(alkaline phosphatase)的强效抑制剂,是一种精氨酸的同系物。 | |||
T2A2498 |
L-Lysine
Aminutrin,Lysine Acid,lysine,L-赖氨酸,赖氨酸 |
Virus Protease; Endogenous Metabolite; Antifection | Metabolism; Microbiology/Virology |
L-Lysine (Aminutrin) 是一种人类必需氨基酸,能增加钙吸收,减少糖尿病相关疾病和改善肠道健康,可用于疱疹的研究。 | |||
T2931 |
2-Amino-5-ureidopentanoic acid
DL-Citrulline,Citrulline,瓜氨酸 |
Others; Endogenous Metabolite | Metabolism; Others |
2-Amino-5-ureidopentanoic acid (Citrulline) 存在于肝脏中,不是蛋白质的构成成分,为人体脲循环的一个重要中间物,可与鸟氨酸、精氨酸合用治疗高氨血症。 | |||
T4927 |
4-Guanidinobutanoic acid
4-GBA,4-胍基丁酸,4-Guanidinobutyric acid |
Endogenous Metabolite | Metabolism |
4-Guanidinobutanoic acid (4-GBA) 是一种 L-精氨酸代谢物,已用于肠道转运研究。 它已专门用于人质子偶联氨基酸转运蛋白 hPAT1。 | |||
T2O2731 |
L-Aspartic acid
L-天冬氨酸,L-天冬氨酸;L-天冬碱;L-酰胺天冬酸;L-天冬酰胺一水物,Aspatofort,Asparagic acid |
Others; Endogenous Metabolite | Metabolism; Others |
L-Aspartic acid (Aspatofort) 是一种氨基酸,是结肠特异性药物输送的前体药物。 | |||
T4238 |
Glycocyamine
乙酸胍,2-Guanidinoacetic acid,Guanidoacetic acid |
Others; Endogenous Metabolite | Metabolism; Others |
Glycocyamine (2-Guanidinoacetic acid) 是一种肌酸的前体,能够为鸟类的体内平衡提供能量,也能够成为食用精氨酸的替代物。 | |||
T4808 |
Agmatine sulfate
Agmatine sulfate salt,硫酸胍基丁胺 |
Endogenous Metabolite; NO Synthase; Imidazoline Receptor | Immunology/Inflammation; Metabolism; Neuroscience |
Agmatine sulfate (Agmatine sulfate salt) 是咪唑啉受体的内源性激动剂和一氧化氮合酶抑制剂。它靶向神经递质系统,离子通道和一氧化氮合成。 | |||
TN6872 |
Trypsin
|
Protease-activated Receptor | GPCR/G Protein |
Trypsin 是一种可从鱼类分离出的丝氨酸蛋白酶,可水解赖氨酸或精氨酸羧基侧蛋白质。Trypsin 具有抗炎活性,可通过 PDCoV 的 S 糖蛋白与 pAPN 的相互作用诱导 PDCoV 感染的细胞膜融合,可激活 PAR2 和 PAR4,促进细胞增殖和分化。Trypsin 可用于促进伤口愈合和研究神经源性炎症。 | |||
T4883 |
Creatine
Methylguanidoacetic acid,肌酸 |
Endogenous Metabolite | Metabolism |
Creatine (Methylguanidoacetic acid) 是一种内源性氨基酸代谢物,在细胞能量中发挥重要作用,尤其是在肌肉和大脑中。 | |||
TN3972 |
Epimedokoreanin B
|
Apoptosis; Others; Antibacterial | Apoptosis; Microbiology/Virology; Others |
Epimedokoreanin B (EKB) 是一种从韩国淫羊藿中分离出的异戊烯化类黄酮,在人非小细胞肺癌(NSCLC)A549和NCI-H292细胞中展现出抗癌活性。Epimedokoreanin B 还具有抗炎和抗菌活性,可有清除 DPPH 自由基的活性,能以剂量依赖的方式抑制 MCF-7 和 HepG2 的增殖。Epimedokoreanin B 能显著抑制 N (δ) -(羧甲基)赖氨酸(CML)和 N (Ï) -(羧甲基)精氨酸(CMA)的形成,可通过抑制高级糖化终产物(AGEs)预防糖尿病的临床并发症。 | |||
T15350 |
Fructosyl-lysine
Fructoselysine,果糖-赖氨酸 |
Others | Others |
Fructosyl-lysine is the precursor to glucosepane. Fructosyl-lysine is a lysine–arginine protein cross-link that can be an indicator in diabetes detection. Fructosyl-lysine is an amadori glycation product from the reaction of glucose and lysine by the Maillard reaction. | |||
TN5186 |
Triptoquinone A
|
IL Receptor; NOS | Immunology/Inflammation |
Triptoquinone A may be a useful candidate for the development of a drug as a potent inhibitor of iNOS gene over-expression. Triptoquinone A has anti-inflammatory activity, it prevents ndotoxin-or interleukin-1 beta-promoted induction of nitric oxide synth |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-03088 |
Arginine kinase/AK Protein, Penaeus monodon, Recombinant (His & SUMO)
Pen m 2,AK,Arginine kinase |
Penaeus monodon | E. coli |
N/A. Arginine kinase/AK Protein, Penaeus monodon, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 56.0 kDa and the accession number is C7E3T4. | |||
TMPY-00021 |
PADI4 Protein, Human, Recombinant (His)
PADI5,PAD4,PDI4,peptidyl arginine deiminase, type I... |
Human | Baculovirus Insect Cells |
Protein-arginine deiminase type-4, also known as HL-6 PAD, Peptidylarginine deiminase IV, Protein-arginine deiminase type I V and PADI4, is a cytoplasm and nucleus protein that belongs to the protein arginine deiminase family. PADI4 is expressed in CD34+stem cells in normal tissues, and many more CD34+ cells expressing PADI4 are present in tumour tissues. PADI4 post-translationally converts peptidylarginine to citrulline, a process called citrullination. Studies have demonstrated the high expres... | |||
TMPH-03769 |
ADI Protein, Metamycoplasma hominis, Recombinant (His)
arcA,Arginine dihydrolase,ADI,Arginine dei... |
Metamycoplasma hominis | HEK293 |
ADI Protein, Metamycoplasma hominis, Recombinant (His) is expressed in HEK293 expression system. The predicted molecular weight is 48.0 kDa and the accession number is P41141. | |||
TMPY-01383 |
PRMT6 Protein, Human, Recombinant (His & Flag)
protein arginine methyltransferase 6,HRMT1L6 |
Human | HEK293 Cells |
Protein arginine N-methyltransferase 6, also known as Histone-arginine N-methyltransferase PRMT6, PRMT6, and HRMT1L6, is a member of the protein arginine N-methyltransferase family and PRMT6 subfamily. PRMT6 is highly expressed in kidney and testes. PRMT6 is known to catalyze the generation of asymmetric dimethylarginine in polypeptides. It has been implicated in human immunodeficiency virus pathogenesis, DNA repair, and transcriptional regulation. PRMT6 is known to methylate histone H3 Arg-2 (H... | |||
TMPH-00591 |
SpeA Protein, E. coli, Recombinant (His)
speA,Biosynthetic arginine decarboxylase |
E. coli | E. coli |
Catalyzes the biosynthesis of agmatine from arginine. | |||
TMPY-01270 |
PRMT3 Protein, Human, Recombinant (GST)
HRMT1L3,protein arginine methyltransferase 3 |
Human | E. coli |
Protein arginine methyltransferase 3, also known as PRMT3, is one of four type I protein arginine methyltransferases (PRMT) that in humans is encoded by the PRMT3 gene. Methylation of arginine residues is a widespread post-translational modification of proteins catalyzed by a small family of PRMTs. The modification appears to regulate protein functions and interactions that affect gene regulation, signalling and subcellular localization of proteins and nucleic acids. In human cells, the PRMT fam... | |||
TMPH-01967 |
PADI3 Protein, Human, Recombinant (His)
Protein-arginine deiminase type III,Peptidylarg... |
Human | P. pastoris (Yeast) |
PADI3 Protein, Human, Recombinant (His) is expressed in Yeast. | |||
TMPH-01965 |
PADI2 Protein, Human, Recombinant (His & Myc)
Protein-arginine deiminase type-2,PADI2,Peptidyl |
Human | HEK293 Cells |
PADI2 Protein, Human, Recombinant (His & Myc) is expressed in HEK293. | |||
TMPH-01966 |
PADI2 Protein, Human, Recombinant (His & SUMO)
Peptidylarginine deiminase II,Protein-arginine<... |
Human | E. coli |
PADI2 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli. | |||
TMPH-02086 |
SRSF3 Protein, Human, Recombinant (GB1 & His)
Serine/arginine-rich splicing factor 3,Pre-mRNA-spl... |
Human | E. coli |
SRSF3 Protein, Human, Recombinant (GB1 & His) is expressed in E. coli. | |||
TMPJ-00532 |
PADI4 Protein, Human, Recombinant (E. coli, His)
PDI5,PADI4,Protein-arginine Deiminase type IV,HL-60... |
Human | E. coli |
Protein-Arginine Deiminase Type-4 (PADI4) belongs to the Protein Arginine Deiminase family. PADI4 is expressed in eosinophils and neutrophils, but it is not expressed in peripheral monocytes or lymphocytes. PADI4 catalyzes the citrullination/deimination of arginine residues of proteins. In addition, PADI4 may play an important role in tumourigenesis. Genetic variations in PADI4 are a cause of susceptibility to rheumatoid arthritis (RA), which is a systemic inflammatory disease with autoimmune fe... | |||
TMPH-00482 |
Arginine esterase Protein, Canine, Recombinant (His & SUMO)
|
Canine | E. coli |
Arginine esterase Protein, Canine, Recombinant (His & SUMO) is expressed in E. coli. | |||
TMPH-02085 |
SRSF1 Protein, Human, Recombinant (His & SUMO)
Alternative-splicing factor 1,Splicing factor, arginine<... |
Human | E. coli |
SRSF1 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli. | |||
TMPY-00571 |
PRELP Protein, Human, Recombinant (mFc)
proline/arginine-rich end leucine-rich repeat prote... |
Human | HEK293 Cells |
PRELP Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 68.3 kDa and the accession number is P51888. | |||
TMPY-00572 |
PRELP Protein, Human, Recombinant
proline/arginine-rich end leucine-rich repeat prote... |
Human | HEK293 Cells |
PRELP Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 41.8 kDa and the accession number is P51888. | |||
TMPH-02084 |
SRRM2 Protein, Human, Recombinant (His & Myc)
Splicing coactivator subunit SRm300,SRRM2,Serine/arginin... |
Human | Baculovirus Insect Cells |
SRRM2 Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus. | |||
TMPH-03132 |
AVPR2 Protein, Pig, Recombinant (His & SUMO)
AVPR2,Vasopressin V2 receptor,V2R,AVPR V2,Antidiuretic hormo... |
Sus scrofa (Pig) | E. coli |
Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Involved in renal water reabsorption. AVPR2 Protein, Pig, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 24.7 kDa and the accession number is P32307. | |||
TMPK-01238 |
PADI4 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated
PDI5,Protein-arginine deiminase type-4,HL-60,PAD4,H... |
Human | E. coli |
Peptidylarginine deiminase type4 (PADI4) was firstly identified as a non-MHC RA genetic risk factor. Furthermore, PADI4 risk allele possessed the association with bone damage regardless of anti citrullinated peptide antibody (ACPA) positivity in Asian RA patients. PADI4 gene codes PAD4 protein which has post-translational modification activity (citrullination). Padi4 is mainly expressed in myeloid cells and granulocytes. PADI4 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinyla... | |||
TMPK-00501 |
PADI4 Protein, Cynomolgus, Recombinant (His)
Protein-arginine deiminase type-4,HL60 PAD,PAD,PDI5... |
Cynomolgus | E. coli |
Peptidylarginine deiminase type4 (PADI4) was firstly identified as a non-MHC RA genetic risk factor. Furthermore, PADI4 risk allele possessed the association with bone damage regardless of anti citrullinated peptide antibody (ACPA) positivity in Asian RA patients. PADI4 gene codes PAD4 protein which has post-translational modification activity (citrullination). Padi4 is mainly expressed in myeloid cells and granulocytes. PADI4 Protein, Cynomolgus, Recombinant (His) is expressed in E. coli expres... | |||
TMPH-02228 |
TRA2B Protein, Human, Recombinant (His & Myc)
TRA2B,Transformer-2 protein homolog B,Splicing factor, a... |
Human | Baculovirus Insect Cells |
Sequence-specific RNA-binding protein which participates in the control of pre-mRNA splicing. Can either activate or suppress exon inclusion. Acts additively with RBMX to promote exon 7 inclusion of the survival motor neuron SMN2. Activates the splicing of MAPT/Tau exon 10. Alters pre-mRNA splicing patterns by antagonizing the effects of splicing regulators, like RBMX. Binds to the AG-rich SE2 domain in the SMN exon 7 RNA. Binds to pre-mRNA. | |||
TMPH-02229 |
TRA2B Protein, Human, Recombinant (His & SUMO)
TRA2B,Transformer-2 protein homolog B,Splicing factor, a... |
Human | E. coli |
Sequence-specific RNA-binding protein which participates in the control of pre-mRNA splicing. Can either activate or suppress exon inclusion. Acts additively with RBMX to promote exon 7 inclusion of the survival motor neuron SMN2. Activates the splicing of MAPT/Tau exon 10. Alters pre-mRNA splicing patterns by antagonizing the effects of splicing regulators, like RBMX. Binds to the AG-rich SE2 domain in the SMN exon 7 RNA. Binds to pre-mRNA. TRA2B Protein, Human, Recombinant (His & SUMO) is expr... | |||
TMPK-00502 |
PADI4 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated
PDI5,HL-60,PAD,PADI5,Protein-arginine deiminase typ... |
Cynomolgus | E. coli |
Peptidylarginine deiminase type4 (PADI4) was firstly identified as a non-MHC RA genetic risk factor. Furthermore, PADI4 risk allele possessed the association with bone damage regardless of anti citrullinated peptide antibody (ACPA) positivity in Asian RA patients. PADI4 gene codes PAD4 protein which has post-translational modification activity (citrullination). Padi4 is mainly expressed in myeloid cells and granulocytes. PADI4 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biot... | |||
TMPH-01732 |
DDAH1 Protein, Human, Recombinant (His & Myc)
DDAHI,N(G),N(G)-dimethylarginine dimethylaminohydro... |
Human | E. coli |
Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation. DDAH1 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 38.4 kDa and the accession number is O94760. | |||
TMPH-02343 |
Hypodermin-A Protein, Hypoderma lineatum, Recombinant (His)
Hypodermin-A |
Hypoderma lineatum | E. coli |
Specificity, limited to carboxyl side of arginine residue in B-chain of insulin. | |||
TMPJ-01058 |
ARG2 Protein, Human, Recombinant (His)
ARG2,Kidney-type arginase,Type II arginase,Arginase-2, mitoc... |
Human | E. coli |
Arginase-2 (ARG2) is a member of the arginase family. Arginase is a manganese-containing enzyme which catalyzes the hydrolysis of arginine to ornithine and urea. ARG2 is highly expressed in kidney and prostate, not founded in the liver, heart and pancreas. ARG2 has been implicated in the regulation of the arginine/ornithine concentrations in the cell. ARG2 may take part in the regulation of extra-urea cycle arginine metabolism and in down-regulation of nitric oxide synthesis. The extrahepatic ar... | |||
TMPH-01733 |
DDAH2 Protein, Human, Recombinant (GST & His)
Inactive dimethylarginine dimethylaminohydrolase 2,... |
Human | E. coli |
Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation. DDAH2 Protein, Human, Recombinant (GST & His) is expressed in E. coli expression system with N-6xHis-GST tag. The predicted molecular weight is 61.2 kDa and the accession number is O95865. | |||
TMPY-03386 |
ART3 Protein, Human, Recombinant (His)
ADP-ribosyltransferase 3,ARTC3 |
Human | HEK293 Cells |
ART3 is an arginine-specific ADP-ribosyltransferase which belongs to the Arg-specific ADP-ribosyltransferase family. ART3 catalyzes a reversible reaction which modifies proteins by the addition or removal of ADP-ribose to an arginine residue to regulate the function of the modified protein. It is expressed specifically in testis. ART3 pseudogene is located on chromosome 11. ART3 was identified as a susceptibility gene for non-obstructive azoospermia (NOA). It is a novel therapeutic target in the... | |||
TMPH-02526 |
Arginase-2/ARG2 Protein, Mouse, Recombinant (His & SUMO)
Arginase II,Kidney-type arginase,Type II arginase,Arg2,Argin... |
Mouse | E. coli |
May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis. Extrahepatic arginase functions to regulate L-arginine bioavailability to nitric oxid synthase (NOS). Arginine metabolism is a critical regulator of innate and adaptive immune responses. Seems to be involved in negative regulation of the survival capacity of activated CD4(+) and CD8(+) T cells. May suppress inflammation-related signaling in asthmatic airway epithelium.... | |||
TMPH-02524 |
Arginase-1/ARG1 Protein, Mouse, Recombinant (His)
Arginase-1,Type I arginase,Liver-type arginase,Arg1 |
Mouse | P. pastoris (Yeast) |
Key element of the urea cycle converting L-arginine to urea and L-ornithine, which is further metabolized into metabolites proline and polyamides that drive collagen synthesis and bioenergetic pathways critical for cell proliferation, respectively; the urea cycle takes place primarily in the liver and, to a lesser extent, in the kidneys.; Functions in L-arginine homeostasis in nonhepatic tissues characterized by the competition between nitric oxide synthase (NOS) and arginase for the available i... | |||
TMPJ-00732 |
ASS1 Protein, Human, Recombinant (His)
Citrulline--Aspartate Ligase,Argininosuccinate Synthase,ASS1... |
Human | E. coli |
Argininosuccinate Synthase (ASS1) is an urea cycle enzyme with a tetrameric structure composed of identical subunits. ASS1 is involved in the synthesis of arginine and catalyzes that condensation of citrulline and aspartate to argininosuccinate using ATP. ASS1 is important to the urea cycle as it catalyzes the important second last step in the arginine biosynthetic pathway. ASS1 mainly expressed in periportal hepatocytes, but also in most other body tissues. A deficiency of ASS1 causes citrullin... | |||
TMPH-03087 |
ODH1 Protein, Pecten maximus, Recombinant (His & Myc)
Octopine dehydrogenase,odh1 |
Pecten maximus | E. coli |
Catalyzes the reverse reaction of octopine dehydrogenation. Acts on L-arginine in preference to other substrates such as canavanine, cysteine, L-alanine, ornithine or norvaline, owing to the presence of the positively charged guanidium group. ODH1 Protein, Pecten maximus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 50.8 kDa and the accession number is Q9BHM6. | |||
TMPY-04565 |
SRPK3 Protein, Human, Recombinant (His & GST)
MSSK1,MGC102944,STK23,MSSK-1,SRSF protein kinase 3 |
Human | Baculovirus Insect Cells |
Serine / threonine-protein kinase SRPK3, also known as Muscle-specific serine kinase 1, Serine/arginine-rich protein-specific kinase 3, SR-protein-specific kinase 3, Serine / threonine-protein kinase 23, MSSK-1, SRPK3 and MSSK1, is a member of the protein kinase superfamily and CMGC Ser / Thr protein kinase family. SRPK3 is a protein kinase belonging to serine/arginine protein kinases (SRPK) family, which phosphorylates serine / arginine repeat-containing proteins, and is controlled by a muscle-... | |||
TMPY-03172 |
Argininosuccinate lyase Protein, Human, Recombinant (His & GST)
ASAL,argininosuccinate lyase,ASL |
Human | Baculovirus Insect Cells |
The recycling of citrulline by argininosuccinate synthase 1 (ASS1) and argininosuccinate lyase (ASL) is crucial to maintain arginine availability and nitric oxide (NO) production. Nitric oxide (NO) plays an established role in numerous physiological and pathological processes, but the specific cellular sources of NO in disease pathogenesis remain unclear, preventing the implementation of NO-related therapy. Argininosuccinate lyase (ASL) is the only enzyme able to produce arginine, the substrate ... | |||
TMPH-03158 |
PAD Protein, Porphyromonas gingivalis, Recombinant (His)
Peptidylarginine deiminase |
Porphyromonas gingivalis | E. coli |
Deiminates the guanidino group of C-terminal arginine residues on a variety of peptides, including the vasoregulatory peptide-hormone bradykinin, to yield ammonia and a citrulline residue. May promote the growth of the pathogen in the periodontal pocket by producing ammonia, ammonia having a protective effect during acidic cleaning cycles in the mouth. PAD Protein, Porphyromonas gingivalis, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weig... | |||
TMPH-02527 |
ASS1 Protein, Mouse, Recombinant (His & Myc)
Ass,Citrulline--aspartate ligase,Ass1,Argininosuccinate synt... |
Mouse | E. coli |
One of the enzymes of the urea cycle, the metabolic pathway transforming neurotoxic amonia produced by protein catabolism into inocuous urea in the liver of ureotelic animals. Catalyzes the formation of arginosuccinate from aspartate, citrulline and ATP and together with ASL it is responsible for the biosynthesis of arginine in most body tissues. ASS1 Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 5... | |||
TMPK-00191 |
PILRA Protein, Mouse, Recombinant (hFc)
PILR-α,FDF03,PILRA,PILR-alpha,PILRalpha,PILRα |
Mouse | HEK293 Cells |
Alzheimer's disease (AD) is a neurodegenerative disease characterized by a progressive decline in cognitive performance; Mild Cognitive Impairment (MCI) is instead an objective decline in cognitive performance that does not reach pathology. Paired immunoglobulin-like type 2 receptor alpha (PILRA) is a cell surface inhibitory receptor that was recently suggested to be involved in AD pathogenesis. In particular, the arginine-to-glycine substitution in position 78 (R78, rs1859788) was shown to be p... | |||
TMPY-00583 |
ADPRH Protein, Human, Recombinant (His)
ADP-ribosylarginine hydrolase,ARH1 |
Human | E. coli |
Cholera toxin (CT) produced by Vibrio cholerae causes the devastating diarrhea of cholera by catalyzing the ADP-ribosylation of the alpha subunit of the intestinal Gs protein (Gsalpha), leading to characteristic water and electrolyte losses. Mammalian cells contain ADP-ribosyltransferases similar to CT and an ADP-ribosyl(arginine)protein hydrolase (ADPRH), which cleaves the ADP-ribose-(arginine)protein bond, regenerating native protein and completing an ADP-ribosylation cycle. CT-catalyzed ADP-r... | |||
TMPJ-00649 |
CPB2 Protein, Human, Recombinant (His)
CPB2,CPU,TAFI,pCPB,Carboxypeptidase B2,Plasma Carboxypeptida... |
Human | HEK293 Cells |
Carboxypeptidase B2 (CPB2) is a secreted enzyme that belongs to the peptidase M14 family. CPB2 is synthesized by the liver and circulates in the plasma as a plasminogen-bound zymogen by the liver and circulates in the plasma as a plasminogen-bound zymogen. CPB2 cleaves C-terminal arginine or lysine residues from biologically active peptides, such as kinins or anaphylatoxins, in the circulation regulating their activities. CPB2 also down-regulates fibrinolysis by removing C-terminal lysine residu... | |||
TMPY-00992 |
ERAP2 Protein, Human, Recombinant (His)
L-RAP,endoplasmic reticulum aminopeptidase 2,FLJ23633,LRAP.E... |
Human | HEK293 Cells |
Leukocyte-derived arginine aminopeptidase (LRAP), also known as endoplasmic reticulum-aminopeptidase 2 (ERAP2), is the second identified aminopeptidase localized in the in the lumenal side of endoplasmic reticulum (ER) processing antigenic peptides presented to major histocompatibility complex (MHC) class I molecules. It is a 96-amino acid protein with significant homology to placental leucine aminopeptidase and adipocyte-derived leucine aminopeptidase. LRAP preferentially hydrolyz... | |||
TMPJ-01114 |
GAMT Protein, Human, Recombinant (His)
Guanidinoacetate N-methyltransferase,TP53I2,PIG2,GAMT |
Human | E. coli |
GAMT is a methyltransferase which belongs to the class I-like SAM-binding methyltransferase superfamily. It contains one RMT2 (arginine N-methyltransferase 2-like) domain and is expressed in liver. GAMT converts guanidoacetate to creatine, using S-adenosylmethionine as the methyl donor. Defects in GAMT are the cause of guanidinoacetate methyltransferase deficiency, which is an autosomal recessive disorder characterized by developmental delay/regression, mental retardation, severe disturbance of ... | |||
TMPJ-01320 |
BSSP-4 Protein, Human, Recombinant (His)
BSSP4,Tryptase ε,Serine Protease 26,BSSP-4,Serine Protease 2... |
Human | HEK293 Cells |
Brain-Specific Serine Protease 4 (BSSP-4) is a serine protease that preferentially cleaves the synthetic substrate H-D-Leu-Thr-Arg-pNA compared to tosyl-Gly-Pro-Arg-pNA. BSSP-4 is expressed abundantly in the epithelial cells of the airways, including trachea, esophagus and fetal lung, but scarce in adult lung and expressed at low levels in placenta, pancreas, prostate and thyroid gland. BSSP-4 belongs to the peptidase S1 family and related to trypsin, referentially hydrolyzing substrates after a... | |||
TMPH-01240 |
MCM2 Protein, Human, Recombinant (His)
DNA replication licensing factor MCM2,Nuclear protein BM28,M... |
Human | E. coli |
Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active ... | |||
TMPY-04770 |
RIOK1 Protein, Human, Recombinant (His & GST)
AD034,RRP10,bA288G3.1,RIO kinase 1 |
Human | Baculovirus Insect Cells |
RIOK1, also known as RIO kinase 1, is a member of the RIO family of atypical serine protein kinases first characterized in yeast. RIOK1 and RIOK2 proteins are present in organisms from Archaea to humans. RIOK1 functions as a new interactor of protein arginine methyltransferase 5 (PRMT5), competes with pICln for binding and modulates PRMT5 complex composition and substrate specificity. RioK1 and pICln bind to PRMT5 in a mutually exclusive fashion. This results in a PRMT5-WD45/MEP5 core structure ... | |||
TMPY-04546 |
CLK3 Protein, Human, Recombinant (GST)
PHCLK3,CDC-like kinase 3,PHCLK3/152 |
Human | Baculovirus Insect Cells |
Dual specificity protein kinase CLK3, also known as CDC-like kinase 3, and CLK3, is a member of CMGC Ser/Thr protein kinase family and Lammer subfamily. Mammalian CLK is the prototype for a family of dual specificity kinases (termed Lammer kinases) that have been conserved in evolution. CLK family members have shown to interact with, and phosphorylate, serine- and arginine-rich (SR) proteins of the spliceosomal complex, which is a part of the regulatory mechanism that enables the SR prote... | |||
TMPY-01635 |
PCSK1 Protein, Human, Recombinant (His)
proprotein convertase subtilisin/kexin type 1,SPC3,PC1,BMIQ1... |
Human | HEK293 Cells |
Neuroendocrine convertase 1, also known as Prohormone convertase 1, Proprotein convertase 1, PCSK1 and NEC1, is an enzyme which belongs to the peptidase S8 family and Furin subfamily. PCSK1 is an enzyme that performs the proteolytic cleavage of prohormones to their intermediate (or sometimes completely cleaved) forms. It is present only in neuroendocrine cells such as brain, pituitary and adrenal, and most often cleaves after a pair of basic residues within prohormones but can occasionally cleav... | |||
TMPY-04567 |
SRPK1 Protein, Human, Recombinant (His & GST)
SRSF protein kinase 1,SFRSK1,RP3-422H11.1 |
Human | Baculovirus Insect Cells |
Serine / threonine-protein kinase SRPK1, also known as SFRS protein kinase 1, Serine/arginine-rich protein-specific kinase 1, SR-protein-specific kinase 1 and SRPK1, is a cytoplasm and nucleus protein that belongs to the protein kinase superfamily and CMGC Ser/Thr protein kinase family. Isoform 2 of SRPK1 is predominantly expressed in the testis but is also present at lower levels in heart, ovary, small intestine, liver, kidney, pancreas and skeletal muscle. Isoform 1 of SRPK1 is only seen in th... | |||
TMPJ-00605 |
GPVI Protein, Mouse, Recombinant (His)
Glycoprotein 6,GP6,glycoprotein VI (platelet),GPVI,GPIV,MGC1... |
Mouse | HEK293 Cells |
Glycoprotein VI (GPVI) is a 63 kDa platelet/megakaryocyte-specific type I transmembrane glycoprotein of the immunoglobulin superfamily that is an important collagen receptor and initiator of platelet activation, aggregation and thrombin generation. GPVI is also a secondary receptor required for platelet spreading on laminin. GPVI associates with the Fc receptor gamma -chain via charged aa in the TM domains of GPVI (arginine) and the FcR gamma (aspartic acid). Collagen binding by the GPVI Ig-like... |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T39441 |
L-Arginine-15N4 hydrochloride
L-Arginine-15N4 hydrochloride,(S)-(+)-Arginine-15N4 hydrochloride |
||
L-Arginine-15N4 ((S)-(+)-Arginine-15N4) hydrochloride, the 15N-labeled variant of L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride), serves as the nitrogen donor in the synthesis of nitric oxide. This potent vasodilator is crucial, especially during a sickle cell crisis where its levels are notably diminished. | |||
TMIH-0361 |
N,N'-Dimethylarginine-d6
|
||
N,N'-Dimethylarginine-d6 是 N,N'-Dimethylarginine 的氘代化合物。N,N'-Dimethylarginine 的 CAS 号为 30344-00-4。SDMA 是一氧化氮 (NO) 合酶的内源性抑制剂。 | |||
T70990 |
ADMA-d6
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NG,NG-dimethyl-L-arginine-d6 (ADMA-d6) (hydrochloride) is intended for use as an internal standard for the quantification of NG,NG-dimethyl-L-arginine by GC- or LC-MS. ADMA is an endogenous inhibitor of nitric oxide synthase (NOS). It is formed from arginine by protein arginine methyltransferases (PRMTs) and degraded by dimethylarginine dimethylaminohydrolases (DDAHs) and alanine-glyoxylate aminotransferase 2 (AGXT2). ADMA levels are increased concomitant with an increase in blood pressure in Da... |