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Search Results for " aids "

Targets Recommended: Epigenetic Reader Domain CDK

59

抑制剂 & 化合物

11

天然产物

2

化合物库

5

重组蛋白

6

同位素标记化合物

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Cat. No.	Product Name
L1700	抗病毒库		1040 compounds
	1040 种具有抗病毒活性的化合物的特有集合，是筛选新型抗病毒药的有效工具；可用于高通量筛选和高内涵筛选；
L1100	蛋白酶抑制剂库		343 compounds
	343 种已知的小分子蛋白酶抑制剂的特有集合，可用于高通量筛选和高内涵筛选；

化合物库

Cat.No: L1700

Compounds: 1040

蛋白酶抑制剂库

Cat.No: L1100

Compounds: 343

Cat. No.	Product Name	Target	Signaling Pathways
T6255	Bromosporine	Epigenetic Reader Domain; CDK	Cell Cycle/Checkpoint; Chromatin/Epigenetic
	Bromosporine 是广谱 BRD2/4/9 和 CECR2 溴结构域抑制剂，IC50为0.41、0.29、0.122和0.017 μM。
T20062	Thiamine disulfide 二硫化硫胺,TDS,Daiomin,Algoneurina	HIV Protease; Endogenous Metabolite	Metabolism; Microbiology/Virology; Proteases/Proteasome
	Thiamine disulfide (Algoneurina) 是一种存在于食物中的维生素，可作为膳食补充剂和药物生产。它还充当许多中枢代谢酶的辅助因子。
T6098	Cabotegravir GSK744,GSK-1265744,卡博特韦,S/GSK1265744	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Cabotegravir (S/GSK1265744) 是一种HIV 整合酶抑制剂，可研究艾滋病。它抑制OAT1 和OAT3，IC50值为 0.81 和0.41 μM。
T7212	Delavirdine mesylate U 90152 (mesylate),BHAP-U 90152 (mesylate),Delavirdine (mesylate)	HIV Protease; Reverse Transcriptase	Microbiology/Virology; Proteases/Proteasome
	Delavirdine mesylate (BHAP-U 90152(mesylate)) 是一种口服活性非核苷逆转录酶抑制剂。它抑制 HIV-1 病毒复制，可以用于艾滋病的相关研究。它选择性地抑制 HIV-1 逆转录酶，其选择性超过 DNA 聚合酶 α 和 DNA 聚合酶 δ 。
T1267	Abacavir Epzicom,Ziagen,阿巴卡韦	Apoptosis; HIV Protease; Reverse Transcriptase	Apoptosis; Microbiology/Virology; Proteases/Proteasome
	Abacavir (Ziagen) 是一种核苷类似物逆转录酶抑制剂。
T70852	Atevirdine U 85961	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Atevirdine 是一种 HIV-1 逆转录酶抑制剂，具有抗病毒活性，可用于研究艾滋病痴呆复合体(ADC)。
T3335	Darunavir Ethanolate 地瑞那韦乙醇盐,UIC 94017,Darunavir Ethanolate,TMC114,达芦那韦乙醇	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Darunavir Ethanolate (UIC 94017) 是一种HIV 蛋白酶抑制剂，可以用于 HIV/AIDS 的相关研究。对野生型 HIV-1 蛋白酶的Ki 值为1 nM。
T1595	Nevirapine NSC 641530,奈韦拉平,BI-RG 587,奈伟拉平,NVP	HIV Protease; Reverse Transcriptase	Microbiology/Virology; Proteases/Proteasome
	Nevirapine (NVP) 是一种 HIV-1逆转录酶非核苷抑制剂，Ki 值为 270 μM，可用于研究 HIV/AIDS。
T3632	Doravirine 多拉维林,多拉韦林,MK-1439	HIV Protease; Reverse Transcriptase	Microbiology/Virology; Proteases/Proteasome
	Doravirine (MK-1439) 是一种高度特异性的HIV-1非核苷逆转录酶抑制剂，对野生型以及K103N 和Y181C 逆转录酶突变体的IC50值分别为 4.5 nM，5.5 nM 和 6.1 nM。
T7903	Saquinavir Ro 31-8959,沙奎那韦	SARS-CoV; HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Saquinavir (Ro 31-8959) 是一种 HIV 蛋白酶抑制剂，可研究逆转录病毒。它也是 SARS-CoV 3CLpro 抑制剂，IC50为 1.36 μM。
T4697	ABBV-744 ABBV744	Epigenetic Reader Domain; HIV Protease	Chromatin/Epigenetic; Microbiology/Virology; Proteases/Proteasome
	ABBV-744 是一种 BDII 选择性 BET 溴结构域抑制剂，可抑制 BRD2/3/4。它可研究炎症性疾病、癌症和艾滋病。
T24362	L 756423 L756423,MK-944a,MK944a,L-756,423,L-756423,MK 944a	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	L 756423 (L756423) 是一种新型有效且具有选择性和竞争性的HIV蛋白酶抑制剂，对 HIV-1 PR 的 Ki 值为0.049 nM。L 756423 能阻止HIV(IIIb)感染的 MT25 淋巴细胞在0.50-0.1nM处的扩散，可用于研究获得性免疫缺陷综合征(AIDS)。
T0688	Ganciclovir BW 759,更昔洛韦,RS-21592,2'-Nor-2'-deoxyguanosine	Nucleoside Antimetabolite/Analog; Others; Antibiotic; Antifection; HSV	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology; Others
	Ganciclovir (2'-Nor-2'-deoxyguanosine) 是核苷类似物和口服抗病毒药物，对CMV 具有抗病毒活性。它用于治疗与艾滋病相关的巨细胞病毒感染的并发症。
T0100	Atazanavir sulfate 阿扎那韦硫酸盐,BMS-232632,BMS-232632 sulfate,硫酸阿扎那韦	P450; SARS-CoV; HIV Protease; P-gp	Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Neuroscience; Proteases/Proteasome
	Atazanavir sulfate (BMS-232632 sulfate) 是一种氮杂肽和 HIV 蛋白酶抑制剂，与其他抗 HIV 药物联合用于治疗 HIV 感染和艾滋病。它也是SARS-CoV 3CLpro 抑制剂，IC50为 3.49 μM。
T6367	Abacavir sulfate Abacavir Hemisulfate,硫酸阿巴卡韦,1592U89,ABC sulfate,Ziagen	Apoptosis; HIV Protease; Reverse Transcriptase	Apoptosis; Microbiology/Virology; Proteases/Proteasome
	Abacavir sulfate (Ziagen) 是一种核苷类似物逆转录酶抑制剂，可用于 HIV 和 AIDS。
T2324	Darunavir 地瑞那韦,达芦那韦,TMC114	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Darunavir (TMC114) 是一种 HIV 蛋白酶抑制剂，用于治疗艾滋病和 HIV 感染。由于单独使用时会出现抗病毒药物耐药性，因此与其他抗 HIV 药物联合使用。
T8736	Cidofovir dihydrate HPMPC,(S)-HPMPC,GS 0504,西多福韦二水合物	Others	Others
	Cidofovir dihydrate (HPMPC) 是注射型巨细胞病毒 DNA 聚合酶抑制剂，通过选择性抑制病毒 DNA 聚合酶来抑制 CMV 复制，从而阻止病毒复制和转录。
T8826	3-AMINO-1,2,4-TRIAZINE	Others	Others
	3-AMINO-1,2,4-TRIAZINE 是一种芳香族生物活性化合物，已用于合成各种药物，包括抗真菌药物氟康唑、抗炎药物布洛芬和抗癌药物紫杉醇；也被用于设计新药，如抗艾滋病药物齐多夫定和抗疟疾药物青蒿素；以及用于合成各种其他化合物，如抗糖尿病药物二甲双胍和抗高血压药物赖诺普利。
T1525	Ritonavir RTV,利托那韦,Abbott 84538,A 84538,ABT 538	Apoptosis; SARS-CoV; HIV Protease	Apoptosis; Microbiology/Virology; Proteases/Proteasome
	Ritonavir (ABT 538) 是一种 HIV 蛋白酶抑制剂，可研究 HIV 感染和 AIDS 。它也是 SARS-CoV 3CLpro 的抑制剂，IC50为 1.61 μM。
T0377	Clofazimine NSC-141046,氯法齐明,氯苯吩嗪	DNA; Antibacterial; Antibiotic	DNA Damage/DNA Repair; Microbiology/Virology
	Clofazimine (NSC-141046) 是一种具有显著的抗炎效果的亚氨基酚嗪类染料，与其它抗分支杆菌药物联用来治疗AIDS 和克罗恩病。
T28306	PD 099560 PD099560,PD-099560	Others	Others
	PD 099560 is a non-peptide inhibitor of HIV-1 protease, a significant target enzyme in AIDS research.
T71517	Nevirapine quinone methide	Others	Others
	Nevirapine quinone methide is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used to treat HIV-1 infection and AIDS.
T70717	KNI 174	Others	Others
	KNI 174 is a new type of anti‐AIDS drug used as an HIV‐1 protease inhibitor
T25535	Indinavir, threo- Threo-indinavir,Indinavir sulfate specified impurity C	Others	Others
	Indinavir, threo- is a protease inhibitor utilized as a component of highly active antiretroviral treatment to HIV/AIDS.
T68376	Indinavir lactone	Others	Others
	Indinavir lactone is a protease inhibitor used as a component of highly active antiretroviral therapy to treat HIV/AIDS.
T5863L	Indinavir 茚地那韦,MK-639,L 735 524,Crixivan	Others	Others
	Indinavir (IDV) is an inhibitor of protease that is used as part of highly active antiretroviral therapy for the treatment of HIV/AIDS.
T27171	Diethylhomospermine DEHOP,BE-4-4-4,DEHSPM,DE-444	Others	Others
	Diethylhomospermine is a drug potentially for the treatment of AIDS-related chronic diarrhea.Diethylhomospermine also shows promising anticancer activity.
T70147	Fipravirimat	Others	Others
	Fipravirimat 是一种有效的 HIV-1抑制剂。Fipravirimat 具有用于HIV 和 AIDS 研究的潜力。
TP2401	Peptide T amide D-Ala(1)-peptide T amide
	Peptide T amide is an octapeptide segment of HIV envelope gp120 and is used in AIDS therapy.
T69796	Nevirapine hemihydrate	Others	Others
	Nevirapine hemihydrate is a non-nucleoside reverse transcriptase inhibitor (NNRTI) studied for potential treatment of HIV-1 infection and AIDS.
T74106	Hydroxy ritonavir	Others	Others
	Hydroxy ritonavir 是 Ritonavir 的代谢物。Ritonavir 是用于研究HIV 感染和 AIDS 的HIV 蛋白酶的抑制剂。
T63602	ddCTP trisodium	Others	Others
	ddCTP trisodium 是一种核苷类似物，靶向人类免疫缺陷病毒 (HIV) 的逆转录酶，可用于研究艾滋病 (AIDS)。ddCTP trisodium 是一类双脱氧核糖核苷酸 (ddNTPs)，也是一种 DNA 聚合酶链延长抑制剂，能够用于 DNA 测序的研究。
T62690	HIV-1 inhibitor-46	Others	Others
	HIV-1 inhibitor-46 (compound 13d) 是一种 HIV-1 非核苷类逆转录酶的有效抑制剂 (EC50: 1.425 μM)。HIV-1 inhibitor-46 能够用于研究艾滋病 (AIDS)。
T62070	HIV-1 inhibitor-31	Others	Others
	HIV-1 inhibitor-31 (compound 4) 是一种 HIV-1 的有效抑制剂。HIV-1 inhibitor-31 能够用于研究艾滋病。
T72568	HIV-1 inhibitor-53	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	HIV-1inhibitor-53 是一种抑制HIV-1蛋白酶（PR）与逆转录酶（RT）的双重抑制剂，其IC50值分别为1.93 nM与2.35 μM，用于获得性免疫缺陷综合征（AIDS）相关的研究。
T71518	Zidovudine diphosphate	Others	Others
	Zidovudine diphosphate is an antiretroviral medication used to prevent and treat HIV/AIDS. It is of the nucleoside analog reverse-transcriptase inhibitor (NRTI) class. Zidovudine inhibits the enzyme (reverse transcriptase) that HIV uses to synthesize DNA, thus preventing viral DNA from forming.
T71983	Zidovudine glucuronide	Others	Others
	Zidovudine glucuronide is an antiretroviral medication used to prevent and treat HIV/AIDS. It is of the nucleoside analog reverse-transcriptase inhibitor (NRTI) class. Zidovudine inhibits the enzyme (reverse transcriptase) that HIV uses to synthesize DNA, thus preventing viral DNA from forming.
T39068	Fomivirsen sodium	Others	Others
	Fomivirsen sodium is an antisense 21 mer phosphorothioate oligonucleotide. Fomivirsen is an antiviral agent that is used cytomegalovirus retinitis (CMV) research, incluiding in AIDs. Fomivirsen sodium binds to and degrades the mRNAs encoding CMV immediate-early 2 protein (required for viral replication), thus providing bioactive effects for CMV retinitis by inhibition of virus proliferation.
T71066	Cidofovir sodium	Others	Others
	Cidofovir sodium is the salt form of Cidofovir, a Cytomegalovirus Nucleoside Analog DNA Polymerase Inhibitor that is an injectable antiviral medication primarily used as a treatment for cytomegalovirus (CMV) retinitis in people with AIDS. The mechanism of action of cidofovir is as a DNA Polymerase Inhibitor. The chemical classification of cidofovir anhydrous is Nucleoside Analog.
T74939	HIV protease-IN-1	Others	Others
	HIVprotease-IN-1 (compound 1·succinate) 是一种有效的HIV 蛋白酶 (HIV protease) 非肽抑制剂，可用于艾滋病的研究。
T19228	Calcitriol Impurities D 24-Homo Calcitriol,24-Homo-1,25-dihydroxyvitamin D3	Antiviral	Immunology/Inflammation
	Calcitriol Impurities D (24-Homo Calcitriol) 是维生素的一种激素形式，可促进HL-60人早幼粒细胞白血病细胞分化为单核细胞。Calcitriol Impurities D 具有骨吸收活性，抑制人类免疫缺陷病毒在人体细胞中的复制。Calcitriol Impurities D 具有抗病毒活性们可以用于治疗艾滋病和病毒感染。
T63306	HIV-1 inhibitor-32	Others	Others
	HIV-1 inhibitor-32 是 HIV-1 的有效抑制剂，能够作用于野生型 HIV (IC50: 34 nM)，能够用于研究艾滋病。
T84453	1-Palmitoyl-2-Lauroyl-sn-glycero-3-PC 1-Palmitoyl-2-Lauroyl-sn-glycero-3-Phosphatidylcholine	Others	Others
	1-Palmitoyl-2-lauroyl-sn-glycero-3-PC (1,2-PLPC) is a phospholipid with palmitoyl (16:0) and lauryl (12:0) acyl chains at the sn-1 and sn-2 positions, respectively. This mixed-chain phosphatidylcholine aids in researching the role of chain-chain contact interactions in maintaining the structural stability of lipid membrane bilayers.
T83488	[Lys8] Vasopressin Desglycinamide
	"[Lys8] Vasopressin Desglycinamide，一种抗利尿激素类似物，主要应用于促进主动及被动回避行为的维持。该化合物有助于记忆巩固过程。"
T64303	ZLM-66	Others	Others
	ZLM-66 是一种多拉维林 (Doravirine) 类似物，也是一种 non-nucleoside reverse transcriptase (NNRTIs) 的有效抑制剂，能够作用于野生型 HIV-1 逆转录酶 (IC50: 41 nM)、野生型 HIV-1 (EC50: 13 nM)。ZLM-66 能够用于研究艾滋病 (AIDS)。
T62782	HIV-1 inhibitor-34	Others	Others
	HIV-1 inhibitor-34 (compound 5q) 是一种有效的、选择性的 HIV-1 抑制剂，作用于 HIV-1 (EC50: 6.4 nM)、MT-4 细胞 (CC50: 16 μM)。HIV-1 inhibitor-34 能够用于研究艾滋病。
T75232	2’-O-Acetyl-5’-O-benzoyl-3’-O-(2-methoxyethyl) uridine	Others	Others
	2’-O-Acetyl-5’-O-benzoyl-3’-O-(2-methoxyethyl) uridine 是一种具有抗癫痫潜能的尿嘧啶核苷类似物。其不仅用于研究抗惊厥和抗焦虑活性，也用于开发新型降压药物。
T75112	LSN3160440	Others	Others
	LSN3160440 是GLP-1R 的变构调节剂，可作为蛋白-蛋白相互作用（PPI）的稳定剂或分子胶，协助无活性GLP-1 (9-36) NH2粘附在GLP-1R 上。
T62353	HIV-1 inhibitor-33	Others	Others
	HIV-1 inhibitor-33 (compound 5n) 是一种有效的、选择性的 HIV-1 抑制剂，作用于 HIV-1 (EC50: 8.6 nM)、MT-4 细胞 (CC50: 18 μM)。HIV-1 inhibitor-33 能够用于研究艾滋病。
T80963	TPEQM-DMA
	TPEQM-DMA为近红外二区光敏剂，能在癌性线粒体中积累，抑制癌细胞生长。其显著I型光疗效果，有助于克服光动力疗法(PDT)治疗低氧肿瘤的限制。

化合物

Cat.No: T6255

Target: Epigenetic Reader Domain, CDK

Thiamine disulfide

Cat.No: T20062

Synonym: 二硫化硫胺,TDS,Daiomin,Algoneurina

Target: HIV Protease, Endogenous Metabolite

Cat.No: T6098

Synonym: GSK744,GSK-1265744,卡博特韦,S/GSK1265744

Target: HIV Protease

Delavirdine mesylate

Cat.No: T7212

Synonym: U 90152 (mesylate),BHAP-U 90152 (mesylate),Delavirdine (mesylate)

Target: HIV Protease, Reverse Transcriptase

Cat.No: T1267

Synonym: Epzicom,Ziagen,阿巴卡韦

Target: Apoptosis, HIV Protease, Reverse Transcriptase

Cat.No: T70852

Synonym: U 85961

Target: HIV Protease

Darunavir Ethanolate

Cat.No: T3335

Synonym: 地瑞那韦乙醇盐,UIC 94017,Darunavir Ethanolate,TMC114,达芦那韦乙醇

Target: HIV Protease

Cat.No: T1595

Synonym: NSC 641530,奈韦拉平,BI-RG 587,奈伟拉平,NVP

Target: HIV Protease, Reverse Transcriptase

Cat.No: T3632

Synonym: 多拉维林,多拉韦林,MK-1439

Target: HIV Protease, Reverse Transcriptase

Cat.No: T7903

Synonym: Ro 31-8959,沙奎那韦

Target: SARS-CoV, HIV Protease

Cat.No: T4697

Synonym: ABBV744

Target: Epigenetic Reader Domain, HIV Protease

Cat.No: T24362

Synonym: L756423,MK-944a,MK944a,L-756,423,L-756423,MK 944a

Target: HIV Protease

Cat.No: T0688

Synonym: BW 759,更昔洛韦,RS-21592,2'-Nor-2'-deoxyguanosine

Target: Nucleoside Antimetabolite/Analog, Others, Antibiotic, Antifection, HSV

Atazanavir sulfate

Cat.No: T0100

Synonym: 阿扎那韦硫酸盐,BMS-232632,BMS-232632 sulfate,硫酸阿扎那韦

Target: P450, SARS-CoV, HIV Protease, P-gp

Abacavir sulfate

Cat.No: T6367

Synonym: Abacavir Hemisulfate,硫酸阿巴卡韦,1592U89,ABC sulfate,Ziagen

Target: Apoptosis, HIV Protease, Reverse Transcriptase

Cat.No: T2324

Synonym: 地瑞那韦,达芦那韦,TMC114

Target: HIV Protease

Cidofovir dihydrate

Cat.No: T8736

Synonym: HPMPC,(S)-HPMPC,GS 0504,西多福韦二水合物

Target: Others

3-AMINO-1,2,4-TRIAZINE

Cat.No: T8826

Target: Others

Cat.No: T1525

Synonym: RTV,利托那韦,Abbott 84538,A 84538,ABT 538

Target: Apoptosis, SARS-CoV, HIV Protease

Cat.No: T0377

Synonym: NSC-141046,氯法齐明,氯苯吩嗪

Target: DNA, Antibacterial, Antibiotic

Cat.No: T28306

Synonym: PD099560,PD-099560

Target: Others

Nevirapine quinone methide

Cat.No: T71517

Target: Others

Cat.No: T70717

Target: Others

Indinavir, threo-

Cat.No: T25535

Synonym: Threo-indinavir,Indinavir sulfate specified impurity C

Target: Others

Indinavir lactone

Cat.No: T68376

Target: Others

Cat.No: T5863L

Synonym: 茚地那韦,MK-639,L 735 524,Crixivan

Target: Others

Diethylhomospermine

Cat.No: T27171

Synonym: DEHOP,BE-4-4-4,DEHSPM,DE-444

Target: Others

Cat.No: T70147

Target: Others

Peptide T amide

Cat.No: TP2401

Synonym: D-Ala(1)-peptide T amide

Nevirapine hemihydrate

Cat.No: T69796

Target: Others

Hydroxy ritonavir

Cat.No: T74106

Target: Others

ddCTP trisodium

Cat.No: T63602

Target: Others

HIV-1 inhibitor-46

Cat.No: T62690

Target: Others

HIV-1 inhibitor-31

Cat.No: T62070

Target: Others

HIV-1 inhibitor-53

Cat.No: T72568

Target: HIV Protease

Zidovudine diphosphate

Cat.No: T71518

Target: Others

Zidovudine glucuronide

Cat.No: T71983

Target: Others

Fomivirsen sodium

Cat.No: T39068

Target: Others

Cidofovir sodium

Cat.No: T71066

Target: Others

HIV protease-IN-1

Cat.No: T74939

Target: Others

Calcitriol Impurities D

Cat.No: T19228

Synonym: 24-Homo Calcitriol,24-Homo-1,25-dihydroxyvitamin D3

Target: Antiviral

HIV-1 inhibitor-32

Cat.No: T63306

Target: Others

1-Palmitoyl-2-Lauroyl-sn-glycero-3-PC

Cat.No: T84453

Synonym: 1-Palmitoyl-2-Lauroyl-sn-glycero-3-Phosphatidylcholine

Target: Others

[Lys8] Vasopressin Desglycinamide

Cat.No: T83488

Cat.No: T64303

Target: Others

HIV-1 inhibitor-34

Cat.No: T62782

Target: Others

2’-O-Acetyl-5’-O-benzoyl-3’-O-(2-methoxyethyl) uridine

Cat.No: T75232

Target: Others

Cat.No: T75112

Target: Others

HIV-1 inhibitor-33

Cat.No: T62353

Target: Others

Cat.No: T80963

Cat. No.	Product Name	Target	Signaling Pathways
T5748	Ipecoside AIDS031406	Others	Others
	Ipecoside (AIDS031406) 是一种生物碱，分离自Psychotria。
T1284	Megestrol acetate SC10363,醋酸甲地孕酮,BDH1298	Glucocorticoid Receptor; Estrogen/progestogen Receptor; Progesterone Receptor; HIV Protease; Autophagy	Autophagy; Endocrinology/Hormones; Microbiology/Virology; Others; Proteases/Proteasome
	Megestrol acetate (BDH1298) 是具有口服活性的合成孕激素。它还具有抗雄激素特性，可用于治疗厌食症和恶病质。
T1388	Fluconazole 氟康唑,UK-49858	Antibiotic; Antifection; Antifungal	Microbiology/Virology
	Fluconazole (UK-49858) 是一种对多种真菌具有活性的三唑类抗真菌剂，抑制 C. albicans 和 Candida kefyr 的 IC99为 0.20 μg/mL 至 0.39 μg/mL。
T74293	Allolithocholic acid	Others	Others
	Allolithocholic acid 是一种类固醇酸，在正常血清和粪便中可发现。该化合物促进脂肪与甾醇在肠道及肝脏的排泄、吸收与运输。
T2598	Thymopentin TP5,胸腺五肽	Estrogen/progestogen Receptor; Endogenous Metabolite	Endocrinology/Hormones; Metabolism
	Thymopentin (TP5) 是主要由胸腺皮质和髓质上皮细胞分泌的生物特性肽。它能促使自人类胚胎干细胞产生 T 细胞群。它是有效免疫调节剂，具有很短的血浆半衰期(30 秒)。
T2O2733	L-Cystine Cystine Acid,cystine,胱氨酸,L-胱氨酸	Antioxidant; Ferroptosis; Endogenous Metabolite	Apoptosis; Metabolism; oxidation-reduction
	L-Cystine (Cystine Acid) 是一种从半胱氨酸氨基酸硫醇侧链氧化获得的含硫衍生物。它起到抗氧化剂的作用，保护组织免受辐射和污染，减缓衰老过程。它还有助于蛋白质合成。
T4S0797	Berberine 小檗碱,Berberin,Umbellatine,黄连素	Reactive Oxygen Species; Topoisomerase; Endogenous Metabolite; Antibacterial; Antibiotic; Autophagy	Autophagy; DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB
	Berberine (Umbellatine) 属于生物碱类天然产物，可以激活 AMPK、抑制 DNA 拓扑异构酶、诱导 ROS 生成。Berberine 具有抗肿瘤、抗菌、降血糖、降血脂等生物学活性。
TN2115	Pseudohypericin	Others; Prostaglandin Receptor	GPCR/G Protein; Immunology/Inflammation; Others
	Pseudohypericin has photocytotoxic, and antiretroviral activities, it has potential therapeutic value in diseases such as AIDS.
TN7260	Z3-Dodecenyl E2-butenoate	Others	Others
	Z3-Dodecenyl E2-butenoate, a female sex pheromone of the sweet potato weevil (C. formicarius), is utilized for baiting and trapping male sweet potato weevils. This method aids in managing their populations in agricultural fields while minimizing insecticide use.
T3S0804	Worenine 甲基黄连碱,Worenin	Others	Others
	Worenine (Worenin) 是一种从黄连中提取的物质。它在大鼠体内第一阶段代谢中显示出脱氢，氢化，羟基化和脱亚甲基反应。在大鼠体内 II 期代谢中显示为硫酸化和葡萄糖醛酸化反应。
TN4585	Moronic acid	HIV Protease; Antifection; HSV	Microbiology/Virology; Proteases/Proteasome
	Moronic acid shows oral therapeutic efficacy in HSV-infected mice and possessed novel anti-HSV activity. It also shows significant anti-HIV activity (EC(50) 186) and was modified to develop more potent anti-AIDS agents. Moronic acid is a new structural lead for anti-EBV drug development, can substantially reduce the numbers of EBV particles produced by the cells after lytic induction. Morolic and moronic acids have shown sustained antidiabetic and antihyperglycemic action possibly mediated by an...

天然产物

Cat.No: T5748

Synonym: AIDS031406

Target: Others

Megestrol acetate

Cat.No: T1284

Synonym: SC10363,醋酸甲地孕酮,BDH1298

Target: Glucocorticoid Receptor, Estrogen/progestogen Receptor, Progesterone Receptor, HIV Protease, Autophagy

Cat.No: T1388

Synonym: 氟康唑,UK-49858

Target: Antibiotic, Antifection, Antifungal

Allolithocholic acid

Cat.No: T74293

Target: Others

Cat.No: T2598

Synonym: TP5,胸腺五肽

Target: Estrogen/progestogen Receptor, Endogenous Metabolite

Cat.No: T2O2733

Synonym: Cystine Acid,cystine,胱氨酸,L-胱氨酸

Target: Antioxidant, Ferroptosis, Endogenous Metabolite

Cat.No: T4S0797

Synonym: 小檗碱,Berberin,Umbellatine,黄连素

Target: Reactive Oxygen Species, Topoisomerase, Endogenous Metabolite, Antibacterial, Antibiotic, Autophagy

Pseudohypericin

Cat.No: TN2115

Target: Others, Prostaglandin Receptor

Z3-Dodecenyl E2-butenoate

Cat.No: TN7260

Target: Others

Cat.No: T3S0804

Synonym: 甲基黄连碱,Worenin

Target: Others

Cat.No: TN4585

Target: HIV Protease, Antifection, HSV

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPJ-01467	Oncostatin M/OSM Protein, Human, Recombinant (E. coli, His) Oncostatin-M,OSM	Human	E. coli
	Oncostatin M (OSM) is a glycoprotein belonging to the interleukin-6 family of cytokines that includes leukemia-inhibitory factor, granulocyte colony-stimulating factor, and interleukin 6. OSM encodes a growth regulator, which Inhibits the proliferation of a number of tumor cell lines. It stimulates proliferation of AIDS-KS cells. OSM regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. OSM is considered as a pleiotropic cytokine that initiates its biological ac...
TMPH-01509	SPAM1 Protein, Human, Recombinant (His) Sperm adhesion molecule 1,Hyaluronidase PH-20,Sperm surface ...	Human	E. coli
	Involved in sperm-egg adhesion. Upon fertilization sperm must first penetrate a layer of cumulus cells that surrounds the egg before reaching the zona pellucida. The cumulus cells are embedded in a matrix containing hyaluronic acid which is formed prior to ovulation. This protein aids in penetrating the layer of cumulus cells by digesting hyaluronic acid.
TMPJ-01337	IL-21R Protein, Mouse, Recombinant (aa 20-236, His) Nilr,IL-21R,Interleukin-21 receptor,IL-21 receptor,Il21r	Mouse	HEK293 Cells
	Interleukin-21 receptor (IL-21R) is a type I transmembrane glycoprotein within the class I cytokine receptor family, type 4 subfamily. IL-21R is expressed mainly on B cells, NK cells, and activated T cells, but is also found on dendritic cells, alternatively activated macrophages, intestinal lamina propria fibroblasts and epithelial cells, and keratinocytes. Both IL-21 and IL-4 are necessary for efficient B cell IgG1 production and normal germinal center architecture. B cell IL-21 R engagement i...
TMPY-02518	TCL1A Protein, Human, Recombinant (His) TCL1,T-cell leukemia/lymphoma 1A	Human	E. coli
	T-cell leukemia/lymphoma protein 1A (abbreviated for TCL1A) is a member of the TCL1 family. TCL1 protooncogene is expressed in CD3-CD4-CD8-precursor T cells and is extinguished at the CD4+CD8+stage of thymocyte development. In B cells, TCL1 is first expressed in pro-B cells and remains high in naive mantle zone B cells of peripheral lymphoid tissues. The TCL1 protooncogene is overexpressed in many mature B cell lymphomas, especially from AIDS patients. It has been demonstrated that TCL1 is a pow...
TMPJ-00920	CD40 Ligand Protein, Mouse, Recombinant (aa 112-260, His) TNFSF5,Tumor necrosis factor ligand superfamily member 5,CD4...	Mouse	HEK293 Cells
	CD40 Ligand, also known as TNFSF5, CD154, is a type II transmembrane glycoprotein member of the TNF superfamily. Mature mouse CD40 Ligand consists of a 22 amino acid (aa) cytoplasmic domain, a transmembrane segment, and a 214 aa extracellular region. CD40 Ligand is expressed as a homotrimer on platelets and activated T cells and B cells. It is upregulated following stimulation of basophils, eosinophils, fibroblasts, mast cells, monocytes, natural killer cells, vascular endothelial cells, and sm...

重组蛋白

Oncostatin M/OSM Protein, Human, Recombinant (E. coli, His)

Cat.No: TMPJ-01467

Species: Human

Expression System: E. coli

SPAM1 Protein, Human, Recombinant (His)

Cat.No: TMPH-01509

Species: Human

Expression System: E. coli

IL-21R Protein, Mouse, Recombinant (aa 20-236, His)

Cat.No: TMPJ-01337

Species: Mouse

Expression System: HEK293 Cells

TCL1A Protein, Human, Recombinant (His)

Cat.No: TMPY-02518

Species: Human

Expression System: E. coli

CD40 Ligand Protein, Mouse, Recombinant (aa 112-260, His)

Cat.No: TMPJ-00920

Species: Mouse

Expression System: HEK293 Cells

Cat. No.	Product Name	Target	Signaling Pathways
TMID-0205	Nevirapine-d4
	Nevirapine-d4 是 Nevirapine 的氘代化合物。Nevirapine 的 CAS 号为 129618-40-2。Nevirapine 是一种HIV-1逆转录酶非核苷抑制剂，Ki值为 270 μM，可用于研究 HIV/AIDS。
TMID-0206	Nevirapine-d3
	Nevirapine-d3 是 Nevirapine 的氘代化合物。Nevirapine 的 CAS 号为 129618-40-2。Nevirapine 是一种HIV-1逆转录酶非核苷抑制剂，Ki值为 270 μM，可用于研究 HIV/AIDS。
TMID-0081	Fluconazole-d4
	Fluconazole-d4 是 Fluconazole 的氘代化合物。Fluconazole 的 CAS 号为 86386-73-4。Fluconazole是一种对多种真菌具有活性的三唑类抗真菌剂，抑制C. albicans和Candida kefyr的 IC99为 0.20 μg/mL 至 0.39 μg/mL。
TMIJ-0217	Abacavir-d4
	Abacavir-d4 是 Abacavir 的氘代化合物。Abacavir 的 CAS 号为 136470-78-5。Abacavir是一种核苷类似物逆转录酶抑制剂。
TMIJ-0306	Ganciclovir-d5
	Ganciclovir-d5 是 Ganciclovir 的氘代化合物。Ganciclovir 的 CAS 号为 82410-32-0。Ganciclovir是核苷类似物和口服抗病毒药物，对CMV具有抗病毒活性。它用于治疗与艾滋病相关的巨细胞病毒感染的并发症。
TMIJ-0076	Ritonavir-13C-d3
	Ritonavir-13C-d3 是 Ritonavir 的 13C 和氘代化合物。Ritonavir 的 CAS 号为 155213-67-5。Ritonavir 是一种 HIV 蛋白酶抑制剂，可研究 HIV 感染和 AIDS 。它也是SARS-CoV 3CLpro的抑制剂，IC50为 1.61 μM。

同位素标记化合物

Cat.No: TMID-0205

Cat.No: TMID-0206

Cat.No: TMID-0081

Cat.No: TMIJ-0217

Cat.No: TMIJ-0306

Ritonavir-13C-d3

Cat.No: TMIJ-0076

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