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Search Results for " a-15 "
Targets Recommended: Others

588

抑制剂 & 化合物

110

天然产物

6

化合物库

6

TargetMol 试剂盒

215

重组蛋白

22

同位素标记化合物

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Cat. No. Product Name
L4150 新颖已知活性精选库

989 compounds
989 种百里挑一的活性化合物;
L5100 含氟化合物库

574 compounds
574 个含氟化合物的独特集合,可用于高通量筛选和高内涵筛选;
L1510 核受体化合物库

531 compounds
531 个核受体作用化合物的独特集合,可用于高通量筛选和高内涵筛选;
L2620 神经退行性疾病化合物库

2154 compounds
2154 种与神经退行性疾病相关的化合物,可用于高通量和高内涵筛选;
L6130 萜类天然产物库

622 compounds
622 种萜类天然产物的独特集合,可用于高通量筛选和高内涵筛选;
L6120 黄酮类天然产物库

514 compounds
514 种黄酮类天然产物的独特集合,可用于高通量筛选和高内涵筛选;

化合物库

新颖已知活性精选库
Cat.No: L4150
Compounds: 989
含氟化合物库
Cat.No: L5100
Compounds: 574
核受体化合物库
Cat.No: L1510
Compounds: 531
神经退行性疾病化合物库
Cat.No: L2620
Compounds: 2154
萜类天然产物库
Cat.No: L6130
Compounds: 622
黄酮类天然产物库
Cat.No: L6120
Compounds: 514
Cat. No. Product Name Form Specificity Of Inhibition
C0090 Mag Beads Streptavidin (1 μm)

链霉亲和素磁珠 (1 μm)

Suspension in bottle 免疫检测、分离蛋白;分离核酸、制备核酸探针;DN<em>A</em>-蛋白质相互作用研究;细胞分选与激活
C0092 Mag Beads Streptavidin (2.8 μm)

链霉亲和素磁珠 (2.8 μm)

Suspension in bottle 免疫检测、分离蛋白;分离核酸、制备核酸探针;DN<em>A</em>-蛋白质相互作用研究;细胞分选与激活
C0089 Mag Beads Streptavidin (300 nm)

链霉亲和素磁珠 (300 nm)

Suspension in bottle 免疫检测、分离蛋白;分离核酸、制备核酸探针;DN<em>A</em>-蛋白质相互作用研究;细胞分选与激活
C0093 Mag Beads Streptavidin (3 μm)

链霉亲和素磁珠 (3 μm)

Suspension in bottle 免疫检测、分离蛋白;分离核酸、制备核酸探针;DN<em>A</em>-蛋白质相互作用研究;细胞分选与激活
C0094 Mag Beads Streptavidin (5 μm)

链霉亲和素磁珠 (5 μm)

Suspension in bottle 免疫检测、分离蛋白;分离核酸、制备核酸探针;DN<em>A</em>-蛋白质相互作用研究;细胞分选与激活
C0091 Mag Beads Streptavidin (2 μm)

链霉亲和素磁珠 (2 μm)

Suspension in bottle 免疫检测、分离蛋白;分离核酸、制备核酸探针;DN<em>A</em>-蛋白质相互作用研究;细胞分选与激活

TargetMol 试剂盒

链霉亲和素磁珠 (1 μm)
Cat.No: C0090
链霉亲和素磁珠 (2.8 μm)
Cat.No: C0092
链霉亲和素磁珠 (300 nm)
Cat.No: C0089
链霉亲和素磁珠 (3 μm)
Cat.No: C0093
链霉亲和素磁珠 (5 μm)
Cat.No: C0094
链霉亲和素磁珠 (2 μm)
Cat.No: C0091
Cat. No. Product Name Target Signaling Pathways
T125334 15-Epi-Danshenol-A

Others Others
15-Epi-Danshenol-A 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T125334。
T36209 15-keto Prostaglandin A1

15-keto Prostaglandin A1

Others Others
Prostaglandin A1 (PGA1) was first isolated as a dehydration product of the PGE1 compounds found in human semen. 15-keto PGA1 is a metabolite of PGA1, produced by 15-hydroxy PG dehydrogenase. It can be produced from PGA1 in pig lung, trachea, aorta, and pulmonary artery tissue preparations. 15-keto PGA1, given at a concentration of 6 μM, causes vasoconstriction of rabbit lung that is comparable to that induced by angiotensin II.
T36208 15(R)-Pinane Thromboxane A2

15(R)-Pinane Thromboxane A2

Others Others
15(R)-Pinane thromboxane A2 is the (R)-epimer of pinane thromboxane A2 . 15(R)-PTA2 does not inhibit collagen-induced platelet aggregation (IC50s = 120-130 μM). It does not affect gastric tone in isolated rat gastric fundus when used at concentrations of 0.5 or 1.5 μg/ml and is less effective than PTA2 at inhibiting prostaglandin-induced contraction of isolated rat stomach muscle.
T125414 15-Stachen-19-ol; Erythroxylol A; 15-Beyeren-19-ol

Others Others
15-Stachen-19-ol; Erythroxylol A; 15-Beyeren-19-ol 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T125414,CAS号为 20107-90-8。
T2611 CCT 137690

CCT137690

Apoptosis; Aurora Kinase Apoptosis; Cell Cycle/Checkpoint; Chromatin/Epigenetic
CCT 137690是一种有口服活性的极光激酶抑制剂,对极光激酶A、B 和C 的IC50值分别为15、25 和19 nM。
T11634 IL-15-IN-1

IL Receptor; Interleukin Immunology/Inflammation
IL-15-IN-1是一种 IL-15依赖性细胞的选择性抑制剂(IC50:0.8 μM)。
TP1229 β-Amyloid (1-15)

Amyloid β-Protein (1-15)

Beta Amyloid Neuroscience
β-Amyloid (1-15) (Amyloid β-Protein (1-15)) 是 β-淀粉样蛋白片段,可用于研究阿尔茨海默病。
T11024 DHODH-IN-15

Dehydrogenase Metabolism
DHODH-IN-15是一种 A771726 的 hydroxyfurazan 类似物。DHODH-IN-15 是一种二氢乳清酸脱氢酶 (DHODH) 抑制剂,对大鼠肝脏 DHODH 的 IC50 为 11 μM。DHODH-IN-15 可用于类风湿关节炎。
T24488 MLS000545091

MLS-000545091,MLS 000545091

Others Others
MLS000545091 is a potent and selective human epithelial 15-lipoxygenase-2 mixed-type inhibitor.
T8794 4-MMPB

15-Lipoxygenase Inhibitor 1

Apoptosis; Others; Lipoxygenase Apoptosis; Metabolism; Others
4-MMPB (15-Lipoxygenase Inhibitor 1) 是一种选择性15-脂氧合酶抑制剂,其 IC50值为 18 μM,具有前列腺癌的研究潜力。它对大豆 15-脂氧合酶和人 15-脂氧合酶-1 的 IC50 分别为 19.5 μM 和 19.1 μM。
T22285 Carboprost

15(S)-15-Methyl Prostaglandin F2α,15-Methyl-PGF2α,卡前列素

Prostaglandin Receptor GPCR/G Protein; Immunology/Inflammation
Carboprost (15(S)-15-Methyl Prostaglandin F2α) 是一种前列腺素 F2α 的代谢稳定的合成类似物。它能够刺激子宫收缩并引起流产,可用于子宫收缩乏力引起的产后出血,以及在妊娠中期终止妊娠。
T3649 BGP-15

BGP15,BGP-15 2HCl

PARP Chromatin/Epigenetic; DNA Damage/DNA Repair
BGP-15 (BGP-15 2HCl) 是一种PARP 抑制剂,IC50和Ki 值分别为 120 和 57 μM,在缺血再灌注损伤后具有保护作用。
TP1214L β-Amyloid 15-21 acetate

Beta-Amyloid (15-21) acetate

Beta Amyloid Neuroscience
β-Amyloid 15-21 acetate (Beta-Amyloid(15-21) acetate) 是 Amyloid-β 肽的片段,可用于神经系统疾病的研究。该片段参与β折叠形成。
T8317 5'-Fluoroindirubinoxime

5'-FIO

FLT Angiogenesis; Tyrosine Kinase/Adaptors
5'-Fluoroindirubinoxime (5'-FIO) 是一种 Indirubin 的衍生物,是一种 FLT3 的抑制剂(IC50:15 nM)。
T19562 Polyethylene glycol 12-hydroxystearate

Solutol HS-15

Others Others
Polyethylene glycol 12-hydroxystearate (Solutol HS-15) 是一种通透性增强剂,是一种 Macrogol 15 羟基硬脂酸酯。
T7120 Cefetamet pivoxil hydrochloride

盐酸头孢他美酯,Ro 15-8075

Antibacterial; Antibiotic Microbiology/Virology
Cefetamet pivoxil hydrochloride (Ro 15-8075) 是一种可口服的头孢类抗生素。
T2633 GSK429286A

RHO-15

ROCK Cell Cycle/Checkpoint; Cytoskeletal Signaling; Stem Cells
GSK429286A (RHO-15) 是一种选择性ROCK1/2抑制剂,IC50值为14 和 63 nM。
T76892 Ordesekimab

AMG 714,PRV-015

IL Receptor Immunology/Inflammation
Ordesekimab (AMG 714) 是一种人 IgG1κ 抗 IL-15 (Interleukin Related) 单克隆抗体。Ordesekimab 竞争性与 IL-15 结合,会抑制 IL-15 与 IL-2Rβ 和 IL-15 受体复合物的共同 γ 链的相互作用,却不与 IL-15Rα 链发生反应。Ordesekimab 可用于研究无反应性乳糜泻 (NRCD) 。
T60507 Utreloxastat

EPI 857,PTC857

Lipoxygenase Metabolism
Utreloxastat (PTC857) 是一种新型 15-脂氧合酶抑制剂,可用于研究肌萎缩侧索硬化症 。
T64391 Antiproliferative agent-15

Others Others
Antiproliferative agent-15是一种具有抗癌活性的试剂。Antiproliferative agent-15对人结肠癌(HCT116和HCT15)和脑癌(LN-229和GBM-10)具有抗增殖活性。
T38163 ML-148

Dehydrogenase Metabolism
ML-148 是 15-羟基前列腺素脱氢酶 (15-PGDH, IC50 = 56 nM) 的特异性抑制剂。 ML-148 可用于分析一组相关的脱氢酶或还原酶以及有关前列腺素信号通路的研究。
T3153 Serabelisib

TAK-117,INK1117,MLN1117

PI3K; mTOR PI3K/Akt/mTOR signaling
Serabelisib (INK1117) 是选择性的 p110α 抑制剂,其 IC50=15 nM。
T22984 MJ 15

Cannabinoid Receptor GPCR/G Protein
MJ 15 是一种具有特异性的 CB1 受体拮抗剂,可用于研究肥胖引发的疾病。
T21902 ML351

Lipoxygenase Metabolism
ML351 是一种高度特异的15-LOX-1抑制剂,其 IC50=200 nM。它对 T1D 非肥胖糖尿病小鼠模型的血糖异常和β细胞氧化应激有抑制作用。它对相关同工酶 (5-LOX、血小板 12-LOX、15-LOX-2、绵羊 COX-1 和人 COX-2) 表现出良好的选择性(>250倍)。
TP1246L ACTH (22-39) acetate

ACTH (22-39) acetate (37548-29-1 Free base)

Others Others
ACTH (22-39) acetate 是促肾上腺皮质激素 (ACTH) 的片段,在 N 末端的第 3 位和第 15 位含有两个脯氨酸残基。
T6420 BMS-707035

N-[(4-氟苯基)甲基1,6-二氢-5-羟基-1-甲基-6-氧代-2-(四氢-1,1-二氧-2H-1,2-噻嗪-2-基)-4-嘧啶甲酰胺

HIV Protease Microbiology/Virology; Proteases/Proteasome
BMS707035是一种 HIV-1 整合酶抑制剂,IC50为15 nM。
T2696 PRT062607 hydrochloride

PRT062607 (P505-15, BIIB057) HCl,P505-15 Hydrochloride

MLK; Syk; Src Angiogenesis; MAPK; Tyrosine Kinase/Adaptors
PRT062607 hydrochloride (P505-15 Hydrochloride) 是纯化的 Syk 抑制剂,IC50=1-2 nM。
T67908 ThioLox

Lipoxygenase Metabolism
ThioLox 是一种竞争性 15-脂氧合酶-1 (15-LOX-1) 抑制剂(IC50值为12 μM)。ThioLox 显示抗炎和神经保护特性。具有抗炎和神经保护作用,对谷氨酸毒性有很强的保护作用。
T5171 Treprostinil Sodium

曲前列尼尔钠,UT-15

VEGFR; c-RET; Prostaglandin Receptor Angiogenesis; Apoptosis; GPCR/G Protein; Immunology/Inflammation; Tyrosine Kinase/Adaptors
Treprostinil Sodium (UT-15) 是有效的 DP1、IP 和 EP2 激动剂,EC50分别为0.6、1.9 和 6.2 nM。
T1966 Tubastatin A

Tubastatin A BASE

Apoptosis; HDAC; Autophagy Apoptosis; Autophagy; Chromatin/Epigenetic; DNA Damage/DNA Repair
Tubastatin A (Tubastatin A BASE) 是一种选择性 HDAC6抑制剂,IC50值为 15 nM。
T16844 Sarmazenil

R-154513,Ro 15-3505

GABA Receptor Membrane transporter/Ion channel; Neuroscience
Sarmazenil (Ro 15-3505) 是苯二氮卓受体部分反向激动剂,具有促惊厥作用,可用于研究慢性肝性脑病 (HE) 。
T6126 JNJ-7706621

JNJ 7706621

Apoptosis; CDK; Aurora Kinase Apoptosis; Cell Cycle/Checkpoint; Chromatin/Epigenetic
JNJ-7706621 是一种aurora kinase 抑制剂,有效抑制CDK1和CDK2,对CDK1,CDK2,aurora-Aaurora-B 的IC50值分别为 9 nM,3 nM,11 nM 和 15 nM。
T37992 15-Methyl Palmitic Acid

15-Methylpalmitic acid,15-Methylhexadecanoic acid

15-methyl Palmitic Acid 是一种一种甲基化脂肪酸,广泛存在于动物脂质中,可能于调节脂肪代谢有关。
T2121 SW033291

Dehydrogenase Metabolism
SW033291 是有效的15-PGDH 抑制剂,与15-PGDH 亲和力高,Ki 为 0.1 nM。它增加骨髓和其他组织中前列腺素 PGE2 的水平。它还可促进组织再生。
T5318 666-15

CREB inhibitor

Epigenetic Reader Domain Chromatin/Epigenetic
666-15 (CREB inhibitor) 是一种选择性CREB 抑制剂,IC50为 81 nM,可抑制乳腺癌异种移植模型中的肿瘤生长。
T6161 Tubastatin A Hydrochloride

TSA HCl,Tubastatin A HCl

Apoptosis; HDAC; Autophagy Apoptosis; Autophagy; Chromatin/Epigenetic; DNA Damage/DNA Repair
Tubastatin A Hydrochloride (TSA HCl) 是一种选择性的 HDAC6抑制剂,IC50值为 15 nM,对其选择性是 HDAC8 外的其他亚型的 1000 多倍。
T20561L BPC 157 acetate(137525-51-0 free base)

BPC157 acetate,BPC-157 acetate,Bpc 15 acetate,Bpc15 acetate,Bpc-15 acetate

Others Others
BPC 157 acetate(137525-51-0 free base) 是一种具有保肝作用的胃肽 (BPC) 的 15 个氨基酸片段。
T7945 SU14813

VEGFR; PDGFR; c-Kit Angiogenesis; Tyrosine Kinase/Adaptors
SU14813 是一种多靶点受体酪氨酸激酶抑制剂,能够抑制 VEGFR2 (IC50:50 nM),VEGFR1 (IC50:2 nM),PDGFRβ (IC50:4 nM),KIT (IC50:15 nM)。
T0393 Anastrozole

阿那曲唑,ZD1033

Aromatase Endocrinology/Hormones
Anastrozole (ZD1033) 是芳香酶的选择性抑制剂,能够抑制胎盘芳香化酶(IC50:15 nM)。
T7944 VPS34 inhibitor 1 (Compound 19, PIK-III analogue)

PIK-III analogue

PI3K PI3K/Akt/mTOR signaling
VPS34 inhibitor 1 (Compound 19, PIK-III analogue) (PIK-III analogue) 是一种有效的选择性 VPS34抑制剂( IC50 : 15 nM)。
T36201L AZD5582 TFA

AZD5582 TFA(1258392-53-8 free base)

Apoptosis; IAP Apoptosis
AZD5582 TFA 是一种有效的 IAP 拮抗剂,可与 cIAP1,cIAP2 和 XIAP 的 BIR3 结构域结合, IC50 值分别为 15,21,15 nM。AZD5582 TFA可诱导细胞凋亡。
T6785 BI-847325

Apoptosis; MEK; Aurora Kinase Apoptosis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; MAPK
BI847325是MEK 和极光激酶 (AK)的一种选择性双重抑制剂, 对人类MEK2和AK-C 的IC50值分别为4和15 nM。
TP1127L1 Nemifitide acetate(173240-15-8 free base)

INN 00835 acetate

5-HT Receptor GPCR/G Protein; Neuroscience
Nemifitide acetate(173240-15-8 free base) (INN 00835 acetate) 是一种合成的五肽抗抑郁药,具有快速起效的潜力。它是黑色素细胞抑制因子 (MIF) 的肽类似物。
T17203 UNC0224

Histone Methyltransferase Chromatin/Epigenetic
UNC0224 是 G9a 的特异性抑制剂,Ki 为 2.6 nM,IC50 为 15 nM。 UNC0224 还有效抑制 GLP,IC50 值为 20-58 nM。
T21022 Deacylketoconazole

Deacyl ketoconazole,脱乙酰酮康唑

Antifungal Microbiology/Virology
Deacylketoconazole (Deacyl ketoconazole) 是一种酮康唑衍生物,也是一种抗真菌剂。 脱酰基酮康唑对恶性疟原虫的活性是酮康唑的 15 至 50 倍。
T10693 CB-6644

Others Others
CB-6644 是 RUVBL1/2的选择性复合体抑制剂,能够抑制 RUVBL1/2 的 ATP 酶活性(IC50:15 nM)。它具有抗癌作用。
T37806 JNJ-55308942

P2X Receptor Membrane transporter/Ion channel; Neuroscience
JNJ-55308942 是 P2X7 功能性的选择性脑渗透拮抗剂,对 hP2X7 和 rP2X7 的 IC50 分别为 10 和 15 nM,Kis 分别为 7.1 和 2.9 nM。
T6484 EI1

KB-145943,Ezh2 inhibitor

Apoptosis; Histone Methyltransferase Apoptosis; Chromatin/Epigenetic
EI1 (Ezh2 inhibitor) 是一种EZH2抑制剂,能够作用于 EZH2 (WT) 和 EZH2 (Y641F),IC50值分别为 15 nM 和 13 nM。
T8950 CAY10698

Lipoxygenase Metabolism
CAY10698 是选择性的12-Lipoxygenase (12-LOX)抑制剂,IC50=5.1 μM。它对 5-LOX、15-LOX-1、15-LOX-2 和 COX-1/2 无活性。
T6171 BI-D1870

S6 Kinase; Autophagy Autophagy; MAPK; PI3K/Akt/mTOR signaling
BI-D1870 是一种可渗透细胞和透过血脑屏障的的 ATP 竞争性核糖体 S6 激酶抑制剂,抑制 RSK1、RSK2、RSK3和 RSK4 的 IC50值分别为 31 nM、24 nM、18 nM 和15 nM。

化合物

15-Epi-Danshenol-A
Cat.No: T125334
Synonym:
Target: Others
15-keto Prostaglandin A1
Cat.No: T36209
Synonym: 15-keto Prostaglandin A1
Target: Others
15(R)-Pinane Thromboxane A2
Cat.No: T36208
Synonym: 15(R)-Pinane Thromboxane A2
Target: Others
15-Stachen-19-ol; Erythroxylol A; 15-Beyeren-19-ol
Cat.No: T125414
Synonym:
Target: Others
CCT 137690
Cat.No: T2611
Synonym: CCT137690
Target: Apoptosis, Aurora Kinase
IL-15-IN-1
Cat.No: T11634
Synonym:
Target: IL Receptor, Interleukin
β-Amyloid (1-15)
Cat.No: TP1229
Synonym: Amyloid β-Protein (1-15)
Target: Beta Amyloid
DHODH-IN-15
Cat.No: T11024
Synonym:
Target: Dehydrogenase
MLS000545091
Cat.No: T24488
Synonym: MLS-000545091,MLS 000545091
Target: Others
4-MMPB
Cat.No: T8794
Synonym: 15-Lipoxygenase Inhibitor 1
Target: Apoptosis, Others, Lipoxygenase
Carboprost
Cat.No: T22285
Synonym: 15(S)-15-Methyl Prostaglandin F2α,15-Methyl-PGF2α,卡前列素
Target: Prostaglandin Receptor
BGP-15
Cat.No: T3649
Synonym: BGP15,BGP-15 2HCl
Target: PARP
β-Amyloid 15-21 acetate
Cat.No: TP1214L
Synonym: Beta-Amyloid (15-21) acetate
Target: Beta Amyloid
5'-Fluoroindirubinoxime
Cat.No: T8317
Synonym: 5'-FIO
Target: FLT
Polyethylene glycol 12-hydroxystearate
Cat.No: T19562
Synonym: Solutol HS-15
Target: Others
Cefetamet pivoxil hydrochloride
Cat.No: T7120
Synonym: 盐酸头孢他美酯,Ro 15-8075
Target: Antibacterial, Antibiotic
GSK429286A
Cat.No: T2633
Synonym: RHO-15
Target: ROCK
Ordesekimab
Cat.No: T76892
Synonym: AMG 714,PRV-015
Target: IL Receptor
Utreloxastat
Cat.No: T60507
Synonym: EPI 857,PTC857
Target: Lipoxygenase
Antiproliferative agent-15
Cat.No: T64391
Synonym:
Target: Others
ML-148
Cat.No: T38163
Synonym:
Target: Dehydrogenase
Serabelisib
Cat.No: T3153
Synonym: TAK-117,INK1117,MLN1117
Target: PI3K, mTOR
MJ 15
Cat.No: T22984
Synonym:
Target: Cannabinoid Receptor
ML351
Cat.No: T21902
Synonym:
Target: Lipoxygenase
ACTH (22-39) acetate
Cat.No: TP1246L
Synonym: ACTH (22-39) acetate (37548-29-1 Free base)
Target: Others
BMS-707035
Cat.No: T6420
Synonym: N-[(4-氟苯基)甲基1,6-二氢-5-羟基-1-甲基-6-氧代-2-(四氢-1,1-二氧-2H-1,2-噻嗪-2-基)-4-嘧啶甲酰胺
Target: HIV Protease
PRT062607 hydrochloride
Cat.No: T2696
Synonym: PRT062607 (P505-15, BIIB057) HCl,P505-15 Hydrochloride
Target: MLK, Syk, Src
ThioLox
Cat.No: T67908
Synonym:
Target: Lipoxygenase
Treprostinil Sodium
Cat.No: T5171
Synonym: 曲前列尼尔钠,UT-15
Target: VEGFR, c-RET, Prostaglandin Receptor
Tubastatin A
Cat.No: T1966
Synonym: Tubastatin A BASE
Target: Apoptosis, HDAC, Autophagy
Sarmazenil
Cat.No: T16844
Synonym: R-154513,Ro 15-3505
Target: GABA Receptor
JNJ-7706621
Cat.No: T6126
Synonym: JNJ 7706621
Target: Apoptosis, CDK, Aurora Kinase
15-Methyl Palmitic Acid
Cat.No: T37992
Synonym: 15-Methylpalmitic acid,15-Methylhexadecanoic acid
Target:
SW033291
Cat.No: T2121
Synonym:
Target: Dehydrogenase
666-15
Cat.No: T5318
Synonym: CREB inhibitor
Target: Epigenetic Reader Domain
Tubastatin A Hydrochloride
Cat.No: T6161
Synonym: TSA HCl,Tubastatin A HCl
Target: Apoptosis, HDAC, Autophagy
BPC 157 acetate(137525-51-0 free base)
Cat.No: T20561L
Synonym: BPC157 acetate,BPC-157 acetate,Bpc 15 acetate,Bpc15 acetate,Bpc-15 acetate
Target: Others
SU14813
Cat.No: T7945
Synonym:
Target: VEGFR, PDGFR, c-Kit
Anastrozole
Cat.No: T0393
Synonym: 阿那曲唑,ZD1033
Target: Aromatase
VPS34 inhibitor 1 (Compound 19, PIK-III analogue)
Cat.No: T7944
Synonym: PIK-III analogue
Target: PI3K
AZD5582 TFA
Cat.No: T36201L
Synonym: AZD5582 TFA(1258392-53-8 free base)
Target: Apoptosis, IAP
BI-847325
Cat.No: T6785
Synonym:
Target: Apoptosis, MEK, Aurora Kinase
Nemifitide acetate(173240-15-8 free base)
Cat.No: TP1127L1
Synonym: INN 00835 acetate
Target: 5-HT Receptor
UNC0224
Cat.No: T17203
Synonym:
Target: Histone Methyltransferase
Deacylketoconazole
Cat.No: T21022
Synonym: Deacyl ketoconazole,脱乙酰酮康唑
Target: Antifungal
CB-6644
Cat.No: T10693
Synonym:
Target: Others
JNJ-55308942
Cat.No: T37806
Synonym:
Target: P2X Receptor
EI1
Cat.No: T6484
Synonym: KB-145943,Ezh2 inhibitor
Target: Apoptosis, Histone Methyltransferase
CAY10698
Cat.No: T8950
Synonym:
Target: Lipoxygenase
BI-D1870
Cat.No: T6171
Synonym:
Target: S6 Kinase, Autophagy
Cat. No. Product Name Target Signaling Pathways
T2870 Matrine

Vegard,苦参碱,Matridin-15-one,Matrinium,α-Matrine,(+)-Matrine

Mitophagy; Ferroptosis; Opioid Receptor; Autophagy Apoptosis; Autophagy; Endocrinology/Hormones; GPCR/G Protein; Neuroscience
Matrine (Vegard) 是一种从槐属植物中分离出来的生物碱,可作为一种κ阿片受体激动剂,有抗肿瘤活性。
T8002 3-Hydroxycoumarin

Lipoxygenase Metabolism
3-hydroxycoumarin 是一种 15-LOX-1的有效氧化还原抑制剂,近期被证明能保护海胆生殖细胞免受紫外线 B 的损伤。
T14865 Carboprost tromethamine

Prostaglandin Receptor GPCR/G Protein; Immunology/Inflammation
Carboprost tromethamine 是合成的前列腺素 F2α的15-甲基类似物,能有效促进子宫的规律收缩,显着减少产中及产后出血量。
T6680 Staurosporine

Antibiotic AM-2282,星形孢菌素,AM-2282,CGP 41251,星孢菌素

Apoptosis; PKA; Antibacterial; Antibiotic; Src; PKC; Antifungal Angiogenesis; Apoptosis; Chromatin/Epigenetic; Cytoskeletal Signaling; Microbiology/Virology; Tyrosine Kinase/Adaptors
Staurosporine (AM-2282) 是一种蛋白激酶抑制剂,对 PKC、PKA、c-Fgr、Phosphorylase kinase 和 TAOK2 均有抑制活性 (IC50=6/15/2/3/3000 nM),具有 ATP 竞争性和非选择性。Staurosporine 也可以诱导凋亡。
T3030 L-Sophoridine

L-槐定碱,Sophoridine,Matridin-15-one

Others Others
L-Sophoridine (Matridin-15-one) 一种从药用植物中提取的天然产物,具有多种药理作用,包括抗Y 作用,可在体外和体内选择性诱导多种人体Y 细胞凋亡;然而,其作用机制需要进一步阐述。
T37974 (S)-Coriolic acid

13(S)-HODE

Lipoxygenase; Mitochondrial Metabolism; PPAR DNA Damage/DNA Repair; Metabolism
(S)-Coriolic acid (13(S)-HODE) 是一种重要的细胞内信号剂,是亚油酸与植物和哺乳动物脂氧合酶反应生成的,在各种生物系统中参与细胞增殖和分化。(S)-Coriolic acid 在 1 μM 左右时,它能抑制肿瘤细胞与血管内皮的粘附,能下调 IRGpIIb/IIIa 受体的表达。(S)-Coriolic acid 是15-脂氧合酶 (15-LOX) 代谢产物,常作为内源性配体激活 PPARγ。(S)-Coriolic acid 诱导线粒体功能障碍 和气道上皮损伤。
T8049 Pentadecanoic acid

Others; Endogenous Metabolite Metabolism; Others
Pentadecanoic acid 是一个具有 15 个碳主链的饱和脂肪酸。
T5214 Cholesteryl linoleate

CE(18:2(9Z,12Z)),Cholesterol Linoleate,Linoleic Acid cholesteryl ester,胆甾烯基亚油酸酯

Others; Endogenous Metabolite Metabolism; Others
Cholesteryl linoleate 是低密度脂蛋白和动脉粥样硬化病变中主要的胆固醇酯。它存在于 LDL 中的胆固醇酯,利用 LDL 受体相关蛋白转移到表达 15-脂氧合酶的巨噬细胞和 CHO 细胞的质膜,被氧化形成胆固醇亚油酸氢过氧化物。
TN6864 Prosaikogenin F

前柴胡皂苷F

Others Others
Prosaikogenin F ((2R,3R,4S,5R,6R)-2-{[(1S,2R,4S,5R,8R,9S,10R,13S,14R,17S,18R)-2-hydroxy-9-(hydroxymethyl)-4,5,9,13,20,20-hexamethyl-24-oxahexacyclo[15.5.2.01,1?.0?,1?.0?,1?.0?,13]tetracos-15-en-10-yl]oxy}-6-methyloxane-3,4,5-triol) 是一种单糖苷,具有溶血和抗癌特性。
T2783 Methyl dihydrojasmonate

Methyl Dihydrojasmonate,Kharismal,Hedione,二氢茉莉酮酸甲酯

Others Others
Methyl dihydrojasmonate (Kharismal) 是一种香料成分,具有茉莉花香气,常用于许多香料混合物中。
TN1787 Isomucronulatol 7-O-glucoside

Isomucronulatol 7-O-beta-glucoside,黄芪紫檀烷苷,3-羟基-9,10-二甲氧基紫檀烷

Others Others
Isomucronulatol 7-O-beta-glucoside 具有潜在的抗炎活性,在体外对 LPS 刺激产生的 IL-12 p40 表现出微弱的抑制作用。
T6862 Isatin

Pseudoisatin,板蓝根,Indoline-2,3-dione,2,3-Indolinedione

Apoptosis; MAO; Monoamine Oxidase Apoptosis; Metabolism; Neuroscience
Isatin (2,3-Indolinedione) 是一种单胺氧化酶抑制剂,IC50为3 μM。它也可作为心钠肽刺激和一氧化氮刺激的鸟苷酸环化酶活性的拮抗剂,显示对血清素系统有影响。
TN1516 Cnidicin

蛇床素,4,9-双[(3-甲基-2-丁烯-1-基)氧基]-7H-呋喃并[3,2-G][1]苯并吡喃-7-酮

NOS; NO Synthase Immunology/Inflammation
Cnidicin 是一种香豆素,对肥大细胞脱颗粒及 RAW 264.7 细胞产生一氧化氮具有抑制作用。
T5980 2-Ketoglutaric acid

α-酮戊二酸,alpha-酮戊二酸

Tyrosinase; Endogenous Metabolite Metabolism; Proteases/Proteasome
2-Ketoglutaric acid 是 Krebs 循环的中间体,可以产生 ATP 或 GTP 。2-Ketoglutaric acid 还充当氮同化反应的主要碳骨架。2-Ketoglutaric acid 是酪氨酸酶(tyrosinase)的可逆抑制剂 (IC50=15 mM)。
T5S1897 Linderalactone

Apoptosis; Others; JAK Angiogenesis; Apoptosis; Chromatin/Epigenetic; JAK/STAT signaling; Others; Stem Cells
Linderalactone 是从乌药中分离出来的一种倍半萜烯内酯,通过调节凋亡相关蛋白的表达和抑制 JAK/STAT 信号通路来抑制癌细胞生长。它以 IC50值为 15 µM 来抑制肺癌 A-549 细胞的增殖。
T3929 Kaurenoic acid

Kauren-19-Oic Acid,异贝壳杉烯酸,kaurenoate,kaur-16-en-18-oic acid

Others Others
Kaurenoic acid (kaurenoate) 是一种二萜,来源于 Sphagneticola trilobata 中,可以抑制细胞因子的产生和激活 NO–cyclic GMP–PKG–ATP- 敏感型钾通道信号通路,并抑制炎症疼痛。
T38299 Tunicamycin V

Others Others
Tunicamycin 15:1 is a mixture of tunicamycin structural isomers that contains a 15-carbon N-acyl chain with variable branching patterns.References Tunicamycin 15:1 is a mixture of tunicamycin structural isomers that contains a 15-carbon N-acyl chain with variable branching patterns. References
T27651 JBIR-15

Others Others
JBIR-15, a fungal metabolite, demonstrates antifungal activity against C.albicans.
TN5947 3-Dehydro-15-deoxoeucosterol

17,23-Epoxy-29-hydroxy-27-norlanost-8-ene-3,24-dione

3-Dehydro-15-deoxoeucosterol is a natural product from Scilla scilloides.
TN2635 15-Demethylplumieride

Others Others
15-Demethylplumieride is a quality control index of Plumeriarubra L.
T22473 15-deoxy-Δ-12,14-Prostaglandin J2

Others Others
15-deoxy-Δ-12,14-Prostaglandin J2 is a PPAagonist.
TN4030 Eudesm-4(15)-ene-3alpha,11-diol

Eudesm-4(15)-ene-3alpha,11-diol 是一种来源于Eudesm-4(15)-ene-3alpha,11-diol 的化合物。
TN2636 15-Deoxoeucosterol

Others Others
15-Deoxoeucosterol是一种天然产物,属于天门冬科蓝瑰花属,其产品编号为 TN2636,CAS号为 81241-53-4。15-Deoxoeucosterol可用作对照参考。
TMA0164 15-Hydroxydehydroabietic acid

P450; Antifection Metabolism; Microbiology/Virology
15-Hydroxydehydroabietic acid exhibits a promising alpha-glucosidase inhibitory activity, it also shows significant antibacterial activities.
T10045 15-Acetyl-deoxynivalenol

Others Others
15-Acetyl-deoxynivalenol is a highly toxic trichothecene found in cereals and exhibits toxicity to HepG2 cells.
TN6526 15-Methoxy-16-oxo-15,16H-strictic acid

15-Methoxy-16-oxo-15,16H-strictic acid是一种天然产物,属于菊科蚤草属,其产品编号为 TN6526,CAS号为 1356388-38-9。15-Methoxy-16-oxo-15,16H-strictic acid可用作对照参考。
TN6525 15-Deoxypulic acid

15-Deoxypulic acid是一种天然产物,属于菊科蚤草属,其产品编号为 TN6525,CAS号为 95523-05-0。15-Deoxypulic acid可用作对照参考。
TN2638 15-Hydroxy-7-oxodehydroabietic acid

Others Others
15-Hydroxy-7-oxodehydroabietic acid是一种天然产物,属于松科松属,其产品编号为 TN2638,CAS号为 95416-25-4。15-Hydroxy-7-oxodehydroabietic acid可用作对照参考。
TN2648 16-Nor-15-oxodehydroabietic acid

Others Others
16-Nor-15-oxodehydroabietic acid is a natural product from Pinus massoniana.
TN6478 (-)-Cadin-4,10(15)-dien-11-oic acid

(-)-Cadin-4,10(15)-dien-11-oic acid是一种天然产物,属于天南星科菖蒲属,其产品编号为 TN6478,CAS号为 1124353-23-6。(-)-Cadin-4,10(15)-dien-11-oic acid可用作对照参考。
TMA0692 Diosbulbin G

山药

Others Others
Diosbulbin G是一种天然产物,属于薯蓣科薯蓣属,其产品编号为 TMA0692,CAS号为 67567-15-1。Diosbulbin G可用作对照参考。
TN5624 Adenostemmoside A

Adenostemmoside A 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5624,CAS号为 130217-15-1。
T10664 Calcium 2-oxoglutarate

Others; Tyrosinase Others; Proteases/Proteasome
Calcium 2-oxoglutarate is an intermediate in the production of GTP or ATP in the Krebs cycle. It is a reversible inhibitor of tyrosinase (IC50: 15 mM).
TN2640 15-Methoxymkapwanin

Others Others
15-Methoxymkapwanin is a natural product from Dodonaea angustifolia.
TN5383 Ugandenial A

Ugandenial A 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5383,CAS号为 1175880-15-5。
TN5811 Pilosol A

Pilosol A 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5811,CAS号为 501086-15-3。
TN5705 Muricarpone B

Muricarpone B 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5705,CAS号为 886226-15-9。
TN6288 Karavilagenin F

Karavilagenin F 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6288,CAS号为 1639024-15-9。
TN6018 Epistephamiersine

Epistephamiersine是一种天然产物,属于防己科千金藤属,其产品编号为 TN6018,CAS号为 52389-15-8。Epistephamiersine可用作对照参考。
T39003 4',2-Dihydroxy-4,6-dimethoxydihydrochalcone

Others Others
4',2-Dihydroxy-4,6-dimethoxydihydrochalcone, an estrogen agonist, exhibits a significant binding affinity for the estrogen receptor in bovine uterine tissue, with an IC50 value of 15 μM.
TN7391 Caffeoylcalleryanin

Others Others
Caffeoylcalleryanin demonstrated potent inhibitory activity against 15-lipoxygenase (15-LOX), with an IC50 value of 1.59 μM. Furthermore, ethanol extract from A. pulchra leaves (EEAPL) was found to contain compounds exhibiting antiviral properties, particularly effective against Dengue virus type 2 (DENV-2). Among these compounds, Caffeoylcalleryanin emerged as the most potent anti-DENV-2 agent, achieving a selectivity index (SI) of 20.0.
TN2637 15-Dihydroepioxylubimin

Others Others
15-Dihydroepioxylubimin 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN2637,CAS号为 129214-59-1。
TN6696 (+)-D-3-Carene

(+)-D-3-Carene 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6696,CAS号为 498-15-7。
TN5928 γ-Asarone

soasarone,γ-细辛醚

γ-Asarone 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5928,CAS号为 5353-15-1。
TN6462 Isolappaol C

Isolappaol C 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6462,CAS号为 929905-15-7。
TN6158 Isomurrayafoline B

Isomurrayafoline B 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6158,CAS号为 107903-15-1。
TN6126 Pipoxide chlorohydrin

Pipoxide chlorohydrin 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6126,CAS号为 29228-15-7。
TN5987 Betulinic acid palmitate

Betulinic acid palmitate 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5987,CAS号为 19833-15-9。
TN2690 2',3,5,7-Tetrahydroxyflavone

Others Others
2',3,5,7-Tetrahydroxyflavone 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN2690,CAS号为 480-15-9。
TN3261 8(14),15-Isopimaradiene-3,18-diol

Others Others
8(14),15-Isopimaradiene-3,18-diol 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN3261,CAS号为 59219-64-6。
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天然产物

Matrine
Cat.No: T2870
Synonym: Vegard,苦参碱,Matridin-15-one,Matrinium,α-Matrine,(+)-Matrine
Target: Mitophagy, Ferroptosis, Opioid Receptor, Autophagy
3-Hydroxycoumarin
Cat.No: T8002
Synonym:
Target: Lipoxygenase
Carboprost tromethamine
Cat.No: T14865
Synonym:
Target: Prostaglandin Receptor
Staurosporine
Cat.No: T6680
Synonym: Antibiotic AM-2282,星形孢菌素,AM-2282,CGP 41251,星孢菌素
Target: Apoptosis, PKA, Antibacterial, Antibiotic, Src, PKC, Antifungal
L-Sophoridine
Cat.No: T3030
Synonym: L-槐定碱,Sophoridine,Matridin-15-one
Target: Others
(S)-Coriolic acid
Cat.No: T37974
Synonym: 13(S)-HODE
Target: Lipoxygenase, Mitochondrial Metabolism, PPAR
Pentadecanoic acid
Cat.No: T8049
Synonym:
Target: Others, Endogenous Metabolite
Cholesteryl linoleate
Cat.No: T5214
Synonym: CE(18:2(9Z,12Z)),Cholesterol Linoleate,Linoleic Acid cholesteryl ester,胆甾烯基亚油酸酯
Target: Others, Endogenous Metabolite
Prosaikogenin F
Cat.No: TN6864
Synonym: 前柴胡皂苷F
Target: Others
Methyl dihydrojasmonate
Cat.No: T2783
Synonym: Methyl Dihydrojasmonate,Kharismal,Hedione,二氢茉莉酮酸甲酯
Target: Others
Isomucronulatol 7-O-glucoside
Cat.No: TN1787
Synonym: Isomucronulatol 7-O-beta-glucoside,黄芪紫檀烷苷,3-羟基-9,10-二甲氧基紫檀烷
Target: Others
Isatin
Cat.No: T6862
Synonym: Pseudoisatin,板蓝根,Indoline-2,3-dione,2,3-Indolinedione
Target: Apoptosis, MAO, Monoamine Oxidase
Cnidicin
Cat.No: TN1516
Synonym: 蛇床素,4,9-双[(3-甲基-2-丁烯-1-基)氧基]-7H-呋喃并[3,2-G][1]苯并吡喃-7-酮
Target: NOS, NO Synthase
2-Ketoglutaric acid
Cat.No: T5980
Synonym: α-酮戊二酸,alpha-酮戊二酸
Target: Tyrosinase, Endogenous Metabolite
Linderalactone
Cat.No: T5S1897
Synonym:
Target: Apoptosis, Others, JAK
Kaurenoic acid
Cat.No: T3929
Synonym: Kauren-19-Oic Acid,异贝壳杉烯酸,kaurenoate,kaur-16-en-18-oic acid
Target: Others
Tunicamycin V
Cat.No: T38299
Synonym:
Target: Others
JBIR-15
Cat.No: T27651
Synonym:
Target: Others
3-Dehydro-15-deoxoeucosterol
Cat.No: TN5947
Synonym: 17,23-Epoxy-29-hydroxy-27-norlanost-8-ene-3,24-dione
Target:
15-Demethylplumieride
Cat.No: TN2635
Synonym:
Target: Others
15-deoxy-Δ-12,14-Prostaglandin J2
Cat.No: T22473
Synonym:
Target: Others
Eudesm-4(15)-ene-3alpha,11-diol
Cat.No: TN4030
Synonym:
Target:
15-Deoxoeucosterol
Cat.No: TN2636
Synonym:
Target: Others
15-Hydroxydehydroabietic acid
Cat.No: TMA0164
Synonym:
Target: P450, Antifection
15-Acetyl-deoxynivalenol
Cat.No: T10045
Synonym:
Target: Others
15-Methoxy-16-oxo-15,16H-strictic acid
Cat.No: TN6526
Synonym:
Target:
15-Deoxypulic acid
Cat.No: TN6525
Synonym:
Target:
15-Hydroxy-7-oxodehydroabietic acid
Cat.No: TN2638
Synonym:
Target: Others
16-Nor-15-oxodehydroabietic acid
Cat.No: TN2648
Synonym:
Target: Others
(-)-Cadin-4,10(15)-dien-11-oic acid
Cat.No: TN6478
Synonym:
Target:
Diosbulbin G
Cat.No: TMA0692
Synonym: 山药
Target: Others
Adenostemmoside A
Cat.No: TN5624
Synonym:
Target:
Calcium 2-oxoglutarate
Cat.No: T10664
Synonym:
Target: Others, Tyrosinase
15-Methoxymkapwanin
Cat.No: TN2640
Synonym:
Target: Others
Ugandenial A
Cat.No: TN5383
Synonym:
Target:
Pilosol A
Cat.No: TN5811
Synonym:
Target:
Muricarpone B
Cat.No: TN5705
Synonym:
Target:
Karavilagenin F
Cat.No: TN6288
Synonym:
Target:
Epistephamiersine
Cat.No: TN6018
Synonym:
Target:
4',2-Dihydroxy-4,6-dimethoxydihydrochalcone
Cat.No: T39003
Synonym:
Target: Others
Caffeoylcalleryanin
Cat.No: TN7391
Synonym:
Target: Others
15-Dihydroepioxylubimin
Cat.No: TN2637
Synonym:
Target: Others
(+)-D-3-Carene
Cat.No: TN6696
Synonym:
Target:
γ-Asarone
Cat.No: TN5928
Synonym: soasarone,γ-细辛醚
Target:
Isolappaol C
Cat.No: TN6462
Synonym:
Target:
Isomurrayafoline B
Cat.No: TN6158
Synonym:
Target:
Pipoxide chlorohydrin
Cat.No: TN6126
Synonym:
Target:
Betulinic acid palmitate
Cat.No: TN5987
Synonym:
Target:
2',3,5,7-Tetrahydroxyflavone
Cat.No: TN2690
Synonym:
Target: Others
8(14),15-Isopimaradiene-3,18-diol
Cat.No: TN3261
Synonym:
Target: Others
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Cat. No. Product Name Species Expression System
TMPJ-01462 IL-15RA & IL-15 Protein, Human, Recombinant - PBS Lyophilized (hFc)

IL15,IL15RA&IL15,IL-...

Human HEK293 Cells
IL15RA is a high-affinity receptor for interleukin-15. Il15ra associates as a heterotrimer with the IL-2 receptor beta and gamma subunits to initiate signal transduction. It can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. Il15ra is expressed in special cells including a wide variety of Tand B cells and non-lymphoid cells.IL-15 is a cytokine that regulates T cell and natural killer cell activation and proliferation. IL-15 ...
TMPJ-01461 IL-15RA & IL-15 Protein, Human, Recombinant (hFc)

IL-15 Receptor α & IL-15 Fusion Protein,In...

Human HEK293 Cells
IL15RA is a high-affinity receptor for interleukin-15. Il15ra associates as a heterotrimer with the IL-2 receptor beta and gamma subunits to initiate signal transduction. It can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. Il15ra is expressed in special cells including a wide variety of Tand B cells and non-lymphoid cells.IL-15 is a cytokine that regulates T cell and natural killer cell activation and proliferation. IL-15 ...
TMPY-03871 TM4SF2/TSPAN7 Protein, Mouse, Recombinant (His)

AI323365,Tm4sf2,PE31,A15,R74651,T...

Mouse HEK293 Cells
TALLA-1, also known as TSPAN7, is a member of the transmembrane 4 superfamily Most members of this family are cell-surface proteins that are characterized by the presence of four hydrophobic domains. TALLA-1 gene is associated with X-linked mental retardation and neuropsychiatric diseases such as Huntington's chorea, fragile X syndrome and myotonic dystrophy. TALLA-1 is a cell surface glycoprotein and may have a role in the control of neurite outgrowth. It is known to complex with integrins. TM4...
TMPY-03862 TM4SF2/TSPAN7 Protein, Human, Recombinant (His)

TM4SF2,A15,MXS1,tetraspa...

Human HEK293 Cells
TALLA-1, also known as TSPAN7, is a member of the transmembrane 4 superfamily Most members of this family are cell-surface proteins that are characterized by the presence of four hydrophobic domains. TALLA-1 gene is associated with X-linked mental retardation and neuropsychiatric diseases such as Huntington's chorea, fragile X syndrome and myotonic dystrophy. TALLA-1 is a cell surface glycoprotein and may have a role in the control of neurite outgrowth. It is known to complex with integrins. TM4...
TMPY-04325 Influenza A H3N2 (A/Wisconsin/15/2009) Hemagglutinin/HA1 Protein (His)

Harvey rat sarcoma vir

H3N2 HEK293 Cells
Influenza A H3N2 (A/Wisconsin/15/2009) Hemagglutinin/HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38 kDa and the accession number is I6TE52.
TMPY-02001 RTN4 Protein, Human, Recombinant (GST)

UNG1,NOGO,reticulon 4,RTN4-A,Nbla00271,NOG...

Human E. coli
Reticulon-4, also known as Foocen, Neurite outgrowth inhibitor, Nogo protein, Neuroendocrine-specific protein, Neuroendocrine-specific protein C homolog, RTN-x, Reticulon-5 and RTN4, is a multi-pass membrane protein that contains one reticulon domain. Isoform 1 of RTN4 is specifically expressed in brain and testis and weakly in heart and skeletal muscle. Isoform 2 of RTN4 is widely expressed except for the liver. Isoform 3 of RTN4 is expressed in brain, skeletal muscle and adipocytes. Isoform 4 ...
TMPY-05924 Influenza A H1N1 (A/swine/Iowa/15/1930) Neuraminidase/NA Protein (His)

NA Protein

H1N1 HEK293 Cells
Influenza A H1N1 (A/swine/Iowa/15/1930) Neuraminidase/NA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.3 kDa and the accession number is Q9IBI2.
TMPY-03859 DHRS9 Protein, Human, Recombinant (His)

3α-HSD,RDHTBE,3ALPHA-HSD,RDH-E2,RETSDR8,de...

Human E. coli
Dehydrogenase/reductase (SDR family) member 9 (DHRS9) is aberrantly expressed in colorectal cancer (CRC), the decreased expression of DHRS9 correlates with tumor progression and may serve as a potential prognostic biomarker in CRC. The human regulatory macrophage (Mreg) has emerged as a promising cell type for use as a cell-based adjunct immunosuppressive therapy in solid organ transplant recipients. DHRS9 is a specific and stable marker of human Mregs.
TMPJ-01099 IL-15RA Protein, Human, Recombinant (hFc, Human Cells)

interleukin-15 receptor subunit α,IL15R

Human HEK293 Cells
Interleukin 15 Receptor alpha (IL-15Rα) is a transmembrane glycoprotein that plays a pleiotropic role in immune development and function, including the positive maintenance of lymphocyte homeostasis. IL-15Rα chain can bind soluble IL-15 and “transpresent” cytokine to the cells, allowing them to respond to IL-15. Soluble IL-15Rα can function as a specific high-affinity IL-15 antagonist. The soluble IL-15/IL-15Rα complexes exhibit a strong agonistic activity which is mediated through membrane-boun...
TMPK-01243 GDF-15 Protein, Rat, Recombinant (His)

GDF-15,PDF,PTGF-beta,MIC-1,MIC1,GDF15<...

Rat E. coli
Growth Differentiation Factor 15 (GDF15), also known as NSAID activated gene-1 (NAG-1), is associated with a large number of biological processes and diseases, including cancer and obesity. GDF15 is synthesized as pro-GDF15, is dimerized, and is cleaved and secreted into the circulation as a mature dimer GDF15. GDF-15 Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-His tag. The predicted molecular weight is 13.68 kDa and the accession number is Q9Z0J6.
TMPJ-00154 IL-15RA Protein, Mouse, Recombinant (hFc, Human Cells)

sIL-15 receptor subunit α,Il15ra,...

Mouse HEK293 Cells
Mouse interleukin-15 receptor subunit alpha, also known as Il15ra, is a high-affinity receptor for interleukin-15. Il15ra associates as a heterotrimer with the IL-2 receptor beta and gamma subunits (Common gamma chain, or gamma c) to initiate signal transduction. It can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. Il15ra is expressed in special cells including a wide variety of Tand B cells and non-lymphoid cells. Human Il...
TMPK-01246 GDF-15 Protein, Mouse, Recombinant (His)

MIC1,Placental TGF-beta,Pla

Mouse E. coli
Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance. GDF-15 Protein, Mouse, Rec...
TMPK-01150 Beta Klotho Protein, Mouse, Recombinant (His)

Klotho beta,β-klotho,MGC142213,βKlotho,β Klotho,KLB...

Mouse HEK293 Cells
Beta-klotho (KLB) is a coreceptor required for endocrine fibroblast growth factor (FGF) 15/19 and FGF21 signaling in the brain. Klb is prominent within the hypothalamus, which is consistent with its metabolic functions, but diverse roles for Klb are now emerging. Central Klb expression is low but discrete and may govern FGF-targeted sites. Beta Klotho Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 109.91 kDa and the acce...
TMPJ-00603 TL1A/TNFSF15 Protein, Mouse, Recombinant

TNFSF15,Tumor Necrosis Factor Liga

Mouse E. coli
Tumor Necrosis Factor Ligand Superfamily Member 15 (TNFSF15) is a new member of the tumor necrosis factor family. TNFSF15 is predominantly an endothelial cell-specific gene, and recombinant TNFSF15 is a potent inhibitor of endothelial cell proliferation, angiogenesis and tumor growth. TNFSF15 exerts two activities on endothelial cells: early G1 arrest of G0/G1-cells responding to growth stimuli and programmed cell death of proliferating cells. These activities are highly specific to endothelial ...
TMPY-01813 ACRV1 Protein, Human, Recombinant (His)

SP-10,SPACA2,D11S4365,acrosom...

Human HEK293 Cells
Acrosomal protein SP-1, also known as Acrosomal vesicle protein 1 and ACRV1, is a testis-specific, differentiation antigen, that arises within the acrosomal vesicle during spermatogenesis, and is associated with the acrosomal membranes and matrix of mature sperm. Regulation of cell type-specific gene transcription is central to cellular differentiation and development. During spermatogenesis, a number of testis-specific genes are expressed in a precise spatiotemporal order. The longest tr...
TMPY-00803 Fibronectin Protein, Human, Recombinant (aa 607-1265, His)

GFND,LETS,ED-B,fibronectin 1,CIG,GFND2,FNZ,FINC,FN,MSF

Human HEK293 Cells
Fibronectin Protein, Human, Recombinant (aa 607-1265, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 73.2 kDa and the accession number is P02751-15.
TMPK-01296 Siglec-15 Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated

CD33 molecule-like 3,CD33L3,Siglec15,SIGLEC-15<...

Cynomolgus HEK293 Cells
Siglec-15 is a transmembrane glycoprotein in the Siglec family of sialic acid-binding immune regulatory molecules. Mature human Siglec-15 consists of a 244 amino acid extracellular domain (ECD) with two Ig-like domains, a 21 aa transmembrane segment, and a 44 aa cytoplasmic domain. Siglec-15 is a potential therapeutic target for osteoporosis and plays a conserved regulatory role in the immune system of vertebrates. Siglec-15 Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated is expressed...
TMPK-00217 Siglec-15 Protein, Human, Recombinant (His & Avi)

Siglec15,CD33 molecule-like 3,HsT1361,CD33L3,CD33 <...

Human HEK293 Cells
Siglec-15 is a transmembrane glycoprotein in the Siglec family of sialic acid-binding immune regulatory molecules. Mature human Siglec-15 consists of a 244 amino acid extracellular domain (ECD) with two Ig-like domains, a 21 aa transmembrane segment, and a 44 aa cytoplasmic domain. Siglec-15 is a potential therapeutic target for osteoporosis and plays a conserved regulatory role in the immune system of vertebrates..
TMPK-00231 Siglec-15 Protein (Primary Amine Labeling), Mouse, Recombinant (His), Biotinylated

CD33 molecule-like 3,Siglec15,CD33L3,HsT1361,CD33 <...

Mouse HEK293 Cells
Siglec-15 is a transmembrane glycoprotein in the Siglec family of sialic acid-binding immune regulatory molecules. Mature human Siglec-15 consists of a 244 amino acid extracellular domain (ECD) with two Ig-like domains, a 21 aa transmembrane segment, and a 44 aa cytoplasmic domain. Siglec-15 is a potential therapeutic target for osteoporosis and plays a conserved regulatory role in the immune system of vertebrates. Siglec-15 Protein (Primary Amine Labeling), Mouse, Recombinant (His), Biotinylate...
TMPK-00160 IL-15RA Protein, Human, Recombinant (His & Avi), Biotinylated

MGC104179,IL-15 R α,IL-15RA,IL-

Human HEK293 Cells
Interleukin-15 receptor alpha (IL-15R alpha) is a high affinity IL-15 binding protein that is crucial for mediating IL-15 functions such as memory CD8 T cell proliferation and NK, NK/T cell, and intestinal intraepithelial lymphocyte development. IL-15RA Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 21.3 kDa and the accession number is Q13261-1.
TMPK-00159 IL-15RA Protein, Human, Recombinant (His & Avi)

IL-15 R α,IL-15RA/IL-15 ...

Human HEK293 Cells
Interleukin-15 receptor alpha (IL-15R alpha) is a high affinity IL-15 binding protein that is crucial for mediating IL-15 functions such as memory CD8 T cell proliferation and NK, NK/T cell, and intestinal intraepithelial lymphocyte development. IL-15RA Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 21.3 kDa and the accession number is Q13261-1.
TMPK-01295 Siglec-15 Protein, Cynomolgus, Recombinant (His & Avi)

CD33 molecule-like 3,Siglec15,CD33 antigen...

Cynomolgus HEK293 Cells
Siglec-15 is a transmembrane glycoprotein in the Siglec family of sialic acid-binding immune regulatory molecules. Mature human Siglec-15 consists of a 244 amino acid extracellular domain (ECD) with two Ig-like domains, a 21 aa transmembrane segment, and a 44 aa cytoplasmic domain. Siglec-15 is a potential therapeutic target for osteoporosis and plays a conserved regulatory role in the immune system of vertebrates. Siglec-15 Protein, Cynomolgus, Recombinant (His & Avi) is expressed in HEK293 mam...
TMPJ-00565 Mucin-15/MUC15 Protein, Human, Recombinant (His)

MUC15,Mucin-15,MUC-15

Human HEK293 Cells
Mucin-15 is a single-pass type I membrane protein member of the Mucin family. Mucins are a family of high molecular weight, heavily glycosylated proteins (glycoconjugates) produced by epithelial tissues in most metazoans. A key characteristic of Mucins is their ability to form gels. Therefore they are a key component in most gel-like secretions, serving functions from lubrication to cell signalling to forming chemical barriers. Mucin-15 is expressed in many tissues. Mucin-15 is highly glycosylat...
TMPK-00569 GDF-15 Protein, Canine, Recombinant (His)

GDF15,MIC1,MIC-1,PLAB,GDF-15,PDF,...

Canine E. coli
Growth Differentiation Factor 15 (GDF15), also known as NSAID activated gene-1 (NAG-1), is associated with a large number of biological processes and diseases, including cancer and obesity. GDF15 is synthesized as pro-GDF15, is dimerized, and is cleaved and secreted into the circulation as a mature dimer GDF15. GDF-15 Protein, Canine, Recombinant (His) is expressed in E. coli expression system with N-His tag. The predicted molecular weight is 13.12 kDa and the accession number is A0A8C0TNP6.
TMPK-00196 GDF-15 Protein, Human, Recombinant (His & Avi), Biotinylated

NAG-1,Placental TGF-beta...

Human E. coli
Growth Differentiation Factor 15 (GDF15), also known as NSAID activated gene-1 (NAG-1), is associated with a large number of biological processes and diseases, including cancer and obesity. GDF15 is synthesized as pro-GDF15, is dimerized, and is cleaved and secreted into the circulation as a mature dimer GDF15. GDF-15 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in E. coli expression system with N-His-Avi tag. The predicted molecular weight is 15.19 kDa and the accession nu...
TMPJ-01414 GDF-15 Protein, Mouse, Recombinant (His & Flag)

Growth Differentiation Factor 15,...

Mouse HEK293 Cells
Growth Differentiation Factor 15 (GDF-15), also called Macrophage Inhibitory Cytokine 1 (MIC-1), is a divergent member of the TGF-beta superfamily. GDF15 can be secreted by a wide variety of cell types in response to a broad range of stressors. GDF-15 expression is dramatically upregulated during acute brain injury, cancer, cardiovascular disease, and inflammation, suggesting its potential value as a disease biomarker. GDF15 was shown to inhibit proliferation of primitive hematopoietic progenito...
TMPJ-00225 Siglec-15 Protein, Mouse, Recombinant (His)

Siglec-15,Sialic acid-binding Ig-...

Mouse HEK293 Cells
Human Siglec-15 is a transmembrane glycoprotein in the Siglec family. Siglecs are type I transmembrane proteins where the NH3+-terminus is in the extracellular space and the COO−-terminus is cytosolic. Each Siglec contains an N-terminal V-type immunoglobulin domain (Ig domain) which acts as the binding receptor for sialic acid. These lectins are placed into the group of I-type lectins because the lectin domain is an immunoglobulin fold. All Siglecs are extended from the cell surface by C2-type I...
TMPK-01244 GDF-15 Protein, Mouse, Recombinant (hFc)

PTGFBPTGF-beta,PTGFB,PLAB,NAG-1,P...

Mouse HEK293 Cells
Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance. GDF-15 Protein, Mouse, Rec...
TMPK-00664 GDF-15 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (hFc), Biotinylated

Placental TGF-beta,PTGFBPTGF-β,PL...

Cynomolgus HEK293 Cells
Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance. GDF-15 Protein (Primary Am...
TMPK-00198 GDF-15 Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated

MIC-1,PTGFBPTGF-β,GDF15,PTGF-β,GDF-15,PTGF...

Human HEK293 Cells
Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance. GDF-15 Protein (Primary Am...
TMPK-00665 GDF-15 Protein, Cynomolgus, Recombinant (His)

PTGFBPTGF-beta,PTGFBPTGF-β,MIC-1,NAG-1,MIC...

Cynomolgus E. coli
Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance. GDF-15 Protein, Cynomolgus...
TMPK-00663 GDF-15 Protein, Cynomolgus, Recombinant (hFc)

PTGF-β,GDF-15,NAG-1,PTGF-beta,PDF...

Cynomolgus HEK293 Cells
Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance. GDF-15 Protein, Cynomolgus...
TMPH-00618 Exopolyphosphatase Protein, E. coli, Recombinant (His & SUMO)

ppx,Metaphosphatase,Exopolyphosph...

E. coli E. coli
Degradation of inorganic polyphosphates (polyP). Releases orthophosphate processively from the ends of the polyP chain. Has a strong preference for long-chain polyphosphates and has only weak affinity for smaller size polyP of about 15 residues.
TMPK-01245 GDF-15 Protein (Primary Amine Labeling), Mouse, Recombinant (hFc), Biotinylated

RG-1,GDF15,Placental TGF-beta...

Mouse HEK293 Cells
Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance. GDF-15 Protein (Primary Am...
TMPK-00197 GDF-15 Protein (Primary Amine Labeling), Human, Recombinant (H202D, hFc), Biotinylated

Placental TGF-β,GDF15,RG-1,MIC-1,...

Human HEK293 Cells
Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance. GDF-15 Protein (Primary Am...
TMPH-01665 TIMP3 Protein, Human, Recombinant (His)

Tissue inhibitor of metalloproteinases 3,T...

Human E. coli
Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. May form part of a tissue-specific acute response to remodeling stimuli. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-9, MMP-13, MMP-14 and MMP-15.
TMPJ-00087 VMO1 Protein, Human, Recombinant (His)

VMO1,Vitelline Membrane Outer Layer Protei...

Human HEK293 Cells
Vitelline membrane outer layer protein 1 homolog (VMO1) belongs to the VMO1 family is a 202 amino acid secreted protein. Exact function not known, component of the outer membrane of the vitelline layer of the egg. Seems to be able to synthesize N-acetylchito-oligosaccharides (n=14-15) from hexasaccharides of N-acetylglucosamine in a manner similar to the transferase activity of lysozyme.
TMPY-06012 SARS-CoV-2 NSP10 Protein

SARS-CoV-2 E. coli
NSP10 is a major regulator of coronavirus replicase function. NSP10 contains two zinc fingers and binds and stimulates both NSP14 and NSP16 activities. Researchers has found that the nsp10 surface that interacts with nsp14 and nsp16 and possibly other subunits of the viral replication complex may be a target for the development of antiviral compounds against pathogenic coronaviruses. SARS-CoV-2 NSP10 Protein is expressed in E. coli expression system. The predicted molecular weight is 15 kDa and ...
TMPJ-00785 FABP3 Protein, Human, Recombinant (His)

H-FABP,FABP11,Fatty Acid...

Human E. coli
Fatty Acid Binding Protein 3 (FABP3) is a small cytoplasmic protein (15 kDa) that is released from cardiac myocytes following an ischemic episode. Like the nine other distinct FABPs that have been identified, FABP3 is involved in active fatty acid metabolism where it transports fatty acids from the cell membrane to mitochondria for oxidation. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-types. They form 14-15 kDa proteins and are thought to p...
TMPY-01577 ORP150 Protein, Human, Recombinant (His)

hypoxia up-regulated 1,HSP12A,Grp...

Human HEK293 Cells
Hypoxia up-regulated protein 1, also known as 15 kDa oxygen-regulated protein, 17 kDa glucose-regulated protein, ORP-15, GRP-17, and HYOU1, is a member of the heat shock protein 7 family. Seven members from four different heat shock protein (HSP) families were identified including HYOU1 (ORP15), HSPC1 (HSP86), HSPA5 (Bip), HSPD1 (HSP6), and several isoforms of the two testis-specific HSP7 chaperones HSPA2 and HSPA1L. HYOU1 is highly expressed in tissues that contain well-developed endoplasmic re...
TMPK-00143 TL1A/TNFSF15 Trimer Protein, Human, Recombinant (His & Flag)

TL1A,TL1,TNFSF15,VEGI,VEGI192A,VE...

Human HEK293 Cells
TNF superfamily member 15 (TNFSF15), a cytokine largely produced by vascular endothelial cells and a specific inhibitor of the proliferation of these same cells, can inhibit VEGF-induced vascular permeability in vitro and in vivo, and that death receptor 3 (DR3), a cell surface receptor of TNFSF15, mediates TNFSF15-induced dephosphorylation of VEGFR2. TNFSF15 Trimer Protein, Human, Recombinant (His & Flag) is expressed in HEK293 mammalian cells with N-His-Flag tag. The predicted molecular weight...
TMPH-02342 Collagenase Protein, Hypoderma lineatum, Recombinant (His & Myc)

Collagenase,HC,Hypodermin C

Hypoderma lineatum E. coli
This enzyme is a serine protease capable of degrading the native triple helix of collagen. Also cleaves the B chain of insulin at the 15-Leu-|-Try-16 and 22-Arg-|-Gly-23 bonds. Hydrolyzes casein, but not Px-Pro-Leu-Gly-Pro-DArg, BzArgNHPh, AcTyrNHPh, 2-naphthyl phosphate, 2-naphthyl butyrate, 2-naphthyl caprylate, 2-naphthyl myristate, L-leucine 2-2-naphthylamide, L-valine 2-naphthylamide, L-cysteine 2-naphthylamide or L-glutarylphenylalanine 2-naphthylamide.
TMPK-00489 TL1A/TNFSF15 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)

TNFSF15,TNF superfamily member 15...

Cynomolgus,Rhesus HEK293 Cells
TNF superfamily member 15 (TNFSF15), a cytokine largely produced by vascular endothelial cells and a specific inhibitor of the proliferation of these same cells, can inhibit VEGF-induced vascular permeability in vitro and in vivo, and that death receptor 3 (DR3), a cell surface receptor of TNFSF15, mediates TNFSF15-induced dephosphorylation of VEGFR2. TNFSF15 Protein, Cynomolgus/Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weigh...
TMPK-00933 ADAM8/CD156a Protein, Mouse, Recombinant (His)

CD156a,MGC134985,ADAM 8,...

Mouse HEK293 Cells
A Disintegrin And Metalloproteinase (ADAM) proteases constitute a family of multifunctional, membrane-bound proteins with traditional sheddase functions. Their protumorigenic potential has been attributed to both, essential (ADAM10 and ADAM17) and 'dispensable' ADAM proteases (ADAM8, 9, 12, 15, and 19). Of specific interest in this review is the ADAM proteinase ADAM8 that has been identified as a significant player in aggressive malignancies including breast, pancreatic, and brain cancer. ADAM8/...
TMPJ-01394 CXCL15 Protein, Mouse, Recombinant (His)

Lungkine,C-X-C motif chemokine 15,Small-in...

Mouse HEK293 Cells
Mouse C-X-C motif chemokine 15, also known as Cxcl15, is a secreted protein which is member of the ELR motif-containing CXC chemokines. It expressed at low levels in fetal lung, the expression restricted to the lung, produced by bronchoepithelial cells and is released into the airways. It plays an important role in lung-specific neutrophil trafficking during normal and inflammatory conditions. It also appears chemotactic for neutrophils.
TMPJ-01056 IL-18 Protein, Mouse, Recombinant (His)

Interferon γ-inducing factor,Interleukin-1 ga

Mouse E. coli
Interleukin-18 (IL-18)is a protein which belongs to the IL-1 family. It is expressed as a 24 kDa precursor by endothelial and epithelial cells, keratinocytes, gamma δ T cells, and phagocytes. Mature mouse IL-18 shares 63% and 91% amino acid sequence identity with mouse and rat IL-18, respectively. IL-18 binds to the widely expressed IL-18 R alpha which recruits IL-18 R beta to form the signaling receptor complex. Its bioactivity is negatively regulated by interactions with IL-18 binding proteins...
TMPK-01078 Beta Klotho Protein, Human, Recombinant (His)

beta-klotho,MGC142213,betaKlotho,BKL,β-klo...

Human HEK293 Cells
Beta-klotho (KLB) is a coreceptor required for endocrine fibroblast growth factor (FGF) 15/19 and FGF21 signaling in the brain. Klb is prominent within the hypothalamus, which is consistent with its metabolic functions, but diverse roles for Klb are now emerging. Central Klb expression is low but discrete and may govern FGF-targeted sites. Beta Klotho Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 111.6 kDa and the acces...
TMPJ-00832 Granzyme D/GZMD Protein, Mouse, Recombinant (His)

Granzyme D,Gzmd

Mouse HEK293 Cells
Granzyme D is a member of the granzyme family of the serine proteases which plays a role in the induction of apoptosis. T cells, lymphohematopoietic stromal cells, and granulated metrial gland cells express granzyme D, but the function of granzyme D is unknown. Previous studies reported that granzyme D is developmentally regulated during pregnancy together with granzymes E, F, and G in granulated metrial gland cells and is upregulated by IL-2 and IL-15. Granzyme D was also suggested to have a ro...
TMPK-00918 ADAM8/CD156a Protein, Human, Recombinant (aa 17-655, His)

CD156a,ADAM 8,MGC134985,...

Human HEK293 Cells
A Disintegrin And Metalloproteinase (ADAM) proteases constitute a family of multifunctional, membrane-bound proteins with traditional sheddase functions. Their protumorigenic potential has been attributed to both, essential (ADAM10 and ADAM17) and 'dispensable' ADAM proteases (ADAM8, 9, 12, 15, and 19). Of specific interest in this review is the ADAM proteinase ADAM8 that has been identified as a significant player in aggressive malignancies including breast, pancreatic, and brain cancer. ADAM8/...
TMPJ-01125 PEA15 Protein, Human, Recombinant

15 kDa Phosphoprotein Enriched in A

Human E. coli
Astrocyticphosphoprotein PEA-15 (PEA15) is a death effector domain (DED)-containing protein. PEA15 is mainly expressed in the central nervous system, principally in astrocytes. Increased PEA15 levels affect tumorigenesis and cancer progression. PEA15 is overexpressed in breast cancers and gliomas as well as in type 2 diabetes. PEA15 blocks Ras-mediated inhibition of integrin activation and modulates the ERK MAP kinase cascade. PEA15 also inhibits RPS6KA3 activities by holding it in the cytoplasm...
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重组蛋白

IL-15RA & IL-15 Protein, Human, Recombinant - PBS Lyophilized (hFc)
Cat.No: TMPJ-01462
Species: Human
Expression System: HEK293 Cells
IL-15RA & IL-15 Protein, Human, Recombinant (hFc)
Cat.No: TMPJ-01461
Species: Human
Expression System: HEK293 Cells
TM4SF2/TSPAN7 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-03871
Species: Mouse
Expression System: HEK293 Cells
TM4SF2/TSPAN7 Protein, Human, Recombinant (His)
Cat.No: TMPY-03862
Species: Human
Expression System: HEK293 Cells
Influenza A H3N2 (A/Wisconsin/15/2009) Hemagglutinin/HA1 Protein (His)
Cat.No: TMPY-04325
Species: H3N2
Expression System: HEK293 Cells
RTN4 Protein, Human, Recombinant (GST)
Cat.No: TMPY-02001
Species: Human
Expression System: E. coli
Influenza A H1N1 (A/swine/Iowa/15/1930) Neuraminidase/NA Protein (His)
Cat.No: TMPY-05924
Species: H1N1
Expression System: HEK293 Cells
DHRS9 Protein, Human, Recombinant (His)
Cat.No: TMPY-03859
Species: Human
Expression System: E. coli
IL-15RA Protein, Human, Recombinant (hFc, Human Cells)
Cat.No: TMPJ-01099
Species: Human
Expression System: HEK293 Cells
GDF-15 Protein, Rat, Recombinant (His)
Cat.No: TMPK-01243
Species: Rat
Expression System: E. coli
IL-15RA Protein, Mouse, Recombinant (hFc, Human Cells)
Cat.No: TMPJ-00154
Species: Mouse
Expression System: HEK293 Cells
GDF-15 Protein, Mouse, Recombinant (His)
Cat.No: TMPK-01246
Species: Mouse
Expression System: E. coli
Beta Klotho Protein, Mouse, Recombinant (His)
Cat.No: TMPK-01150
Species: Mouse
Expression System: HEK293 Cells
TL1A/TNFSF15 Protein, Mouse, Recombinant
Cat.No: TMPJ-00603
Species: Mouse
Expression System: E. coli
ACRV1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01813
Species: Human
Expression System: HEK293 Cells
Fibronectin Protein, Human, Recombinant (aa 607-1265, His)
Cat.No: TMPY-00803
Species: Human
Expression System: HEK293 Cells
Siglec-15 Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-01296
Species: Cynomolgus
Expression System: HEK293 Cells
Siglec-15 Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00217
Species: Human
Expression System: HEK293 Cells
Siglec-15 Protein (Primary Amine Labeling), Mouse, Recombinant (His), Biotinylated
Cat.No: TMPK-00231
Species: Mouse
Expression System: HEK293 Cells
IL-15RA Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00160
Species: Human
Expression System: HEK293 Cells
IL-15RA Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00159
Species: Human
Expression System: HEK293 Cells
Siglec-15 Protein, Cynomolgus, Recombinant (His & Avi)
Cat.No: TMPK-01295
Species: Cynomolgus
Expression System: HEK293 Cells
Mucin-15/MUC15 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00565
Species: Human
Expression System: HEK293 Cells
GDF-15 Protein, Canine, Recombinant (His)
Cat.No: TMPK-00569
Species: Canine
Expression System: E. coli
GDF-15 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00196
Species: Human
Expression System: E. coli
GDF-15 Protein, Mouse, Recombinant (His & Flag)
Cat.No: TMPJ-01414
Species: Mouse
Expression System: HEK293 Cells
Siglec-15 Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00225
Species: Mouse
Expression System: HEK293 Cells
GDF-15 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPK-01244
Species: Mouse
Expression System: HEK293 Cells
GDF-15 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (hFc), Biotinylated
Cat.No: TMPK-00664
Species: Cynomolgus
Expression System: HEK293 Cells
GDF-15 Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated
Cat.No: TMPK-00198
Species: Human
Expression System: HEK293 Cells
GDF-15 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-00665
Species: Cynomolgus
Expression System: E. coli
GDF-15 Protein, Cynomolgus, Recombinant (hFc)
Cat.No: TMPK-00663
Species: Cynomolgus
Expression System: HEK293 Cells
Exopolyphosphatase Protein, E. coli, Recombinant (His & SUMO)
Cat.No: TMPH-00618
Species: E. coli
Expression System: E. coli
GDF-15 Protein (Primary Amine Labeling), Mouse, Recombinant (hFc), Biotinylated
Cat.No: TMPK-01245
Species: Mouse
Expression System: HEK293 Cells
GDF-15 Protein (Primary Amine Labeling), Human, Recombinant (H202D, hFc), Biotinylated
Cat.No: TMPK-00197
Species: Human
Expression System: HEK293 Cells
TIMP3 Protein, Human, Recombinant (His)
Cat.No: TMPH-01665
Species: Human
Expression System: E. coli
VMO1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00087
Species: Human
Expression System: HEK293 Cells
SARS-CoV-2 NSP10 Protein
Cat.No: TMPY-06012
Species: SARS-CoV-2
Expression System: E. coli
FABP3 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00785
Species: Human
Expression System: E. coli
ORP150 Protein, Human, Recombinant (His)
Cat.No: TMPY-01577
Species: Human
Expression System: HEK293 Cells
TL1A/TNFSF15 Trimer Protein, Human, Recombinant (His & Flag)
Cat.No: TMPK-00143
Species: Human
Expression System: HEK293 Cells
Collagenase Protein, Hypoderma lineatum, Recombinant (His & Myc)
Cat.No: TMPH-02342
Species: Hypoderma lineatum
Expression System: E. coli
TL1A/TNFSF15 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)
Cat.No: TMPK-00489
Species: Cynomolgus,Rhesus
Expression System: HEK293 Cells
ADAM8/CD156a Protein, Mouse, Recombinant (His)
Cat.No: TMPK-00933
Species: Mouse
Expression System: HEK293 Cells
CXCL15 Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-01394
Species: Mouse
Expression System: HEK293 Cells
IL-18 Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-01056
Species: Mouse
Expression System: E. coli
Beta Klotho Protein, Human, Recombinant (His)
Cat.No: TMPK-01078
Species: Human
Expression System: HEK293 Cells
Granzyme D/GZMD Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00832
Species: Mouse
Expression System: HEK293 Cells
ADAM8/CD156a Protein, Human, Recombinant (aa 17-655, His)
Cat.No: TMPK-00918
Species: Human
Expression System: HEK293 Cells
PEA15 Protein, Human, Recombinant
Cat.No: TMPJ-01125
Species: Human
Expression System: E. coli
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Cat. No. Product Name Target Signaling Pathways
TMID-0277 4-AcetaMido-d3-antipyrine

4-AcetaMido-d3-antipyrine 是 4-AcetaMido-antipyrine 的氘代化合物。4-AcetaMido-antipyrine 的 CAS 号为 83-15-8。
TMIH-0441 Piroxicam EP Impurity J-d3

Piroxicam EP Impurity J-d3 是 Piroxicam EP Impurity J 的氘代化合物。Piroxicam EP Impurity J 的 CAS 号为 35511-15-0。
TMIH-0218 Enzalutamide-d6 Carboxylic Acid

Enzalutamide-d6 Carboxylic Acid 是 Enzalutamide Carboxylic Acid 的氘代化合物。Enzalutamide Carboxylic Acid 的 CAS 号为 1242137-15-0。Enzalutamide carboxylic acid 是 Enzalutamide 非活性代谢物。Enzalutamide 是雄激素受体 (AR) 拮抗剂。
TMIJ-0408 1-Naphthol-d8

1-Naphthol-d8 是 1-Naphthol 的氘代化合物。1-Naphthol 的 CAS 号为 90-15-3。1-naphthol 是激发态质子转移荧光分子探针。
T71205 Fosinopril-d7 sodium salt

Fosinopril-d7 is intended for use as an internal standard for the quantification of fosinopril by GC- or LC-MS. Fosinopril is a prodrug form of the angiotensin-converting enzyme inhibitor fosinoprilat. Oral administration of fosinopril inhibits angiotensin I-induced pressor responses in normotensive rats, dogs, and monkeys when administered at doses of 15, 15, and 10 µmol/kg, respectively. Fosinopril reduces fractional shortening and decreases left ventricular size in a porcine model of congesti...
TMIJ-0295 Flubendazole-d3 (methyl-d3)

Flubendazole-d3 (methyl-d3) 是 Flubendazole 的氘代化合物。Flubendazole 的 CAS 号为 31430-15-6。Flubendazole 是用于治疗人类蠕虫感染的驱虫药。它通过抑制微管功能等机制发挥抗癌作用。它诱导p53介导的细胞凋亡,抑制 G2/M 细胞周期。
T13308 Vortioxetine D8

Lu AA 21004 D8

Others Others
Vortioxetine D8 is a deuterium labeled Vortioxetine. Vortioxetine is an 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT inhibitor (Kis: 15 nM, 33 nM, 3.7 nM, 19 nM and 1.6 nM, respectively).
TMID-0029 Succinic-2,2,3,3-d4 Acid

Succinic-2,2,3,3-d4 Acid 是 Succinic Acid 的氘代化合物。Succinic Acid 的 CAS 号为 110-15-6。Succinic acid 是无氧代谢的发酵产物,也是三羧酸循环的中间产物。
T35513 13C15-Nivalenol

13C15-Nivalenol

13C15-Nivalenol is intended for use as an internal standard for the quantification of nivalenol by GC- or LC-MS. Nivalenol is a trichothecene mycotoxin that has been found inFusarium.1It is lethal to mice (LD50= 6.9 mg/kg).2Nivalenol (5, 10, and 15 mg/kg) also induces thymic, splenic, and Peyer's patch cell apoptosis in mice.3 1.Yang, Z., Concannon, J., Ng, K.S., et al.Tetrandrine identified in a small molecule screen to activate mesenchymal stem cells for enhanced immunomodulationSci. Rep.63026...
TMIJ-0090 L-Carnitine-d9

L-Carnitine-d9 是 L-Carnitine 的氘代化合物。L-Carnitine 的 CAS 号为 541-15-1。L-carnitine 是一种人内源性分子,在人体内以蛋氨酸和赖氨酸为底物进行生物合成,并参与脂肪酸代谢。L-Carnitine 将长链脂肪酰辅酶A转运到线粒体。L-Carnitine 能够改善许多先天性代谢错误的代谢失衡。
TMIJ-0448 Glyphosate-13C2-15N

Glyphosate-13C2-15N 是 Glyphosate 的 13C 和 15 N 的标记化合物。Glyphosate 的 CAS 号为 1071-83-6。Glyphosate 是氨基酸甘氨酸的衍生物。它是一种除草剂,靶向并阻断植物合成芳香氨基酸所必需的莽草酸途径。
TMIJ-0135 Abiraterone-d4

Abiraterone-d4 是 Abiraterone 的氘代化合物。Abiraterone 的 CAS 号为 154229-19-3。Abiraterone 是不可逆的CYP17A1抑制剂,具有抗雄激素作用,抑制细胞色素 p450 酶 CYP17 的 17α-羟化酶 (IC50:2.5 nM) 和 17,20-裂合酶 (IC50:15 nM) 活性。
TMIJ-0130 Vortioxetine-d8

Vortioxetine-d8 是 Vortioxetine 的氘代化合物。Vortioxetine 的 CAS 号为 508233-74-7。Vortioxetine 是5-HT1A、5-HT1B、5-HT3A、5-HT7受体和 5-羟色胺转运体抑制剂,Ki值分别为 15、33、3.7、19 和 1.6 nM。它作为抗抑郁药,用于治疗重度抑郁症。
TMIJ-0381 L-Valine-13C5-15N

L-Valine-13C5-15N 是 L-Valine 的 13C 和 15 N 的标记化合物。L-Valine 的 CAS 号为 72-18-4。L-Valine 是蛋白二十种氨基酸中的其中一种。它是必需氨基酸。
TMIJ-0311 Tranexamic Acid-13C2-15N

Tranexamic Acid-13C2-15N 是 Tranexamic Acid 的 13C 和 15 N 的标记化合物。Tranexamic Acid 的 CAS 号为 1197-18-8。Amstat 是一种能阻断纤溶酶的赖氨酸结合位点和弹性蛋白酶来源的纤维蛋白溶酶原片段。
TMIH-0605 Vortioxetine-d8 2HBr

Vortioxetine-d8 2HBr 是 Vortioxetine 2HBr 的氘代化合物。Vortioxetine 2HBr 的 CAS 号为 508233-74-7。Vortioxetine 是5-HT1A、5-HT1B、5-HT3A、5-HT7受体和 5-羟色胺转运体抑制剂,Ki值分别为 15、33、3.7、19 和 1.6 nM。它作为抗抑郁药,用于治疗重度抑郁症。
TMIJ-0010 Semicarbazide-13C-15N2 Hydrochloride

Semicarbazide-13C-15N2 Hydrochloride 是 Semicarbazide Hydrochloride 的 13C 和 15 N 的标记化合物。Semicarbazide Hydrochloride 的 CAS 号为 563-41-7。Semicarbazide hydrochloride 是一种尿素衍生物,能够与细胞中的铜或铁结合,产生抗病毒、抗感染和抗肿瘤作用。
TMIJ-0380 L-Lysine-13C6-15N2 Hydrochloride

L-Lysine-13C6-15N2 Hydrochloride 是 L-Lysine Hydrochloride 的 13C 和 15 N 的标记化合物。L-Lysine Hydrochloride 的 CAS 号为 657-27-2。L-lysine hydrochloride 是一种人类必需氨基酸,能增加钙吸收,减少糖尿病相关疾病和改善肠道健康,可用于疱疹的研究。
TMIJ-0170 Cefdinir-13C-15N2

Cefdinir-13C-15N2 是 Cefdinir 的 13C 和 15 N 的标记化合物。Cefdinir 的 CAS 号为 91832-40-5。Cefdinir是头孢菌素类中的一种半合成广谱抗生素,对几种革兰氏阴性和革兰氏阳性细菌引起的感染有效。它可研究耳,鼻窦,喉咙和皮肤的常见细菌感染。
TMID-0122 Uric acid-13C-15N2

Uric acid-13C-15N2 是 Uric acid 的 13C 和 15 N 的标记化合物。Uric acid 的 CAS 号为 69-93-2。Uric acid 是一种重要的抗氧化剂。Uric acid 能清除活性氧(ROS) ,如单线态氧和过氧亚硝酸盐,抑制脂质过氧化。Uric acid 有助于维持血压的稳定和抗氧化应激。
T35591 Guanfacine-13C,15N3

Guanfacine-13C,15N3

Guanfacine-13C,15N3is intended for us as an internal standard for the quantification of guanfacine by GC- or LC-MS. Guanfacine is an α2-adrenergic receptor (α2-AR) agonist with Kivalues of 93, 1,380, and 3,890 nM for α2A-, α2B-, and α2C-ARs, respectively, in a radioligand binding assay.1It has EC50values of 52, 288, and 602 nM for α2A-, α2B-, and α2C-ARs, respectively, for stimulated [35S]GTPγS binding. It also binds to imidazoline receptor 1 (Ki= 19 nM in a radioligand binding assay).2Guanfacin...
T37847 Zonisamide-13C2,15N

Zonisamide-13C2,15N

Zonisamide-13C2,15N is intended for use as an internal standard for the quantification of zonisamide by GC- or LC-MS. Zonisamide is an antiepileptic agent.1 It selectively inhibits the repeated firing of sodium channels (IC50 = 2 μg/ml) in mouse embryo spinal cord neurons and inhibits spontaneous channel firing when used at concentrations greater than 10 μg/ml.2 In rat cerebral cortex neurons, zonisamide (1-1,000 μM) inhibits T-type calcium channels with a maximum reduction of 60% of the calcium...

同位素标记化合物

4-AcetaMido-d3-antipyrine
Cat.No: TMID-0277
Synonym:
Target:
Piroxicam EP Impurity J-d3
Cat.No: TMIH-0441
Synonym:
Target:
Enzalutamide-d6 Carboxylic Acid
Cat.No: TMIH-0218
Synonym:
Target:
1-Naphthol-d8
Cat.No: TMIJ-0408
Synonym:
Target:
Fosinopril-d7 sodium salt
Cat.No: T71205
Synonym:
Target:
Flubendazole-d3 (methyl-d3)
Cat.No: TMIJ-0295
Synonym:
Target:
Vortioxetine D8
Cat.No: T13308
Synonym: Lu AA 21004 D8
Target: Others
Succinic-2,2,3,3-d4 Acid
Cat.No: TMID-0029
Synonym:
Target:
13C15-Nivalenol
Cat.No: T35513
Synonym: 13C15-Nivalenol
Target:
L-Carnitine-d9
Cat.No: TMIJ-0090
Synonym:
Target:
Glyphosate-13C2-15N
Cat.No: TMIJ-0448
Synonym:
Target:
Abiraterone-d4
Cat.No: TMIJ-0135
Synonym:
Target:
Vortioxetine-d8
Cat.No: TMIJ-0130
Synonym:
Target:
L-Valine-13C5-15N
Cat.No: TMIJ-0381
Synonym:
Target:
Tranexamic Acid-13C2-15N
Cat.No: TMIJ-0311
Synonym:
Target:
Vortioxetine-d8 2HBr
Cat.No: TMIH-0605
Synonym:
Target:
Semicarbazide-13C-15N2 Hydrochloride
Cat.No: TMIJ-0010
Synonym:
Target:
L-Lysine-13C6-15N2 Hydrochloride
Cat.No: TMIJ-0380
Synonym:
Target:
Cefdinir-13C-15N2
Cat.No: TMIJ-0170
Synonym:
Target:
Uric acid-13C-15N2
Cat.No: TMID-0122
Synonym:
Target:
Guanfacine-13C,15N3
Cat.No: T35591
Synonym: Guanfacine-13C,15N3
Target:
Zonisamide-13C2,15N
Cat.No: T37847
Synonym: Zonisamide-13C2,15N
Target:
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