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Search Results for " acc1 "

Targets Recommended: Others

13

抑制剂 & 化合物

5

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T61978	ACC1/2-IN-2	Others	Others
	ACC1/2-IN-2 (compound PF-3) 是有效的 ACC1/2抑制剂，IC50分别为 22 和 48 nM。 ACC1/2-IN-2 显示出抗增殖活性，可用于癌症相关研究。
T63961	ACC1/2-IN-1	Others	Others
	ACC1/2-IN-1 是 ACC1/2 的有效抑制剂，可作用于 ACC1 (IC50: 98.06 nM) 和 ACC2 (IC50: 29.43 nM)。ACC1/2-IN-1 可用于研究癌症。
T14991	CMS-121 CMS121	Acetyl-CoA Carboxylase	Metabolism
	CMS-121 是喹诺酮衍生物，对乙酰辅酶 A 羧化酶 1 具有抑制作用，具有口服活性。CMS-121具有保护 HT22 细胞免受缺血和氧化损伤的活性，EC50分别为7 nM 和200 nM。CMS-121具有强大的抗炎，抗氧化，神经保护和肾保护作用。
T5845	7ACC1 DEAC,香豆素D1421,Coumarin D 1421,7-(二乙胺基）-2-氧代-2-苯并吡喃-3-羧酸,7-(Diethylamino)coumarin-3-carboxylic acid,D 1421	Monocarboxylate transporter	Membrane transporter/Ion channel
	7ACC1 (D 142) 抑制表达MCT1和MCT4肿瘤细胞的乳酸涌入，能选择性干扰肿瘤微环境乳酸通量。
T7163	PF-05175157	Acetyl-CoA Carboxylase	Metabolism
	PF 05175157 是一种广谱的乙酰辅酶 A 羧化酶 (ACC) 抑制剂，对 ACC1 (human)，ACC2 (human)， ACC1 (rat) 和 ACC2 (rat) 具有抑制作用，IC50分别为 27.0, 33.0, 23.5 和 50.4 nM。
T1889	CP-640186 CP 640186	Acetyl-CoA Carboxylase	Metabolism
	CP-640186 是一种有效的乙酰辅酶 A 羧化酶 (ACC)抑制剂，抑制大鼠肝脏 ACC1 和大鼠骨骼肌 ACC2 的 IC50分别为 53 nM 和 61 nM。
T7184	Firsocostat ND-630,NDI-010976,GS-0976	Acetyl-CoA Carboxylase	Metabolism
	Firsocostat (GS-0976) 是有效的乙酰辅酶A 羧化酶 (ACC) 抑制剂，抑制人类 ACC1 和 ACC2 的IC50分别为2.1和6.1 nM。
T3622	CP-640186 hydrochloride CP 640186 HCl,盐酸CP-640186	Acetyl-CoA Carboxylase	Metabolism
	CP-640186 hydrochloride (CP 640186 HCl) 是膜渗透性的乙酰辅酶A 羧化酶（ACC）抑制剂，抑制大鼠肝脏ACC1和大鼠骨骼肌ACC2的IC50为53 nM 和61 nM。
TQ0243	ND-646	Acetyl-CoA Carboxylase	Metabolism
	ND-646 是乙酰辅酶 A 羧化酶（ACC）抑制剂，对重组 hACC1 和 hACC2的IC50分别为 3.5 nM 和 4.1 nM。
T4309	CIL56 CA3	Ferroptosis; ROS	Apoptosis; Immunology/Inflammation
	CIL56 (CA3) 是一种选择性铁死亡诱导剂，可通过产生铁依赖性活性氧来诱导细胞铁死亡。
T12062	MK-4074	Others	Others
	MK-4074 is a liver-specific acetyl-CoA carboxylase ACC1 and ACC2 inhibitor(IC50 of 3 nM).
T5046	Haloxyfop Haloxyfop Acid,(±)-Haloxyfop,吡氟氯禾灵	Others; Acetyl-CoA Carboxylase	Metabolism; Others
	Haloxyfop (Haloxyfop Acid) 是有效的芳氯氧苯氧丙酸除草剂，广泛应用于阔叶作物的野草。对玉米幼苗叶绿体中乙酰辅酶 A 羧化酶 (EC 6.4.1.2) 具有抑制作用，IC50为 0.5 μM，而对豌豆中该酶无影响。
T40675	CP-610431	Others	Others
	CP-610431 is a reversible, ATP-uncompetitive inhibitor of acetyl-CoA carboxylase (ACC), exhibiting isozyme nonselectivity. It inhibits both ACC1 and ACC2 with IC50 values of approximately 50 nM. CP-610431 offers potential application in metabolic syndrome research.

化合物

Cat.No: T61978

Target: Others

Cat.No: T63961

Target: Others

Cat.No: T14991

Synonym: CMS121

Target: Acetyl-CoA Carboxylase

Cat.No: T5845

Synonym: DEAC,香豆素D1421,Coumarin D 1421,7-(二乙胺基）-2-氧代-2-苯并吡喃-3-羧酸,7-(Diethylamino)coumarin-3-carboxylic acid,D 1421

Target: Monocarboxylate transporter

Cat.No: T7163

Target: Acetyl-CoA Carboxylase

Cat.No: T1889

Synonym: CP 640186

Target: Acetyl-CoA Carboxylase

Cat.No: T7184

Synonym: ND-630,NDI-010976,GS-0976

Target: Acetyl-CoA Carboxylase

CP-640186 hydrochloride

Cat.No: T3622

Synonym: CP 640186 HCl,盐酸CP-640186

Target: Acetyl-CoA Carboxylase

Cat.No: TQ0243

Target: Acetyl-CoA Carboxylase

Cat.No: T4309

Synonym: CA3

Target: Ferroptosis, ROS

Cat.No: T12062

Target: Others

Cat.No: T5046

Synonym: Haloxyfop Acid,(±)-Haloxyfop,吡氟氯禾灵

Target: Others, Acetyl-CoA Carboxylase

Cat.No: T40675

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-00330	Acetyl-CoA carboxylase Protein, Candida albicans, Recombinant (His) ACC1	Candida albicans	E. coli
	Acetyl-CoA carboxylase Protein, Candida albicans, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 67.3 kDa and the accession number is A0A1D8PRR7.
TMPH-00339	Acetyl-CoA carboxylase Protein, Candida glabrata, Recombinant (His) ACC1	Candida glabrata	E. coli
	Acetyl-CoA carboxylase Protein, Candida glabrata, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 67.2 kDa and the accession number is A0A0W0CTK3.
TMPY-04936	BCL2A1 Protein, Human, Recombinant (His) BFL1,ACC1,ACC-2,GRS,...	Human	E. coli
	B-cell lymphoma 2-related protein A1 (BCL2A1) is a member of the BCL-2 family of anti-apoptotic proteins that confers resistance to treatment with anti-cancer drugs. Immunohistochemical expression of Wnt11 and BCL2A1 in complete moles and normal villi. Bcl2 family proteins control mitochondrial apoptosis and its members exert critical cell type and differentiation stage-specific functions, acting as barriers against autoimmunity or transformation. Anti-apoptotic Bcl2a1/Bfl1/A1 is frequently der...
TMPH-03431	ACC1 Protein, S. cerevisiae, Recombinant (aa 217-775, His) Acetyl-CoA carboxylase,ACC,Fatty acid synthetase 3,...	Saccharomyces cerevisiae	E. coli
	Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase. Involved in the synthesis of very-long-chain fatty acid synthesis which is required to maintain a functional nuclear envelope. Required for acylation and vacuolar membrane association of VAC8 which is necessary to maintain a normal morphology of the vacuole. ACC1 Protein, S. cerevisiae, Recombinant (aa 217-775, His) is expressed in E. coli expression system with N-10xHis tag. The predicted m...
TMPH-03432	ACC1 Protein, S. cerevisiae, Recombinant (aa 2-581, His) mRNA transport-defective protein 7,Acetyl-CoA carboxylase,Fa...	Saccharomyces cerevisiae	E. coli
	Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase. Involved in the synthesis of very-long-chain fatty acid synthesis which is required to maintain a functional nuclear envelope. Required for acylation and vacuolar membrane association of VAC8 which is necessary to maintain a normal morphology of the vacuole. ACC1 Protein, S. cerevisiae, Recombinant (aa 2-581, His) is expressed in E. coli expression system with N-10xHis tag. The predicted mol...

重组蛋白

Acetyl-CoA carboxylase Protein, Candida albicans, Recombinant (His)

Cat.No: TMPH-00330

Species: Candida albicans

Expression System: E. coli

Acetyl-CoA carboxylase Protein, Candida glabrata, Recombinant (His)

Cat.No: TMPH-00339

Species: Candida glabrata

Expression System: E. coli

BCL2A1 Protein, Human, Recombinant (His)

Cat.No: TMPY-04936

Species: Human

Expression System: E. coli

ACC1 Protein, S. cerevisiae, Recombinant (aa 217-775, His)

Cat.No: TMPH-03431

Species: Saccharomyces cerevisiae

Expression System: E. coli

ACC1 Protein, S. cerevisiae, Recombinant (aa 2-581, His)

Cat.No: TMPH-03432

Species: Saccharomyces cerevisiae

Expression System: E. coli

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