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Search Results for " 5'-deoxyadenosine "

Targets Recommended: Others

22

抑制剂 & 化合物

6

天然产物

11

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T60020	5'-Fluoro-5'-deoxyadenosine 5'-Fluoro-5'-deoxy-adenosine	Others	Others
	5'-Fluoro-5'-deoxyadenosine (5'-Fluoro-5'-deoxy-adenosine) 常用作研究放线菌卡特链霉菌的工具。
T21017	5'-Amino-5'-deoxyadenosine 5' Amino 5' deoxyadenosine,5'Amino5'deoxyadenosine,Nsc 238990,NH2dAdo	Apoptosis; Adenosine Receptor	Apoptosis; GPCR/G Protein; Neuroscience
	5'-Amino-5'-deoxyadenosine (NH2dAdo) 是一种针对惰性淋巴系统恶性肿瘤的腺苷激酶抑制剂，具有抗肿瘤和抗癌作用。5'-Amino-5'-deoxyadenosine 的抗癌机制通过抑制 DNA 合成，诱导细胞凋亡 (apoptosis) 等来实现。
T36869	5'-chloro-5'-Deoxyadenosine (hydrate)	Others	Others
	5'-chloro-5'-Deoxyadenosine (hydrate) is a nucleoside analog used as a substrate in polyketide biosynthesis. S-(5'-adenosyl)-L-methionine can be converted to 5'-chloro-5'-deoxyadenosine in a reaction catalyzed by a SAM-dependent chlorinase. Through a 7-step route, 5'-chloro-5'-deoxyadenosine can be converted to chloroethylmalonyl-CoA, which has been shown to be involved in the biosynthesis of the anticancer agent salinosporamide A in the marine bacterium S. tropica.
T85317	dADP disodium 2'-Deoxyadenosine 5'-di-phos-phate disodium	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	dADP disodium (2'-Deoxyadenosine 5'-di-phos-phate disodium) 广泛存在于动植物体内，竞争性抑制细菌多聚腺苷酸聚合酶 (poly(A) polymerase)，参与机体能量循环。
T37106	2'-Deoxyadenosine-5'-triphosphate (sodium salt hydrate)	Others	Others
	2'-Deoxyadenosine-5'-triphosphate (dATP) is a purine nucleotide and derivative of the nucleic acid adenosine 5'-triphosphate .1dATP is a substrate for DNA polymerase in the synthesis of DNA.2It is a noncompetitive inhibitor of ribonucleotide reductases, which provides feedback inhibition during DNA synthesis.1dATP has commonly been used in DNA synthesis, sequencing, and labeling in research applications.3,4dATP accumulates in adenosine deaminase deficiency, a disorder characterized by mutations ...
TNU1255	5’-Azido-5’-deoxyadenosine	Others	Others
	5'-Azido-5'-deoxyadenosine is a Nucleoside Derivative - 5'-Modified nucleoside; Azido-nucleoside.
TNU0881	4’,5’-Didehydro-5’-deoxyadenosine	Others	Others
	4',5'-Didehydro-5'-deoxyadenosine is a Nucleoside Derivative - 5'-Modified nucleoside.
T40696	2'-NH2-ATP 2'-NH2-ATP,2'-Amino-2'-deoxyadenosine-5'-triphosphate	Others	Others
	2'-NH2-ATP (2'-Amino-2'-deoxyadenosine-5'-triphosphate) is an adenosine derivative compound that acts as a weak competitive inhibitor of ATP with a K i value of 2.3 mM. It finds utility in nucleic acid labeling.
TNU1119	N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite	Nucleoside Antimetabolite/Analog	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite 是一种腺嘌呤核苷类似物，具有潜在的血管扩张活性和抗癌活性，可用于研究癌症。
TNU1535	5’-O-DMTr-N6-ethyl-2’-deoxyadenosine	Others	Others
	Nucleoside Derivatives - 6-Modified purine nucleosides, Protected nucleosides with NH2/OH open
TNU1124	5’-O-(4,4’-Dimethoxytrityl)-2’-deoxyadenosine	Others	Others
	5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyadenosine is a Nucleoside Derivative - Protected nucleoside with NH2/OH open.
TNU1536	5’-O-DMTr-N6-ethyl-2’-deoxyadenosine 3’-CED phosphoramidite	Others	Others
	5'-O-DMTr-N6-ethyl-2'-deoxyadenosine 3'-CED phosphoramidite is a Nucleoside Phosphoramidite.
T66118	N6-Benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyadenosine	Others	Others
	N6-Benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyadenosine 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T66118，CAS号为 64325-78-6。
TNU1125	5’-O-(4,4’-Dimethoxytrityl)-3’-O-levulinyl-2’-deoxyadenosine	Others	Others
	Nucleoside Derivatives - Protected nucleosides with NH2/OH open; 3’-Modifed nucleosides; Used for conjugation
TNU1136	3'-O-tert-Butyldimethylsilyl-5'-O-DMT-2'-deoxyadenosine	Others	Others
	3'-O-tert-Butyldimethylsilyl-5'-O-DMT-2'-deoxyadenosine is a Nucleoside Derivative - Protected nucleoside with NH2/OH group open.
TNU1085	N6-Benzoyl-2’-chloro-5’-O-(4,4’-dimethoxytrityl)-2’-deoxyadenosine	Others	Others
	Nucleoside Derivatives - Halo-nucleoside; 2’-Modified nucleoside, Protected nucleosides with NH2/OH open
TNU1026	7-(2-Deoxy-β-D-erythro-pentofuranosyl)-5-fluoro-7H-pyrrolo[2,3-d]pyrimidin-4-amine	Others	Others
	Nucleoside Derivatives - Fluoro-modified nucleosides, 7-Deaza-purine nucleosides
T21018	Anisodine hydrobromide	Others	Others
	5'-Amino-5'-deoxyadenosine is an inhibitor of adenosine kinase.
T35766	SAHO	Others	Others
	SAHO is a sulfoxide form of the methyl donor S-(5'-adenosyl)-L-methionine chloride and a substrate for radical SAM enzymes.1It is reductively cleaved to S-adenosylhomocysteine , 5'-deoxyadenosine , and 5'-thioadenosine sulfenic acid by the radical SAM enzymes NosL or NosN. 1.Mandalapu, D., Ji, X., and Zhang, Q.Reductive cleavage of sulfoxide and sulfone by two radical S-adenosyl-L-methionine enzymesBiochemistry58(1)36-39(2019)
T35767	SAHO2	Others	Others
	SAHO2is a sulfone form of the methyl donor S-(5'-adenosyl)-L-methionine chloride and is a substrate for radical SAM enzymes.1It is reductively cleaved to 5'-deoxyadenosine and 5'-thioadenosine sulfinic acid by the radical SAM enzymes NosL or NosN. 1.Mandalapu, D., Ji, X., and Zhang, Q.Reductive cleavage of sulfoxide and sulfone by two radical S-adenosyl-L-methionine enzymesBiochemistry58(1)36-39(2019)
T78516	NUC-7738	Others	Others
	NUC-7738为3'-脱氧腺苷(3'-dA)的5'-芳氧基氨基磷酸酯前药，其对一组血液癌细胞系表现出有效细胞毒活性，可用于癌症研究。
T83829	2'-Deoxy-1,N6-ethenoadenosine-5'-O-triphosphate sodium ε-dATP
	ε-dATP是一种具有荧光性的嘌呤核苷酸2’-脱氧腺苷-5’-O-三磷酸（dATP）衍生物。它能在50至150µM的浓度范围内诱导初级小鼠脾脏T细胞和B细胞在脂多糖(LPS)或刀豆蛋白A刺激下发生姊妹染色单体交换。ε-dATP已被用于研究乙烯氯诱导的突变过程中模糊碱基配对的情况。相关的ATP衍生物ε-ATP，在300 nm激发下显示415 nm的发射峰值。

化合物

5'-Fluoro-5'-deoxyadenosine

Cat.No: T60020

Synonym: 5'-Fluoro-5'-deoxy-adenosine

Target: Others

5'-Amino-5'-deoxyadenosine

Cat.No: T21017

Synonym: 5' Amino 5' deoxyadenosine,5'Amino5'deoxyadenosine,Nsc 238990,NH2dAdo

Target: Apoptosis, Adenosine Receptor

5'-chloro-5'-Deoxyadenosine (hydrate)

Cat.No: T36869

Target: Others

Cat.No: T85317

Synonym: 2'-Deoxyadenosine 5'-di-phos-phate disodium

Target: DNA/RNA Synthesis

2'-Deoxyadenosine-5'-triphosphate (sodium salt hydrate)

Cat.No: T37106

Target: Others

5’-Azido-5’-deoxyadenosine

Cat.No: TNU1255

Target: Others

4’,5’-Didehydro-5’-deoxyadenosine

Cat.No: TNU0881

Target: Others

Cat.No: T40696

Synonym: 2'-NH2-ATP,2'-Amino-2'-deoxyadenosine-5'-triphosphate

Target: Others

N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite

Cat.No: TNU1119

Target: Nucleoside Antimetabolite/Analog

5’-O-DMTr-N6-ethyl-2’-deoxyadenosine

Cat.No: TNU1535

Target: Others

5’-O-(4,4’-Dimethoxytrityl)-2’-deoxyadenosine

Cat.No: TNU1124

Target: Others

5’-O-DMTr-N6-ethyl-2’-deoxyadenosine 3’-CED phosphoramidite

Cat.No: TNU1536

Target: Others

N6-Benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyadenosine

Cat.No: T66118

Target: Others

5’-O-(4,4’-Dimethoxytrityl)-3’-O-levulinyl-2’-deoxyadenosine

Cat.No: TNU1125

Target: Others

3'-O-tert-Butyldimethylsilyl-5'-O-DMT-2'-deoxyadenosine

Cat.No: TNU1136

Target: Others

N6-Benzoyl-2’-chloro-5’-O-(4,4’-dimethoxytrityl)-2’-deoxyadenosine

Cat.No: TNU1085

Target: Others

7-(2-Deoxy-β-D-erythro-pentofuranosyl)-5-fluoro-7H-pyrrolo[2,3-d]pyrimidin-4-amine

Cat.No: TNU1026

Target: Others

Anisodine hydrobromide

Cat.No: T21018

Target: Others

Cat.No: T35766

Target: Others

Cat.No: T35767

Target: Others

Cat.No: T78516

Target: Others

2'-Deoxy-1,N6-ethenoadenosine-5'-O-triphosphate sodium

Cat.No: T83829

Synonym: ε-dATP

Cat. No.	Product Name	Target	Signaling Pathways
T4971	5'-DEOXYADENOSINE 5′-dAdo,5-脱氧腺嘌呤核苷	Endogenous Metabolite	Metabolism
	5'-Deoxyadenosine (5′-dAdo) 是正常受试者尿液中发现的氧化核苷，氧化核苷代表了用于确定遗传物质损伤程度的生物标志物。
T4737	2'-Deoxyadenosine-5'-monophosphate D-AMP,2′-脱氧腺苷-5′-单磷酸,2'-Deoxyadenosine 5'-monophosphate,2'-脱氧腺苷-5'-单磷酸	Others; Endogenous Metabolite	Metabolism; Others
	2'-Deoxyadenosine-5'-monophosphate (D-AMP) 是一种存在于 DNA 中的脱氧核糖核苷酸，是一种核酸 AMP 衍生物。它能够用于研究 DNA 合成和 DNA 损伤过程中基于腺苷的相互作用。
T40370	2′-Deoxyadenosine 5′-monophosphate disodium	Endogenous Metabolite	Metabolism
	2′-Deoxyadenosine 5′-monophosphate disodium, a nucleic acid AMP derivative, is a deoxyribonucleotide present in DNA. It is employed for researching adenosine-based interactions within DNA synthesis and damage analysis.
T37635	2'-Deoxyadenosine-5'-triphosphate trisodium dATP trisodium	DNA/RNA Synthesis; Endogenous Metabolite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
	2'-Deoxyadenosine-5'-triphosphate trisodium (dATP trisodium) 是一种核苷酸，是 DNA 聚合酶的底物，在细胞中用于 DNA 合成或复制。
T36667	2'-Deoxyadenosine-5'-triphosphate dATP,Deoxyadenosine 5-triphosphate	DNA/RNA Synthesis; Endogenous Metabolite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
	2'-Deoxyadenosine-5'-triphosphate (Deoxyadenosine 5-triphosphate) (dATP) 是一种天然存在的小分子核苷酸，在细胞中用于DNA合成或复制。2'-Deoxyadenosine-5'-triphosphate (dATP) 是 DNA 聚合酶的底物。2'-Deoxyadenosine-5'-triphosphate 通过无活性的 α4beta4 四级结构抑制RNA。2'-Deoxyadenosine-5'-triphosphate 与心肌细胞生长有关。
T8227	5'-Methylthioadenosine Methylthioadenosine,5-脱氧-5-甲硫腺苷,5'-(Methylthio)-5'-deoxyadenosine,5'-Deoxy-5'-(methylthio)adenosine,5'-S-Methyl-5'-thioadenosine	Endogenous Metabolite	Metabolism
	5'-Methylthioadenosine 是由 S-腺苷蛋氨酸在多胺合成过程中生成的核苷，通过抑制肿瘤细胞增殖、侵袭和诱导细胞凋亡来抑制肿瘤，同时控制肿瘤组织的炎症微环境。

天然产物

5'-DEOXYADENOSINE

Cat.No: T4971

Synonym: 5′-dAdo,5-脱氧腺嘌呤核苷

Target: Endogenous Metabolite

2'-Deoxyadenosine-5'-monophosphate

Cat.No: T4737

Synonym: D-AMP,2′-脱氧腺苷-5′-单磷酸,2'-Deoxyadenosine 5'-monophosphate,2'-脱氧腺苷-5'-单磷酸

Target: Others, Endogenous Metabolite

2′-Deoxyadenosine 5′-monophosphate disodium

Cat.No: T40370

Target: Endogenous Metabolite

2'-Deoxyadenosine-5'-triphosphate trisodium

Cat.No: T37635

Synonym: dATP trisodium

Target: DNA/RNA Synthesis, Endogenous Metabolite

2'-Deoxyadenosine-5'-triphosphate

Cat.No: T36667

Synonym: dATP,Deoxyadenosine 5-triphosphate

Target: DNA/RNA Synthesis, Endogenous Metabolite

5'-Methylthioadenosine

Cat.No: T8227

Synonym: Methylthioadenosine,5-脱氧-5-甲硫腺苷,5'-(Methylthio)-5'-deoxyadenosine,5'-Deoxy-5'-(methylthio)adenosine,5'-S-Methyl-5'-thioadenosine

Target: Endogenous Metabolite

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-00567	MTA/SAH nucleosidase Protein, E. coli, Recombinant (His & Myc) S-adenosylhomocysteine nucleosidase,mtnN,5'-methylt...	E. coli	E. coli
	MTA/SAH nucleosidase Protein, E. coli, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 31.8 kDa and the accession number is B7LGM1.
TMPH-00692	MTA/SAH nucleosidase Protein, E. coli O9:H4, Recombinant (His & Myc) 5'-methylthioadenosine nucleosidase,5'-met...	E. coli	E. coli
	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine. Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited b...
TMPH-03702	MTA/SAH nucleosidase Protein, Vibrio cholerae serotype O1, Recombinant (His & Myc) 5'-deoxyadenosine nucleosidase,5'...	Vibrio cholerae	E. coli
	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine. MTA/SAH nucleosidase Protein, Vibrio cholerae serotype O1, Recombinant (His & Myc) is expressed in E. coli expression system wit...
TMPY-05308	CD45 Protein, Human, Recombinant (aa 1-529, His) GP180,B220,L-CA,protein tyrosine phosphatase, receptor type,...	Human	HEK293 Cells
	CD45 Protein, Human, Recombinant (aa 1-529, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.4 kDa and the accession number is P08575-5.
TMPY-05387	SLAMF7 Protein, Human, Recombinant (hFc) SLAM family member 7,19A,SLAM7,CS1,CD319,CRACC	Human	HEK293 Cells
	SLAMF7 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.1 kDa and the accession number is Q9NQ25-5.
TMPY-04318	GRIK2 Protein, Human, Recombinant (hFc) GLUR6,EAA4,MRT6,GLR6,glutamate receptor, ionotropic, kainate...	Human	HEK293 Cells
	GRIK2 (Glutamate Ionotropic Receptor Kainate Type Subunit 2, also known as GluR6) is a Protein Coding gene. The GRIK2 (one of the kainate receptors) gene resides in a genetic linkage region (6q21) associated with bipolar disorder (BPD). The gene coding for GRIK2 has been suggested as a candidate gene for autism based on its localization in the autism-specific region on chromosome 6q21 and the involvement of receptor protein in cognitive functions like learning and memory. GRIK2 belongs to the gl...
TMPY-05547	SLAMF7 Protein, Human, Recombinant (hFc), Biotinylated CS1,SLAM7,CD319,SLAM family member 7,CRACC,19A	Human	HEK293 Cells
	SLAMF7 Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.1 kDa and the accession number is Q9NQ25-5.
TMPY-05498	SR-BI/SCARB1 Protein, Human, Recombinant (hFc) HDLQTL6,SR-BI,SRB1,CD36L1,CLA-1,CLA1,scavenger receptor clas...	Human	HEK293 Cells
	SR-BI/SCARB1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 73.4 kDa and the accession number is Q8WTV0-5.
TMPJ-00854	ETS1 Protein, Human, Recombinant (His) V-ets Erythroblastosis Virus E26 Oncogene Homolog 1 (Avian),...	Human	E. coli
	ETS1 Protein (ETS1) is a nuclear protein that belongs to the ETS family. Members of this family recognize the core consensus DNA sequence GGAA/T in target genes. Proteins function either as transcriptional activators or repressors of numerous genes. They are involved in stem cell development, cell senescence and death, and tumorigenesis. ETS1 is a transcription factor, containing one ETS DNA-binding domain and one PNT (pointed) domain. it has been shown to interact with TTRAP, UBE2I and Death As...
TMPK-01357	SIRP alpha V5 Protein, Human, Recombinant (His & Avi) MFR,PTPNS1,P84,BIT,MYD-1,MYD1,SHPS-1,SIRPA,SIRP α,SIRP α V	Human	HEK293 Cells
	Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.
TMPK-01363	SIRP alpha V5 Protein, Human, Recombinant (His & Avi), Biotinylated SIRP alpha,MFR,PTPNS1,SIRP α V5,P84,SHPS-1,BIT,CD17...	Human	HEK293 Cells
	Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction. SIRP alpha V5 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian c...

重组蛋白

MTA/SAH nucleosidase Protein, E. coli, Recombinant (His & Myc)

Cat.No: TMPH-00567

Species: E. coli

Expression System: E. coli

MTA/SAH nucleosidase Protein, E. coli O9:H4, Recombinant (His & Myc)

Cat.No: TMPH-00692

Species: E. coli

Expression System: E. coli

MTA/SAH nucleosidase Protein, Vibrio cholerae serotype O1, Recombinant (His & Myc)

Cat.No: TMPH-03702

Species: Vibrio cholerae

Expression System: E. coli

CD45 Protein, Human, Recombinant (aa 1-529, His)

Cat.No: TMPY-05308

Species: Human

Expression System: HEK293 Cells

SLAMF7 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-05387

Species: Human

Expression System: HEK293 Cells

GRIK2 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-04318

Species: Human

Expression System: HEK293 Cells

SLAMF7 Protein, Human, Recombinant (hFc), Biotinylated

Cat.No: TMPY-05547

Species: Human

Expression System: HEK293 Cells

SR-BI/SCARB1 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-05498

Species: Human

Expression System: HEK293 Cells

ETS1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00854

Species: Human

Expression System: E. coli

SIRP alpha V5 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-01357

Species: Human

Expression System: HEK293 Cells

SIRP alpha V5 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-01363

Species: Human

Expression System: HEK293 Cells

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