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Search Results for " amaryllidaceae "

Targets Recommended: Others

2

抑制剂 & 化合物

38

天然产物

1

化合物库

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Cat. No.	Product Name
L6110	生物碱类天然产物库		500 compounds
	500 种生物碱类天然产物的独特集合，可用于高通量筛选和高内涵筛选；

化合物库

生物碱类天然产物库

Cat.No: L6110

Compounds: 500

Cat. No.	Product Name	Target	Signaling Pathways
T11534L	Haemanthamine hydrochloride (466-75-1 free base) Haemanthamine hydrochloride	Others	Others
	Haemanthamine hydrochloride is an alkaloid isolated from the Amaryllidaceae plants with potent anticancer activity. It inhibits protein biosynthesis during the elongation stage of translation. It has antimalarial, pro-apoptotic, antiviral, antioxidant, an
T74017	N-Methylhemeanthidine chloride	Others	Others
	N-Methylhemeanthidine chloride 是一种单孢菌科生物碱，从 Zephyranthes candida 中分离得到。N-Methylhemeanthidine chloride 具有抗肿瘤活性，可以通过下调 AKT 的活化，介导细胞周期阻滞、诱导细胞凋亡 (apoptosis)，抑制癌细胞增殖。

化合物

Haemanthamine hydrochloride (466-75-1 free base)

Cat.No: T11534L

Synonym: Haemanthamine hydrochloride

Target: Others

N-Methylhemeanthidine chloride

Cat.No: T74017

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T3324	Lycorine Galanthidine,Narcissine,石蒜碱,Amarylline,Belamarine,Licorine,番石榴碱	Apoptosis; Virus Protease; Antibacterial; AChR; Fatty Acid Synthase	Apoptosis; Metabolism; Microbiology/Virology; Neuroscience
	Lycorine (Narcissine) 是从金眼科植物科中提取的一种天然生物碱。它是一种具有口服活性的SCAP 抑制剂，Kd 值 15.24 nM。它也是黑色素瘤血管生成抑制剂，有用于前列腺癌和代谢疾病的研究潜力。
TN3732	Curculigoside C	Others	Others
	Curculigoside C是一种天然产物，属于石蒜科仙茅属，其产品编号为 TN3732，CAS号为 851713-74-1。Curculigoside C可用作对照参考。
T11534	Haemanthamine	Others	Others
	Haemanthamine is an alkaloid isolated from the Amaryllidaceae plants with potent anticancer activity. It inhibits protein biosynthesis during the elongation stage of translation. It has antimalarial, pro-apoptotic, antiviral, antioxidant, and anticonvulsa
TN3072	5-Hydroxy-3-(4-hydroxybenzyl)-7-methoxychroman-4-one 4H-1-Benzopyran-4-one,2,3-dihydro-5-hydroxy-3-[(4-hydroxyphenyl)methyl]-7-methoxy-	Others	Others
	5-Hydroxy-3-(4-hydroxybenzyl)-7-methoxychroman-4-one是一种天然产物，属于石蒜科龙舌兰属，其产品编号为 TN3072，CAS号为 108001-32-7。5-Hydroxy-3-(4-hydroxybenzyl)-7-methoxychroman-4-one可用作对照参考。
T73813	Haemanthamine hydrochloride	Others	Others
	Haemanthamine hydrochloride 是从Amaryllidaceae 植物中分离出来的一种蛇毒碱样生物碱，具有强大的抗癌活性。Haemanthamine hydrochloride 靶向核糖体以在翻译的延长阶段抑制蛋白质的生物合成。Haemanthamine hydrochloride 具有促凋亡，抗氧化剂，抗病毒，抗疟疾和抗惊厥活性。
T3758	2,6-Dimethoxybenzoic acid	Others; Endogenous Metabolite; Antifungal	Metabolism; Microbiology/Virology; Others
	2,6-Dimethoxybenzoic acid 是一种邻甲氧苯甲酸及其衍生物，抑制真菌和细菌。
T4S1725	Galanthamine Galantamine,加兰他敏	Apoptosis; AChE	Apoptosis; Neuroscience
	Galanthamine (Galantamine) 是一种乙酰胆碱酯酶抑制剂，IC50为 500 nM。
T3748	orcinol 5-Methylresorcinol,苔黑素、苔黑酚、地衣酚,3,5-Dihydroxytoluene,3,5-二羟基甲苯,地衣酚,5-Methylresorcin,3,5-ToluenediolOrcin,5-Methyl-1,3-benzenediol,Orcin	Others	Others
	orcinol (5-Methylresorcin) 可用于生物染料和蛋白质组学研究。
T8335	Lycobetaine acetate 氧化石蒜碱乙酸盐,Oxylycorine	Others	Others
	Lycobetaine acetate (Oxylycorine) 是一种潜在的抗罗克福提青霉和黑曲霉的生物杀菌剂。
TN1899	Lycoramine	AChE	Neuroscience
	Lycoramine 是一种加兰他敏的二氢衍生物，从Lycoris radiate 中分离得到，是一种乙酰胆碱酯酶抑制剂。
T2S1792	Lycobetaine 石蒜内胺,Ungeremine,石蒜醋胺,石蒜碱内铵盐	Antibacterial	Microbiology/Virology
	Lycobetaine (Ungeremine) 是一种潜在的抗罗克福尔青霉和黑曲霉的生物杀菌剂。它对柱状黄杆菌有很强的抗菌活性。它有效地靶向哺乳动物以及细菌I 型和II 型拓扑异构酶。它显示出强烈的乙酰胆碱酯酶抑制活性（IC(50) 值为 0.35 microM）。它具有抗原生动物活性，在体外试验中对Trypanosoma brucei rhodesiense、T. cruzi 表现出良好的活性。
T2772	S-allyl-L-cysteine S-Allylcysteine,S-烯丙基-L-半胱氨酸	Apoptosis; Others	Apoptosis; Others
	S-allyl-L-cysteine (S-Allylcysteine) 是从大蒜中发现的有机硫化物，对动物具有抗氧化和抗癌特性。
T5751	Tigogenin	Others	Others
	Tigogenin 是甾体皂甙元，普遍用于甾体类药物的合成。它能够阻碍小鼠骨髓基质细胞脂肪细胞分化，促使成骨细胞的分化。
T6S1768	Narcissin 水仙苷,Isorhamnetin 3-Rutinoside,Narcissoside	Antioxidant	oxidation-reduction
	Narcissin (Isorhamnetin 3-Rutinoside) 是一种黄连糖苷，能够清除 ONOO-(IC50:3.5 μM)和 SIN-1 衍生的 ONOO-(IC50:9.6 μM)，具有抗氧化作用。
T2771	Orcinol glucoside Sakakin,苔黑酚葡萄糖苷	Antioxidant	oxidation-reduction
	Orcinol glucoside (Sakakin) 是一种提取自莪术中的活性成分，具有抗抑郁活性。它能诱导 MSC 转化为成骨细胞，并通过 Wnt/β-catenin 信号通路阻断脂肪形成。
TN1576	Diallyl disulfide	IL Receptor; NOS; NF-κB	Immunology/Inflammation; NF-κB
	Diallyl disulfide 能够抑制人角鲨烯单加氧酶，抑制角鲨烯环氧化的 IC50为 400 μM。它也具有抗肿瘤作用，同miR-200b 和miR-22联合使用可增强该作用。
T6S1966	Curculigoside Curculigoside A,仙茅苷	Antioxidant; NF-κB; JAK; STAT	Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; NF-κB; oxidation-reduction; Stem Cells
	Curculigoside (Curculigoside A) 是仙茅中的主要皂苷，具有显著的抗氧化、抗骨质疏松、抗抑郁和神经保护作用。它通过调节JAK/STAT/NF-κB 信号传导途径，具有抗关节炎作用。
T0086	Galanthamine hydrobromide Galantamine hydrobromide,Galanthamine HBr,氢溴酸加兰他敏	AChR; AChE	Neuroscience
	Galanthamine hydrobromide (Galantamine hydrobromide) 是一种长效的中枢活性 AChE 抑制剂，IC50为 410 nM。它是神经元烟碱型 ACh 受体的变构增强剂，IC50值为 0.35 µM，可用于阿尔茨海默症的研究。
T3756	Allitol Allodulcit,蒜糖醇,Allodulcitol,d-allitol	Others	Others
	Allitol (d-allitol) 是一种罕见的可作为甜味剂天然多元醇。它是制备 azasugars 的重要中间体，可用于制备抗癌症、糖尿病及包括艾滋病在内的病毒感染的药物。
T3123	Allicin	ERK; IL Receptor; Others; IκB/IKK; p38 MAPK; TNF; ROS; Caspase; Antifection	Apoptosis; Immunology/Inflammation; MAPK; Microbiology/Virology; NF-κB; Others; Proteases/Proteasome
	Allicin 具有抗氧化、杀菌、抗癌、抗炎活性，对肠上皮细胞具有抑制性免疫调节作用。 Allicin 能显着抑制胰岛素诱导的血管平滑肌细胞的增殖和迁移，这可能与抑制 ERK 信号通路的激活有关。 Allicin 有利于降低高胆固醇血症大鼠的血液胆固醇、甘油三酯水平和收缩压，它可能有益于影响动脉粥样硬化的两个危险因素——高脂血症和高血压。
T3S0860	Gitogenin	UGT	Metabolism
	Gitogenin 是一种从Tribulus longipetalus 整株中分离出来的天然类固醇，是一种 UDP-葡萄糖醛酸转移酶 1A4 (UGT1A4) 和 α-葡萄糖苷酶的选择性抑制剂，其IC50分别为 0.69 µM (使用三氟拉嗪为底物) 和 37.2 μM，对人类主要细胞色素 P450 亚型的活性无抑制作用。
T3S1729	Dihydrolycorine	Others	Others
	Dihydrolycorine 是分离自Lycoris radiate 草药中，是一种真核细胞中蛋白质合成的抑制剂。
T5764	Alliin 蒜氨酸,(S)-3-(Allylsulphinyl)-L-alanine	NF-κB; PPAR	DNA Damage/DNA Repair; Metabolism; NF-κB
	Alliin ((S)-3-(Allylsulphinyl)-L-alanine) 是一种从大蒜中提取的亚砜化合物，具有口服活性，表现出降血糖、抗氧化和抗炎特性。
T2774	Lycorine hydrochloride 石蒜碱,Licorine hydrochloride,Galanthidine hydrochloride,Narcissine hydrochloride,Lycorine chloride,Amarylline hydrochloride,盐酸石蒜碱	Virus Protease; HCV Protease; Antibacterial; Autophagy	Autophagy; Microbiology/Virology; Proteases/Proteasome
	Lycorine hydrochloride (Narcissine hydrochloride) 是黑色素瘤血管生成抑制剂，是一种来自石蒜的主要活性成分，抑制 Hey1B 细胞的有丝分裂增殖，IC50值为 1.2 μM，具有抗肿瘤活性。
T5S1963	Orcinol gentiobioside Anacardoside,苔黑酚龙胆二糖苷	Others	Others
	Orcinol gentiobioside 是一种提取自C. breviscapa根茎块中的天然产物，有抗OP 活性。
T3S0895	Spirostan-3-ol 剑麻皂苷元,Sarsaponin	Others	Others
	Spirostan-3-ol (Sarsaponin) 是 Sarsasapogenin 的立体异构体，是从植物材料中分离出来的类固醇糖苷，具有潜在的通过细胞凋亡的抗肿瘤活性。它可驱赶蜜蜂。
TN2911	3,9-Dihydroeucomin	IL Receptor	Immunology/Inflammation
	(+/-)-3,9-Dihydroeucomin has immunomodulatory effects, it shows inhibitory effects on PBMC proliferation activated by PHA with the IC(50) value of 19.4 microM.
TN3654	Cimilactone A	Others	Others
	Cimilactone A shows significant anticomplement activity (IC(50)= 28.6 microm).
TN4454	Loureiriol	Others	Others
	Loureiriol 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN4454，CAS号为 479195-44-3。
TN6601	Tigogenin acetate
	Tigogenin acetate 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN6601，CAS号为 2530-07-6。
T2S1727	Lycorenine	Antifection	Microbiology/Virology
	Lycorenine may produce a decrease in blood pressure as the result of alpha-adrenergic blockade in conjunction with the reduction of the spontaneous sympathetic nerve activity, and produce bradycardia by modifying vagal activity. The development of tachyph
TN6575	Pilosidine
	Pilosidine has vasoconstrictor activity, it showed facilitating effect on adrenaline evoked contractions in rabbit aorta isolated preparations.
T10025	1-PeCSO S-1-Propenyl-L-cysteine sulfoxide	Others	Others
	1-PeCSO is isolated from onion or garlic bulbs. It acts as a key compound in garlic greening and reacts with lachrymatory factor synthase.
TN4680	Nyasicol 1,2-acetonide	Others	Others
	Nyasicol 1,2-acetonide 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN4680，CAS号为 1432057-64-1。
TN4682	Nyasicoside	Others	Others
	Nyasicoside may have promising and beneficial thrombolytic activity.
TN1270	LPRP-Et-97543 (3R)-5,7-Dihydroxy-6-methyl-3-(4'-hydroxybenzyl)chroman-4-one	Others	Others
	(3R)-5,7-Dihydroxy-6-methyl-3-(4'-hydroxybenzyl)chroman-4-one is a natural product
TN4876	Quercetin 3,4'-diglucoside	Others	Others
	Quercetin 3,4'-diglucoside possesses antioxidant activities.
TN1536	Curculigoside B	Others	Others
	Curculigoside B shows antioxidative and antiosteoporotic activities, it can decrease area of bone resorption pit, osteoclastic formation and TRAP activity.

天然产物

Cat.No: T3324

Synonym: Galanthidine,Narcissine,石蒜碱,Amarylline,Belamarine,Licorine,番石榴碱

Target: Apoptosis, Virus Protease, Antibacterial, AChR, Fatty Acid Synthase

Curculigoside C

Cat.No: TN3732

Target: Others

Cat.No: T11534

Target: Others

5-Hydroxy-3-(4-hydroxybenzyl)-7-methoxychroman-4-one

Cat.No: TN3072

Synonym: 4H-1-Benzopyran-4-one,2,3-dihydro-5-hydroxy-3-[(4-hydroxyphenyl)methyl]-7-methoxy-

Target: Others

Haemanthamine hydrochloride

Cat.No: T73813

Target: Others

2,6-Dimethoxybenzoic acid

Cat.No: T3758

Target: Others, Endogenous Metabolite, Antifungal

Cat.No: T4S1725

Synonym: Galantamine,加兰他敏

Target: Apoptosis, AChE

Cat.No: T3748

Synonym: 5-Methylresorcinol,苔黑素、苔黑酚、地衣酚,3,5-Dihydroxytoluene,3,5-二羟基甲苯,地衣酚,5-Methylresorcin,3,5-ToluenediolOrcin,5-Methyl-1,3-benzenediol,Orcin

Target: Others

Lycobetaine acetate

Cat.No: T8335

Synonym: 氧化石蒜碱乙酸盐,Oxylycorine

Target: Others

Cat.No: TN1899

Target: AChE

Cat.No: T2S1792

Synonym: 石蒜内胺,Ungeremine,石蒜醋胺,石蒜碱内铵盐

Target: Antibacterial

S-allyl-L-cysteine

Cat.No: T2772

Synonym: S-Allylcysteine,S-烯丙基-L-半胱氨酸

Target: Apoptosis, Others

Cat.No: T5751

Target: Others

Cat.No: T6S1768

Synonym: 水仙苷,Isorhamnetin 3-Rutinoside,Narcissoside

Target: Antioxidant

Orcinol glucoside

Cat.No: T2771

Synonym: Sakakin,苔黑酚葡萄糖苷

Target: Antioxidant

Diallyl disulfide

Cat.No: TN1576

Target: IL Receptor, NOS, NF-κB

Cat.No: T6S1966

Synonym: Curculigoside A,仙茅苷

Target: Antioxidant, NF-κB, JAK, STAT

Galanthamine hydrobromide

Cat.No: T0086

Synonym: Galantamine hydrobromide,Galanthamine HBr,氢溴酸加兰他敏

Target: AChR, AChE

Cat.No: T3756

Synonym: Allodulcit,蒜糖醇,Allodulcitol,d-allitol

Target: Others

Cat.No: T3123

Target: ERK, IL Receptor, Others, IκB/IKK, p38 MAPK, TNF, ROS, Caspase, Antifection

Cat.No: T3S0860

Target: UGT

Dihydrolycorine

Cat.No: T3S1729

Target: Others

Cat.No: T5764

Synonym: 蒜氨酸,(S)-3-(Allylsulphinyl)-L-alanine

Target: NF-κB, PPAR

Lycorine hydrochloride

Cat.No: T2774

Synonym: 石蒜碱,Licorine hydrochloride,Galanthidine hydrochloride,Narcissine hydrochloride,Lycorine chloride,Amarylline hydrochloride,盐酸石蒜碱

Target: Virus Protease, HCV Protease, Antibacterial, Autophagy

Orcinol gentiobioside

Cat.No: T5S1963

Synonym: Anacardoside,苔黑酚龙胆二糖苷

Target: Others

Cat.No: T3S0895

Synonym: 剑麻皂苷元,Sarsaponin

Target: Others

3,9-Dihydroeucomin

Cat.No: TN2911

Target: IL Receptor

Cat.No: TN3654

Target: Others

Cat.No: TN4454

Target: Others

Tigogenin acetate

Cat.No: TN6601

Cat.No: T2S1727

Target: Antifection

Cat.No: TN6575

Cat.No: T10025

Synonym: S-1-Propenyl-L-cysteine sulfoxide

Target: Others

Nyasicol 1,2-acetonide

Cat.No: TN4680

Target: Others

Cat.No: TN4682

Target: Others

Cat.No: TN1270

Synonym: (3R)-5,7-Dihydroxy-6-methyl-3-(4'-hydroxybenzyl)chroman-4-one

Target: Others

Quercetin 3,4'-diglucoside

Cat.No: TN4876

Target: Others

Curculigoside B

Cat.No: TN1536

Target: Others

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