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Search Results for " 6-phosphate "

40

抑制剂 & 化合物

15

天然产物

2

同位素标记化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T37985	D-Fructose-6-phosphate (sodium salt hydrate) D-Fructose-6-phosphate (sodium salt hydrate) (643-13-0 free base)
	D-Fructose-6-phosphate (sodium salt hydrate) 是由磷酸葡萄糖异构酶将 6-磷酸葡萄糖异构化产生的糖酵解途径的糖中间体，可用于研究癌症。
T37986	D-Mannose-6-Phosphate sodium salt hydrate	Others	Others
	D-Mannose-6-Phosphate sodium salt hydrate 是一种多功能单糖，可用于研究代谢、溶酶体传递和癌症。
T36081	Trehalose 6-phosphate (potassium salt hydrate)	Others	Others
	Trehalose is a natural non-reducing disaccharide found in plants, invertebrates, fungi, and bacteria.1,2In addition to roles as an energy source and stress protectant, trehalose can function as a signaling molecule.3,4Trehalose 6-phosphate is an intermediate in the biosynthesis of trehalose. It is generated from UDP-glucose and glucose 6-phosphate by trehalose 6-phosphate synthase (TPS or otsA).5In plants, changes in trehalose 6-phosphate levels positively correlate with diurnal changes in sucro...
T33856	6-Acryloyloxyhexyl phosphate PA21	Others	Others
	6-Acryloyloxyhexyl phosphate (PA21) 是一种新型磷酸盐结合剂，属于铁基试剂，可用于治疗慢性肾脏病中的高磷血症。
T76152	Glucose 6-phosphate isomerase	Others	Others
	Glucose 6-phosphate isomeras (GPI) 葡萄糖 6-磷酸异构酶，即磷酸葡萄糖异构酶/磷酸葡萄糖异构酶 (PGI) 或磷酸己糖异构酶 (PHI)，常用于生化研究。Glucose 6-phosphate isomeras 是一种高度保守的糖酵解酶和二聚酶。Glucose 6-phosphate isomeras 催化葡萄糖-6-磷酸异构成果糖-6-磷酸。
T73896	Glucose-6-phosphate dehydrogenase	Others	Others
	Glucose-6-phosphate dehydrogenase 是戊糖磷酸途径的限速酶。Glucose-6-phosphate dehydrogenase 是抗氧化途径、一氧化氮合酶、NADPH 氧化酶、细胞色素 p450 等系统中 NADPH 的主要来源。Glucose-6-phosphate dehydrogenase 可用于糖尿病、醛固酮诱导的内皮功能障碍和癌症的研究。
T72092	2-Deoxy-D-glucose 6-phosphate disodium	Others	Others
	2-Deoxy-D-glucose 6-phosphate disodium，一种2-Deoxy-D-glucose的衍生物，是通过己糖激酶在哺乳动物细胞中作用于2-DG而生成。该化合物是葡萄糖代谢的竞争性抑制剂，主要通过抑制己糖激酶从而阻碍糖酵解过程。
T73785	D-Fructose-6-phosphate	Others	Others
	D-Fructose 6-phosphate 是存在于唾液中的内源代谢物，可用于研究路易体痴呆。
T20792	W-7 hydrochloride N-(6-氨基己基)-5-氯-1-萘磺胺盐酸盐,W 7 HCl,W7 HCl,W-7 HCl	CaMK; Apoptosis; Myosin; PDE	Apoptosis; Cytoskeletal Signaling; Metabolism; Neuroscience
	W-7 hydrochloride (W-7 HCl) 是一种选择性的钙调蛋白拮抗剂。它抑制Ca2+-钙调蛋白依赖性磷酸二酯酶和肌球蛋白轻链激酶，IC50值分别为 28 μM 和 51 μM。它可诱导细胞凋亡，具有抗癌活性。
T7394	Toceranib Phosphate SU11654 phosphate,PHA 291639 phosphate,托西尼布磷酸盐	VEGFR; Tyrosinase; PDGFR; c-Kit	Angiogenesis; Proteases/Proteasome; Tyrosine Kinase/Adaptors
	Toceranib Phosphate (SU11654 phosphate) 是有效的、具有口服活性的酪氨酸激酶 (RTK) 受体抑制剂，能抑制PDGFR，VEGFR，Kit，抑制 PDGFRβ 和 Flk-1/KDR 的Ki 分别为 5 nM 和 6 nM。它具有抗肿瘤和抗血管生成作用，可用于研究犬肥大细胞肿瘤。
T7400	RRX-001	Apoptosis; Dehydrogenase; Parasite	Apoptosis; Metabolism; Microbiology/Virology
	RRx-001 是一种低氧选择性的表观遗传因子，被用作放射或化疗敏感剂，能诱发凋亡，克服骨髓瘤的耐药性。它是G6PD 的有效抑制剂，具有抗疟、抗癌活性。它是免疫检查点的抑制剂，可下调CD47和SIRP-α。
T13178	Toceranib 托西尼布,PHA 291639E,SU11654	VEGFR; PDGFR; c-Kit	Angiogenesis; Tyrosine Kinase/Adaptors
	Toceranib (PHA 291639E) 是口服具有活力的受体酪氨酸激酶 (RTK) 抑制剂，能有效抑制PDGFR，VEGFR，Kit，抑制 PDGFRβ 和 Flk-1/KDR 的Ki 分别为 5 nM 和 6 nM。它具有抗肿瘤和抗血管生成作用，用于研究犬肥大细胞肿瘤。
T3312	AM-2394 AM2394	Glucokinase	Metabolism
	AM-2394 是新型的 glucokinase 激活剂 (GKA)。它能够激活葡萄糖激酶 (GK)，EC50=60 nM。
T3258	Ponesimod ACT-128800	S1P Receptor; LPL Receptor	GPCR/G Protein
	Ponesimod (ACT-128800) 是一种选择性 S1P1可口服激动剂，在放射性配体结合试验中的 IC50值为 6 nM。它可高效激活 S1P1介导的信号转导，EC50为5.7 nM。它可预防淋巴细胞介导的组织炎症，具有潜在的免疫调节活性。
T12781	RV01	Others	Others
	RV01 是一种新型的白藜芦醇喹啉取代类似物，可抑制 DNA 损伤，降低乙醇诱导的乙醛脱氢酶 (ALDH2) 的 mRNA 表达，具有清除羟自由基的活性。RV01 降低 iNOS 的表达，具有抗神经炎症作用。RV01降低肿瘤坏死因子-a (TNF-a)和白细胞介素-6 (IL-6) mRNA 水平和分泌，抑制lps 诱导的ROS 生成和烟酰胺腺嘌呤二核苷酸磷酸(NADPH)氧化酶活化，降低toll 样受体4 (TLR4)的蛋白表达，抑制lps 诱导的丝裂原活化蛋白激酶(MAPK)和核转录因子-кB (NF-кB)信号通路的激活。
T27344	FMDP	Others	Others
	FMDP is a glucosamine-6-phosphate synthase inhibitor.
T38294	4-Deoxypyridoxine hydrochloride	S1P Receptor	GPCR/G Protein
	4-Deoxypyridoxine hydrochloride 通过抑制 S1P 裂解酶 (SPL) 活性来抑制细胞内 S1P 的降解，与 S1P 一样，减少化学诱导的胰岛素瘤细胞系的细胞凋亡。
T28649	S-4048 S 4048	Others	Others
	S-4048 is a potent inhibitor of glucose-6-phosphate translocase (G6P T1).
T11347	G6PD activator AG1	Others	Others
	G6PD activator AG1 is a glucose-6-phosphate dehydrogenase (G6PD) activator with an EC50 of 3 µΜ.
T27751	KSK-120 KSK120,KSK 120	Others	Others
	KSK-120 is a potent Chlamydia trachomatis inhibitor, it targets the glucose-6-phosphate (G-6P) metabolism pathway of Chlamydia trachomatis.
T37989	D-Sedoheptulose-7-phosphate (barium salt)	Others	Others
	D-Sedoheptulose-7-phosphate is an intermediate in the pentose phosphate pathway. [1] [2] In this pathway, transaldolase catalyzes the transfer of a three carbon dihydroxyacetone moiety from D-sedoheptulose-7-phosphate to glyceraldehyde-3-phosphate to generate D-fructose-6-phosphate . D-Sedoheptulose-7-phosphate is also an intermediate in carbon fixation in photosynthetic organisms, as well as in the biosynthesis of lipopolysaccharide, amino acids, secondary metabolites, and antibiotics. [3]
T37988	D-Ribulose-5-phosphate (sodium salt) Ru5P,D-Ribulose-5-phosphate (sodium salt)	Others	Others
	D-Ribulose-5-phosphate is an intermediate in the pentose phosphate pathway. [1][2] It can be derived from 6-phosphogluconate by a dehydrogenase or from xylulose 5-phosphate by ribulose phosphate 3-epimerase. D-Ribulose-5-phosphate is also an intermediate in carbon fixation in photosynthetic organisms as well as in the biosynthesis of lipopolysaccharide, amino acids, secondary metabolites, and antibiotics.[3]
T61784	GlcN-6-P Synthase-IN-1	Others	Others
	GlcN-6-P Synthase-IN-1 (Compound 4d) is a potent inhibitor of Glucosamine-6-phosphate (GlcN-6-P) synthase, with an IC50 of 3.47 μM. This compound demonstrates remarkable antimicrobial activity and exhibits excellent penetration in the central nervous system. Additionally, GlcN-6-P Synthase-IN-1 is capable of inhibiting cytochrome P450, specifically the CYP3A4 isoform [1].
T20256	Sorbitol, L- L-Glucitol	Others	Others
	Sorbitol, L- is a sugar alcohol. It can be obtained by the reduction of glucose, which changes the aldehyde group to a hydroxyl group. It is converted to fructose by sorbitol-6-phosphate 2-dehydrogenase. Sorbitol is an isomer of mannitol, another sugar al
T74160	UDP-glucosamine disodium	Others	Others
	UDP-glucosamine (UDP-GlcNAc) disodium 是一种化合物，作为O-GlcNAc转移酶的底物，负责催化O-GlcNAc与蛋白质的结合。同时，O-GlcNAc酶则负责催化从蛋白质中移除O-GlcNAc。作为己糖胺生物合成途径的终产物，UDP-glucosamine (UDP-GlcNAc) disodium主要受葡萄糖-6-磷酸-谷氨酰胺:果糖-6-磷酸氨基转移酶(GFAT)的调节。
T27131	DCG04 DCG-04,CD-892,CD 892,DCG 04,CD892	Others	Others
	DCG04 is a multivalent ligand for the mannose-6-phosphate receptor. DCG-04 is an activity-based probe for cysteine cathepsins, enabled fluorescent readout of its receptor-targeting properties. DCG04 is used for endolysosomal targeting of an activity-based
T79928	Phosphomannose isomerase	Others	Others
	Phosphomannose isomerase 是 GDP-Man 生物合成途径中关键的首要酶，负责催化 Fru6P 与 Man6P 之间的互转。该酶对于细胞壁合成及蛋白质糖基化过程至关重要。同时，作为一种潜在的抗真菌靶点，Phosphomannose isomerase 可以有效抑制 A. flavus。
T35683	2-deoxy-D-Glucose-13C6 2-deoxy-D-Glucose-13C6	Others	Others
	2-deoxy-D-Glucose-13C6is intended for use as an internal standard for the quantification of 2-deoxy-D-glucose by GC- or LC-MS. 2-deoxy-D-Glucose is a glucose antimetabolite and an inhibitor of glycolysis.1,2It inhibits hexokinase, the enzyme that converts glucose to glucose-6-phosphate, as well as phosphoglucose isomerase, the enzyme that converts glucose-6-phosphate to fructose-6-phosphate.32-deoxy-D-Glucose (16 mM) induces apoptosis in SK-BR-3 cells, as well as inhibits the growth of 143B oste...
T35416	α-D-Glucose-1-phosphate (sodium salt hydrate)	Others	Others
	α-D-Glucose-1-phosphate is an intermediate in glycogen metabolism.1,2It is a precursor in the biosynthesis of UDP-glucose, the glucose donor in glycogen biosynthesis.2α-D-Glucose-1-phosphate can be formed during glycogen breakdownviaphosphorolytic cleavage of glycogen by glycogen phosphorylase.1It can be converted to glucose-6-phosphate by phosphoglucomutase. α-D-Glucose-1-phosphate is combined with CTP by α-D-glucose-1-phosphate cytidylyltransferase to form CDP-glucose in the first step of CDP-...
T74034	6-Me-ATP trisodium	Others	Others
	6-Me-ATP trisodium (N6-Methyl-ATP) 是N6-修饰的ATP衍生物，展现对GSK3良好的结合亲和力，可作为GSK3β磷酸化底物肽的磷酸基团供体。
T74033	6-Me-ATP	Others	Others
	6-Me-ATP（N6-Methyl-ATP）为ATP的N6修饰衍生物。该化合物与GSK3β结合亲和力显著，能有效作为GSK3β催化底物肽磷酸化的磷酸基团供体。
T63737	Purine phosphoribosyltransferase-IN-1	Others	Others
	Purinephosphoribosyltransferase-IN-1 (Compound (S,R)-48) 是一种有效的恶性疟原虫 (Pf)、间日疟原虫 (Pv) 和布氏锥虫 (Tbr) 6-氧嘌呤磷酸核糖基转移酶 (PRT) 抑制剂，他们的 Ki 值分别为 50、20 和 2 nM。
T61335	Rucaparib hydrochloride	Others	Others
	Rucaparib hydrochloride, also known as AG014699, is a powerful and orally active compound that inhibits PARP proteins including PARP-1, PARP-2, and PARP-3 with a Ki value of 1.4 nM for PARP1. Additionally, Rucaparib hydrochloride acts as a modest inhibitor of hexose-6-phosphate dehydrogenase (H6PD). This compound shows potential in research for castration-resistant prostate cancer (CRPC) [1] [2] [3] [4].
T61657	Rucaparib acetate	Others	Others
	Rucaparib (AG014699) acetate is a highly effective oral inhibitor of PARP proteins, specifically targeting PARP-1, PARP-2, and PARP-3, with a Ki value of 1.4 nM for PARP1. Additionally, it exhibits inhibitory action on hexose-6-phosphate dehydrogenase (H6PD) to a moderate extent. Rucaparib acetate shows promise in the field of research for castration-resistant prostate cancer (CRPC). [1] [2] [3] [4]
T38336	W140 (trifluoroacetate salt) W140 (trifluoroacetate salt)	Others	Others
	Sphingosine-1-phosphate (S1P) is a bioactive lipid that exhibits a broad spectrum of biological activities including cell proliferation, survival, migration, cytoskeletal organization, and morphogenesis. It exerts its activity by binding to five distinct G protein-coupled receptors, S1P1/EDG-1, S1P2/EDG-5, S1P3/EDG-3, S1P4/EDG-6, and S1P5/EDG-8. W140 is an inactive enantiomer of W146, a selective S1P1 antagonist (Ki = 77 nM), that binds to the S1P1 receptor with a Ki of 4.6 μM (2a = W146; 2b = W...
T85300	Palmitoleic Acid sodium C16:1(9Z),cis-Palmitoleic Acid,(9Z)-Hexadecenoic Acid,C16:1 n-7	Others	Others
	Palmitoleic acid, an ω-7 monounsaturated fatty acid found in macadamia and sea buckthorn oils, enhances both basal and insulin-stimulated glucose uptake, as well as Glut4 protein levels in 3T3-L1 adipocytes at a 200 µM concentration. Ex vivo, at a dosage of 300 mg/kg per day, it significantly increases glucose uptake and both aerobic and anaerobic glycolysis, while decreasing de novo fatty acid synthesis and the activity of lipogenic enzymes, specifically ATP citrate lyase (ACL) and glucose-6-ph...
T77131	Clervonafusp alfa
	Clervonafusp alfa (VAL-1221) 作为一种融合蛋白，针对胞浆及溶酶体糖原进行靶向。该化合物结合了穿透细胞的抗体Fab部分与重组人酸性葡萄糖苷酶 (rhGAA)，通过核苷转运体ENT-2进入细胞质，再利用甘露糖-6-磷酸受体(M6PRs)导向溶酶体。主要应用于晚发型庞贝病的研究领域。
T83827	Adenosine-5'-O-(3-thiotriphosphate) sodium ATPγS,Adenosine 5'-(γ-thio)-triphosphate	Others	Others
	Adenosine-5'-O-(3-thiotriphosphate)（ATPγS）是一种purinergic P2Y11受体的激动剂。在表达人类或犬类P2Y11受体的CHO-K1细胞中，能够诱导肌醇磷酸累积（EC50s分别为1.2和19.3 µM）。ATPγS（10 µM）能抑制Junin病毒导致的编码骨形态生成蛋白6（BMP6）的mRNA水平增加，并减少Junin病毒感染的初代大鼠成骨细胞中的粒子形成单位（PFUs）。使用25 µM浓度时，可以诱导MIN6胰岛β细胞分泌胰岛素。
T65387	Paromomycin, sulfate (1:1)	Others	Others
	Paromomycin (Sulfate Salt) is an aminoglycoside that is active against Gram-negative and many Gram-positive bacteria as well as some protozoa and cestodes. Paromomycin in combination with sodium stibogluconate has proven to be effective in African and Indian VL (visceral leishmaniasis) and improves survival in African VL[3]. PS (Paromomycin Sulfate) is effective for elimination of B. coli without hematological side effects[4]. The activity of phosphoglucose isomerase was slightly inhibited by 10...
T36057	Diallyl Tetrasulfide ICD-1585	Others	Others
	Diallyl tetrasulfide is an organosulfur compound that has been found in A. sativum and has diverse biological activities, including antimicrobial, antioxidant, and anticancer properties.[1],[2],[3],[4] It is active against the bacteria S. aureus and methicillin-resistant S. aureus (MRSA; MICs = 0.5 and 2 mg/L, respectively), as well as the fungi C. albicans, C. krusei, C. glabrata, A. niger, A. flavus, and A. fumigatus (MICs = 0.5, 4, 2, 1, 2, and 4 mg/L, respectively).[1] It reduces cadmium-ind...

化合物

D-Fructose-6-phosphate (sodium salt hydrate)

Cat.No: T37985

Synonym: D-Fructose-6-phosphate (sodium salt hydrate) (643-13-0 free base)

D-Mannose-6-Phosphate sodium salt hydrate

Cat.No: T37986

Target: Others

Trehalose 6-phosphate (potassium salt hydrate)

Cat.No: T36081

Target: Others

6-Acryloyloxyhexyl phosphate

Cat.No: T33856

Synonym: PA21

Target: Others

Glucose 6-phosphate isomerase

Cat.No: T76152

Target: Others

Glucose-6-phosphate dehydrogenase

Cat.No: T73896

Target: Others

2-Deoxy-D-glucose 6-phosphate disodium

Cat.No: T72092

Target: Others

D-Fructose-6-phosphate

Cat.No: T73785

Target: Others

W-7 hydrochloride

Cat.No: T20792

Synonym: N-(6-氨基己基)-5-氯-1-萘磺胺盐酸盐,W 7 HCl,W7 HCl,W-7 HCl

Target: CaMK, Apoptosis, Myosin, PDE

Toceranib Phosphate

Cat.No: T7394

Synonym: SU11654 phosphate,PHA 291639 phosphate,托西尼布磷酸盐

Target: VEGFR, Tyrosinase, PDGFR, c-Kit

Cat.No: T7400

Target: Apoptosis, Dehydrogenase, Parasite

Cat.No: T13178

Synonym: 托西尼布,PHA 291639E,SU11654

Target: VEGFR, PDGFR, c-Kit

Cat.No: T3312

Synonym: AM2394

Target: Glucokinase

Cat.No: T3258

Synonym: ACT-128800

Target: S1P Receptor, LPL Receptor

Cat.No: T12781

Target: Others

Cat.No: T27344

Target: Others

4-Deoxypyridoxine hydrochloride

Cat.No: T38294

Target: S1P Receptor

Cat.No: T28649

Synonym: S 4048

Target: Others

G6PD activator AG1

Cat.No: T11347

Target: Others

Cat.No: T27751

Synonym: KSK120,KSK 120

Target: Others

D-Sedoheptulose-7-phosphate (barium salt)

Cat.No: T37989

Target: Others

D-Ribulose-5-phosphate (sodium salt)

Cat.No: T37988

Synonym: Ru5P,D-Ribulose-5-phosphate (sodium salt)

Target: Others

GlcN-6-P Synthase-IN-1

Cat.No: T61784

Target: Others

Cat.No: T20256

Synonym: L-Glucitol

Target: Others

UDP-glucosamine disodium

Cat.No: T74160

Target: Others

Cat.No: T27131

Synonym: DCG-04,CD-892,CD 892,DCG 04,CD892

Target: Others

Phosphomannose isomerase

Cat.No: T79928

Target: Others

2-deoxy-D-Glucose-13C6

Cat.No: T35683

Synonym: 2-deoxy-D-Glucose-13C6

Target: Others

α-D-Glucose-1-phosphate (sodium salt hydrate)

Cat.No: T35416

Target: Others

6-Me-ATP trisodium

Cat.No: T74034

Target: Others

Cat.No: T74033

Target: Others

Purine phosphoribosyltransferase-IN-1

Cat.No: T63737

Target: Others

Rucaparib hydrochloride

Cat.No: T61335

Target: Others

Rucaparib acetate

Cat.No: T61657

Target: Others

W140 (trifluoroacetate salt)

Cat.No: T38336

Synonym: W140 (trifluoroacetate salt)

Target: Others

Palmitoleic Acid sodium

Cat.No: T85300

Synonym: C16:1(9Z),cis-Palmitoleic Acid,(9Z)-Hexadecenoic Acid,C16:1 n-7

Target: Others

Clervonafusp alfa

Cat.No: T77131

Adenosine-5'-O-(3-thiotriphosphate) sodium

Cat.No: T83827

Synonym: ATPγS,Adenosine 5'-(γ-thio)-triphosphate

Target: Others

Paromomycin, sulfate (1:1)

Cat.No: T65387

Target: Others

Diallyl Tetrasulfide

Cat.No: T36057

Synonym: ICD-1585

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T19262	D-Glucose 6-phosphate disodium salt D-Glucose 6-phosphate disodium salt	Endogenous Metabolite	Metabolism
	D-Glucose 6-phosphate disodium salt 广泛存在于生物提内的化合物，是葡萄糖第 6 号碳经过磷酸化后生成的分子，参与磷酸戊糖途径与糖酵解途径等体内多种多种代谢调节途径。
T4726	D-Glucose 6-phosphate sodium G6P sodium salt,D-Glucose 6-phosphate sodium salt,D-葡萄糖-6-磷酸钠盐,Sodium Glucose-6-Phosphate	Others; Endogenous Metabolite	Metabolism; Others
	D-Glucose 6-phosphate sodium (G6P sodium salt) 是内源性代谢产物的一种。
T4941	D-Fructose-6-phosphate disodium salt D-FRUCTOSE 6-PHOSPHATE DISODIUM SALT,D-果糖-6-磷酸二钠	Others; Endogenous Metabolite	Metabolism; Others
	D-Fructose-6-phosphate disodium salt (D-FRUCTOSE 6-PHOSPHATE DISODIUM SALT) 是内源性代谢产物的一种。
T5069	D-Glucose 6-phosphate potassium salt	Others	Others
	在细胞中，当葡萄糖被己糖激酶或葡萄糖激酶磷酸化或在糖原分解过程中通过磷酸葡萄糖变位酶转化葡萄糖 1-磷酸时，会产生D-glucose 6-phosphate (G6P)。 G6P 位于糖酵解和戊糖磷酸途径的起点。当血糖水平高时，它也可以作为糖原储存。
T78485	D-Glucosamine 6-phosphate Glucosamine-6-phosphate	Endogenous Metabolite	Metabolism
	D-Glucosamine 6-phosphate为内源性代谢分子，谷氨酰胺果糖-6-磷酸氨基转移酶(GFAT)介导合成。该化合物常用于糖尿病研究领域。
T19263	D-Glucose 6-phosphate	Others	Others
	D-glucose 6-phosphate is glucose that is phosphorylated on the carbon 6 hydroxyl group.
T78471	α,α-Trehalose 6-phosphate potassium Tre6P potassium	Endogenous Metabolite	Metabolism
	α,α-Trehalose 6-phosphate (Tre6P) potassium 是一种α,α′-trehalose的6-磷酸衍生物及内源代谢物。在Tre6P磷酸酶 (T6PP) 的催化下，α,α-Trehalose 6-phosphate可被高效转化为α,α′-trehalose。
T10185	6-Phosphogluconic acid	Others; Endogenous Metabolite	Metabolism; Others
	6-Phosphogluconic acid 是竞争性的磷酸葡萄糖异构酶抑制剂，对6-磷酸果糖和6-磷酸葡萄糖和的 Ki 分别为 42 μM 和 48 μM。它属于人内源性代谢物。
T4924	α-D-Glucose-1-phosphate disodium A-D-葡萄糖-1-磷酸-二钠盐,α-D-Glucose 1-phosphate disodium salt hy,α-D-Glucopyranose 1-phosphate	Others; Endogenous Metabolite	Metabolism; Others
	α-D-Glucose 1-phosphate disodium salt hydrate 是合成葡萄糖醛酸的起始原料。它可用作心脏病研究所必需的细胞抑制剂、抗生素、免疫抑制剂和循环系统研究材料。
T8282	(S)-(-)-Perillyl alcohol	Apoptosis; Ras	Apoptosis; GPCR/G Protein; MAPK
	(S)-(-)-Perillyl alcohol (Perillyl alcohol) 是一种在矮松菊中提取的单萜，具有抗癌活性和神经保护活性，可抑制 Ras 的法尼基化，上调 6-磷酸甘露糖受体并诱导细胞凋亡。
T16527	Phytic acid dodecasodium salt hydrate 植酸十二钠盐,myo-Inositol, hexakis(dihydrogen phosphate) dodecasodium salt hydrate,Inositol hexaphosphate dodecasodium salt hydrate	Others; Xanthine Oxidase; Endogenous Metabolite	Metabolism; Others
	Phytic acid dodecasodium salt hydrate (myo-Inositol, hexakis(dihydrogen phosphate) dodecasodium salt hydrate) 是种子和谷物的磷储存化合物。 Phytic acid dodecasodium salt hydrate 抑制酶促超氧化物源黄嘌呤氧化酶，IC50 为 6 mM，并具有抗氧化、神经保护和抗炎作用。
T37984	Fosfructose, sodium salt, hydrate (1:3:8) D-Fructose-1,6-bisphosphate , sodium salt, hydrate (1:3:8)	Others	Others
	D-Fructose-1,6-bisphosphate sodium salt hydrate 是碳水化合物代谢的中间体，包括糖酵解和糖异生。在糖酵解过程中，它是由磷酸果糖激酶磷酸化果糖-6-磷酸产生的。由果糖-1,6-二磷酸酶-1介导的逆反应是糖异生的限速步骤之一。同样的反应也发生在植物的叶绿体中，D-Fructose-1,6-bisphosphate sodium salt hydrate 作为还原性戊糖磷酸循环的一部分。由于癌细胞采用糖酵解作为代谢能量产生的主要来源，这一途径已成为癌症化疗的主要靶点。
TN2749	(2-Aminoethyl)phosphinic acid	Others	Others
	The specific growth rates of C. raciborskii cells in media treated with β-glycerol phosphate, d-glucose-6-phosphate, and (2-aminoethyl)phosphinic acid are significantly higher than those of cells grown in phosphorus free media.
TQ0148	Orotidine 6-Carboxyuridine,Uridin-6-carboxylic acid	Endogenous Metabolite	Metabolism
	Orotidine (Uridin-6-carboxylic acid) 是一种存在于细菌、真菌和植物中的核苷。在人类中，乳清苷以其 5'-磷酸(乳清酸)形式存在。
T35415	α-D-Glucose-1,6-bisphosphate (potassium salt hydrate)	Others	Others
	α-D-Glucose-1,6-bisphosphate is abis-phosphorylated derivative of α-D-glucose that has roles in carbohydrate metabolism.1It is the product of the reaction of glucose-1- or 6-phosphate with glucose-1,6-bisphosphate synthase (PGM2LI) in the conversion of 1,3-bisphosphoglycerate to 3-phosphoglycerate.2It is also a cofactor for the bacterial enzyme phosphopentomutase.3,4α-D-Glucose-1,6-bisphosphate has been used in the study of carbohydrate metabolism. 1.Beitner, R.Regulation of carbohydrate metabol...

天然产物

D-Glucose 6-phosphate disodium salt

Cat.No: T19262

Synonym: D-Glucose 6-phosphate disodium salt

Target: Endogenous Metabolite

D-Glucose 6-phosphate sodium

Cat.No: T4726

Synonym: G6P sodium salt,D-Glucose 6-phosphate sodium salt,D-葡萄糖-6-磷酸钠盐,Sodium Glucose-6-Phosphate

Target: Others, Endogenous Metabolite

D-Fructose-6-phosphate disodium salt

Cat.No: T4941

Synonym: D-FRUCTOSE 6-PHOSPHATE DISODIUM SALT,D-果糖-6-磷酸二钠

Target: Others, Endogenous Metabolite

D-Glucose 6-phosphate potassium salt

Cat.No: T5069

Target: Others

D-Glucosamine 6-phosphate

Cat.No: T78485

Synonym: Glucosamine-6-phosphate

Target: Endogenous Metabolite

D-Glucose 6-phosphate

Cat.No: T19263

Target: Others

α,α-Trehalose 6-phosphate potassium

Cat.No: T78471

Synonym: Tre6P potassium

Target: Endogenous Metabolite

6-Phosphogluconic acid

Cat.No: T10185

Target: Others, Endogenous Metabolite

α-D-Glucose-1-phosphate disodium

Cat.No: T4924

Synonym: A-D-葡萄糖-1-磷酸-二钠盐,α-D-Glucose 1-phosphate disodium salt hy,α-D-Glucopyranose 1-phosphate

Target: Others, Endogenous Metabolite

(S)-(-)-Perillyl alcohol

Cat.No: T8282

Target: Apoptosis, Ras

Phytic acid dodecasodium salt hydrate

Cat.No: T16527

Synonym: 植酸十二钠盐,myo-Inositol, hexakis(dihydrogen phosphate) dodecasodium salt hydrate,Inositol hexaphosphate dodecasodium salt hydrate

Target: Others, Xanthine Oxidase, Endogenous Metabolite

Fosfructose, sodium salt, hydrate (1:3:8)

Cat.No: T37984

Synonym: D-Fructose-1,6-bisphosphate , sodium salt, hydrate (1:3:8)

Target: Others

(2-Aminoethyl)phosphinic acid

Cat.No: TN2749

Target: Others

Cat.No: TQ0148

Synonym: 6-Carboxyuridine,Uridin-6-carboxylic acid

Target: Endogenous Metabolite

α-D-Glucose-1,6-bisphosphate (potassium salt hydrate)

Cat.No: T35415

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
TMIJ-0399	Triphenyl-d15 Phosphate
	Triphenyl-d15 Phosphate 是 Triphenyl Phosphate 的氘代化合物。Triphenyl Phosphate 的 CAS 号为 115-86-6。
T37119	1,2,3-Trioctanoyl-rac-glycerol-13C3 1,2,3-Trioctanoyl-rac-glycerol-13C3
	1,2,3-Trioctanoyl-rac-glycerol-13C3 is intended for use as an internal standard for the quantification of 1,2,3-trioctanoyl-rac-glycerol by GC- or LC-MS. 1,2,3-Trioctanoyl-rac-glycerol is a triacylglycerol that contains octanoic acid at the sn-1, sn-2, and sn-3 positions. Dietary administration of 1,2,3-trioctanoyl-rac-glycerol increases hippocampal levels of the glycolytic metabolites glucose 6-phosphate, fructose 6-phosphate, and β-hydroxybutyrate and the seizure threshold in the 6 Hz psychomo...

同位素标记化合物

Triphenyl-d15 Phosphate

Cat.No: TMIJ-0399

1,2,3-Trioctanoyl-rac-glycerol-13C3

Cat.No: T37119

Synonym: 1,2,3-Trioctanoyl-rac-glycerol-13C3

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