Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T35643 |
4-hydroperoxy Cyclophosphamide
4-hydroperoxy Cyclophosphamide,4-OOH-CY |
Others | Others |
4-hydroperoxy Cyclophosphamide (4-OOH-CY) is the active metabolite form of the prodrug Cyclophosphamide. 4-OOH-CY crosslinks DNA and induces T cell apoptosis independent of death receptor activation, but activates mitochondrial death pathways through production of reactive oxygen species (ROS).[1] Formulations containing the prodrug Cyclophosphamide are used to treat lymphomas and autoimmune disorders.[2],[3] |