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Search Results for " adhesion "
Targets Recommended: Others

192

抑制剂 & 化合物

38

天然产物

3

化合物库

454

重组蛋白

2

同位素标记化合物

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Cat. No. Product Name
L6100 天然多酚类化合物库

635 compounds
635 个天然多酚化合物的独特集合,可用于高通量、高内涵筛选;
L5400 抗心血管疾病化合物库

1408 compounds
1408 种心血管疾病相关的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选;
L3800 NF-κB 通路分子库

729 compounds
729 个 NF-κB 信号通路相关的小分子化合物的特有集合,用于高通量、高内涵筛选;

化合物库

天然多酚类化合物库
Cat.No: L6100
Compounds: 635
抗心血管疾病化合物库
Cat.No: L5400
Compounds: 1408
NF-κB 通路分子库
Cat.No: L3800
Compounds: 729
Cat. No. Product Name Target Signaling Pathways
TP1153L Fibronectin Adhesion-promoting Peptide acetate

Fibronectin Adhesion-promoting Peptide acetate(125720-21-0 free base),Heparin Binding Peptide acetate

Others Others
Fibronectin Adhesion-promoting Peptide acetate (Heparin Binding Peptide acetate)(125720-21-0 free base) 是在纤连蛋白的羧基末端肝素结合结构域中发现的肝素结合氨基酸序列之一。
TP1153 Fibronectin Adhesion-promoting Peptide

Heparin Binding Peptide

Fibronectin Adhesion-promoting Peptide (Heparin Binding Peptide) is one of the heparin-binding amino acid sequences found in the carboxy-terminal heparin-binding domain of fibronectin.
TP1152 Fibronectin Adhesion-promoting Peptide TFA

Heparin Binding Peptide TFA

Fibronectin Adhesion-promoting Peptide (Heparin Binding Peptide) is one of the heparin-binding amino acid sequences found in the carboxy-terminal heparin-binding domain of fibronectin. It promotes assembly of mesenchymal stem cell (MSC) spheroids into lar
T8536 Filastatin

Antifungal Microbiology/Virology
Filastatin 是一种长效的白色念珠菌丝状体抑制剂,具有强大的抗真菌作用。它抑制真菌与聚苯乙烯和人类细胞的粘附,从酵母到菌丝的形态转变,抑制菌丝特异性 HWP1 启动子。
T12783 RWJ 50271

Integrin Cytoskeletal Signaling
RWJ 50271 是具有口服活性的选择性LFA-1/ICAM-1相互作用抑制剂,抑制 LFA-1/ICAM-1 介导的细胞粘附,在细胞HL60中的IC50值为 5.0 μM。
T15391 Glufosinate ammonium

Others Others
Glufosinate ammonium 是谷氨酸的一种膦酸类似物,是一种除草剂,在植物细胞中转化为 PT (L-phosphinothricin) 。Glufosinate ammonium 显示出神经毒性作用。
T2254 A-205804

Integrin Cytoskeletal Signaling
A-205804 是一种选择性口服有效的先导抑制剂,抑制 E-selectin 和 ICAM-1表达,IC50分别为 20 nM 和 25 nM,可用于慢性炎症疾病的研究。
T9918 Daratumumab

达妥木单抗

Others; ADC Antibody Antibody-drug Conjugate/ADC Related; Others
Daratumumab 是一种首创的特异性抗CD38单克隆抗体。它损伤了 MM 细胞的粘附,从而增加了 MM 对蛋白酶体抑制的敏感性。它具有抗多发性骨髓瘤(MM) 的作用。
T10285 ALK inhibitor 1

FAK; IGF-1R; ALK Angiogenesis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
ALK inhibitor 1 是嘧啶类 ALK 的有效抑制剂。它是一种睾丸特异性丝氨酸/苏氨酸激酶 2 (TSSK2;IC50=31 nM) 和粘着斑激酶 (FAK;IC50=2 nM) 抑制剂。
T9973 FAK-IN-7

FAK Angiogenesis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
FAK-IN-7 有潜在的抗增殖活性,是一种 FAK 抑制剂。
T9576 AMP-945

FAK Angiogenesis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
AMP-945 是一种粘着斑激酶抑制剂。
T3041 ALK inhibitor 2

FAK; ALK Angiogenesis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
ALK inhibitor 2 是嘧啶类 ALK 的有效抑制剂。它是一种睾丸特异性丝氨酸/苏氨酸激酶 2 (TSSK2;IC50=37 nM) 和粘着斑激酶 (FAK;IC50=5 nM) 抑制剂。
T22889 KF38789

KF 38789

Others Others
KF38789 特异性的抑制P-selectin 与PSGL-1结合。它对 U937 细胞与 P-selectin 免疫球蛋白 G 嵌合蛋白 (P-selectin-Ig) 的结合具有抑制作用 (IC50:1.97 μM) 。
T3638 Leukadherin-1

Integrin; Complement System Cytoskeletal Signaling; Immunology/Inflammation
Leukadherin-1 是 CD11b/CD18 的变构激活剂,可增加 CD11b/CD18 依赖性细胞对纤维蛋白原的粘附,减少白细胞运动和跨内皮迁移,具有抗炎作用。
T2001 PF-573228

PF 573228

Apoptosis; FAK Angiogenesis; Apoptosis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
PF-573228是一种选择性的 FAK 抑制剂,对 FAK 纯化重组催化片段的 IC50值为4 nM。
T2314 PF-431396

FAK; PYK2 Angiogenesis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
PF 431396 是一种具有口服活性的 FAK (IC50:2 nM) 和 Pyk2 (IC50:11 nM)的抑制剂。
T6997 SU6656

FAK; Akt; Src Angiogenesis; Cytoskeletal Signaling; PI3K/Akt/mTOR signaling; Tyrosine Kinase/Adaptors
SU6656 是Src 家族激酶抑制剂,抑制 Src,Yes,Lyn,Fyn 的IC50分别为 280,20,130,170 nM。它还能抑制p-AKT。它可抑制FAK Y576/577、 Y925、Y861位点的磷酸化。
T5480 BI-4464

FAK; Ligands for Target Protein for PROTAC Angiogenesis; Cytoskeletal Signaling; PROTAC; Tyrosine Kinase/Adaptors
BI-4464 是一种高选择性的 ATP 竞争性 PTK2/FAK 抑制剂,IC50=17 nM。它可用于PROTAC 降解剂的 PTK2 配体。
T2281 GSK2256098

GSK 2256098,GSK-2256098,GTPL7939

Apoptosis; FAK Angiogenesis; Apoptosis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
GSK2256098 (GTPL7939) 是一种选择性FAK 激酶抑制剂,抑制胰腺癌细胞的生长和存活。
T1996 Defactinib

PF-04554878,VS-6063

FAK Angiogenesis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
Defactinib (VS-6063) 是新型的 FAK 抑制剂,能够时间和剂量依赖性的抑制 FAK 在 Tyr397 位点磷酸化。
T6177 PF-562271 besylate

PF-00562271 Besylate

FAK; PYK2; CDK Angiogenesis; Cell Cycle/Checkpoint; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
PF-562271 besylate (PF-00562271 Besylate) 是一种可逆的,有效的,ATP 竞争性的 FAK(IC50:1.5 nM)和 Pyk2 (IC50:13 nM)激酶抑制剂。
T2465 PF-562271

PF562271,PF 562271

FAK; PYK2; CDK Angiogenesis; Cell Cycle/Checkpoint; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
PF-562271 是一种可逆的,有效的,ATP 竞争性的 FAK (IC50:1.5 nM)和 Pyk2 (IC50:13 nM)激酶抑制剂。
T24730 Roslin 2 bromide

Roslin-2,Benzylhexamethylenetetramine bromide,Roslin2

FAK; p53 Angiogenesis; Apoptosis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
Roslin 2 bromide (Benzylhexamethylenetetramine bromide) 是一种 p53 再激活剂,可破坏 FAK 和 p53 的结合。 Roslin 2 bromide 具有抗癌作用。
T2609 Masitinib

AB1010,马赛替尼

Apoptosis; FAK; c-Fms; FGFR; Bcr-Abl; PDGFR; Src; c-Kit; Hck Angiogenesis; Apoptosis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
Masitinib (AB1010) 是生物口服可利用的选择性 c-Kit 抑制剂 (对于人重组c-Kit,IC50=200 nM),它还抑制PDGFRα/β(IC50s=540/800 nM),Lyn(对 LynB 的IC50=510 nM),Lck,较小程度上抑制FGFR3和FAK。它有抗增殖,促凋亡活性,且毒性低。
T0263 Chloropyramine hydrochloride

Nilfan,盐酸氯吡胺,Alergosan,Halopyramine hydrochloride

FAK; VEGFR; Histamine Receptor Angiogenesis; Cytoskeletal Signaling; GPCR/G Protein; Immunology/Inflammation; Neuroscience; Tyrosine Kinase/Adaptors
Chloropyramine hydrochloride (Alergosan) 是一种组胺受体 H1 拮抗剂,可抑制VEGFR-3和FAK 的生化功能。
T1902 BAY 11-7082

BAY 11-7821

Apoptosis; Others; IκB/IKK; DUB; Autophagy Apoptosis; Autophagy; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; NF-κB; Others; Ubiquitination
BAY 11-7082 (BAY 11-7821) 是一种 NF-κB 抑制剂,可抑制 TNFα 诱导的 IκBα 磷酸化 (IC50=10 μM)。BAY 11-7082 也是一种泛素特异性蛋白酶 USP7 和 USP21 的抑制剂 (IC50=0.19/0.96 μM)。
T2655 CEP-37440

CEP37440

FAK; ALK Angiogenesis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
CEP-37440 是一种新型的 FAK (IC50:2.3 nM) 和 ALK (IC50:120 nM) 双重抑制剂。
T21768 PF-562271 hydrochloride

PF-562271 HCl

FAK; PYK2; CDK Angiogenesis; Cell Cycle/Checkpoint; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
PF-562271 hydrochloride (PF-562271 HCl) 是一种可逆的,有效的,ATP 竞争性的 FAK (IC50:1.5 nM)和 Pyk2 (IC50:13 nM)激酶抑制剂。
T1918 NVP-TAE 226

TAE226

Apoptosis; FAK; c-Met/HGFR; PYK2; IGF-1R Angiogenesis; Apoptosis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
NVP-TAE 226 (TAE226) 是一种具有 ATP 竞争性的双重FAK 和IGF-1R 抑制剂,IC50分别为 5.5 nM、140 nM。它还抑制Pyk2、胰岛素受体,IC50分为 3.5 nM、40 nM。
T1950 PND-1186

PND1186,PND 1186,VS-4718,SR-2516

Apoptosis; FAK Angiogenesis; Apoptosis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
PND-1186 (VS-4718) 是一种高特异性的FAK 可逆抑制剂,IC50为 1.5 nM。它选择性促进肿瘤细胞凋亡。
T7119 Y15

1,2,4,5-苯四胺四盐酸盐,1,2,4,5-Benzenetetramine tetrahydrochlor,FAK Inhibitor 14

FAK Angiogenesis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
Y15 (1,2,4,5-Benzenetetramine tetrahydrochlor) 是一种特异性的粘着斑激酶抑制剂,能够降低其自身磷酸化活性,抑制癌细胞的活力,阻断肿瘤生长。
T15757 Limaprost

17α,20-dimethyl-δ2-PGE1,利马前列素,OP1206,ONO1206

PGE Synthase Immunology/Inflammation
Limaprost (17α,20-dimethyl-δ2-PGE1) 是PGE1类似物,也是口服具有活性的血管舒张剂。它能够增加血流量以及减少血小板聚集。它具有抗心绞痛的功能,可用于疼痛的缓解,以及用于研究缺血性症状。
T6966 RGD

RGD (Arg-Gly-Asp) Peptides,Arg-Gly-Asp,RGD Peptides

Integrin Cytoskeletal Signaling
RGD (RGD (Arg-Gly-Asp) Peptides) 是一种细胞粘附基序,可以模拟细胞粘附蛋白并与整合素结合。
T16266 NAMI-A

FAK; CETP Angiogenesis; Cytoskeletal Signaling; Metabolism; Tyrosine Kinase/Adaptors
NAMI-A 是一种钌基化合物,具有抗肿瘤转移的选择性活性。NAMI-A 可抑制癌细胞粘附和迁移。
T11742 K-7174

IL Receptor; TNF Apoptosis; Immunology/Inflammation
K-7174 是一种新型细胞粘附抑制剂, 抑制由 IL-1β 或 TNF-α 诱导的血管细胞粘附分子 1 (VCAM-1) 的表达。
T77665 ZINC40099027

ZINC-40099027,ZINC 40099027

FAK Angiogenesis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
ZINC40099027 是特异性黏着斑激酶 (FAK) 激活剂,通过激活黏着斑激酶促进持续性阿司匹林相关胃损伤的胃粘膜修复,通过加速FAK激酶结构域的酶活性来激活人黏着斑激酶,激活细胞 FAK 并促进肠上皮伤口闭合。
T8857 LJP-1586 HCl

LJP 1586,LJP-1586 hydrochloride,LJP-1586,LJP1586

Others Others
LJP-1586 HCl 是一种高选择性的血管粘附蛋白-1(VAP-1)抑制剂,通过减少脑出血(ICH)后粘附分子表达和免疫细胞浸润而显示出抗炎作用。
TP1759L GRGDSPC acetate

GRGDSPC,GRGDSPC acetate(91575-26-7 free base)

Others Others
GRGDSPC acetate (GRGDSPC acetate (91575-26-7 free base)) 是硫醇化细胞粘附的 7 个氨基酸肽。
TP1736L Fibrinogen-Binding Peptide fb-acetate

Fibrinogen-Binding Peptide (137235-80-4 fb-acetate)

Others Others
Fibrinogen-Binding Peptide 137235-80-4(fb-acetate) 是纤维蛋白原受体上玻连蛋白结合位点的推定肽模拟物。它结合纤维蛋白原并抑制血小板与纤维蛋白原的粘附和血小板聚集,还抑制血小板与玻连蛋白的粘附
T13783 MT-4

Others Others
MT-4 可阻断肿瘤细胞和肿瘤niche 表面的TG2/FN 复合体。 MT-4抑制卵巢癌(OC)细胞与腹膜的黏附。
T9776 TRPM4 inhibitor 8

TRP/TRPV Channel Membrane transporter/Ion channel
TRPM4 inhibitor 8 是瞬态受体电位 melastatin 4 (TRPM4) 的抑制剂,它有助于活力、迁移、细胞周期转变和粘附。
T67749 Fuzapladib

IS-741

Phospholipase Metabolism
Fuzapladib (IS-741) (IS-741)是一种磷脂酶A2抑制剂,可以抑制细胞粘附分子Mac-1的表达。fuzpladib 阻断炎症细胞表面表达的粘附分子(integrin)的激活,阻止炎症细胞粘附血管内皮细胞和浸润组织,控制胰腺炎的恶化。
T0002 Ethamsylate

Cyclonamine,Etamsylate,酚磺乙胺,Dicynene,Aglumin

Prostaglandin Receptor GPCR/G Protein; Immunology/Inflammation
Ethamsylate (Dicynene) 通常用作止血药,增加毛细血管内皮阻力和血小板粘附,抑制前列腺素的生物合成和作用。
T7566L GRGDSPK 2TFA(111119-28-9(free base))

EMD 56574

Others Others
GRGDSPK 2TFA(111119-28-9(free base)) (EMD 56574) 是一种抑制肽,用于 RGD 介导的整合素和细胞外基质分子之间的粘附。
T38343 Quercetin pentaacetate

Pentaacetylquercetin

RSV Microbiology/Virology
Quercetin pentaacetate (Pentaacetylquercetin) 具有多种生物活性,包括抗氧化、抗炎和抗癌特性。 Quercetin pentaacetate 与 RSV 相互作用并抑制病毒在细胞表面的粘附。
TP1447L1 Arg-Gly-Asp-Cys acetate

Arg-Gly-Asp-Cys acetate(109292-46-8 free base),RGDC acetate

Others Others
Arg-Gly-Asp-Cys acetate 抑制血小板聚集和纤维蛋白原结合。 Arg-Gly-Asp-Cys acetate 是纤连蛋白与细胞粘附分子的结合基序。
T21781 A-286982

Integrin Cytoskeletal Signaling
A 286982是高效的LFA-1/ICAM-1相互作用变构抑制剂,在LFA-1/ICAM-1结合和LFA-1介导的细胞粘附实验中,其IC50分别为44和35 nM。
T5321 Itaconic anhydride

Others Others
Itaconic anhydride 是一种从可再生资源中获得的生物基材料。广泛用于金属助粘剂、合成树脂改良剂、酯化剂、除草剂、杀虫剂。
T11044 Dihydromunduletone

DHM

GPR Endocrinology/Hormones; GPCR/G Protein
Dihydromunduletone (DHM) 是一种粘附 G 蛋白偶联受体 (aGPCR)拮抗剂,可做一种化学探针,对具有相似拴系激动剂的 GPR56 和 GPR114/ADGRG5 有抑制作用。
T13684 Equilin

7-Dehydroestrone

Calcium Channel Membrane transporter/Ion channel; Metabolism
Equilin (7-Dehydroestrone) 是神经营养性雌激素类固醇,具有血管扩张活性,通过 NF-κB 信号传导增加单核细胞-内皮粘附。Equilin 通过阻断Ca(2+)进入平滑肌来同样放松肠系膜动脉的阻力。

化合物

Fibronectin Adhesion-promoting Peptide acetate
Cat.No: TP1153L
Synonym: Fibronectin Adhesion-promoting Peptide acetate(125720-21-0 free base),Heparin Binding Peptide acetate
Target: Others
Fibronectin Adhesion-promoting Peptide
Cat.No: TP1153
Synonym: Heparin Binding Peptide
Target:
Fibronectin Adhesion-promoting Peptide TFA
Cat.No: TP1152
Synonym: Heparin Binding Peptide TFA
Target:
Filastatin
Cat.No: T8536
Synonym:
Target: Antifungal
RWJ 50271
Cat.No: T12783
Synonym:
Target: Integrin
Glufosinate ammonium
Cat.No: T15391
Synonym:
Target: Others
A-205804
Cat.No: T2254
Synonym:
Target: Integrin
Daratumumab
Cat.No: T9918
Synonym: 达妥木单抗
Target: Others, ADC Antibody
ALK inhibitor 1
Cat.No: T10285
Synonym:
Target: FAK, IGF-1R, ALK
FAK-IN-7
Cat.No: T9973
Synonym:
Target: FAK
AMP-945
Cat.No: T9576
Synonym:
Target: FAK
ALK inhibitor 2
Cat.No: T3041
Synonym:
Target: FAK, ALK
KF38789
Cat.No: T22889
Synonym: KF 38789
Target: Others
Leukadherin-1
Cat.No: T3638
Synonym:
Target: Integrin, Complement System
PF-573228
Cat.No: T2001
Synonym: PF 573228
Target: Apoptosis, FAK
PF-431396
Cat.No: T2314
Synonym:
Target: FAK, PYK2
SU6656
Cat.No: T6997
Synonym:
Target: FAK, Akt, Src
BI-4464
Cat.No: T5480
Synonym:
Target: FAK, Ligands for Target Protein for PROTAC
GSK2256098
Cat.No: T2281
Synonym: GSK 2256098,GSK-2256098,GTPL7939
Target: Apoptosis, FAK
Defactinib
Cat.No: T1996
Synonym: PF-04554878,VS-6063
Target: FAK
PF-562271 besylate
Cat.No: T6177
Synonym: PF-00562271 Besylate
Target: FAK, PYK2, CDK
PF-562271
Cat.No: T2465
Synonym: PF562271,PF 562271
Target: FAK, PYK2, CDK
Roslin 2 bromide
Cat.No: T24730
Synonym: Roslin-2,Benzylhexamethylenetetramine bromide,Roslin2
Target: FAK, p53
Masitinib
Cat.No: T2609
Synonym: AB1010,马赛替尼
Target: Apoptosis, FAK, c-Fms, FGFR, Bcr-Abl, PDGFR, Src, c-Kit, Hck
Chloropyramine hydrochloride
Cat.No: T0263
Synonym: Nilfan,盐酸氯吡胺,Alergosan,Halopyramine hydrochloride
Target: FAK, VEGFR, Histamine Receptor
BAY 11-7082
Cat.No: T1902
Synonym: BAY 11-7821
Target: Apoptosis, Others, IκB/IKK, DUB, Autophagy
CEP-37440
Cat.No: T2655
Synonym: CEP37440
Target: FAK, ALK
PF-562271 hydrochloride
Cat.No: T21768
Synonym: PF-562271 HCl
Target: FAK, PYK2, CDK
NVP-TAE 226
Cat.No: T1918
Synonym: TAE226
Target: Apoptosis, FAK, c-Met/HGFR, PYK2, IGF-1R
PND-1186
Cat.No: T1950
Synonym: PND1186,PND 1186,VS-4718,SR-2516
Target: Apoptosis, FAK
Y15
Cat.No: T7119
Synonym: 1,2,4,5-苯四胺四盐酸盐,1,2,4,5-Benzenetetramine tetrahydrochlor,FAK Inhibitor 14
Target: FAK
Limaprost
Cat.No: T15757
Synonym: 17α,20-dimethyl-δ2-PGE1,利马前列素,OP1206,ONO1206
Target: PGE Synthase
RGD
Cat.No: T6966
Synonym: RGD (Arg-Gly-Asp) Peptides,Arg-Gly-Asp,RGD Peptides
Target: Integrin
NAMI-A
Cat.No: T16266
Synonym:
Target: FAK, CETP
K-7174
Cat.No: T11742
Synonym:
Target: IL Receptor, TNF
ZINC40099027
Cat.No: T77665
Synonym: ZINC-40099027,ZINC 40099027
Target: FAK
LJP-1586 HCl
Cat.No: T8857
Synonym: LJP 1586,LJP-1586 hydrochloride,LJP-1586,LJP1586
Target: Others
GRGDSPC acetate
Cat.No: TP1759L
Synonym: GRGDSPC,GRGDSPC acetate(91575-26-7 free base)
Target: Others
Fibrinogen-Binding Peptide fb-acetate
Cat.No: TP1736L
Synonym: Fibrinogen-Binding Peptide (137235-80-4 fb-acetate)
Target: Others
MT-4
Cat.No: T13783
Synonym:
Target: Others
TRPM4 inhibitor 8
Cat.No: T9776
Synonym:
Target: TRP/TRPV Channel
Fuzapladib
Cat.No: T67749
Synonym: IS-741
Target: Phospholipase
Ethamsylate
Cat.No: T0002
Synonym: Cyclonamine,Etamsylate,酚磺乙胺,Dicynene,Aglumin
Target: Prostaglandin Receptor
GRGDSPK 2TFA(111119-28-9(free base))
Cat.No: T7566L
Synonym: EMD 56574
Target: Others
Quercetin pentaacetate
Cat.No: T38343
Synonym: Pentaacetylquercetin
Target: RSV
Arg-Gly-Asp-Cys acetate
Cat.No: TP1447L1
Synonym: Arg-Gly-Asp-Cys acetate(109292-46-8 free base),RGDC acetate
Target: Others
A-286982
Cat.No: T21781
Synonym:
Target: Integrin
Itaconic anhydride
Cat.No: T5321
Synonym:
Target: Others
Dihydromunduletone
Cat.No: T11044
Synonym: DHM
Target: GPR
Equilin
Cat.No: T13684
Synonym: 7-Dehydroestrone
Target: Calcium Channel
Cat. No. Product Name Target Signaling Pathways
TN1433 Batatasin III

FAK; Others; Akt Angiogenesis; Cytoskeletal Signaling; Others; PI3K/Akt/mTOR signaling; Tyrosine Kinase/Adaptors
Batatasin III 通过抑制上皮间质转化和 FAK-AKT 信号来抑制癌症迁移和侵袭,并具有抗癌活性。 Batatasin III 对整株生长有长期抑制作用,显示出抑制萌发活性。
T5S0761 Nitidine chloride

Apoptosis; ERK; FAK; p38 MAPK; NF-κB; Topoisomerase; STAT; Parasite Angiogenesis; Apoptosis; Cytoskeletal Signaling; DNA Damage/DNA Repair; JAK/STAT signaling; MAPK; Microbiology/Virology; NF-κB; Stem Cells; Tyrosine Kinase/Adaptors
Nitidine chloride 是从Zanthoxylum nitidum (Roxb) DC 中分离得到的,具有抗疟疾活性。它通过多个靶点通路,起抗癌作用,抑制STAT3、DNA 拓扑异构酶1和2A、ERK 和c-Src/FAK 相关信号通路。它通过MAPK 和NF-kB 途径抑制Lps 诱导的炎性细胞因子的产生。
T3122 Fangchinoline

Tetrandrine B,防己诺林碱,(+)-Limacine,Hanfangichin B,防己醇灵,(+)-Fangchinoline

Apoptosis; FAK; HIV Protease; Autophagy Angiogenesis; Apoptosis; Autophagy; Cytoskeletal Signaling; Microbiology/Virology; Proteases/Proteasome; Tyrosine Kinase/Adaptors
Fangchinoline (Tetrandrine B) 是从Stephaniatetrandra 中分离出来的,一种具有广泛生物学活性的天然产物。它是新型HIV-1抑制剂,通过损害 gp160 蛋白水解过程来抑制 HIV-1 复制。它靶向Focal adhesion kinase (FAK)并抑制肿瘤细胞中 FAK 介导的的信号传导途径。
T4S1796 Heterophyllin B

PI3K PI3K/Akt/mTOR signaling
Heterophyllin B 是一种活性环肽,从 Pseudostellaria heterophylla 中分离得到,可用于研究食管癌。
T3817 Darutigenol

Others Others
Darutigenol 是一种戊二萜,从Siegesbecikia orientalis L.中分离得到。
TN1441 Beta-Tocopherol

β-生育酚,BETA-生育酚

ERK; MAPK MAPK
Beta-Tocopherol 对由 phorbol 12-myristate 13-acetate (PMA) 诱导的人红白血病细胞 (HEL) 粘附有影响。
T5785 MALTOTETRAOSE

Fujioligo 450,Amylotetraose,α-1,4-Tetraglucose,麦芽四糖

TNF; Endogenous Metabolite Apoptosis; Metabolism
Maltotetraose (Fujioligo 450) 能够作为生物流体中酶联测定淀粉酶特性的底物。
T9599 3,4,5-Trimethoxybenzaldehyde

Anti-infection; Antibacterial Microbiology/Virology
3,4,5-Trimethoxybenzaldehyde 是合成各种药物,特别是治疗细菌感染的甲氧苄啶的中间体,它有抗念珠菌功效并抑制粘附和生物膜。
T67708 Thiolutin

Acetopyrrothin

Antibacterial; Antibiotic Microbiology/Virology
Thiolutin (Acetopyrrothin) 是一种内皮细胞粘附抑制剂,由链霉菌产生。 Thiolutin 具有抗生素和抗血管生成特性。 Thiolutin 可快速诱导 Hsp27 的磷酸化。
TN1068 Tricin

Others; CDK Cell Cycle/Checkpoint; Others
Tricin 是米糠中大量存在的一种天然类黄酮。它通过抑制 CDK9 来抑制HCMV 的复制。它通过上调 FAK 靶向 microRNA-7 的表达来抑制 C6 胶质瘤细胞的增殖和侵袭。
T3762 Hyaluronic acid

透明质酸,Hyaluronate,玻尿酸,hyaluronan

Others; Endogenous Metabolite Metabolism; Others
Hyaluronic acid (hyaluronan) 由玉米发酵得到,是由二糖的重复单元组成的生物聚合物,应用领域广泛。
TN1996 Nothofagin

ERK; IL Receptor; TNF Apoptosis; Immunology/Inflammation; MAPK
Nothofagin 具有抗氧化和抗血栓活性,它通过抑制高渗透性、CAMs 的表达以及白细胞的粘附和迁移具有抗炎活性,从而支持其作为血管炎症性疾病的治疗作用。
T2897 (Rac)-Shikonin

(±)-Shikonin,Alkanet extract,Anchusin,紫草素,Anchusa acid

Others Others
(Rac)-Shikonin (Anchusin) 具有抗肿瘤作用。它能够诱导坏死死亡来绕过癌症耐药性。
T3402 20(S)-Ginsenoside Rg3

20(S)-人参皂苷 Rg3,人参皂苷 Rg3,20(S)-Ginsenoside-Rg3,Rg3,20S-Ginsenoside Rg3,Ginsenoside Rg3,S-Ginsenoside Rg3

EGFR; Beta Amyloid; Potassium Channel; NF-κB; COX; Sodium Channel; Endogenous Metabolite Angiogenesis; Immunology/Inflammation; JAK/STAT signaling; Membrane transporter/Ion channel; Metabolism; Neuroscience; NF-κB; Tyrosine Kinase/Adaptors
20(S)-Ginsenoside Rg3 (Rg3) 是红参的主要成分,通过抑制肿瘤细胞的粘附和侵袭来抑制肿瘤细胞肺转移。它抑制Na+和hKv1.4通道,IC50分别为 32.2±4.5 和 32.6±2.2 μM。它还抑制Aβ,NF-κB 活性和COX-2表达,抑制人脐静脉内皮细胞的增殖并具有抗血管生成活性。
T6S1256 Ruscogenin

NOS; NF-κB; NOD-like Receptor (NLR) Immunology/Inflammation; NF-κB
Ruscogenin 是一种重要甾体皂苷元,提取自麦冬。它能够抑制 TXNIP/NLRP3炎症体激活和 MAPK 途径,改善脑缺血诱导的血脑屏障功能障碍,具有显著抗血栓、抗炎作用。
T3427 Polydatin

Piceid,虎杖苷,Polydotin Peceid

Apoptosis; Mitophagy; NF-κB; Autophagy Apoptosis; Autophagy; NF-κB
Polydatin (Piceid) 是从传统中药虎杖根中提取的一种天然产物,在多个实验模型中具有抗炎作用。它可抑制 G6PD,并诱导氧化和内质网应激。
T1257 Bestatin

Ubenimex,乌苯美司

Others; Aminopeptidase; Antibacterial; Antibiotic; LTR Immunology/Inflammation; Metabolism; Microbiology/Virology; Others
Bestatin (Ubenimex) 是 CD13 (Aminopeptidase N)/APN 和 leukotriene A4 hydrolase 抑制剂,可用于癌症研究。
T4958 (-)-Alkannin

Alkannin,左旋紫草素,紫草素,Shikonin

Apoptosis; PI3K Apoptosis; PI3K/Akt/mTOR signaling
(-)-Alkannin (Shikonin) 是从紫朱草中发现的一种天然产物,具有抗癌活性,可抑制细胞周期,诱导细胞凋亡,用作食品着色剂,在 Rho 激酶途径中可改善肝脏炎症。
T3927 Phellopterin

GABA Receptor Membrane transporter/Ion channel; Neuroscience
Phellopterin 是一种分离自P. trifoliata 中的天然产物。它能够调节 Akt 和 PKC 通路,抑制 TNF-alpha 诱导的 VCAM-1 表达,进而减少单核细胞与内皮细胞的粘附。
T4S1615 Sanggenon C

桑根酮C,桑根酮 C,Sanggenone C

NF-κB NF-κB
Sanggenon C (Sanggenone C) 是一种从桑属的根皮中分离得到的黄烷酮 Diels-Alder 加合物化合物。它可抑制NF-κB 活性,抑制 RAW264.7 细胞中诱导型一氧化氮合酶的表达,以及肿瘤坏死因子-α 刺激的细胞粘附和血管细胞粘附分子-1 的表达。 它具有抗氧化和抗炎作用,也有抑制胰脂肪酶作用。
T6S0721 Orientin

荭草苷,Lutexin,Luteolin-8-glucoside

Others Others
Orientin (Luteolin-8-glucoside) 是天然存在的生物活性类黄酮,是一种有前景的神经保护剂,具有多种生物特性,如抗炎、抗肿瘤、抗氧化、保护心脏等。它有用于神经性疼痛研究潜力。
T5S0053 Coptisine

黄连碱,Coptisin

Indoleamine 2,3-Dioxygenase (IDO) Metabolism
Coptisine (Coptisin) 是一种从黄连中分离到的生物碱,是非竞争性的IDO 抑制剂,Ki=为 5.8 μM,IC50=6.3 μM。
T37974 (S)-Coriolic acid

13(S)-HODE

Lipoxygenase; Mitochondrial Metabolism; PPAR DNA Damage/DNA Repair; Metabolism
(S)-Coriolic acid (13(S)-HODE) 是一种重要的细胞内信号剂,是亚油酸与植物和哺乳动物脂氧合酶反应生成的,在各种生物系统中参与细胞增殖和分化。(S)-Coriolic acid 在 1 μM 左右时,它能抑制肿瘤细胞与血管内皮的粘附,能下调 IRGpIIb/IIIa 受体的表达。(S)-Coriolic acid 是15-脂氧合酶 (15-LOX) 代谢产物,常作为内源性配体激活 PPARγ。(S)-Coriolic acid 诱导线粒体功能障碍 和气道上皮损伤。
T4S2326 Cornuside

7-Galloylsecologanol,7-O-Galloylsecologanol,山茱萸新苷,Comuside

ERK; p38 MAPK; NF-κB; JNK MAPK; NF-κB
Cornuside (Comuside) 是从山茱萸的果实中分离出的环烯醚萜苷,可用于炎症疾病的研究和促进血液循环。 它通过下调 MAPK 和 NF-κB 信号通路抑制肥大细胞介导的过敏反应,用于炎性过敏性疾病中的潜能。
T5768 bruceine B

TNF; Parasite Apoptosis; Microbiology/Virology
Bruceine B 是一种有效的白细胞-内皮细胞粘附抑制剂,可抑制蛋白质和核酸合成。
T26358 (-)-Agelastatin A

Others Others
(-)-Agelastatin A inhibits osteopontin-mediated adhesion, invasion, and colony formation.
TN5351 Cycloshizukaol A

Cycloshizukaol A prevents monocyte adhesion to HUVEC through the inhibition of cell adhesion molecules expression stimulated by TNF-alpha, it inhibits PMA-induced homotypic aggregation of HL-60 cells without cytotoxicity with MIC values of 0.9 microM.
T14347 Aureothricin

Antibacterial Microbiology/Virology
Aureothricin, a dithiolopyrrolone (DTP) antibiotic originally derived from Streptomyces, demonstrates a broad-spectrum of antibacterial effectiveness. Additionally, it inhibits the adhesion of human umbilical vein endothelial cells (HUVECs) to vitronectin[1].
T37055 Cytostatin

Others Others
Cytostatin is a natural antitumor inhibitor of cell adhesion to extracellular matrix, blocking adhesion of B16 melanoma cells to laminin and collagen type IV in vitro (IC50s = 1.3 and 1.4 μg/ml, respectively) and B16 cells metastatic activity in mice. It induces apoptosis of FS3 mouse fibrosarcoma cells (IC50 = 3.1 μg/ml). Cytostatin potently and selectively inhibits protein phosphatase 2A (PP2A; IC50 = 29 nM against the catalytic subunit), while having no effect against PP1, PP2B, or PP5.
TN5880 Mesuol

Mesuol has antioxidant activity, it shows very high scavenging activity against DPPH radical; it also has immunomodulatory activity, can potentiate percentage neutrophil adhesion in neutrophil adhesion test in rats and phagocytosis in carbon clearance assay. Mesuol can suppress HIV-1 replication in Jurkat T cells, it inhibits TNFα-induced HIV-1-LTR transcriptional activity by targeting the nuclear factor-κB (NF-κB) pathway.
TMA1944 Protopine hydrochloride

EGFR; cAMP Angiogenesis; GPCR/G Protein; JAK/STAT signaling; Tyrosine Kinase/Adaptors
Protopine has antiplatelet effects,which is due to inhibition on thromboxane formation and phosphoinositides breakdown and then lead to the decrease of intracellular calcium concentration.Protopine seems to inhibit the heterotypic cell adhesion between MD
T36513 Pyranonigrin A

Others Others
Pyranonigrin A is a fungal metabolite originally isolated from Aspergillus that has antioxidant activity. It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH;) free radicals in a cell-free assay (IC50 = 132.9 μM). Pyranonigrin A (10 μM) suppresses TNF-α-induced expression of vascular cell adhesion molecule 1 (VCAM-1) in human umbilical vein endothelial cells (HUVECs).
TN5011 Shizukaol B

ERK; IL Receptor; p38 MAPK; TNF; NOS; NF-κB; COX; HIV Protease; DNA/RNA Synthesis; Prostaglandin Receptor; JNK Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; GPCR/G Protein; Immunology/Inflammation; MAPK; Microbiology/Virology; Neuroscience; NF-κB; Proteases/Proteasome
Shizukaol B exerts anti-inflammatory effects in LPS-activated microglia partly by modulating JNK-AP-1 signaling pathway; it also shows significant anti-neuroinflammatory effects by inhibiting nitric-oxide (NO) production in lipopolysaccharide (LPS)-stimul
T37552 (+)-Macrosphelide A

Others Others
(+)-Macrosphelide A is a fungal metabolite originally isolated from Microsphaeropsis. It inhibits adhesion of HL-60 human leukemia cells to human umbilical vein endothelial cells (HUVECs) in a concentration-dependent manner. It also inhibits the growth of SKOV3 ovarian cancer cells in a concentration-dependent manner. (+)-Macrosphelide A inhibits the growth of Gram-positive bacteria, including B. subtilis, M. luteus, B. thuringiensis, and S. aureus (MICs = 143, 143, 57, and 57 μg/ml, respectivel...
TN3983 Ergosta-7,22-dien-3-one

NO Synthase; LTR Immunology/Inflammation
Ergosta-7,22-dien-3-one 是一种羊毛甾烷,能够从台湾灵芝的子实体中分离得到。Ergosta-7,22-dien-3-one 具有促炎特性,它能刺激一氧化氮的产生,诱导基因的表达,并诱导 J774A.1 细胞产生 TLRs、细胞因子、趋化因子和细胞粘附分子。
T79962 Aloenin aglycone

Others Others
Aloenin aglycone (compound 13) 作为一种NF-κB抑制剂,可从芦荟渗出液中提取。它在抑制TNFα引发的NF-κB转录活性方面表现显著(IC50: 18.7 μM)。当HepG2细胞经10 ng/mL TNFα处理时,以10 μM Aloenin aglycone处理能有效下调诱导型一氧化氮合酶(iNOS)及细胞间粘附分子1(ICAM-1)的基因表达。
T37911 cis-Resveratrol

顺式白藜芦醇,(Z)-Resveratrol

Others Others
Resveratrol is a potent phenolic antioxidant found in grapes, red wine, and various berries that also has antiproliferative and anti-inflammatory activity. cis-Resveratrol is the double bond isomer of trans-resveratrol, the more often studied and naturally abundant of the two resveratrol isomers. cis-Resveratrol exhibits antioxidant activity in the &#181M range similar to that observed with trans-resveratrol. It blocks production of reactive oxygen species (ROS) by inhibition of NAD(P)H oxidase ...
T36295 Echistatin TFA

Others Others
Echistatin TFA, the smallest active RGD protein belonging to the family of disintegrins that are derived from snake venoms, is a potent inhibitor of platelet aggregation. Echistatin is a potent inhibitor of bone resorption in culture. Echistatin is a potent antagonist of αIIbβ3, αvβ3 and α5β1[1][2][3][4]. [1]. J Musial, et al. Inhibition of platelet adhesion to surfaces of extracorporeal circuits by disintegrins. RGD-containing peptides from viper venoms. Circulation. 1990 Jul;82(1):261-73.[2]. ...

天然产物

Batatasin III
Cat.No: TN1433
Synonym:
Target: FAK, Others, Akt
Nitidine chloride
Cat.No: T5S0761
Synonym:
Target: Apoptosis, ERK, FAK, p38 MAPK, NF-κB, Topoisomerase, STAT, Parasite
Fangchinoline
Cat.No: T3122
Synonym: Tetrandrine B,防己诺林碱,(+)-Limacine,Hanfangichin B,防己醇灵,(+)-Fangchinoline
Target: Apoptosis, FAK, HIV Protease, Autophagy
Heterophyllin B
Cat.No: T4S1796
Synonym:
Target: PI3K
Darutigenol
Cat.No: T3817
Synonym:
Target: Others
Beta-Tocopherol
Cat.No: TN1441
Synonym: β-生育酚,BETA-生育酚
Target: ERK, MAPK
MALTOTETRAOSE
Cat.No: T5785
Synonym: Fujioligo 450,Amylotetraose,α-1,4-Tetraglucose,麦芽四糖
Target: TNF, Endogenous Metabolite
3,4,5-Trimethoxybenzaldehyde
Cat.No: T9599
Synonym:
Target: Anti-infection, Antibacterial
Thiolutin
Cat.No: T67708
Synonym: Acetopyrrothin
Target: Antibacterial, Antibiotic
Tricin
Cat.No: TN1068
Synonym:
Target: Others, CDK
Hyaluronic acid
Cat.No: T3762
Synonym: 透明质酸,Hyaluronate,玻尿酸,hyaluronan
Target: Others, Endogenous Metabolite
Nothofagin
Cat.No: TN1996
Synonym:
Target: ERK, IL Receptor, TNF
(Rac)-Shikonin
Cat.No: T2897
Synonym: (±)-Shikonin,Alkanet extract,Anchusin,紫草素,Anchusa acid
Target: Others
20(S)-Ginsenoside Rg3
Cat.No: T3402
Synonym: 20(S)-人参皂苷 Rg3,人参皂苷 Rg3,20(S)-Ginsenoside-Rg3,Rg3,20S-Ginsenoside Rg3,Ginsenoside Rg3,S-Ginsenoside Rg3
Target: EGFR, Beta Amyloid, Potassium Channel, NF-κB, COX, Sodium Channel, Endogenous Metabolite
Ruscogenin
Cat.No: T6S1256
Synonym:
Target: NOS, NF-κB, NOD-like Receptor (NLR)
Polydatin
Cat.No: T3427
Synonym: Piceid,虎杖苷,Polydotin Peceid
Target: Apoptosis, Mitophagy, NF-κB, Autophagy
Bestatin
Cat.No: T1257
Synonym: Ubenimex,乌苯美司
Target: Others, Aminopeptidase, Antibacterial, Antibiotic, LTR
(-)-Alkannin
Cat.No: T4958
Synonym: Alkannin,左旋紫草素,紫草素,Shikonin
Target: Apoptosis, PI3K
Phellopterin
Cat.No: T3927
Synonym:
Target: GABA Receptor
Sanggenon C
Cat.No: T4S1615
Synonym: 桑根酮C,桑根酮 C,Sanggenone C
Target: NF-κB
Orientin
Cat.No: T6S0721
Synonym: 荭草苷,Lutexin,Luteolin-8-glucoside
Target: Others
Coptisine
Cat.No: T5S0053
Synonym: 黄连碱,Coptisin
Target: Indoleamine 2,3-Dioxygenase (IDO)
(S)-Coriolic acid
Cat.No: T37974
Synonym: 13(S)-HODE
Target: Lipoxygenase, Mitochondrial Metabolism, PPAR
Cornuside
Cat.No: T4S2326
Synonym: 7-Galloylsecologanol,7-O-Galloylsecologanol,山茱萸新苷,Comuside
Target: ERK, p38 MAPK, NF-κB, JNK
bruceine B
Cat.No: T5768
Synonym:
Target: TNF, Parasite
(-)-Agelastatin A
Cat.No: T26358
Synonym:
Target: Others
Cycloshizukaol A
Cat.No: TN5351
Synonym:
Target:
Aureothricin
Cat.No: T14347
Synonym:
Target: Antibacterial
Cytostatin
Cat.No: T37055
Synonym:
Target: Others
Mesuol
Cat.No: TN5880
Synonym:
Target:
Protopine hydrochloride
Cat.No: TMA1944
Synonym:
Target: EGFR, cAMP
Pyranonigrin A
Cat.No: T36513
Synonym:
Target: Others
Shizukaol B
Cat.No: TN5011
Synonym:
Target: ERK, IL Receptor, p38 MAPK, TNF, NOS, NF-κB, COX, HIV Protease, DNA/RNA Synthesis, Prostaglandin Receptor, JNK
(+)-Macrosphelide A
Cat.No: T37552
Synonym:
Target: Others
Ergosta-7,22-dien-3-one
Cat.No: TN3983
Synonym:
Target: NO Synthase, LTR
Aloenin aglycone
Cat.No: T79962
Synonym:
Target: Others
cis-Resveratrol
Cat.No: T37911
Synonym: 顺式白藜芦醇,(Z)-Resveratrol
Target: Others
Echistatin TFA
Cat.No: T36295
Synonym:
Target: Others
Cat. No. Product Name Species Expression System
TMPY-03722 EpCAM/TROP1 Protein, Cynomolgus, Recombinant (His)

epithelial cell adhesion molecule

Cynomolgus HEK293 Cells
EpCAM/TROP1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.8 kDa and the accession number is XP_005576740.1.
TMPY-05017 ICAM-1/CD54 Protein, Rhesus, Recombinant (His)

intercellular adhesion molecule 1

Rhesus HEK293 Cells
ICAM-1/CD54 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.9 kDa and the accession number is Q5NKV6.
TMPY-05050 CEACAM5 Protein, Cynomolgus, Recombinant (His)

carcinoembryonic antigen-related cell adhesion mole...

Cynomolgus HEK293 Cells
CEACAM5 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 73.5 kDa and the accession number is XP_005589491.1.
TMPY-01830 VCAM-1 Protein, Mouse, Recombinant (His)

Vcam-1,CD106,vascular cell adhesion molecule 1

Mouse HEK293 Cells
VCAM-1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 75.8 kDa and the accession number is Q3UPN1.
TMPY-01578 CD166/ALCAM Protein, Human, Recombinant (His)

activated leukocyte cell adhesion molecule,CD166,ME...

Human HEK293 Cells
CD166/ALCAM Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.4 kDa and the accession number is Q13740-1.
TMPY-00981 ICAM-1/CD54 Protein, Human, Recombinant (aa 1-480,DDDDK)

CD54,ICAM-1,intercellular adhesion molecule 1,P3.58...

Human HEK293 Cells
ICAM-1/CD54 Protein, Human, Recombinant (aa 1-480,DDDDK) is expressed in HEK293 mammalian cells. The predicted molecular weight is 50.2 kDa and the accession number is A0A384MEK5.
TMPY-00480 NCAM1 Protein, Human, Recombinant (His)

neural cell adhesion molecule 1,CD56,MSK39,NCAM

Human HEK293 Cells
NCAM1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 66.1 kDa and the accession number is P13591-3.
TMPY-01647 CEACAM5 Protein, Human, Recombinant (His)

CD66e,CEA,carcinoembryonic antigen-related cell adhesion...

Human HEK293 Cells
CEACAM5 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 72.8 kDa and the accession number is A0A024R0K5.
TMPY-01349 ICAM-1/CD54 Protein, Mouse, Recombinant (His)

MALA-2,Ly-47,CD54,intercellular adhesion molecule 1...

Mouse HEK293 Cells
ICAM-1/CD54 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 51.7 kDa and the accession number is P13597-1.
TMPY-01142 ICAM-1/CD54 Protein, Human, Recombinant (His)

CD54,intercellular adhesion molecule 1,BB2,ICAM-1,P...

Human HEK293 Cells
ICAM-1/CD54 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 51 kDa and the accession number is A0A384MEK5.
TMPY-00947 VCAM-1 Protein, Human, Recombinant (hFc)

INCAM-100,CD106,VCAM-1,vascular cell adhesion molec...

Human HEK293 Cells
VCAM-1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 100.8 kDa and the accession number is P19320-1.
TMPY-05850 CEACAM6 Protein, Cynomolgus, Recombinant (His)

carcinoembryonic antigen-related cell adhesion mole...

Cynomolgus HEK293 Cells
CEACAM6 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 33.3 kDa and the accession number is XP_005589488.1.
TMPY-00970 CD31/PECAM-1 Protein, Human, Recombinant (His)

platelet/endothelial cell adhesion molecule 1,GPIIA...

Human HEK293 Cells
CD31/PECAM-1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 66 kDa and the accession number is EAW94208.1.
TMPY-00971 CEACAM6 Protein, Human, Recombinant (His)

NCA,CD66c,CEA,CEAL,carcinoembryonic antigen-related cell

Human HEK293 Cells
CEACAM6 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.6 kDa and the accession number is P40199.
TMPY-04123 CEACAM1 Protein, Human, Recombinant (His & hFc)

CEACAM‑1,carcinoembryonic antigen-related cell adhesion<...

Human HEK293 Cells
CEACAM1 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 71.4 kDa and the accession number is P13688-8.
TMPY-01850 CEACAM3 Protein, Human, Recombinant (His)

W282,W264,CEA,CD66D,CGM1,MGC119875,carcinoembryonic antigen ...

Human HEK293 Cells
CeACAM3 (CD66d), a member of carcinoembryonic antigen family, is a granulocyte-specific receptor involved in the opsonin-independent recognition of several bacterial pathogens. There are four members in this family: CD66a, CD66b, CD66c, and CD66d. Members of CEACAM family are widely expressed especially on human neutrophils, and, depending on the tissue, capable of regulating diverse functions including tumor promotion, tumor suppression, angiogenesis, and neutrophil activation. Abnormal overexp...
TMPY-01298 CADM1 Protein, Human, Recombinant (His)

Necl-2,cell adhesion molecule 1,SYNCAM,BL2,sTSLC-1,...

Human HEK293 Cells
CADM1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.5 kDa and the accession number is Q9BY67-1.
TMPY-01431 L1CAM Protein, Human, Recombinant (His)

N-CAM-L1,MASA,HSAS,L1 cell adhesion molecule,MIC5,N...

Human HEK293 Cells
L1CAM Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 125 kDa and the accession number is P32004-1.
TMPY-02744 CADM3 Protein, Rat, Recombinant (His)

cell adhesion molecule 3

Rat HEK293 Cells
CADM3 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35 kDa and the accession number is Q1WIM3.
TMPY-02745 ESAM Protein, Rat, Recombinant (hFc)

endothelial cell adhesion molecule

Rat HEK293 Cells
ESAM Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 51.2 kDa and the accession number is Q6AYD4.
TMPY-03039 JAM-B Protein, Rat, Recombinant (hFc)

junctional adhesion molecule 2

Rat HEK293 Cells
JAM-B Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50.3 kDa and the accession number is Q3MHC0.
TMPY-00534 EpCAM/TROP1 Protein, Cynomolgus, Rhesus, Recombinant

epithelial cell adhesion molecule

Cynomolgus,Rhesus HEK293 Cells
EpCAM/TROP1 Protein, Cynomolgus, Rhesus, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 28 kDa and the accession number is G7PM59.
TMPY-03003 EpCAM/TROP1 Protein, Rat, Recombinant (hFc)

epithelial cell adhesion molecule

Rat HEK293 Cells
EpCAM/TROP1 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 54.8 kDa and the accession number is O55159.
TMPY-00533 EpCAM/TROP1 Protein, Cynomolgus, Rhesus, Recombinant (hFc)

epithelial cell adhesion molecule

Cynomolgus,Rhesus HEK293 Cells
EpCAM/TROP1 Protein, Cynomolgus, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 54.1 kDa and the accession number is G7PM59.
TMPY-03040 JAM-B Protein, Rat, Recombinant (His)

junctional adhesion molecule 2

Rat HEK293 Cells
JAM-B Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24.7 kDa and the accession number is Q3MHC0.
TMPY-02017 ICAM-1/CD54 Protein, Rat, Recombinant (His)

intercellular adhesion molecule 1

Rat HEK293 Cells
ICAM-1/CD54 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 52.7 kDa and the accession number is Q00238-1.
TMPY-04039 CADM3 Protein, Rat, Recombinant (hFc)

cell adhesion molecule 3

Rat HEK293 Cells
CADM3 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 60.5 kDa and the accession number is Q1WIM3.
TMPY-05587 EpCAM/TROP1 Protein, Human, Recombinant (His & Avi), Biotinylated

HNPCC8,EGP314,KSA,KS1/4,TROP1,ESA,DIAR5,TROP-1,MIC18,EGP40,M...

Human HEK293 Cells
EpCAM/TROP1 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 30.7 kDa and the accession number is P16422.
TMPY-03520 CD166/ALCAM Protein, Cynomolgus, Recombinant (His)

activated leukocyte cell adhesion molecule

Cynomolgus HEK293 Cells
CD166/ALCAM Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.3 kDa and the accession number is G7NZQ8.
TMPY-00249 CD166/ALCAM Protein, Cynomolgus, Recombinant (hFc)

activated leukocyte cell adhesion molecule

Cynomolgus HEK293 Cells
CD166/ALCAM Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 82.9 kDa and the accession number is F7E9U2.
TMPY-00797 ESAM Protein, Human, Recombinant (hFc)

W117m,endothelial cell adhesion molecule

Human HEK293 Cells
ESAM Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50.5 kDa and the accession number is Q96AP7-1.
TMPY-02939 EpCAM/TROP1 Protein, Rat, Recombinant (His)

epithelial cell adhesion molecule

Rat HEK293 Cells
EpCAM/TROP1 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 29.2 kDa and the accession number is O55159.
TMPY-00239 ICAM-1/CD54 Protein, Rat, Recombinant (hFc)

intercellular adhesion molecule 1

Rat HEK293 Cells
ICAM-1/CD54 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 77.6 kDa and the accession number is A6JNN2.
TMPY-02936 CD166/ALCAM Protein, Rat, Recombinant (His)

activated leukocyte cell adhesion molecule

Rat HEK293 Cells
CD166/ALCAM Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.5 kDa and the accession number is O35112.
TMPY-03874 NCAM1 Protein, Rat, Recombinant (His)

neural cell adhesion molecule 1

Rat HEK293 Cells
NCAM1 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 79.2 kDa and the accession number is P13596-1.
TMPY-03912 CD166/ALCAM Protein, Rat, Recombinant (hFc)

activated leukocyte cell adhesion molecule

Rat HEK293 Cells
CD166/ALCAM Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 83.1 kDa and the accession number is O35112.
TMPY-01300 EpCAM/TROP1 Protein, Human, Recombinant (His)

TROP-1,ESA,EGP40,HNPCC8,EGP314,M4S1,epithelial cell adhe...

Human HEK293 Cells
EpCAM/TROP1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.84 kDa and the accession number is P16422.
TMPY-00798 ESAM Protein, Human, Recombinant

endothelial cell adhesion molecule,W117m

Human HEK293 Cells
ESAM Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 24.5 kDa and the accession number is Q96AP7-1.
TMPY-01312 ESAM Protein, Human, Recombinant (His)

endothelial cell adhesion molecule,W117m

Human HEK293 Cells
ESAM Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.4 kDa and the accession number is Q96AP7-1.
TMPY-00826 ICAM-2/CD102 Protein, Human, Recombinant (His & hFc)

CD102,intercellular adhesion molecule 2

Human HEK293 Cells
ICAM-2/CD102 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 50.3 kDa and the accession number is P13598.
TMPY-04155 NCAM2 Protein, Human, Recombinant (His)

NCAM21,neural cell adhesion molecule 2

Human HEK293 Cells
NCAM2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 77.4 kDa and the accession number is O15394-1.
TMPY-01418 ICAM-2/CD102 Protein, Human, Recombinant (His)

CD102,intercellular adhesion molecule 2

Human HEK293 Cells
ICAM-2/CD102 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the accession number is P13598.
TMPY-00251 ICAM-5 Protein, Human, Recombinant (aa 1-570,hFc)

TLN,intercellular adhesion molecule 5, telencephali...

Human HEK293 Cells
ICAM-5 Protein, Human, Recombinant (aa 1-570,hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 84.9 kDa and the accession number is Q9UMF0.
TMPJ-00930 VCAM-1 Protein, Mouse, Recombinant (hFc)

Vascular cell adhesion protein 1,Vcam1

Mouse HEK293 Cells
Vascular cell adhesion molecule 1 (VCAM-1) is a cell surface protein belonging to the immunoglobulin superfamily, the protein is expressed by activated endothelial cells and certain leukocytes (such as macrophages). IL-1 beta, IL-4, TNF-alpha and IFN-gamma induced the expression of VCAM-1. The human and mouse VCAM-1 proteins share approximately 76% amino acid similarity. Mouse VCAM-1 is Important in cell-cell recognition. it appears to function in leukocyte-endothelial cell adhesion, and interac...
TMPY-00388 ICAM-5 Protein, Human, Recombinant (His)

TLCN,intercellular adhesion molecule 5, telencephal...

Human HEK293 Cells
ICAM-5 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 87.2 kDa and the accession number is Q9UMF0.
TMPY-00191 ICAM-5 Protein, Human, Recombinant (aa 1-132,hFc)

TLCN,intercellular adhesion molecule 5, telencephal...

Human HEK293 Cells
ICAM-5 Protein, Human, Recombinant (aa 1-132,hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 38.6 kDa and the accession number is Q9UMF0.
TMPY-04151 NCAM2 Protein, Human, Recombinant (hFc)

NCAM21,neural cell adhesion molecule 2

Human HEK293 Cells
NCAM2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 102.6 kDa and the accession number is O15394-1.
TMPY-06535 CEACAM5 Protein, Cynomolgus, Recombinant (hFc)

carcinoembryonic antigen-related cell adhesion mole...

Cynomolgus HEK293 Cells
CEACAM5 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 98.76 kDa and the accession number is XP_005589491.1.
TMPY-06860 CEACAM5 Protein, Cynomolgus, Recombinant (His & Avi)

carcinoembryonic antigen-related cell adhesion mole...

Cynomolgus HEK293 Cells
CEACAM5 Protein, Cynomolgus, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 75.29 kDa and the accession number is XP_005589491.1.
TMPH-02731 ICAM4 Protein, Mouse, Recombinant (His & SUMO)

Intercellular adhesion molecule 4,Icam4

Mouse E. coli
Adhesion molecule that binds to leukocyte adhesion LFA-1 protein LFA-1 (integrin alpha-L/beta-2). ICAM4 is also a ligand for alpha-4/beta-1 and alpha-V integrins. Isoform 2 may modulate binding of membrane-associated ICAM4. ICAM4 Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 39.1 kDa and the accession number is Q9ERM2.
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重组蛋白

EpCAM/TROP1 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPY-03722
Species: Cynomolgus
Expression System: HEK293 Cells
ICAM-1/CD54 Protein, Rhesus, Recombinant (His)
Cat.No: TMPY-05017
Species: Rhesus
Expression System: HEK293 Cells
CEACAM5 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPY-05050
Species: Cynomolgus
Expression System: HEK293 Cells
VCAM-1 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01830
Species: Mouse
Expression System: HEK293 Cells
CD166/ALCAM Protein, Human, Recombinant (His)
Cat.No: TMPY-01578
Species: Human
Expression System: HEK293 Cells
ICAM-1/CD54 Protein, Human, Recombinant (aa 1-480,DDDDK)
Cat.No: TMPY-00981
Species: Human
Expression System: HEK293 Cells
NCAM1 Protein, Human, Recombinant (His)
Cat.No: TMPY-00480
Species: Human
Expression System: HEK293 Cells
CEACAM5 Protein, Human, Recombinant (His)
Cat.No: TMPY-01647
Species: Human
Expression System: HEK293 Cells
ICAM-1/CD54 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01349
Species: Mouse
Expression System: HEK293 Cells
ICAM-1/CD54 Protein, Human, Recombinant (His)
Cat.No: TMPY-01142
Species: Human
Expression System: HEK293 Cells
VCAM-1 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00947
Species: Human
Expression System: HEK293 Cells
CEACAM6 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPY-05850
Species: Cynomolgus
Expression System: HEK293 Cells
CD31/PECAM-1 Protein, Human, Recombinant (His)
Cat.No: TMPY-00970
Species: Human
Expression System: HEK293 Cells
CEACAM6 Protein, Human, Recombinant (His)
Cat.No: TMPY-00971
Species: Human
Expression System: HEK293 Cells
CEACAM1 Protein, Human, Recombinant (His & hFc)
Cat.No: TMPY-04123
Species: Human
Expression System: HEK293 Cells
CEACAM3 Protein, Human, Recombinant (His)
Cat.No: TMPY-01850
Species: Human
Expression System: HEK293 Cells
CADM1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01298
Species: Human
Expression System: HEK293 Cells
L1CAM Protein, Human, Recombinant (His)
Cat.No: TMPY-01431
Species: Human
Expression System: HEK293 Cells
CADM3 Protein, Rat, Recombinant (His)
Cat.No: TMPY-02744
Species: Rat
Expression System: HEK293 Cells
ESAM Protein, Rat, Recombinant (hFc)
Cat.No: TMPY-02745
Species: Rat
Expression System: HEK293 Cells
JAM-B Protein, Rat, Recombinant (hFc)
Cat.No: TMPY-03039
Species: Rat
Expression System: HEK293 Cells
EpCAM/TROP1 Protein, Cynomolgus, Rhesus, Recombinant
Cat.No: TMPY-00534
Species: Cynomolgus,Rhesus
Expression System: HEK293 Cells
EpCAM/TROP1 Protein, Rat, Recombinant (hFc)
Cat.No: TMPY-03003
Species: Rat
Expression System: HEK293 Cells
EpCAM/TROP1 Protein, Cynomolgus, Rhesus, Recombinant (hFc)
Cat.No: TMPY-00533
Species: Cynomolgus,Rhesus
Expression System: HEK293 Cells
JAM-B Protein, Rat, Recombinant (His)
Cat.No: TMPY-03040
Species: Rat
Expression System: HEK293 Cells
ICAM-1/CD54 Protein, Rat, Recombinant (His)
Cat.No: TMPY-02017
Species: Rat
Expression System: HEK293 Cells
CADM3 Protein, Rat, Recombinant (hFc)
Cat.No: TMPY-04039
Species: Rat
Expression System: HEK293 Cells
EpCAM/TROP1 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-05587
Species: Human
Expression System: HEK293 Cells
CD166/ALCAM Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPY-03520
Species: Cynomolgus
Expression System: HEK293 Cells
CD166/ALCAM Protein, Cynomolgus, Recombinant (hFc)
Cat.No: TMPY-00249
Species: Cynomolgus
Expression System: HEK293 Cells
ESAM Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00797
Species: Human
Expression System: HEK293 Cells
EpCAM/TROP1 Protein, Rat, Recombinant (His)
Cat.No: TMPY-02939
Species: Rat
Expression System: HEK293 Cells
ICAM-1/CD54 Protein, Rat, Recombinant (hFc)
Cat.No: TMPY-00239
Species: Rat
Expression System: HEK293 Cells
CD166/ALCAM Protein, Rat, Recombinant (His)
Cat.No: TMPY-02936
Species: Rat
Expression System: HEK293 Cells
NCAM1 Protein, Rat, Recombinant (His)
Cat.No: TMPY-03874
Species: Rat
Expression System: HEK293 Cells
CD166/ALCAM Protein, Rat, Recombinant (hFc)
Cat.No: TMPY-03912
Species: Rat
Expression System: HEK293 Cells
EpCAM/TROP1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01300
Species: Human
Expression System: HEK293 Cells
ESAM Protein, Human, Recombinant
Cat.No: TMPY-00798
Species: Human
Expression System: HEK293 Cells
ESAM Protein, Human, Recombinant (His)
Cat.No: TMPY-01312
Species: Human
Expression System: HEK293 Cells
ICAM-2/CD102 Protein, Human, Recombinant (His & hFc)
Cat.No: TMPY-00826
Species: Human
Expression System: HEK293 Cells
NCAM2 Protein, Human, Recombinant (His)
Cat.No: TMPY-04155
Species: Human
Expression System: HEK293 Cells
ICAM-2/CD102 Protein, Human, Recombinant (His)
Cat.No: TMPY-01418
Species: Human
Expression System: HEK293 Cells
ICAM-5 Protein, Human, Recombinant (aa 1-570,hFc)
Cat.No: TMPY-00251
Species: Human
Expression System: HEK293 Cells
VCAM-1 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPJ-00930
Species: Mouse
Expression System: HEK293 Cells
ICAM-5 Protein, Human, Recombinant (His)
Cat.No: TMPY-00388
Species: Human
Expression System: HEK293 Cells
ICAM-5 Protein, Human, Recombinant (aa 1-132,hFc)
Cat.No: TMPY-00191
Species: Human
Expression System: HEK293 Cells
NCAM2 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-04151
Species: Human
Expression System: HEK293 Cells
CEACAM5 Protein, Cynomolgus, Recombinant (hFc)
Cat.No: TMPY-06535
Species: Cynomolgus
Expression System: HEK293 Cells
CEACAM5 Protein, Cynomolgus, Recombinant (His & Avi)
Cat.No: TMPY-06860
Species: Cynomolgus
Expression System: HEK293 Cells
ICAM4 Protein, Mouse, Recombinant (His & SUMO)
Cat.No: TMPH-02731
Species: Mouse
Expression System: E. coli
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Cat. No. Product Name Target Signaling Pathways
TMID-0262 Lidocaine-d10 (N,N-diethyl-d10)

Lidocaine-d10 (N,N-diethyl-d10) 是 Lidocaine 的氘代化合物。Lidocaine 的 CAS 号为 137-58-6。Lidocaine是一种酰胺衍生物,抑制涉及复杂电压和依赖性的钠通道,可用于研究室性心律失常。它通过调节 miR-145 表达和进一步抑制MEK/ERK和NF-κB信号通路来减少胃癌细胞的生长,迁移和侵袭。
T71981 Gliclazide-d4

Gliclazide-d4 is intended for use as an internal standard for the quantification of gliclazide by GC- or LC-MS. Gliclazide is a sulfonylurea and an inhibitor of pancreatic β-cell ATP-sensitive potassium (KATP) channels. It is selective for pancreatic β-cell over cardiac and arterial smooth muscle cell KATP channels. Gliclazide (5 μM) increases insulin-induced glucose uptake and glucose transporter 4 (GLUT4) translocation to the plasma membrane in a differentiated 3T3L1 adipocyte model of insulin...

同位素标记化合物

Lidocaine-d10 (N,N-diethyl-d10)
Cat.No: TMID-0262
Synonym:
Target:
Gliclazide-d4
Cat.No: T71981
Synonym:
Target:
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