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Search Results for " apcs "

3

抑制剂 & 化合物

1

天然产物

15

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
TP1397	QL9
	QL9 is derived from the enzyme 2-oxoglutarate dehydrogenase and belongs to the endogenous peptide repertoire of all H-2d APCs.
T78332	Eftilagimod alfa IMP321,LAG-3Ig
	Eftilagimod alfa为重组LAG-3Ig融合蛋白，具有MHC II 类分子结合能力。该药物通过介导抗原提呈细胞(APC)的激活进而激活CD8 T细胞，可用于研究转移性黑色素瘤及转移性乳腺癌。
T82517	DYSP-C34	Others	Others
	DYSP-C34是一种生物相容性强且有效的超声（US）激活多功能分子机器。它提升了亲脂性/亲水性平衡，增强了超声诱导的ROS产生，并改善了细胞渗透能力，进而显著提升了对肿瘤的靶向效果及声动力疗法（SDT）介导的肿瘤缩减能力。此外，DYSP-C34还通过激活APC展示出温和的免疫原性。

化合物

Cat.No: TP1397

Eftilagimod alfa

Cat.No: T78332

Synonym: IMP321,LAG-3Ig

Cat.No: T82517

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T38838	QS-21 Stimulon,QS-21	Others	Others
	QS-21, an immunostimulatory saponin, is a powerful vaccine adjuvant that stimulates both Th2 humoral and Th1 cell-mediated immune responses by interacting with antigen presenting cells (APCs) and T cells. Additionally, QS-21 activates the NLRP3 inflammasome, leading to the release of cytokines IL-1β and IL-18, which are dependent on caspase-1.

天然产物

Cat.No: T38838

Synonym: Stimulon,QS-21

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPK-00765	Pentraxin 2/SAP Protein, Human, Recombinant (hFc) PTX2,SAP,Pentraxin 2,MGC88159,APCS	Human	HEK293 Cells
	Pentraxin-2 (PTX-2), also known as serum amyloid P component (SAP/APCS), is a constitutive, antiinflammatory, innate immune plasma protein whose circulating level is decreased in chronic human fibrotic recombinant human PTX-2 (rhPTX-2) retards progression of chronic kidney disease in Col4a3 mutant mice with Alport syndrome, reducing blood markers of kidney failure, enhancing lifespan by 20%, and improving histological signs of disease. diseases. Pentraxin 2/SAP Protein, Human, Recombinant (hFc) ...
TMPK-00113	Pentraxin 2/SAP Protein, Mouse, Recombinant (hFc) APCS,MGC88159,SAP,Pentraxin 2,PTX2	Mouse	HEK293 Cells
	Pentraxin-2 (PTX-2), also known as serum amyloid P component (SAP/APCS), is a constitutive, antiinflammatory, innate immune plasma protein whose circulating level is decreased in chronic human fibrotic recombinant human PTX-2 (rhPTX-2) retards progression of chronic kidney disease in Col4a3 mutant mice with Alport syndrome, reducing blood markers of kidney failure, enhancing lifespan by 20%, and improving histological signs of disease. diseases. Pentraxin 2/SAP Protein, Mouse, Recombinant (hFc) ...
TMPJ-01441	OX40L/TNFSF4 Protein, Cynomolgus, Recombinant (His) OX-40L,TNFSF4,Tumor necrosis factor ligand 2B	Cynomolgus	HEK293 Cells
	Tumor necrosis factor ligand superfamily member 4(TNFSF4/OX40L) is a single-pass type II membrane protein. OX40L is expressed by DCs, macrophages and B cells and signals via its cognate receptor OX40 which is mainly expressed on APCs. OX40L/OX40 interactions are important in T-cell activation and survival and for the generation of memory T cells from activated effector T cells. It is a cytokine that binds to TNFRSF4, Co-stimulates T-cell proliferation and cytokine production. OX40L/OX40 interact...
TMPK-01177	CD28 Protein, Canine, Recombinant (mFc) CD28 molecule,CD28 antigen (Tp44),CD28,MGC138290	Canine	HEK293 Cells
	CD28 is the receptor for CD80 (B7-1) and CD86 (B7-2) proteins.When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen presenting cells (APCs). The CD86 expression on antigen presenting cells is constitutive. CD28 is the only B7 receptor constitutively expressed on naive T cells. CD28 Protein, Canine, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 41.6 kDa and the accession number is Q9GKP3.
TMPK-00653	B7-2 Protein, Cynomolgus, Recombinant (His) B72,MGC34413,LAB72,B7-2,FUN-1,B7-2 antigen,CD86,BU63,CD28LG2...	Cynomolgus	HEK293 Cells
	B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimulatory receptors, CD28 and CTLA-4, is essential for the activation and regulation of T cell immunity. B7-1 and B7-2 do not form hetero-oligomers, underscoring the biological relevance of dimeric and monomeric state of B7-1 and B7-2, respectively. B7-2 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His...
TMPK-00110	CD28 Protein, Human/Cynomolgus/Rhesus macaque, Recombinant (His & Avi) CD28 molecule,MGC138290,CD28,CD28 antigen (Tp44)	Human,Cynomolgus,Rhesus	HEK293 Cells
	CD28 is the receptor for CD80 (B7-1) and CD86 (B7-2) proteins.When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen presenting cells (APCs). The CD86 expression on antigen presenting cells is constitutive. CD28 is the only B7 receptor constitutively expressed on naive T cells. CD28 Protein, Human/Cynomolgus/Rhesus macaque, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with N-His-Avi tag. The predicted molecular weight is 18.2 kDa and the acc...
TMPK-00882	B7-2 Protein, Human, Recombinant (hFc) B7-2,FUN-1,B7-2 antigen,CD86,LAB72,CD86 molecule,CD28LG2,B70...	Human	HEK293 Cells
	B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimulatory receptors, CD28 and CTLA-4, is essential for the activation and regulation of T cell immunity. B7-1 and B7-2 do not form hetero-oligomers, underscoring the biological relevance of dimeric and monomeric state of B7-1 and B7-2, respectively. B7-2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag....
TMPK-01176	CD28 Protein, Canine, Recombinant (His) CD28 antigen (Tp44),MGC138290,CD28,CD28 molecule	Canine	HEK293 Cells
	CD28 is the receptor for CD80 (B7-1) and CD86 (B7-2) proteins.When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen presenting cells (APCs). The CD86 expression on antigen presenting cells is constitutive. CD28 is the only B7 receptor constitutively expressed on naive T cells. CD28 Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 16.7 kDa and the accession number is Q9GKP3.
TMPK-00567	VSIG4 Protein, Cynomolgus, Recombinant (His) VSIG4,CRIg,Z39IG	Cynomolgus	HEK293 Cells
	VSIG4, a B7 family-related protein, is a negative regulator of T cell activation.T cell activation by APCs is positively and negatively regulated by members of the B7 family. Unlike that of B7 family members, surface expression of VSIG4 was restricted to resting tissue macrophages and absent upon activation by LPS or in autoimmune inflammatory foci. The specific expression of VSIG4 on resting macrophages in tissue suggests that this inhibitory ligand may be important for the maintenance of T cel...
TMPK-00881	B7-2 Protein, Human, Recombinant (His & Avi), Biotinylated LAB72,B7-2,B7-2 antigen,FUN-1,CD86 molecule,MGC34413,B70,B72...	Human	HEK293 Cells
	B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimulatory receptors, CD28 and CTLA-4, is essential for the activation and regulation of T cell immunity. B7-1 and B7-2 do not form hetero-oligomers, underscoring the biological relevance of dimeric and monomeric state of B7-1 and B7-2, respectively. B7-2 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian c...
TMPK-00880	B7-2 Protein, Human, Recombinant (His & Avi) B70,B7-2 antigen,B7-2,CD86 molecule,CD86,CD28LG2,MGC34413,BU...	Human	HEK293 Cells
	B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimulatory receptors, CD28 and CTLA-4, is essential for the activation and regulation of T cell immunity. B7-1 and B7-2 do not form hetero-oligomers, underscoring the biological relevance of dimeric and monomeric state of B7-1 and B7-2, respectively. B7-2 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-Hi...
TMPK-00111	CD28 Protein, Human/Cynomolgus/Rhesus macaque, Recombinant (His & Avi), Biotinylated CD28 antigen (Tp44),CD28 molecule,CD28,MGC138290	Human,Cynomolgus,Rhesus	HEK293 Cells
	CD28 is the receptor for CD80 (B7-1) and CD86 (B7-2) proteins.When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen presenting cells (APCs). The CD86 expression on antigen presenting cells is constitutive. CD28 is the only B7 receptor constitutively expressed on naive T cells. CD28 Protein, Human/Cynomolgus/Rhesus macaque, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-His-Avi tag. The predicted molecular weight is 18.2 k...
TMPJ-00099	CD28 Protein, Mouse, Recombinant (hFc & His) T-cell-specific surface glycoprotein CD28,CD28	Mouse	HEK293 Cells
	T-cell-specific surface glycoprotein CD28, contains an Ig-like V-type domain. CD28 is one of the proteins expressed on T cells that provide co-stimulatory signals, which are required for their activation. It is the receptor for CD80 and CD86. When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen presenting cells (APCs). The CD86 expression on antigen presenting cells is constitutive. CD28 is the only B7 receptor constitutively expressed on naive T cells. It ...
TMPJ-00226	SLAMF1 Protein, Mouse, Recombinant (His) signaling lymphocytic activation molecule,SLAM family member...	Mouse	HEK293 Cells
	Signaling lymphocyte activation molecule (SLAM), is a self-ligand glycoprotein which exists not only found on the surface of activated and memory T cells, but also on the surface of activated B cells, dendritic cells, and macrophages. SLAM consists of a extracellular domain (ECD) with two Ig-like domains,transmembrane segment, and cytoplasmic domain with three immunoreceptor tyrosine switch motifs (ITSM). SLAM is thought to play an important role in adhesion between T cells and APCs and has been...
TMPY-02210	Serpin B9 Protein, Human, Recombinant (His) CAP-3,PI-9,CAP3,PI9,serpin peptidase inhibitor, clade B (ova...	Human	Baculovirus Insect Cells
	SerpinB9, also known as Cytoplasmic antiproteinase 3, CAP-3, Peptidase inhibitor 9, SERPINB9 and PI-9, is a cytoplasm protein that belongs to the serpin family and Ov-serpin subfamily. Serpin-B9 ( CAP-3 / PI-9 ) is the only known human intracellular inhibitor of granzyme B (GrB), the effector molecule in immunity against cytomegalovirus (CMV) and in renal allograft rejection. Serpin-B9 and SPI-6 expression in immune-privileged cells, APCs, and CTLs protect these cells against the actions of gran...

重组蛋白

Pentraxin 2/SAP Protein, Human, Recombinant (hFc)

Cat.No: TMPK-00765

Species: Human

Expression System: HEK293 Cells

Pentraxin 2/SAP Protein, Mouse, Recombinant (hFc)

Cat.No: TMPK-00113

Species: Mouse

Expression System: HEK293 Cells

OX40L/TNFSF4 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPJ-01441

Species: Cynomolgus

Expression System: HEK293 Cells

CD28 Protein, Canine, Recombinant (mFc)

Cat.No: TMPK-01177

Species: Canine

Expression System: HEK293 Cells

B7-2 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-00653

Species: Cynomolgus

Expression System: HEK293 Cells

CD28 Protein, Human/Cynomolgus/Rhesus macaque, Recombinant (His & Avi)

Cat.No: TMPK-00110

Species: Human,Cynomolgus,Rhesus

Expression System: HEK293 Cells

B7-2 Protein, Human, Recombinant (hFc)

Cat.No: TMPK-00882

Species: Human

Expression System: HEK293 Cells

CD28 Protein, Canine, Recombinant (His)

Cat.No: TMPK-01176

Species: Canine

Expression System: HEK293 Cells

VSIG4 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-00567

Species: Cynomolgus

Expression System: HEK293 Cells

B7-2 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00881

Species: Human

Expression System: HEK293 Cells

B7-2 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00880

Species: Human

Expression System: HEK293 Cells

CD28 Protein, Human/Cynomolgus/Rhesus macaque, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00111

Species: Human,Cynomolgus,Rhesus

Expression System: HEK293 Cells

CD28 Protein, Mouse, Recombinant (hFc & His)

Cat.No: TMPJ-00099

Species: Mouse

Expression System: HEK293 Cells

SLAMF1 Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-00226

Species: Mouse

Expression System: HEK293 Cells

Serpin B9 Protein, Human, Recombinant (His)

Cat.No: TMPY-02210

Species: Human

Expression System: Baculovirus Insect Cells

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