22
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11
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T60020 |
5'-Fluoro-5'-deoxyadenosine
5'-Fluoro-5'-deoxy-adenosine |
Others | Others |
5'-Fluoro-5'-deoxyadenosine (5'-Fluoro-5'-deoxy-adenosine) 常用作研究放线菌卡特链霉菌的工具。 | |||
T21017 |
5'-Amino-5'-deoxyadenosine
5' Amino 5' deoxyadenosine,5'Amino5'deoxyadenosine,Nsc 238990,NH2dAdo |
Apoptosis; Adenosine Receptor | Apoptosis; GPCR/G Protein; Neuroscience |
5'-Amino-5'-deoxyadenosine (NH2dAdo) 是一种针对惰性淋巴系统恶性肿瘤的腺苷激酶抑制剂,具有抗肿瘤和抗癌作用。5'-Amino-5'-deoxyadenosine 的抗癌机制通过抑制 DNA 合成,诱导细胞凋亡 (apoptosis) 等来实现。 | |||
T36869 |
5'-chloro-5'-Deoxyadenosine (hydrate)
|
Others | Others |
5'-chloro-5'-Deoxyadenosine (hydrate) is a nucleoside analog used as a substrate in polyketide biosynthesis. S-(5'-adenosyl)-L-methionine can be converted to 5'-chloro-5'-deoxyadenosine in a reaction catalyzed by a SAM-dependent chlorinase. Through a 7-step route, 5'-chloro-5'-deoxyadenosine can be converted to chloroethylmalonyl-CoA, which has been shown to be involved in the biosynthesis of the anticancer agent salinosporamide A in the marine bacterium S. tropica. | |||
T85317 |
dADP disodium
2'-Deoxyadenosine 5'-di-phos-phate disodium |
DNA/RNA Synthesis | Cell Cycle/Checkpoint; DNA Damage/DNA Repair |
dADP disodium (2'-Deoxyadenosine 5'-di-phos-phate disodium) 广泛存在于动植物体内,竞争性抑制细菌多聚腺苷酸聚合酶 (poly(A) polymerase),参与机体能量循环。 | |||
T37106 |
2'-Deoxyadenosine-5'-triphosphate (sodium salt hydrate)
|
Others | Others |
2'-Deoxyadenosine-5'-triphosphate (dATP) is a purine nucleotide and derivative of the nucleic acid adenosine 5'-triphosphate .1dATP is a substrate for DNA polymerase in the synthesis of DNA.2It is a noncompetitive inhibitor of ribonucleotide reductases, which provides feedback inhibition during DNA synthesis.1dATP has commonly been used in DNA synthesis, sequencing, and labeling in research applications.3,4dATP accumulates in adenosine deaminase deficiency, a disorder characterized by mutations ... | |||
TNU1255 |
5’-Azido-5’-deoxyadenosine
|
Others | Others |
5'-Azido-5'-deoxyadenosine is a Nucleoside Derivative - 5'-Modified nucleoside; Azido-nucleoside. | |||
TNU0881 |
4’,5’-Didehydro-5’-deoxyadenosine
|
Others | Others |
4',5'-Didehydro-5'-deoxyadenosine is a Nucleoside Derivative - 5'-Modified nucleoside. | |||
T40696 |
2'-NH2-ATP
2'-NH2-ATP,2'-Amino-2'-deoxyadenosine-5'-triphosphate |
Others | Others |
2'-NH2-ATP (2'-Amino-2'-deoxyadenosine-5'-triphosphate) is an adenosine derivative compound that acts as a weak competitive inhibitor of ATP with a K i value of 2.3 mM. It finds utility in nucleic acid labeling. | |||
TNU1119 |
N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite
|
Nucleoside Antimetabolite/Analog | Cell Cycle/Checkpoint; DNA Damage/DNA Repair |
N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite 是一种腺嘌呤核苷类似物,具有潜在的血管扩张活性和抗癌活性,可用于研究癌症。 | |||
TNU1535 |
5’-O-DMTr-N6-ethyl-2’-deoxyadenosine
|
Others | Others |
Nucleoside Derivatives - 6-Modified purine nucleosides, Protected nucleosides with NH2/OH open | |||
TNU1124 |
5’-O-(4,4’-Dimethoxytrityl)-2’-deoxyadenosine
|
Others | Others |
5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyadenosine is a Nucleoside Derivative - Protected nucleoside with NH2/OH open. | |||
TNU1536 |
5’-O-DMTr-N6-ethyl-2’-deoxyadenosine 3’-CED phosphoramidite
|
Others | Others |
5'-O-DMTr-N6-ethyl-2'-deoxyadenosine 3'-CED phosphoramidite is a Nucleoside Phosphoramidite. | |||
T66118 |
N6-Benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyadenosine
|
Others | Others |
N6-Benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyadenosine 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T66118,CAS号为 64325-78-6。 | |||
TNU1125 |
5’-O-(4,4’-Dimethoxytrityl)-3’-O-levulinyl-2’-deoxyadenosine
|
Others | Others |
Nucleoside Derivatives - Protected nucleosides with NH2/OH open; 3’-Modifed nucleosides; Used for conjugation | |||
TNU1136 |
3'-O-tert-Butyldimethylsilyl-5'-O-DMT-2'-deoxyadenosine
|
Others | Others |
3'-O-tert-Butyldimethylsilyl-5'-O-DMT-2'-deoxyadenosine is a Nucleoside Derivative - Protected nucleoside with NH2/OH group open. | |||
TNU1085 |
N6-Benzoyl-2’-chloro-5’-O-(4,4’-dimethoxytrityl)-2’-deoxyadenosine
|
Others | Others |
Nucleoside Derivatives - Halo-nucleoside; 2’-Modified nucleoside, Protected nucleosides with NH2/OH open | |||
TNU1026 |
7-(2-Deoxy-β-D-erythro-pentofuranosyl)-5-fluoro-7H-pyrrolo[2,3-d]pyrimidin-4-amine
|
Others | Others |
Nucleoside Derivatives - Fluoro-modified nucleosides, 7-Deaza-purine nucleosides | |||
T21018 |
Anisodine hydrobromide
|
Others | Others |
5'-Amino-5'-deoxyadenosine is an inhibitor of adenosine kinase. | |||
T35766 |
SAHO
|
Others | Others |
SAHO is a sulfoxide form of the methyl donor S-(5'-adenosyl)-L-methionine chloride and a substrate for radical SAM enzymes.1It is reductively cleaved to S-adenosylhomocysteine , 5'-deoxyadenosine , and 5'-thioadenosine sulfenic acid by the radical SAM enzymes NosL or NosN. 1.Mandalapu, D., Ji, X., and Zhang, Q.Reductive cleavage of sulfoxide and sulfone by two radical S-adenosyl-L-methionine enzymesBiochemistry58(1)36-39(2019) | |||
T35767 |
SAHO2
|
Others | Others |
SAHO2is a sulfone form of the methyl donor S-(5'-adenosyl)-L-methionine chloride and is a substrate for radical SAM enzymes.1It is reductively cleaved to 5'-deoxyadenosine and 5'-thioadenosine sulfinic acid by the radical SAM enzymes NosL or NosN. 1.Mandalapu, D., Ji, X., and Zhang, Q.Reductive cleavage of sulfoxide and sulfone by two radical S-adenosyl-L-methionine enzymesBiochemistry58(1)36-39(2019) | |||
T78516 |
NUC-7738
|
Others | Others |
NUC-7738为3'-脱氧腺苷(3'-dA)的5'-芳氧基氨基磷酸酯前药,其对一组血液癌细胞系表现出有效细胞毒活性,可用于癌症研究。 | |||
T83829 |
2'-Deoxy-1,N6-ethenoadenosine-5'-O-triphosphate sodium
ε-dATP |
||
ε-dATP是一种具有荧光性的嘌呤核苷酸2’-脱氧腺苷-5’-O-三磷酸(dATP)衍生物。它能在50至150µM的浓度范围内诱导初级小鼠脾脏T细胞和B细胞在脂多糖(LPS)或刀豆蛋白A刺激下发生姊妹染色单体交换。ε-dATP已被用于研究乙烯氯诱导的突变过程中模糊碱基配对的情况。相关的ATP衍生物ε-ATP,在300 nm激发下显示415 nm的发射峰值。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T4971 |
5'-DEOXYADENOSINE
5′-dAdo,5-脱氧腺嘌呤核苷 |
Endogenous Metabolite | Metabolism |
5'-Deoxyadenosine (5′-dAdo) 是正常受试者尿液中发现的氧化核苷,氧化核苷代表了用于确定遗传物质损伤程度的生物标志物。 | |||
T4737 |
2'-Deoxyadenosine-5'-monophosphate
D-AMP,2′-脱氧腺苷-5′-单磷酸,2'-Deoxyadenosine 5'-monophosphate,2'-脱氧腺苷-5'-单磷酸 |
Others; Endogenous Metabolite | Metabolism; Others |
2'-Deoxyadenosine-5'-monophosphate (D-AMP) 是一种存在于 DNA 中的脱氧核糖核苷酸,是一种核酸 AMP 衍生物。它能够用于研究 DNA 合成和 DNA 损伤过程中基于腺苷的相互作用。 | |||
T40370 |
2′-Deoxyadenosine 5′-monophosphate disodium
|
Endogenous Metabolite | Metabolism |
2′-Deoxyadenosine 5′-monophosphate disodium, a nucleic acid AMP derivative, is a deoxyribonucleotide present in DNA. It is employed for researching adenosine-based interactions within DNA synthesis and damage analysis. | |||
T37635 |
2'-Deoxyadenosine-5'-triphosphate trisodium
dATP trisodium |
DNA/RNA Synthesis; Endogenous Metabolite | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism |
2'-Deoxyadenosine-5'-triphosphate trisodium (dATP trisodium) 是一种核苷酸,是 DNA 聚合酶的底物,在细胞中用于 DNA 合成或复制。 | |||
T36667 |
2'-Deoxyadenosine-5'-triphosphate
dATP,Deoxyadenosine 5-triphosphate |
DNA/RNA Synthesis; Endogenous Metabolite | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism |
2'-Deoxyadenosine-5'-triphosphate (Deoxyadenosine 5-triphosphate) (dATP) 是一种天然存在的小分子核苷酸,在细胞中用于DNA合成或复制。2'-Deoxyadenosine-5'-triphosphate (dATP) 是 DNA 聚合酶的底物。2'-Deoxyadenosine-5'-triphosphate 通过无活性的 α4beta4 四级结构抑制RNA。2'-Deoxyadenosine-5'-triphosphate 与心肌细胞生长有关。 | |||
T8227 |
5'-Methylthioadenosine
Methylthioadenosine,5-脱氧-5-甲硫腺苷,5'-(Methylthio)-5'-deoxyadenosine,5'-Deoxy-5'-(methylthio)adenosine,5'-S-Methyl-5'-thioadenosine |
Endogenous Metabolite | Metabolism |
5'-Methylthioadenosine 是由 S-腺苷蛋氨酸在多胺合成过程中生成的核苷,通过抑制肿瘤细胞增殖、侵袭和诱导细胞凋亡来抑制肿瘤,同时控制肿瘤组织的炎症微环境。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-00567 |
MTA/SAH nucleosidase Protein, E. coli, Recombinant (His & Myc)
S-adenosylhomocysteine nucleosidase,mtnN,5'-methylt... |
E. coli | E. coli |
MTA/SAH nucleosidase Protein, E. coli, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 31.8 kDa and the accession number is B7LGM1. | |||
TMPH-00692 |
MTA/SAH nucleosidase Protein, E. coli O9:H4, Recombinant (His & Myc)
5'-methylthioadenosine nucleosidase,5'-met... |
E. coli | E. coli |
Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine. Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited b... | |||
TMPH-03702 |
MTA/SAH nucleosidase Protein, Vibrio cholerae serotype O1, Recombinant (His & Myc)
5'-deoxyadenosine nucleosidase,5'... |
Vibrio cholerae | E. coli |
Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine. MTA/SAH nucleosidase Protein, Vibrio cholerae serotype O1, Recombinant (His & Myc) is expressed in E. coli expression system wit... | |||
TMPY-05308 |
CD45 Protein, Human, Recombinant (aa 1-529, His)
GP180,B220,L-CA,protein tyrosine phosphatase, receptor type,... |
Human | HEK293 Cells |
CD45 Protein, Human, Recombinant (aa 1-529, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.4 kDa and the accession number is P08575-5. | |||
TMPY-05387 |
SLAMF7 Protein, Human, Recombinant (hFc)
SLAM family member 7,19A,SLAM7,CS1,CD319,CRACC |
Human | HEK293 Cells |
SLAMF7 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.1 kDa and the accession number is Q9NQ25-5. | |||
TMPY-04318 |
GRIK2 Protein, Human, Recombinant (hFc)
GLUR6,EAA4,MRT6,GLR6,glutamate receptor, ionotropic, kainate... |
Human | HEK293 Cells |
GRIK2 (Glutamate Ionotropic Receptor Kainate Type Subunit 2, also known as GluR6) is a Protein Coding gene. The GRIK2 (one of the kainate receptors) gene resides in a genetic linkage region (6q21) associated with bipolar disorder (BPD). The gene coding for GRIK2 has been suggested as a candidate gene for autism based on its localization in the autism-specific region on chromosome 6q21 and the involvement of receptor protein in cognitive functions like learning and memory. GRIK2 belongs to the gl... | |||
TMPY-05547 |
SLAMF7 Protein, Human, Recombinant (hFc), Biotinylated
CS1,SLAM7,CD319,SLAM family member 7,CRACC,19A |
Human | HEK293 Cells |
SLAMF7 Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.1 kDa and the accession number is Q9NQ25-5. | |||
TMPY-05498 |
SR-BI/SCARB1 Protein, Human, Recombinant (hFc)
HDLQTL6,SR-BI,SRB1,CD36L1,CLA-1,CLA1,scavenger receptor clas... |
Human | HEK293 Cells |
SR-BI/SCARB1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 73.4 kDa and the accession number is Q8WTV0-5. | |||
TMPJ-00854 |
ETS1 Protein, Human, Recombinant (His)
V-ets Erythroblastosis Virus E26 Oncogene Homolog 1 (Avian),... |
Human | E. coli |
ETS1 Protein (ETS1) is a nuclear protein that belongs to the ETS family. Members of this family recognize the core consensus DNA sequence GGAA/T in target genes. Proteins function either as transcriptional activators or repressors of numerous genes. They are involved in stem cell development, cell senescence and death, and tumorigenesis. ETS1 is a transcription factor, containing one ETS DNA-binding domain and one PNT (pointed) domain. it has been shown to interact with TTRAP, UBE2I and Death As... | |||
TMPK-01357 |
SIRP alpha V5 Protein, Human, Recombinant (His & Avi)
MFR,PTPNS1,P84,BIT,MYD-1,MYD1,SHPS-1,SIRPA,SIRP α,SIRP α V |
Human | HEK293 Cells |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal. | |||
TMPK-01363 |
SIRP alpha V5 Protein, Human, Recombinant (His & Avi), Biotinylated
SIRP alpha,MFR,PTPNS1,SIRP α V5,P84,SHPS-1,BIT,CD17... |
Human | HEK293 Cells |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction. SIRP alpha V5 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian c... |