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Search Results for " al 1 "
Targets Recommended: Others

255

抑制剂 & 化合物

28

天然产物

1736

重组蛋白

9

同位素标记化合物

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Cat. No. Product Name Target Signaling Pathways
T29809 AL-1

AL 1,AL1

Others Others
AL-1 is a GLYCOINOSITOL PHOSPHOLIPID MEMBRANE ANCHOR containing ephrin found in developing tectum. It can mediate the bundling of cortical axons and repel the axonal growth of retinal ganglia axons. It exists in a variety of adult tissues of BRAIN; HEART;
T21224 (+)-Fluprostenol

Fluprostenol, (+)-,Travoprost acid,AL-5848,曲伏前列素酸

Prostaglandin Receptor GPCR/G Protein; Immunology/Inflammation
(+)-Fluprostenol (AL-5848) 是前列腺素 F2 α 的类似物,是一种前列腺素 F2α 受体 PTGFR 激动剂,可降低输卵管糖蛋白 1 (OVGP1) 的表达。
T2514 Linifanib

利尼伐尼,ABT-869,RG3635,AL-39324

Apoptosis; c-Fms; VEGFR; FLT; CSF-1R; PDGFR; c-Kit; Autophagy Angiogenesis; Apoptosis; Autophagy; Tyrosine Kinase/Adaptors
Linifanib (AL-39324) 是一种高效口服的VEGFR 和PDGFR 家族多靶点抑制剂,具有显著的抗肿瘤活性。它对无关 RTKs、可溶性酪氨酸激酶或丝氨酸/苏氨酸激酶的活性要低得多。它是特异性 miR-10b 抑制剂,阻断miR-10b 的生物合成。
T12628 (R)-MG-132

(S,R,S)-(-)-MG-132,N-[(苯基甲氧基)羰基]-L-亮氨酰-N-[(1S)-1-甲酰基-3-甲基丁基]-D-亮氨酰胺,Z-Leu-D-leu-leu-al

Proteasome Proteases/Proteasome; Ubiquitination
(R)-MG-132 (Z-Leu-D-leu-leu-al) 是一种 MG-132 的对映异构体,是一种蛋白酶体 (proteasome) 抑制剂,细胞毒性比 MG-132 弱,是一种比 MG-132 更有效的proteasome 抑制剂。
T31305 Decanal, 2-ethylidene-

2-Ethylidenedecan-1-al

Others Others
Decanal, 2-ethylidene- is a biochemical.
T31306 Decanal, 2-methylene-

2-Methylenedecanal,EINECS 244-979-4,2-Methylenedecan-1-al

Others Others
Decanal, 2-methylene- is a biochemical.
T20984 Lumogallion

荧光镓,4-Chloro-3-(2,4-dihydroxyphenylazo)-2-hydroxybenzene-1-sulfonic acid

Others Others
Lumogallion (4-Chloro-3-(2,4-dihydroxyphenylazo)-2-hydroxybenzene-1-sulfonic acid) 是一种偶氮试剂,用于测定金属离子,如研究 V、Fe 和 Al
T35610 2,5-dimethyl Celecoxib

Apoptosis; Wnt/beta-catenin; Prostaglandin Receptor Apoptosis; Cytoskeletal Signaling; GPCR/G Protein; Immunology/Inflammation; Stem Cells
2,5-dimethyl Celecoxib 是塞来昔布衍生物和微粒体前列腺素 E 合酶 1 (mPGES-1) 的靶向抑制剂,mPGES-1 是炎症介质 PGE2 合成途径中的关键酶。
T36520 COR659

Cannabinoid Receptor; GABA Receptor GPCR/G Protein; Membrane transporter/Ion channel; Neuroscience
COR659 是一种有效的 GABAB 的阳性变构调节剂。COR659具有缓解大鼠对酒精和巧克力成瘾的作用。
T36949 Niaprazine

5-HT Receptor; Adrenergic Receptor; Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Niaprazine 是有效的组胺 H1 受体拮抗剂,具有抗组胺和抗血清素活性。Niaprazine 在睡眠障碍方面有研究的价值。
T37197 5-HT1A modulator 2 hydrochloride

5-HT Receptor GPCR/G Protein; Neuroscience
5-HT1A modulator 2 hydrochloride 是 8-OH-DPAT 的一种衍生物,是5-HT1A 的调节剂,Ki 为 53 nM。
T38240 2,6-Dichlorodiphenylamine

Antibacterial Microbiology/Virology
2,6-Dichlorodiphenylamine 是双氯芬酸钠的一种结构类似物,显示出抗白色念珠菌活性。2,6-Dichlorodiphenylamine 是非选择性抗炎剂,为COX 的抑制剂,在 CHO 细胞中,对人 COX-1 和 COX-2 的IC50分别为 4 和 1.3 nM。
T37734 AMPA receptor modulator-2

GluR Neuroscience
AMPA receptor modulator-2 是 AMPA 受体的有效调节剂,在 TARPγ2 依赖性 AMPA 受体上的pIC50为 10.1
T36083 DS-7423

PI3K; mTOR PI3K/Akt/mTOR signaling
DS-7423 是PI3K 和mTOR 的有效抑制剂,抑制PI3Kα 和 mTOR 的IC50分别为15.6 nM 和 34.9 nM。DS-7423表现出抗癌活性。
T36674 DMU-212

Apoptosis; ERK Apoptosis; MAPK
DMU-212 是具有口服活性的白藜芦醇的甲基化衍生物,表现出抗分裂、抗增殖、抗氧化和促进细胞凋亡的活性。它通过诱导凋亡和激活ERK1/2蛋白阻止有丝分裂。
T35856 BMS-986176

AAK1 (AP2 associated kinase 1) Neuroscience
BMS-986176 是一种有效的AAK1 抑制剂,IC50为 2.2 nM。BMS-986176在神经退行性疾病中有研究的价值。
T36682 USP30 inhibitor 18

DUB Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Ubiquitination
USP30 inhibitor 18 是有效的USP30选择性抑制剂,IC50为 0.02 μM。它增加蛋白质泛素化并加速线粒体自噬。
T36944 Ara-G

Nucleoside Antimetabolite/Analog Cell Cycle/Checkpoint; DNA Damage/DNA Repair
Ara-G 是一种脱氧鸟苷 (GdR) 类似物和核苷类似物,可被 T 淋巴谱系细胞迅速转化为其相应的阿拉伯糖基鸟嘌呤核苷酸三磷酸 (araGTP),从而抑制 DNA 合成和对 T 淋巴母细胞的选择性体外毒性细胞系以及来自 T 细胞急性淋巴细胞白血病 (ALL) 患者的新鲜分离的白血病细胞。
T35841 5-Benzyloxygramine

Dopamine Receptor; 5-HT Receptor GPCR/G Protein; Neuroscience
5-Benzyloxygramine 是一种 N 蛋白、蛋白互作的原位稳定剂,具有抗病毒和稳定 N-NTD 蛋白的作用。它能够阻断多巴胺受体,可拮抗 5-HT 对大鼠子宫和兔耳的作用。
T38238 2'-Deoxy-2'-fluorocytidine

Nucleoside Antimetabolite/Analog; Influenza Virus Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
2'-Deoxy-2'-fluorocytidine 是一种核苷类似物,可有效抑制刚果出血热病毒的复制。2'-Deoxy-2'-fluorocytidine 与 T705 的协同作用会增强对CCHFV 复制的抵抗效力。
T38361 GSK717

IL Receptor; NOD Immunology/Inflammation; NF-κB
GSK717 是 NOD2(核苷酸结合寡聚结构域 2) 的选择性抑制剂。它抑制壁酰二肽 (MDP) 诱导的 NOD2 介导的信号转导,抑制 MDP 刺激的 HEK293/hNOD2 细胞分泌 IL-8 (IC50为 400 nM)。
T38050 CP-609754

Transferase Metabolism
CP-609754 是高效的、可逆的法尼基转移酶抑制剂,对重组人 H-Ras 和重组 K-Ras 法尼基化的 IC50分别为 0.57 ng/mL 和 46 ng/mL。CP-609754有潜在的抗癌作用。
T36968 ARN-21934

Topoisomerase DNA Damage/DNA Repair
ARN-21934 是高选择性的人拓扑异构酶 II α 抑制剂,具有血脑屏障通透性。依托泊苷抑制 DNA 松弛的IC50为120 μM,ARN-21934 抑制 DNA 松弛的IC50为 2 μM。ARN-21934具有良好的体内药代动力学特性。
T39633 Navocaftor

GLPG 3067,ABBV-3067

Others Others
Navocaftor, as a cystic fibrosis transmembrane regulator ( CFTR ), is a protein modulator (US 20200377491 Al, example 1).
T74487 AL-470

Others Others
AL-470 是一个有效的抗病毒剂,对HIV-1、HIV-2、EV-A71的EC50值分别为0.27、0.63 和 0.35 µM。
T38114 AL 8810 ethyl amide

Others Others
AL 8810 is an 11β-fluoro analog of prostaglandin F2α (PGF2α) which acts as a potent and selective antagonist at the FP receptor. AL 8810 ethyl amide is an analog of AL 8810 in which the C-1 carboxyl group has been modified to an N-ethyl amide. This modification is analogous to the PG N-ethyl amides, as typified by Bimatoprost, that have been introduced as alternative PG ocular hypotensive prodrugs. In contrast to AL 8810 which contracted the cat iris, AL 8810 ethyl amide showed no contraction ac...
T35699 Fosetyl-aluminum

Others Others
0 [1]. Fan Z, Jia S, Ding N, et al. Determination of Fosetyl-Aluminium by Ion-Pair Reversed Phase-High Performance Liquid Chromatography With Evaporative Light Scattering Detection. Se Pu. 2009;27(6):849‐851. [2]. TüRK LMEZ , et al. Activity of metalaxyl-M+mancozeb, fosetyl-Al, and phosphorous acid against Phytophthora crown and root rot of apricot and cherry caused by Phytophthora palmivora. Plant Protect. Sci., 53: 216-225.
T21752 AL 8810

Others Others
AL-8810 是 PGF2α的一种 11β- 氟类似物,对PGF2α受体(FP 受体) 具有选择性拮抗作用。
T76210 POT-4 TFA

POT-4 TFA (AL-78898A TFA),Compstatin 衍生物,有效抑制补体因子 C3 激活,适应于年龄相关黄斑变性研究。
T38113 AL 6598

Others Others
Elevated intraocular pressure (IOP) is an important risk factor in developing glaucoma. Certain prostaglandins such as PGF2α and PGD2, have been shown to reduce IOP. AL 6598 is the isopropyl ester prodrug of AL 6556, a PGD2 receptor agonist that binds to DP receptors with a Ki value of 3.2 μM and demonstrates an EC50 value of 0.80 μM in an in vitro functional assay. Designed to enhance corneal absorption, AL 6598 produces a maximum 53% drop in IOP of the ocular hypertensive monkey with a 1 μg do...
T39266 hTrkA-IN-1

Others Others
hTrkA-IN-1 is a potent and orally active inhibitor of TrkA kinase with an IC 50 of 1.3 nM, compound 2.hTrkA-IN-1 can be used for the study of inflammatory disease, such as prostatitis, pelvic, et al.
T38288 Profenofos

Others Others
Profenofos is an acetylcholinesterase-inhibiting organophosphorus pesticide on field crops, vegetables, and fruit crops [1]. [1]. Madhulika Kushwaha, et al. Kushwaha, M., et al.. Profenofos, an Acetylcholinesterase-Inhibiting Organophosphorus Pesticide: A Short Review of Its Usage, Toxicity, and Biodegradation. J Environ Qual.2016 Sep;45(5):1478-1489.
T84517 AL 8810 methyl ester

Others Others
AL 8810 methyl ester为前列腺素F(2α)类似物,充当前列腺素F(2α)受体激动剂,能够与FP受体激动剂Fluprostenol进行竞争性拮抗。AL 8810 methyl ester在细胞系中对TP、DP、EP(2)、EP(4)受体亚型不具备明显效力。
T61815 AL-GDa62

Others Others
AL-GDa62是一种潜在的治疗胃癌的合成致死疗法。该化合物对MCF10A-WT(野生型)和MCF10A-CDH1-/-(突变型)同基因乳腺上皮细胞的EC50分别为3.2 μM和2 μM。
T36380 GLP-1 (1-36) amide (human, rat) (trifluoroacetate salt)

GLP-1 amide is a peptide hormone cleaved from proglucagon in the pancreas.1,2 Mice lacking the glucagon receptor (Gcgr-/-) have approximately nine-fold higher levels of total GLP-1 amide, including GLP-1 (1-36) amide and truncated GLP-1 (7-36) amide , in pancreatic tissue compared to wild-type mice.2References1. Schjoldager, B.T., Mortensen, P.E., Christiansen, J., et al. GLP-1 (glucagon-like peptide 1) and truncated GLP-1, fragments of human proglucagon, inhibit gastric acid secretion in humans...
T37809 Alphitonin

Others Others
Alphitonin is a flavonoid that has been found in L. leptolepis wood.1 It is also a metabolic intermediate that is formed during the catabolism of quercetin by the human gut bacteria E. ramulus.2,3 |1. Chen, K., Ohmura, W., Doi, S., et al. Termite feeding deterrent from Japanese larch wood. Bioresour. Technol. 95(2), 129-134 (2004).|2. Braune, A., Gütschow, M., Engst, W., et al. Degradation of quercetin and luteolin by Eubacterium ramulus. Appl. Environ. Microbiol. 67(12), 5558-55567 (2001).|3. J...
T36995 MRT 68601 hydrochloride

Others Others
Potent TBK1 (TANK-binding kinase-1) inhibitor (IC50 = 6 nM). Inhibits the formation of autophagosomes in lung cancer cells. Newman et al (2012) TBK1 kinase addiction in lung cancer cells is mediated via autophagy of Tax1bp1/Ndp52 and non-canonical NF-κB signalling. PLoS ONE 7 e50672 PMID:23209807 |McIver et al (2012) Synthesis and structure-activity relationships of a novel series of pyrimidines as potent inhibitors of TBK1/IKKe kinases. Bioorg.Med.Chem.Lett. 22 7169 PMID:23099093
T36364 Flutax-2

Others Others
Green fluorescent taxol derivative. Used for microtubule imaging. Binds microtubules with high affinity (Ka ~ 107M-1). Excitation/emission maximum λ ~ 496/526 nm. Lillo et al (2002) Location and properties of the Tax. binding center in microtubules: a picosecond laser study with fluorescent taxoids. Biochemistry. 41 12436 PMID:12369834 |Diaz et al (2000) Molecular recognition of Tax. by microtubules. Kinetics and thermodynamics of binding of fluorescent Tax. derivatives to an exposed site. J.Bio...
T38172 RO 5263397 hydrochloride

Others Others
Potent trace amine 1 (TA1) receptor agonist (EC50 values are 0.12, 35 and 17-85 nM for mouse, rat and human receptors, respectively). Increases wakefulness and reduces REM and NREM sleep duration in wild type mice. Inhibits spontaneous locomotor activity in dopamine transport (DAT) knockout mice. Espinoza et al (2018) Biochemical and functional characterization of the trace amine-associated receptor 1 (TAAR1) agonist RO5263397. Front.Pharmacol. 9 645 PMID:29977204 |Galley et al (2015) Discovery ...
T37640 trans-2-Hexadecenoyl-L-carnitine

Others Others
trans-2-Hexadecenoyl-L-carnitine is an endogenous metabolite in urine[1]. [1]. Pengxiang She, et al. Leucine and protein metabolism in obese Zucker rats. PLoS One. 2013;8(3):e59443.
T37887 1-Heptadecanoyl-rac-glycerol

Others Others
1-Heptadecanoyl-rac-glycerol is a monoacylglycerol that contains heptadecanoic acid at the sn-1 position. It is active against the bacteria E. aerogens, E. cloacae, P. mirabilis, and S. faecalis (MIC = 78 μg/ml for all).1 1-Heptadecanoyl-rac-glycerol has been found in T. africana, I. sonorae, and wheat bran.1,2,3 |1. Kuete, V., Metuno, R., Ngameni, B., et al. Antimicrobial activity of the methanolic extracts and compounds from Treculia africana and Treculia acuminata (Moraceae). S. Afr. J. Bot. ...
T36813 Lu AE98134

Others Others
Lu AE98134, an activator of voltage-gated sodium channels, acts as a partly selective Nav1.1 channels positive modulator. Lu AE98134 also increases the activity of Nav1.2 and Nav1.5 channels but not of Nav1.4, Nav1.6 and Nav1.7 channels. Lu AE98134 can be used to analyze pathophysiological functions of the Nav1.1 channel in various central nervous system diseases, including cognitive restoring in schizophrenia, et al[1].
T38143 Elaidamide

Others Others
Elaidamide is a fatty acid amide that has been found in the cerebrospinal fluid of sleep-deprived cats.1 It inhibits rat microsomal epoxide hydrolase (mEH; Ki = 70 nM).2 Elaidamide also inhibits porcine pancreatic and human synovial phospholipase A2 (PLA2).3 In vivo, elaidamide (10 mg/animal) induces physiological sleep in rats.1References1. Cravatt, B.F., Prospero-Garcia, O., Siuzdak, G., et al. Chemical characterization of a family of brain lipids that induce sleep. Science 268(5216), 1506-150...
T37666 Trihydroxycholestanoic Acid

Trihydroxycoprostanic Acid

Others Others
Trihydroxycholestanoic acid is an intermediate in the biosynthesis of cholic acid .1 Elevated plasma levels of trihydroxycholestanoic acid have been found in patients with Zellweger syndrome, a neurological disorder characterized by mutations in PEX genes which result in defects in peroxisome formation.2,3 |1. Keane, M.H., Overmars, H., Wikander, T.M., et al. Bile acid treatment alters hepatic disease and bile acid transport in peroxisome-deficient PEX2 Zellweger mice. Hepatology 45(4), 982-997 ...
T38214 1-Deoxysphingosine (m18:1(4E))

1-Deoxysphingosine (m18:1(4E))

Others Others
1-Deoxysphingosine (m18:1(4E)) is an atypical sphingolipid that contains a double bond at the 4E native position and is formed when serine palmitoyltransferase condenses palmitoyl-CoA with alanine instead of serine during sphingolipid synthesis.1,2 Plasma levels of 1-deoxysphingosine (m18:1(4E)) are increased in patients with chronic idiopathic axonal neuropathy (CIAP) and diabetic distal symmetrical polyneuropathy (DSPN).3 |1. Steiner, R., Saied, E.M., Othman, A., et al. Elucidating the chemica...
T37107 Bz-rA Phosphoramidite

Others Others
Bz-rA Phosphoramidite is used for ribonucleotides modification[1]. [1]. Elise Malek-Adamian, et al. 4'-C-Methoxy-2'-deoxy-2'-fluoro Modified Ribonucleotides Improve Metabolic Stability and Elicit Efficient RNAi-Mediated Gene Silencing. J Am Chem Soc. 2017 Oct 18;139(41):14542-14555.
T37804 8MDP

Others Others
Potent equilibrative nucleoside transporter 1 (ENT1) inhibitor (IC50 = 0.43 nM). Inhibits hENT1 and hENT2 uptake of [H3]uridine in K562 cells and K15NTD cells respectively. Lin et al (2011) Design, synthesis, and evaluation of 2-diethanolamino-4,8-diheptamethyleneimino-2-(N-aminoethyl-N-ethanolamino)-6-(N,N-diethanolamino)pyrimido[5,4-d]pyrimidine-fluorescein conjugate (8MDP-fluor), as a novel equilibrativ Bioconjug.Chem. 22 1221 PMID:21539390 |Lin et al (2007) Synthesis, flow cytometric evaluat...
T38131 (E)-10-Hydroxynortriptyline

Others Others
(E)-10-Hydroxynortriptyline (E-10-OH-NT) is a metabolite of Nortriptyline . Nortriptyline is a tricyclic antidepressant and the main active metabolite of Amitriptyline, and is used to relieve the symptoms of depression[1]. [1]. Shimoda K, et al. The impact of CYP2C19 and CYP2D6 genotypes on metabolism of amitriptyline in Japanese psychiatric patients. J Clin Psychopharmacol. 2002 Aug;22(4):371-8. [2]. Shimoda K, et al. Dean L. Amitriptyline Therapy and CYP2D6 and CYP2C19 Genotype. Biotechnology ...
T36967 LSN3106729 hydrochloride

Others Others
LSN3106729 hydrochloride, the metabolite of Abemaciclib , is a CDK inhibitor with antitumor activity. LSN3106729 hydrochloride and a CRBN ligand have been used to design PROTAC CDK4/6 degrader[1]. [1]. Edward S. Kim, et al. Abemaciclib in Combination with Single-Agent Options in Patients with Stage IV Non-Small Cell Lung Cancer: A Phase Ib Study. [2]. Nathanael Gray, et al. Degradation of cyclin-dependent kinase 4/6 (cdk4/6) by conjugation of cdk4/6 inhibitors with e3 ligase ligand and methods o...
T38052 CRA-2059 TFA

Others Others
CRA-2059 is a highly specific and selective tryptase inhibitor, with a Ki of 620 pM for recombinant human tryptase-β (rHTβ)[1][2]. Tryptase is a trypsin-like serine protease found as a major protein component in human mast cell secretory granules. CRA-2059 has the potential for inflammatory bowel disease research[1]. [1]. Tremaine WJ, et al. Treatment of mildly to moderately active ulcerative colitis with a tryptase inhibitor (APC 2059): an open-label pilot study. Aliment Pharmacol Ther. 2002;16...

化合物

AL-1
Cat.No: T29809
Synonym: AL 1,AL1
Target: Others
(+)-Fluprostenol
Cat.No: T21224
Synonym: Fluprostenol, (+)-,Travoprost acid,AL-5848,曲伏前列素酸
Target: Prostaglandin Receptor
Linifanib
Cat.No: T2514
Synonym: 利尼伐尼,ABT-869,RG3635,AL-39324
Target: Apoptosis, c-Fms, VEGFR, FLT, CSF-1R, PDGFR, c-Kit, Autophagy
(R)-MG-132
Cat.No: T12628
Synonym: (S,R,S)-(-)-MG-132,N-[(苯基甲氧基)羰基]-L-亮氨酰-N-[(1S)-1-甲酰基-3-甲基丁基]-D-亮氨酰胺,Z-Leu-D-leu-leu-al
Target: Proteasome
Decanal, 2-ethylidene-
Cat.No: T31305
Synonym: 2-Ethylidenedecan-1-al
Target: Others
Decanal, 2-methylene-
Cat.No: T31306
Synonym: 2-Methylenedecanal,EINECS 244-979-4,2-Methylenedecan-1-al
Target: Others
Lumogallion
Cat.No: T20984
Synonym: 荧光镓,4-Chloro-3-(2,4-dihydroxyphenylazo)-2-hydroxybenzene-1-sulfonic acid
Target: Others
2,5-dimethyl Celecoxib
Cat.No: T35610
Synonym:
Target: Apoptosis, Wnt/beta-catenin, Prostaglandin Receptor
COR659
Cat.No: T36520
Synonym:
Target: Cannabinoid Receptor, GABA Receptor
Niaprazine
Cat.No: T36949
Synonym:
Target: 5-HT Receptor, Adrenergic Receptor, Histamine Receptor
5-HT1A modulator 2 hydrochloride
Cat.No: T37197
Synonym:
Target: 5-HT Receptor
2,6-Dichlorodiphenylamine
Cat.No: T38240
Synonym:
Target: Antibacterial
AMPA receptor modulator-2
Cat.No: T37734
Synonym:
Target: GluR
DS-7423
Cat.No: T36083
Synonym:
Target: PI3K, mTOR
DMU-212
Cat.No: T36674
Synonym:
Target: Apoptosis, ERK
BMS-986176
Cat.No: T35856
Synonym:
Target: AAK1 (AP2 associated kinase 1)
USP30 inhibitor 18
Cat.No: T36682
Synonym:
Target: DUB
Ara-G
Cat.No: T36944
Synonym:
Target: Nucleoside Antimetabolite/Analog
5-Benzyloxygramine
Cat.No: T35841
Synonym:
Target: Dopamine Receptor, 5-HT Receptor
2'-Deoxy-2'-fluorocytidine
Cat.No: T38238
Synonym:
Target: Nucleoside Antimetabolite/Analog, Influenza Virus
GSK717
Cat.No: T38361
Synonym:
Target: IL Receptor, NOD
CP-609754
Cat.No: T38050
Synonym:
Target: Transferase
ARN-21934
Cat.No: T36968
Synonym:
Target: Topoisomerase
Navocaftor
Cat.No: T39633
Synonym: GLPG 3067,ABBV-3067
Target: Others
AL-470
Cat.No: T74487
Synonym:
Target: Others
AL 8810 ethyl amide
Cat.No: T38114
Synonym:
Target: Others
Fosetyl-aluminum
Cat.No: T35699
Synonym:
Target: Others
AL 8810
Cat.No: T21752
Synonym:
Target: Others
POT-4 TFA
Cat.No: T76210
Synonym:
Target:
AL 6598
Cat.No: T38113
Synonym:
Target: Others
hTrkA-IN-1
Cat.No: T39266
Synonym:
Target: Others
Profenofos
Cat.No: T38288
Synonym:
Target: Others
AL 8810 methyl ester
Cat.No: T84517
Synonym:
Target: Others
AL-GDa62
Cat.No: T61815
Synonym:
Target: Others
GLP-1 (1-36) amide (human, rat) (trifluoroacetate salt)
Cat.No: T36380
Synonym:
Target:
Alphitonin
Cat.No: T37809
Synonym:
Target: Others
MRT 68601 hydrochloride
Cat.No: T36995
Synonym:
Target: Others
Flutax-2
Cat.No: T36364
Synonym:
Target: Others
RO 5263397 hydrochloride
Cat.No: T38172
Synonym:
Target: Others
trans-2-Hexadecenoyl-L-carnitine
Cat.No: T37640
Synonym:
Target: Others
1-Heptadecanoyl-rac-glycerol
Cat.No: T37887
Synonym:
Target: Others
Lu AE98134
Cat.No: T36813
Synonym:
Target: Others
Elaidamide
Cat.No: T38143
Synonym:
Target: Others
Trihydroxycholestanoic Acid
Cat.No: T37666
Synonym: Trihydroxycoprostanic Acid
Target: Others
1-Deoxysphingosine (m18:1(4E))
Cat.No: T38214
Synonym: 1-Deoxysphingosine (m18:1(4E))
Target: Others
Bz-rA Phosphoramidite
Cat.No: T37107
Synonym:
Target: Others
8MDP
Cat.No: T37804
Synonym:
Target: Others
(E)-10-Hydroxynortriptyline
Cat.No: T38131
Synonym:
Target: Others
LSN3106729 hydrochloride
Cat.No: T36967
Synonym:
Target: Others
CRA-2059 TFA
Cat.No: T38052
Synonym:
Target: Others
Cat. No. Product Name Target Signaling Pathways
T9506 trans,trans-2,4-Decadienal

(2E,4E)-癸-2,4-二烯醛,trans,trans-2,4-Decadien-1-al

Others Others
trans,trans-2,4-Decadienal (trans,trans-2,4-Decadien-1-al) 是一种亚油酸的脂质过氧化产物。
T37345 5,7-Dihydroxycoumarin

Antibacterial Microbiology/Virology
5,7-Dihydroxycoumarin 是分离自Macaranga triloba 花序的香豆素,具有抗菌活性。
T37886 1-Heptadecanol

Antibacterial Microbiology/Virology
1-Heptadecanol 是分离自Solena amplexicaulis 的长链伯醇,显示出抗菌活性。
T37709 2,2,2-Trichloroethanol

Potassium Channel; Endogenous Metabolite Membrane transporter/Ion channel; Metabolism
2,2,2-Trichloroethanol 是非经典的 K2P 通道 TREK-1和 TRAAK 的激动剂。
T78484 Xanthohumol C

Others Others
Xanthohumol C,一种从Humulus lupulus的啤酒花中分离得到的异戊二烯基查尔酮。
T83391 2-Caren-10-al

2-Caren-10-al 是 C. cyminum L. 提取之精油的主要组成分子。
T83338 3β-Hydroxylanosta-8,24-dien-21-al

3β-Hydroxylanosta-8,24-dien-21-al 是一种具有肿瘤促进抑制作用的羊毛甾烷型三萜,能有效减少小鼠乳头状瘤发生的百分比。
T36295 Echistatin TFA

Others Others
Echistatin TFA, the smallest active RGD protein belonging to the family of disintegrins that are derived from snake venoms, is a potent inhibitor of platelet aggregation. Echistatin is a potent inhibitor of bone resorption in culture. Echistatin is a potent antagonist of αIIbβ3, αvβ3 and α5β1[1][2][3][4]. [1]. J Musial, et al. Inhibition of platelet adhesion to surfaces of extracorporeal circuits by disintegrins. RGD-containing peptides from viper venoms. Circulation. 1990 Jul;82(1):261-73.[2]. ...
T37962 Paeoniflorgenin

Others Others
Paeoniflorgenin is a deglucosylated metabolite of Paeoniflorin[1]. [1]. Hsiu SL, et, al. A deglucosylated metabolite of paeoniflorin of the root of Paeonia lactiflora and its pharmacokinetics in rats. Planta Med. 2003 Dec; 69(12): 1113-8.
T36000 3-Hydroxyterphenyllin

Others Others
3-Hydroxyterphenyllin is a p-terphenyl fungal metabolite originally isolated from A. candidus that has diverse biological activities, including antioxidant, antiproliferative, antibacterial, and antiviral properties.1,2,3,4 It has a 96% scavenging effect on 2,2-diphenyl-1-picrylhydrazyl radicals when used at a concentration of 100 μg/ml.2 3-Hydroxyterphenyllin inhibits the growth of HeLa cervical, A549 lung, and HepG2 liver cancer cells (IC50s = 23, 36, and 32 μM, respectively), as well as methi...
T37609 (rel)-Asperparaline A

Others Others
Aspergillimide is a fungal metabolite originally isolated from A. japonicus.1 It reduces nicotinic acetylcholine receptor (nAChR) peak and slowly-desensitizing amplitudes induced by acetylcholine in silkworm (B. mori) larval neurons (IC50s = 20.2 and 39.6 nM, respectively) but has no effect on chicken α3β4-, α4β2-, and α7-containing nAChRs.2 Dietary administration of aspergillimide A (10 μg/g of diet) induces paralysis in silkworm fourth instar larvae.1 Aspergillimide A (10 and 20 mg/kg) reduces...
T36436 Spergualin trihydrochloride

Others Others
Spergualin trihydrochloride is a natural product that first identified as an antibiotic from culture filtrates of Bacillus laterosporus BMG162-aF2[1]. Spergualin trihydrochloride derivatives likely acts as Hsp70 modulators[1]. [1]. Srikanth Patury, et al. Pharmacological Targeting of the Hsp70 Chaperone. Curr Top Med Chem. 2009;9(15):1337-51.
T37690 Phenylpyropene A

Others Others
Phenylpyropene A is a fungal metabolite originally isolated from P. griseofulvum that has enzyme inhibitory and insecticidal activities.1,2,3 It inhibits acyl-coenzyme A:cholesterol acyltransferase (ACAT; IC50 = 0.8 μM).1 Phenylpyropene A inhibits diacylglycerol acyltransferase (DGAT) in rat liver microsomes (IC50 = 78.7 μM). It induces mortality in 100% of M. persicae when used at a concentration of 5 ppm.3 |1. Kwon, O.E., Rho, M.C., Song, H.Y., et al. Phenylpyropene A and B, new inhibitors of ...
T36734 Methyl brevifolincarboxylate

Others Others
Methyl brevifolincarboxylate (Brevifolincarboxylic acid methyl ester) is a potent influenza virus PB2 cap-binding inhibitor. Methyl brevifolincarboxylate exhibits inhibitory activity against influenza virus A/Puerto Rico/8/34 (H1N1) and A/Aichi/2/68 (H3N2) with IC50s of 27.16 μM and 33.41 μM. Anti-oxidant activity[1][2]. Methyl brevifolincarboxylate exhibits significant DPPH radical scavenging activity with an IC50 value of 8.9 μM. [1]. Wu QY, et al. Chromatographic fingerprint and the simultane...
T38330 Collinin

Others Others
Collinin is a coumarin that has been found in Z. schinifolium and has diverse biological activities.1,2,3,4 It is active against drug-susceptible and -resistant strains of M. tuberculosis (MIC50s = 3.13-6.25 μg/ml).1 Collinin inhibits LPS-induced nitric oxide (NO) production (IC50 = 5.9 μM) and reduces COX-2 protein levels in RAW 264.7 cells.2 It completely inhibits aggregation of isolated rabbit platelets induced by arachidonic acid , collagen, or platelet activating factor (PAF) when used at a...
T37451 Stachybotrysin B

Others Others
Stachybotrysin B is a fungal metabolite originally isolated from S. chartarum and has antiviral and anticancer activities.1,2 It has antiviral activity against HIV in SupT1 cells (IC50 = 19.2 μM).1 Stachybotrysin B is cytotoxic to K562, HeLa, and HL-60 cells (IC50s = 21.72, 39.63, and 18.5 μM, respectively).2 |1. Zhao, J., Feng, J., Tan, Z., et al. Stachybotrysins A-G, phenylspirodrimane derivatives from the fungus Stachybotrys chartarum. J. Nat. Prod. 80(6), 1819-1826 (2017).|2. Ma, X.-h., Zhen...
T36329 Terpendole I

Others Others
Terpendole I is a fungal metabolite that has been found in A. yamanashiensis.1 It is a weak inhibitor of acyl-coenzyme A:cholesterol acyltransferase (ACAT; IC50 = 145 μM) and is active against the bacteria B. cereus and B. subtilis (MICs = 100 μg/ml for both) but not S. aureus, P. aeruginosa, or K. pneumoniae (MICs = >200 μg/ml for all) or the fungus C. albicans (MIC = 200 μg/ml).1,2 It is cytotoxic to HeLa cells with an IC50 value of 52.6 μM.3 |1. Tomoda, H., Tabata, N., Yang, D.-J., et al. Ter...
T36954 Nemorosone

Others Others
Nemorosone is a polycyclic polyprenylated acylphloroglucinol (PPAP) originally isolated from C. rosea that has antiproliferative properties.1 Nemorosone inhibits growth of NB69, Kelly, SK-N-AS, and LAN-1 neuroblastoma cells (IC50s = 3.1-6.3 μM), including several drug-resistant clones, but not MRC-5 human embryonic fibroblasts (IC50 = >40 μM).2 It increases DNA fragmentation in LAN-1 cells in a dose-dependent manner, and decreases N-Myc protein levels and phosphorylation of ERK1/2 by MEK1/2. Nem...
T36893 4-oxo Withaferin A

Others Others
4-oxo Withaferin A is a derivative of the steroidal lactone withaferin A that has anticancer activity.1 It is cytotoxic to A2780 ovarian cancer cells and carboplatin-resistant A2780 (A2780/CP70) cells (IC50s = 7.3 and <1 μM, respectively) and is 4.4-fold selective for A2780 cells over non-cancerous ARPE19 cells.References1. Perestelo, N.R., Llanos, G.G., Reyes, C.P., et al. Expanding the chemical space of withaferin A by incorporating silicon to improve its clinical potential on human ovarian ca...
T38258 Phanerosporic Acid

Others Others
Phanerosporic acid is a fungal secondary metabolite originally isolated from P. chrysosporum that has antibacterial activity against B. cereus, B. subtilis, and E. coli and antifungal activity against S. cerevisiae, A. niger, O. ulmi, U. maydis, C. cucmerinum, C. cladosporioides, and B. cinerea.1 It has been used in the synthesis of macrolide derivatives.References1. Arnone, A., Assante, G., Nasini, G., et al. Phanerosporic acid, a β-resorcylate obtained from Phanerochaete chrysosporium. Phytoch...
T36738 4′-Hydroxy-2′-methylacetophenone

Others Others
4′-Hydroxy-2′-methylacetophenone, an aroma compound of red wines, is isolated from cv. Bobal grape variety. 4′-Hydroxy-2′-methylacetophenone has ciliate toxicity. 4′-Hydroxy-2′-methylacetophenone inhibits the growth of T. pyriformis, with an IC50 of 0.65 mM[1][2]. [1]. GómezGarcía-Carpintero E, et, al. Aroma characterization of red wines from cv. Bobal grape variety grown in La Mancha region. Food Research International. 2011 Jan; 44(1): 61-70. [2]. Schüürmann G, et, al. Stepwise discrimination ...
T38038 (-)-Rasfonin

Others Others
(-)-Rasfonin is a fungal metabolite that has been found in T. terrophilus.1 It inhibits proliferation of mouse splenocytes induced by concanavalin A and LPS (IC50s = 0.7 and 0.5 μg/ml, respectively). References1. Fujimoto, H., Okamoto, Y., Sone, E., et al. Eleven new 2-pyrones from a fungi imperfecti, Trichurus terrophilus, found in a screening study guided by immunomodulatory activity. Chem. Pharm. Bull. (Tokyo) 53(8), 923-929 (2005).
T36179 Aspulvinone O

Others Others
Aspulvinone O is a fungal metabolite that has been found in P. variotti and has antioxidant and anticancer activities.1,2 It scavenges 2,2-diphenyl-1-picrylhydrazyl radicals in a cell-free assay (IC50 = 11.6 μM).1 Aspulvinone O inhibits aspartate transaminase 1 (GOT1; Kd = 3.32 μM) and is cytotoxic to PANC-1, AsPC-1, and SW1990 pancreatic cancer cells (IC50s = 20.54-26.8 μM).2 It reduces the oxygen consumption rate (OCR) and induces apoptosis in SW1990 cells. Aspulvinone O (2.5 and 5 mg/kg) redu...
T37876 Fengycin

Others Others
Fengycin is a cyclic lipopeptide used as an agricultural fungicide. Fengmycin has an anti-fungal infection effect by damaging the target’s cell membrane[1]. [1]. Sreyoshi Sur, et al. Selectivity and Mechanism of Fengycin, an Antimicrobial Lipopeptide, from Molecular Dynamics. J Phys Chem B. 2018 Mar 1;122(8):2219-2226.
T35647 4-oxo-27-TBDMS Withaferin A

Others Others
4-oxo-27-TBDMS Withaferin A is a derivative of the steroidal lactone withaferin A that has anticancer activity.1 It is cytotoxic to A2780 ovarian cancer cells (IC50 = 17 μM) but not to carboplatin-resistant A2780 (A2780/CP70) cells (IC50 = >100 μM). It is selective for A2780 cells over non-cancerous ARPE19 cells (IC50 = 1,660 μM). 4-oxo-27-TBDMS Withaferin A induces DNA fragmentation in A2780 cells.References1. Perestelo, N.R., Llanos, G.G., Reyes, C.P., et al. Expanding the chemical space of wi...
T36950 Rubrofusarin triglucoside

Others Others
Rubrofusarin triglucoside is a glycoside compound isolated from Cassia obtusifolia Linn seeds. Rubrofusarin triglucoside inhibits human monoamine oxidase A (hMAO-A) with an IC50 of 85.5 μM[1]. [1]. Pradeep Paudel, et al. Rubrofusarin as a Dual Protein Tyrosine Phosphate 1B and Human Monoamine Oxidase-A Inhibitor: An in Vitro and in Silico Study. ACS Omega. 2019 Jul 3;4(7):11621-11630.
T38036 Lumisterol

Others Others
Lumisterol (9β,10α-Ergosterol), a steroid compound, is the (9β,10α)-stereoisomer of Ergosterol. Lumisterol is a photoprotective agent against UVB-induced DNA damage and anti-proliferative activities[1]. [1]. Anyamanee Chaiprasongsuk, et al. Protective Effects of Novel Derivatives of Vitamin D 3 and Lumisterol Against UVB-induced Damage in Human Keratinocytes Involve Activation of Nrf2 and p53 Defense Mechanisms. Redox Biol. 2019 Jun;24:101206.
T35524 (1S)-Calcitriol

Others Others
(1S)-Calcitriol (1α,25-Dihydroxy-3-epi-vitamin-D3) is a natural metabolite of 1α,25-dihydroxyvitamin D3 (1α,25(OH)2D3). (1S)-Calcitriol exhibits potent vitamin D receptor (VDR)-mediated actions such as inhibition of keratinocyte growth or suppression of parathyroid hormone secretion[1]. 3‐epi‐Calcitroic acid is an end product of (1S)-Calcitriol (1α,25-Dihydroxy-3-epi-vitamin-D3; 3‐epi‐1a,25(OH)2D3) metabolism by rat CYP24A1[1]. [1]. Steve Y Rhieu, et al. Metabolic stability of 3-epi-1α,25-dihydr...

天然产物

trans,trans-2,4-Decadienal
Cat.No: T9506
Synonym: (2E,4E)-癸-2,4-二烯醛,trans,trans-2,4-Decadien-1-al
Target: Others
5,7-Dihydroxycoumarin
Cat.No: T37345
Synonym:
Target: Antibacterial
1-Heptadecanol
Cat.No: T37886
Synonym:
Target: Antibacterial
2,2,2-Trichloroethanol
Cat.No: T37709
Synonym:
Target: Potassium Channel, Endogenous Metabolite
Xanthohumol C
Cat.No: T78484
Synonym:
Target: Others
2-Caren-10-al
Cat.No: T83391
Synonym:
Target:
3β-Hydroxylanosta-8,24-dien-21-al
Cat.No: T83338
Synonym:
Target:
Echistatin TFA
Cat.No: T36295
Synonym:
Target: Others
Paeoniflorgenin
Cat.No: T37962
Synonym:
Target: Others
3-Hydroxyterphenyllin
Cat.No: T36000
Synonym:
Target: Others
(rel)-Asperparaline A
Cat.No: T37609
Synonym:
Target: Others
Spergualin trihydrochloride
Cat.No: T36436
Synonym:
Target: Others
Phenylpyropene A
Cat.No: T37690
Synonym:
Target: Others
Methyl brevifolincarboxylate
Cat.No: T36734
Synonym:
Target: Others
Collinin
Cat.No: T38330
Synonym:
Target: Others
Stachybotrysin B
Cat.No: T37451
Synonym:
Target: Others
Terpendole I
Cat.No: T36329
Synonym:
Target: Others
Nemorosone
Cat.No: T36954
Synonym:
Target: Others
4-oxo Withaferin A
Cat.No: T36893
Synonym:
Target: Others
Phanerosporic Acid
Cat.No: T38258
Synonym:
Target: Others
4′-Hydroxy-2′-methylacetophenone
Cat.No: T36738
Synonym:
Target: Others
(-)-Rasfonin
Cat.No: T38038
Synonym:
Target: Others
Aspulvinone O
Cat.No: T36179
Synonym:
Target: Others
Fengycin
Cat.No: T37876
Synonym:
Target: Others
4-oxo-27-TBDMS Withaferin A
Cat.No: T35647
Synonym:
Target: Others
Rubrofusarin triglucoside
Cat.No: T36950
Synonym:
Target: Others
Lumisterol
Cat.No: T38036
Synonym:
Target: Others
(1S)-Calcitriol
Cat.No: T35524
Synonym:
Target: Others
Cat. No. Product Name Species Expression System
TMPY-01749 Ephrin A5/EFNA5 Protein, Mouse, Recombinant (hFc)

ephrin-A5,LERK-7,EFL-5,Epl7,AL-1,RAGS,AV

Mouse HEK293 Cells
Ephrin A5/EFNA5 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48.2 kDa and the accession number is O08543-1.
TMPY-01748 Ephrin A5/EFNA5 Protein, Mouse, Recombinant (His)

Epl7,ephrin-A5,AV158822,AL-1,EFL-...

Mouse HEK293 Cells
Ephrin A5/EFNA5 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.6 kDa and the accession number is O08543-1.
TMPY-06846 HSP90 alpha Protein, Mouse, Recombinant (His)

AL024080,Hspca,hsp4,Hsp86-1,heat shock pro...

Mouse Baculovirus Insect Cells
HSP90 alpha Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 87.19 kDa and the accession number is NP_032328.2.
TMPH-01810 OR5AL1 Protein, Human, Recombinant (His)

OR5AL1,Olfactory receptor OR1...

Human E. coli
Odorant receptor. OR5AL1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 39.6 kDa and the accession number is P0C617.
TMPY-05169 Peroxiredoxin 2 Protein, Mouse, Recombinant (His)

Torin,TPx-B,Band-8,peroxiredoxin 2,PRP,AL022839,TR,...

Mouse Baculovirus Insect Cells
Peroxiredoxin 2 Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 24.1 kDa and the accession number is Q61171.
TMPJ-00331 IFNAR1 Protein, Rhesus macaque, Recombinant (His)

IFN-al,CRF2-1,IFN-alpha/beta rece...

Rhesus HEK293 Cells
Interferon‑alpha/beta receptor 1 (IFN‑ alpha / beta R1), also known as IFNAR1, are present in all tissues and even on the surface of most IFN-resistant cells. Isoform 1, isoform 2 and isoform 3 are expressed in the IFN-alpha sensitive myeloma cell line U266B1. Isoform 2 and isoform 3 are expressed in the IFN-alpha resistant myeloma cell line U266R. Isoform 1 is not expressed in IFN-alpha resistant myeloma cell line U266R. It interacts with STAT1 and STAT2, the interaction requires its phosphory...
TMPY-04451 AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST)

AMPK, AMPK(α1, β1, γ1)

Human Baculovirus Insect Cells
AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 160 kDa and the accession number is P54619-1&Q9Y478-1&Q13131-1.
TMPY-03878 Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His)

Integrin alpha V β6,ITGAV & ITGB6,integrin, al<...

Human HEK293 Cells
Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 190.4 kDa and the accession number is P06756-1&P18564-1.
TMPY-02501 CD3D & CD3E Heterodimer Protein, Human, Recombinant

CD3d molecule, δ (CD3-TCR complex),CD3-δ,CD3d molecule, delt...

Human HEK293 Cells
CD3D & CD3E Heterodimer Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 77.5 kDa and the accession number is P04234-1&P07766-1.
TMPY-02030 CD82 Protein, Human, Recombinant (His)

CD82 molecule,SAR2,R2,KAI-1,4F9,KAI1,C33,T...

Human HEK293 Cells
CD82, also known as KAI-1, structurally belongs to tetraspanin family while categorised as metastasis suppressor gene on functional grounds. KAI1/CD82 is localized on cell membrane and form interactions with other tetraspanins, integrins and chemokines which are respectively responsible for cell migration, adhesion and signalling. Downregulation of CD82 expression is associated with the advanced stages of many human cancers and correlates with the acquisition of metastatic potential. Recent stud...
TMPY-01894 SIGIRR Protein, Human, Recombinant (His)

TIR8,single immunoglobulin and toll-interleukin 1 r...

Human HEK293 Cells
SIGIRR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14 kDa and the accession number is Q6IA17-1.
TMPY-01247 FLT3 Protein, Human, Recombinant (T227M, His)

FLK2,FLK-2,CD135,STK1,fms-related tyrosine...

Human HEK293 Cells
FLT3 Protein, Human, Recombinant (T227M, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.7 kDa and the accession number is P36888-1.
TMPY-02779 Thyroid peroxidase Protein, Human, Recombinant (S257A & P725T, His)

thyroid peroxidase,MSA,TPX,TDH2A

Human Baculovirus Insect Cells
Thyroid peroxidase is a membrane-bound glycoprotein which belongs to the peroxidase family, XPO subfamily. It contains 1 EGF-like domain and 1 Sushi (CCP/SCR) domain. Thyroid Peroxidase represents one of the main autoantigenic targets in autoimmune thyroid disease of humans. It used to be taken as the formerly so-called `microsomal antigen` several years ago. As an integral membrane glycoprotein it is restricted to the apical plasma membrane of the follicular epithelial cells and comprises two i...
TMPY-04970 TIGIT Protein, Human, Recombinant (hFc)

WUCAM,VSTM3,VSIG9,T cell immunoreceptor with Ig and ITIM dom...

Human HEK293 Cells
TIGIT Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 39.2 kDa and the accession number is Q495A1-1.
TMPY-01147 R-Spondin 1/RSPO1 Protein, Human, Recombinant (His)

RSPO,CRISTIN3,R-spondin 1

Human HEK293 Cells
R-Spondin 1/RSPO1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.2 kDa and the accession number is Q2MKA7-1.
TMPY-04346 PD-L2 Protein, Human, Recombinant (His)

PD-L2,B7-DC,CD273,Btdc,PDCD1L2,B7DC,PDL2,programmed...

Human HEK293 Cells
PD-L2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the accession number is Q9BQ51-1.
TMPY-00947 VCAM-1 Protein, Human, Recombinant (hFc)

INCAM-100,CD106,VCAM-1,vascular c...

Human HEK293 Cells
VCAM-1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 100.8 kDa and the accession number is P19320-1.
TMPY-01949 CD19 Protein, Human, Recombinant (His)

CD19 molecule,B4,CVID3

Human HEK293 Cells
CD19 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.6 kDa and the accession number is P15391-1.
TMPY-04165 FGFR3 Protein, Human, Recombinant (His)

JTK4,CEK2,fibroblast growth factor receptor 3,HSFGFR3EX,CD33...

Human HEK293 Cells
FGFR3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.6 kDa and the accession number is P22607-1.
TMPY-00820 IgG1 Fc Protein, Human, Recombinant (C103S)

Ighg1,IgG1 Fc

Human HEK293 Cells
IgG1 Fc Protein, Human, Recombinant (C103S) is expressed in HEK293 mammalian cells. The predicted molecular weight is 26 kDa and the accession number is P01857-1.
TMPY-01146 Insulin Receptor Protein, Human, Recombinant (long isoform, His)

HHF5,CD220,insulin receptor

Human HEK293 Cells
Insulin Receptor Protein, Human, Recombinant (long isoform, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 107 kDa and the accession number is P06213-1.
TMPY-04348 CTLA-4 Protein, Human, Recombinant (His)

ALPS5,CD152,GRD4,cytotoxic T-lymphocyte-as...

Human HEK293 Cells
CTLA-4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15 kDa and the accession number is P16410-1.
TMPY-02813 ErbB4 Protein, Human, Rhesus, Recombinant (His)

erb-b2 receptor tyrosine kinase 4

Human,Rhesus HEK293 Cells
ErbB4 Protein, Human, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 71.1 kDa and the accession number is Q15303-1.
TMPY-05220 TSLP Protein, Human, Recombinant (R127A & R130S, His)

thymic stromal lymphopoietin

Human HEK293 Cells
TSLP Protein, Human, Recombinant (R127A & R130S, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16.2 kDa and the accession number is Q969D9-1.
TMPY-01827 CD30/TNFRSF8 Protein, Human, Recombinant (His)

D1S166E,tumor necrosis factor receptor sup...

Human HEK293 Cells
CD30/TNFRSF8 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is P28908-1.
TMPY-00853 IL-1RA Protein, Human, Recombinant

DIRA,IL1RA,interleukin 1 receptor antagoni...

Human E. coli
IL-1RA Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.3 kDa and the accession number is P18510-1.
TMPY-01850 CEACAM3 Protein, Human, Recombinant (His)

W282,W264,CEA,CD66D,CGM1,MGC11987...

Human HEK293 Cells
CeACAM3 (CD66d), a member of carcinoembryonic antigen family, is a granulocyte-specific receptor involved in the opsonin-independent recognition of several bacterial pathogens. There are four members in this family: CD66a, CD66b, CD66c, and CD66d. Members of CEACAM family are widely expressed especially on human neutrophils, and, depending on the tissue, capable of regulating diverse functions including tumor promotion, tumor suppression, angiogenesis, and neutrophil activation. Abnormal overexp...
TMPY-02245 SNAP-25 Protein, Human, Recombinant (His)

synaptosomal-associated protein, 25kDa,SEC9,SNAP,RI...

Human E. coli
Synaptosomal-associated protein 25, also known as Super protein, Synaptosomal-associated 25 kDa protein, SNAP25 and SNAP, is a cytoplasm and cell membrane protein that belongs to the SNAP-25 family. SNAP25 / SUP contains 2 t-SNARE coiled-coil homology domains. SNAP25 / SUP is a membrane bound protein anchored to the cytosolic face of membranes via palmitoyl side chains in the middle of the molecule. SNAP25 / SUP protein is a component of the SNARE complex, which is proposed to account for the sp...
TMPY-00203 LOXL2 Protein, Mouse, Recombinant (His)

1110004B06Rik,4930526G1<...

Mouse HEK293 Cells
Lysyl oxidase homolog 2, also known as Lysyl oxidase-like protein 2, Lysyl oxidase-related protein 2, Lysyl oxidase-related protein WS9-14 and LOXL2, is a secreted protein that belongs to the lysyl oxidase family. LOXL2 contains four SRCR domains. The lysyl oxidase family is made up of five members: lysyl oxidase (LOX) and lysyl oxidase-like 1-4 ( LOXL1, LOXL2, LOXL3, LOXL4 ). All members share conserved C-terminal catalytic domains that provide for lysyl oxidase or lysyl oxidase-like enzyme act...
TMPY-01281 ACVR2B Protein, Mouse, Recombinant (His)

ActRIIB,activin A receptor, type IIB,4930516B21...

Mouse HEK293 Cells
ACVR2B Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.8 kDa and the accession number is P27040-1.
TMPY-01851 CD73 Protein, Human, Recombinant (His)

eN,NT5,E5NT,NT,5'-nucleotidase, ecto (CD73),NTE,CAL...

Human HEK293 Cells
CD73 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.2 kDa and the accession number is P21589-1.
TMPY-02525 RGMA Protein, Human, Recombinant (His)

repulsive guidance molecule family member a,RGM

Human HEK293 Cells
RGMa, also known as RGM domain family, member A, belongs to the RGM (repulsive guidance molecule) family whose members are membrane-associated glycoprotein. RGMa is a glycosylphosphatidylinositol-anchored glycoprotein that functions as an axon guidance protein in the developing and adult central nervous system. It helps guide Retinal Ganglion Cell (RGC) axons to the tectum in the midbrain. RGMa has been implicated to play an important role in the developing brain and in the scar tissue that form...
TMPY-03967 BTN3A3 Protein, Human, Recombinant (His)

BTF3,BTN3.3,butyrophilin subfamily 3 member A3,BTN3A3

Human HEK293 Cells
BTN3A3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25 kDa and the accession number is O00478-1.
TMPY-05208 PD-L1 Protein, Human, Recombinant

CD274 molecule,PDCD1L1,PD-L1,PDL<...

Human HEK293 Cells
PD-L1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 25.2 kDa and the accession number is Q9NZQ7-1.
TMPY-00978 Progranulin Protein, Human, Recombinant (His)

PGRN,PCDGF,CLN11,Granulin,GP88,GEP,Granuli...

Human HEK293 Cells
Progranulin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 63.2 kDa and the accession number is P28799-1.
TMPY-03407 NQO1 Protein, Human, Recombinant (His)

NAD(P)H dehydrogenase, quinone 1,NMORI,DIA4,QR1...

Human E. coli
NQO1 gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. NQO1 forms homodimers and reduces quinones to hydroquinones. NQO1's enzymatic activity prevents the one-electron reduction of quinones that results in the production of radical species. Mutations in the NQO1 gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered ex...
TMPY-01258 IL-13RA1 Protein, Human, Recombinant (His)

NR4,interleukin 13 receptor, alpha 1

Human HEK293 Cells
IL-13RA1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.3 kDa and the accession number is P78552-1.
TMPY-03531 PSGL-1/CD162 Protein, Human, Recombinant (His)

selectin P ligand,PSGL-1,PSGL1,CD1

Human HEK293 Cells
PSGL-1/CD162 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 30.5 kDa and the accession number is Q14242-1.
TMPY-01883 EPOR Protein, Human, Recombinant (His)

erythropoietin receptor,EPO-R

Human HEK293 Cells
EPOR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.3 kDa and the accession number is P19235-1.
TMPY-01862 IL-4 Protein, Human, Recombinant

Interleukin-4,IL-4,BCGF1,白细胞介素,interleukin 4,BSF

Human E. coli
IL-4 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 15.1 kDa and the accession number is P05112-1.
TMPY-06418 R-Spondin 2/RSPO2 Protein, Human, Recombinant (hFc)

R-spondin 2,CRISTIN2

Human HEK293 Cells
R-Spondin 2/RSPO2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48.01 kDa and the accession number is Q6UXX9-1.
TMPY-04333 LRRC15 Protein, Human, Recombinant (hFc)

leucine rich repeat containing 15,LIB

Human HEK293 Cells
LRRC15 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 84.5 kDa and the accession number is Q8TF66-1.
TMPY-02033 CD44 Protein, Human, Recombinant (His)

CD44 molecule (Indian blood group),IN,MC56,HUTCH-I,MIC4,CDW4...

Human HEK293 Cells
CD44 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 23.4 kDa and the accession number is P16070-1.
TMPY-04939 LAG-3 Protein, Human, Recombinant

LAG-3,lymphocyte-activation gene 3,CD223

Human HEK293 Cells
LAG-3 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 45.3 kDa and the accession number is P18627-1.
TMPY-04104 LIF Protein, Human, Recombinant

CDF,DIA,白血病抑制因子,MLPLI,Leukemia Inhibitory Factor,HILDA

Human HEK293 Cells
LIF Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 19.7 kDa and the accession number is P15018-1.
TMPY-00861 IL-33 Protein, Human, Recombinant

IL1F11,C9orf26,NFEHEV,NF-HEV,DVS2...

Human E. coli
IL-33 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 18 kDa and the accession number is O95760-1.
TMPY-06873 FLT3 Ligand Protein, Human, Recombinant

FLT3LG,fms related tyrosine kinase 3 ligand,FLT3L,FL

Human E. coli
FLT3 Ligand Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.75 kDa and the accession number is P49771-1.
TMPY-01185 DR5/TRAIL R2 Protein, Human, Recombinant (His)

KILLER,TRICK2A,TRICK2,DR5,TRICKB,tumor necrosis factor recep...

Human HEK293 Cells
DR5/TRAIL R2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.7 kDa and the accession number is O14763-1.
TMPY-01938 CD98 Protein, Human, Recombinant (His)

4T2HC,4F2,CD98HC,NACAE,MDU1,4F2HC,CD98,solute carri...

Human HEK293 Cells
CD98 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 49.2 kDa and the accession number is P08195-1.
TMPY-01137 HER2/ERBB2 Protein, Human, Recombinant (aa 1-652, His)

erb-b2 receptor tyrosine kinase 2,NEU,ENVW,HERV-7q,HERV7Q,HE...

Human HEK293 Cells
HER2/ERBB2 Protein, Human, Recombinant (aa 1-652, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 71 kDa and the accession number is P04626-1.
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重组蛋白

Ephrin A5/EFNA5 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-01749
Species: Mouse
Expression System: HEK293 Cells
Ephrin A5/EFNA5 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01748
Species: Mouse
Expression System: HEK293 Cells
HSP90 alpha Protein, Mouse, Recombinant (His)
Cat.No: TMPY-06846
Species: Mouse
Expression System: Baculovirus Insect Cells
OR5AL1 Protein, Human, Recombinant (His)
Cat.No: TMPH-01810
Species: Human
Expression System: E. coli
Peroxiredoxin 2 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-05169
Species: Mouse
Expression System: Baculovirus Insect Cells
IFNAR1 Protein, Rhesus macaque, Recombinant (His)
Cat.No: TMPJ-00331
Species: Rhesus
Expression System: HEK293 Cells
AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-04451
Species: Human
Expression System: Baculovirus Insect Cells
Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His)
Cat.No: TMPY-03878
Species: Human
Expression System: HEK293 Cells
CD3D & CD3E Heterodimer Protein, Human, Recombinant
Cat.No: TMPY-02501
Species: Human
Expression System: HEK293 Cells
CD82 Protein, Human, Recombinant (His)
Cat.No: TMPY-02030
Species: Human
Expression System: HEK293 Cells
SIGIRR Protein, Human, Recombinant (His)
Cat.No: TMPY-01894
Species: Human
Expression System: HEK293 Cells
FLT3 Protein, Human, Recombinant (T227M, His)
Cat.No: TMPY-01247
Species: Human
Expression System: HEK293 Cells
Thyroid peroxidase Protein, Human, Recombinant (S257A & P725T, His)
Cat.No: TMPY-02779
Species: Human
Expression System: Baculovirus Insect Cells
TIGIT Protein, Human, Recombinant (hFc)
Cat.No: TMPY-04970
Species: Human
Expression System: HEK293 Cells
R-Spondin 1/RSPO1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01147
Species: Human
Expression System: HEK293 Cells
PD-L2 Protein, Human, Recombinant (His)
Cat.No: TMPY-04346
Species: Human
Expression System: HEK293 Cells
VCAM-1 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00947
Species: Human
Expression System: HEK293 Cells
CD19 Protein, Human, Recombinant (His)
Cat.No: TMPY-01949
Species: Human
Expression System: HEK293 Cells
FGFR3 Protein, Human, Recombinant (His)
Cat.No: TMPY-04165
Species: Human
Expression System: HEK293 Cells
IgG1 Fc Protein, Human, Recombinant (C103S)
Cat.No: TMPY-00820
Species: Human
Expression System: HEK293 Cells
Insulin Receptor Protein, Human, Recombinant (long isoform, His)
Cat.No: TMPY-01146
Species: Human
Expression System: HEK293 Cells
CTLA-4 Protein, Human, Recombinant (His)
Cat.No: TMPY-04348
Species: Human
Expression System: HEK293 Cells
ErbB4 Protein, Human, Rhesus, Recombinant (His)
Cat.No: TMPY-02813
Species: Human,Rhesus
Expression System: HEK293 Cells
TSLP Protein, Human, Recombinant (R127A & R130S, His)
Cat.No: TMPY-05220
Species: Human
Expression System: HEK293 Cells
CD30/TNFRSF8 Protein, Human, Recombinant (His)
Cat.No: TMPY-01827
Species: Human
Expression System: HEK293 Cells
IL-1RA Protein, Human, Recombinant
Cat.No: TMPY-00853
Species: Human
Expression System: E. coli
CEACAM3 Protein, Human, Recombinant (His)
Cat.No: TMPY-01850
Species: Human
Expression System: HEK293 Cells
SNAP-25 Protein, Human, Recombinant (His)
Cat.No: TMPY-02245
Species: Human
Expression System: E. coli
LOXL2 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-00203
Species: Mouse
Expression System: HEK293 Cells
ACVR2B Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01281
Species: Mouse
Expression System: HEK293 Cells
CD73 Protein, Human, Recombinant (His)
Cat.No: TMPY-01851
Species: Human
Expression System: HEK293 Cells
RGMA Protein, Human, Recombinant (His)
Cat.No: TMPY-02525
Species: Human
Expression System: HEK293 Cells
BTN3A3 Protein, Human, Recombinant (His)
Cat.No: TMPY-03967
Species: Human
Expression System: HEK293 Cells
PD-L1 Protein, Human, Recombinant
Cat.No: TMPY-05208
Species: Human
Expression System: HEK293 Cells
Progranulin Protein, Human, Recombinant (His)
Cat.No: TMPY-00978
Species: Human
Expression System: HEK293 Cells
NQO1 Protein, Human, Recombinant (His)
Cat.No: TMPY-03407
Species: Human
Expression System: E. coli
IL-13RA1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01258
Species: Human
Expression System: HEK293 Cells
PSGL-1/CD162 Protein, Human, Recombinant (His)
Cat.No: TMPY-03531
Species: Human
Expression System: HEK293 Cells
EPOR Protein, Human, Recombinant (His)
Cat.No: TMPY-01883
Species: Human
Expression System: HEK293 Cells
IL-4 Protein, Human, Recombinant
Cat.No: TMPY-01862
Species: Human
Expression System: E. coli
R-Spondin 2/RSPO2 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-06418
Species: Human
Expression System: HEK293 Cells
LRRC15 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-04333
Species: Human
Expression System: HEK293 Cells
CD44 Protein, Human, Recombinant (His)
Cat.No: TMPY-02033
Species: Human
Expression System: HEK293 Cells
LAG-3 Protein, Human, Recombinant
Cat.No: TMPY-04939
Species: Human
Expression System: HEK293 Cells
LIF Protein, Human, Recombinant
Cat.No: TMPY-04104
Species: Human
Expression System: HEK293 Cells
IL-33 Protein, Human, Recombinant
Cat.No: TMPY-00861
Species: Human
Expression System: E. coli
FLT3 Ligand Protein, Human, Recombinant
Cat.No: TMPY-06873
Species: Human
Expression System: E. coli
DR5/TRAIL R2 Protein, Human, Recombinant (His)
Cat.No: TMPY-01185
Species: Human
Expression System: HEK293 Cells
CD98 Protein, Human, Recombinant (His)
Cat.No: TMPY-01938
Species: Human
Expression System: HEK293 Cells
HER2/ERBB2 Protein, Human, Recombinant (aa 1-652, His)
Cat.No: TMPY-01137
Species: Human
Expression System: HEK293 Cells
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Cat. No. Product Name Target Signaling Pathways
T35915 Erlotinib-13C6

Erlotinib-13C6

Erlotinib-13C6 (CP-358774-13C6) is a 13C-labeled Erlotinib. Erlotinib is a directly acting EGFR tyrosine kinase inhibitor, with an IC50 of 2 nM for human EGFR[1]. Erlotinib reduces EGFR autophosphorylation in intact tumor cells with an IC50 of 20 nM. Erlotinib is used for the treatment of non-small cell lung cancer[1].Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process[2]...
T37044 1,2-Dioleoyl-rac-glycerol-13C3

1,2-Dioleoyl-rac-glycerol-13C3

1,2-Dioleoyl-rac-glycerol-13C3 is intended for use as an internal standard for the quantification of 1,2-dioleoyl-rac-glycerol by GC- or LC-MS. 1,2-dioleoyl-rac-glycerol is a diacylglycerol that contains oleic acid at the sn-1 and sn-2 positions. It effectively binds the C1 domain to activate conventional protein kinase C forms and serves as a substrate for diacylglycerol kinases and multisubstrate lipid kinase.1,2,3 |1. Yamaguchi, Y., Shirai, Y., Matsubara, T., et al. Phosphorylation and up-reg...
T35698 Octanoic Acid-13C

Octanoic acid-13C is intended for use as an internal standard for the quantification of octanoic acid by GC- or LC-MS. Octanoic acid is a medium-chain saturated fatty acid. It has been found in Teleme cheeses made from goat, ovine, or bovine milk.1 Octanoic acid is active against the bacteria S. mutans, S. gordonii, F. nucleatum, and P. gingivalis (IC80s = <125, <125, 1,403, and 2,294 μM, respectively).2 Levels of octanoic acid are increased in the plasma of patients with medium-chain acyl-CoA d...
T37847 Zonisamide-13C2,15N

Zonisamide-13C2,15N

Zonisamide-13C2,15N is intended for use as an internal standard for the quantification of zonisamide by GC- or LC-MS. Zonisamide is an antiepileptic agent.1 It selectively inhibits the repeated firing of sodium channels (IC50 = 2 μg/ml) in mouse embryo spinal cord neurons and inhibits spontaneous channel firing when used at concentrations greater than 10 μg/ml.2 In rat cerebral cortex neurons, zonisamide (1-1,000 μM) inhibits T-type calcium channels with a maximum reduction of 60% of the calcium...
T35789 Palmitic acid-1-13C

Palmitic acid-13C is intended for use as an internal standard for the quantification of palmitic acid by GC- or LC-MS. Palmitic acid is a 16-carbon saturated fatty acid. It comprises approximately 25% of human total plasma lipids.1 It increases protein levels of COX-2 in RAW 264.7 cells when used at a concentration of 75 μM.2 Palmitic acid is involved in the acylation of proteins to anchor membrane-bound proteins to the lipid bilayer.2,3,4,5,6 |1. Santos, M.J., López-Jurado, M., Llopis, J., et a...
T35791 Palmitic acid-13C

Palmitic acid-13C is intended for use as an internal standard for the quantification of palmitic acid by GC- or LC-MS. Palmitic acid-13C contains 13C at the C2 position and has been used in the study of free fatty acid incorporation into phospholipid fatty acids in soil microbes.1 Palmitic acid is a 16-carbon saturated fatty acid. It comprises approximately 25% of human total plasma lipids.2 It increases protein levels of COX-2 in RAW 264.7 cells when used at a concentration of 75 μM.3 Palmitic ...
T36055 Nitisinone-13C6

Nitisinone-13C6

Nitisinone-13C6is intended for use as an internal standard for the quantification of nitisinone by GC- or LC-MS. Nitisinone is an inhibitor of 4-hydroxyphenylpyruvate dioxygenase (HPPD), which converts 4-hydroxyphenylpyruvate (HPPA) to homogentisate in the tyrosine catabolic pathway.1Nitisinone increases urinary levels of HPPA and 4-hydroxyphenyllactate (HPLA) in rats when administered at a dose of 10 mg/kg. Nitisinone (3 mg/kg) prevents the neonatal lethality of fumarylacetoacetate hydrolase (F...
T38356 1,2-Dipalmitoyl-13C-sn-glycero-3-PC

1,2-Dipalmitoyl-13C-sn-glycero-3-PC is intended for use as an internal standard for the quantification of 1,2-dipalmitoyl-sn-glycero-3-PC by GC- or LC-MS. 1,2-Dipalmitoyl-sn-glycero-3-PC (DPPC) is a zwitterionic glycerophospholipid commonly used in the formation of lipid monolayers, bilayers, and liposomes for use in a variety of applications.1,2,3,4 It has been used in the formation of proteoliposomes for implantation of γ-glutamyl transpeptidase into human erythrocyte membranes.3 Incorporation...
T35775 HT-2 Toxin-13C22

HT-2 Toxin-13C22

HT-2 toxin-13C22is intended for use as an internal standard for the quantification of HT-2 toxin by GC- or LC-MS. HT-2 toxin is a type A trichothecene mycotoxin and an active, deacetylated metabolite of the trichothecene mycotoxin T-2 toxin .1,2Like T-2 toxin, HT-2 toxin inhibits protein synthesis and cell proliferation in plants.2HT-2 toxin also reduces viability of HepG2, A549, HEp-2, Caco-2, A-204, U937, Jurkat, and RPMI-8226 cancer cells with IC50values ranging from 3.1 to 23 ng/ml and human...

同位素标记化合物

Erlotinib-13C6
Cat.No: T35915
Synonym: Erlotinib-13C6
Target:
1,2-Dioleoyl-rac-glycerol-13C3
Cat.No: T37044
Synonym: 1,2-Dioleoyl-rac-glycerol-13C3
Target:
Octanoic Acid-13C
Cat.No: T35698
Synonym:
Target:
Zonisamide-13C2,15N
Cat.No: T37847
Synonym: Zonisamide-13C2,15N
Target:
Palmitic acid-1-13C
Cat.No: T35789
Synonym:
Target:
Palmitic acid-13C
Cat.No: T35791
Synonym:
Target:
Nitisinone-13C6
Cat.No: T36055
Synonym: Nitisinone-13C6
Target:
1,2-Dipalmitoyl-13C-sn-glycero-3-PC
Cat.No: T38356
Synonym:
Target:
HT-2 Toxin-13C22
Cat.No: T35775
Synonym: HT-2 Toxin-13C22
Target:
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