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Search Results for " adp-ribosyltransferase "

Targets Recommended: PARP

4

抑制剂 & 化合物

24

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T50098	TIQ-A	PARP	Chromatin/Epigenetic; DNA Damage/DNA Repair
	TIQ-A 是一种 PARP1 抑制剂，通过碱基切除修复途径参与 DNA 单链断裂修复。 PARP1 由 DNA 损伤触发，其过度激活已被认为是许多病理状况的致病因素，包括缺血和再灌注损伤、哮喘相关炎症和动脉粥样硬化形成。
T73007	PARP10-IN-2	PARP	Chromatin/Epigenetic; DNA Damage/DNA Repair
	PARP10-IN-2 是一种有效的单-ADP-核糖基转移酶 PARP10 抑制剂，对人 PARP10 的 IC50 值为 3.64 μM。PARP10-IN-2 对 PARP2 和 PARP15也具有抑制作用， IC50 分别为 27 μM 和 11 μM。
T82965	ARTD3/PARP3-IN-1	Others	Others
	ARTD3/PARP3-IN-1为ARTD3/PARP3的非选择性抑制剂，作用于白喉毒素样ADP-核糖基转移酶3（ARTD3）。
T68714	Iobenguane I 131	Others	Others
	Iobenguane I 131 is a guanidine analog with specific affinity for tissues of the sympathetic nervous system and related tumors. The radiolabeled forms are used as antineoplastic agents and radioactive imaging agents. MIBG serves as a neuron-blocking agent which has a strong affinity for, and retention in, the adrenal medulla and also inhibits ADP-ribosyltransferase.

化合物

Cat.No: T50098

Target: PARP

Cat.No: T73007

Target: PARP

ARTD3/PARP3-IN-1

Cat.No: T82965

Target: Others

Iobenguane I 131

Cat.No: T68714

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-04209	ART1 Protein, Cynomolgus, Recombinant (His) ADP-ribosyltransferase 1	Cynomolgus	HEK293 Cells
	ART1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.7 kDa and the accession number is A0A2K5WCR3.
TMPH-01881	PARP2 Protein, Human, Recombinant (GST & His) Protein poly-ADP-ribosyltransferase PARP2,...	Human	Baculovirus Insect Cells
	PARP2 Protein, Human, Recombinant (GST & His) is expressed in Baculovirus insect cells with N-GST and C-6xHis tag. The predicted molecular weight is 92.8 kDa and the accession number is Q9UGN5.
TMPY-03386	ART3 Protein, Human, Recombinant (His) ADP-ribosyltransferase 3,ARTC3	Human	HEK293 Cells
	ART3 is an arginine-specific ADP-ribosyltransferase which belongs to the Arg-specific ADP-ribosyltransferase family. ART3 catalyzes a reversible reaction which modifies proteins by the addition or removal of ADP-ribose to an arginine residue to regulate the function of the modified protein. It is expressed specifically in testis. ART3 pseudogene is located on chromosome 11. ART3 was identified as a susceptibility gene for non-obstructive azoospermia (NOA). It is a novel therapeutic target in the...
TMPH-01880	PARP2 Protein, Human, Recombinant (His) Protein poly-ADP-ribosyltransferase PARP2,...	Human	E. coli
	PARP2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 72.2 kDa and the accession number is Q9UGN5.
TMPY-03777	ART4/CD297 Protein, Cynomolgus, Recombinant (His) ADP-ribosyltransferase 4 (Dombrock blood g...	Cynomolgus	HEK293 Cells
	ART4/CD297 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 29.1 kDa and the accession number is G7PJY0.
TMPY-03312	ART4/CD297 Protein, Rat, Recombinant (His) ADP-ribosyltransferase 4 (Dombrock blood g...	Rat	HEK293 Cells
	ART4/CD297 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.4 kDa and the accession number is F1MA10.
TMPY-03544	ART4/CD297 Protein, Cynomolgus, Recombinant (hFc) ADP-ribosyltransferase 4 (Dombrock blood g...	Cynomolgus	HEK293 Cells
	ART4/CD297 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 54.7 kDa and the accession number is G7PJY0.
TMPH-01945	TIPARP Protein, Human, Recombinant (His) ADP-ribosyltransferase diphtheria toxin-li...	Human	Baculovirus Insect Cells
	TIPARP Protein, Human, Recombinant (His) is expressed in Baculovirus.
TMPH-01879	PARP11 Protein, Human, Recombinant (His) PARP11,Poly [ADP-ribose] polymerase 11,Protein mono...	Human	E. coli
	Mono-ADP-ribosyltransferase that mediates mono-ADP-ribosylation of target proteins. Plays a role in nuclear envelope stability and nuclear remodeling during spermiogenesis. PARP11 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 41.0 kDa and the accession number is Q9NR21.
TMPH-01944	PARP9 Protein, Human, Recombinant (His & Myc) Poly [ADP-ribose] polymerase 9,ADP-rib...	Human	HEK293 Cells
	PARP9 Protein, Human, Recombinant (His & Myc) is expressed in HEK293.
TMPH-01942	PARP14 Protein, Human, Recombinant (His & Myc) Protein mono-ADP-ribosyltransferase PARP14...	Human	HEK293 Cells
	PARP14 Protein, Human, Recombinant (His & Myc) is expressed in HEK293.
TMPH-01882	PARP9 Protein, Human, Recombinant (His) PARP9,Poly [ADP-ribose] polymerase 9,ADP-<...	Human	E. coli
	PARP9 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 30.0 kDa and the accession number is Q8IXQ6.
TMPH-01943	PARP4 Protein, Human, Recombinant (His) Poly [ADP-ribose] polymerase 4,ADP-rib...	Human	E. coli
	PARP4 Protein, Human, Recombinant (His) is expressed in E. coli.
TMPY-02822	ART4/CD297 Protein, Mouse, Recombinant (hFc) 4432404K01Rik,DOK1,ADP-ribosyltransferase ...	Mouse	HEK293 Cells
	ART4/CD297 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 53.7 kDa and the accession number is Q9CRA0.
TMPH-00432	Diphtheria toxin Protein, Corynephage omega, Recombinant (His & Myc) Diphtheria toxin,DT,NAD(+)--diphthamide ADP-rib...	Corynephage omega	E. coli
	Diphtheria toxin Protein, Corynephage omega, Recombinant (His & Myc) is expressed in E. coli.
TMPH-01941	PARP12 Protein, Human, Recombinant (His & Myc) Protein mono-ADP-ribosyltransferase PARP12...	Human	E. coli
	PARP12 Protein, Human, Recombinant (His & Myc) is expressed in E. coli.
TMPY-06532	ART1 Protein, Human, Recombinant (His) ADP-ribosyltransferase 1,CD296,ARTC1,ART2,...	Human	HEK293 Cells
	ART1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.55 kDa and the accession number is NP_004305.2.
TMPH-03168	Exotoxin A Protein, Pseudomonas aeruginosa, Recombinant (His & KSI) NAD(+)--diphthamide ADP-ribosyltransferase...	Pseudomonas aeruginosa	E. coli
	An NAD-dependent ADP-ribosyltransferase (ADPRT). Catalyzes the transfer of the ADP ribosyl moiety of oxidized NAD (NAD(+)) onto eukaryotic elongation factor 2 (eEF-2) thus arresting protein synthesis. Has an LD(50) of 65 ng/ml against the human lung epithelial cell line C38. Exotoxin A Protein, Pseudomonas aeruginosa, Recombinant (His & KSI) is expressed in E. coli expression system with N-6xHis-KSI tag. The predicted molecular weight is 39.9 kDa and the accession number is P11439.
TMPY-02738	ART4/CD297 Protein, Mouse, Recombinant (His) ADP-ribosyltransferase 4 (Dombrock blood g...	Mouse	HEK293 Cells
	ART4/CD297 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.2 kDa and the accession number is EDL10575.1.
TMPH-03026	CARDS Protein, Mycoplasma pneumoniae, Recombinant (His & Myc) ADP-ribosylating toxin CARDS,CARDX TX,ADP-...	Mycoplasma pneumoniae	E. coli
	Acts as an ADP-ribosylating toxin, which may transfer the ADP-ribosyl group from NAD(+) to specific amino acids in target proteins. Elicits cytopathic effects in mammalian cells, such as disorganization and disruption of respiratory epithelial integrity in tracheal epithelium and vacuolization in the cytoplasm of CHO and HeLa cells.
TMPH-00207	PTX S1 Protein, Bordetella pertussis, Recombinant (His) Islet-activating protein S1,Pertussis toxin subunit 1,NAD-de...	Bordetella pertussis	P. pastoris (Yeast)
	S1 is an NAD-dependent ADP-ribosyltransferase, which plays a crucial role in the pathogenesis of B.pertussis causing disruption of normal host cellular regulation. It catalyzes the ADP-ribosylation of a cysteine in the alpha subunit of host heterotrimeric G proteins. In the absence of G proteins it also catalyzes the cleavage of NAD(+) into ADP-ribose and nicotinamide. It irreversibly uncouples the G-alpha GTP-binding proteins from their membrane receptors. PTX S1 Protein, Bordetella pertussis, ...
TMPH-01742	SIRT6 Protein, Human, Recombinant (GST) Protein mono-ADP-ribosyltransferase sirtui...	Human	E. coli
	SIRT6 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 66.0 kDa and the accession number is Q8N6T7.
TMPY-03868	ARF5 Protein, Human, Recombinant (His) ARF5,ADP ribosylation factor 5	Human	E. coli
	ARF5, also known as ADP-ribosylation factor 5, belongs to the small GTPase superfamily, Arf family. Members of this family stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. ARF5 functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. ARF5 Is involved in protein trafficking. ARF5 may also modulate vesicle budding and uncoating within the Golgi apparatus.
TMPY-03796	ARF3 Protein, Human, Recombinant (His) ADP-ribosylation factor 3	Human	E. coli
	ARF3, also known as ADP-ribosylation factor 3, belongs to the RAS superfamily. Members of this family include ARF1, ARF2, ARF3, ARF4, ARF5 and ARF6. ARF3 gene is a member of the human ARF gene family. These genes encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. ARF3 functions as an allosteric activator of the cholera toxin subunit, an ADP-ribosyltrans...

重组蛋白

ART1 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPY-04209

Species: Cynomolgus

Expression System: HEK293 Cells

PARP2 Protein, Human, Recombinant (GST & His)

Cat.No: TMPH-01881

Species: Human

Expression System: Baculovirus Insect Cells

ART3 Protein, Human, Recombinant (His)

Cat.No: TMPY-03386

Species: Human

Expression System: HEK293 Cells

PARP2 Protein, Human, Recombinant (His)

Cat.No: TMPH-01880

Species: Human

Expression System: E. coli

ART4/CD297 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPY-03777

Species: Cynomolgus

Expression System: HEK293 Cells

ART4/CD297 Protein, Rat, Recombinant (His)

Cat.No: TMPY-03312

Species: Rat

Expression System: HEK293 Cells

ART4/CD297 Protein, Cynomolgus, Recombinant (hFc)

Cat.No: TMPY-03544

Species: Cynomolgus

Expression System: HEK293 Cells

TIPARP Protein, Human, Recombinant (His)

Cat.No: TMPH-01945

Species: Human

Expression System: Baculovirus Insect Cells

PARP11 Protein, Human, Recombinant (His)

Cat.No: TMPH-01879

Species: Human

Expression System: E. coli

PARP9 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01944

Species: Human

Expression System: HEK293 Cells

PARP14 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01942

Species: Human

Expression System: HEK293 Cells

PARP9 Protein, Human, Recombinant (His)

Cat.No: TMPH-01882

Species: Human

Expression System: E. coli

PARP4 Protein, Human, Recombinant (His)

Cat.No: TMPH-01943

Species: Human

Expression System: E. coli

ART4/CD297 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-02822

Species: Mouse

Expression System: HEK293 Cells

Diphtheria toxin Protein, Corynephage omega, Recombinant (His & Myc)

Cat.No: TMPH-00432

Species: Corynephage omega

Expression System: E. coli

PARP12 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01941

Species: Human

Expression System: E. coli

ART1 Protein, Human, Recombinant (His)

Cat.No: TMPY-06532

Species: Human

Expression System: HEK293 Cells

Exotoxin A Protein, Pseudomonas aeruginosa, Recombinant (His & KSI)

Cat.No: TMPH-03168

Species: Pseudomonas aeruginosa

Expression System: E. coli

ART4/CD297 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-02738

Species: Mouse

Expression System: HEK293 Cells

CARDS Protein, Mycoplasma pneumoniae, Recombinant (His & Myc)

Cat.No: TMPH-03026

Species: Mycoplasma pneumoniae

Expression System: E. coli

PTX S1 Protein, Bordetella pertussis, Recombinant (His)

Cat.No: TMPH-00207

Species: Bordetella pertussis

Expression System: P. pastoris (Yeast)

SIRT6 Protein, Human, Recombinant (GST)

Cat.No: TMPH-01742

Species: Human

Expression System: E. coli

ARF5 Protein, Human, Recombinant (His)

Cat.No: TMPY-03868

Species: Human

Expression System: E. coli

ARF3 Protein, Human, Recombinant (His)

Cat.No: TMPY-03796

Species: Human

Expression System: E. coli

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