首页工具

登录

搜索结果

Search Results for " acl "

Targets Recommended: HCV Protease

70

抑制剂 & 化合物

17

天然产物

5

重组蛋白

2

同位素标记化合物

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name	Target	Signaling Pathways
T6229	Daclatasvir Daklinza,达卡他韦,EBP 883,达拉他韦,BMS-790052	HCV Protease	Microbiology/Virology; Proteases/Proteasome
	Daclatasvir (EBP 883) 是一种高度选择性的 HCV NS5A 抑制剂，EC50 为 9-50 pM，适用于细胞培养中的多种 HCV 复制子基因型和 JFH-1 基因型 2a 感染性病毒。
T9694	Emraclidine CVL-231	AChR	Neuroscience
	Emraclidine (CVL-231) 是一种毒蕈碱 M4 受体阳性变构调节剂，可用于神经系统疾病研究。
T4440	Saclofen	GABA Receptor	Membrane transporter/Ion channel; Neuroscience
	Saclofen 是竞争性GABAB 受体拮抗剂(IC50:7.8 μM)。它可研究 GABAB 受体调节大脑中缓慢抑制性突触后电位的功能。
T6355	(R)-baclofen STX209,Arbaclofen,(R)-巴氯芬	GABA Receptor	Membrane transporter/Ion channel; Neuroscience
	(R)-baclofen (STX209) 是一种选择性GABAB 受体激动剂。
T1065	Baclofen 巴氯芬,Lioresal	GABA Receptor	Membrane transporter/Ion channel; Neuroscience
	Baclofen (Lioresal) 是 γ-氨基丁酸 (GABA) 的亲脂性衍生物，是可口服的选择性代谢型 GABA-B 受体激动剂，具有高血脑屏障渗透率，用于治疗因脊髓损伤和多发性硬化引起的痉挛。
T8604	Fenaclon Fenaclonum	Others	Others
	Fenaclon (Fenaclonum) 是一种抗惊厥药。它适用于治疗癫痫。
T21371	Apraclonidine hydrochloride Iopidine,ALO 2145,Apraclonidina,P-aminoclonidine,4-Aminoclonidine,Apraclonidine HCl,Apraclonidinum	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Apraclonidine hydrochloride (ALO 2145) 是一种 α2-肾上腺素能激动剂和弱的 α-1 肾上腺素能受体激动剂。 Apaclonidine hydrochloride 可降低人眼的眼内压，可用于青光眼治疗的研究。
T28303	Pazinaclone A-77000,DN-2327,DN2327,DN 2327,A 77000,A77000	GABA Receptor	Membrane transporter/Ion channel; Neuroscience
	Pazinaclone 是一种非苯二氮卓类（GABAA）部分激动剂，具有镇静和抗焦虑活性。
T38273	Paclobutrazol (2R,3R)-Paclobutrazol,多效唑,(R,R)-paclobutrazol,2R,3R-Paclobutrazol	Antifungal	Microbiology/Virology
	Paclobutrazol ((R,R)-paclobutrazol) 是一种含有三唑的植物生长延缓剂，能抑制赤霉素的生物合成。Paclobutrazol 还具有抗真菌 (antifungal) 活性。Paclobutrazol 能抑制脱落酸的合成，诱导植物的耐冷性植物。Paclobutrazol 通常用于赤霉素在植物生物学中作用的研究。
T19533	Pyraclonil	Others	Others
	Pyraclonil 作为一种除草剂，有效地控制了敏感型(S)和多重抗药性(MHR)E. indica群体。Pyraclonil 作为丙啶类光敏色素原氧化酶(PPO)抑制剂发挥作用。
T38272	Thiacloprid	AChR; Parasite	Microbiology/Virology; Neuroscience
	Thiacloprid 属于氯烟碱类杀虫剂，主要用于防治蔬菜和果园中的蚜虫。它会破坏 DNA 的稳定性，通过疏水或氢相互作用，结合到小沟槽中，改变 DNA 的结构和稳定性。
T12367	Parsaclisib INCB050465	PI3K	PI3K/Akt/mTOR signaling
	Parsaclisib (INCB050465) 是有效的、选择性的、具有口服活性的PI3Kδ抑制剂，其 IC50=1 nM。它相对于其他 PI3K I 类同工型的选择性约为 20000 倍。它可用于复发或难治性 B 细胞恶性肿瘤的研究。
T23147	Phaclofen 3-Amino-2-(4-chlorophenyl)propanephosphonic acid	GABA Receptor	Membrane transporter/Ion channel; Neuroscience
	Phaclofen (3-Amino-2-(4-chlorophenyl)propanephosphonic acid) 是一种选择性 GABAB receptor 拮抗剂，可部分拮抗（-）-巴氯芬的镇静作用，可逆地拮抗巴氯芬或GABA对豚鼠回肠和远端结肠胆碱能抽搐反应的抑制，可用于研究神进系统疾病。
T73689	Daclizumab Ro 24-7375,Zenapax	IL Receptor	Immunology/Inflammation
	Daclizumab （Zenapax）为人源化单抗，能特异性地抑制IL-2R-HA的α亚单位。Daclizumab （Zenapax）能通过与CD25的特异性结合而抑制IL-2和IL-2R-HA的结合。Daclizumab （Zenapax）研究多发性硬化症。
T1495	Cefaclor monohydrate Cefaclor,头孢克洛一水物,头孢克洛一水合物,Cefaclorum,Cefachlor	Antibacterial; Antibiotic	Microbiology/Virology
	Cefaclor monohydrate (Cefaclorum) 是一种抗生素，可特异性地结合青霉素结合蛋白。
T9491	Pyraclostrobin	Antibacterial; Antifungal	Microbiology/Virology
	Pyraclostrobin 是一种球果苷杀菌剂，可诱导 3T3-L1 细胞内甘油三酯的积累，还可抑制真菌和哺乳动物细胞的线粒体复合物 III 。
T8630	Baclofen hydrochloride 4-amino-3-(4-chlorophenyl)butanoic acid hydron chloride	GABA Receptor	Membrane transporter/Ion channel; Neuroscience
	Baclofen hydrochloride (4-amino-3-(4-chlorophenyl)butanoic acid hydron chloride) 是一种 GAMMA-AMINOBUTYRIC ACID 衍生物，是一种特异性 GABA-B 受体激动剂。它用于治疗肌肉痉挛，尤其是由于脊髓损伤引起的肌肉痉挛。其治疗效果来自于脊髓和脊髓上部位的作用，通常是减少兴奋性传递。
T83653	SACLAC	Apoptosis; Caspase	Apoptosis; Proteases/Proteasome
	SACLAC 是一种半胱天冬酶活化抑制剂，具有抗肿瘤活性，可降低AML细胞活力，抑制AML细胞增殖，增加AML细胞死亡，并诱导AML细胞凋亡，可用于研究急性髓系白血病和癌症。
T6969	Imidacloprid	Others	Others
	Imidacloprid 是一种新烟碱类农药，广泛用于控制蔬菜，谷物，茶叶和棉花的害虫。
T7121	Sulfaclozine 磺胺氯吡嗪,Sulfachloropyrazine,Sulfachloropyrazine sodium,N-(5-氯-3-吡嗪基)-4-氨基苯磺酰胺	Antibacterial; Antibiotic; Parasite	Microbiology/Virology
	Sulfachloropyrazine sodium(Sulfachloropyrazine) 是一种磺酰胺衍生物，具有抗菌和抗球虫作用。Sulfachloropyrazine sodium(Sulfachloropyrazine) 用于各种家禽疾病。
T2555	Aclidinium bromide LAS 34273,LAS-W 330,阿地溴铵	AChR	Neuroscience
	Aclidinium bromide (LAS-W 330) 是长效可吸入型的毒蕈碱拮抗剂，有用于慢性阻塞性肺病 (COPD) 的研究潜力。
T11852	Linaclotide	Guanylate cyclase	GPCR/G Protein
	Linaclotide 是一种有效的选择性鸟苷酸环化酶 C 激动剂，可用于治疗便秘型肠易激综合征 (IBS-C) 和慢性便秘的研究。
T72077	Imidacloprid-urea	Others	Others
	Imidacloprid-urea 是吡虫啉的次级代谢产物。吡虫啉是一种有效且广泛使用的新烟碱类化合物，对谷物，蔬菜，茶叶和棉花的害虫具有抑制作用。Imidacloprid-urea 可以占据或阻断吡虫啉在土壤上的吸附位点，从而可能影响吡虫啉在环境中的去向、转运和生物利用度。
T1786	Daclatasvir dihydrochloride BMS-790052 dihydrochloride,盐酸达拉他韦	HCV Protease	Microbiology/Virology; Proteases/Proteasome
	Daclatasvir dihydrochloride (BMS-790052 dihydrochloride) 是有机阴离子转运多肽 1B(OATP1B) 和 OATP1B3抑制剂，IC50分别为 1.5 µM 和 3.27 µM。它也具有口服活性的 HCV NS5A 蛋白抑制剂，多种 HCV 复制子基因型的 EC50范围为 9-146 pM。
T7635	Raclopride	Dopamine Receptor	GPCR/G Protein; Neuroscience
	Raclopride 是多巴胺D2/D3受体拮抗剂，具有抗精神活性，能够结合D2(Ki:1.8 nM)和D3(Ki:3.5 nM)受体。
T20864	7-Troc-paclitaxel	Others	Others
	7-Troc-paclitaxel 是紫杉醇的前体，紫杉醇具有抗肿瘤活性。
T6436	Cefaclor Panoral,Kefral,Cefaclorum,头孢克洛	Others; Antibacterial; Antibiotic	Microbiology/Virology; Others
	Cefaclor (Panoral) 是一种可特异性结合青霉素结合蛋白的抗生素。
TP2403	Recanaclotide IW 9179,IW-9179,IW9179
	Recanaclotide can be used to treat Gastroparesis, Functional Dyspepsia, and Other Gastrointestinal Disorders.
T26554	Aclerastide DSC-127,DSC 127,NorLeu-3-A(1-7),DSC127,NorLeu-3A(1-7)
	Aclerastide is an angiotensin receptor agonist. Administration of Aclerastide reduced fibrosis and scarring in the healing wounds. This action was more pronounced with longer administration of the peptide after injury. The action of this peptide was block
T17306	(R)-Baclofen hydrochloride Arbaclofen hydrochloride,(R)-巴氯芬盐酸盐	GABA Receptor	Membrane transporter/Ion channel; Neuroscience
	Arbaclofen hydrochloride, a Gamma-Aminobutyric Acid derivative, is a specific agonist of GABA-B receptors, it is used to treat spasticity, especially that due to spinal cord damage. It acts at spinal and supraspinal sites, generally reduces excitatory tra
T124517	Fumigaclavine C	Others	Others
	Fumigaclavine C 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T124517，CAS号为 62867-47-4。
T23842	Butaclamol free base Butaclamol,AY 23028,AY 23,028,AY-23028,AY23,028,AY-23,028	Others	Others
	Butaclamol is a typical antipsychotic which was never marketed. It also acts as a dopamine receptor antagonist.
T28289	Paclitaxel-SMCC SMCC taxol, Taxol-SMCC, Taxol SMCC,Paclitaxel with SMCC linker,SMCC-Taxol,Paclitaxel ADC conjugate.	Others	Others
	Paclitaxel-SMCC is a paclitaxel derivative with a SMCC linker. (Succinimidyl-4-( N -maleimidomethyl)cyclohexane-1-carboxylate). Paclitaxel-SMCC can be used to synthesize Paclitaxel bioconjugates with enzymes, antobodies, antigens and other biopolymers. Pa
T125178	Isosaxalin; Heraclenol	Others	Others
	Isosaxalin; Heraclenol 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T125178，CAS号为 26091-76-9。
T68219	Peraclopone	Others	Others
	Peraclopone is a hypolidemic drug. It is an inhibitor of 7-Dehydrocholesterol reductase. Peraclopone potently inhibits the final step in cholesterol biosynthesis. Feeding this agent to rats leads to a rapid replacement of membrane cholesterol with its immediate precursor 7-dehydrocholesterol, and a dramatic reduction in plasma sterol concentration. Peraclopone caused a dose-dependent decrease in cholesterol and a concomitant accumulation of provitamin D3 (7-dehydrocholesterol) in the skin, which...
T26553	Aclatonium Napadisilate Acaltonium napadisilate	Others	Others
	Aclatonium Napadisilate, a cholinergic agonist, has been shown to stimulates endocrine and exocrine pancreatic secretion.
T23618	Aclantate Aclantato,Aclantatum,Hoe473,Hoe 473	Others	Others
	Aclantate is a nonsteroidal anti-inflammatory drug.
T36398	Paclitaxel octadecanedioate	Others	Others
	Paclitaxel octadecanedioate is a prodrug form of paclitaxel that is comprised of paclitaxel conjugated to 1,18-octadecanedioic acid.1 Unlike paclitaxel, it does not promote tubulin polymerization in vitro when used at a concentration of 10 μM. A 5:1 mixture of paclitaxel octadecanedioate:human serum albumin (HSA) is cytotoxic to HT-1080, PANC-1, and HT-29 cells (IC50s = 12, 2.48, and 8.62 nM, respectively). This mixture reduces tumor growth and increases survival in an HT-1080 mouse xenograft mo...
T17357	AcLys-PABC-VC-Aur0101	Others; Drug-Linker Conjugates for ADC	Antibody-drug Conjugate/ADC Related; Others
	AcLys-PABC-VC-Aur0101 is a drug-linker conjugate for anti-CXCR4 ADC with potent antitumor activity, comprising the auristatin microtubule inhibitor Aur0101, connected through the cleavable linker AcLys-PABC-VC[1].
T13071	Talsaclidine	Others	Others
	Talsaclidine is an agonist of muscarinic with preferential neuron-stimulating properties. Talsaclidine is a full agonist at the M1 subtype, and as a partial agonist at the M2 and M3 subtypes.
T22495	2-Hydroxysaclofen	Others	Others
	2-Hydroxysaclofen is a GABAB receptor antagonist.
T34769	Taclamine hydrochloride AY-22,214,AY 22214	Others	Others
	Taclamine hydrochloride is a biochemical with minor sedative properties.
T60238	Acloproxalap	Others	Others
	Acloproxalap 是一种基于喹啉的醛清除剂，可用于研究有毒醛积累的疾病，如眼部、皮肤等炎症性疾病，肺炎等呼吸系统疾病，器官疾病以及病毒感染相关性综合症等。
T69355	Butaclamol HCl	Others	Others
	Butaclamol, also known as AY-23,028, is a typical antipsychotic which was never marketed. Sold as the hydrochloride salt for use in research, the compound acts as a dopamine receptor antagonist.
T74007	Daclatasvir Impurity C	Others	Others
	Daclatasvir Impurity C 是 Daclatasvir 的一种杂质。Daclatasvir 是一种有效的 HCVNS5A 蛋白抑制剂。
T20265	Paclitaxel Poliglumex CT2103,Opaxio,PG-TXL,CT-2103,PPX,CT 2103	Others	Others
	Paclitaxel Poliglumex is cyclohexane isolated from the bark of the Pacific yew tree.
T33862	Paclitaxel-Succinic acid Paclitaxel-hemisuccinic acid	Others	Others
	Paclitaxel-Succinic acid (paclitaxel-succinate , paclitaxel-semisucinic acid)is a paclitaxel derivative with a succinic acid linker. Paclitaxel-Succinic acid can be used to prepare paclitaxel conjugates for drug delivery and nanomedicine research.
T29611	Acluracil	Others	Others
	Acluracil is a biochemical.
T28297	Parsaclisib hydrochloride Parsaclisib HCl,INCB-50465,INCB 050465,INCB-050465,INCB050465 HCl,INCB 50465,INCB50465 HCl	PI3K	PI3K/Akt/mTOR signaling
	Parsaclisib hydrochloride (INCB050465 HCl) 是一种选择性的、有效的，具有口服活性的 PI3Kδ抑制剂，IC50=1 nM。它相对于其他 PI3K I 类同工型的选择性约为 20000 倍。它可用于复发或难治性 B 细胞恶性肿瘤的研究。
T74006	Daclatasvir Impurity B	Others	Others
	Daclatasvir Impurity B为Daclatasvir杂质之一，后者为一种高效的HCV NS5A蛋白抑制剂。

化合物

Cat.No: T6229

Synonym: Daklinza,达卡他韦,EBP 883,达拉他韦,BMS-790052

Target: HCV Protease

Cat.No: T9694

Synonym: CVL-231

Target: AChR

Cat.No: T4440

Target: GABA Receptor

Cat.No: T6355

Synonym: STX209,Arbaclofen,(R)-巴氯芬

Target: GABA Receptor

Cat.No: T1065

Synonym: 巴氯芬,Lioresal

Target: GABA Receptor

Cat.No: T8604

Synonym: Fenaclonum

Target: Others

Apraclonidine hydrochloride

Cat.No: T21371

Synonym: Iopidine,ALO 2145,Apraclonidina,P-aminoclonidine,4-Aminoclonidine,Apraclonidine HCl,Apraclonidinum

Target: Adrenergic Receptor

Cat.No: T28303

Synonym: A-77000,DN-2327,DN2327,DN 2327,A 77000,A77000

Target: GABA Receptor

Cat.No: T38273

Synonym: (2R,3R)-Paclobutrazol,多效唑,(R,R)-paclobutrazol,2R,3R-Paclobutrazol

Target: Antifungal

Cat.No: T19533

Target: Others

Cat.No: T38272

Target: AChR, Parasite

Cat.No: T12367

Synonym: INCB050465

Target: PI3K

Cat.No: T23147

Synonym: 3-Amino-2-(4-chlorophenyl)propanephosphonic acid

Target: GABA Receptor

Cat.No: T73689

Synonym: Ro 24-7375,Zenapax

Target: IL Receptor

Cefaclor monohydrate

Cat.No: T1495

Synonym: Cefaclor,头孢克洛一水物,头孢克洛一水合物,Cefaclorum,Cefachlor

Target: Antibacterial, Antibiotic

Cat.No: T9491

Target: Antibacterial, Antifungal

Baclofen hydrochloride

Cat.No: T8630

Synonym: 4-amino-3-(4-chlorophenyl)butanoic acid hydron chloride

Target: GABA Receptor

Cat.No: T83653

Target: Apoptosis, Caspase

Cat.No: T6969

Target: Others

Cat.No: T7121

Synonym: 磺胺氯吡嗪,Sulfachloropyrazine,Sulfachloropyrazine sodium,N-(5-氯-3-吡嗪基)-4-氨基苯磺酰胺

Target: Antibacterial, Antibiotic, Parasite

Aclidinium bromide

Cat.No: T2555

Synonym: LAS 34273,LAS-W 330,阿地溴铵

Target: AChR

Cat.No: T11852

Target: Guanylate cyclase

Imidacloprid-urea

Cat.No: T72077

Target: Others

Daclatasvir dihydrochloride

Cat.No: T1786

Synonym: BMS-790052 dihydrochloride,盐酸达拉他韦

Target: HCV Protease

Cat.No: T7635

Target: Dopamine Receptor

7-Troc-paclitaxel

Cat.No: T20864

Target: Others

Cat.No: T6436

Synonym: Panoral,Kefral,Cefaclorum,头孢克洛

Target: Others, Antibacterial, Antibiotic

Cat.No: TP2403

Synonym: IW 9179,IW-9179,IW9179

Cat.No: T26554

Synonym: DSC-127,DSC 127,NorLeu-3-A(1-7),DSC127,NorLeu-3A(1-7)

(R)-Baclofen hydrochloride

Cat.No: T17306

Synonym: Arbaclofen hydrochloride,(R)-巴氯芬盐酸盐

Target: GABA Receptor

Fumigaclavine C

Cat.No: T124517

Target: Others

Butaclamol free base

Cat.No: T23842

Synonym: Butaclamol,AY 23028,AY 23,028,AY-23028,AY23,028,AY-23,028

Target: Others

Paclitaxel-SMCC

Cat.No: T28289

Synonym: SMCC taxol, Taxol-SMCC, Taxol SMCC,Paclitaxel with SMCC linker,SMCC-Taxol,Paclitaxel ADC conjugate.

Target: Others

Isosaxalin; Heraclenol

Cat.No: T125178

Target: Others

Cat.No: T68219

Target: Others

Aclatonium Napadisilate

Cat.No: T26553

Synonym: Acaltonium napadisilate

Target: Others

Cat.No: T23618

Synonym: Aclantato,Aclantatum,Hoe473,Hoe 473

Target: Others

Paclitaxel octadecanedioate

Cat.No: T36398

Target: Others

AcLys-PABC-VC-Aur0101

Cat.No: T17357

Target: Others, Drug-Linker Conjugates for ADC

Cat.No: T13071

Target: Others

2-Hydroxysaclofen

Cat.No: T22495

Target: Others

Taclamine hydrochloride

Cat.No: T34769

Synonym: AY-22,214,AY 22214

Target: Others

Cat.No: T60238

Target: Others

Cat.No: T69355

Target: Others

Daclatasvir Impurity C

Cat.No: T74007

Target: Others

Paclitaxel Poliglumex

Cat.No: T20265

Synonym: CT2103,Opaxio,PG-TXL,CT-2103,PPX,CT 2103

Target: Others

Paclitaxel-Succinic acid

Cat.No: T33862

Synonym: Paclitaxel-hemisuccinic acid

Target: Others

Cat.No: T29611

Target: Others

Parsaclisib hydrochloride

Cat.No: T28297

Synonym: Parsaclisib HCl,INCB-50465,INCB 050465,INCB-050465,INCB050465 HCl,INCB 50465,INCB50465 HCl

Target: PI3K

Daclatasvir Impurity B

Cat.No: T74006

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T20578	Maclurin Fustic extract,Morintannic acid,NSC 83240	Free radical scavengers; Reactive Oxygen Species	Immunology/Inflammation; Metabolism; NF-κB; oxidation-reduction
	Maclurin (NSC-83240) 是桑枝的酚类成分，具有抗转移作用。 Maclurin 可有效防止 OH 诱导的 DNA 和 MSCs 损伤，可用于预防多种疾病或 MSCs 移植的研究。
T5749	10-Deacetyl-7-xylosyl paclitaxel 10-Deacetyl-7-xylosyltaxol,10-Deacetyltaxol 7-Xyloside,7-Xylosyl-10-deacetyltaxol,7-木糖甙-10-脱乙酰基紫杉醇,10-Deacetylpaclitaxel 7-Xyloside	Others; Microtubule Associated; ADC Cytotoxin	Antibody-drug Conjugate/ADC Related; Cytoskeletal Signaling; Others
	10-Deacetyl-7-xylosyl paclitaxel (7-Xylosyl-10-deacetyltaxol) 是一种紫杉醇衍生物，具有改进的药理特性和更高的水溶性，用于治疗癌症。
T0968	Paclitaxel Taxol,紫杉醇,NSC 125973	Apoptosis; Microtubule Associated; Autophagy; ADC Cytotoxin	Antibody-drug Conjugate/ADC Related; Apoptosis; Autophagy; Cytoskeletal Signaling
	Paclitaxel (Taxol) 属于天然产物，是一种微管聚合物稳定剂。Paclitaxel 具有抗肿瘤活性；通过诱导有丝分裂停滞、细胞凋亡、细胞自噬等，导致细胞死亡。
TL0013	Heraclenin 独活内酯	Anti-infection; Immunology/Inflammation related	Immunology/Inflammation; Microbiology/Virology
	Heraclenin 是一种天然呋喃香豆素。它浓度依赖性的靶向激活的 T 细胞核因子 (NFAT) ，抑制人原代 T 细胞中 T 细胞受体介导的增殖。
T21502	Aclacinomycin A Aclarubicin	Topoisomerase	DNA Damage/DNA Repair
	Aclacinomycin A (Aclarubicin) 是一种从加利莱链霉菌中分离出的新型蒽环类抗生素，具有抗肿瘤活性。Aclacinomycin A 是拓扑异构酶 I 和 II 的抑制剂，抑制 RNA 活性。Aclacinomycin A 可用于研究复发性白血病和晚期恶性淋巴瘤。
TN1730	Heraclenol	Antibacterial	Microbiology/Virology
	Heraclenol 来自当归的果实，具有抗菌活性。 Heraclenol 可作为欧芹和莴苣种子中的发芽抑制剂。
T5738	7-Epi 10-desacetyl paclitaxel 10-Deacetyl-7-epipaclitaxel,7-Epi-10-deacetyltaxol,7-表-10-去乙酰基云南紫杉宁A	Others; ADC Cytotoxin	Antibody-drug Conjugate/ADC Related; Others
	7-Epi 10-desacetyl paclitaxel (10-Deacetyl-7-epipaclitaxel) 是紫杉醇衍生物，对 HeLa 细胞具有细胞毒性(IC50:85 μM)。
TN5912	Macluraxanthone 3-Hydroxyblancoxanthone	Antioxidant; TNF	Apoptosis; oxidation-reduction
	Macluraxanthone (3-Hydroxyblancoxanthone) 具有许多生物活性，包括抗胆碱酯酶、抗氧化、抗癌、抗疟疾、抗炎和免疫调节作用。Macluraxanthone 通过增加表达CD86的巨噬细胞的百分比，同时减少其CD14、CD11b 和CD80的表达，来促进M1类促炎症巨噬细胞的极化。Macluraxanthone 在促炎症刺激物脂多糖的存在下明显减少了TNF-α和IL-10细胞因子的产生。
TN4202	(-)-Heraclenol	Antifection	Microbiology/Virology
	(-)-Heraclenol shows in vitro anti-plasmodial activity against chloroquine-sensitive and chloroquine-resistant strains of Plasmodium falciparum.(-)-Heraclenol has moderate antibacterial and antifungal activities.
TN4203	Heraclenol 3'-O-[beta-D-apiofuranosyl-(1-6)-beta-D-glucopyranoside]	Others	Others
	Heraclenol 3'-O-[beta-D-apiofuranosyl-(1-6)-beta-D-glucopyranoside] 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN4203，CAS号为 765316-44-7。
TN4205	Heraclenol acetonide	Others	Others
	Heraclenol acetonide 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN4205，CAS号为 64790-68-7。
TN4204	Heraclenol 3'-O-beta-D-glucopyranoside	Others	Others
	Heraclenol 3'-O-beta-D-glucopyranoside 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN4204，CAS号为 32207-10-6。
T10238	Aclacinomycin A hydrochloride 盐酸阿柔比星,Aclarubicin hydrochloride	Proteasome	Proteases/Proteasome; Ubiquitination
	Aclacinomycin A (Aclarubicin) hydrochloride is a fluorescent molecule and the first described non-peptidic inhibitor showing discrete specificity for the CTRL (chymotrypsin-like) activity of the 20S proteasome. Aclacinomycin A hydrochloride is also a dual inhibitor of topoisomerase I and II.
T73913	Fumigaclavine A	Others	Others
	Fumigaclavine A 是一种棒麦角素型生物碱，是由烟曲霉 (Aspergillus fumigatus) 产生的真菌毒素。可以从污染发霉的青贮饲料中分离出 A. fumigatus。
T80015	(±)-Heraclenol	Others	Others
	(±)-Heraclenol，香豆素类化合物，从当归(Angelica)果实中提取，表现出抗菌特性。
T79935	Forrestiacids J	ATP Citrate Lyase	Metabolism
	Forrestiacids J为一种特异性抑制ATP-柠檬酸裂解酶 (ACL) 的化合物，其IC50值为2.6 μM。
T79936	Forrestiacids K	ATP Citrate Lyase	Metabolism
	Forrestiacids K, 萜类化合物，源自Pseudotsuga forrestii，作为ATP-citrate lyase (ACL) 的抑制剂。

天然产物

Cat.No: T20578

Synonym: Fustic extract,Morintannic acid,NSC 83240

Target: Free radical scavengers, Reactive Oxygen Species

10-Deacetyl-7-xylosyl paclitaxel

Cat.No: T5749

Synonym: 10-Deacetyl-7-xylosyltaxol,10-Deacetyltaxol 7-Xyloside,7-Xylosyl-10-deacetyltaxol,7-木糖甙-10-脱乙酰基紫杉醇,10-Deacetylpaclitaxel 7-Xyloside

Target: Others, Microtubule Associated, ADC Cytotoxin

Cat.No: T0968

Synonym: Taxol,紫杉醇,NSC 125973

Target: Apoptosis, Microtubule Associated, Autophagy, ADC Cytotoxin

Cat.No: TL0013

Synonym: 独活内酯

Target: Anti-infection, Immunology/Inflammation related

Aclacinomycin A

Cat.No: T21502

Synonym: Aclarubicin

Target: Topoisomerase

Cat.No: TN1730

Target: Antibacterial

7-Epi 10-desacetyl paclitaxel

Cat.No: T5738

Synonym: 10-Deacetyl-7-epipaclitaxel,7-Epi-10-deacetyltaxol,7-表-10-去乙酰基云南紫杉宁A

Target: Others, ADC Cytotoxin

Macluraxanthone

Cat.No: TN5912

Synonym: 3-Hydroxyblancoxanthone

Target: Antioxidant, TNF

Cat.No: TN4202

Target: Antifection

Heraclenol 3'-O-[beta-D-apiofuranosyl-(1-6)-beta-D-glucopyranoside]

Cat.No: TN4203

Target: Others

Heraclenol acetonide

Cat.No: TN4205

Target: Others

Heraclenol 3'-O-beta-D-glucopyranoside

Cat.No: TN4204

Target: Others

Aclacinomycin A hydrochloride

Cat.No: T10238

Synonym: 盐酸阿柔比星,Aclarubicin hydrochloride

Target: Proteasome

Fumigaclavine A

Cat.No: T73913

Target: Others

(±)-Heraclenol

Cat.No: T80015

Target: Others

Forrestiacids J

Cat.No: T79935

Target: ATP Citrate Lyase

Forrestiacids K

Cat.No: T79936

Target: ATP Citrate Lyase

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-02483	ATP citrate lyase/ACLY Protein, Human, Recombinant (His) ATPCL,ACL,ATP citrate lyase,CLATP	Human	Baculovirus Insect Cells
	ATP citrate lyase, also known as Acly or Acl, is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is composed of two polymer chains which are polypeptides in human. ATP citrate lyase is responsible for catalyzing the conversion of citrate and CoA into acetyl-CoA and oxaloacetate, along with the hydrolysis of ATP. A definitive role for ATP citrate lyase in tumorigenesis has emerged from ATP citrate lyase RNAi and chemical inhibitor studies, show...
TMPH-00322	Snaclec rhodocytin subunit beta Protein, Calloselasma rhodostoma, Recombinant (His) Snaclec rhodocytin subunit beta,Aggretin beta chain...	Calloselasma rhodostoma	P. pastoris (Yeast)
	Elicits platelet aggregation by the binding to the C-type lectin domain family 1 member B (CLEC1B/CLEC2). Binding leads to tyrosine phosphorylation in the cytoplasmic tail of CLEC1B, which promotes the binding of spleen tyrosine kinase (Syk), subsequent activation of PLCgamma2, and platelet activation and aggregation. Binding to GPIbalpha (GP1BA) and alpha2/beta-1 (ITGA2/ITGB1) may also induce aggregation, but this is controversial. Snaclec rhodocytin subunit beta Protein, Calloselasma rhodostom...
TMPH-00321	Snaclec rhodocytin subunit alpha Protein, Calloselasma rhodostoma, Recombinant (His & SUMO) Rhodoaggretin subunit alpha,Aggretin alpha chain,Snacl	Calloselasma rhodostoma	E. coli
	Elicits platelet aggregation by the binding to the C-type lectin domain family 1 member B (CLEC1B/CLEC2). Binding leads to tyrosine phosphorylation in the cytoplasmic tail of CLEC1B, which promotes the binding of spleen tyrosine kinase (Syk), subsequent activation of PLC-gamma-2, and platelet activation and aggregation. Binding to GPIbalpha (GP1BA) and alpha-2/beta-1 (ITGA2/ITGB1) may also induce aggregation, but this is controversial. Snaclec rhodocytin subunit alpha Protein, Calloselasma rhodo...
TMPH-00323	Snaclec rhodocytin subunit beta Protein, Calloselasma rhodostoma, Recombinant (His & Myc) Aggretin beta chain,Rhodoaggretin subunit beta,Snacl	Calloselasma rhodostoma	E. coli
	Elicits platelet aggregation by the binding to the C-type lectin domain family 1 member B (CLEC1B/CLEC2). Binding leads to tyrosine phosphorylation in the cytoplasmic tail of CLEC1B, which promotes the binding of spleen tyrosine kinase (Syk), subsequent activation of PLCgamma2, and platelet activation and aggregation. Binding to GPIbalpha (GP1BA) and alpha2/beta-1 (ITGA2/ITGB1) may also induce aggregation, but this is controversial. Snaclec rhodocytin subunit beta Protein, Calloselasma rhodostom...
TMPH-00320	Snaclec rhodocytin subunit alpha Protein, Calloselasma rhodostoma, Recombinant (His) Rhodoaggretin subunit alpha,Aggretin alpha chain,Snacl	Calloselasma rhodostoma	P. pastoris (Yeast)
	Elicits platelet aggregation by the binding to the C-type lectin domain family 1 member B (CLEC1B/CLEC2). Binding leads to tyrosine phosphorylation in the cytoplasmic tail of CLEC1B, which promotes the binding of spleen tyrosine kinase (Syk), subsequent activation of PLC-gamma-2, and platelet activation and aggregation. Binding to GPIbalpha (GP1BA) and alpha-2/beta-1 (ITGA2/ITGB1) may also induce aggregation, but this is controversial. Snaclec rhodocytin subunit alpha Protein, Calloselasma rhodo...

重组蛋白

ATP citrate lyase/ACLY Protein, Human, Recombinant (His)

Cat.No: TMPY-02483

Species: Human

Expression System: Baculovirus Insect Cells

Snaclec rhodocytin subunit beta Protein, Calloselasma rhodostoma, Recombinant (His)

Cat.No: TMPH-00322

Species: Calloselasma rhodostoma

Expression System: P. pastoris (Yeast)

Snaclec rhodocytin subunit alpha Protein, Calloselasma rhodostoma, Recombinant (His & SUMO)

Cat.No: TMPH-00321

Species: Calloselasma rhodostoma

Expression System: E. coli

Snaclec rhodocytin subunit beta Protein, Calloselasma rhodostoma, Recombinant (His & Myc)

Cat.No: TMPH-00323

Species: Calloselasma rhodostoma

Expression System: E. coli

Snaclec rhodocytin subunit alpha Protein, Calloselasma rhodostoma, Recombinant (His)

Cat.No: TMPH-00320

Species: Calloselasma rhodostoma

Expression System: P. pastoris (Yeast)

Cat. No.	Product Name	Target	Signaling Pathways
TMID-0018	Paclitaxel-d5	ADC Cytotoxin	Antibody-drug Conjugate/ADC Related
	Paclitaxel-d5 是 Paclitaxel 的氘代化合物。Paclitaxel 的 CAS 号为 33069-62-4。Paclitaxel 是一种从太平洋紫杉树皮中分离出来的环癸烷。它以聚合形式稳定微管，导致细胞死亡。
TMIJ-0314	Baclofen-d4
	Baclofen-d4 是 Baclofen 的氘代化合物。Baclofen 的 CAS 号为 1134-47-0。Baclofen 是 γ-氨基丁酸 (GABA) 的亲脂性衍生物，是可口服的选择性代谢型 GABA-B 受体激动剂，具有高血脑屏障渗透率，用于治疗因脊髓损伤和多发性硬化引起的痉挛。

同位素标记化合物

Cat.No: TMID-0018

Target: ADC Cytotoxin

Cat.No: TMIJ-0314

我们的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved. 沪ICP备20019793号-4

沪公网安备 31010602006700号

沪公网安备 31010602006700号

TargetMol Loading

联系我们

电话：

400-820-0310

邮箱：

service@tsbiochem.com

QQ：

2881945090（终端用户）

2885109491（经销商）

经销：

终端：

地址：

上海市静安区江场三路238号8楼