Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T38064 |
5(S)-HETrE
|
Others | Others |
5(S)-HETrE is produced by the action of 5-LO when mead acid is the substrate. There are no literature reports of the biological activity or further metabolic fate of 5(S)-HETrE. | |||
T37400 |
15(S)-HETrE
|
Others | Others |
15(S)-HETrE is the hydroxy-trienoic acid resulting from 15-lipoxygenation of dihomo-γ-linolenic acid . It is an inhibitor of 5-LO in human PMNL with an IC50 value of 4.6 μM. In RBL cells, 15(S)-HETrE inhibits 5-LO, but is about 1/20 as potent as 15(S)-HpETE. |