Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T37652 |
5(S),6(R)-DiHETE
|
Others | Others |
5(S),6(R)-DiHETE is a dihydroxy polyunsaturated fatty acid and a nonenzymatic hydrolysis product of leukotriene A4 (LTA4). Mouse liver cytosolic epoxide hydrolase catalyzes the conversion of LTA4 to 5(S),6(R)-DiHETE. It is a weak LTD4 receptor agonist in guinea pig lung membranes. It induces guinea pig ileum contraction with an ED50 value of 1.3 μM. | |||
T37653 |
5(S),6(S)-DiHETE
|
Others | Others |
5(S),6(S)-DiHETE is one of the four diastereomeric 5,6-dihydroxy acids produced from the non-enzymatic hydrolysis of LTA4. 5(S),6(S)-DiHETE does not have significant leukotriene-like activity. |