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27

抑制剂 & 化合物

31

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T82222	H-D-MeAla-EtVaI-VaI-MeLeu-AIa-D-AIa-MeLeu-MeLeu-MeVaI-MeBmt(OAc)-Abu-O-CH2-CH2-NHMe
	H-D-MeAla-EtVal-Val-MeLeu-AIa-D-AIa-MeLeu-MeLeu-MeVal-MeBmt(OAc)-Abu-O-CH2-CH2-NHMe 是一种非免疫抑制性的环孢菌素A衍生物，具备研究先天性肌营养不良症潜力[1]。
T9622	MF-766	Prostaglandin Receptor	GPCR/G Protein; Immunology/Inflammation
	MF-766 是高效的、具有口服活性的EP4选择性拮抗剂，Ki 为 0.23 nM。它在功能检测中表现为一种完整的拮抗剂，其 IC50为 1.4 nM (在 10% HS 存在时变成 1.8 nM)。它具有用于癌症和炎症疾病研究的价值。
T2125	Trametinib GSK1120212,曲美替尼,JTP-74057	Apoptosis; MEK; Autophagy	Apoptosis; Autophagy; MAPK
	Trametinib (GSK1120212) 是一种 MEK 抑制剂，抑制 MEK1 和 MEK2 (IC50=0.7/0.9 nM)，具有 ATP 非竞争性和口服活性。Trametinib 可以激活自噬，诱导凋亡。
T5857	Trametinib (DMSO solvate) Trametinib DMSO solvate,GSK-1120212 (DMSO solvate),Trametinib dimethyl sulfoxide,JTP-74057 (DMSO solvate)	Apoptosis; MEK	Apoptosis; MAPK
	Trametinib (DMSO solvate) (GSK-1120212 (DMSO solvate)) 是一种口服有效的 MEK 抑制剂，抑制 MEK1 和 MEK2 的 IC50分别为 2 nM。它还能激活自噬，诱导凋亡。
T11506	Guaiapate Mg 5454,Klamar	Others	Others
	Guaiapate 具有止咳镇静作用。
T84310	Guaiacylglycerol-beta-guaiacyl Ether	Others	Others
	Guaiacylglycerol-beta-guaiacyl Ether 可被微生物降解，常用作模拟微生物降解木质素活植物细胞壁的底物。
T3267	Potassium guaiacolsulfonate hemihydrate 愈创木酚磺酸钾水合物,Potassium guaiacolsulfonate,Potassium 4-guaiacolsulfonate hemihydrate,愈创木酚磺酸钾	Antibacterial; Antibiotic	Microbiology/Virology
	Potassium guaiacolsulfonate hemihydrate (Potassium guaiacolsulfonate) 是一种芳香族磺酸，在医药中用作祛痰剂，可治疗急性呼吸道感染。它可松弛粘液，与其他药物合用，可治疗普通感冒、感染或过敏引起的咳嗽。
T0284	Sulfogaiacol guaiacolsulfonate,愈创木酚磺酸钾	Others; Antibacterial	Microbiology/Virology; Others
	Sulfogaiacol (guaiacolsulfonate) 是一种镇咳剂，可研究急性呼吸道感染。
T124616	Furoguaiaoxidin	Others	Others
	Furoguaiaoxidin 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T124616，CAS号为 58096-91-6。
T126147	Di-O-demethylisoguaiacin	Others	Others
	Di-O-demethylisoguaiacin 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T126147，CAS号为 125074-14-8。
T124764	Guaiaretic acid	Others	Others
	Guaiaretic acid 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T124764，CAS号为 500-40-3。
T125992	threo-Guaiacylglycerol β-dihydroconiferyl ether	Others	Others
	threo-Guaiacylglycerol β-dihydroconiferyl ether 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T125992。
T125621	erythro-Guaiacylglycerol β-coniferyl ether	Others	Others
	erythro-Guaiacylglycerol β-coniferyl ether 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T125621。
T32015	Guaiacyl acetate NSC-3831,NSC 3831,NSC3831	Others	Others
	Guaiacyl acetate is a biochemical.
T126154	(-)-Dihydroguaiaretic acid	Others	Others
	(-)-Dihydroguaiaretic acid 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T126154。
T40125	4,5-Dichloroguaiacol	Others	Others
	4,5-Dichloroguaiacol is the major component of chlorinated phenol.
T124473	threo-Guaiacylglycerol-beta-coniferyl aldehyde ether	Others	Others
	threo-Guaiacylglycerol-beta-coniferyl aldehyde ether 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T124473。
T126216	1α,7α,10αH-Guaia-4,11-dien-3-one	Others	Others
	1α,7α,10αH-Guaia-4,11-dien-3-one 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T126216。
T21072	4-Aminoguaiacol	Others	Others
	4-Aminoguaiacol is a bioactive chemical.
T36594	4-Chloroguaiacol	Others	Others
	4-Chloroguaiaco (4-Chloro-2-methoxyphenol) is a phenol derivative, with antimicrobial activity. 4-Chloroguaiaco shows inhibition against S. aureus and E. coli with MICs of both 110 μg/mL[1]. [1]. Patrícia Fontes Pinheiro, et al. Semisynthetic Phenol Derivatives Obtained from Natural Phenols: Antimicrobial Activity and Molecular Properties. J Agric Food Chem. 2018 Jan 10;66(1):323-330.
T124284	Erythro-Guaiacylglycerol-beta-coniferyl aldehyde ether	Others	Others
	Erythro-Guaiacylglycerol-beta-coniferyl aldehyde ether 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T124284。
T40655	3,4,5-Trichloroguaiacol	Others	Others
	3,4,5-Trichloroguaiacol is a phenolic compound that is commonly found in the effluents originating from bleached kraft pulp mills.
T39145	4,6-Dichloroguaiacol	Others	Others
	4,6-Dichloroguaiacol elicits biochemical and morphological alterations in human peripheral blood lymphocytes in vitro.
T40180	Tetrachloroguaiacol	Others	Others
	Tetrachloroguaiacol, the predominant chlorinated phenol, is generated through the chlorine bleaching process of wood pulp.
T60493	Guaiacol Carbonate	Others	Others
	Guaiacol Carbonate 是一种祛痰剂，其作用是通过胃的反射作用，通过胃神经到达延髓中枢，然后再通过外周进入呼吸道，从而起到祛痰作用。
T40299	4,5,6-Trichloroguaiacol	Others	Others
	4,5,6-Trichloroguaiacol is a phenolic compound that is commonly found in the effluents generated by bleached kraft pulp mills.
T31215	DB-766 DB766	Others	Others
	DB-766 is a potential chemotherapeutic candidate for Chagas' disease treatment. DB-766 exhibits strong trypanocidal activity and excellent selectivity for bloodstream trypomastigotes and intracellular amastigotes (Y strain), giving IC(50)s of 60 and 25 nM

化合物

H-D-MeAla-EtVaI-VaI-MeLeu-AIa-D-AIa-MeLeu-MeLeu-MeVaI-MeBmt(OAc)-Abu-O-CH2-CH2-NHMe

Cat.No: T82222

Cat.No: T9622

Target: Prostaglandin Receptor

Cat.No: T2125

Synonym: GSK1120212,曲美替尼,JTP-74057

Target: Apoptosis, MEK, Autophagy

Trametinib (DMSO solvate)

Cat.No: T5857

Synonym: Trametinib DMSO solvate,GSK-1120212 (DMSO solvate),Trametinib dimethyl sulfoxide,JTP-74057 (DMSO solvate)

Target: Apoptosis, MEK

Cat.No: T11506

Synonym: Mg 5454,Klamar

Target: Others

Guaiacylglycerol-beta-guaiacyl Ether

Cat.No: T84310

Target: Others

Potassium guaiacolsulfonate hemihydrate

Cat.No: T3267

Synonym: 愈创木酚磺酸钾水合物,Potassium guaiacolsulfonate,Potassium 4-guaiacolsulfonate hemihydrate,愈创木酚磺酸钾

Target: Antibacterial, Antibiotic

Cat.No: T0284

Synonym: guaiacolsulfonate,愈创木酚磺酸钾

Target: Others, Antibacterial

Furoguaiaoxidin

Cat.No: T124616

Target: Others

Di-O-demethylisoguaiacin

Cat.No: T126147

Target: Others

Guaiaretic acid

Cat.No: T124764

Target: Others

threo-Guaiacylglycerol β-dihydroconiferyl ether

Cat.No: T125992

Target: Others

erythro-Guaiacylglycerol β-coniferyl ether

Cat.No: T125621

Target: Others

Guaiacyl acetate

Cat.No: T32015

Synonym: NSC-3831,NSC 3831,NSC3831

Target: Others

(-)-Dihydroguaiaretic acid

Cat.No: T126154

Target: Others

4,5-Dichloroguaiacol

Cat.No: T40125

Target: Others

threo-Guaiacylglycerol-beta-coniferyl aldehyde ether

Cat.No: T124473

Target: Others

1α,7α,10αH-Guaia-4,11-dien-3-one

Cat.No: T126216

Target: Others

4-Aminoguaiacol

Cat.No: T21072

Target: Others

4-Chloroguaiacol

Cat.No: T36594

Target: Others

Erythro-Guaiacylglycerol-beta-coniferyl aldehyde ether

Cat.No: T124284

Target: Others

3,4,5-Trichloroguaiacol

Cat.No: T40655

Target: Others

4,6-Dichloroguaiacol

Cat.No: T39145

Target: Others

Tetrachloroguaiacol

Cat.No: T40180

Target: Others

Guaiacol Carbonate

Cat.No: T60493

Target: Others

4,5,6-Trichloroguaiacol

Cat.No: T40299

Target: Others

Cat.No: T31215

Synonym: DB766

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
TN6034	Aristolactam AIa
	Aristolactam AIa 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN6034，CAS号为 97399-90-1。
TJS2190	Nordihydroguaiaretic acid 去甲二氢愈创木酸,NDGA,Dihydronorguaiaretic Acid	Antioxidant; Ferroptosis; Lipoxygenase; Autophagy	Apoptosis; Autophagy; Metabolism; oxidation-reduction
	Nordihydroguaiaretic acid (NDGA) 是从极叉开拉瑞阿提取出的一种天然产物，是脂氧合酶抑制剂，具有抗氧化和清除自由基的特性。
T1301	Guaiacol O-methylcatechol,2-hydroxyanisole,o-methoxyphenol,2-Methoxyphenol,愈创木酚	NF-κB; COX; Endogenous Metabolite	Immunology/Inflammation; Metabolism; Neuroscience; NF-κB
	Guaiacol (2-Methoxyphenol) 是从小叶栲中提取的一种酚类，可抑制 LPS 刺激的COX-2表达和NF-κB 激活，具有抗炎活性。
T3159	Guaiazulene 愈创奥,azulon,Vetivazulen,愈疮奥,Eucazulen	Others; Endogenous Metabolite	Metabolism; Others
	Guaiazulene (azulon) 存在于几种药用植物和芳香植物精油中，具有抗氧化特性，对神经元和 N2a-NB 细胞有体外细胞毒特性。
TN1581	Dihydroguaiaretic acid 二氢愈创木酸	COX; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Immunology/Inflammation; Neuroscience
	Dihydroguaiaretic acid has antioxidative activity, can significantly protect primary cultured neuronal cells against glutamate-induced oxidative stress.
T28021	meso-Dihydroguaiaretic acid
	meso-Dihydroguaiaretic acid is an LXR-α antagonist, it inhibits hepatic lipid accumulation by activating AMP-activated protein kinase in human HepG2 cells.
T81701	Nardoguaianone K 10-epi-Nardoguaianone J
	Nardoguaianone K，一种从Nardostachys chinensis根中分离得到的愈创木脂类化合物，用于胰腺癌研究。
T75530	Nardoguaianone J	Others	Others
	Nardoguaianone J，一种愈创木脂类化合物，可从Nardostachys chinensis 的根中分离得到。Nardoguaianone J 可提高SERT 活性。
TN4006	erythro-Guaiacylglycerol beta-sinapyl ether 7-O-glucoside	Others	Others
	erythro-Guaiacylglycerol beta-sinapyl ether 7-O-glucoside 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN4006，CAS号为 412029-03-9。
TN4003	Erythro-Guaiacylglycerol beta-coniferyl ether	Glucosidase	Metabolism
	Erythro-Guaiacylglycerol beta-coniferyl ether 可以从绿豆的茎和叶中提取出来的化合物，对 α-糖苷酶有抑制作用，EC50 值为 18.71 μM。
TN5145	threo-Guaiacylglycerol	Others	Others
	threo-Guaiacylglycerol 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN5145，CAS号为 27391-16-8。
TN1284	4β,12-Dihydroxyguaian-6,10-diene 4beta,12-dihydroxyguaian-6,10-diene	Others	Others
	4beta,12-dihydroxyguaian-6,10-diene is a natural product from Alisma orientale.
T13716	(+)-Guaiacin	Others	Others
	(+)-Guaiacin is a compound isolated from the bark of Machilus wangchiana Chun. It shows potent in vitro activities against the release of β-glucuronidase in rat polymorphonuclear leukocytes (PMNs) induced by platelet-activating factor (PAF).
TN6817	1αH,5αH-guaia-6-ene-4β,10β-diol
	1αH,5αH-guaia-6-ene-4β,10β-diol is a natural product.
TN5421	threo-Guaiacylglycerol-β-O-4'-dehydrodisinapyl ether
	threo-Guaiacylglycerol-β-O-4'-dehydrodisinapyl ether 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN5421，CAS号为 844637-85-0。
TN4007	erythro-Guaiacylglycerol beta-sinapyl ether	Others	Others
	erythro-Guaiacylglycerol beta-sinapyl ether是一种天然产物，属于忍冬科接骨木属，其产品编号为 TN4007，CAS号为 877875-96-2。erythro-Guaiacylglycerol beta-sinapyl ether可用作对照参考。
TN6585	2-Methoxyfuranoguaia-9-ene-8-one
	2-Methoxyfuranoguaia-9-ene-8-one 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN6585，CAS号为 88010-62-2。
TN5416	threo-7-O-Methylguaiacylglycerol β-coniferyl ether
	threo-7-O-Methylguaiacylglycerol β-coniferyl ether 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN5416，CAS号为 150333-85-0。
T82441	Erythro-guaiacylglycerol-β-ferulic acid ether
	Erythro-guaiacylglycerol-β-ferulic acid ether为Gueldenstaedtia verna中分离得到的天然产物。
TN4008	erythro-Guaiacylglycerol	Others	Others
	erythro-Guaiacylglycerol是一种天然产物，属于杜仲科杜仲属，其产品编号为 TN4008，CAS号为 38916-91-5。erythro-Guaiacylglycerol可用作对照参考。
TN4246	Ifflaiamine	Others	Others
	Ifflaiamine is a natural product from Flindersia ifflaiana F. Muell.
TN4004	Erythro-Guaiacylglycerol β-dihydroconiferyl ether
	Erythro-Guaiacylglycerol β-dihydroconiferyl ether 是从加拿大枫糖浆中提取的，具有潜在的抗氧化活性，可用于研究营养保健品。
TN4005	erythro-Guaiacylglycerol-beta-O-4'-dehydrodisinapyl ether	Serine Protease	Proteases/Proteasome
	erythro-Guaiacylglycerol-beta-O-4'-dehydrodisinapyl ether 是一种从巴西橡胶种子壳中提取的化合物，对人白细胞弹性蛋白酶具有抑制活性（IC50 ：171 umol/L）。
TN3794	Dehydroaglaiastatin	Others	Others
	Dehydroaglaiastatin是一种天然产物，属于楝科米仔兰属，其产品编号为 TN3794，CAS号为 155595-93-0。Dehydroaglaiastatin可用作对照参考。
TN2948	3'-Hydroxydehydroaglaiastatin	Others	Others
	3'-Hydroxydehydroaglaiastatin 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN2948，CAS号为 259143-58-3。
T5525	Shiraiachrome A
	Shiraiachrome A 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 T5525，CAS号为 124709-39-3。
T82031	Isoguaiacin
	Isoguaiacin为一种天然产物，具有复杂的多环化合物结构，广泛应用于生物医药研究领域。
TN5406	threo-Guaiacylglycerol β-coniferyl ether
	Threo-Guaiacylglycerol beta-coniferyl ether displays significant inhibitory effects on NO production.
TN2665	1alpha,4beta,10beta-Trihydroxyguaia-2,11(13)-dien-12,6alpha-olide	Others	Others
	1alpha,4beta,10beta-Trihydroxyguaia-2,11(13)-dien-12,6alpha-olide是一种天然产物，属于泽泻科泽泻属，其产品编号为 TN2665，CAS号为 221148-94-3。1alpha,4beta,10beta-Trihydroxyguaia-2,11(13)-dien-12,6alpha-olide可用作对照参考。
T3888	Scopolin Murrayin,东莨菪甙,Scopoloside,东莨菪苷	Sirtuin	Chromatin/Epigenetic; DNA Damage/DNA Repair
	Scopolin (Scopoloside) 是从拟南芥根中分离出来的香豆素，可通过激活SIRT1介导的信号级联反应减轻了肝脂肪变性。
T78492	D-Mannuronic acid sodium	Others	Others
	D-Mannuronic acid sodium，一种可从Macrocystis pyrifera中分离得到的化合物，显示出在自身免疫性脑脊髓炎(EAE)、佐剂性关节炎(AIA)、肾病综合征以及急性肾小球肾炎的研究中具有潜在应用价值。

天然产物

Aristolactam AIa

Cat.No: TN6034

Nordihydroguaiaretic acid

Cat.No: TJS2190

Synonym: 去甲二氢愈创木酸,NDGA,Dihydronorguaiaretic Acid

Target: Antioxidant, Ferroptosis, Lipoxygenase, Autophagy

Cat.No: T1301

Synonym: O-methylcatechol,2-hydroxyanisole,o-methoxyphenol,2-Methoxyphenol,愈创木酚

Target: NF-κB, COX, Endogenous Metabolite

Cat.No: T3159

Synonym: 愈创奥,azulon,Vetivazulen,愈疮奥,Eucazulen

Target: Others, Endogenous Metabolite

Dihydroguaiaretic acid

Cat.No: TN1581

Synonym: 二氢愈创木酸

Target: COX, DNA/RNA Synthesis

meso-Dihydroguaiaretic acid

Cat.No: T28021

Nardoguaianone K

Cat.No: T81701

Synonym: 10-epi-Nardoguaianone J

Nardoguaianone J

Cat.No: T75530

Target: Others

erythro-Guaiacylglycerol beta-sinapyl ether 7-O-glucoside

Cat.No: TN4006

Target: Others

Erythro-Guaiacylglycerol beta-coniferyl ether

Cat.No: TN4003

Target: Glucosidase

threo-Guaiacylglycerol

Cat.No: TN5145

Target: Others

4β,12-Dihydroxyguaian-6,10-diene

Cat.No: TN1284

Synonym: 4beta,12-dihydroxyguaian-6,10-diene

Target: Others

Cat.No: T13716

Target: Others

1αH,5αH-guaia-6-ene-4β,10β-diol

Cat.No: TN6817

threo-Guaiacylglycerol-β-O-4'-dehydrodisinapyl ether

Cat.No: TN5421

erythro-Guaiacylglycerol beta-sinapyl ether

Cat.No: TN4007

Target: Others

2-Methoxyfuranoguaia-9-ene-8-one

Cat.No: TN6585

threo-7-O-Methylguaiacylglycerol β-coniferyl ether

Cat.No: TN5416

Erythro-guaiacylglycerol-β-ferulic acid ether

Cat.No: T82441

erythro-Guaiacylglycerol

Cat.No: TN4008

Target: Others

Cat.No: TN4246

Target: Others

Erythro-Guaiacylglycerol β-dihydroconiferyl ether

Cat.No: TN4004

erythro-Guaiacylglycerol-beta-O-4'-dehydrodisinapyl ether

Cat.No: TN4005

Target: Serine Protease

Dehydroaglaiastatin

Cat.No: TN3794

Target: Others

3'-Hydroxydehydroaglaiastatin

Cat.No: TN2948

Target: Others

Shiraiachrome A

Cat.No: T5525

Cat.No: T82031

threo-Guaiacylglycerol β-coniferyl ether

Cat.No: TN5406

1alpha,4beta,10beta-Trihydroxyguaia-2,11(13)-dien-12,6alpha-olide

Cat.No: TN2665

Target: Others

Cat.No: T3888

Synonym: Murrayin,东莨菪甙,Scopoloside,东莨菪苷

Target: Sirtuin

D-Mannuronic acid sodium

Cat.No: T78492

Target: Others

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