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Search Results for " abacavir "
Targets Recommended: Apoptosis HIV Protease Reverse Transcriptase

11

抑制剂 & 化合物

1

同位素标记化合物

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Cat. No. Product Name Target Signaling Pathways
T1267 Abacavir

Epzicom,Ziagen,阿巴卡韦

Apoptosis; HIV Protease; Reverse Transcriptase Apoptosis; Microbiology/Virology; Proteases/Proteasome
Abacavir (Ziagen) 是一种核苷类似物逆转录酶抑制剂。
T6367 Abacavir sulfate

Abacavir Hemisulfate,硫酸阿巴卡韦,1592U89,ABC sulfate,Ziagen

Apoptosis; HIV Protease; Reverse Transcriptase Apoptosis; Microbiology/Virology; Proteases/Proteasome
Abacavir sulfate (Ziagen) 是一种核苷类似物逆转录酶抑制剂,可用于 HIV 和 AIDS。
T36834 Abacavir Carboxylate

Others Others
Abacavir carboxylate is an inactive metabolite of the HIV-1 reverse transcriptase inhibitor abacavir . It is formed from abacavir via reactive aldehyde intermediates that can form adducts with proteins on valine residues.
T70859 ent-Abacavir

Others Others
ent-Abacavir is an enatiomer of Abacavir. Abacavir is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection. Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA. Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuroni...
T1267L Abacavir acetate

KM-133,KM133,KM 133

Others Others
Abacavir acetate (Prurisol) has the potential to be used in the treatment of plaque psoriasis.
T61679 Abacavir monosulfate

Others Others
Abacavir monosulfate is an orally active, competitive nucleoside reverse transcriptase inhibitor that effectively inhibits HIV replication. Additionally, it exhibits anticancer properties in prostate cancer cell lines, and has the ability to penetrate the blood-brain-barrier and suppress telomerase activity [1] [2] [3].
T64644 Abacavir Impurity F

Others Others
9-((1R,4S)-4-(tert-Butoxymethyl)cyclopent-2-en-1-yl)-N6-cyclopropyl-9H-purine-2,6-diamine 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T64644。
T70857 Scopadulciol

Others Others
Scopadulciol is and enzyme and proton pump inhibitor.
T9462 2-Amino-6-cyclopropylamino-9H-purine

Others Others
2-Amino-6-cyclopropylamino-9H-purine 是阿巴卡韦(abacavir) 的关键中间体,以氰基乙酸乙酯为原料,经亚硝化、盐酸胍在 EtONa 存在下环合、还原得到2,4,5-三氨基-6-羟基嘧啶
T23574 (+)-Carbovir triphosphate

LCBVTP,L CBVTP,L-CBVTP

Others Others
(+)-Carbovir triphosphate is an active metabolite of Abacavir. It was used to study the molecular mechanism of inhibition and drug resistance for HIV-1 reverse transcriptase.
T14313 Apricitabine

AVX754,SPD754

HIV Protease; DNA/RNA Synthesis Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology; Proteases/Proteasome
Apricitabine (SPD754) 是一种具有高选择性和口服活性的HIV-1逆转录酶抑制剂(Ki=0.08μM),是2′-脱氧-3′-氧-4′-硫代胞苷(dOTC)的(-)对映体 。 Apricitabine 对DNA 聚合酶α、β和γ具有抑制作用,Ki 值分别为300μM、12μM 和112.25μM。Apricitabine 在抗逆转录病毒HIV 感染者中显示出良好的抗逆转录病毒治疗效果,具有良好的耐受性和较低的选择性抗性。

化合物

Abacavir
Cat.No: T1267
Synonym: Epzicom,Ziagen,阿巴卡韦
Target: Apoptosis, HIV Protease, Reverse Transcriptase
Abacavir sulfate
Cat.No: T6367
Synonym: Abacavir Hemisulfate,硫酸阿巴卡韦,1592U89,ABC sulfate,Ziagen
Target: Apoptosis, HIV Protease, Reverse Transcriptase
Abacavir Carboxylate
Cat.No: T36834
Synonym:
Target: Others
ent-Abacavir
Cat.No: T70859
Synonym:
Target: Others
Abacavir acetate
Cat.No: T1267L
Synonym: KM-133,KM133,KM 133
Target: Others
Abacavir monosulfate
Cat.No: T61679
Synonym:
Target: Others
Abacavir Impurity F
Cat.No: T64644
Synonym:
Target: Others
Scopadulciol
Cat.No: T70857
Synonym:
Target: Others
2-Amino-6-cyclopropylamino-9H-purine
Cat.No: T9462
Synonym:
Target: Others
(+)-Carbovir triphosphate
Cat.No: T23574
Synonym: LCBVTP,L CBVTP,L-CBVTP
Target: Others
Apricitabine
Cat.No: T14313
Synonym: AVX754,SPD754
Target: HIV Protease, DNA/RNA Synthesis
Cat. No. Product Name Target Signaling Pathways
TMIJ-0217 Abacavir-d4

Abacavir-d4 是 Abacavir 的氘代化合物。Abacavir 的 CAS 号为 136470-78-5。Abacavir是一种核苷类似物逆转录酶抑制剂。

同位素标记化合物

Abacavir-d4
Cat.No: TMIJ-0217
Synonym:
Target:
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