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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T36535 |
SEC
|
Others | Others |
SEC activates ANXA7 GTPase through the AMPK/mTORC1/STAT3 signaling pathway. It selectively induces apoptosis in cancer cells expressing high levels of ITGB4 by promoting ITGB4 nuclear translocation [1][2]. |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPJ-00888 |
ANXA7 Protein, Human, Recombinant
Annexin A7,Annexin-7,Synexin,ANXA... |
Human | E. coli |
Annexin A7 (ANXA7) is a member of the annexin family of calcium-dependent phospholipid binding proteins. Annexin A7 has a unique, highly hydrophobic N-terminal domain and a conserved C-terminal region. The C-terminal region is composed of alternating hydrophobic and hydrophilic segments. Annexin A7 is a calcium/phospholipid-binding protein with diverse properties including voltage-sensitive calcium channel activity and promotes membrane fusion and is also involved in exocytosis. |