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Search Results for " ag-18 "

Targets Recommended: EGFR

4

抑制剂 & 化合物

7

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T2063	Tyrphostin 23 RG-50810,TX 825,Tyrphostin A23,AG18	EGFR	Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	Tyrphostin 23 (AG18) 是一种EGFR 抑制剂，IC50值为35 μM。
T21128	Lansoprazole sulfide Lansoprazole impurity C,AG-1777,EC 600-451-9,H 225/18,K-1252	Others	Others
	Lansoprazole sulfide is an impurity of Lansoprazole, which is a gastric pump inhibitor.
T69196	AG-012986	Others	Others
	AG-012986 is a multitargeted cyclin-dependent kinase (CDK) inhibitor active against CDK1, CDK2, CDK4/6, CDK5, and CDK9, with selectivity over a diverse panel of non-CDK kinases. AG-012986 showed antiproliferative activities in vitro with IC(50)s of <100 nmol/L in 14 of 18 tumor cell lines. In vivo, significant antitumor efficacy induced by AG-012986 was seen (tumor growth inhibition, >83.1%) in 10 of 11 human xenograft tumor models. AG-012986 also showed dose-dependent retinoblastoma Ser(795) hy...
T69197	AG-012986 HCl	Others	Others
	AG-012986 HCl is a multitargeted cyclin-dependent kinase (CDK) inhibitor active against CDK1, CDK2, CDK4/6, CDK5, and CDK9, with selectivity over a diverse panel of non-CDK kinases. AG-012986 HCl showed antiproliferative activities in vitro with IC(50)s of <100 nmol/L in 14 of 18 tumor cell lines. In vivo, significant antitumor efficacy induced by AG-012986 HCl was seen (tumor growth inhibition, >83.1%) in 10 of 11 human xenograft tumor models. AG-012986 HCl also showed dose-dependent retinoblas...

化合物

Cat.No: T2063

Synonym: RG-50810,TX 825,Tyrphostin A23,AG18

Target: EGFR

Lansoprazole sulfide

Cat.No: T21128

Synonym: Lansoprazole impurity C,AG-1777,EC 600-451-9,H 225/18,K-1252

Target: Others

Cat.No: T69196

Target: Others

Cat.No: T69197

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-04205	AGR3 Protein, Human, Recombinant (mFc) hAG-3,AG3,HAG3,anterior gradient ...	Human	HEK293 Cells
	Anterior gradient protein (AGR) 3 is a highly related homologue of pro-oncogenic AGR2 and belongs to the family of protein disulfide isomerases. AGR3 was found in breast, ovary, prostate, and liver cancer, it is associated with the level of differentiation, slowly proliferating tumors, and more favorable prognosis of breast cancer patients. AGR3 is a specialized member of the PDI family that plays an unexpected role in the regulation of CBF and mucociliary clearance in the airway. AGR3 had been...
TMPK-00076	IL-18 Protein (Primary Amine Labeling), Human, Recombinant, Biotinylated 白介素,IL-18,白细胞介素,IL18,IL-1F4,IL-1g,IL1F4,IL...	Human	E. coli
	Interleukin (IL)-18 was originally discovered as a factor that enhanced IFN-γ production from anti-CD3-stimulated Th1 cells, especially in the presence of IL-12. Upon stimulation with Ag plus IL-12, naïve T cells develop into IL-18 receptor (IL-18R) expressing Th1 cells, which increase IFN-γ production in response to IL-18 stimulation.
TMPK-00316	IL-18R alpha Protein, Human, Recombinant (His & Avi) CD218a,IL-18 R1,IL1RRP,IL-18Ra,IL...	Human	HEK293 Cells
	Interleukin-18 (IL-18) is a member of the interleukin-1 family of cytokines produced constitutively by different cell types and by adipose tissue. Interleukin (IL)-18 was originally discovered as a factor that enhanced IFN-γ production from anti-CD3-stimulated Th1 cells, especially in the presence of IL-12. Upon stimulation with Ag plus IL-12, naïve T cells develop into IL-18 receptor (IL-18R) expressing Th1 cells, which increase IFN-γ production in response to IL-18 stimulation. IL-18R alpha Pr...
TMPK-00512	IL-18R alpha Protein, Cynomolgus, Recombinant (aa 22-329, His) IL18R1,IL-1 Rrp,CD218a,IL18Ra,IL-...	Cynomolgus	HEK293 Cells
	Interleukin-18 (IL-18) is a member of the interleukin-1 family of cytokines produced constitutively by different cell types and by adipose tissue. Interleukin (IL)-18 was originally discovered as a factor that enhanced IFN-γ production from anti-CD3-stimulated Th1 cells, especially in the presence of IL-12. Upon stimulation with Ag plus IL-12, naïve T cells develop into IL-18 receptor (IL-18R) expressing Th1 cells, which increase IFN-γ production in response to IL-18 stimulation. IL-18R alpha Pr...
TMPK-00317	IL-18R alpha Protein, Human, Recombinant (His & Avi), Biotinylated IL-18 R α,IL-1 R5,IL18Ra,IL-18Ra,...	Human	HEK293 Cells
	Interleukin-18 (IL-18) is a member of the interleukin-1 family of cytokines produced constitutively by different cell types and by adipose tissue. Interleukin (IL)-18 was originally discovered as a factor that enhanced IFN-γ production from anti-CD3-stimulated Th1 cells, especially in the presence of IL-12. Upon stimulation with Ag plus IL-12, naïve T cells develop into IL-18 receptor (IL-18R) expressing Th1 cells, which increase IFN-γ production in response to IL-18 stimulation. IL-18R alpha Pr...
TMPY-03400	DCBLD1 Protein, Human, Recombinant (His) dJ94G16.1,discoidin, CUB and LCCL domain containing 1,RP1-94...	Human	HEK293 Cells
	Discoidin, also known as DCBLD1, contains 1 CUB domain, 1 F5/8 type C domain and 1 LCCL domain. It is a 715 amino acid single-pass membrane protein. Discoidin has a discoidin I-like domain which shares a common C-terminal region of about 110 amino acids with the FA58C domain, but whose N-terminal 40 amino acids are much less conserved. Discoidin gene contains 31 distinct gt-ag introns. Transcription produces 18 different mRNAs, 16 alternatively spliced variants and 2 unspliced forms. Discoidin i...
TMPJ-01028	Claudin-18.2 Protein, Human, Recombinant (Twin strep & Flag) Claudin 18.2,CLDN18,Claudin-18,CL...	Human	HEK293 Cells
	Claudin-18 (CLDN18) is a protein that in humans is encoded by the CLDN18 gene. It belongs to the group of claudins. CLDN18 belongs to the large claudin family of proteins, which form tight junction strands in epithelial cells. CLDN18 plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. CLDN18 has two isoform A1 and isoform A2. Human CLDN18.2 is highly expressed in a signifcant proportion of gastric and pancreat...

重组蛋白

AGR3 Protein, Human, Recombinant (mFc)

Cat.No: TMPY-04205

Species: Human

Expression System: HEK293 Cells

IL-18 Protein (Primary Amine Labeling), Human, Recombinant, Biotinylated

Cat.No: TMPK-00076

Species: Human

Expression System: E. coli

IL-18R alpha Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00316

Species: Human

Expression System: HEK293 Cells

IL-18R alpha Protein, Cynomolgus, Recombinant (aa 22-329, His)

Cat.No: TMPK-00512

Species: Cynomolgus

Expression System: HEK293 Cells

IL-18R alpha Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00317

Species: Human

Expression System: HEK293 Cells

DCBLD1 Protein, Human, Recombinant (His)

Cat.No: TMPY-03400

Species: Human

Expression System: HEK293 Cells

Claudin-18.2 Protein, Human, Recombinant (Twin strep & Flag)

Cat.No: TMPJ-01028

Species: Human

Expression System: HEK293 Cells

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