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Search Results for " adp "

Targets Recommended: NADPH-oxidase NADPH Others

227

抑制剂 & 化合物

48

天然产物

3

化合物库

64

重组蛋白

2

同位素标记化合物

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Cat. No.	Product Name
L1120	AMPK靶向分子库		80 compounds
	80 个靶向AMPK 的分子集合，可用于高通量和高内涵筛选；
L3500	组蛋白修饰化合物库		469 compounds
	469 个组蛋白修饰相关的小分子化合物的特有集合，用于高通量、高内涵筛选；
L8300	染色质修饰分子库		250 compounds
	250 种染色质化学修饰相关的生物活性小分子化合物的特有集合，用于高通量、高内涵筛选；

化合物库

AMPK靶向分子库

Cat.No: L1120

Compounds: 80

组蛋白修饰化合物库

Cat.No: L3500

Compounds: 469

染色质修饰分子库

Cat.No: L8300

Compounds: 250

Cat. No.	Product Name	Target	Signaling Pathways
T29669	ADP-Ribosylarginine alpha-ADP-ribosylarginine	Others	Others
	ADP-Ribosylarginine can regulate cell proliferation and tumorigenesis.
T29668	ADP-2341 ADP 2341	Others	Others
	ADP-2341 is a soluble analog of FiVe1.
T37118	ADP-Glucose (sodium salt) ADPG,Adenosine-5'-diphosphoglucose,ADP-Glucose (sodium salt)	Others	Others
	ADP-Glucose (ADPG) is an immediate precursor used in the biosynthesis, by glucose addition, of storage polysaccharides in plants, green algae, and cyanobacteria, as well as structural polysaccharides in certain bacteria.[1],[2] It is used by amylose synthases or starch synthases in plastids in the production of amylose, amylopectins, starch, and other polysaccharides. ADPG is normally generated within plastids, although it can be biosynthesized in the cytoplasm of certain grasses and imported in...
T37475	Cyclic ADP-Ribose (ammonium salt) cADP-Ribose,cADPR,Cyclic ADP-Ribose (ammonium salt)	Others	Others
	Cyclic ADP-ribose (cADP-ribose) is an endogenous metabolite of NAD+ that mobilizes the release of stored Ca2+ in the endoplasmic reticulum via ryanodine receptors in various cell types.[1],[2],[3],[4],[5] This second messenger is generated via the cADP-ribose synthases CD38 and CD157.[6],[5],[7] cADP-Ribose may also trigger the cell surface Ca2+ influx channel TRPM2 in a temperature-dependent manner.[8] In vitro, cADP-ribose modulates Ca2+ signaling in rat and mouse cardiomyocytes treated with i...
T10247	Adenosine 5'-diphosphoribose sodium Adenosine 5'-diphosphoribose sodium,ADP ribose sodium	Endogenous Metabolite; TRP/TRPV Channel; Autophagy	Autophagy; Membrane transporter/Ion channel; Metabolism
	Adenosine 5'-diphosphoribose sodium (ADP ribose sodium) 是一种烟酰胺腺嘌呤核苷酸 (NAD+) 的代谢产物，广泛存在于生物体内。Adenosine 5'-diphosphoribose sodium (ADP ribose sodium) 是一种高效的细胞内 Ca2+ 渗透性阳离子 TRPM2 通道激活剂，还可以诱导自噬 (autophagy)。
T29348	2-Fluoro-ADP	Others	Others
	2-Fluoro-ADP is a bioactive chemical.
T37803	8-bromo-Cyclic ADP-Ribose (sodium salt)	Others	Others
	Cyclic ADP-ribose (cADP-ribose) is a calcium mobilizing nucleotide that is biosynthesized from NAD+ by cADP-ribose synthases, including CD38. cADP-Ribose appears to activate calcium channels in intracellular membranes, which in turn activate ryanodine receptors. 8-bromo-cADP-Ribose is a stable, cell-permeable analog that blocks calcium release evoked by cADP-ribose in sea urchin egg homogenates with an IC50 value of 1.7 μM. It is commonly used to investigate intracellular signaling through cADP-...
T78401	pNP-ADPr disodium ADP-ribose-pNP disodium
	pNP-ADPr 二钠是一种用于检测Poly(ADP-ribose) glycohydrolase (PARG)和ADP-ribosyl hydrolase 3 (ARH3)活性的比色底物。它也适用于poly(ADP-ribose)polymerase (PARP)酶相关研究。
T23581	2-Methylthioadenosine diphosphate trisodium 2 Methylthio ADP,2MeSADP,2-Methylthio-ADP,2 MeS ADP,2-MeS-ADP	Others	Others
	2-MeS-ADP is a purinergic agonist that acts by displaying selectivity for P2Y1, P2Y12, and P2Y13 receptors and inhibiting cAMP accumulation.
T63538	8-Azido-ADP disodium	Others	Others
	8-Azido-ADP (disodium) 是一种线粒体腺嘌呤核苷酸易位的共价结合抑制剂，对ADP 诱导的线粒体呼吸的 4 到 3 正常转变表现出抑制作用。在光依赖反应中，8-Azido-ADP (disodium) 不可逆的抑制腺嘌呤核苷酸交换。
T50098	TIQ-A	PARP	Chromatin/Epigenetic; DNA Damage/DNA Repair
	TIQ-A 是一种 PARP1 抑制剂，通过碱基切除修复途径参与 DNA 单链断裂修复。 PARP1 由 DNA 损伤触发，其过度激活已被认为是许多病理状况的致病因素，包括缺血和再灌注损伤、哮喘相关炎症和动脉粥样硬化形成。
T32764	Linear-benzoadenosine diphosphate Lin-benzo-ADP	Others	Others
	Linear-benzoadenosine diphosphate is a nucleotide analog.
T83785	2-Chloroadenosine-5'-O-diphosphate sodium 2-chloro ADP	Others	Others
	2-Chloroadenosine-5'-O-diphosphate是一种腺苷5'二磷酸（ADP）的衍生物。它在浓度依赖性的方式下，促进了人类富含血小板的血浆中的聚集，并抑制了由前列腺素E2（PGE2）诱导的环磷酸腺苷（cAMP）的产生。2-Chloroadenosine-5'-O-diphosphate引起预收缩的孤立的豚鼠taenia coli条带放松（pD2 = 6.74），降低大鼠的动脉血压。此外，它还抑制了热休克蛋白70（Hsp70）家族成员mortalin的ATP酶活性（人类酶的表观Ki = 45.05 µM）。
T41083	pNP-ADPr pNP-ADPr,ADP-ribose-pNP	Others	Others
	pNP-ADPr is a colorimetric substrate employed in the first continuous activity assays for Poly(ADP-ribose) glycohydrolase (PARG) and ADP-ribosyl hydrolase 3 (ARH3). Its utilization facilitates research on poly(ADP-ribose) polymerase (PARP) enzymes.
T83806	Sp-Adenosine-5'-O-(1-thiodiphosphate) sodium Sp-ADP-α-S	Others	Others
	Sp-Adenosine-5’-O-(1-thiodiphosphate) (Sp-ADP-α-S) 是硫含量核苷酸衍生物ADP-α-S的一种异构体。它是磷酸化酶激酶的抑制剂（Ki = 0.53 µM）。Sp-ADP-α-S能引起人类孤立血小板聚集（EC50 = 20 µM），并能使羧胺胆碱预收缩的豚鼠taenia coli松弛（EC50 = 58.9 µM）。
T83805	Rp-Adenosine-5'-O-(1-thiodiphosphate) sodium Rp-ADP-α-S	Others	Others
	Rp-Adenosine-5'-O-(1-thiodiphosphate)（Rp-ADP-α-S）是ADP-α-S的含硫异构体，是磷酸化酶激酶的抑制剂（Ki = 0.53 µM）。此化合物能诱导分离的人类血小板聚集（EC50 = 20 µM），并能引发经卡巴胆碱预收缩的豚鼠乙状结肠松弛（EC50 = 58.9 µM）。
T22749	DR2313 DR 2313	PARP	Chromatin/Epigenetic; DNA Damage/DNA Repair
	DR2313 是一种选择性，竞争性的和可透过血脑屏障的PARP 抑制剂，对PARP-1和PARP-2的IC50值分别为 0.20 和 0.24 μM。它在体内外均有对缺血性损伤的神经保护作用。
T16761	RK-287107	Others; PARP	Chromatin/Epigenetic; DNA Damage/DNA Repair; Others
	RK-287107 是一种有效且特异性的 tankyrase 抑制剂，可阻断结直肠癌细胞生长，对 tankyrase-1和 tankyrase-2的 IC50分别为 14.3 和 10.6 nM。
T6181	UPF 1069	PARP	Chromatin/Epigenetic; DNA Damage/DNA Repair
	UPF 1069 是一种特异性PARP 抑制剂，对 PARP-1 和 PARP-2 的IC50值分别为 8 和 0.3 μM。
T83813	8-Azidoadenosine-5'-O-diphosphate sodium 8-azido-ADP,Click Tag™ 8-Azidoadenosine-5'-O-diphosphate
	8-Azidoadenosine-5'-O-diphosphate（8-azido-ADP）是ATP前体和嘌呤受体配体ADP的可点击形式。8-azido-ADP的放射性标记形式已被用作各种蛋白质的光亲和标签，包括从牛脑中分离的谷氨酸脱氢酶（GDH）同工酶，以及从兔网织红细胞中分离的真核翻译起始因子2（eIF2）和鸟苷核苷酸交换因子（GEF）。
T2484	AZD-2461	PARP	Chromatin/Epigenetic; DNA Damage/DNA Repair
	AZD-2461 是一种 PARP 抑制剂，可抑制 PARP1、PARP2 和 PARP3 的活性，IC50值分别为 5、2 和 200 nM。
T4022	QS11 QS 11	GTPase	GPCR/G Protein
	QS11 是一种ARFGAP1抑制剂(EC50:1.5 µM)。QS 11 能抑制 ARFGAP 过表达的乳腺癌细胞迁移。QS 11 通过影响蛋白质运输来增强 Wnt/β-catenin 信号。
T6197	PJ34	PARP	Chromatin/Epigenetic; DNA Damage/DNA Repair
	PJ34 是一种PARP1/2的特异性有效抑制剂，IC50分别为 110 nM 和 86 nM。
T6578	ME0328	PARP	Chromatin/Epigenetic; DNA Damage/DNA Repair
	ME0328 是一种有效的选择性 PARP 抑制剂，对 PARP3 的 IC50 为 0.89 μM。
T6768	AZ6102	PARP; Wnt/beta-catenin	Chromatin/Epigenetic; Cytoskeletal Signaling; DNA Damage/DNA Repair; Stem Cells
	AZ6102 是TNKS1和TNKS2双重抑制剂，IC50值分别为 3 和 1 nM，选择性是对 PARP 家族其他蛋白的 100 多倍，对 PARP1、PARP2 和 PARP6 的IC50值分别为 2.0、0.5 和大于 3 μM。
T39785L	TH5427	NUDIX hydrolase	Metabolism
	TH5427 在 NUDT5 活性和 ADP-核糖代谢中有研究的价值。它阻断孕激素依赖性、PAR 衍生的核 ATP 合成以及随后的乳腺癌细胞染色质重塑、基因调控和增殖。NUDT5是乳腺癌细胞激素依赖性基因调控和增殖的变阻器。
T9165	AZD5305	PARP	Chromatin/Epigenetic; DNA Damage/DNA Repair
	AZD5305 是一种强效、选择性和口服活性 PARP 抑制剂，可用于肿瘤异体移植模型研究。
T15639	K-756	PARP; Wnt/beta-catenin	Chromatin/Epigenetic; Cytoskeletal Signaling; DNA Damage/DNA Repair; Stem Cells
	K-756 是一种直接的 tankyrase(TNKS) 选择性抑制剂，对 TNKS1和 TNKS2的 ADP-核糖基化活性有抑制作用，IC50分别为 31 和 36 nM。
T21524	4-amino-1,8-Naphthalimide	PARP	Chromatin/Epigenetic; DNA Damage/DNA Repair
	4-amino-1,8-Naphthalimide 是PARP 抑制剂，可增强癌细胞对 γ 辐射诱导的细胞毒性的敏感度。
T3168	MN-64 MN64	Others; PARP; Wnt/beta-catenin	Chromatin/Epigenetic; Cytoskeletal Signaling; DNA Damage/DNA Repair; Others; Stem Cells
	MN-64 是一种有效的tankyrase 1抑制剂，对TNKS1、TNKS2、ARTD1 和 ARTD2 的IC50值分别为 6、72、19.1 和 39.4 μM。
T6842	G007-LK	PARP; Wnt/beta-catenin	Chromatin/Epigenetic; Cytoskeletal Signaling; DNA Damage/DNA Repair; Stem Cells
	G007-LK 是 TNKS1 和 TNKS2 的选择性抑制剂，IC50 分别为 46 nM 和 25 nM。
T8964	G244-LM	Others; PARP	Chromatin/Epigenetic; DNA Damage/DNA Repair; Others
	G244-LM 是一种特异性有效的tankyrase 1/2抑制剂，可抑制Wnt 信号传导。
T4471	E7449 Stenoparib,UNII-9X5A2QIA7C	Others; PARP	Chromatin/Epigenetic; DNA Damage/DNA Repair; Others
	E7449 (UNII-9X5A2QIA7C) 是一种有效的 PARP1 和 PARP2 抑制剂，也抑制 TNKS1 和 TNKS2，使用 32P-NAD+ 作为底物，对 PARP1、PARP2、TNKS1 和 TNKS2 的 IC50 分别为 2.0、1.0、约 50 和约 50 nM。
T1807	JW 55 JW55	PARP; Wnt/beta-catenin	Chromatin/Epigenetic; Cytoskeletal Signaling; DNA Damage/DNA Repair; Stem Cells
	JW 55 (JW55) 是一种有效且选择性的 β-catenin 信号通路抑制剂，通过抑制 tankyrase 1 和 tankyrase 2 (TNKS1/2) 的 PARP 结构域起作用。
T22264	AZ9482	PARP	Chromatin/Epigenetic; DNA Damage/DNA Repair
	AZ9482 是一种选择性 PARP1/2/6的三重抑制剂，IC50值分别为 1 、1 和640 nM。
T7042	1,5-Isoquinolinediol	PARP	Chromatin/Epigenetic; DNA Damage/DNA Repair
	1,5-Isoquinolinediol 是一种多聚（ADP-核糖）合成酶抑制剂，对PARP1的IC50值为 0.39 µM。它用于研究 PARP1 在 DNA 修复和氧化应激诱导的细胞死亡中的作用。
T3062	WIKI4	PARP; Wnt/beta-catenin	Chromatin/Epigenetic; Cytoskeletal Signaling; DNA Damage/DNA Repair; Stem Cells
	WIKI4 是tankyrase 有效抑制剂，其对TNKS2的IC50值为 26 nM。它有效抑制Wnt/β-catenin 信号传导，其EC50值为 75 nM。它通过抑制TNKS2的酶活性来介导其对Wnt/β-catenin 信号传导的影响。它对 SCLC 细胞具有细胞毒性，其IC50值为 0.02 μM。
T5058	Pamiparib BGB-290	PARP	Chromatin/Epigenetic; DNA Damage/DNA Repair
	Pamiparib (BGB-290) 是一种具有口服活性、强效、高选择性的 PARP 抑制剂，对PARP1和PARP2的IC50值分别为 0.9 nM 和 0.5 nM。它具有强大的 PARP 捕获能力，具有穿透大脑的能力，可用于研究癌症。
T6339	AG14361 AG 14361,AG-14361	PARP	Chromatin/Epigenetic; DNA Damage/DNA Repair
	AG14361 是一种 PARP-1抑制剂，Ki 值小于 5 nM，在通透的 SW620 细胞和完整的 SW620 细胞中，抑制 PARP-1的活性，IC50值分别为 29 和 14 nM。
T5399	GeA-69	PARP	Chromatin/Epigenetic; DNA Damage/DNA Repair
	GeA-69 是一种选择性变构 PARP14 大结构域 2 (MD2) 抑制剂，Kd 值为 2.1 µM。
T4472	NMS-P118	PARP	Chromatin/Epigenetic; DNA Damage/DNA Repair
	NMS-P118是可口服的高选择性PARP-1抑制剂，用于癌症治疗，在HeLa 细胞中的IC50值为0.04 μM。
T9593	Senaparib IMP4297	PARP	Chromatin/Epigenetic; DNA Damage/DNA Repair
	Senaparib (IMP4297) 是一种选择性和口服有效的PARP1/2抑制剂，具有强效的抗肿瘤活性。
T22414	RBN012759	PARP	Chromatin/Epigenetic; DNA Damage/DNA Repair
	RBN012759 是选择性和具有口服活性的 PARP14抑制剂，IC50值小于3 nM，可降低促肿瘤巨噬细胞功能并在肿瘤外植体中引发炎症反应，比对 monoPARPs 的选择性高 300 倍，比对 polyPARPs 的选择性高 1000 倍。
T15588	Iobenguane sulfate MIBG sulfate	Others	Others
	Iobenguane sulfate (MIBG sulfate) 是一种具有抗肿瘤活性的神经递质去甲肾上腺素的类似物。Iobenguane sulfate 是一种高亲和力的霍乱毒素底物，干扰细胞单核(ADP-核糖基化)。放射性碘代 Iobenguane sulfate 可用于肾上腺肿瘤诊断和肿瘤靶向药物的研究。
T9430	Venadaparib NOV140101,IDX-1197	PARP	Chromatin/Epigenetic; DNA Damage/DNA Repair
	Venadaparib (NOV140101) 是一种选择性和具有口服活性的 PARP 抑制剂，对 PARP1和 PARP2的 IC50分别为 1.4 和 1.0 nM。它可防止 DNA 单链断裂 (SSB) 的修复，可研究实体瘤。
T7896	BYK204165 RT-017290	PARP	Chromatin/Epigenetic; DNA Damage/DNA Repair
	BYK204165 (RT-017290) 是一种选择性PARP1抑制剂，对重组人 PARP1的pIC50值为 7.35，pKi 值为7.05。它对鼠 PARP-2的pIC50值为 5.38 ，其对 PARP1 的选择性比对 PARP2 高 100 倍。
T3649	BGP-15 BGP15,BGP-15 2HCl	PARP	Chromatin/Epigenetic; DNA Damage/DNA Repair
	BGP-15 (BGP-15 2HCl) 是一种PARP 抑制剂，IC50和Ki 值分别为 120 和 57 μM，在缺血再灌注损伤后具有保护作用。
T12695	RBN-2397	PARP	Chromatin/Epigenetic; DNA Damage/DNA Repair
	RBN-2397 是一种有效的、选择性的、具有口服活性的跨物种 NAD+ 竞争性 PARP7 抑制剂，IC50 小于 3 nM。它选择性结合 PARP7 ，Kd 为0.001 μM，可恢复干扰素 I 型信号转导，有用于晚期或转移性实体肿瘤的研究潜力。
T9497	Niraparib tosylate monohyrate	PARP	Chromatin/Epigenetic; DNA Damage/DNA Repair
	Niraparib tosylate monohyrate 也称为 MK-4827，是一种聚 (ADP-核糖) 聚合酶 (PARP) 抑制剂，具有潜在的抗肿瘤活性。 MK4827 抑制 PARP 活性，增强 DNA 链断裂的积累，促进基因组不稳定性和细胞凋亡。 PARP 蛋白家族通过碱基切除修复 (BER) 途径检测和修复单链 DNA 断裂。
T1878	XAV-939 XAV939,NVP-XAV939	PARP; Wnt/beta-catenin	Chromatin/Epigenetic; Cytoskeletal Signaling; DNA Damage/DNA Repair; Stem Cells
	XAV-939 (NVP-XAV939) 是一种 Tankyrase (TNKS) 抑制剂，抑制 TNKS1 和 TNKS2 (IC50=11/4 nM)。XAV-939 可以选择性抑制 Wnt/β-catenin 介导的转录。

化合物

ADP-Ribosylarginine

Cat.No: T29669

Synonym: alpha-ADP-ribosylarginine

Target: Others

Cat.No: T29668

Synonym: ADP 2341

Target: Others

ADP-Glucose (sodium salt)

Cat.No: T37118

Synonym: ADPG,Adenosine-5'-diphosphoglucose,ADP-Glucose (sodium salt)

Target: Others

Cyclic ADP-Ribose (ammonium salt)

Cat.No: T37475

Synonym: cADP-Ribose,cADPR,Cyclic ADP-Ribose (ammonium salt)

Target: Others

Adenosine 5'-diphosphoribose sodium

Cat.No: T10247

Synonym: Adenosine 5'-diphosphoribose sodium,ADP ribose sodium

Target: Endogenous Metabolite, TRP/TRPV Channel, Autophagy

Cat.No: T29348

Target: Others

8-bromo-Cyclic ADP-Ribose (sodium salt)

Cat.No: T37803

Target: Others

pNP-ADPr disodium

Cat.No: T78401

Synonym: ADP-ribose-pNP disodium

2-Methylthioadenosine diphosphate trisodium

Cat.No: T23581

Synonym: 2 Methylthio ADP,2MeSADP,2-Methylthio-ADP,2 MeS ADP,2-MeS-ADP

Target: Others

8-Azido-ADP disodium

Cat.No: T63538

Target: Others

Cat.No: T50098

Target: PARP

Linear-benzoadenosine diphosphate

Cat.No: T32764

Synonym: Lin-benzo-ADP

Target: Others

2-Chloroadenosine-5'-O-diphosphate sodium

Cat.No: T83785

Synonym: 2-chloro ADP

Target: Others

Cat.No: T41083

Synonym: pNP-ADPr,ADP-ribose-pNP

Target: Others

Sp-Adenosine-5'-O-(1-thiodiphosphate) sodium

Cat.No: T83806

Synonym: Sp-ADP-α-S

Target: Others

Rp-Adenosine-5'-O-(1-thiodiphosphate) sodium

Cat.No: T83805

Synonym: Rp-ADP-α-S

Target: Others

Cat.No: T22749

Synonym: DR 2313

Target: PARP

Cat.No: T16761

Target: Others, PARP

Cat.No: T6181

Target: PARP

8-Azidoadenosine-5'-O-diphosphate sodium

Cat.No: T83813

Synonym: 8-azido-ADP,Click Tag™ 8-Azidoadenosine-5'-O-diphosphate

Cat.No: T2484

Target: PARP

Cat.No: T4022

Synonym: QS 11

Target: GTPase

Cat.No: T6197

Target: PARP

Cat.No: T6578

Target: PARP

Cat.No: T6768

Target: PARP, Wnt/beta-catenin

Cat.No: T39785L

Target: NUDIX hydrolase

Cat.No: T9165

Target: PARP

Cat.No: T15639

Target: PARP, Wnt/beta-catenin

4-amino-1,8-Naphthalimide

Cat.No: T21524

Target: PARP

Cat.No: T3168

Synonym: MN64

Target: Others, PARP, Wnt/beta-catenin

Cat.No: T6842

Target: PARP, Wnt/beta-catenin

Cat.No: T8964

Target: Others, PARP

Cat.No: T4471

Synonym: Stenoparib,UNII-9X5A2QIA7C

Target: Others, PARP

Cat.No: T1807

Synonym: JW55

Target: PARP, Wnt/beta-catenin

Cat.No: T22264

Target: PARP

1,5-Isoquinolinediol

Cat.No: T7042

Target: PARP

Cat.No: T3062

Target: PARP, Wnt/beta-catenin

Cat.No: T5058

Synonym: BGB-290

Target: PARP

Cat.No: T6339

Synonym: AG 14361,AG-14361

Target: PARP

Cat.No: T5399

Target: PARP

Cat.No: T4472

Target: PARP

Cat.No: T9593

Synonym: IMP4297

Target: PARP

Cat.No: T22414

Target: PARP

Iobenguane sulfate

Cat.No: T15588

Synonym: MIBG sulfate

Target: Others

Cat.No: T9430

Synonym: NOV140101,IDX-1197

Target: PARP

Cat.No: T7896

Synonym: RT-017290

Target: PARP

Cat.No: T3649

Synonym: BGP15,BGP-15 2HCl

Target: PARP

Cat.No: T12695

Target: PARP

Niraparib tosylate monohyrate

Cat.No: T9497

Target: PARP

Cat.No: T1878

Synonym: XAV939,NVP-XAV939

Target: PARP, Wnt/beta-catenin

Cat. No.	Product Name	Target	Signaling Pathways
T37687	Cyclic ADP-ribose ammonium	Others	Others
	Cyclic ADP-ribose ammonium (cADPR ammonium) is a powerful calcium mobilization second messenger synthesized from NAD+ by an ADP-ribosyl cyclase. It primarily raises cytosolic calcium levels through Ryanodine receptor-mediated release from the endoplasmic reticulum, while also facilitating extracellular influx through the opening of TRPM2 channels [1][2][3].
T19253	Cyclic ADP-ribose cADPR	Calcium Channel	Membrane transporter/Ion channel; Metabolism
	Cyclic ADP-ribose (cADPR) is an effective calcium mobilization second messenger, which is synthesized from NAD + by ADP-ribosyl cyclase. Cyclic ADP-ribose mainly increases cytosolic calcium through Ryanodine receptor-mediated endoplasmic reticulum release
T1723	Adenosine 5'-diphosphate 腺苷5'-二磷酸,Adenosine diphosphate,adenosine pyrophosphate,ADP	Endogenous Metabolite	Metabolism
	Adenosine 5'-diphosphate (ADP) 是一种嘌呤核糖核苷5'-二磷酸，是 ATP 在 ATP 酶作用下去磷酸化的产物。Adenosine 5'-diphosphate (adenosine pyrophosphate) 可诱导人血小板聚集并通过作用于P2T-嘌呤受体抑制受刺激的腺苷酸环化酶。
T5079	Adenosine 5'-diphosphate sodium salt 腺苷-5‘-二磷酸钠盐,Adenosine-5'-diphosphate trisodium salt,ADP sodium salt	Others; Endogenous Metabolite	Metabolism; Others
	Adenosine 5'-diphosphate sodium salt (ADP sodium salt) 是一种核苷二磷酸，是一种 ATP 酶对 ATP 去磷酸化的产物。它通过在 P2T-嘌呤受体上的作用诱导人血小板聚集并抑制刺激的腺苷酸环化酶。
T83789	7-Deazaadenosine-5'-O-diphosphate sodium 7-CH-ADP,Tubercidin 5’-diphosphate,TuDP	Others	Others
	7-Deazaadenosine-5'-O-diphosphate是一种修饰过的核苷酸和tubercidin的代谢物。该化合物通过磷酸化tubercidin形成，并进一步磷酸化生成活性代谢物7-deazaadenosine-5'-O-triphosphate。
T8184	Fucosterol 岩皂甾醇,岩藻甾醇	PARP; Endogenous Metabolite; PPAR	Chromatin/Epigenetic; DNA Damage/DNA Repair; Metabolism
	Fucosterol 是从藻类、海藻或硅藻中分离的一种甾醇，具有抗氧化、抗脂肪、降低血液胆固醇、抗糖尿病和抗癌活性。它通过抑制 PPARα和C/EBPα的表达调控脂肪生成，可用于抗肥胖试剂开发研究。
T7443	4'-Methoxychalcone 4'-甲氧基查耳酮,4'-甲氧基查尔酮	PARP; PPAR	Chromatin/Epigenetic; DNA Damage/DNA Repair; Metabolism
	4'-Methoxychalcone 通过PPARγ活化调节脂肪细胞分化，并调节参与胰岛素敏感性的脂肪组织中各种脂肪因子的表达和分泌，具抗肿瘤和抗炎活性。
T3S0156	Atractyloside potassium salt Atractyloside Dipotassium Salt,苍术苷钾盐,苍术苷二钾盐	Others	Others
	Atractyloside potassium salt (Atractyloside Dipotassium Salt) 是一种从苍术果实中分离出得到的二萜苷类化合物，具有毒性。它能抑制大鼠心脏线粒体膜的氯离子通道。它是高效、特异性的线粒体 ADP/ATP 转运 (ADP/ATP transport) 抑制剂。
T8150	Nudifloramide 1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxamide,1-甲基-6-氧代吡啶-3-甲酰胺	PARP; Endogenous Metabolite	Chromatin/Epigenetic; DNA Damage/DNA Repair; Metabolism
	Nudifloramide 是烟酰胺-腺嘌呤二核苷酸 (NAD) 降解的一种最终产物，可显著抑制PARP-1活性。
T5S2358	Dehydrocorydaline Dehydrocorydalin,脱氢紫堇碱,13-Methylpalmatine	BCL; PARP; p38 MAPK; Caspase; Parasite; Autophagy	Apoptosis; Autophagy; Chromatin/Epigenetic; DNA Damage/DNA Repair; MAPK; Microbiology/Virology; Proteases/Proteasome
	Dehydrocorydaline (13-Methylpalmatine) 是一种生物碱。它调节Bax，Bcl-2蛋白表达，激活caspase-7，caspase-8，并使PARP 失活。它能增强p38 MAPK 活化，具有抗炎、抗癌等功效。它具有强大的抗疟疾作用，并具低细胞毒性。
T6780	Benzamide Amid kyseliny benzoove,苯甲酰胺,Phenylcarboxyamide,Benzoylamide	PARP; Endogenous Metabolite	Chromatin/Epigenetic; DNA Damage/DNA Repair; Metabolism
	Benzamide (Amid kyseliny benzoove) 是聚(ADP-核糖)聚合酶的抑制剂，是苯甲酸的衍生物。
T2S2362	Dehydrocorydaline nitrate 去氢延胡索甲素硝酸盐,硝酸脱氢紫堇碱	BCL; Others; PARP; p38 MAPK; Caspase; Parasite; Autophagy	Apoptosis; Autophagy; Chromatin/Epigenetic; DNA Damage/DNA Repair; MAPK; Microbiology/Virology; Others; Proteases/Proteasome
	Dehydrocorydaline nitrate 是生物碱。Dehydrocorydaline 调节 Bax，Bcl-2蛋白表达，激活 caspase-7，caspase-8，并使 PARP 失活。它能增强 p38 MAPK 活化，具有抗炎、抗癌、抗疟疾等功效。
T10990	Dehydrocorydaline chloride 盐酸脱氢紫堇碱,13-Methylpalmatine chloride	BCL; PARP; p38 MAPK; Caspase; Parasite; Autophagy	Apoptosis; Autophagy; Chromatin/Epigenetic; DNA Damage/DNA Repair; MAPK; Microbiology/Virology; Proteases/Proteasome
	Dehydrocorydaline chloride (13-Methylpalmatine chloride) 是生物碱。Dehydrocorydaline 调节 Bax，Bcl-2蛋白表达；激活 caspase-7，caspase-8，并使 PARP 失活。它能增强 p38 MAPK 活化，具有抗炎、抗癌等功效。它具有强大的抗疟疾作用，并具低细胞毒性。
T5S1805	5,7-Dihydroxychromone 5,7-Dihydroxy-4H-Chromen-4-One,5,7-二羟基色酮,5,7-二羟基色原酮	Others; Virus Protease; PARP; Caspase; Nrf2	Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair; Immunology/Inflammation; Microbiology/Virology; Others; Proteases/Proteasome
	5,7-Dihydroxychromone (5,7-Dihydroxy-4H-Chromen-4-One) 是一种Cudrania tricuspidata 的提取物，通过激活 Nrf2/ARE 信号对 6-OHDA 诱导的氧化应激和细胞凋亡发挥神经保护作用。它抑制 6-OHDA 诱导的 SH-SY5Y 细胞中活化的caspase-3，caspase-9以及切割的PARP 表达。
TN2883	3',4'-Dimethoxyflavone	Others; PARP	Chromatin/Epigenetic; DNA Damage/DNA Repair; Others
	3',4'-Dimethoxyflavone 是类黄酮化合物的参考标准，类黄酮化合物具有多种药用活性。
T8296	5,7,4'-Trimethoxyflavone 5,7,4'-三甲氧基黄酮,芹菜素三甲醚,4',5,7-三甲氧基黄酮,4',5,7-Trimethoxyflavone	Apoptosis; PARP; Caspase	Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair; Proteases/Proteasome
	5,7,4'-Trimethoxyflavone (4',5,7-Trimethoxyflavone) 是从泰国著名的药用植物 Kaempferia parviflora 中分离出来的一种天然产物。它以浓度依赖性方式显著有效抑制 SNU-16 人胃癌细胞的增殖，诱导细胞凋亡。
T2851	Daphnetin 7,8-Dihydroxycoumarin,Daphnetol,瑞香素	EGFR; PKA; PKC; Parasite; Autophagy	Angiogenesis; Autophagy; Chromatin/Epigenetic; Cytoskeletal Signaling; JAK/STAT signaling; Microbiology/Virology; Tyrosine Kinase/Adaptors
	Daphnetin (7,8-Dihydroxycoumarin) 是从 Genus Daphne 中分离得到的香豆素衍生物，有抗氧化、抗炎、抗疟疾和解热作用，可用于凝血功能障碍、类风湿性关节炎等疾病的相关研究。
T4085	Paris saponin VII 重楼皂苷 VII,Chonglou Saponin VII,Polyphyllin-VII,Dioscinin,Paris saponin-VII	Apoptosis; BCL; Others; PARP; p38 MAPK; Akt; Caspase; P-gp; Autophagy	Apoptosis; Autophagy; Chromatin/Epigenetic; Cytoskeletal Signaling; DNA Damage/DNA Repair; MAPK; Membrane transporter/Ion channel; Neuroscience; Others; PI3K/Akt/mTOR signaling; Proteases/Proteasome
	Paris saponin VII (Dioscini) 是从延龄草的根和根茎中分离的一种甾体皂苷。它减弱线粒体膜电位，增加凋亡相关蛋白的表达，并降低Bcl-2、caspase-9、caspase-3、PARP-1和p-Akt 的蛋白表达水平。它在 K562/ADR 细胞中诱导强烈的自噬，可研究白血病。
TN6732	Oenothein B	Apoptosis; HCV Protease; Antibacterial; Antifungal	Apoptosis; Microbiology/Virology; Proteases/Proteasome
	Oenothein B 是一种聚（ADP-核糖）糖水解酶的特异性抑制剂。 Oenothein B 具有抗氧化、抗炎、抗真菌、抗 HCV 和抗肿瘤特性。
T4448	NADP
	NADP，也称为烟酰胺腺嘌呤二核苷酸磷酸，是各种代谢过程中电子转移所必需的重要氧化还原辅因子。它在促进细胞能量产生和维持细胞内氧化还原平衡方面发挥着关键作用。
T22446	NADP disodium salt Disodium NADP,Triphosphopyridine nucleotide disodium salt,beta-烟酰胺腺嘌呤二核苷酸磷酸二钠盐	Others	Others
	NADP disodium salt (Disodium NADP) 是一种氧化还原辅助因子，是一种烟酰胺腺嘌呤二核苷酸。它是代谢中电子转移的关键辅因子，可以被交替氧化 (NADP+) 和还原 (NADPH)。
T8170	Carboxyatractyloside 羧基苍术苷,Gummiferin,Carboxyatractyloside tripotassium salt	Others	Others
	Carboxyatractyloside (Carboxyatractyloside tripotassium salt) tripotassium salt 是一种 ADP/ATP 载体蛋白 (ADP/ATP carrier) 抑制剂，抑制线粒体 ADP/ATP 的转运。它是一种具有毒性的天然产物，
T6942	Picolinamide 2-Pyridinecarboxamide,2-Carbamoylpyridine,2-吡啶甲酰胺,2-Picolinamide,Picolinoylamide	PARP	Chromatin/Epigenetic; DNA Damage/DNA Repair
	Picolinamide (Picolinoylamide) 被发现是大鼠胰岛细胞核聚 (ADP-核糖) 合成酶的强抑制剂。
T4888	Phosphocreatine disodium hydrate 磷酸肌酸二钠盐,Phosphocreatine disodium salt hydrate	Others; Endogenous Metabolite	Metabolism; Others
	Phosphocreatine disodium hydrate 是内源性代谢产物的一种。
T3781	Jujuboside B 酸枣仁皂苷 B,酸枣仁皂苷B	Others	Others
	Jujuboside B 是一种提取自Zizyphus jujuba 中的活性成分，对血小板聚集具有抑制作用。
T40834	5-Hydroxymethyl-2'-deoxycytidine 5hmdC,2'-脱氧-5-(羟甲基)胞啶	PARP	Chromatin/Epigenetic; DNA Damage/DNA Repair
	5-Hydroxymethyl-2'-deoxycytidine 是 DNA 中 5-methyl-2'-deoxycytidine (5-mdC) 的氧化衍生物，引起DNA损伤反应，染色体畸变，复制叉损伤和细胞活力丧失。5-Hydroxymethyl-2’-deoxycytidine 复制叉不稳定性与染色质上聚（ADP-核糖）聚合酶1（PARP1）的存在有关。
T5S0896	Loureirin A 龙血素 A,龙血素A	Akt; PI3K	Cytoskeletal Signaling; PI3K/Akt/mTOR signaling
	Loureirin A 是一种黄酮类物质，从龙血树中分离得到，能够降低Akt 的磷酸化，具有抗血小板聚集作用。
T6S2391	L-Chicoric Acid (-)-Chicoric acid,trans-Caffeoyltartaric acid,Chicoric acid,L-菊苣酸,dicaffeoyltartaric acid,菊苣酸	Others; HIV Protease	Microbiology/Virology; Others; Proteases/Proteasome
	L-Chicoric Acid (trans-Caffeoyltartaric acid) 是一种二咖啡酰酒石酸，是一种选择性可逆的 HIV-1 整合酶抑制剂，IC50约为 100 nM。它还可抑制 HIV-1 复制。
T2860	Vanillyl Alcohol 4-Hydroxy-3-methoxybenzenemethanol,3-Methoxy-4-hydroxybenzyl alcohol,4-Hydroxy-3-methoxybenzyl alcohol,香兰醇,Vanillin alcohol,Vanillic alcohol	Apoptosis; Others	Apoptosis; Others
	Vanillyl Alcohol (3-Methoxy-4-hydroxybenzyl alcohol) 是一种酚类醇，具有抗血管生成、抗惊厥、抗炎、抗氧化、神经保护和抗伤害活性。它由香兰素衍生而来，在食品和饮料中用作调味剂。
T4786	D-Ribose(mixture of isomers) D-Ribose,D-(-)-Ribose,D-(-)-核糖	Others; Endogenous Metabolite	Metabolism; Others
	D-Ribose(mixture of isomers) (D-(-)-Ribose) 是 ATP 的糖部分，可作为能量增强剂，被广泛用作慢性疲劳综合症和心肌能量代谢的代谢疗法补充剂。它在蛋白质糖化中具有特性，能够 RAGE 依赖的方式诱导 NF-Κb 炎症。
T7982	3,6-Dihydroxyflavone	Others	Others
	3,6-Dihydroxyflavone 是一种抗癌剂。它能够提高细胞内氧化应激和脂质过氧化。它是能够根据剂量和时间依赖性地降低细胞活力，并活化半胱天冬酶级联、切割聚 (ADP-核糖) 聚合酶 (PARP) 诱导细胞凋亡。
T4883	Creatine Methylguanidoacetic acid,肌酸	Endogenous Metabolite	Metabolism
	Creatine (Methylguanidoacetic acid) 是一种内源性氨基酸代谢物，在细胞能量中发挥重要作用，尤其是在肌肉和大脑中。
T7032	Eupatorin	Others; P450	Metabolism; Others
	Eupatorin 是天然存在的黄酮，可捕获 G2-M 细胞周期，激活多个 caspase、细胞色素 C 的释放、多聚 (ADP-核糖) 聚合酶的裂解，促使凋亡细胞死亡。
T15721	Latrunculin A LAT-A	Others	Others
	Latrunculin A is a toxin isolated from the red sea sponge Latrunculia magnifica. Latrunculin A binds to actin monomers and it also inhibits polymerization of actin (Kds: 0.1, 0.4, 4.7 μM, and 0.19 μM for ATP-actin, ADP-Pi-actin, ADP-actin, and G-actin, re
TN3069	4beta-Carboxy-19-nortotarol	NADPH-oxidase	Immunology/Inflammation
	4 beta-Carboxy-19-nortotarol can inhibit microsomal lipid peroxidation induced by Fe(III)-ADP/NADPH and mitochondrial lipid peroxidation induced by Fe(III)-ADP/ NADH, it inhibits linoleic acid autoxidation but not generation of superoxide anion.
T25211	CC 1014 CC1014,CC-1014,NSC-356885,NSC356885,NSC 356885	Others	Others
	CC 1014 is a polypeptide antibiotic isolated from Penicillium lilacinum that inhibits phosphorylation of ADP, Mg ATPase.
T17273	YM-254890 YM254890,YM 254890	P2Y Receptor	GPCR/G Protein; Neuroscience
	YM-254890 是一种从 Chromobacterium sp 中分离的大环己肽，是一种具有选择性和高效性的 Gαq/11 蛋白抑制剂，抑制 ADP 诱导的血小板凝集，抑制 G 蛋白信号传导。
T83460	11-O-β-D-glucopyranosyl thamnosmonin
	11-O-β-D-glucopyranosyl thamnosmonin是一种香豆素苷，能够从Angelica apaensis根部提取。该化合物对PAF、AA和ADP诱发的兔血小板聚集表现出轻度的抑制效果。
TN1310	6-Hydroxykaempferol 3,6-diglucoside	Others	Others
	6-Hydroxykaempferol 3,6-di-O-glucoside and 6-hydroxykaempferol 3,6,7-tri-O-glucoside can inhibit platelet aggregation induced by collagen, they also show weak inhibitory effects on the adenosine 5'-diphosphate (ADP)- induced platelet aggregation.
T37714	Fuscin	Others	Others
	Fuscin is a quinonoid fungal metabolite originally isolated from O. fuscum that has diverse biological activities. It inhibits binding of the ADP/ATP translocase inhibitor atractyloside to rat liver mitochondria in an ADP-dependent manner when used at a concentration of 50 μM in a radioligand binding assay. Fuscin (20 μM) reduces the glutathione content of rat liver mitochondria to 28% of controls and inhibits NADH oxidation in sonicated pigeon heart mitochondria preparations in a concentration-...
TN1309	6-Hydroxykaempferol-3,6,7-triglucoside	Others	Others
	6-Hydroxykaempferol 3,6,7-tri-O-glucoside and 6-hydroxykaempferol 3,6-di-O-glucoside can inhibit platelet aggregation induced by collagen, they also show weak inhibitory effects on the adenosine 5'-diphosphate (ADP)- induced platelet aggregation.
T38015	Herquline A	Others	Others
	Herquline A is an alkaloid fungal metabolite originally isolated from P. herquei. It inhibits cell death induced by influenza A strain A/PR/8/34 in MDCK cells with an IC50 value of 10 μg/ml and inhibits viral replication in a plaque assay in a concentration-dependent manner. Herquline A also inhibits platelet aggregation induced by ADP and platelet-activating factor (PAF) in vitro (IC50s = 180 and 240 μM, respectively).
TN6924	Anhydrosafflor yellow B (2S,3S)-6,7-dihydroxy-5-[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]-2-[(1S,2R,3R)-1,2,3,4-tetrahydroxybutyl]-3-{2,3,4-trihydroxy-5-[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]-6-oxo-3-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]cyclohexa-1,4-dien-1,脱水红花黄色素B,AHSYB	Others	Others
	Anhydrosafflor yellow B ((2S,3S)-6,7-dihydroxy-5-[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]-2-[(1S,2R,3R)-1,2,3,4-tetrahydroxybutyl]-3-{2,3,4-trihydroxy-5-[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]-6-oxo-3-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]cyclohexa-1,4-dien-1) 是从红花中分离出来的，可抑制 ADP 诱导的血小板聚集，在体外表现出显着的抗氧化作用，并对 H2O2 诱导的细胞毒性具有一定的活性。
TN4046	Excisanin A	MMP; FAK; PARP; GSK-3; NF-κB; Wnt/beta-catenin; Akt; Caspase; PI3K; Prostaglandin Receptor; JNK	Angiogenesis; Apoptosis; Chromatin/Epigenetic; Cytoskeletal Signaling; DNA Damage/DNA Repair; GPCR/G Protein; Immunology/Inflammation; MAPK; NF-κB; PI3K/Akt/mTOR signaling; Proteases/Proteasome; Stem Cells; Tyrosine Kinase/Adaptors
	ExcisaninA may be a potent inhibitor of AKT signaling pathway in tumor cells, it can inhibit invasion by suppressing MMP-2 and MMP-9 expression, it may be a potential anti-metastatic chemotherapeutic agent for the treatment of breast cancer. Excisanin A shows comparable inhibitory effects on the LPS-induced production of NO and PGE2, and activation of NF-kappaB without affecting cell viability.Excisanin A induces apoptosis in colon cancer cell line SW620 as determined by Annexin V staining, the ...
TN6014	Norcepharadione B 鱼腥草
	Norcepharadione B shows good inhibitory activity against the replication of HSV-1, it also shows antimalarial activity with EC50 values of 7.5mug/ml. Norcepharadione B exhibits significant cytotoxicity against five human tumor cell lines (A-549, SK-OV-3,
TN4664	Norarmepavine	Others	Others
	N-norarmepavine shows significant cytotoxic activities against HL-60 carcinoma cell line with inhibitory ratios of 51.43% at concentration of 1 x 10(-5) M. Norarmepavine shows inhibition against Trypanosoma cruzi. D-(+)- N-norarmepavine exhibits significa
T73403	Aviculin	Others	Others
	Aviculin 是一种木聚糖苷，是一种有效的抗癌剂 (anticanceragent)。Aviculin 可降低 MCF-7 细胞代谢活性到 50% 以下，IC50为 75.47 μM。Aviculin 通过内在凋亡途径诱导乳腺癌细胞凋亡 (apoptosis)。Aviculin 增加了 caspase-9、caspase-7和 PARP 的表达。Aviculin 使 Bax/Bcl-2 的比值升高。
T35624	Ajoene	Others	Others
	Ajoene is a disulfide that has been found inA. sativumand has diverse biological activities, including antibacterial, anticancer, antiplatelet, and antioxidant properties.1,2,3,4It is active against Gram-positive (MICs = 5-160 &#181g/ml) and Gram-negative bacteria (MICs = 136-200 &#181g/ml), as well as yeasts (MICs = 10-20 &#181g/ml).1Ajoene is cytotoxic to mouse melanoma cells (IC50= 18 &#181M), as well as human colon, lung, mammary, and pancreatic cancer cells (IC50s = 7-41 &#181M).2It reduces...

天然产物

Cyclic ADP-ribose ammonium

Cat.No: T37687

Target: Others

Cyclic ADP-ribose

Cat.No: T19253

Synonym: cADPR

Target: Calcium Channel

Adenosine 5'-diphosphate

Cat.No: T1723

Synonym: 腺苷5'-二磷酸,Adenosine diphosphate,adenosine pyrophosphate,ADP

Target: Endogenous Metabolite

Adenosine 5'-diphosphate sodium salt

Cat.No: T5079

Synonym: 腺苷-5‘-二磷酸钠盐,Adenosine-5'-diphosphate trisodium salt,ADP sodium salt

Target: Others, Endogenous Metabolite

7-Deazaadenosine-5'-O-diphosphate sodium

Cat.No: T83789

Synonym: 7-CH-ADP,Tubercidin 5’-diphosphate,TuDP

Target: Others

Cat.No: T8184

Synonym: 岩皂甾醇,岩藻甾醇

Target: PARP, Endogenous Metabolite, PPAR

4'-Methoxychalcone

Cat.No: T7443

Synonym: 4'-甲氧基查耳酮,4'-甲氧基查尔酮

Target: PARP, PPAR

Atractyloside potassium salt

Cat.No: T3S0156

Synonym: Atractyloside Dipotassium Salt,苍术苷钾盐,苍术苷二钾盐

Target: Others

Cat.No: T8150

Synonym: 1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxamide,1-甲基-6-氧代吡啶-3-甲酰胺

Target: PARP, Endogenous Metabolite

Dehydrocorydaline

Cat.No: T5S2358

Synonym: Dehydrocorydalin,脱氢紫堇碱,13-Methylpalmatine

Target: BCL, PARP, p38 MAPK, Caspase, Parasite, Autophagy

Cat.No: T6780

Synonym: Amid kyseliny benzoove,苯甲酰胺,Phenylcarboxyamide,Benzoylamide

Target: PARP, Endogenous Metabolite

Dehydrocorydaline nitrate

Cat.No: T2S2362

Synonym: 去氢延胡索甲素硝酸盐,硝酸脱氢紫堇碱

Target: BCL, Others, PARP, p38 MAPK, Caspase, Parasite, Autophagy

Dehydrocorydaline chloride

Cat.No: T10990

Synonym: 盐酸脱氢紫堇碱,13-Methylpalmatine chloride

Target: BCL, PARP, p38 MAPK, Caspase, Parasite, Autophagy

5,7-Dihydroxychromone

Cat.No: T5S1805

Synonym: 5,7-Dihydroxy-4H-Chromen-4-One,5,7-二羟基色酮,5,7-二羟基色原酮

Target: Others, Virus Protease, PARP, Caspase, Nrf2

3',4'-Dimethoxyflavone

Cat.No: TN2883

Target: Others, PARP

5,7,4'-Trimethoxyflavone

Cat.No: T8296

Synonym: 5,7,4'-三甲氧基黄酮,芹菜素三甲醚,4',5,7-三甲氧基黄酮,4',5,7-Trimethoxyflavone

Target: Apoptosis, PARP, Caspase

Cat.No: T2851

Synonym: 7,8-Dihydroxycoumarin,Daphnetol,瑞香素

Target: EGFR, PKA, PKC, Parasite, Autophagy

Paris saponin VII

Cat.No: T4085

Synonym: 重楼皂苷 VII,Chonglou Saponin VII,Polyphyllin-VII,Dioscinin,Paris saponin-VII

Target: Apoptosis, BCL, Others, PARP, p38 MAPK, Akt, Caspase, P-gp, Autophagy

Cat.No: TN6732

Target: Apoptosis, HCV Protease, Antibacterial, Antifungal

Cat.No: T4448

NADP disodium salt

Cat.No: T22446

Synonym: Disodium NADP,Triphosphopyridine nucleotide disodium salt,beta-烟酰胺腺嘌呤二核苷酸磷酸二钠盐

Target: Others

Carboxyatractyloside

Cat.No: T8170

Synonym: 羧基苍术苷,Gummiferin,Carboxyatractyloside tripotassium salt

Target: Others

Cat.No: T6942

Synonym: 2-Pyridinecarboxamide,2-Carbamoylpyridine,2-吡啶甲酰胺,2-Picolinamide,Picolinoylamide

Target: PARP

Phosphocreatine disodium hydrate

Cat.No: T4888

Synonym: 磷酸肌酸二钠盐,Phosphocreatine disodium salt hydrate

Target: Others, Endogenous Metabolite

Cat.No: T3781

Synonym: 酸枣仁皂苷 B,酸枣仁皂苷B

Target: Others

5-Hydroxymethyl-2'-deoxycytidine

Cat.No: T40834

Synonym: 5hmdC,2'-脱氧-5-(羟甲基)胞啶

Target: PARP

Cat.No: T5S0896

Synonym: 龙血素 A,龙血素A

Target: Akt, PI3K

L-Chicoric Acid

Cat.No: T6S2391

Synonym: (-)-Chicoric acid,trans-Caffeoyltartaric acid,Chicoric acid,L-菊苣酸,dicaffeoyltartaric acid,菊苣酸

Target: Others, HIV Protease

Vanillyl Alcohol

Cat.No: T2860

Synonym: 4-Hydroxy-3-methoxybenzenemethanol,3-Methoxy-4-hydroxybenzyl alcohol,4-Hydroxy-3-methoxybenzyl alcohol,香兰醇,Vanillin alcohol,Vanillic alcohol

Target: Apoptosis, Others

D-Ribose(mixture of isomers)

Cat.No: T4786

Synonym: D-Ribose,D-(-)-Ribose,D-(-)-核糖

Target: Others, Endogenous Metabolite

3,6-Dihydroxyflavone

Cat.No: T7982

Target: Others

Cat.No: T4883

Synonym: Methylguanidoacetic acid,肌酸

Target: Endogenous Metabolite

Cat.No: T7032

Target: Others, P450

Cat.No: T15721

Synonym: LAT-A

Target: Others

4beta-Carboxy-19-nortotarol

Cat.No: TN3069

Target: NADPH-oxidase

Cat.No: T25211

Synonym: CC1014,CC-1014,NSC-356885,NSC356885,NSC 356885

Target: Others

Cat.No: T17273

Synonym: YM254890,YM 254890

Target: P2Y Receptor

11-O-β-D-glucopyranosyl thamnosmonin

Cat.No: T83460

6-Hydroxykaempferol 3,6-diglucoside

Cat.No: TN1310

Target: Others

Cat.No: T37714

Target: Others

6-Hydroxykaempferol-3,6,7-triglucoside

Cat.No: TN1309

Target: Others

Cat.No: T38015

Target: Others

Anhydrosafflor yellow B

Cat.No: TN6924

Synonym: (2S,3S)-6,7-dihydroxy-5-[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]-2-[(1S,2R,3R)-1,2,3,4-tetrahydroxybutyl]-3-{2,3,4-trihydroxy-5-[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]-6-oxo-3-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]cyclohexa-1,4-dien-1,脱水红花黄色素B,AHSYB

Target: Others

Cat.No: TN4046

Target: MMP, FAK, PARP, GSK-3, NF-κB, Wnt/beta-catenin, Akt, Caspase, PI3K, Prostaglandin Receptor, JNK

Norcepharadione B

Cat.No: TN6014

Synonym: 鱼腥草

Cat.No: TN4664

Target: Others

Cat.No: T73403

Target: Others

Cat.No: T35624

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-01188	PARP Protein, Human, Recombinant (His) ADPRT1,ADPRT,pADPRT-1,PPOL,ARTD1,...	Human	Baculovirus Insect Cells
	PARP Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 114.5 kDa and the accession number is A0A024R3T8.
TMPJ-00190	CD38 Protein, Mouse, Recombinant (hFc) ADP-ribosyl cyclase 1,cyclic ADP-ribose hy...	Mouse	HEK293 Cells
	CD38, also called ADP-ribosyl cyclase, is a Type II integral membrane protein with 301 amino acids in length that belongs to the ADP-ribosyl cyclase family.It synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. And also moonlights as a receptor in cells of the immune system. CD38 is expressed in B and T lymphocytes, osteoclasts, and in cardiac, pancreatic, liver and kidney cells. Th...
TMPH-01945	TIPARP Protein, Human, Recombinant (His) ADP-ribosyltransferase diphtheria toxin-like 14,Pol...	Human	Baculovirus Insect Cells
	TIPARP Protein, Human, Recombinant (His) is expressed in Baculovirus.
TMPY-04209	ART1 Protein, Cynomolgus, Recombinant (His) ADP-ribosyltransferase 1	Cynomolgus	HEK293 Cells
	ART1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.7 kDa and the accession number is A0A2K5WCR3.
TMPH-01881	PARP2 Protein, Human, Recombinant (GST & His) Protein poly-ADP-ribosyltransferase PARP2,NAD(+)	Human	Baculovirus Insect Cells
	PARP2 Protein, Human, Recombinant (GST & His) is expressed in Baculovirus insect cells with N-GST and C-6xHis tag. The predicted molecular weight is 92.8 kDa and the accession number is Q9UGN5.
TMPH-01880	PARP2 Protein, Human, Recombinant (His) Protein poly-ADP-ribosyltransferase PARP2,Poly [	Human	E. coli
	PARP2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 72.2 kDa and the accession number is Q9UGN5.
TMPY-00583	ADPRH Protein, Human, Recombinant (His) ADP-ribosylarginine hydrolase,ARH1	Human	E. coli
	Cholera toxin (CT) produced by Vibrio cholerae causes the devastating diarrhea of cholera by catalyzing the ADP-ribosylation of the alpha subunit of the intestinal Gs protein (Gsalpha), leading to characteristic water and electrolyte losses. Mammalian cells contain ADP-ribosyltransferases similar to CT and an ADP-ribosyl(arginine)protein hydrolase (ADPRH), which cleaves the ADP-ribose-(arginine)protein bond, regenerating native protein and completing an ADP-ribosylation cycle. CT-catalyzed ADP-r...
TMPH-01804	OARD1 Protein, Human, Recombinant (His & Myc) OARD1,ADP-ribose glycohydrolase OARD1,Terminal ...	Human	E. coli
	OARD1 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 24.3 kDa and the accession number is Q9Y530.
TMPH-01943	PARP4 Protein, Human, Recombinant (His) Poly [ADP-ribose] polymerase 4,ADP-ribosyl...	Human	E. coli
	PARP4 Protein, Human, Recombinant (His) is expressed in E. coli.
TMPY-03796	ARF3 Protein, Human, Recombinant (His) ADP-ribosylation factor 3	Human	E. coli
	ARF3, also known as ADP-ribosylation factor 3, belongs to the RAS superfamily. Members of this family include ARF1, ARF2, ARF3, ARF4, ARF5 and ARF6. ARF3 gene is a member of the human ARF gene family. These genes encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. ARF3 functions as an allosteric activator of the cholera toxin subunit, an ADP-ribosyltrans...
TMPH-01879	PARP11 Protein, Human, Recombinant (His) PARP11,Poly [ADP-ribose] polymerase 11,Protein mono...	Human	E. coli
	Mono-ADP-ribosyltransferase that mediates mono-ADP-ribosylation of target proteins. Plays a role in nuclear envelope stability and nuclear remodeling during spermiogenesis. PARP11 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 41.0 kDa and the accession number is Q9NR21.
TMPY-03386	ART3 Protein, Human, Recombinant (His) ADP-ribosyltransferase 3,ARTC3	Human	HEK293 Cells
	ART3 is an arginine-specific ADP-ribosyltransferase which belongs to the Arg-specific ADP-ribosyltransferase family. ART3 catalyzes a reversible reaction which modifies proteins by the addition or removal of ADP-ribose to an arginine residue to regulate the function of the modified protein. It is expressed specifically in testis. ART3 pseudogene is located on chromosome 11. ART3 was identified as a susceptibility gene for non-obstructive azoospermia (NOA). It is a novel therapeutic target in the...
TMPJ-00202	CD157 Protein, Human, Recombinant (hFc) Cyclic ADP-ribose hydrolase 2,cADPr hydrol...	Human	HEK293 Cells
	The cluster of differentiation (CD) system is a glycosyl phosphatidylinositol anchored membrane protein that belongs to the CD38 family.It is generally used in immunophynotyping. CD157 was discovered in a bone marrow stromal cell line where it facilitates pre-B-cell growth. CD157 is a bifunctional ectoenzyme that exhibits both ADP-ribosyl cyclase and cyclic ADP ribose hydrolase activities followed with CD38. It plays a role in rheumatoid arthritis (RA) due to its enhanced expression in RA-derive...
TMPY-03868	ARF5 Protein, Human, Recombinant (His) ARF5,ADP ribosylation factor 5	Human	E. coli
	ARF5, also known as ADP-ribosylation factor 5, belongs to the small GTPase superfamily, Arf family. Members of this family stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. ARF5 functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. ARF5 Is involved in protein trafficking. ARF5 may also modulate vesicle budding and uncoating within the Golgi apparatus.
TMPY-06637	ARF1 Protein, Human, Recombinant (GST) ARF1,ADP ribosylation factor 1	Human	E. coli
	ARF1 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with GST tag. The predicted molecular weight is 47.00 kDa and the accession number is P84077.
TMPH-00907	MACROD1 Protein, Human, Recombinant (His) MACROD1,Protein LRP16,O-acetyl-ADP-ribose deacetyla...	Human	E. coli
	MACROD1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 41.5 kDa and the accession number is Q9BQ69.
TMPH-00908	MACROD1 Protein, Human, Recombinant (His & Myc) ADP-ribose glycohydrolase MACROD1,MACROD1,[Protein ...	Human	Baculovirus Insect Cells
	MACROD1 Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus.
TMPY-06746	ARF1 Protein, Human, Recombinant (His & Avi), Biotinylated ADP ribosylation factor 1,ARF1	Human	E. coli
	ARF1 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in E. coli expression system with His and Avi tag. The predicted molecular weight is 23.33 kDa and the accession number is P84077.
TMPH-01944	PARP9 Protein, Human, Recombinant (His & Myc) Poly [ADP-ribose] polymerase 9,ADP-ribosyl...	Human	HEK293 Cells
	PARP9 Protein, Human, Recombinant (His & Myc) is expressed in HEK293.
TMPY-03312	ART4/CD297 Protein, Rat, Recombinant (His) ADP-ribosyltransferase 4 (Dombrock blood group)	Rat	HEK293 Cells
	ART4/CD297 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.4 kDa and the accession number is F1MA10.
TMPY-03544	ART4/CD297 Protein, Cynomolgus, Recombinant (hFc) ADP-ribosyltransferase 4 (Dombrock blood group)	Cynomolgus	HEK293 Cells
	ART4/CD297 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 54.7 kDa and the accession number is G7PJY0.
TMPH-01882	PARP9 Protein, Human, Recombinant (His) PARP9,Poly [ADP-ribose] polymerase 9,ADP-r...	Human	E. coli
	PARP9 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 30.0 kDa and the accession number is Q8IXQ6.
TMPY-04130	ARF1 Protein, Human, Recombinant (His) ARF1,ADP ribosylation factor 1	Human	E. coli
	ARF1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 22.5 kDa and the accession number is P84077.
TMPH-01942	PARP14 Protein, Human, Recombinant (His & Myc) Protein mono-ADP-ribosyltransferase PARP14,B aggres...	Human	HEK293 Cells
	PARP14 Protein, Human, Recombinant (His & Myc) is expressed in HEK293.
TMPY-03777	ART4/CD297 Protein, Cynomolgus, Recombinant (His) ADP-ribosyltransferase 4 (Dombrock blood group)	Cynomolgus	HEK293 Cells
	ART4/CD297 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 29.1 kDa and the accession number is G7PJY0.
TMPH-01941	PARP12 Protein, Human, Recombinant (His & Myc) Protein mono-ADP-ribosyltransferase PARP12,PARP12,<...	Human	E. coli
	PARP12 Protein, Human, Recombinant (His & Myc) is expressed in E. coli.
TMPH-03026	CARDS Protein, Mycoplasma pneumoniae, Recombinant (His & Myc) ADP-ribosylating toxin CARDS,CARDX TX,ADP-...	Mycoplasma pneumoniae	E. coli
	Acts as an ADP-ribosylating toxin, which may transfer the ADP-ribosyl group from NAD(+) to specific amino acids in target proteins. Elicits cytopathic effects in mammalian cells, such as disorganization and disruption of respiratory epithelial integrity in tracheal epithelium and vacuolization in the cytoplasm of CHO and HeLa cells.
TMPH-00906	SLC25A6 Protein, Human, Recombinant (His & KSI) ADP,ATP carrier protein 3,SLC25A6,ADP,ATP ...	Human	E. coli
	SLC25A6 Protein, Human, Recombinant (His & KSI) is expressed in E. coli expression system with N-6xHis-KSI tag. The predicted molecular weight is 20.2 kDa and the accession number is P12236.
TMPY-01620	MDGA2 Protein, Mouse, Recombinant (His) 6720489L24Rik,Adp,MAM domain containing glycosylpho...	Mouse	HEK293 Cells
	MAM domain-containing glycosylphosphatidylinositol anchor protein 2, also known as MAM domain-containing protein 1, MDGA2, and MAMDC1, is a cell membrane protein that contains six Ig-like (immunoglobulin-like) domains and one MAM domain. Analyses of the full-length coding region of MDGA1 and MDGA2 indicate that they encode proteins that comprise a novel subgroup of the Ig superfamily and have a unique structural organization consisting of six immunoglobulin (Ig)-like domains followed by a single...
TMPY-02822	ART4/CD297 Protein, Mouse, Recombinant (hFc) 4432404K01Rik,DOK1,ADP-ribosyltransferase 4 (Dombro...	Mouse	HEK293 Cells
	ART4/CD297 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 53.7 kDa and the accession number is Q9CRA0.
TMPH-00432	Diphtheria toxin Protein, Corynephage omega, Recombinant (His & Myc) Diphtheria toxin,DT,NAD(+)--diphthamide ADP-ribosyl...	Corynephage omega	E. coli
	Diphtheria toxin Protein, Corynephage omega, Recombinant (His & Myc) is expressed in E. coli.
TMPY-06532	ART1 Protein, Human, Recombinant (His) ADP-ribosyltransferase 1,CD296,ARTC1,ART2,RT6	Human	HEK293 Cells
	ART1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.55 kDa and the accession number is NP_004305.2.
TMPH-01822	P2Y1 Protein, Human, Recombinant (His) P2Y purinoceptor 1,ADP receptor,Purinergic receptor...	Human	E. coli
	Receptor for extracellular adenine nucleotides such as ADP. In platelets, binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and ultimately platelet aggregation. P2Y1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with C-6xHis tag. The predicted molecular weight is 12.4 kDa and the accession number is P47900.
TMPY-02738	ART4/CD297 Protein, Mouse, Recombinant (His) ADP-ribosyltransferase 4 (Dombrock blood group),ART...	Mouse	HEK293 Cells
	ART4/CD297 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.2 kDa and the accession number is EDL10575.1.
TMPH-03168	Exotoxin A Protein, Pseudomonas aeruginosa, Recombinant (His & KSI) NAD(+)--diphthamide ADP-ribosyltransferase,Exotoxin...	Pseudomonas aeruginosa	E. coli
	An NAD-dependent ADP-ribosyltransferase (ADPRT). Catalyzes the transfer of the ADP ribosyl moiety of oxidized NAD (NAD(+)) onto eukaryotic elongation factor 2 (eEF-2) thus arresting protein synthesis. Has an LD(50) of 65 ng/ml against the human lung epithelial cell line C38. Exotoxin A Protein, Pseudomonas aeruginosa, Recombinant (His & KSI) is expressed in E. coli expression system with N-6xHis-KSI tag. The predicted molecular weight is 39.9 kDa and the accession number is P11439.
TMPY-03500	ARL2BP Protein, Human, Recombinant (His) RP66,ADP-ribosylation factor-like 2 binding protein...	Human	E. coli
	ADP-ribosylation factor (ARF)-like proteins (ARLs) comprise a functionally distinct group of the ARF family of RAS-related GTPases. ARL2BP binds to ARL2.GTP with high affinity but does not interact with ARL2.GDP, activated ARF, or RHO proteins. The lack of detectable membrane association of ARL2BP or ARL2 upon activation of ARL2 is suggestive of actions distinct from those of the ARFs. ARL2BP is considered to be the first ARL2-specific effector identified, due to its interaction with ARL2....
TMPY-00344	ARL6IP6 Protein, Human, Recombinant (mFc) PFAAP1,AIP-6,ADP-ribosylation factor-like 6 interac...	Human	HEK293 Cells
	It had been found that a homozygous truncating mutation in ARL6IP6 as the likely cause of a syndromic form of CMTC associated with major dysmorphism, developmental delay, transient ischemic attacks and cerebral vascular malformations. This gene was previously implicated by genome wide association study (GWAS) as a susceptibility locus to ischemic stroke in young adults. We identify ARL6IP6 as a novel candidate gene for a syndromic form of CMTC. This suggests that ischemic stroke or transient isc...
TMPH-00207	PTX S1 Protein, Bordetella pertussis, Recombinant (His) Islet-activating protein S1,Pertussis toxin subunit 1,NAD-de...	Bordetella pertussis	P. pastoris (Yeast)
	S1 is an NAD-dependent ADP-ribosyltransferase, which plays a crucial role in the pathogenesis of B.pertussis causing disruption of normal host cellular regulation. It catalyzes the ADP-ribosylation of a cysteine in the alpha subunit of host heterotrimeric G proteins. In the absence of G proteins it also catalyzes the cleavage of NAD(+) into ADP-ribose and nicotinamide. It irreversibly uncouples the G-alpha GTP-binding proteins from their membrane receptors. PTX S1 Protein, Bordetella pertussis, ...
TMPY-02421	PARP3 Protein, Human, Recombinant (His & GST) ARTD3,IRT1,ADPRTL2,ADPRTL3,poly (ADP	Human	Baculovirus Insect Cells
	Poly(ADP-ribose) polymerase 3 (PARP3) is an important member of the PARP family and shares high structural similarities with both PARP1 and PARP2. Poly(ADP-ribose) polymerase 3 (PARP3), a critical player in cellular response to DNA double-strand breaks (DSBs), plays an essential role in the maintenance of genome integrity. The ADP ribosyl transferase [poly(ADP-ribose) polymerase] ARTD3(PARP3) is a newly characterized member of the ARTD(PARP) family that catalyzes the reaction of ADP ribosylation...
TMPY-02465	PARP Protein, Mouse, Recombinant (His) AI893648,Adprp,5830444G22Rik,C80510,sPARP-1,poly (<...	Mouse	Baculovirus Insect Cells
	PARP Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 115 kDa and the accession number is Q921K2.
TMPH-01742	SIRT6 Protein, Human, Recombinant (GST) Protein mono-ADP-ribosyltransferase sirtuin-6,NAD-d...	Human	E. coli
	SIRT6 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 66.0 kDa and the accession number is Q8N6T7.
TMPH-01743	NADP-ME Protein, Human, Recombinant (His) NADP-dependent malic enzyme, mitochondrial,ME3,Mali...	Human	E. coli
	NADP-ME Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 67.2 kDa and the accession number is Q16798.
TMPH-00553	Fructose 5-dehydrogenase [NADP(+)] Protein, Erwinia citreus, Recombinant (His & KSI) Fructose 5-dehydrogenase [NADP(+)],5-ketofructose r...	Erwinia citreus	E. coli
	Fructose 5-dehydrogenase [NADP(+)] Protein, Erwinia citreus, Recombinant (His & KSI) is expressed in E. coli.
TMPH-03283	CD39 Protein, Rat, Recombinant (His) ATP diphosphohydrolase,Entpd1,Nucleoside triphosphate diphos...	Rat	Baculovirus Insect Cells
	In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Could also be implicated in the prevention of platelet aggregation by hydrolyzing platelet-activating ADP to AMP. Hydrolyzes ATP and ADP equally well.
TMPH-03284	CD39 Protein, Rat, Recombinant (E. coli, His) Entpd1,ATP-DPH,Ecto-ATP diphosphohydrolase 1,CD39,Ecto-ATPas...	Rat	E. coli
	In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Could also be implicated in the prevention of platelet aggregation by hydrolyzing platelet-activating ADP to AMP. Hydrolyzes ATP and ADP equally well.
TMPH-01091	CHD1L Protein, Human, Recombinant (His & SUMO) Amplified in liver cancer protein 1,CHD1L,ALC1,Chromodomain-...	Human	E. coli
	DNA helicase which plays a role in chromatin-remodeling following DNA damage. Targeted to sites of DNA damage through interaction with poly(ADP-ribose) and functions to regulate chromatin during DNA repair. Able to catalyze nucleosome sliding in an ATP-dependent manner. Helicase activity is strongly stimulated upon poly(ADP-ribose)-binding. CHD1L Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 37.3 kDa an...
TMPH-00689	Propionate kinase Protein, E. coli O6:H1, Recombinant (His & Myc) tdcD,Propionate kinase	E. coli	E. coli
	Catalyzes the conversion of propionyl phosphate and ADP to propionate and ATP. Propionate kinase Protein, E. coli O6:H1, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 50.4 kDa and the accession number is P59244.
TMPH-00863	5-oxoprolinase/OPLAH Protein, Human, Recombinant (His & Myc) 5-oxo-L-prolinase,5-OPase,Pyroglutamase,OPLAH	Human	E. coli
	Catalyzes the cleavage of 5-oxo-L-proline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. 5-oxoprolinase/OPLAH Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 17.4 kDa and the accession number is O14841.
TMPH-03194	GCK Protein, Pyrococcus horikoshii, Recombinant (His & Myc) Glycerate 2-kinase,gck,2-phosphoglycerate forming glycerate ...	Pyrococcus horikoshii	E. coli
	Catalyzes the ATP-dependent phosphorylation of D-glycerate to 2-phosphoglycerate. It can also utilize GTP, CTP, UTP, ADP or pyrophosphate as phosphate donor. GCK Protein, Pyrococcus horikoshii, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 54.8 kDa and the accession number is O58231.
TMPJ-00384	PFKM Protein, Human, Recombinant (His) Phosphofructo-1-kinase isozyme A,Phosphohexokinase,PFKX,6-ph...	Human	HEK293 Cells
	6-phosphofructokinase, muscle type is a muscle-type isozyme that in humans is encoded by the PFKM gene. It belongs to the phosphofructokinase family and Two domains subfamily. PFKM functions as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-bisphosphate. PFK1 converts fructose 6-phosphate and ATP into fructose 1,6-bisphosphate (through PFK-1), fructose 2,6-bisphosphate (through PFK-2) and ADP.
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重组蛋白

PARP Protein, Human, Recombinant (His)

Cat.No: TMPY-01188

Species: Human

Expression System: Baculovirus Insect Cells

CD38 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPJ-00190

Species: Mouse

Expression System: HEK293 Cells

TIPARP Protein, Human, Recombinant (His)

Cat.No: TMPH-01945

Species: Human

Expression System: Baculovirus Insect Cells

ART1 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPY-04209

Species: Cynomolgus

Expression System: HEK293 Cells

PARP2 Protein, Human, Recombinant (GST & His)

Cat.No: TMPH-01881

Species: Human

Expression System: Baculovirus Insect Cells

PARP2 Protein, Human, Recombinant (His)

Cat.No: TMPH-01880

Species: Human

Expression System: E. coli

ADPRH Protein, Human, Recombinant (His)

Cat.No: TMPY-00583

Species: Human

Expression System: E. coli

OARD1 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01804

Species: Human

Expression System: E. coli

PARP4 Protein, Human, Recombinant (His)

Cat.No: TMPH-01943

Species: Human

Expression System: E. coli

ARF3 Protein, Human, Recombinant (His)

Cat.No: TMPY-03796

Species: Human

Expression System: E. coli

PARP11 Protein, Human, Recombinant (His)

Cat.No: TMPH-01879

Species: Human

Expression System: E. coli

ART3 Protein, Human, Recombinant (His)

Cat.No: TMPY-03386

Species: Human

Expression System: HEK293 Cells

CD157 Protein, Human, Recombinant (hFc)

Cat.No: TMPJ-00202

Species: Human

Expression System: HEK293 Cells

ARF5 Protein, Human, Recombinant (His)

Cat.No: TMPY-03868

Species: Human

Expression System: E. coli

ARF1 Protein, Human, Recombinant (GST)

Cat.No: TMPY-06637

Species: Human

Expression System: E. coli

MACROD1 Protein, Human, Recombinant (His)

Cat.No: TMPH-00907

Species: Human

Expression System: E. coli

MACROD1 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-00908

Species: Human

Expression System: Baculovirus Insect Cells

ARF1 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPY-06746

Species: Human

Expression System: E. coli

PARP9 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01944

Species: Human

Expression System: HEK293 Cells

ART4/CD297 Protein, Rat, Recombinant (His)

Cat.No: TMPY-03312

Species: Rat

Expression System: HEK293 Cells

ART4/CD297 Protein, Cynomolgus, Recombinant (hFc)

Cat.No: TMPY-03544

Species: Cynomolgus

Expression System: HEK293 Cells

PARP9 Protein, Human, Recombinant (His)

Cat.No: TMPH-01882

Species: Human

Expression System: E. coli

ARF1 Protein, Human, Recombinant (His)

Cat.No: TMPY-04130

Species: Human

Expression System: E. coli

PARP14 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01942

Species: Human

Expression System: HEK293 Cells

ART4/CD297 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPY-03777

Species: Cynomolgus

Expression System: HEK293 Cells

PARP12 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01941

Species: Human

Expression System: E. coli

CARDS Protein, Mycoplasma pneumoniae, Recombinant (His & Myc)

Cat.No: TMPH-03026

Species: Mycoplasma pneumoniae

Expression System: E. coli

SLC25A6 Protein, Human, Recombinant (His & KSI)

Cat.No: TMPH-00906

Species: Human

Expression System: E. coli

MDGA2 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01620

Species: Mouse

Expression System: HEK293 Cells

ART4/CD297 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-02822

Species: Mouse

Expression System: HEK293 Cells

Diphtheria toxin Protein, Corynephage omega, Recombinant (His & Myc)

Cat.No: TMPH-00432

Species: Corynephage omega

Expression System: E. coli

ART1 Protein, Human, Recombinant (His)

Cat.No: TMPY-06532

Species: Human

Expression System: HEK293 Cells

P2Y1 Protein, Human, Recombinant (His)

Cat.No: TMPH-01822

Species: Human

Expression System: E. coli

ART4/CD297 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-02738

Species: Mouse

Expression System: HEK293 Cells

Exotoxin A Protein, Pseudomonas aeruginosa, Recombinant (His & KSI)

Cat.No: TMPH-03168

Species: Pseudomonas aeruginosa

Expression System: E. coli

ARL2BP Protein, Human, Recombinant (His)

Cat.No: TMPY-03500

Species: Human

Expression System: E. coli

ARL6IP6 Protein, Human, Recombinant (mFc)

Cat.No: TMPY-00344

Species: Human

Expression System: HEK293 Cells

PTX S1 Protein, Bordetella pertussis, Recombinant (His)

Cat.No: TMPH-00207

Species: Bordetella pertussis

Expression System: P. pastoris (Yeast)

PARP3 Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-02421

Species: Human

Expression System: Baculovirus Insect Cells

PARP Protein, Mouse, Recombinant (His)

Cat.No: TMPY-02465

Species: Mouse

Expression System: Baculovirus Insect Cells

SIRT6 Protein, Human, Recombinant (GST)

Cat.No: TMPH-01742

Species: Human

Expression System: E. coli

NADP-ME Protein, Human, Recombinant (His)

Cat.No: TMPH-01743

Species: Human

Expression System: E. coli

Fructose 5-dehydrogenase [NADP(+)] Protein, Erwinia citreus, Recombinant (His & KSI)

Cat.No: TMPH-00553

Species: Erwinia citreus

Expression System: E. coli

CD39 Protein, Rat, Recombinant (His)

Cat.No: TMPH-03283

Species: Rat

Expression System: Baculovirus Insect Cells

CD39 Protein, Rat, Recombinant (E. coli, His)

Cat.No: TMPH-03284

Species: Rat

Expression System: E. coli

CHD1L Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-01091

Species: Human

Expression System: E. coli

Propionate kinase Protein, E. coli O6:H1, Recombinant (His & Myc)

Cat.No: TMPH-00689

Species: E. coli

Expression System: E. coli

5-oxoprolinase/OPLAH Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-00863

Species: Human

Expression System: E. coli

GCK Protein, Pyrococcus horikoshii, Recombinant (His & Myc)

Cat.No: TMPH-03194

Species: Pyrococcus horikoshii

Expression System: E. coli

PFKM Protein, Human, Recombinant (His)

Cat.No: TMPJ-00384

Species: Human

Expression System: HEK293 Cells

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Cat. No.	Product Name	Target	Signaling Pathways
T40394	Benzamide-15N Phenylamide-15N,Benzenecarboxamide-15N,NSC-3114-15N,Benzamide-15N
	Benzamide-15N (NSC-3114-15N) is a 15N-labeled Benzamide. Benzamide inhibits poly(ADP-ribose) polymerase (PARP).
T71300	Pentoxifylline-d6
	Pentoxifylline-d6 is intended for use as an internal standard for the quantification of pentoxifylline by GC- or LC-MS. Pentoxifylline is a hemorrheologic agent. It increases the deformability of washed isolated human erythrocytes when used at a concentration of 100 µM. Pentoxifylline (1, 2, and 3 mM) inhibits ADP-induced platelet aggregation in isolated human whole blood. It inhibits thrombus formation induced by ADP in a hamster cheek pouch model when administered at doses of 5, 10, and 20 mg/...

同位素标记化合物

Cat.No: T40394

Synonym: Phenylamide-15N,Benzenecarboxamide-15N,NSC-3114-15N,Benzamide-15N

Pentoxifylline-d6

Cat.No: T71300

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