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Search Results for " acetoacetyl-coa "

2

抑制剂 & 化合物

2

天然产物

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Cat. No. Product Name Target Signaling Pathways
T36827 Acetoacetyl Coenzyme A (sodium salt hydrate)

Acetoacetyl-CoA

Others Others
Acetoacetyl-coenzyme A (acetoacetyl-CoA) is a precursor to HMG-CoA in the isoprenoid pathway.[1],[2] It is reversibly converted to acetyl-CoA by acetoacetyl-CoA thiolase in the mitochondria. Acetoacetyl-CoA thiolase (T2) deficiency results in a build-up of ketone bodies leading to intermittent ketoacidosis.[3],[4] Acetoacetyl-CoA is also an intermediate in the microbial biosynthesis of polyhydroxybutyrate.[5]
T15429 GSK2194069

Others; NADPH; Fatty Acid Synthase Metabolism; Others
GSK2194069 是 一种具有活性的脂肪酸合成酶 (FASN) 的 β-酮基还原酶 (KR)特异性抑制剂,在检测释放的 CoA 的试验中测的 IC50 为7.7 nM。GSK2194069 通过作用于乙酰乙酰辅酶 A 和 NADPH 来抑制 FAS 的癌细胞增殖。

化合物

Acetoacetyl Coenzyme A (sodium salt hydrate)
Cat.No: T36827
Synonym: Acetoacetyl-CoA
Target: Others
GSK2194069
Cat.No: T15429
Synonym:
Target: Others, NADPH, Fatty Acid Synthase
Cat. No. Product Name Target Signaling Pathways
T4947 3-Hydroxybutyric acid

Butanoic acid,3-羟基丁酸

Endogenous Metabolite Metabolism
3-Hydroxybutyric acid (Butanoic acid) 是一种人内源性代谢物,在 I 型糖尿病中升高。它能够调节膜脂的性质。
T40717 6-Methyluracil

Pseudothymine,6-甲基尿嘧啶

Others Others
6-Methyluracil, also known as Pseudothymine, is a metabolite derived from Uracil. It serves as an indicator for the accumulation of acetoacetyl-CoA (AACoA). Additionally, 6-Methyluracil has been observed to possess antiradiation properties in vivo.

天然产物

3-Hydroxybutyric acid
Cat.No: T4947
Synonym: Butanoic acid,3-羟基丁酸
Target: Endogenous Metabolite
6-Methyluracil
Cat.No: T40717
Synonym: Pseudothymine,6-甲基尿嘧啶
Target: Others
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