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Search Results for " azd 1446, azd-1446, azd1446, tc 6683, tc-6683, tc6683 "
Targets Recommended: Others

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Cat. No. Product Name Target Signaling Pathways
T70785 Mefuparib Free Base

Others Others
Mefuparib Free Base is a potent, highly selective, competitive PARP1/2 inhibitor with IC50 of 3.2/1.9 nM, respectively. Mefuparib (CVL218), has been shown to have promising antiviral activity against the virus that causes COVID-19.
T70195 NL-103

Others Others
NL-103 is a novel dual-targeted inhibitor of histone deacetylases and hedgehog pathway, effectively overcomes vismodegib resistance conferred by Smo mutations. NL-103 comprises structural elements of Hh pathway inhibitor vismodegib, and histone deacetylase (HDAC) inhibitor vorinostat. NL-103 simultaneously and significantly inhibited both HDACs and Hh pathway. Importantly, NL-103 effectively overcame vismodegib resistance induced by Smoothened point mutations. Moreover, NL-103 significantly dow...

化合物

Mefuparib Free Base
Cat.No: T70785
Synonym:
Target: Others
NL-103
Cat.No: T70195
Synonym:
Target: Others
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