Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T37093 |
4,9-Anhydrotetrodotoxin
4,9-Anhydrotetrodotoxin,4,9-anhydro-TTX |
Others | Others |
4,9-Anhydrotetrodotoxin (4,9-anhydro-TTX) is a derivative of TTX that selectively blocks inward sodium current through Nav1.6 voltage-activated sodium channels (IC50 = 7.8 nM in Xenopus oocytes). [1][2][3] It demonstrates IC50 values of 1.3, 0.34, 0.99, 78.5, 1.3, and >30 µM for Nav1.2, Nav1.3, Nav1.4, Nav1.5, Nav1.7, and Nav1.8, respectively.[1] |