Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T85257 |
(S)-3'-amino Blebbistatin
meta-amino Blebbistatin,(−)-3'-amino Blebbistatin,m-amino Blebbistatin |
Others | Others |
"(S)-3'-amino Blebbistatin, retaining the active stereochemistry of the less stable and more phototoxic (–)-blebbistatin, serves as a refined selective cell-permeable inhibitor of non-muscle myosin II ATPases. This compound efficaciously inhibits the Mg-ATPase activity and in vitro motility of non-muscle myosin IIA and IIB across several species with IC50s ranging from 0.5-5 µM, and exhibits minimal inhibition against smooth muscle myosin (IC50= 80 µM). Its primary functions include obstructing ... |