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Search Results for " attr "
Targets Recommended: Others

2

抑制剂 & 化合物

2

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T79417 PITB

Others Others
PITB是一种选择性且具口服活性的TTR聚集抑制剂,主要用于研究ATTR疾病。
T74645 Eplontersen

Others Others
Eplontersen 是一种三触角的、N-乙酰半乳糖胺 (GalNAc3)-缀合的反义寡核苷酸,能够靶向 甲状腺素运载蛋白 TTR 的 mRNA,抑制变体和野生型 TTR 产生。错误折叠的 TTR 诱导心脏和周围神经的淀粉样原纤维形成,并介导淀粉样 TTR (ATTR) 蛋白变性疾病。

化合物

PITB
Cat.No: T79417
Synonym:
Target: Others
Eplontersen
Cat.No: T74645
Synonym:
Target: Others
Cat. No. Product Name Species Expression System
TMPH-02242 Transthyretin Protein, Human, Recombinant (hFc & Myc)

TTR,ATTR,Transthyretin,Prealbumin,TBPA

Human HEK293 Cells
Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.
TMPK-01090 Transthyretin/Prealbumin Protein, Cynomolgus, Recombinant (His)

Prealbumin,TBPA,CTS,HEL111,Transthyretin,TTR,ATTR,C...

Cynomolgus HEK293 Cells
Transthyretin is a highly conserved homotetrameric protein, mainly synthetized by the liver and the choroid plexus of brain. The carrier role of TTR is well-known; however, many other functions have emerged, namely in the nervous system. TTR aggregates are responsible for many amyloidosis such as familial amyloidotic polyneuropathy and cardiomyopathy. Normal TTR can also aggregate and deposit in the heart of old people and in preeclampsia placental tissue.

重组蛋白

Transthyretin Protein, Human, Recombinant (hFc & Myc)
Cat.No: TMPH-02242
Species: Human
Expression System: HEK293 Cells
Transthyretin/Prealbumin Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-01090
Species: Cynomolgus
Expression System: HEK293 Cells
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