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Targets Recommended: TRP/TRPV Channel

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Cat. No. Product Name Target Signaling Pathways
T21543 AP 18

TRP/TRPV Channel Membrane transporter/Ion channel
AP-18 是选择性的 TRPA1 抑制剂。AP-18 可以抑制 50 μM 肉桂醛诱导的 TRPA1 激活,在小鼠和人中的 IC50 分别为 4.5 μM 和 3.1 μM。AP-18 可以逆转 CFA 诱导的小鼠机械性痛觉过敏。AP-18 可以浓度依赖的方式减弱 30 μM AITC 诱导的 Yo-Pro 摄取(IC50= 10.3 μM)。
T39009 CAP18 (rabbit)

CAP18 (rabbit)

CAP18 (rabbit) is a 37 amino acid antimicrobial peptide derived from rabbit granulocytes. It exhibits extensive antimicrobial activity against both Gram-positive (IC50, 130-200 nM) and Gram-negative (IC50, 20-100 nM) bacteria. Thus, CAP18 (rabbit) holds promise for the study and advancement of bacterial sepsis research.
T14297 AP1867

Others Others
AP1867 is a synthetic FKBP12F36V-directed ligand.
T18611 AP1867-2-(carboxymethoxy)

PROTAC FKBP12-binding moiety 2

Others Others
AP1867-2-(carboxymethoxy), a moiety based on the synthetic FKBP12F36V-directed ligand AP1867, connects to the CRBN ligand through a linker to generate dTAG molecules[1].
T13549 AP1867-3-(aminoethoxy)

Others Others
AP1867-3-(aminoethoxy) is a synthetic ligand for FKBP and can be used in the synthesis of PROTAC FKBP12 F36V degrader.

化合物

AP 18
Cat.No: T21543
Synonym:
Target: TRP/TRPV Channel
CAP18 (rabbit)
Cat.No: T39009
Synonym: CAP18 (rabbit)
Target:
AP1867
Cat.No: T14297
Synonym:
Target: Others
AP1867-2-(carboxymethoxy)
Cat.No: T18611
Synonym: PROTAC FKBP12-binding moiety 2
Target: Others
AP1867-3-(aminoethoxy)
Cat.No: T13549
Synonym:
Target: Others
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