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Targets Recommended: Apoptosis HDAC Bcr-Abl

1

抑制剂 & 化合物

4

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T16545	Pivanex Pivalyloxymethyl butyrate,AN-9	Apoptosis; HDAC; Bcr-Abl	Angiogenesis; Apoptosis; Chromatin/Epigenetic; Cytoskeletal Signaling; DNA Damage/DNA Repair; Tyrosine Kinase/Adaptors
	Pivanex (Pivalyloxymethyl butyrate) 是丁酸的一种衍生物，是具有口服活性的 HDAC 抑制剂。Pivanex 通过下调 bcr-abl 蛋白增强凋亡。Pivanex 显示出抗转移和抗血管生成的活性。

化合物

Cat.No: T16545

Synonym: Pivalyloxymethyl butyrate,AN-9

Target: Apoptosis, HDAC, Bcr-Abl

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-01671	Human metapneumovirus (strain CAN97-83) Fusion glycoprotein F0 (His & SUMO) Fusion glycoprotein F0,F	HMPV	E. coli
	Inactive precursor that is cleaved to give rise to the mature F1 and F2 fusion glycoproteins.; Class I viral fusion protein. Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and plasma cell membrane fusion, the coiled coil regions assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The forma...
TMPH-01672	Human metapneumovirus (strain CAN97-83) Matrix protein (His & Myc) M,Matrix protein,M protein	HMPV	E. coli
	Plays a crucial role in virus assembly into filaments and budding. Early in infection, localizes in the nucleus where it may inhibit host cell transcription. Later in infection, traffics to the cytoplasm through the action of host CRM1 to associate with inclusion bodies, the site of viral transcription and replication. During virus assembly and budding, acts as a bridge between the nucleocapsid and the lipid bilayer.
TMPH-01673	Human metapneumovirus (strain CAN97-83) Matrix protein (His) M,Matrix protein,M protein	HMPV	P. pastoris (Yeast)
	Plays a crucial role in virus assembly into filaments and budding. Early in infection, localizes in the nucleus where it may inhibit host cell transcription. Later in infection, traffics to the cytoplasm through the action of host CRM1 to associate with inclusion bodies, the site of viral transcription and replication. During virus assembly and budding, acts as a bridge between the nucleocapsid and the lipid bilayer.
TMPH-01674	Human metapneumovirus (strain CAN97-83) Nucleoprotein/NP Protein (His & Myc) Nucleoprotein,N,Nucleocapsid protein	HMPV	E. coli
	Encapsidates the viral RNA genome by forming a left-handed helical nucleocapsid that protects the RNA from nucleases. RNA replication depends on the availability of soluble nucleoprotein. The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication.

重组蛋白

Human metapneumovirus (strain CAN97-83) Fusion glycoprotein F0 (His & SUMO)

Cat.No: TMPH-01671

Species: HMPV

Expression System: E. coli

Human metapneumovirus (strain CAN97-83) Matrix protein (His & Myc)

Cat.No: TMPH-01672

Species: HMPV

Expression System: E. coli

Human metapneumovirus (strain CAN97-83) Matrix protein (His)

Cat.No: TMPH-01673

Species: HMPV

Expression System: P. pastoris (Yeast)

Human metapneumovirus (strain CAN97-83) Nucleoprotein/NP Protein (His & Myc)

Cat.No: TMPH-01674

Species: HMPV

Expression System: E. coli

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