Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TQ0318L |
ARRY 520 hydrochloride
|
KSP | Cell Cycle/Checkpoint |
ARRY 520 hydrochloride 是一种驱动蛋白纺锤体蛋白 (KSP) 抑制剂。它通过凋亡诱导细胞死亡,并具有有效的抗增殖活性。 | |||
T25418 |
Filanesib TFA
Filanesib trifluoroacetic acid,ARRY-520 TFA,ARRY 520 TFA,ARRY520 TFA |
Others | Others |
Filanesib (ARRY-520) targets the kinesin spindle protein (KSP) with potential antineoplastic activity. ARRY-520 specifically inhibits KSP (kinesin-5 or Eg5), resulting in activation of the spindle assembly checkpoint, induction of cell cycle arrest during | |||
T10373 |
(R)-Filanesib
(R)-ARRY-520 |
Others | Others |
(R)-Filanesib is the R-enantiomer of ARRY-520. (R)-Filanesib is a synthetic kinesin spindle protein (KSP) inhibitor (IC50: 6 nM). | |||
TQ0318 |
Filanesib
ARRY-520,ARRY 520 |
KSP | Cell Cycle/Checkpoint |
Filanesib (ARRY 520) 是一种选择性的驱动蛋白纺锤体蛋白(KSP)的抑制剂(IC50 = 6 nM),具有强大的抗增殖活性。 |