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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T71596 |
Bag-2
|
Others | Others |
Bag-2 is a Novel potent, non-peptidic bombesin receptor subtype-3 (BRS-3) agonist. |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPJ-00717 |
BAG2 Protein, Human, Recombinant (His)
BAG-2,BAG Family Molecular Chaperone Regulator 2,BAG2,Bcl-2-... |
Human | E. coli |
BAG Family Molecular Chaperone Regulator 2 (BAG2) is a member of the Bag family whose members compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. BAG2 contains 1 BAG domain and is a important component of the HSC 70/CHIP chaperone-dependent ubiquitin ligase complex. In mammalian cells BAG1, BAG2, and BAG3 bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. |