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Cat. No. Product Name Target Signaling Pathways
T84963 -Androstan--ol

NSC 50887

Others Others
-Androstan--ol, a steroidal androgen, demonstrates selective interaction with cellular components, showing affinity for the androgen receptor (AR) with an IC50 of 1.7 µM and activating the pregnane X receptor (PXR) in HepG2 cells with an EC50 of 0.8 µM. It selectively inhibits the hydroxylase activities of 16α- and 6β-hydroxylase over 16β- or 7α-hydroxylase, with IC50 values of 70 and 110 µM, compared to >150 µM for the latter enzymes, indicating a specificity in its enzyme inhibition profil...
T73779 5β-Androstan--ol-17-one

Others Others
5β-Androstan--ol-17-one(-Etiocholanolone;5β-Epiandrosterone),为5β还原型类固醇,主要是脱氢表雄酮(DHEA)的关键代谢物之一。在C57BL/KsJ基因型糖尿病(db/db)小鼠中,该化合物显示出显著的降糖效果,并且具有对神经元的抑制活性。

化合物

-Androstan--ol
Cat.No: T84963
Synonym: NSC 50887
Target: Others
5β-Androstan--ol-17-one
Cat.No: T73779
Synonym:
Target: Others
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