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Search Results for " 5-ht1b "

Targets Recommended: Dopamine Receptor 5-HT Receptor

75

抑制剂 & 化合物

8

重组蛋白

4

同位素标记化合物

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Cat. No.	Product Name	Target	Signaling Pathways
TQ0311	GSK163090	Dopamine Receptor; 5-HT Receptor	GPCR/G Protein; Neuroscience
	GSK163090 是选择性和具有口服活性的5-HT1A/1B/1D 受体拮抗剂，pKi 值分别为 9.4、8.5 和 9.7。它抑制血清素再摄取转运蛋白的功能活性，pKi 值为 6.1，具有抗抑郁和抗焦虑活性。
T8593	RU 24969 free base 5-methoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole	5-HT Receptor	GPCR/G Protein; Neuroscience
	RU 24969 (5-methoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole) 是 5-HT1A 和 5-HT1B 受体的选择性激动剂，Ki 值分别为 0.38 和 2.5 nM。它可减少液体消耗并增加向前运动。
T4560	Alprenolol Alpheprol,阿普洛尔,(RS)-Alprenolol,dl-Alprenolol	5-HT Receptor; Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Alprenolol (Alpheprol) 是一种非选择性β受体阻滞剂，也是5-HT1A 受体拮抗剂。
T22236	Alprenolol hydrochloride 阿普洛尔盐酸盐,盐酸阿普洛尔	5-HT Receptor	GPCR/G Protein; Neuroscience
	Alprenolol hydrochloride 是一种非选择性β受体阻滞剂，也是5-HT1A 受体拮抗剂。
T8737	GR 125743	5-HT Receptor	GPCR/G Protein; Neuroscience
	GR 125743 是选择性的5-HT1B/1D 受体拮抗剂，与野生型的人 h5-HT1B 和 5-HT1D 结合的pKi 分别为 8.85 和 8.31，可用于帕金森病和心血管疾病的研究。
T0203	Sumatriptan succinate 舒马普坦琥珀酸盐,GR 43175,琥珀酸舒马曲坦	5-HT Receptor	GPCR/G Protein; Neuroscience
	Sumatriptan succinate (GR 43175) 是一种5-HT1受体激动剂，可作用于偏头疼的急性治疗。
T11326	Frovatriptan succinate hydrate Frovelan,夫罗曲坦琥珀酸盐水合物 ,Frova	5-HT Receptor	GPCR/G Protein; Neuroscience
	Frovatriptan succinate hydrate (Frova) 是一种有效、高亲和力、选择性和口服活性的 5-HT1B、HT1D 受体激动剂和中等有效的 5-HT7 受体激动剂，pKi 值分别为 8.6、8.4 和 6.7。它可有效治疗各种偏头痛，包括恶心、呕吐、畏光和畏声等相关症状。
T7498	Eltoprazine hydrochloride 1-(2,3-二氢苯并[B][1,4]二氧杂芑-5-基)哌嗪,DU 28853 hydrochloride	5-HT Receptor	GPCR/G Protein; Neuroscience
	Eltoprazine hydrochloride (DU 28853 hydrochloride) 是5-HT1A 和5-HT1B 受体激动剂，也是5-HT2C 受体拮抗剂，pEC50分别为9.96、7.19和6.81。
T11075	Donitriptan	5-HT Receptor	GPCR/G Protein; Neuroscience
	Donitriptan 是一种 5-HT 受体激动剂，对 5-HT1B 和 5-HT1D 的 pKi 分别为 9.4 和 9.3。
T12861	SB-277011 SB-277011A	Dopamine Receptor	GPCR/G Protein; Neuroscience
	SB-277011 (SB-277011A) 是多巴胺 D3 受体的特异性拮抗剂，对 D3 受体、D2 受体、5-HT1D 和 5-HT1B 的 pKi 值分别为 8.0、6.0、5.0 和 <5.2。
T15414	GR 113808 GR-113808	5-HT Receptor	GPCR/G Protein; Neuroscience
	GR 113808 是一种具有选择性的 5-HT4 receptor 拮抗剂，抑制 5-HT1B，5-HT2A，5-HT2C 和 5-HT3 受体，可减弱多巴胺释放。
T12841	SB-224289 hydrochloride SB-224289A	5-HT Receptor	GPCR/G Protein; Neuroscience
	SB-224289 hydrochloride (SB-224289A) 是一种选择性的 5-HT1B receptor 拮抗剂，具有抗焦虑作用。
T6423	BRL-15572 dihydrochloride 四氢罂粟碱盐酸盐,BRL 15573 dihydrochloride	5-HT Receptor	GPCR/G Protein; Neuroscience
	BRL-15572 dihydrochloride (BRL 15573 dihydrochloride) 是一种 5-HT1D 受体拮抗剂，pKi 为 7.9，对 5-HT1A 和 5-HT2B 受体也显示出相当大的亲和力，其选择性是 5-HT1B 受体的 60 倍。
T22576	Anpirtoline hydrochloride D-16949 hydrochloride	5-HT Receptor	GPCR/G Protein; Neuroscience
	Anpirtoline hydrochloride (D-16949 hydrochloride) 是一种新型高效的 5-HT1B 受体激动剂和 5-HT3 受体拮抗剂，具有抗伤害、镇痛和抗抑郁活性，可用于研究运动障碍。
T50039	3-(2-aminopropyl)phenol hydrochloride	Others	Others
	3-(2-aminopropyl)phenol hydrochloride 是一种用作分子结构单元的苯乙胺类化合物。它是一种精神活性药物，是5-HT1A、5-HT1B 和5-HT2C 等几种血清素受体的部分激动剂，也是5-HT2A 受体的拮抗剂。
T22808	GR 46611 3-[3-[2-二甲基氨基乙基]-1H-吲哚-5-基]-N-[4-甲氧基苄基]丙烯酰胺	5-HT Receptor	GPCR/G Protein; Neuroscience
	GR 46611 是一种选择性 5-HT1B 和 5-HT1D 受体激动剂，可用于治疗癫痫的研究。
T12847	SB-616234-A SB-616234A	5-HT Receptor	GPCR/G Protein; Neuroscience
	SB-616234-A 是选择性的，口服有效的5-HT1B receptor 拮抗剂。SB-616234-A 具有抗焦虑和抗抑郁活性。
T21666	Donitriptan hydrochloride 盐酸多尼普曲坦,Donitriptan HCl,Donitriptan monohydrochloride	5-HT Receptor	GPCR/G Protein; Neuroscience
	Donitriptan hydrochloride (Donitriptan monohydrochloride) 是一种有效的高亲和力 5-HT1B/1D 受体激动剂，pKi 分别为 9.4 和 9.3。
T22689	CP94253 hydrochloride CP 94253 hydrochloride	Others; 5-HT Receptor	GPCR/G Protein; Neuroscience; Others
	CP94253 hydrochloride (CP 94253 hydrochloride) 是一种有效的、特异性的和中枢活性的 5-HT1B 受体激动剂，Ki 为 2 nM。5-HT1A、5-HT1D、5-HT1C 和 5-HT2 的 Ki 分别为 89、49、860 和 1600 nM 。
T21231	Almotriptan 阿莫曲坦,LAS 31416,阿莫曲普坦	5-HT Receptor	GPCR/G Protein; Neuroscience
	Almotriptan (LAS 31416) 是一种用于研究偏头痛的5-HT1B/1D 受体激动剂。
T0216	Eletriptan hydrobromide Eletriptan HBr,UK-116044,依来曲普坦氢溴酸盐	5-HT Receptor	GPCR/G Protein; Neuroscience
	Eletriptan hydrobromide (Eletriptan HBr) 是一种口服活性激动剂，对 5-HT1B/1D 受体具有特异性亲和力，Ki 值分别为 0.92 和 3.14 nM。
T2317	Almotriptan Malate LAS 31416,PNU180638,马来酸阿莫曲坦	5-HT Receptor	GPCR/G Protein; Neuroscience
	Almotriptan Malate (PNU180638) 是一种选择性 5-HT1B/1D 受体激动剂，用于治疗成人偏头痛发作。
T2395	Vortioxetine 沃替西汀,Lu AA 21004	5-HT Receptor; Serotonin Transporter	GPCR/G Protein; Neuroscience
	Vortioxetine (Lu AA 21004) 是5-HT1A、5-HT1B、5-HT3A、5-HT7受体和 5-羟色胺转运体抑制剂，Ki 值分别为 15、33、3.7、19 和 1.6 nM。它作为抗抑郁药，用于治疗重度抑郁症。
T1092	Zolmitriptan 佐米曲普坦,311C90,BW-311C90	5-HT Receptor	GPCR/G Protein; Neuroscience
	Zolmitriptan (311C90) 是一种5-HT1B/1D 受体部分激动剂，可用于偏头痛的研究，对 5-HT1B、5-HT1D、5-HT1F 受体的Ki 分别为 5.01、0.63 和 63.09 nM。
T23315	SB 216641 hydrochloride SB-216641A,SB-216641 hydrochloride,SB216641A,SB 216641A	5-HT Receptor	GPCR/G Protein; Neuroscience
	SB 216641 hydrochloride (SB-216641A) 是一种选择性的 5-HT1B/D 受体拮抗剂，具有抗焦虑作用，拮抗舒马普坦介导的血管收缩反应。
T2395L	Vortioxetine hydrobromide 氢溴酸沃替西汀,Vortioxetine (Lu AA21004) HBr,Vortioxetine HBr,盐酸沃替西汀,Lu AA21004 hydrobromide	5-HT Receptor; Serotonin Transporter	GPCR/G Protein; Neuroscience
	Vortioxetine hydrobromide (Lu AA21004 hydrobromide) 是5-HT1A、5-HT1B、5-HT3A、5-HT7受体和5-羟色胺转运体(SERT)的抑制剂，Ki 值分别为 15、33、3.7、19 和 1.6 nM。
T6602	Naratriptan hydrochloride Naratriptan HCl,Amerge,Naramig,盐酸那拉曲坦,GR-85548A hydrochloride	5-HT Receptor	GPCR/G Protein; Neuroscience
	Naratriptan hydrochloride (GR-85548A hydrochloride) 是一种5-HT1受体激动剂，有抗偏头疼特性。它还可以通过刺激三叉神经系统感觉神经末梢上的 5-HT1D/1B 受体来发挥其作用，从而减少促炎神经肽的释放。
T4118	SB 271046 hydrochloride SB 271046A	5-HT Receptor	GPCR/G Protein; Neuroscience
	SB 271046 hydrochloride (SB 271046A) 是高效、选择性和具有口服活性的5-HT6受体拮抗剂，对大鼠、猪和人的pKi 分别为 9.02、8.55 和 8.81。它增加额叶皮层中的细胞外天冬氨酸和谷氨酸并表现出抗惊厥活性，EC50为 0.16 μM。它对 5-HT6 受体、结合位点和离子通道的选择性超过 200 倍。
T36949	Niaprazine	5-HT Receptor; Adrenergic Receptor; Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Niaprazine 是有效的组胺 H1 受体拮抗剂，具有抗组胺和抗血清素活性。Niaprazine 在睡眠障碍方面有研究的价值。
T22872	Isamoltane hemifumarate	Others	Others
	5-HT1B antagonist
T23055	NAS181 NAS-181	Others	Others
	rat 5-HT1B receptor antagonist
T22653	CGS 12066B dimaleate	Others	Others
	5-HT1B full agonist
T23405	Sumatriptan	Others	Others
	Sumatriptan succinate is a selective 5-HT1 receptor agonist with specificity towards 5-HT1D, 5-HT1B, and 5-HT1A.
T14190	Alniditan Alnitidan	5-HT Receptor	GPCR/G Protein; Neuroscience
	Alniditan is a receptors agonist of 5-HT1B/1D in HEK 293 cells (IC50: 1.7 and 1.3 nM). For 5-HT1B/1D receptors, the pKi values are 8.96 and 9.40, respectively.
T10360	AR-A 2 AR-A 000002	Others	Others
	AR-A 2 is a selective 5-HT1B receptor antagonist, with a high affinity to guinea pig cortex 5HT1B/1D and recombinant guinea pig 5-HT1B receptors (Ki: 0.24 and 0.47 nM) and with 10-fold lower affinity to guinea pig 5-HT1D receptor (Ki: 5 nM).
T12861L	SB-277011 dihydrochloride SB-277011A dihydrochloride	Dopamine Receptor	GPCR/G Protein; Neuroscience
	SB-277011 dihydrochloride is a potent, selective, orally bioavailable and brain penetrate antagonist of dopamine D3 receptor(pKis of 8.0, 6.0, <5.2 and 5.9 for D3, D2, 5-HT1B, and 5-HT1D receptors, respectively).
T22809	GR 55562 dihydrochloride	Others	Others
	5-HT1B (5-HT1Dβ) silent antagonist
T28678	SB 649915 SB-649915,SB649915	Others	Others
	SB 649915 is a serotonin reuptake inhibitor and 5-HT1A and 5-HT1B receptor antagonist.
T22953	LY 393558	Others	Others
	Dual 5-HT1B/1D receptor antagonist
T10380	AS19	5-HT Receptor	GPCR/G Protein; Neuroscience
	AS19 is a potent, selective 5-HT7 receptor agonist (IC50: 0.83 nM; Ki: 0.6 nM). AS19 is selective for 5-HT7 over 5-HT1A, 5-HT1B, 5-HT1D, and 5-HT5A receptors (Kis: 89.7 nM, 490 nM, 6.6 nM and 98.5 nM, respectively).
T27000	CGS-12066 maleate salt CGS12066,CGS-12066,CGS -12066	Others	Others
	CGS-12066 maleate salt is an agonist of 5-HT1B serotonin receptor.
T24386	L-Alprenolol (-)-Alprenolol,(S)-Alprenolol	Others	Others
	L-Alprenolol is a non-selective beta-blocker and a 5-HT1A and 5-HT1B receptor antagonist.
T21407	Frovatriptan Succinate Frovatriptan succinate hydrate,NCGC00183880-01,Frovatriptan Succinate monohydrate,KB-295988	Others	Others
	Frovatriptan Succinate is a synthetic triptan with 5-HT1B/1D receptors agonist activity. It is indicated for the acute treatment of migraine.
T22524	5-Nonyloxytryptamine oxalate	Others	Others
	5-HT1B agonist
T71103	AZD3676	Others	Others
	AZD3676 is a novel dual antagonist of serotonin 5-HT1A and 5-HT1B receptor.
T70559	GR-127935	Others	Others
	GR-127935 is a potent and selective 5-HT1B/1D receptor antagonist.
T22806	GR 127935 hydrochloride	Others	Others
	5-HT1B/1D receptor antagonist
T71209	CGS 12066A	Others	Others
	CGS 12066A is a drug which acts as a potent and selective agonist for the 5-HT1B receptor with lower affinity for the three 5-HT₂ receptor subtypes. It is used for studying the role of the 5-HT1B receptor in various processes including perception of pain and the sleep-wake cycle.
T27432	GR-55562 dihydrobromide GR 55562 dihydrobromide	Others	Others
	GR-55562 dihydrobromide is a antagonist of 5-HT1B/5-HT1D serotonin receptor.
T28637	S 14506 HCl S14506 HCl,S-14506,S14506HCl	Others	Others
	S 14506 HCl is a highly potent selective 5-HT1A receptor full agonist, pKi values are 9.0, 6.6, 7.5, 6.6 and < 6.0 for 5-HT1A, 5-HT1B, 5-HT1C, 5-HT2 and 5-HT3 receptors respectively.

化合物

Cat.No: TQ0311

Target: Dopamine Receptor, 5-HT Receptor

RU 24969 free base

Cat.No: T8593

Synonym: 5-methoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole

Target: 5-HT Receptor

Cat.No: T4560

Synonym: Alpheprol,阿普洛尔,(RS)-Alprenolol,dl-Alprenolol

Target: 5-HT Receptor, Adrenergic Receptor

Alprenolol hydrochloride

Cat.No: T22236

Synonym: 阿普洛尔盐酸盐,盐酸阿普洛尔

Target: 5-HT Receptor

Cat.No: T8737

Target: 5-HT Receptor

Sumatriptan succinate

Cat.No: T0203

Synonym: 舒马普坦琥珀酸盐,GR 43175,琥珀酸舒马曲坦

Target: 5-HT Receptor

Frovatriptan succinate hydrate

Cat.No: T11326

Synonym: Frovelan,夫罗曲坦琥珀酸盐水合物 ,Frova

Target: 5-HT Receptor

Eltoprazine hydrochloride

Cat.No: T7498

Synonym: 1-(2,3-二氢苯并[B][1,4]二氧杂芑-5-基)哌嗪,DU 28853 hydrochloride

Target: 5-HT Receptor

Cat.No: T11075

Target: 5-HT Receptor

Cat.No: T12861

Synonym: SB-277011A

Target: Dopamine Receptor

Cat.No: T15414

Synonym: GR-113808

Target: 5-HT Receptor

SB-224289 hydrochloride

Cat.No: T12841

Synonym: SB-224289A

Target: 5-HT Receptor

BRL-15572 dihydrochloride

Cat.No: T6423

Synonym: 四氢罂粟碱盐酸盐,BRL 15573 dihydrochloride

Target: 5-HT Receptor

Anpirtoline hydrochloride

Cat.No: T22576

Synonym: D-16949 hydrochloride

Target: 5-HT Receptor

3-(2-aminopropyl)phenol hydrochloride

Cat.No: T50039

Target: Others

Cat.No: T22808

Synonym: 3-[3-[2-二甲基氨基乙基]-1H-吲哚-5-基]-N-[4-甲氧基苄基]丙烯酰胺

Target: 5-HT Receptor

Cat.No: T12847

Synonym: SB-616234A

Target: 5-HT Receptor

Donitriptan hydrochloride

Cat.No: T21666

Synonym: 盐酸多尼普曲坦,Donitriptan HCl,Donitriptan monohydrochloride

Target: 5-HT Receptor

CP94253 hydrochloride

Cat.No: T22689

Synonym: CP 94253 hydrochloride

Target: Others, 5-HT Receptor

Cat.No: T21231

Synonym: 阿莫曲坦,LAS 31416,阿莫曲普坦

Target: 5-HT Receptor

Eletriptan hydrobromide

Cat.No: T0216

Synonym: Eletriptan HBr,UK-116044,依来曲普坦氢溴酸盐

Target: 5-HT Receptor

Almotriptan Malate

Cat.No: T2317

Synonym: LAS 31416,PNU180638,马来酸阿莫曲坦

Target: 5-HT Receptor

Cat.No: T2395

Synonym: 沃替西汀,Lu AA 21004

Target: 5-HT Receptor, Serotonin Transporter

Cat.No: T1092

Synonym: 佐米曲普坦,311C90,BW-311C90

Target: 5-HT Receptor

SB 216641 hydrochloride

Cat.No: T23315

Synonym: SB-216641A,SB-216641 hydrochloride,SB216641A,SB 216641A

Target: 5-HT Receptor

Vortioxetine hydrobromide

Cat.No: T2395L

Synonym: 氢溴酸沃替西汀,Vortioxetine (Lu AA21004) HBr,Vortioxetine HBr,盐酸沃替西汀,Lu AA21004 hydrobromide

Target: 5-HT Receptor, Serotonin Transporter

Naratriptan hydrochloride

Cat.No: T6602

Synonym: Naratriptan HCl,Amerge,Naramig,盐酸那拉曲坦,GR-85548A hydrochloride

Target: 5-HT Receptor

SB 271046 hydrochloride

Cat.No: T4118

Synonym: SB 271046A

Target: 5-HT Receptor

Cat.No: T36949

Target: 5-HT Receptor, Adrenergic Receptor, Histamine Receptor

Isamoltane hemifumarate

Cat.No: T22872

Target: Others

Cat.No: T23055

Synonym: NAS-181

Target: Others

CGS 12066B dimaleate

Cat.No: T22653

Target: Others

Cat.No: T23405

Target: Others

Cat.No: T14190

Synonym: Alnitidan

Target: 5-HT Receptor

Cat.No: T10360

Synonym: AR-A 000002

Target: Others

SB-277011 dihydrochloride

Cat.No: T12861L

Synonym: SB-277011A dihydrochloride

Target: Dopamine Receptor

GR 55562 dihydrochloride

Cat.No: T22809

Target: Others

Cat.No: T28678

Synonym: SB-649915,SB649915

Target: Others

Cat.No: T22953

Target: Others

Cat.No: T10380

Target: 5-HT Receptor

CGS-12066 maleate salt

Cat.No: T27000

Synonym: CGS12066,CGS-12066,CGS -12066

Target: Others

Cat.No: T24386

Synonym: (-)-Alprenolol,(S)-Alprenolol

Target: Others

Frovatriptan Succinate

Cat.No: T21407

Synonym: Frovatriptan succinate hydrate,NCGC00183880-01,Frovatriptan Succinate monohydrate,KB-295988

Target: Others

5-Nonyloxytryptamine oxalate

Cat.No: T22524

Target: Others

Cat.No: T71103

Target: Others

Cat.No: T70559

Target: Others

GR 127935 hydrochloride

Cat.No: T22806

Target: Others

Cat.No: T71209

Target: Others

GR-55562 dihydrobromide

Cat.No: T27432

Synonym: GR 55562 dihydrobromide

Target: Others

Cat.No: T28637

Synonym: S14506 HCl,S-14506,S14506HCl

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-05308	CD45 Protein, Human, Recombinant (aa 1-529, His) GP180,B220,L-CA,protein tyrosine phosphatase, receptor type,...	Human	HEK293 Cells
	CD45 Protein, Human, Recombinant (aa 1-529, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.4 kDa and the accession number is P08575-5.
TMPY-05387	SLAMF7 Protein, Human, Recombinant (hFc) SLAM family member 7,19A,SLAM7,CS1,CD319,CRACC	Human	HEK293 Cells
	SLAMF7 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.1 kDa and the accession number is Q9NQ25-5.
TMPY-04318	GRIK2 Protein, Human, Recombinant (hFc) GLUR6,EAA4,MRT6,GLR6,glutamate receptor, ionotropic, kainate...	Human	HEK293 Cells
	GRIK2 (Glutamate Ionotropic Receptor Kainate Type Subunit 2, also known as GluR6) is a Protein Coding gene. The GRIK2 (one of the kainate receptors) gene resides in a genetic linkage region (6q21) associated with bipolar disorder (BPD). The gene coding for GRIK2 has been suggested as a candidate gene for autism based on its localization in the autism-specific region on chromosome 6q21 and the involvement of receptor protein in cognitive functions like learning and memory. GRIK2 belongs to the gl...
TMPY-05547	SLAMF7 Protein, Human, Recombinant (hFc), Biotinylated CS1,SLAM7,CD319,SLAM family member 7,CRACC,19A	Human	HEK293 Cells
	SLAMF7 Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.1 kDa and the accession number is Q9NQ25-5.
TMPY-05498	SR-BI/SCARB1 Protein, Human, Recombinant (hFc) HDLQTL6,SR-BI,SRB1,CD36L1,CLA-1,CLA1,scavenger receptor clas...	Human	HEK293 Cells
	SR-BI/SCARB1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 73.4 kDa and the accession number is Q8WTV0-5.
TMPJ-00854	ETS1 Protein, Human, Recombinant (His) V-ets Erythroblastosis Virus E26 Oncogene Homolog 1 (Avian),...	Human	E. coli
	ETS1 Protein (ETS1) is a nuclear protein that belongs to the ETS family. Members of this family recognize the core consensus DNA sequence GGAA/T in target genes. Proteins function either as transcriptional activators or repressors of numerous genes. They are involved in stem cell development, cell senescence and death, and tumorigenesis. ETS1 is a transcription factor, containing one ETS DNA-binding domain and one PNT (pointed) domain. it has been shown to interact with TTRAP, UBE2I and Death As...
TMPK-01357	SIRP alpha V5 Protein, Human, Recombinant (His & Avi) MFR,PTPNS1,P84,BIT,MYD-1,MYD1,SHPS-1,SIRPA,SIRP α,SIRP α V	Human	HEK293 Cells
	Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.
TMPK-01363	SIRP alpha V5 Protein, Human, Recombinant (His & Avi), Biotinylated SIRP alpha,MFR,PTPNS1,SIRP α V5,P84,SHPS-1,BIT,CD17...	Human	HEK293 Cells
	Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction. SIRP alpha V5 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian c...

重组蛋白

CD45 Protein, Human, Recombinant (aa 1-529, His)

Cat.No: TMPY-05308

Species: Human

Expression System: HEK293 Cells

SLAMF7 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-05387

Species: Human

Expression System: HEK293 Cells

GRIK2 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-04318

Species: Human

Expression System: HEK293 Cells

SLAMF7 Protein, Human, Recombinant (hFc), Biotinylated

Cat.No: TMPY-05547

Species: Human

Expression System: HEK293 Cells

SR-BI/SCARB1 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-05498

Species: Human

Expression System: HEK293 Cells

ETS1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00854

Species: Human

Expression System: E. coli

SIRP alpha V5 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-01357

Species: Human

Expression System: HEK293 Cells

SIRP alpha V5 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-01363

Species: Human

Expression System: HEK293 Cells

Cat. No.	Product Name	Target	Signaling Pathways
T13308	Vortioxetine D8 Lu AA 21004 D8	Others	Others
	Vortioxetine D8 is a deuterium labeled Vortioxetine. Vortioxetine is an 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT inhibitor (Kis: 15 nM, 33 nM, 3.7 nM, 19 nM and 1.6 nM, respectively).
T71211	Rizatriptan-d6 benzoate salt
	Rizatriptan-d6 is intended for use as an internal standard for the quantification of rizatriptan by GC- or LC-MS. Rizatriptan is an agonist of the serotonin receptor subtypes 5-HT1B and 5-HT1D. It is selective for 5-HT1B and 5-HT1D receptors over 5-HT1A receptors. Rizatriptan induces vasoconstriction in isolated human middle meningeal arteries. In vivo, rizatriptan reduces head grooming, the number of oculotemporal strokes, eye blinking, and one-eye closures in a Cacna1a mutant transgenic mou...
TMIJ-0130	Vortioxetine-d8
	Vortioxetine-d8 是 Vortioxetine 的氘代化合物。Vortioxetine 的 CAS 号为 508233-74-7。Vortioxetine 是5-HT1A、5-HT1B、5-HT3A、5-HT7受体和 5-羟色胺转运体抑制剂，Ki值分别为 15、33、3.7、19 和 1.6 nM。它作为抗抑郁药，用于治疗重度抑郁症。
TMIH-0605	Vortioxetine-d8 2HBr
	Vortioxetine-d8 2HBr 是 Vortioxetine 2HBr 的氘代化合物。Vortioxetine 2HBr 的 CAS 号为 508233-74-7。Vortioxetine 是5-HT1A、5-HT1B、5-HT3A、5-HT7受体和 5-羟色胺转运体抑制剂，Ki值分别为 15、33、3.7、19 和 1.6 nM。它作为抗抑郁药，用于治疗重度抑郁症。

同位素标记化合物

Vortioxetine D8

Cat.No: T13308

Synonym: Lu AA 21004 D8

Target: Others

Rizatriptan-d6 benzoate salt

Cat.No: T71211

Vortioxetine-d8

Cat.No: TMIJ-0130

Vortioxetine-d8 2HBr

Cat.No: TMIH-0605

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