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Search Results for " ahr "

Targets Recommended: AhR Aryl Hydrocarbon Receptor

100

抑制剂 & 化合物

15

天然产物

2

重组蛋白

2

同位素标记化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T10269	AHR antagonist 2	Aryl Hydrocarbon Receptor	Immunology/Inflammation
	AHR antagonist 2 是芳基烃受体的拮抗剂。人 AHR 和小鼠 AHR 的 IC50 分别为 0.885 和 2.03 nM。
T39762	AHR antagonist 5 free base	Aryl Hydrocarbon Receptor	Immunology/Inflammation
	AHR antagonist 5 free base 是一种具有口服活性的 AHR 拮抗剂，在人和啮齿动物细胞系中的 IC50 约为 35-150 nM。
T5622	BAY-218 AHR antagonist 1	AhR; Aryl Hydrocarbon Receptor	Immunology/Inflammation; Metabolism
	BAY-218 (AHR antagonist 1) 是一种芳基烃受体(AHR)拮抗剂，在人细胞系中的IC50值为 39.9 nM。
T30984	Cloroperone hydrochloride AHR 6134,AHR-6134,AHR6134	Others	Others
	Cloroperone hydrochloride (AHR-6134) 具有抗焦虑活性，可用于研究神经系统疾病。
T23683	AHR-5333 AHR 5333,AHR5333	Others	Others
	AHR-5333 an antiallergy agent.
T15302	Fluzinamide AHR-8559	Others	Others
	Fluzinamide（AHR-8559）对点燃性杏仁核癫痫发作有抗惊厥作用。
T6424	Bromfenac Sodium AHR 10282B,Bronuck,AHR 10282R,溴芬酸钠	COX	Immunology/Inflammation; Neuroscience
	Bromfenac Sodium (AHR 10282R) 是可口服的COX 抑制剂，抑制COX-1和COX-2的IC50值分别为 5.56 和 7.45 nM。它是溴化非甾体类抗炎药，通常用于白内障的术后炎症和疼痛以及假晶状体囊状黄斑水肿的研究。
T29751	AHR-2244 AHR 2244,AHR2244	Others	Others
	AHR-2244 is a psychotherapeutic agent.
T23679	AHR-13268D AHR 13268D,AHR13268D	Others	Others
	AHR-13268D is a new agent of antiallergic/antihistaminic.
T23681	AHR-15010 AHR 15010	Others	Others
	AHR-15010 is a novel anti-arthritic agent.
T29752	AHR-2666 AHR 2666	Others	Others
	AHR-2666 is a skeletal muscle relaxant.
T29746	AHR 376 AHR376,AHR-376	Others	Others
	AHR 376 is a biochemical.
T29747	AHR-0914 AHR0914,AHR 0914	Others	Others
	AHR-0914 is a biochemical.
T23677	AHR-10718 AHR10718,AHR 10718	Others	Others
	AHR-10718 has an antiarrhythmic effect.
T29750	AHR-1900 hydrochloride AHR-1900 HCl	Others	Others
	AHR-1900 hydrochloride is a butyrophenone derivative used in the treatment of schizophrenia.
T23682	AHR-16303B oxalate AHR 16303B oxalate	Others	Others
	AHR-16303B oxalate is a novel antagonist of 5-HT2 receptors.
T29750L	AHR-1900 free base AHR-1900,	Others	Others
	AHR-1900 free base is a butyrophenone derivative which may be used in the treatment of schizophrenia.
T1280	Nepafenac AL 6515,AHR 9434,奈帕芬胺	COX	Immunology/Inflammation; Neuroscience
	Nepafenac (AHR 9434) 是一种非甾体抗炎药，可抑制COX-2，是Amfenac 的原药。
T29748	AHR-12234	Others	Others
	AHR-12234 affects cardiac action potentials.
T29755	AHR-5904	Others	Others
	AHR-5904 is a biochemical.
T24661	Pridefine AHR-1118 free base,Pridefina	5-HT Receptor	GPCR/G Protein; Neuroscience
	Pridefine (Pridefina) 是一种吡咯烷衍生物，是儿茶酚胺和血清素的再摄取阻断剂，具有抗抑郁活性。
T23684	AHR-6293	Others	Others
	AHR-6293 is used to distinguishing the effect of anti-platelet aggregating drug properties and the effect of anti-inflammatory properties.
T23676	AHR-10037	Others	Others
	AHR-10037是一种非甾体抗炎药，具有镇痛和解热特性以及高治疗指数，低胃毒性，它在抑制急性（伊文思蓝卡拉胶胸腔积液）和慢性（佐剂诱导的关节炎）炎症方面与吲哚美辛相当。研究表明，它在体内转化为环氧合酶抑制剂的前药。
T23680	AHR-14310C	Others	Others
	AHR-14310C is a long-acting and nonsedating H1-antihistamine.
T1409	Methocarbamol Lumirelax,美索巴莫,Metocarbamol,AHR 85,Robaxin	Sodium Channel; Carbonic Anhydrase	Membrane transporter/Ion channel; Metabolism
	Methocarbamol (AHR 85) 是口服有效的中枢肌肉松弛剂，可阻断肌肉Nav1.4通道，阻断作用具有可逆性。Methocarbamol 具有用于肌肉痉挛和疼痛综合症研究的潜力。
T29749	AHR-16329 AHR16329	Others	Others
	AHR-16329 can be used in ocular pharmacology.
T23678	AHR-11797	Others	Others
	AHR-11797 is a novel benzodiazepine antagonist.
T71053	AHR-5333 mandelate	Others	Others
	AHR-5333 mandelate is an anti-allergy compound which has been shown to protect against antigen-induced anaphylactic collapse and ascaris antigen-induced skin hypersensitivity. AHR-5333 mandelate has also been shown to inhibit 5-HETE, LTB4 and LTC4 synthesis.
T29754	AHR-5859	Others	Others
	AHR-5859 is a biochemical.
T23685	AHR-9294	Others	Others
	AHR-9294 is a novel inhibitor of H, K-ATPase. It also antagonizes gastric HCl secretion in vivo.
T29753	AHR-5360 AHR5360	Others	Others
	AHR-5360 is a biochemical.
T29754L	AHR-5859 fumarate	Others	Others
	AHR-5859 fumarate is a biochemical.
T10273	AhR modulator-1	Others	Others
	AhR modulator-1 is a selective and orally active aryl hydrocarbon receptor (AhR) modulator. It inhibits metastasis, in part, by inhibiting prostatic VEGF production prior to tumor formation. It also possesses anti-estrogenic properties in rat uterus.
T10271	AHR antagonist 4	Others	Others
	AHR antagonist 4 is a potent aryl hydrocarbon receptor (AHR) antagonist(example 293; IC50: 82.2 nM).It has anti-cancer effects.
T20986	AHR agonist 3	Others	Others
	AHR agonist 3 is an agent with therapeutic activity.
T10272	AHR antagonist 5	Others	Others
	AHR antagonist 5 is a potent and orally active aryl hydrocarbon receptor (AHR) antagonist(example 39; IC50 < 0.5 μΜ). It significantly inhibits tumor growth combined with checkpoint inhibitor anti-PD-1.
T71590	AHR-5645B fumarate	Others	Others
	AHR-5645B fumarate is a substituted benzamide that has been shown to inhibit 3H-spiperone binding to bovine anterior pituitary membranes.
T17364	AhR Ligand-Linker Conjugates 1 E3 Ligase Ligand-Linker Conjugates 57	Others	Others
	AhR Ligand-Linker Conjugates 1, also known as E3 Ligase Ligand-Linker Conjugates 57, is a chemical compound that combines an IAP ligand for the E3 ubiquitin ligase with a SNIPER linker. It is specifically designed to be used in the development of SNIPER[1].
T23686	AHR-activator-1023 Branching Morphogenesis Modulator 1023,Cpd 1023,Compound 1023,BMM 1023	Others	Others
	AHR-activator-1023 is the aryl hydrocarbon receptor activator. It is also a specific FGF2-induced branching morphogenesis modulator.
T16778	Rocastine AHR-11325	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Rocastine（AHR-11325）是一种具有选择性和有效性的非镇静性 H1 受体拮抗剂。
T21352	Salmefamol AHR-3929,AHR3929,AHR 3929	Others	Others
	Salmefamol is a beta-adrenergic agonist. It may also be used as a bronchodilator.
T31586	Duoperone fumarate AHR6646,AHR-6646,AHR 6646	Others	Others
	Duoperone fumarate is a biochemical.
T31214	Dazopride fumarate AHR-5531C	Others	Others
	Dazopride fumarate is a peristaltic used to enhance gastric emptying and block emesis.
T84540	AHR antagonist 7	Others	Others
	AHR antagonist 7 (CAY10464; 100 nM) 在HepG2细胞中可抑制CYP1A1 mRNA的表达，并对Benzo[a]pyrene抑制载脂蛋白A-I (apo A-I)基因表达的作用产生逆转效应。
T79436	AHR agonist 4	Aryl Hydrocarbon Receptor	Immunology/Inflammation
	AHR agonist 4 (compound 24e) 是针对芳烃受体AHR的激动剂，关联Th17/22与Treg细胞的免疫调节作用。作为治疗银屑病的潜在先导化合物，它能够缓解由咪喹莫特 (IMQ) 诱发的银屑病样皮肤病变。
T20197	Amfenac sodium AHR5850,AHR 5850	Others	Others
	Amfenac is a nonsteroidal anti-inflammatory drug. Amfenac also has acetic acid moiety.
T61244	AhR agonist 2	Others	Others
	AhR agonist 2 (Compound 12a) is a highly potent agonist of the aryl hydrocarbon receptor (AhR), exhibiting an EC50 value of 0.03 nM. This compound rapidly induces nuclear enrichment of AhR and initiates transcription of downstream genes, thereby promoting skin barrier repair. AhR agonist 2 shows promising potential for psoriasis research [1].
T10963	Dazopride 达佐必利,AHR-5531	Others	Others
	Dazopride is an antiemetic agent.
T1610	Metaxalone Skelaxin,Methaxalonum,美他沙酮,Zorane,NSC170959,AHR438	Others	Others
	Metaxalone (Methaxalonum) 具有肌肉松弛作用。
T26710	Azapropazone DuP-141,NSC-102824,AHR-3018,AHR 3018,MI-85	Others	Others
	Azapropazone is anti-inflammatory agent. Azapropazone has uricosuric properties used to treat rheumatoid arthritis and ankylosing spondylitis. Azapropazone lowered plasma uric acid but exerted only a modest and variable uricosuric effect without altering

化合物

AHR antagonist 2

Cat.No: T10269

Target: Aryl Hydrocarbon Receptor

AHR antagonist 5 free base

Cat.No: T39762

Target: Aryl Hydrocarbon Receptor

Cat.No: T5622

Synonym: AHR antagonist 1

Target: AhR, Aryl Hydrocarbon Receptor

Cloroperone hydrochloride

Cat.No: T30984

Synonym: AHR 6134,AHR-6134,AHR6134

Target: Others

Cat.No: T23683

Synonym: AHR 5333,AHR5333

Target: Others

Cat.No: T15302

Synonym: AHR-8559

Target: Others

Bromfenac Sodium

Cat.No: T6424

Synonym: AHR 10282B,Bronuck,AHR 10282R,溴芬酸钠

Target: COX

Cat.No: T29751

Synonym: AHR 2244,AHR2244

Target: Others

Cat.No: T23679

Synonym: AHR 13268D,AHR13268D

Target: Others

Cat.No: T23681

Synonym: AHR 15010

Target: Others

Cat.No: T29752

Synonym: AHR 2666

Target: Others

Cat.No: T29746

Synonym: AHR376,AHR-376

Target: Others

Cat.No: T29747

Synonym: AHR0914,AHR 0914

Target: Others

Cat.No: T23677

Synonym: AHR10718,AHR 10718

Target: Others

AHR-1900 hydrochloride

Cat.No: T29750

Synonym: AHR-1900 HCl

Target: Others

AHR-16303B oxalate

Cat.No: T23682

Synonym: AHR 16303B oxalate

Target: Others

AHR-1900 free base

Cat.No: T29750L

Synonym: AHR-1900,

Target: Others

Cat.No: T1280

Synonym: AL 6515,AHR 9434,奈帕芬胺

Target: COX

Cat.No: T29748

Target: Others

Cat.No: T29755

Target: Others

Cat.No: T24661

Synonym: AHR-1118 free base,Pridefina

Target: 5-HT Receptor

Cat.No: T23684

Target: Others

Cat.No: T23676

Target: Others

Cat.No: T23680

Target: Others

Cat.No: T1409

Synonym: Lumirelax,美索巴莫,Metocarbamol,AHR 85,Robaxin

Target: Sodium Channel, Carbonic Anhydrase

Cat.No: T29749

Synonym: AHR16329

Target: Others

Cat.No: T23678

Target: Others

AHR-5333 mandelate

Cat.No: T71053

Target: Others

Cat.No: T29754

Target: Others

Cat.No: T23685

Target: Others

Cat.No: T29753

Synonym: AHR5360

Target: Others

AHR-5859 fumarate

Cat.No: T29754L

Target: Others

AhR modulator-1

Cat.No: T10273

Target: Others

AHR antagonist 4

Cat.No: T10271

Target: Others

AHR agonist 3

Cat.No: T20986

Target: Others

AHR antagonist 5

Cat.No: T10272

Target: Others

AHR-5645B fumarate

Cat.No: T71590

Target: Others

AhR Ligand-Linker Conjugates 1

Cat.No: T17364

Synonym: E3 Ligase Ligand-Linker Conjugates 57

Target: Others

AHR-activator-1023

Cat.No: T23686

Synonym: Branching Morphogenesis Modulator 1023,Cpd 1023,Compound 1023,BMM 1023

Target: Others

Cat.No: T16778

Synonym: AHR-11325

Target: Histamine Receptor

Cat.No: T21352

Synonym: AHR-3929,AHR3929,AHR 3929

Target: Others

Duoperone fumarate

Cat.No: T31586

Synonym: AHR6646,AHR-6646,AHR 6646

Target: Others

Dazopride fumarate

Cat.No: T31214

Synonym: AHR-5531C

Target: Others

AHR antagonist 7

Cat.No: T84540

Target: Others

AHR agonist 4

Cat.No: T79436

Target: Aryl Hydrocarbon Receptor

Cat.No: T20197

Synonym: AHR5850,AHR 5850

Target: Others

AhR agonist 2

Cat.No: T61244

Target: Others

Cat.No: T10963

Synonym: 达佐必利,AHR-5531

Target: Others

Cat.No: T1610

Synonym: Skelaxin,Methaxalonum,美他沙酮,Zorane,NSC170959,AHR438

Target: Others

Cat.No: T26710

Synonym: DuP-141,NSC-102824,AHR-3018,AHR 3018,MI-85

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
TN1451	Brevifolincarboxylic acid	AhR; Aryl Hydrocarbon Receptor; Glucosidase	Immunology/Inflammation; Metabolism
	Brevifolincarboxylic acid 是从头状蓼中分离得到的一种天然产物，抑制芳烃受体(AhR)。它是一种 α-葡萄糖苷酶抑制剂，IC50 为 323.46 μM。
T6795	Carbidopa 卡比多巴,(S)-(-)-Carbidopa,Lodosyn	Decarboxylase; Aryl Hydrocarbon Receptor	Immunology/Inflammation; Metabolism; Others
	Carbidopa (Lodosyn) 是一种选择性芳香烃受体(AhR)调节剂，是外周型脱羧酶抑制剂，抑制胰腺癌细胞和肿瘤生长，可用于帕金森病的研究。
T4928	L-Kynurenine L-犬尿氨酸,(S)-Kynurenine	AhR; Aryl Hydrocarbon Receptor; Endogenous Metabolite	Immunology/Inflammation; Metabolism
	L-Kynurenine ((S)-Kynurenine) 是L-色氨酸的代谢物，是芳香烃受体激动剂，可抑制同种异体 T 细胞增殖并增加恶性 U87 神经胶质瘤细胞侵入胶原基质。
T0878	Diosmin Venosmine,Diosmil,Barosmin,地奥司明,地奥司明（7-芸香糖甙）	Aryl Hydrocarbon Receptor; Norepinephrine	Immunology/Inflammation; Neuroscience
	Diosmin (Venosmine) 是在各种柑橘类水果中发现的类黄酮，也是芳烃受体激动剂，有增强血管壁的作用。
T4644	Tapinarof GSK2894512,Benvitimod,苯烯莫德,WBI 1001	AhR; Aryl Hydrocarbon Receptor	Immunology/Inflammation; Metabolism
	Tapinarof (Benvitimod) 是一种从发光杆菌中提取的天然产物，可消除炎症。它是芳烃受体 (AhR) 激动剂，EC50为 13 nM。
TN2883	3',4'-Dimethoxyflavone	Others; PARP	Chromatin/Epigenetic; DNA Damage/DNA Repair; Others
	3',4'-Dimethoxyflavone 是类黄酮化合物的参考标准，类黄酮化合物具有多种药用活性。
T4939	Indole-3-pyruvic acid 3-(3-吲哚基)-2-氧代丙酸,3-(3-Indolyl)-2-oxopropanoic acid	Others	Others
	Indole-3-pyruvic acid (3-(3-Indolyl)-2-oxopropanoic acid) 是一种参与Indole-3-acetic acid 生物合成的化合物，Indole-3-acetic acid 是一种植物激素，在调节生长和对环境变化的反应中起重要作用。
T5281	Skatole 粪臭素,Scatole,3-Methylindole,3-Methylindole,3-甲基吲哚,3-Methyl-1H-indole,beta-Methylindole	AhR; p38 MAPK; Aryl Hydrocarbon Receptor; Endogenous Metabolite; Antibacterial; Autophagy; Antifungal	Autophagy; Immunology/Inflammation; MAPK; Metabolism; Microbiology/Virology
	Skatole (3-Methyl-1H-indole) 是由肠道菌群产生的，通过激活芳基烃受体和 p38调节肠上皮细胞功能。
T2947	Indole-3-carbinol 吲哚-3-甲醇,I3C,3-Indolemethanol,3-吲哚甲醇,Indole-3-Methanol	E1/E2/E3 Enzyme; NF-κB; Aryl Hydrocarbon Receptor; Endogenous Metabolite; p53	Apoptosis; Immunology/Inflammation; Metabolism; NF-κB; Ubiquitination
	Indole-3-carbinol (I3C) 是樟子松中的一种天然产物，是可口服的硫代葡萄糖苷葡糖苷酶裂解产物。它是芳烃受体 (AhR) 的激动剂，可抑制 NF-κB 和 IκBα 激酶活化。
T10938	D-Kynurenine D-尿嘧啶,(R)-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid,ZINC901103	GPR; AhR; Endogenous Metabolite	Endocrinology/Hormones; GPCR/G Protein; Immunology/Inflammation; Metabolism
	D-Kynurenine (ZINC901103) 是 D-色氨酸的代谢物和 GPR109B 的激动剂。 D-Kynurenine 激活 AhR 并促进上皮细胞向间充质的转化。 D-Kynurenine 在 D-氨基酸氧化酶的荧光分析中用作底物。
T4938	Potassium 1H-indol-3-yl sulfate 硫酸吲哚钾盐,Indoxyl sulfate potassium salt,Potassium 3-indoxyl sulfate	AhR; Endogenous Metabolite	Immunology/Inflammation; Metabolism
	Potassium 1H-indol-3-yl sulfate (Potassium 3-indoxyl sulfate) 是人芳烃受体(AhR)的激动剂。芳烃受体(AhR)最近被发现是免疫炎症条件的病理生理调节剂，Potassium 1H-indol-3-yl sulfate 已被证明是AhR的配体。Potassium 1H-indol-3-yl sulfate 也是膳食蛋白质中色氨酸的代谢物。色氨酸被肠道细菌代谢为吲哚，吲哚被吸收到血液中，然后在肝脏中进一步代谢为硫酸吲哚，通常通过尿液排出体外。在肾功能受损的慢性肾病患者中，Potassium 1H-indol-3-yl sulfate 可作为尿毒症毒素在血清中积累，诱导氧化应激并加速疾病进展。250 μM Potassium 1H-indol-3-yl sulfate 可诱导NF-Κb活化，促进大鼠近端小管细胞TGF-β1和Smad3的表达，与促纤维化活性相关。
TN1222	26-Deoxyactein 27-Deoxyactein,脱氧升麻烃,23-epi-26-Deoxyactein,27-脱氧升麻亭	NOS; CDK; NO Synthase	Cell Cycle/Checkpoint; Immunology/Inflammation
	23-epi-26-Deoxyactein (27-Deoxyactein) 是一种黑升麻中的主要成分，能够阻止 TCDD 诱导的成骨细胞的损伤。它对 AhR，CYP1A1 和 ERK 的水平升高具有抑制作用。
T72901	Indolokine A5	Others	Others
	Indolokine A5, L-半胱氨酸的分解代谢物, 是一种有效的AhR 激动剂。
T73402	Flavipin	Others	Others
	Flavipin 是一种芳香烃受体(Ahr)激动剂，可诱导小鼠 CD4+T 细胞和 CD11b+巨噬细胞表达 Ahr 下游基因。Flavipin 抑制 Arid5a 在 Il23a3'UTR 上的稳定功能，这是一种新发现的靶 mRNA。Flavipin 具有清除 DPPH 自由基的能力，IC50值为7.2 μM，对α-葡萄糖苷酶具有较强的抑制作用，IC50值为 33.8 μM。
T75433	Norisoboldine hydrochloride	Others	Others
	Norisoboldine hydrochloride是一种口服活性天然芳基烃受体(AhR)激动剂，作为林参中的主要异喹啉类生物碱，适用于类风湿性关节炎和溃疡性结肠炎的研究。

天然产物

Brevifolincarboxylic acid

Cat.No: TN1451

Target: AhR, Aryl Hydrocarbon Receptor, Glucosidase

Cat.No: T6795

Synonym: 卡比多巴,(S)-(-)-Carbidopa,Lodosyn

Target: Decarboxylase, Aryl Hydrocarbon Receptor

Cat.No: T4928

Synonym: L-犬尿氨酸,(S)-Kynurenine

Target: AhR, Aryl Hydrocarbon Receptor, Endogenous Metabolite

Cat.No: T0878

Synonym: Venosmine,Diosmil,Barosmin,地奥司明,地奥司明（7-芸香糖甙）

Target: Aryl Hydrocarbon Receptor, Norepinephrine

Cat.No: T4644

Synonym: GSK2894512,Benvitimod,苯烯莫德,WBI 1001

Target: AhR, Aryl Hydrocarbon Receptor

3',4'-Dimethoxyflavone

Cat.No: TN2883

Target: Others, PARP

Indole-3-pyruvic acid

Cat.No: T4939

Synonym: 3-(3-吲哚基)-2-氧代丙酸,3-(3-Indolyl)-2-oxopropanoic acid

Target: Others

Cat.No: T5281

Synonym: 粪臭素,Scatole,3-Methylindole,3-Methylindole,3-甲基吲哚,3-Methyl-1H-indole,beta-Methylindole

Target: AhR, p38 MAPK, Aryl Hydrocarbon Receptor, Endogenous Metabolite, Antibacterial, Autophagy, Antifungal

Indole-3-carbinol

Cat.No: T2947

Synonym: 吲哚-3-甲醇,I3C,3-Indolemethanol,3-吲哚甲醇,Indole-3-Methanol

Target: E1/E2/E3 Enzyme, NF-κB, Aryl Hydrocarbon Receptor, Endogenous Metabolite, p53

Cat.No: T10938

Synonym: D-尿嘧啶,(R)-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid,ZINC901103

Target: GPR, AhR, Endogenous Metabolite

Potassium 1H-indol-3-yl sulfate

Cat.No: T4938

Synonym: 硫酸吲哚钾盐,Indoxyl sulfate potassium salt,Potassium 3-indoxyl sulfate

Target: AhR, Endogenous Metabolite

Cat.No: TN1222

Synonym: 27-Deoxyactein,脱氧升麻烃,23-epi-26-Deoxyactein,27-脱氧升麻亭

Target: NOS, CDK, NO Synthase

Cat.No: T72901

Target: Others

Cat.No: T73402

Target: Others

Norisoboldine hydrochloride

Cat.No: T75433

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-00958	AHR Protein, Human, Recombinant (His) Aryl hydrocarbon receptor,Class E basic helix-loop-helix pro...	Human	E. coli
	AHR Protein, Human, Recombinant (His) is expressed in E. coli.
TMPJ-00423	TIM-1/KIM-1/HAVCR1 Protein, Mouse, Recombinant (His) Hepatitis A virus cellular receptor 1 homolog,HAVcr-1,T cell...	Mouse	HEK293 Cells
	TIM-1/KIM-1/HAVCR belongs to the immunoglobulin superfamily that cosisits 305 amino acid (aa). It is expressed by stimulated T-cells. TIM-1/KIM-1/HAVCR may play a role in T-helper cell development and the regulation of asthma and allergic diseases. Receptor for TIMD4. And may have a role in kidney injury and repair. Belongs to the T-cell and airway phenotype regulator (Tapr) locus, a single chromosomal region that confers reduced T-helper type 2 responsiveness and protects against airway hypera...

重组蛋白

AHR Protein, Human, Recombinant (His)

Cat.No: TMPH-00958

Species: Human

Expression System: E. coli

TIM-1/KIM-1/HAVCR1 Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-00423

Species: Mouse

Expression System: HEK293 Cells

Cat. No.	Product Name	Target	Signaling Pathways
T12208	Nepafenac-d5 奈帕芬胺 D5,AHR-9434 D5,AL-6515 D5	Others	Others
	Nepafenac D5 is the deuterium labeled Nepafenac, which is a selective inhibitor of COX-2 .
T70313	Indoxyl Sulfate-d5 potassium salt
	Indoxyl sulfate-d5 is intended for use as an internal standard for the quantification of indoxyl sulfate by GC- or LC-MS. Indoxyl sulfate is a uremic toxin and a metabolite of tryptophan. It is formed via sulfation of indole, an intermediate generated from tryptophan by intestinal bacteria, by the sulfotransferase (SULT) isoform 1A1 variant 2 (SULT1A12) in the liver. Indoxyl sulfate activates the aryl hydrocarbon receptor (AhR*) in HepG2 40/6 hepatoma cells (EC50 = 12.1 nM in a reporter assay). ...

同位素标记化合物

Cat.No: T12208

Synonym: 奈帕芬胺 D5,AHR-9434 D5,AL-6515 D5

Target: Others

Indoxyl Sulfate-d5 potassium salt

Cat.No: T70313

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