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Search Results for " apc/c "

Targets Recommended: APC

13

抑制剂 & 化合物

6

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T8561	Apcin	APC	Cell Cycle/Checkpoint
	Apcin 是后期促进复合物/环体 (APC/C(Cdc20)) E3 连接酶活性的有效竞争性抑制剂，可通过与 Cdc20 结合并阻止底物识别竞争性地抑制 APC/C 依赖性泛素化。它占据 WD40 结构域侧面的 D-box 结合口袋，并可以延长有丝分裂。它通过阻断有丝分裂退出并通过共同添加 Ts-Arg-OMe 协同放大而起作用。
TMAZ-0248A	Anti-C6 Monoclonal Antibody-APC
	Anti-C6 Monoclonal Antibody-APC is a biotin-conjugated humanized rabbit antibody targeting C6. Anti-C6 Monoclonal Antibody-APC can be used ELISA, FACS, IF.
TMAZ-0109A	Anti-TNFRSF10C Monoclonal Antibody-APC
	Anti-TNFRSF10C Monoclonal Antibody-APC is a biotin-conjugated humanized rabbit antibody targeting TNFRSF10C. Anti-TNFRSF10C Monoclonal Antibody-APC can be used FACS.
TMAZ-0171A	Anti-C1S Monoclonal Antibody-APC
	Anti-C1S Monoclonal Antibody-APC is a biotin-conjugated humanized rabbit antibody targeting C1S. Anti-C1S Monoclonal Antibody-APC can be used ELISA, FACS.
TMAZ-0145A	Anti-UNC5C Monoclonal Antibody-APC
	Anti-UNC5C Monoclonal Antibody-APC is a biotin-conjugated humanized rabbit antibody targeting UNC5C. Anti-UNC5C Monoclonal Antibody-APC can be used FACS.
TMAZ-0218A	Anti-C1QTNF1 Monoclonal Antibody-APC
	Anti-C1QTNF1 Monoclonal Antibody-APC is a biotin-conjugated humanized rabbit antibody targeting C1QTNF1. Anti-C1QTNF1 Monoclonal Antibody-APC can be used ELISA, FACS.
TP1628L	Activated Protein C (390-404), human acetate Activated Protein C (390-404), human acetate(146340-20-7 Free base)	APC	Cell Cycle/Checkpoint
	Activated Protein C (390-404), human acetate (Activated Protein C ) 抑制 APC 抗凝活性。
T1731	TAME hydrochloride NA-P-甲苯磺酰-L-精氨酸甲酯盐酸盐,Tos-Arg-OMe HCl,TOS-ARG-OME hydrochloride	Amino Acids and Derivatives; APC	Cell Cycle/Checkpoint; Metabolism
	TAME hydrochloride (Tos-Arg-OMe HCl) 是后期促进复合体(APC/C 或 APC)的抑制剂，可与 APC/C 结合并阻止其通过 Cdc20 和 Cdh1 活化，产生有丝分裂阻滞。它是一种 od 氨基酸衍生物。
TP1196	D-Lys(Z)-Pro-Arg-pNA Chromozym Pca
	D-Lys(Z)-Pro-Arg-pNA is a luminescent substrate of activated protein C (APC).
T6693	TAME N-[(4-甲基苯基)磺酰基]-L-精氨酸甲酯,Tosylarginine methyl ester,N-4-Tosyl-L-arginine methyl ester	APC	Cell Cycle/Checkpoint
	TAME (N-4-Tosyl-L-arginine methyl ester) 是后期促进复合体(APC/C 或 APC)的抑制剂，可与 APC/C 结合并阻止其通过 Cdc20 和 Cdh1 活化，产生有丝分裂阻滞。
TP1628	Activated Protein C (390-404), human
	Activated Protein C (390-404), human, a peptide derived from the vitamin K-dependent serine protease, effectively suppresses the anticoagulant activity of APC[1].
TP1580	Activated Protein C (390-404), human TFA
	The peptide region containing residues 390-404 in Activated Protein C (APC) is essential for anticoagulant activity and is available for interaction with antibodies or with other proteins, such as the macromolecular substrates Factors Va or VIIIa. APC reg
T82526	Drotrecogin alfa (activated)	Others	Others
	Drotrecogin alfa activated (DrotAA)为重组人活化蛋白C（APC）。该化合物能够抑制由烟雾引起的大鼠肺微血管通透性上升及促炎细胞因子IL-1β水平增加，具有抗凝血与抗炎作用，并促进纤溶过程。Drotrecogin alfa activated主要用于重症脓毒症的实验研究。

化合物

Cat.No: T8561

Target: APC

Anti-C6 Monoclonal Antibody-APC

Cat.No: TMAZ-0248A

Anti-TNFRSF10C Monoclonal Antibody-APC

Cat.No: TMAZ-0109A

Anti-C1S Monoclonal Antibody-APC

Cat.No: TMAZ-0171A

Anti-UNC5C Monoclonal Antibody-APC

Cat.No: TMAZ-0145A

Anti-C1QTNF1 Monoclonal Antibody-APC

Cat.No: TMAZ-0218A

Activated Protein C (390-404), human acetate

Cat.No: TP1628L

Synonym: Activated Protein C (390-404), human acetate(146340-20-7 Free base)

Target: APC

TAME hydrochloride

Cat.No: T1731

Synonym: NA-P-甲苯磺酰-L-精氨酸甲酯盐酸盐,Tos-Arg-OMe HCl,TOS-ARG-OME hydrochloride

Target: Amino Acids and Derivatives, APC

D-Lys(Z)-Pro-Arg-pNA

Cat.No: TP1196

Synonym: Chromozym Pca

Cat.No: T6693

Synonym: N-[(4-甲基苯基)磺酰基]-L-精氨酸甲酯,Tosylarginine methyl ester,N-4-Tosyl-L-arginine methyl ester

Target: APC

Activated Protein C (390-404), human

Cat.No: TP1628

Activated Protein C (390-404), human TFA

Cat.No: TP1580

Drotrecogin alfa (activated)

Cat.No: T82526

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-03880	Protein C Protein, Human, Recombinant (His) PROC,APC,THPH4,protein C...	Human	HEK293 Cells
	Protein C Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 51.5 kDa and the accession number is P04070.
TMPJ-00441	CDH1 Protein, Human, Recombinant (His) CDH1 protein,CDH1	Human	HEK293 Cells
	Cdh1 is one of the substrate adaptor protein of the anaphase-promoting complex (APC) in the budding yeast Saccharomyces cerevisiae. Functioning as an activator of the APC/C, Cdh1 regulates the activity and substrate specificity of this ubiquitin E3-ligase.
TMPH-02287	ZRANB1 Protein, Human, Recombinant (His & Myc) TRAF-binding domain-containing protein,Zinc	Human	E. coli
	Specifically hydrolyzes 'Lys-29'-linked and 'Lys-33'-linked diubiquitin. Also cleaves 'Lys-63'-linked chains, but with 40-fold less efficiency compared to 'Lys-29'-linked ones. Positive regulator of the Wnt signaling pathway that deubiquitinates APC protein, a negative regulator of Wnt-mediated transcription. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the stress fiber dynamics and cell migration. May also modulate TNF-alpha signaling. ZRANB1 Prot...
TMPK-01450	HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Monomer Protein, Human, MHC (His & Avi), Biotinylated KRAS1,MHC,K-RAS4B,KRAS,CFC2,K-RAS...	Human	HEK293 Cells
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01456	HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Tetramer Protein, Human, MHC (His & Avi) KRAS2,NS,MHC,C-K-RAS,KRAS1,K-RAS2A,K-RAS2B...	Human	HEK293 Cells
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01451	HLA-C 03:04&B2M&KRAS G12D (GADGVGKSAL) Monomer Protein, Human, MHC (His & Avi) NS3,K-RAS4A,K-Ras 2,NS,KRAS1,RASK2,MHC,KI-RAS,KRAS,...	Human	HEK293 Cells
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.

重组蛋白

Protein C Protein, Human, Recombinant (His)

Cat.No: TMPY-03880

Species: Human

Expression System: HEK293 Cells

CDH1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00441

Species: Human

Expression System: HEK293 Cells

ZRANB1 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-02287

Species: Human

Expression System: E. coli

HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Monomer Protein, Human, MHC (His & Avi), Biotinylated

Cat.No: TMPK-01450

Species: Human

Expression System: HEK293 Cells

HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Tetramer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01456

Species: Human

Expression System: HEK293 Cells

HLA-C 03:04&B2M&KRAS G12D (GADGVGKSAL) Monomer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01451

Species: Human

Expression System: HEK293 Cells

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